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Validation of the revised IPSS at transplant in patients with myelodysplastic syndrome/transformed acute myelogenous leukemia receiving allogeneic stem cell transplantation: a retrospective analysis of the EBMT chronic malignancies working party

Nature
The International Prognostic Scoring System has been revised (IPSS-R) to predict prognosis of patients with myelodysplastic syndromes at...
88 months ago

Allogeneic stem cell transplantation in multiple myeloma: is there still a place?

Frontiers
The introduction of novel agents dramatically improved response and outcomes of multiple myeloma (MM) and led to a sharp decline in the use...
7 months ago

Long-term outcomes of allogeneic stem cell transplant in multiple myeloma | Blood Cancer Journal

Nature
Allogeneic stem cell transplant (allo SCT) for multiple myeloma (MM) is potentially curative in some, while toxic in many others.
17 months ago

Myelofibrosis and allogeneic transplantation: critical points and challenges

Frontiers
In the present review, we will analyze the main controversial points of allogeneic transplantation in MF, that is, the development of more sophisticated models.
7 months ago

A clinical perspective on plasma cell leukemia; current status and future directions

Nature
Primary plasma cell leukemia (pPCL) is an aggressive plasma cell disorder with a guarded prognosis. The diagnosis is confirmed when peripheral blood plasma...
47 months ago

Graft-versus-Leukemia Effect Following Hematopoietic Stem Cell Transplantation for Leukemia

Frontiers
The success of hematopoietic stem cell transplantation (HSCT) lies with the ability of the engrafting immune system to remove residual leukemia cells via a...
11 months ago

Second allogeneic transplants for multiple myeloma: a report from the EBMT Chronic Malignancies Working Party

Nature
A second allo-HCT using a HLA-identical sibling donor, if available, provides the best transplant outcomes for relapsed myeloma in this setting.
44 months ago

The role of transplantation in Hodgkin lymphoma

Frontiers
Despite the success of frontline anthracycline-based chemotherapy for classical Hodgkin Lymphoma (cHL), approximately 15% of patients do not achieve an...
18 months ago

Extramedullary disease in multiple myeloma - Blood Cancer Journal

Nature
When a sub-clone of PCs is able to grow outside of marrow, it results in development of disease outside the marrow, termed as extramedullary multiple myeloma (...
39 months ago

Pharmacologic Therapies to Prevent Relapse of Acute Myeloid Leukemia After Allogeneic Hematopoietic Stem Cell Transplantation

Frontiers
Relapse is the main cause of mortality in patients with acute myeloid leukemia (AML) after allogeneic hematopoietic stem cell transplantation (allo-HSCT).
18 months ago