May 17, 2022 · Pragmatic RCTs are needed to assess whether new cardiovascular therapies can reduce all-cause mortality and improve quality of life in routine ...
May 18, 2022 · The need for increased pragmatism in cardiovascular clinical trials. Nat Rev Cardiol. 2022 May 17:1–14. doi: 10.1038/s41569-022-00705-w. Epub ...
The central tenets of pragmatism in RCTs are to test interventions in routine clinical settings, with patients who are representative of broad clinical practice ...
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This Review discusses the benefits and challenges of including pragmatism in the design, conduct and interpretation of randomized controlled trials (RCTs) ...
Pragmatic trials, undertaken in routine practice settings, may provide more relevant evidence to support decision making for most stakeholders, such as patients ...
3 days ago · This Viewpoint discusses pragmatic trials and their role in developing new knowledge that can be broadly applicable throughout the health ...
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We explore the spectrum of pragmatism across cardiovascular clinical trials, highlighting novel innovations and trends over the past decade.
Jul 11, 2022 · In this issue of JAMA Cardiology, Sepehrvand and colleagues use PRECIS to assess how the degree of clinical trial pragmatism has changed in the ...
Randomized clinical trials (RCTs) are the widely accepted gold standard for the rigorous evaluation of a clinical intervention. To date, most RCTs of drugs.
Jan 28, 2020 · Randomized controlled trials that were published in general medicine journals scored higher in pragmatism than those published in CV journals.