WO2013148275A3 - System for delivering multiple ocular implants - Google Patents

System for delivering multiple ocular implants Download PDF

Info

Publication number
WO2013148275A3
WO2013148275A3 PCT/US2013/031636 US2013031636W WO2013148275A3 WO 2013148275 A3 WO2013148275 A3 WO 2013148275A3 US 2013031636 W US2013031636 W US 2013031636W WO 2013148275 A3 WO2013148275 A3 WO 2013148275A3
Authority
WO
WIPO (PCT)
Prior art keywords
implants
eye
ocular implants
delivery
delivering multiple
Prior art date
Application number
PCT/US2013/031636
Other languages
French (fr)
Other versions
WO2013148275A9 (en
WO2013148275A2 (en
Inventor
David Steven HAFFNER
Henrick K. Gille
Charles Raymond Kalina
John Joseph Cogger
Original Assignee
Glaukos Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaukos Corporation filed Critical Glaukos Corporation
Priority to EP13713303.9A priority Critical patent/EP2830553B1/en
Priority to EP17210154.5A priority patent/EP3342380A3/en
Priority to CA2868341A priority patent/CA2868341C/en
Priority to JP2015503312A priority patent/JP6465490B2/en
Priority to US14/387,657 priority patent/US9173775B2/en
Publication of WO2013148275A2 publication Critical patent/WO2013148275A2/en
Publication of WO2013148275A3 publication Critical patent/WO2013148275A3/en
Publication of WO2013148275A9 publication Critical patent/WO2013148275A9/en
Priority to US14/928,626 priority patent/US10271989B2/en
Priority to US16/396,211 priority patent/US11197780B2/en
Priority to US17/457,631 priority patent/US11944573B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/148—Implantation instruments specially adapted therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/009—Additional features; Implant or prostheses properties not otherwise provided for for single use, e.g. having means for preventing re-use
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2270/00—Control; Monitoring or safety arrangements
    • F04C2270/04—Force
    • F04C2270/042—Force radial
    • F04C2270/0421—Controlled or regulated

Abstract

Systems and methods for delivering multiple ocular implants to reduce intraocular pressure are disclosed. The ocular implants can be implanted at multiple sites within a single human eye without requiring removal of the delivery apparatus from the eye. A system for delivering multiple ocular implants can include at least two implants preloaded within a delivery device and configured to be implanted within the eye, a metering device configured to transfer energy to the implants for delivery at selected locations within the eye, wherein the metering device is configured to meter a variable amount of energy for each implant delivery event in the eye. The system can further include an injector mechanism configured to serially engage and drive each of the implants.
PCT/US2013/031636 2012-03-26 2013-03-14 System and method for delivering multiple ocular implants WO2013148275A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
EP13713303.9A EP2830553B1 (en) 2012-03-26 2013-03-14 Apparatus for delivering multiple ocular implants
EP17210154.5A EP3342380A3 (en) 2012-03-26 2013-03-14 System and method for delivering multiple ocular implants
CA2868341A CA2868341C (en) 2012-03-26 2013-03-14 System and method for delivering multiple ocular implants
JP2015503312A JP6465490B2 (en) 2012-03-26 2013-03-14 Implant delivery device
US14/387,657 US9173775B2 (en) 2012-03-26 2013-03-14 System for delivering multiple ocular implants
US14/928,626 US10271989B2 (en) 2012-03-26 2015-10-30 System and method for delivering multiple ocular implants
US16/396,211 US11197780B2 (en) 2012-03-26 2019-04-26 System and method for delivering multiple ocular implants
US17/457,631 US11944573B2 (en) 2012-03-26 2021-12-03 System and method for delivering multiple ocular implants

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261615479P 2012-03-26 2012-03-26
US61/615,479 2012-03-26

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US14/387,657 A-371-Of-International US9173775B2 (en) 2012-03-26 2013-03-14 System for delivering multiple ocular implants
US14/928,626 Continuation US10271989B2 (en) 2012-03-26 2015-10-30 System and method for delivering multiple ocular implants

Publications (3)

Publication Number Publication Date
WO2013148275A2 WO2013148275A2 (en) 2013-10-03
WO2013148275A3 true WO2013148275A3 (en) 2013-11-28
WO2013148275A9 WO2013148275A9 (en) 2014-09-25

Family

ID=48040441

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2013/031636 WO2013148275A2 (en) 2012-03-26 2013-03-14 System and method for delivering multiple ocular implants

Country Status (6)

Country Link
US (5) US9173775B2 (en)
EP (2) EP2830553B1 (en)
JP (3) JP6465490B2 (en)
CA (2) CA3098762C (en)
HK (1) HK1257538A1 (en)
WO (1) WO2013148275A2 (en)

Families Citing this family (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA01010832A (en) 1999-04-26 2003-06-30 Gmp Vision Solutions Inc Shunt device and method for treating glaucoma.
US7867186B2 (en) 2002-04-08 2011-01-11 Glaukos Corporation Devices and methods for treatment of ocular disorders
US6638239B1 (en) 2000-04-14 2003-10-28 Glaukos Corporation Apparatus and method for treating glaucoma
EP1977724A1 (en) 2001-04-07 2008-10-08 Glaukos Corporation System for treating ocular disorders
US7431710B2 (en) 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
US7331984B2 (en) 2001-08-28 2008-02-19 Glaukos Corporation Glaucoma stent for treating glaucoma and methods of use
US7909789B2 (en) 2006-06-26 2011-03-22 Sight Sciences, Inc. Intraocular implants and methods and kits therefor
US10085884B2 (en) 2006-06-30 2018-10-02 Aquesys, Inc. Intraocular devices
US8852256B2 (en) 2010-11-15 2014-10-07 Aquesys, Inc. Methods for intraocular shunt placement
US8663303B2 (en) 2010-11-15 2014-03-04 Aquesys, Inc. Methods for deploying an intraocular shunt from a deployment device and into an eye
US20120123316A1 (en) 2010-11-15 2012-05-17 Aquesys, Inc. Intraocular shunts for placement in the intra-tenon's space
US8721702B2 (en) 2010-11-15 2014-05-13 Aquesys, Inc. Intraocular shunt deployment devices
CA2668954C (en) 2006-11-10 2020-09-08 Glaukos Corporation Uveoscleral shunt and methods for implanting same
US20170360609A9 (en) 2007-09-24 2017-12-21 Ivantis, Inc. Methods and devices for increasing aqueous humor outflow
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
WO2011097408A1 (en) 2010-02-05 2011-08-11 Sight Sciences, Inc Intraocular implants and related kits and methods
US20160256317A1 (en) 2010-11-15 2016-09-08 Aquesys, Inc. Methods for implanting intraocular shunts
US10080682B2 (en) 2011-12-08 2018-09-25 Aquesys, Inc. Intrascleral shunt placement
US8765210B2 (en) 2011-12-08 2014-07-01 Aquesys, Inc. Systems and methods for making gelatin shunts
US9610195B2 (en) 2013-02-27 2017-04-04 Aquesys, Inc. Intraocular shunt implantation methods and devices
US9808373B2 (en) 2013-06-28 2017-11-07 Aquesys, Inc. Intraocular shunt implantation
US8852136B2 (en) 2011-12-08 2014-10-07 Aquesys, Inc. Methods for placing a shunt into the intra-scleral space
EP2844200B1 (en) 2012-03-20 2020-11-25 Sight Sciences, Inc Ocular delivery systems
WO2013148275A2 (en) 2012-03-26 2013-10-03 Glaukos Corporation System and method for delivering multiple ocular implants
US9358156B2 (en) 2012-04-18 2016-06-07 Invantis, Inc. Ocular implants for delivery into an anterior chamber of the eye
US10617558B2 (en) 2012-11-28 2020-04-14 Ivantis, Inc. Apparatus for delivering ocular implants into an anterior chamber of the eye
US9125723B2 (en) 2013-02-19 2015-09-08 Aquesys, Inc. Adjustable glaucoma implant
US10159600B2 (en) 2013-02-19 2018-12-25 Aquesys, Inc. Adjustable intraocular flow regulation
US9592151B2 (en) 2013-03-15 2017-03-14 Glaukos Corporation Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye
US10517759B2 (en) 2013-03-15 2019-12-31 Glaukos Corporation Glaucoma stent and methods thereof for glaucoma treatment
WO2014145021A1 (en) * 2013-03-15 2014-09-18 Orange County Glaucoma, Pc Enhancement of aqueous flow
US9585790B2 (en) 2013-11-14 2017-03-07 Aquesys, Inc. Intraocular shunt inserter
JP6546194B2 (en) * 2013-12-06 2019-07-17 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ Anterior chamber implant for treating ocular conditions
RU2728195C2 (en) * 2014-02-26 2020-07-28 Аллерган, Инк. Device for delivery of intraocular implant and methods of its use
US20170172438A1 (en) * 2014-04-04 2017-06-22 President And Fellows Of Harvard College Systems and methods for injectable devices
WO2015184173A1 (en) 2014-05-29 2015-12-03 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
JP2017136098A (en) * 2014-06-10 2017-08-10 公立大学法人和歌山県立医科大学 Glaucoma implant detention tool
WO2016004223A1 (en) 2014-07-01 2016-01-07 Cao Ariel Methods and devices for implantation of intraocular pressure sensors
JP2017527329A (en) * 2014-07-01 2017-09-21 インジェクトセンス， インコーポレイテッド Hermetic sealed implant sensor with vertical stacking structure
WO2016011056A1 (en) 2014-07-14 2016-01-21 Ivantis, Inc. Ocular implant delivery system and method
US9999542B2 (en) * 2014-07-16 2018-06-19 Doheny Eye Institute Systems, methods, and devices for cannula insertion
DE102014221373A1 (en) * 2014-10-21 2016-04-21 Implandata Ophthalmic Products Gmbh Combined eye implant
AU2016230026B2 (en) * 2015-03-06 2020-07-09 Envisia Therapeutics, Inc. Implant applicators and methods of administering implants
AU2016235432B2 (en) 2015-03-20 2020-02-27 Glaukos Corporation Gonioscopic devices
US10111775B2 (en) * 2015-03-20 2018-10-30 1039578 B.C. Ltd Applicator for superficial corneal medicaments
CN107530190B (en) * 2015-03-31 2021-03-02 美国商业眼科医疗器械公司 Ophthalmic delivery systems and methods
US10299958B2 (en) 2015-03-31 2019-05-28 Sight Sciences, Inc. Ocular delivery systems and methods
BR112017025859A2 (en) 2015-06-03 2018-08-14 Aquesys, Inc. external ab intraocular shunt placement
CN108883070A (en) 2015-07-23 2018-11-23 爱瑞制药公司 For treating the intravitreal drug delivery system of eye disease
CN108135470B (en) 2015-08-14 2021-03-09 伊万提斯公司 Ocular implant with pressure sensor and delivery system
WO2017040853A1 (en) 2015-09-02 2017-03-09 Glaukos Corporation Drug delivery implants with bi-directional delivery capacity
WO2017049248A1 (en) 2015-09-16 2017-03-23 Orange County Glaucoma, Pc Shunt for vascular flow enhancement
US11564833B2 (en) 2015-09-25 2023-01-31 Glaukos Corporation Punctal implants with controlled drug delivery features and methods of using same
WO2017106517A1 (en) 2015-12-15 2017-06-22 Ivantis, Inc. Ocular implant and delivery system
US11382657B2 (en) 2016-02-18 2022-07-12 Synergetics Usa, Inc. Surgical devices with triggered propulsion system for inserting a trocar-cannula assembly
US10485577B2 (en) 2016-02-18 2019-11-26 Synergetics Usa, Inc. Surgical device with triggered propulsion system for inserting a trocar-cannula assembly
GB2551102A (en) * 2016-04-04 2017-12-13 Gerard Rohan Jayamanne Don System and method for image guided insertion of intraocular devices for control of Intraocular pressure and other intraocular diagnostic and interventional
WO2017184881A1 (en) 2016-04-20 2017-10-26 Harold Alexander Heitzmann Bioresorbable ocular drug delivery device
CN114532976A (en) 2016-05-31 2022-05-27 酷拉公司 Implantable intraocular pressure sensor and method of use
WO2017210627A1 (en) 2016-06-02 2017-12-07 Aquesys, Inc. Intraocular drug delivery
US10674906B2 (en) 2017-02-24 2020-06-09 Glaukos Corporation Gonioscopes
GB201705177D0 (en) * 2017-03-31 2017-05-17 Sharma Anant Device to aid movement of substance from the eye
JP6930874B2 (en) * 2017-07-31 2021-09-01 マニー株式会社 Cannula holder
WO2019028138A1 (en) * 2017-08-01 2019-02-07 Duke University Self-deploying injector for implants and methods of making and using same
US10835419B2 (en) * 2017-08-17 2020-11-17 Aspip Inc. Method, device and system for treatment of elevated intraocular pressure
US11116625B2 (en) 2017-09-28 2021-09-14 Glaukos Corporation Apparatus and method for controlling placement of intraocular implants
JP7457648B2 (en) 2017-09-29 2024-03-28 グローコス コーポレーション Intraocular physiological sensors
US11376040B2 (en) 2017-10-06 2022-07-05 Glaukos Corporation Systems and methods for delivering multiple ocular implants
US11576816B2 (en) * 2017-10-18 2023-02-14 Jesus Moreno Opthalmic microsurgical instrument
USD846738S1 (en) * 2017-10-27 2019-04-23 Glaukos Corporation Implant delivery apparatus
US11246753B2 (en) 2017-11-08 2022-02-15 Aquesys, Inc. Manually adjustable intraocular flow regulation
CA3091154C (en) * 2018-02-22 2023-10-03 Ivantis, Inc. Ocular implant and delivery system
US10952898B2 (en) 2018-03-09 2021-03-23 Aquesys, Inc. Intraocular shunt inserter
US11135089B2 (en) 2018-03-09 2021-10-05 Aquesys, Inc. Intraocular shunt inserter
US10258517B1 (en) 2018-05-25 2019-04-16 Tredegar Film Products Corporation Fluid distribution material for absorbent articles
US10722397B2 (en) 2018-10-24 2020-07-28 New World Medical, Inc. Ophthalmic device
JP2022505778A (en) 2018-10-24 2022-01-14 ニュー ワールド メディカル インコーポレイテッド Ophthalmic device
US11273285B2 (en) 2019-02-07 2022-03-15 DePuy Synthes Products, Inc. Ancillary device for detaching implants
JP1654731S (en) * 2019-02-15 2020-03-09
USD959659S1 (en) * 2019-05-10 2022-08-02 DePuy Synthes Products, Inc. Implant release handle
EP3993743A4 (en) 2019-07-01 2023-07-26 Michael S. Berlin Image guidance methods and apparatus for glaucoma surgery
CN110584874B (en) * 2019-08-26 2022-05-06 江苏百视通医疗器械有限公司 Implant conveying device
CN110693647B (en) * 2019-08-26 2022-01-18 江苏百视通医疗器械有限公司 Implant conveying device
CN110507476B (en) * 2019-09-12 2021-10-26 格劳科斯公司 Method of making an ocular implant delivery device
US11504270B1 (en) 2019-09-27 2022-11-22 Sight Sciences, Inc. Ocular delivery systems and methods
US11464914B2 (en) * 2019-10-21 2022-10-11 Ripple Therapeutics Corporation Intravitreal injector
JP6925464B1 (en) * 2020-02-21 2021-08-25 巨晰光纖股▲ふん▼有限公司 Bioactive glass shunt with drug carrier function
DE102020002231B4 (en) 2020-04-09 2022-02-17 aixtent GmbH Method of manufacturing an implant for insertion into Schlemm's canal of an eye, implant and arrangement with an implant
CN112915012A (en) * 2020-09-10 2021-06-08 美蓝(杭州)医药科技有限公司 Dispensing syringe and method of use thereof
CN215875548U (en) * 2020-09-10 2022-02-22 美蓝(杭州)医药科技有限公司 Integrated medicine dispensing injector with external vent grooves
JP7220688B2 (en) * 2020-09-16 2023-02-10 巨晰光纖股▲ふん▼有限公司 Diversion support frame for eyeball drainage
JP2024503989A (en) 2021-01-11 2024-01-30 アルコン インコーポレイティド Systems and methods for viscoelastic delivery
WO2022236779A1 (en) * 2021-05-13 2022-11-17 Beijing Sightnovo Medical Technology Co., Ltd Medical penetration and drainage for glaucoma treatment
KR20240026984A (en) * 2021-07-07 2024-02-29 제넨테크, 인크. Rod inserter system and method
USD1018842S1 (en) 2021-11-24 2024-03-19 Iantrek, Inc. Cannula assembly for an ocular implant delivery device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050271704A1 (en) * 2002-04-08 2005-12-08 Hosheng Tu Injectable glaucoma implants with multiple openings
WO2008061043A2 (en) * 2006-11-10 2008-05-22 Glaukos Corporation Uveoscleral shunt and methods for implanting same
WO2010093945A2 (en) * 2009-02-13 2010-08-19 Glaukos Corporation Uveoscleral drug delivery implant and methods for implanting the same
US20110112546A1 (en) * 2009-07-29 2011-05-12 Juan Jr Eugene De Ocular implant applier and methods of use

