A method of perforating a membrane 10 is presented. The method comprises: bringing a membrane-denaturing substance into contact with or close proximity to at least a site of said membrane 10, said substance inducing a membrane-denaturing reaction by a stimulus; providing said stimulus to said substance...http://www.google.se/patents/US7320885?utm_source=gb-gplus-sharePatent US7320885 - Method of perforating membrane and apparatus therefor