Jul 10, 2024 · Exploring the genetics of lithium response in bipolar disorders · Herrera-Rivero, M. · Adli, M. · Akiyama, K. · Akula, N. · Amare, A. T. · Ardau, R.
The mood stabilizer lithium represents a cornerstone in the long term treatment of bipolar disorder (BD), although with substantial interindividual ...
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Aug 19, 2009 · While molecular studies have provided important information about possible genes involved in BD predisposition or in lithium response, neither ...
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Jun 21, 2017 · Lithium is the most successful mood stabilizer treatment for bipolar disorder. However, unlike conventional drugs that are designed to ...
Nov 9, 2017 · In the cross-trait meta-GWAS, 15 genetic loci that may have overlapping effects on lithium treatment response and susceptibility to SCZ were ...
Mar 24, 2021 · Six genome-wide association studies (GWAS) reviewed here present evidence of genetic variations related to lithium responsivity and side effect expression.
Jun 29, 2024 · Lithium (Li) remains the treatment of choice for bipolar disorders (BP). Its mood-stabilizing effects help reduce the long-term burden of ...
Apr 6, 2022 · The findings may provide clues to how lithium works, as the AKAP-11 protein is known to interact with a molecular pathway modified by the drug.
Jun 12, 2024 · Abstract Background Lithium (Li) remains the treatment of choice for bipolar disorders (BP). Its mood-stabilizing effects help reduce the ...