Family Cites Families (664)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2031754A (en) 1932-11-04 1936-02-25 Ernest J Sweetland Extensible coupling
US2127903A (en) 1936-05-05 1938-08-23 Davis & Geck Inc Tube for surgical purposes and method of preparing and using the same
US2269963A (en) * 1940-06-01 1942-01-13 Wappler Frederick Charles Implanting device
US3159161A (en) 1962-11-14 1964-12-01 Ness Richard Alton Fistulizing canaliculus
US3416530A (en) 1966-03-02 1968-12-17 Richard A. Ness Eyeball medication dispensing tablet
US3439675A (en) 1966-06-14 1969-04-22 Becton Dickinson Co Deformable needle assembly
US3915172A (en) 1970-05-27 1975-10-28 Ceskoslovenska Akademie Ved Capillary drain for glaucoma
US3717151A (en) 1971-03-11 1973-02-20 R Collett Flesh penetrating apparatus
US3788327A (en) 1971-03-30 1974-01-29 H Donowitz Surgical implant device
SE353590B (en) 1971-10-01 1973-02-05 J Kaller
US3948871A (en) 1972-04-21 1976-04-06 George H. Butterfield And Son Composition for hard type contact lens with wettable surface
US3863623A (en) 1972-06-19 1975-02-04 Medical College Of Georgia Fou Method for microscintigraphic evaluation studies
US3948271A (en) 1972-11-07 1976-04-06 Taichiro Akiyama Drain for the eardrum and apparatus for introducing the same
US3976077A (en) 1975-02-03 1976-08-24 Kerfoot Jr Franklin W Eye surgery device
US4037604A (en) 1976-01-05 1977-07-26 Newkirk John B Artifical biological drainage device
US4043346A (en) 1976-03-10 1977-08-23 Baylor College Of Medicine Catheter
FR2349469A1 (en) 1976-04-30 1977-11-25 Ferlor Vehicle sun roof operating device - has handle on cross-brace between two arms pivoted to brackets screwed to sun roof surround
US4168697A (en) 1977-01-17 1979-09-25 Cantekin Erdem I Middle ear ventilating tube and method
US4113088A (en) 1977-06-06 1978-09-12 Binkhorst Richard D Sterile package
US4175563A (en) 1977-10-05 1979-11-27 Arenberg Irving K Biological drainage shunt
US4299227A (en) 1979-10-19 1981-11-10 Lincoff Harvey A Ophthalmological appliance
US4402681A (en) 1980-08-23 1983-09-06 Haas Joseph S Artificial implant valve for the regulation of intraocular pressure
US4366582A (en) 1980-12-01 1983-01-04 Faulkner Gerald D Posterior chamber intraocular lens
NO147900C (en) 1981-03-12 1983-07-06 Finn Skjaerpe MICROSURGICAL INSTRUMENT.
US4457757A (en) 1981-07-20 1984-07-03 Molteno Anthony C B Device for draining aqueous humour
US4428746A (en) 1981-07-29 1984-01-31 Antonio Mendez Glaucoma treatment device
US4449529A (en) 1981-11-18 1984-05-22 Becton Dickinson And Company Automatic retractable lancet assembly
DE3206834A1 (en) 1982-02-26 1983-09-15 Walter Dr. 4000 Düsseldorf Messingschlager DRAINAGE TUBE FOR USE IN AN OPERATIONAL ACCESS TO A BODY RECOVERY
US4554918A (en) 1982-07-28 1985-11-26 White Thomas C Ocular pressure relief device
US4521210A (en) 1982-12-27 1985-06-04 Wong Vernon G Eye implant for relieving glaucoma, and device and method for use therewith
US4560383A (en) 1983-10-27 1985-12-24 Leiske Larry G Anterior chamber intraocular lens
US4578058A (en) 1984-04-02 1986-03-25 Grandon Stanley C Intraocular catheter apparatus and method of use
US4787885A (en) 1984-04-06 1988-11-29 Binder Perry S Hydrogel seton
US4634418A (en) 1984-04-06 1987-01-06 Binder Perry S Hydrogel seton
DE3447642C1 (en) 1984-12-28 1986-09-18 Bernhard M. Dr. 5600 Wuppertal Cramer Steerable guidewire for catheters
US4604087A (en) 1985-02-26 1986-08-05 Joseph Neil H Aqueous humor drainage device
US4642090A (en) 1985-03-04 1987-02-10 Utrata Peter J Disposable combination scalpel blade and incision irrigator for ophthalmological use
US4820626A (en) 1985-06-06 1989-04-11 Thomas Jefferson University Method of treating a synthetic or naturally occuring surface with microvascular endothelial cells, and the treated surface itself
US4632842A (en) 1985-06-20 1986-12-30 Atrium Medical Corporation Glow discharge process for producing implantable devices
US4718907A (en) 1985-06-20 1988-01-12 Atrium Medical Corporation Vascular prosthesis having fluorinated coating with varying F/C ratio
US4733665C2 (en) 1985-11-07 2002-01-29 Expandable Grafts Partnership Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
US4692142A (en) 1986-02-24 1987-09-08 Dignam Bernard J Sutureless infusion cannula for ophthalmic surgery
NZ215409A (en) 1986-03-07 1989-02-24 Anthony Christopher Be Molteno Implant for drainage of aqueous humour in glaucoma
CH670760A5 (en) 1986-06-02 1989-07-14 Sulzer Ag
