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Association of amyloid-beta with depression or depressive symptoms in older adults without dementia: a systematic review and meta-analysis

This systematic review and meta-analysis suggested that depressive symptoms may be part of the prodromal stage of dementia.
8 months ago

Awareness of Cognitive Decline in Patients With Alzheimer's Disease: A Systematic Review and Meta-Analysis

We propose that patients may be complaining of their initial subtle cognitive changes, but ACD would soon start to decrease.
3 months ago

Mild Cognitive Impairment and Early Alzheimer’s Disease Management and the Role of New Treatments

Psychiatrist.com

Monoclonal antibodies have shown some promise for slowing cognitive decline and adverse brain changes in mild cognitive impairment and early...
10 months ago

Neuropsychiatric Symptoms in Mild Cognitive Impairment and Dementia Due to AD: Relation With Disease Stage and Cognitive Deficits

Background: The interaction between neuropsychiatric symptoms, mild cognitive impairment (MCI), and dementia is complex and remains to be elucidated.
8 months ago

Cingulate white matter mediates the effects of fecal Ruminococcus on neuropsychiatric symptoms in patients with amyloid-positive amnestic mild cognitive impairment

Microbiota-gut-brain axis interacts with one another to regulate brain functions. However, whether the impacts of gut dysbiosis on limbic...
10 months ago

In Postmenopausal Women, Does Depression Increase Alzheimer’s Risk?

Investigators found that depressive symptoms are associated with the amnestic subtype of mild cognitive decline in older adults,...
20 months ago

Validity of CSF alpha-synuclein to predict psychosis in prodromal Alzheimer's disease

BackgroundAlzheimer's disease (AD) accompanied by psychotic symptoms (PS) has a poor prognosis and may be associated with imbalances in key neural proteins...
7 months ago

Psychosis in Alzheimer disease — mechanisms, genetics and therapeutic opportunities

Psychosis is a common and distressing symptom in people with Alzheimer disease, and few safe and effective treatments are available.
33 months ago

Executive function deficits and medial temporal lobe atrophy in late-life depression and Alzheimer’s disease: a comparative study

The objective of this research was to examine the utility of the Trail Making Test (TMT) and the MTA scale in distinguishing between LLD and AD.
8 months ago

Depression—an underrecognized target for prevention of dementia in Alzheimer’s disease

In this article we review epidemiological studies and biological mechanisms linking depression with AD and cognitive decline.
52 months ago