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4 days ago · If only regarding consent as necessary to inform about added risks of experimentation, consent may be waived or simplified in pragmatic trials between low-risk ...
1 day ago · One of the key legal and ethical barriers to conducting trials was the Norwegian Health Research Act, which demands informed consent from all participants. The ...
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Oct 5, 2024 · Pragmatic trials are designed to study real-world practice and therefore represent less-perfect experiments than efficacy trials; they sacrifice internal ...
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Sep 30, 2024 · Of course, trials are not always optimally designed to achieve a pragmatic or explanatory aim. It may be optimal in some aspects, but less in others. This ...
Sep 23, 2024 · The question of consent is also crucial. Some argue for waiving consent in pragmatic RCTs due to perceived minimal risks, but this perspective is flawed.
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Sep 16, 2024 · Clinical evidence generation from and for representative populations can be improved through increased research access and ease of trial participation.
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Sep 27, 2024 · During this phone call, any unanswered questions are clarified. Interested participants must then submit a written informed consent to the study nurse and ...
4 days ago · Obtaining informed consent isn't going to be pragmatic; it is time-consuming, challenging, and individualized. Constrained funding in the feasibility phase ...
Sep 18, 2024 · The trial is approved by the Emory University Institutional Review Board, with waiver of informed consent given the minimal risk and impracticability of ...
Sep 22, 2024 · Pragmatic trials are designed to test effectiveness of inter- ventions in real-life clinical practice settings, to maximise applicability and generalisability ...