US4722724A (en) 1986-06-23 1988-02-02 Stanley Schocket Anterior chamber tube shunt to an encircling band, and related surgical procedure
US4826478A (en) 1986-06-23 1989-05-02 Stanley Schocket Anterior chamber tube shunt to an encircling band, and related surgical procedure
US4867173A (en) 1986-06-30 1989-09-19 Meadox Surgimed A/S Steerable guidewire
US4782819A (en) 1987-02-25 1988-11-08 Adair Edwin Lloyd Optical catheter
US4846793A (en) 1987-03-18 1989-07-11 Endocon, Inc. Injector for implanting multiple pellet medicaments
DE8717643U1 (en) 1987-05-12 1989-09-21 Foerster, Ernst, Dr.Med. Dr.Rer.Nat.
US4846172A (en) 1987-05-26 1989-07-11 Berlin Michael S Laser-delivery eye-treatment method
US4900300A (en) 1987-07-06 1990-02-13 Lee David A Surgical instrument
US4886488A (en) 1987-08-06 1989-12-12 White Thomas C Glaucoma drainage the lacrimal system and method
WO1989000869A1 (en) 1987-08-06 1989-02-09 White Thomas C Glaucoma drainage in the lacrimal system
WO1989001350A1 (en) 1987-08-19 1989-02-23 Olle Berg A drainage tube for sinus maxillaris, a means for its insertion and a means for making a hole for its positioning
US4870953A (en) 1987-11-13 1989-10-03 Donmicheal T Anthony Intravascular ultrasonic catheter/probe and method for treating intravascular blockage
US5053044A (en) 1988-01-11 1991-10-01 Devices For Vascular Intervention, Inc. Catheter and method for making intravascular incisions
US4800870A (en) 1988-03-11 1989-01-31 Reid Jr Ben A Method and apparatus for bile duct exploration
US4936825A (en) 1988-04-11 1990-06-26 Ungerleider Bruce A Method for reducing intraocular pressure caused by glaucoma
US5005577A (en) 1988-08-23 1991-04-09 Frenkel Ronald E P Intraocular lens pressure monitoring device
DE68922497T2 (en) 1988-08-24 1995-09-14 Marvin J Slepian ENDOLUMINAL SEAL WITH BISDEGRADABLE POLYMERS.
US5681275A (en) 1988-10-07 1997-10-28 Ahmed; Abdul Mateen Ophthalmological device with adaptable multiple distribution plates
US5785674A (en) 1988-10-07 1998-07-28 Mateen; Ahmed Abdul Device and method for treating glaucoma
US5116327A (en) 1989-06-05 1992-05-26 Helix Medical, Inc. Hysterectomy drain appliance
US4991602A (en) 1989-06-27 1991-02-12 Flexmedics Corporation Flexible guide wire with safety tip
SG49267A1 (en) 1989-08-14 1998-05-18 Photogenesis Inc Surgical instrument and cell isolation and transplantation
US5817075A (en) 1989-08-14 1998-10-06 Photogenesis, Inc. Method for preparation and transplantation of planar implants and surgical instrument therefor
US4986810A (en) 1989-09-01 1991-01-22 Neal Semrad Toggle catheter
US5169386A (en) 1989-09-11 1992-12-08 Bruce B. Becker Method and catheter for dilatation of the lacrimal system
FR2651668B1 (en) 1989-09-12 1991-12-27 Leon Claude MICROSCOPE-ENDOSCOPE ASSEMBLY USEFUL IN PARTICULAR IN SURGERY.
US5053040A (en) 1989-11-09 1991-10-01 Goldsmith Iii Manning M Method of performing a myringotomy
US4946436A (en) 1989-11-17 1990-08-07 Smith Stewart G Pressure-relieving device and process for implanting
USRE35390E (en) 1989-11-17 1996-12-03 Smith; Stewart G. Pressure relieving device and process for implanting
US5092837A (en) 1989-12-20 1992-03-03 Robert Ritch Method for the treatment of glaucoma
US4968296A (en) 1989-12-20 1990-11-06 Robert Ritch Transscleral drainage implant device for the treatment of glaucoma
DE4030004A1 (en) 1990-01-05 1992-03-26 Heino Dr Hermeking INSTRUMENT WITH HOOK PLATE FOR IMPLANTING AN ARTIFICIAL LENS
US5221255A (en) 1990-01-10 1993-06-22 Mahurkar Sakharam D Reinforced multiple lumen catheter
US5073163A (en) 1990-01-29 1991-12-17 Lippman Myron E Apparatus for treating glaucoma
US5180362A (en) 1990-04-03 1993-01-19 Worst J G F Gonio seton
US5129895A (en) 1990-05-16 1992-07-14 Sunrise Technologies, Inc. Laser sclerostomy procedure
US5041081A (en) 1990-05-18 1991-08-20 Odrich Ronald B Ocular implant for controlling glaucoma
US5127901A (en) 1990-05-18 1992-07-07 Odrich Ronald B Implant with subconjunctival arch
US5476445A (en) 1990-05-31 1995-12-19 Iovision, Inc. Glaucoma implant with a temporary flow restricting seal
US5397300A (en) 1990-05-31 1995-03-14 Iovision, Inc. Glaucoma implant
US5178604A (en) 1990-05-31 1993-01-12 Iovision, Inc. Glaucoma implant
WO1992000112A1 (en) 1990-06-25 1992-01-09 Ungerleider Bruce A Apparatus for reducing intraocular pressure
US5725529A (en) 1990-09-25 1998-03-10 Innovasive Devices, Inc. Bone fastener
US5688261A (en) 1990-11-07 1997-11-18 Premier Laser Systems, Inc. Transparent laser surgical probe
