Oct 12, 2020 · Our study reveals new putative susceptibility genes and provides new insight into the biological mechanisms underlying CRC development.

Our study reveals new putative susceptibility genes and provides new insight into the biological mechanisms underlying CRC development.

Oct 12, 2020 · This large-scale transcriptome-wide association study (TWAS) has revealed 25 putative susceptibility genes, including five in novel loci and an ...

Our study reveals new putative susceptibility genes and provides new insight into the biological mechanisms underlying CRC development.

We applied the gene-expression prediction models and GWAS data to evaluate associations of genetically predicted gene-expression with CRC risk in 58,131 CRC ...

We identified 25 genes associated with CRC risk at a Bonferroni-corrected threshold of P < 9.1 × 10–6, including genes in 4 novel loci, PYGL (14q22.1), RPL28 ( ...

This proposed study will provide strong evidence for pinpointing CRC susceptibility genes, thereby facilitating the translation of our findings to cancer ...

Identifying Novel Susceptibility Genes for Colorectal Cancer Risk From a Transcriptome-Wide Association Study of 125,478 Subjects · List of references.

Identifying Novel Susceptibility Genes for Colorectal Cancer Risk From a Transcriptome-Wide Association Study of 125,478 Subjects. Gastroenterology. Vol. 160 ...

Susceptibility genes and the underlying mechanisms for the majority of risk loci identified by genome-wide association studies (GWAS) for colorectal cancer ...