4 days ago · This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis.
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What is the function of transferrin receptor protein 1?
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Jan 25, 2021 · The human transferrin receptor 1 (TfR) is central in maintaining adequate cellular iron levels with the iron carrier proteins transferrin (Tf) ...
Apr 20, 2021 · We describe a design strategy to target proteins containing an exposed beta edge strand. We use the approach to design binders to the human transferrin ...
Binding of transferrin to the receptor is regulated by hereditary hemochromatosis protein (HFE), an iron regulatory protein that partly shares a binding site ...
This atomic model shows that Tf binds laterally to the TfR1 dimer and extends into the gap between the bottom of the receptor ectodomain and the membrane.
Mar 8, 2019 · Human transferrin receptor 1 (CD71) guarantees iron supply by endocytosis upon binding of iron-loaded transferrin and ferritin.
CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily.
Jan 25, 2021 · The human transferrin receptor 1 (TfR) is central in maintaining adequate cellular iron levels with the iron carrier proteins transferrin (Tf) ...
Dec 4, 2021 · One of the designed proteins, TB08, was further optimized computationally and experimentally to identify variants with improved binding to TfR.
Apr 20, 2021 · We describe a design strategy to target proteins containing an exposed beta edge strand. We use the approach to design binders to the human transferrin ...
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