Jul 6, 2023 ˇ This investigation suggests that current GW-PRS approaches may not improve the ability to predict prostate cancer risk compared to the PRS 269 developed from ...
Findings from this investigation suggest that current GW-PRS approaches do not outperform the multi-ancestry PRS269 for overall prostate cancer risk prediction.
Each SD unit increase in PRS was associated with 1.83-fold higher odds of prostate cancer (95% CI = 1.67–2.00) in men of African ancestry and 2.19-fold higher ...
Jun 12, 2023 ˇ (A–D) PRS performance is evaluated using area under the curve (AUC) estimated in men of (A) African and (C) European ancestry and OR of prostate ...
Jun 12, 2023 ˇ Our findings suggest that in men of African and European ancestry, genome-wide polygenic risk scores including >1 million variants are not more ...
Jul 6, 2023 ˇ We compared the predictive ability of several GW-PRS approaches to a recently developed PRS of 269 established prostate cancer-risk variants ...
Jan 29, 2024 ˇ We compared the predictive ability of several GW-PRS approaches to a recently developed PRS of 269 established prostate cancer-risk variants ...
Aug 2, 2023 ˇ Burcu Darst explores her team's study on developing polygenic risk scores for prostate cancer in men of African and European ancestry.
May 15, 2023 ˇ We compared the predictive ability of several GW-PRS approaches to a recently developed PRS of 269 established prostate cancer risk variants ...
Aug 5, 2024 ˇ We compared the predictive ability of several GW-PRS approaches to a recently developed PRS of 269 established prostate cancer-risk variants ...