Jan 27, 2022 · Donor lymphocyte infusion (DLI) is a key strategy for the treatment of AML relapse after allogeneic hematopoietic cell transplantation ...
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Donor lymphocyte infusion is a procedure that transfers healthy white blood cells (lymphocytes) from your bone marrow or stem cell donor to your blood.
Being extremely effective in chronic myeloid leukemia, the procedure was less successful in acute myeloid leukemia (AML), although remissions were observed in ...
Donor lymphocyte infusion (DLI) is an important treatment modality in the management of relapsed hematological malignancies after allogeneic hematopoietic ...
DLI alone can lead to a remission in up to 29% of AML patients who relapse post-transplant [12], and remissions can be durable if DLI is administered after ...
Nov 23, 2021 · Donor Lymphocyte Infusion Is a Feasible Way to Improve Survival in Patients with Acute Myeloid Leukemia and Myelodysplastic Syndromes Who ...
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Jan 5, 2023 · Infusion of donor lymphocytes (DLI) has the potential to restore graft-versus-leukemia immunologic surveillance; however, efficacy varies across ...
Oct 12, 2023 · Donor lymphocyte infusion (DLI) is used to induce remission in patients who relapse after allogeneic stem cell transplantation (allo-HSCT).
The regimen of azacitidine and DLI could safely improve the outcomes of relapsed AML/MDS after allo-HSCT, especially in those with signs of early relapse.
DLIs provide a way to enhance the GvL effect. In AML, the use of DLI allows the consolidation of responses in a preemptive manner and the possibility of ...
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