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Jul 22, 2012 · Applying Smart-Seq to circulating tumor cells from melanomas, we identified distinct gene expression patterns, including candidate biomarkers ...
Applying Smart-Seq to circulating tumor cells from melanomas, we identified distinct gene expression patterns, including candidate biomarkers for melanoma ...
People also ask
What is the difference between RNA-Seq and mRNA seq?
Total RNA-Seq provides the most comprehensive transcriptome analysis by capturing all RNA species present in the sample, including non-coding RNAs and alternative splicing variants. On the other hand, mRNA-Seq focuses specifically on protein-coding transcripts, providing superior data on the coding regions of genes.
What is single cell rna-seq analysis for cancer?
Single-cell RNA-sequencing (scRNA-seq) has revolutionized our understanding of complex biological systems. In cancer, a combination of intrinsic genetic and epigenetic variation with extrinsic and spatial factors creates a paragon of biological complexity.
What is the difference between RNA-Seq and single cell rna-seq?
So, Bulk RNA sequencing (bulk RNA-seq) provides an average gene expression profile for a population of cells, while Single-cell RNA sequencing (scRNA-seq) allows for the study of gene expression in individual cells.
What is RNA sequencing in cancer diagnosis?
Cancer RNA-Seq can help scientists: Determine which variants are expressed in cancer samples. Identify gene expression signatures and mutational profiles associated with individual tumors, single cells, and tumor types.
Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells. Nat Biotechnol. 2020 Mar;38(3):374.
Applying Smart-Seq to circulating tumor cells from melanomas, we identified distinct gene expression patterns, including candidate biomarkers for melanoma ...
We developed two new methods to accomplish the single cell sequencing: a novel cell-capture system to isolate rare circulating tumor cells from blood, and a new ...
Feb 3, 2020 · Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells. Nat Biotechnol 38, 374 (2020).
Mapping and quantifying mammalian transcriptomes by RNA-Seq. · Full-length RNA-seq from single cells using Smart-seq2. · Derivation of blood-brain barrier ...
Applying Smart-Seq to circulating tumor cells from melanomas, it is found that although gene expression estimates from single cells have increased noise, ...
Applying Smart-Seq to circulating tumor cells from melanomas, we identified distinct gene expression patterns, including candidate biomarkers for melanoma ...
We determined the sensitivity and quantitative accuracy of Smart-Seq for single-cell transcriptomics by evaluating it on total RNA dilution series. We found ...