Jan 11, 2022 ˇ By age 85 years, for BRCA2 carriers, the breast cancer risk varied from 7.7% to 18.4% and prostate cancer risk from 34.1% to 87.6% between the ...
A recent prospective study estimated the lifetime risk of developing prostate cancer to be 29% for BRCA1 and 60% for BRCA2 carriers (5). The risks of developing ...
Apr 27, 2017 ˇ BRCA1/2 mutations increase the risk of breast and prostate cancer in men. Common genetic variants modify cancer risks for female carriers of ...
Jul 28, 2021 ˇ Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic. Variant Carriers Using Polygenic Risk Scores. Daniel R. Barnes. , PhD,1 ...
Aug 15, 2024 ˇ PRSPC was associated with prostate cancer risk for both BRCA1 (OR = 1.73, 95% CI = 1.28-2.33) and BRCA2 (OR = 1.60, 95% CI = 1.34-1.91) carriers ...
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... variants modify cancer risks for female carriers of BRCA1/2 ... Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores.
Missing: Pathogenic Variant
Dec 28, 2021 ˇ BRCA1 and BRCA2 pathogenic variants (PVs) are associated with prostate cancer (PCa) risk, but a wide range of relative risks (RRs) has been reported.
Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores ; 14 ˇ Journal of the National Cancer Institute.
PCa risk for BRCA2 carriers increased with family history (HR per affected relative 1.68, 95% CI 0.99–2.85). BRCA2 mutations in the region bounded by positions ...
... variants on cancer risks for male carriers of BRCA1/2 ... Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores.