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Allogeneic stem cell transplantation in multiple myeloma: is there still a place?

Frontiers
The introduction of novel agents dramatically improved response and outcomes of multiple myeloma (MM) and led to a sharp decline in the use of allogeneic...
7 months ago

Prognostic factors impacting post-transplant outcomes in adult T-cell acute lymphoblastic leukemia: a registry-based study by the EBMT acute leukemia working party | Bone Marrow Transplantation

Nature
T-cell acute lymphoblastic leukemia (T-ALL) predominantly affects individuals in late childhood and young adulthood. Allogeneic hematopoietic stem cell...
7 months ago

Cardiovascular Management of Patients Undergoing Hematopoietic Stem Cell Transplantation: From Pretransplantation to Survivorship: A Scientific Statement From the American Heart Association

American Heart Association Journals
Hematopoietic stem cell transplantation can cure various disorders but poses cardiovascular risks, especially for elderly patients and those with...
10 months ago

Donor lymphocyte infusion after allogeneic haematopoietic cell transplantation for haematological malignancies: basic considerations and best practice recommendations from the EBMT

The Lancet
Since the early description of three patients with relapsed leukaemia after allogeneic haematopoietic cell transplantation (HCT) who obtained complete...
7 months ago

Myelofibrosis and allogeneic transplantation: critical points and challenges

Frontiers
In the present review, we will analyze the main controversial points of allogeneic transplantation in MF, that is, the development of more sophisticated models.
6 months ago

Influence of comorbidities on outcome in 1102 patients with an allogeneic hematopoietic stem cell transplantation

Nature
Our study is a retrospective analysis of pre-existing comorbidities assessing the relevance of the HCT-CI on the outcome of consecutive patients.
5 months ago

Annual Meeting of the European Society for Blood and Marrow Transplantation: Physicians - Oral Session (O009-O154)

Nature
We performed a monocentric retrospective study including relapsing (R-)MS patients (primary-progressive MS excluded) treated with AHSCT in Florence between...
3 months ago

Therapeutic options for chronic myeloid leukemia following the failure of second-generation tyrosine kinase inhibitor therapy

Frontiers
This review will primarily focus on exploring treatment options for patients who fail second-generation TKI therapy due to true resistance.
5 months ago

Measurable residual disease (MRD)-testing in haematological and solid cancers - Leukemia

Nature
MRD-testing attempts to quantify residual cancer cells when the cancer is no longer detectable by conventional methods including blood tests, biopsy or...
8 months ago

Safety but limited efficacy of donor lymphocyte infusion for post-transplantation cyclophosphamide-treated patients

Nature
The therapeutic efficacy of donor lymphocyte infusions (DLIs) given after allogeneic hematopoietic cell transplantation (HCT) is limited by risk of...
5 months ago