US5273530A (en) 1990-11-14 1993-12-28 The University Of Rochester Intraretinal delivery and withdrawal instruments
US5454796A (en) 1991-04-09 1995-10-03 Hood Laboratories Device and method for controlling intraocular fluid pressure
US5312394A (en) 1991-04-29 1994-05-17 Hugh Beckman Apparatus and method for surgically performing a filtering operation on an eye for glaucoma
US5246451A (en) 1991-04-30 1993-09-21 Medtronic, Inc. Vascular prosthesis and method
US5358492A (en) 1991-05-02 1994-10-25 Feibus Miriam H Woven surgical drain and method of making
US6007511A (en) 1991-05-08 1999-12-28 Prywes; Arnold S. Shunt valve and therapeutic delivery system for treatment of glaucoma and methods and apparatus for its installation
US5300020A (en) 1991-05-31 1994-04-05 Medflex Corporation Surgically implantable device for glaucoma relief
US5171213A (en) 1991-08-14 1992-12-15 Price Jr Francis W Technique for fistulization of the eye and an eye filtration prosthesis useful therefor
US5326345A (en) 1991-08-14 1994-07-05 Price Jr Francis W Eye filtration prostheses
US5500013A (en) 1991-10-04 1996-03-19 Scimed Life Systems, Inc. Biodegradable drug delivery vascular stent
GB2260585A (en) 1991-10-09 1993-04-21 Avdel Systems Ltd Self-plugging blind rivet
US5290310A (en) 1991-10-30 1994-03-01 Howmedica, Inc. Hemostatic implant introducer
US5360399A (en) 1992-01-10 1994-11-01 Robert Stegmann Method and apparatus for maintaining the normal intraocular pressure
US5207685A (en) 1992-02-11 1993-05-04 Cinberg James Z Tympanic ventilation tube and related technique
US5334137A (en) 1992-02-21 1994-08-02 Eagle Vision, Inc. Lacrimal fluid control device
US5346464A (en) 1992-03-10 1994-09-13 Camras Carl B Method and apparatus for reducing intraocular pressure
US5284476A (en) 1992-03-20 1994-02-08 Koch Paul S Nuclear hydrolysis cannula
US5415666A (en) 1992-03-23 1995-05-16 Advanced Surgical, Inc. Tethered clamp retractor
US5368601A (en) 1992-04-30 1994-11-29 Lasersurge, Inc. Trocar wound closure device
US5370641A (en) 1992-05-22 1994-12-06 O'donnell, Jr.; Francis E. Laser trabeculodissection
US5290295A (en) 1992-07-15 1994-03-01 Querals & Fine, Inc. Insertion tool for an intraluminal graft procedure
WO1994002081A1 (en) 1992-07-16 1994-02-03 Wong Vernon G Eye implant suitable for relief of glaucoma
JP3739411B2 (en) 1992-09-08 2006-01-25 敬二 伊垣 Vascular stent, manufacturing method thereof, and vascular stent device
US5318513A (en) 1992-09-24 1994-06-07 Leib Martin L Canalicular balloon fixation stent
US5370607A (en) 1992-10-28 1994-12-06 Annuit Coeptis, Inc. Glaucoma implant device and method for implanting same
WO1994013234A1 (en) 1992-12-17 1994-06-23 Michael Andrew Coote Implant device and method for treatment of glaucoma
US5338291A (en) 1993-02-03 1994-08-16 Pudenz-Schulte Medical Research Corporation Glaucoma shunt and method for draining aqueous humor
US5423330A (en) 1993-03-10 1995-06-13 The University Of Miami Capsule suction punch instrument and method of use
US5342370A (en) 1993-03-19 1994-08-30 University Of Miami Method and apparatus for implanting an artifical meshwork in glaucoma surgery
IL105828A (en) 1993-05-28 1999-06-20 Medinol Ltd Medical stent
US5653724A (en) 1993-08-18 1997-08-05 Imonti; Maurice M. Angled phacoemulsifier tip
US5735892A (en) 1993-08-18 1998-04-07 W. L. Gore & Associates, Inc. Intraluminal stent graft
FR2710269A1 (en) 1993-09-22 1995-03-31 Voir Vivre Implantable device for the treatment of edemas.
FI934513A (en) 1993-10-13 1995-04-14 Leiras Oy Anordning Foer injection with implant
US5639278A (en) 1993-10-21 1997-06-17 Corvita Corporation Expandable supportive bifurcated endoluminal grafts
US5695479A (en) 1993-11-01 1997-12-09 Jagpal; Ravindar Instrument, system, kit and method for catheterization procedures
US5479222A (en) 1993-11-15 1995-12-26 Volk; Donald A. Indirect ophthalmoscopy lens system and adapter lenses
US5445637A (en) 1993-12-06 1995-08-29 American Cyanamid Company Method and apparatus for preventing posterior capsular opacification
US5817100A (en) 1994-02-07 1998-10-06 Kabushikikaisya Igaki Iryo Sekkei Stent device and stent supplying system
US5743868A (en) 1994-02-14 1998-04-28 Brown; Reay H. Corneal pressure-regulating implant device
US6135977A (en) 1994-02-16 2000-10-24 Possis Medical, Inc. Rheolytic catheter
US6165210A (en) 1994-04-01 2000-12-26 Gore Enterprise Holdings, Inc. Self-expandable helical intravascular stent and stent-graft
