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Efficient bone marrow irradiation and low uptake by non-haematological organs with an yttrium-90-anti-CD66 antibody prior to haematopoietic stem cell transplantation

Nature
We report the results of a Phase I radiation dose escalation study using an yttrium-90 (90Y) labelled anti-CD66 monoclonal antibody given...
4 months ago

Long-Term Effects of a Transplant Using Your Own Stem Cells (autologous transplant)

BMT Infonet |
An autologous stem cell transplant, a transplant that uses your own cells, is a common treatment for patients with multiple myeloma and non-Hodgkin lymphoma...
8 months ago

A Comparison of Allografting with Autografting for Newly Diagnosed Myeloma

The New England Journal of Medicine
We compared a protocol that entailed a hematopoietic stem-cell autograft followed by an allograft from an HLA-identical sibling with a protocol of tandem...
77 months ago

Long-term outcomes of allogeneic stem cell transplant in multiple myeloma | Blood Cancer Journal

Nature
Allogeneic stem cell transplant (allo SCT) for multiple myeloma (MM) is potentially curative in some, while toxic in many others.
13 months ago

Auto-Auto Versus Auto-Allo HSCT in Multiple Myeloma

MedPage Today
Which type of hematopoietic stem cell transplantation does a better job of extending remission and reducing relapse rates in patients with...
49 months ago

Utilization of hematopoietic stem cell transplantation for the treatment of multiple myeloma: a Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus statement

Nature
Over the last two decades, the utilization of various novel therapies in the upfront or salvage settings has continued to improve survival...
75 months ago

Multiple Myeloma

The New England Journal of Medicine
Multiple myeloma, a plasma-cell neoplasm characterized by skeletal destruction, renal failure, anemia, and hypercalcemia, remains incurable.
83 months ago

Extramedullary disease in multiple myeloma - Blood Cancer Journal

Nature
When clonal plasma cells grow at anatomic sites distant from the bone marrow or grows contiguous from osseous lesions that break through the...
36 months ago

Autologous stem cell transplantation in adult patients with intermediate-risk acute myeloid leukemia in first complete remission and no detectable minimal residual disease. A comparative retrospective study with haploidentical transplants of the global committe

Nature
In patients with acute myeloid leukemia (AML) of intermediate-risk (IR) in first remission (CR1) with no measurable residual disease (MRD...
13 months ago

Second allogeneic transplants for multiple myeloma: a report from the EBMT Chronic Malignancies Working Party

Nature
A second allo-HCT using a HLA-identical sibling donor, if available, provides the best transplant outcomes for relapsed myeloma in this setting.
41 months ago