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Allogeneic stem cell transplantation in multiple myeloma: is there still a place?

Frontiers
The introduction of novel agents dramatically improved response and outcomes of multiple myeloma (MM) and led to a sharp decline in the use...
6 months ago

Efficient bone marrow irradiation and low uptake by non-haematological organs with an yttrium-90-anti-CD66 antibody prior to haematopoietic stem cell transplantation

Nature
We report the results of a Phase I radiation dose escalation study using an yttrium-90 (90Y) labelled anti-CD66 monoclonal antibody given...
5 months ago

Bone marrow transplant

Mayo Clinic
Mayo Clinic offers bone marrow transplants for adults and children using their own cells (autologous transplant), cells from a donor (allogeneic transplant) or...
8 months ago

A Comparison of Allografting with Autografting for Newly Diagnosed Myeloma

The New England Journal of Medicine
We compared a protocol that entailed a hematopoietic stem-cell autograft followed by an allograft from an HLA-identical sibling with a protocol of tandem...
79 months ago

The Role of Allogeneic Stem Cell Transplantation in Multiple Myeloma: A Systematic Review of the Literature

Cureus
Allogeneic stem cell transplant (allo-SCT), through graft versus myeloma (GVM) effects, has the potential to induce remission to a potentially curative-like...
38 months ago

Long-Term Effects of a Transplant Using Your Own Stem Cells (autologous transplant)

BMT Infonet |
An autologous stem cell transplant, a transplant that uses your own cells, is a common treatment for patients with multiple myeloma and non-Hodgkin lymphoma...
10 months ago

Alexandra Gomez-Arteaga, MD, on The Benefit of Orca-T Over PTCy HCT

CGTLiveŽ
“Currently for myeloablative conditioning, there's no real standard way of how we do GVHD prophylaxis. While last year the findings at ASH...
9 months ago

Long-term outcomes of allogeneic stem cell transplant in multiple myeloma | Blood Cancer Journal

Nature
Allogeneic stem cell transplant (allo SCT) for multiple myeloma (MM) is potentially curative in some, while toxic in many others.
15 months ago

First-Line Allogeneic Stem Cell Transplantation for Multiple Myeloma With Chromosome 13q Deletion

Hematology Advisor
A recent study examined treatment outcomes for patients with newly diagnosed multiple myeloma and chromosome 13q deletion (del13q).
62 months ago

The role of transplantation in Hodgkin lymphoma

Frontiers
In this review, we explore the impact of salvage therapy on autoHCT, conditioning regimens, maintenance therapy and the diminishing role of alloHCT for...
17 months ago