6 days ago · Refractory or relapsed T cell acute lymphoblastic leukemia (r/r T-ALL) patients have poor prognoses, due to the lack of effective salvage therapies.

5 days ago · Elevated donor plasminogen activator inhibitor-1 levels are associated with the risk of primary graft dysfunction.

6 days ago · On day 3, T cells were transferred into new 24-well tissue culture–treated plates and subsequently expanded with IL7 and IL15 (10 ng/mL each). Each donor was ...

6 days ago · Pre-treatment serum IL-10 predicts the risk of secondary central nervous system involvement in patients with diffuse large B-cell lymphoma. Circulating IL-10 is ...

2 days ago · Essentially, post-transplantation, donor HSCs predominantly produce neutrophils, which serve dual roles in infection control and the bone marrow vessel repair, ...

6 days ago · It is used in the treatment of chronic lymphocytic leukemia (CLL) because the cancerous cells of CLL are usually CD20-expressing B-cells.

7 days ago · Although hyper-CVAD therapy was unsuccessful, induction treatment with idarubicin and cytarabine resulted in complete remission (CR). The patient subsequently ...

1 day ago · Abstract. The histone methyltransferase enhancer of zeste homolog 2 (EZH2) plays important roles in T-cell differentiation, proliferation and function.

6 days ago · The approval was backed by the Phase II open-label AGAVE-201 trial, where treatment with a 0.3-mg/kg dose of Niktimvo elicited an overall response rate of 75%, ...