Donor lymphocyte infusion has been used in the management of relapsed hematologic malignancies after allogeneic hematopoietic cell transplantation.

Comparison of single-dose and escalating-dose regimens of donor lymphocyte infusion for relapse after allografting for chronic myeloid leukemia. Blood. 2000 ...

The incidence of GVHD can also be reduced by starting with low doses of donor cells and “escalating” subsequent doses as required. However, the identification ...

Jul 15, 2002 · Donor lymphocyte infusion (DLI) can produce durable remissions in patients with chronic myelogenous leukemia (CML) who have a relapse after an allogeneic stem ...

Jul 2, 2021 · Prophylactic/preemptive low-dose azacitidine and donor lymphocyte infusion can be readily and safely administered with an acceptable incidence ...

Sep 21, 2016 · Purpose To evaluate the role of donor lymphocyte infusion (DLI) in the treatment of relapsed acute myeloid leukemia (AML) after allogeneic ...

Dec 5, 2014 · Adoptive immunotherapy evaluating escalating doses of donor leukocytes for relapse of chronic myeloid leukemia after bone marrow ...

This group concluded that doses of 1 x 107 cells/kg were a reasonable starting point, with the option of escalating doses with subsequent infusions to achieve ...

Comparison of single-dose and · escalating-dose regimens of donor lymphocyte infusion for relapse · after allografting for chronic myeloid leukemia. Blood. 2000 ...

Jan 5, 2023 · If DLI is administered earlier than 6 months after transplant, the starting cell dose should be adjusted on a case-by-case basis to minimize the ...