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Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma

Nature
Survival following a diagnosis of multiple myeloma (MM) varies between patients and some of these differences may be a consequence of...
106 months ago

Genome-wide association study identifies multiple susceptibility loci for multiple myeloma

Nature
Multiple myeloma (MM) is a plasma cell malignancy with a significant heritable basis. Genome-wide association studies have transformed our...
101 months ago

Efficient and accurate frailty model approach for genome-wide survival association analysis in large-scale biobanks

Nature
With decades of electronic health records linked to genetic data, large biobanks provide unprecedented opportunities for systematically...
26 months ago

Functional dissection of inherited non-coding variation influencing multiple myeloma risk

Nature
We demonstrate that MM susceptibility is mediated by gene-regulatory changes in plasma cells and B-cells, and identify putative causal variants at six risk...
34 months ago

Genome-wide identification of potential biomarkers in multiple myeloma using meta-analysis of mRNA and miRNA expression data

Nature
We have conducted genome-wide meta-analysis of DEGs/DEMs in MM versus Normal Plasma Cells (NPCs) and derived unified putative signatures for MM.
42 months ago

Cancer health disparities in racial/ethnic minorities in the United States | British Journal of Cancer

Nature
In this review, we summarise reported disparities and associated factors in the United States of America (USA) for the most common cancers.
50 months ago