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Genome-wide association studies identify four ER negative–specific breast cancer risk loci
Nature
Montserrat Garcia-Closas and colleagues report a meta-analysis of three genome-wide association studies for estrogen receptor (ER)-negative...
139 months ago
Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers
Nature
Circulating proteins can reveal key pathways to cancer and identify therapeutic targets for cancer prevention.
6 months ago
Genome-wide and transcriptome-wide association studies of mammographic density phenotypes reveal novel loci
Breast Cancer Research
Mammographic density (MD) phenotypes, including percent density (PMD), area of dense tissue (DA), and area of non-dense tissue (NDA),...
31 months ago
New role of fat-free mass in cancer risk linked with genetic predisposition
Nature
Cancer risk is associated with the widely debated measure body mass index (BMI). Fat mass and fat-free mass measurements from bioelectrical...
7 months ago
Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer
Nature
We identify 26 previously unreported, likely target genes of overall breast cancer risk variants, and 17 for estrogen receptor (ER)-negative breast cancer.
66 months ago
Identification of two novel breast cancer loci through large-scale genome-wide association study in the Japanese population
Nature
This well-powered GWAS is a representative study to identify SNPs that are associated with breast cancer in the Japanese population.
59 months ago
Functional annotation of breast cancer risk loci: current progress and future directions
Nature
Genome-wide association studies coupled with large-scale replication and fine-scale mapping studies have identified more than 150 genomic...
36 months ago
Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk
Nature
Linkage and candidate gene studies have identified several breast cancer susceptibility genes, but the overall contribution of coding...
14 months ago
Genome-wide association study of breast cancer in Latinas identifies novel protective variants on 6q25
Nature
The genetic contributions to breast cancer development among Latinas are not well understood. Here we carry out a genome-wide association...
120 months ago
Variable expression quantitative trait loci analysis of breast cancer risk variants
Nature
Genome wide association studies (GWAS) have identified more than 180 variants associated with breast cancer risk, however the underlying...
43 months ago