US5716394A (en) 1994-04-29 1998-02-10 W. L. Gore & Associates, Inc. Blood contact surfaces using extracellular matrix synthesized in vitro
IL109499A (en) 1994-05-02 1998-01-04 Univ Ramot Implant device for draining excess intraocular fluid
FR2721499B1 (en) 1994-06-22 1997-01-03 Opsia Trabeculectomy implant.
US5725546A (en) 1994-06-24 1998-03-10 Target Therapeutics, Inc. Detachable microcoil delivery catheter
US6405732B1 (en) 1994-06-24 2002-06-18 Curon Medical, Inc. Method to treat gastric reflux via the detection and ablation of gastro-esophageal nerves and receptors
US5704907A (en) 1994-07-22 1998-01-06 Wound Healing Of Oklahoma Method and apparatus for lowering the intraocular pressure of an eye
US6102045A (en) 1994-07-22 2000-08-15 Premier Laser Systems, Inc. Method and apparatus for lowering the intraocular pressure of an eye
US5520631A (en) 1994-07-22 1996-05-28 Wound Healing Of Oklahoma Method and apparatus for lowering the intraocular pressure of an eye
US5462558A (en) * 1994-08-29 1995-10-31 United States Surgical Corporation Suture clip applier
US5702419A (en) 1994-09-21 1997-12-30 Wake Forest University Expandable, intraluminal stents
US5643321A (en) 1994-11-10 1997-07-01 Innovasive Devices Suture anchor assembly and methods
US5601094A (en) 1994-11-22 1997-02-11 Reiss; George R. Ophthalmic shunt
US5433701A (en) 1994-12-21 1995-07-18 Rubinstein; Mark H. Apparatus for reducing ocular pressure
US5891084A (en) 1994-12-27 1999-04-06 Lee; Vincent W. Multiple chamber catheter delivery system
US5556400A (en) 1994-12-27 1996-09-17 Tunis; Scott W. Methods of preparing and inserting flexible intraocular lenses and a configuration for flexible intraocular lenses
US5558630A (en) 1994-12-30 1996-09-24 Fisher; Bret L. Intrascleral implant and method for the regulation of intraocular pressure
GB2296663A (en) 1995-01-03 1996-07-10 Ahmed Salih Mahmud Drainage device for alleviating excess ophthalmic fluid pressure
US5792099A (en) 1995-02-14 1998-08-11 Decamp; Dennis Syringe and cannula for insertion of viscoelastic material into an eye and method of using same
BE1009278A3 (en) 1995-04-12 1997-01-07 Corvita Europ Guardian self-expandable medical device introduced in cavite body, and medical device with a stake as.
US5626558A (en) 1995-05-05 1997-05-06 Suson; John Adjustable flow rate glaucoma shunt and method of using same
US5968058A (en) 1996-03-27 1999-10-19 Optonol Ltd. Device for and method of implanting an intraocular implant
IL113723A (en) 1995-05-14 2002-11-10 Optonol Ltd Intraocular implant
CN1124164C (en) 1995-05-14 2003-10-15 奥普通诺尔有限公司 Intraocular implant, delivery device, and method of implantation
WO1996037167A1 (en) 1995-05-25 1996-11-28 Raychem Corporation Stent assembly
US5723005A (en) 1995-06-07 1998-03-03 Herrick Family Limited Partnership Punctum plug having a collapsible flared section and method
US6033434A (en) 1995-06-08 2000-03-07 Ave Galway Limited Bifurcated endovascular stent and methods for forming and placing
US5913852A (en) 1995-07-21 1999-06-22 Nemours Foundation Drain cannula
US5934285A (en) 1995-07-27 1999-08-10 Michiel S. Kritzinger Method for reducing irregular astigmatism and debris/epithelium in the interface during lamellar corneal flap/cap surgery
US5766243A (en) 1995-08-21 1998-06-16 Oasis Medical, Inc. Abrasive polished canalicular implant
US5662600A (en) 1995-09-29 1997-09-02 Pudenz-Schulte Medical Research Corporation Burr-hole flow control device
US6099558A (en) 1995-10-10 2000-08-08 Edwards Lifesciences Corp. Intraluminal grafting of a bifuricated artery
US5836939A (en) 1995-10-25 1998-11-17 Plc Medical Systems, Inc. Surgical laser handpiece
US5741292A (en) 1995-10-26 1998-04-21 Eagle Vision Punctum dilating and plug inserting instrument with push-button plug release
US5651783A (en) 1995-12-20 1997-07-29 Reynard; Michael Fiber optic sleeve for surgical instruments
US5741282A (en) 1996-01-22 1998-04-21 The Anspach Effort, Inc. Soft tissue fastener device
US5722948A (en) 1996-02-14 1998-03-03 Gross; Fredric J. Covering for an ocular device
US5807302A (en) 1996-04-01 1998-09-15 Wandel; Thaddeus Treatment of glaucoma
US6629981B2 (en) 2000-07-06 2003-10-07 Endocare, Inc. Stent delivery system
US5830179A (en) 1996-04-09 1998-11-03 Endocare, Inc. Urological stent therapy system and method
US5865831A (en) 1996-04-17 1999-02-02 Premier Laser Systems, Inc. Laser surgical procedures for treatment of glaucoma
