Conclusion: There is little evidence that any of the evaluated candidate variants act as modifiers of breast and/or ovarian cancer risk in BRCA1 or BRCA2 ...
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SNP rs2981582 in FGFR2 is strongly associated with risk of breast cancer and acting as a risk modifier in BRCA2 mutation carriers. Rs2981582 may also influence ...
Oct 21, 2014 · There is little evidence that any of the evaluated candidate variants act as modifiers of breast and/or ovarian cancer risk in BRCA1 or BRCA2 ...
We review the latest evidence regarding genetic modifiers of cancer risk for female BRCA1 and BRCA2 mutation carriers emerging from candidate gene studies.
CONCLUSION: There is little evidence that any of the evaluated candidate variants act as modifiers of breast and/or ovarian cancer risk in BRCA1 or BRCA2 ...
Sep 28, 2016 · Women who carry a genetic mutation in the BRCA1 gene have a substantially increased risk of developing ovarian cancer in comparison with women who do not have ...
Feb 17, 2021 · About 50 common variants have been shown to modify BC risk for mutation carriers. All but three, were identified in general population studies.
Conclusion: There is little evidence that any of the evaluated candidate variants act as modifiers of breast and/or ovarian cancer risk in BRCA1 or BRCA2 ...
Apr 19, 2007 · Female carriers of deleterious BRCA1 and BRCA2 mutations are predisposed to high lifetime risks of breast and ovarian cancer. Initial estimates ...
There is little evidence that any of the evaluated candidate variants act as modifiers of breast and/or ovarian cancer risk in BRCA1 or BRCA2 mutation carriers.