A transfer (infusion) of donated lymphocytes (white blood cells) can help manage relapse after bone marrow or stem cell transplant to treat blood cancer.
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What is the purpose of donor lymphocyte infusion?
What is the purpose of DLI?
When to do DLI?
What is DLI for leukemia?
Donor lymphocyte infusion has been used in the management of relapsed hematologic malignancies after allogeneic hematopoietic cell transplantation.
T cells are a type of lymphocyte that can cause an immune response. A DLI is used after a sibling or unrelated stem cell transplant.
Donor lymphocyte infusion (DLI), also known as donor leukocyte or buffy coat infusion, has been used in an attempt to stimulate a donor-versus-leukemia (GVL) ...
Jan 29, 2022 · Donor lymphocyte infusion (DLI) is an adoptive immunotherapy for mixed chimerism (MC) or relapsed disease after reduced-intensity conditioning ...
Donor lymphocyte infusion is an important therapeutic weapon in the arsenal of hematologists treating patients who have relapsed or have refractory disease ...
The donor lymphocytes may kill remaining cancer cells. Donor lymphocyte infusion is used to treat chronic myelogenous leukemia (CML) that has come back and ...
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Oct 15, 2020 · The main indication for DLI was leukemia relapse (73%), followed by mixed chimerism (17%), and pre-emptive/prophylactic use (10%). Ninety ...
DLI may be used for various indications such as relapse after allogeneic hematopoietic cell transplantation (HCT), to prevent disease relapse in the setting of ...
Nov 1, 2023 · Donor lymphocyte infusion may be considered established following allogeneic-hematopoietic cell transplantation (HCT) that was originally ...
