The main side effect is graft versus host disease (GvHD) and this can happen in the weeks following the infusion. Although a side effect, GvHD is the response you want as it suggests the DLI has caused an immune response.
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Diarrhea. Jaundice. Nausea and vomiting. Skin rash. Other risks of DLI include myelosuppression (bone marrow suppression). This condition can cause low blood ...
On the other hand, DLI may induce severe adverse effects, including severe GVHD. When our patient complained of dyspnea with fever, we suspected that the ...
The main side effect is graft versus host disease. (GvHD) and this can happen in the weeks following the infusion. Although a side effect, GvHD suggests the DLI ...
Mar 24, 2022 · Unfortunately, two days after the second DLI, we noted progressive cognitive impairment of the child, tremors and somnolence, followed by a ...
Jan 29, 2022 · In the context of T-cell depletion, failing to achieve full donor chimerism (FDC) entails higher risk of graft loss and disease relapse.
Donor lymphocyte infusions also bring with them the risk of increased graft-vs-host disease in the recipient which can be associated with considerable morbidity ...
Most patients do not experience any severe side effects while receiving DLI. In some cases, they may develop a reaction or experience an unpleasant smell due to ...
However, they suggested that IDLI remains a feasible and safe option, as no GVHD or other adverse effects occurred, even in the HLA-haploidentical setting.
Mar 20, 2020 · Other symptoms of chronic GVHD can include: Decreased appetite; Diarrhea; Abdominal (belly) cramps; Weight loss; Yellowing of the skin and eyes ...