The A673T variant is extremely rare in US cohorts and does not play a substantial role in risk for AD in this population.
Rarity of the Alzheimer disease-protective APP A673T variant in the ...
pubmed.ncbi.nlm.nih.gov › ...
The A673T variant is extremely rare in US cohorts and does not play a substantial role in risk for AD in this population.
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OBJECTIVE: To determine the frequency of the APP A673T variant in a large group of elderly cognitively normal controls and AD cases from the United States and ...
CONCLUSIONS AND RELEVANCE: The A673T variant is extremely rare in US cohorts and does not play a substantial role in risk for AD in this population. This ...
RESULTS The A673T variant genotypes were evaluated in 8943 US AD cases, 10 480 US cognitively normal controls, 862 Swedish AD cases, and 707 Swedish cognitively ...
Rarity of the Alzheimer Disease-Protective APP A673T Variant in the United States. 2015. Wang, Li-San;; Naj, Adam C;; Graham, Robert R;; Crane, Paul K; ...
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Jun 15, 2023 ˇ The rare A673T variant was the first variant found within the amyloid precursor protein (APP) gene conferring protection against Alzheimer's disease (AD).
Rarity of the Alzheimer disease-protective APP A673T variant in the United States. ... Humans ˇ Male ˇ Pedigree ˇ Protective Factors ˇ Sweden ˇ United States.
Feb 1, 2015 ˇ CONCLUSIONS AND RELEVANCE The A673T variant is extremely rare in US cohorts and does not play a substantial role in risk for AD in this ...