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Indirect Targeting of Subthalamic Deep Brain Stimulation Guided by Stereotactic Computed Tomography and Microelectrode Recordings in Patients With Parkinson’s Disease

Frontiers
Objective: Magnetic resonance imaging fusion techniques guided by frame-based stereotactic computed tomography and microelectrode recordings are widely used...
5 months ago

Deep Brain Stimulation for Parkinson Disease: Overview, Mechanism of Action, Advantages and Disadvantages

Medscape
DBS is used for patients with PD of at least 4 years' duration and 4 months of motor complications, and can improve tremor, rigidity, slowness of movement, and...
47 months ago

Image-guided programming deep brain stimulation improves clinical outcomes in patients with Parkinson’s disease

Nature
Deep brain stimulation (DBS) is an effective treatment for patients with Parkinson's disease (PD). However, some patients may not respond...
10 months ago

Local field potentials of subthalamic nucleus contain electrophysiological footprints of motor subtypes of Parkinson’s disease

PNAS
Although motor subtypes of Parkinson's disease (PD), such as tremor dominant (TD) and postural instability and gait difficulty (PIGD),...
75 months ago

Subthalamic and pallidal deep brain stimulation for Parkinson’s disease—meta-analysis of outcomes

Nature
Although deep brain stimulation (DBS) of the globus pallidus internus (GPi) and the subthalamic nucleus (STN) has become an established...
38 months ago

Intraoperative microelectrode recording under general anesthesia guided subthalamic nucleus deep brain stimulation for Parkinson's disease: One institution's experience

Frontiers
GA is viable and comparable to LA in MER guided STN-DBS for PD, regarding electrode implantation accuracy, clinical outcome and adverse events.
9 months ago

Deep Brain Stimulation and Microelectrode Recording for the Treatment of Parkinson’s Disease

Cureus
DBS is currently used to treat severe motor fluctuations or tremors in advanced stages of PD with the STN or GPi as the primary nuclei to target in the...
27 months ago

Fig. 1. Medtronic No. 3387 quadripolar lead. Each silver band is

ResearchGate
In this study, a new system was evaluated for implanting deep-brain stimulators based on a one-piece platform for each trajectory customized from a...
81 months ago

Randomized, Double-Blind Assessment of LFP Versus SUA Guidance in STN-DBS Lead Implantation: A Pilot Study

Frontiers
Background: The efficacy of deep brain stimulation (DBS) therapy in Parkinson's disease (PD) patients is highly dependent on the precise...
53 months ago

Mapping of subthalamic nucleus using microelectrode recordings during deep brain stimulation

Nature
MER can be used for STN mapping and intraoperative decisions for the implantation of DBS electrode leads with a high accuracy.
48 months ago