Nov 1, 2019 · Some protein-truncating variants in the FANCM gene were described as moderate breast cancer risk factors with a greater risk of TNBC. In the ...
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The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer. Pubmed ID. 31700994 (View this publication on the PubMed ...
In conclusion, we confirmed that the two rare FANCM deleterious variants p.Arg658* and p.Arg1931* are risk factors for ER-negative and TNBC subtypes. Overall ...
Arg658* and p.Arg1931* are risk factors for ER-negative and TNBC subtypes. Overall our data suggest that the effect of truncating variants on breast cancer risk ...
Sep 28, 2021 · FANCM protein truncating variants (PTVs) are emerging as risk factors for ER-negative and triple negative breast cancer.
Arg658* and p.Arg1931* are risk factors for ER-negative and TNBC subtypes. Overall our data suggest that the effect of truncating variants on breast cancer risk ...
Jan 26, 2020 · Germline protein truncating variants (PTVs) in the FANCM gene have been associated with a 2–4-fold increased breast cancer risk in case-control ...
Aug 10, 2024 · We observed that FANCM:p.Arg658* was associated with increased risk of ER-negative disease and TNBC (OR = 2.44, P = 0.034 and OR = 3.79; P = ...
The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer. KConFab, ABCTB Investigators, GEMO Study Collaborators.
We observed that FANCM:p.Arg658* was associated with increased risk of ER-negative disease and TNBC (OR = 2.44, P = 0.034 and OR = 3.79; P = 0.009, respectively) ...