NL1002898C2 (en) 1996-04-18 1997-10-21 Cordis Europ Catheter with marker sleeve.
US5932299A (en) 1996-04-23 1999-08-03 Katoot; Mohammad W. Method for modifying the surface of an object
US6530896B1 (en) 1996-05-13 2003-03-11 James B. Elliott Apparatus and method for introducing an implant
US5669501A (en) 1996-06-05 1997-09-23 Xomed Surgical Products, Inc. Package and method for delivering a medical implant
US5833643A (en) * 1996-06-07 1998-11-10 Scieran Technologies, Inc. Apparatus for performing ophthalmic procedures
US5681323A (en) 1996-07-15 1997-10-28 Arick; Daniel S. Emergency cricothyrotomy tube insertion
US5755682A (en) 1996-08-13 1998-05-26 Heartstent Corporation Method and apparatus for performing coronary artery bypass surgery
US5655548A (en) 1996-09-16 1997-08-12 Circulation, Inc. Method for treatment of ischemic heart disease by providing transvenous myocardial perfusion
RU2143250C1 (en) 1996-09-25 1999-12-27 Астахов Сергей Юрьевич Method for treating patients suffering from a combination of glaucoma and cataract
US5733256A (en) 1996-09-26 1998-03-31 Micro Medical Devices Integrated phacoemulsification system
US6007510A (en) 1996-10-25 1999-12-28 Anamed, Inc. Implantable devices and methods for controlling the flow of fluids within the body
US6881197B1 (en) 1996-10-25 2005-04-19 Anamed, Inc. Sutureless implantable device and method for treatment of glaucoma
US5807244A (en) 1996-11-15 1998-09-15 Barot; Jagdish Shantilal Single use disposable iris retractor
US5941250A (en) 1996-11-21 1999-08-24 University Of Louisville Research Foundation Inc. Retinal tissue implantation method
AUPO394496A0 (en) 1996-11-29 1997-01-02 Lions Eye Institute Biological microfistula tube and implantation method and apparatus
FR2757068B1 (en) 1996-12-13 1999-04-23 Jussmann Alberto SELF-FIXING DRAIN
DE19651951C2 (en) 1996-12-16 2002-06-27 Adeva Medical Ges Fuer Entwick Shunt valve
US6261256B1 (en) 1996-12-20 2001-07-17 Abdul Mateen Ahmed Pocket medical valve & method
US5713844A (en) 1997-01-10 1998-02-03 Peyman; Gholam A. Device and method for regulating intraocular pressure
GB9700390D0 (en) 1997-01-10 1997-02-26 Biocompatibles Ltd Device for use in the eye
US6780165B2 (en) 1997-01-22 2004-08-24 Advanced Medical Optics Micro-burst ultrasonic power delivery
DE19705815C2 (en) 1997-02-15 1999-02-11 Heidelberg Engineering Optisch Medical device for microsurgery on the eye
FR2759577B1 (en) 1997-02-17 1999-08-06 Corneal Ind DEEP SCLERECTOMY IMPLANT
US6071286A (en) 1997-02-19 2000-06-06 Mawad; Michel E. Combination angioplasty balloon/stent deployment device
US5893837A (en) 1997-02-28 1999-04-13 Staar Surgical Company, Inc. Glaucoma drain implanting device and method
US5882327A (en) 1997-04-17 1999-03-16 Jacob; Jean T. Long-term glaucoma drainage implant
US6050970A (en) 1997-05-08 2000-04-18 Pharmacia & Upjohn Company Method and apparatus for inserting a glaucoma implant in an anterior and posterior segment of the eye
US5752928A (en) 1997-07-14 1998-05-19 Rdo Medical, Inc. Glaucoma pressure regulator
US5830171A (en) 1997-08-12 1998-11-03 Odyssey Medical, Inc. Punctal occluder
EP0898947A3 (en) 1997-08-15 1999-09-08 GRIESHABER & CO. AG SCHAFFHAUSEN Method and apparatus to improve the outflow of the aqueous humor of an eye
US6004302A (en) 1997-08-28 1999-12-21 Brierley; Lawrence A. Cannula
US6203513B1 (en) 1997-11-20 2001-03-20 Optonol Ltd. Flow regulating implant, method of manufacture, and delivery device
US8313454B2 (en) 1997-11-20 2012-11-20 Optonol Ltd. Fluid drainage device, delivery device, and associated methods of use and manufacture
US6036682A (en) 1997-12-02 2000-03-14 Scimed Life Systems, Inc. Catheter having a plurality of integral radiopaque bands
US6165209A (en) 1997-12-15 2000-12-26 Prolifix Medical, Inc. Vascular stent for reduction of restenosis
US5927585A (en) 1997-12-17 1999-07-27 Senco Products, Inc. Electric multiple impact fastener driving tool
US6050999A (en) * 1997-12-18 2000-04-18 Keravision, Inc. Corneal implant introducer and method of use
USD402757S (en) 1997-12-30 1998-12-15 Alza Corporation Implanter
US6682500B2 (en) 1998-01-29 2004-01-27 David Soltanpour Synthetic muscle based diaphragm pump apparatuses
US7780623B2 (en) 1998-01-29 2010-08-24 Soltanpour David P Implantable pump apparatuses
US6589198B1 (en) 1998-01-29 2003-07-08 David Soltanpour Implantable micro-pump assembly
US6168575B1 (en) 1998-01-29 2001-01-02 David Pyam Soltanpour Method and apparatus for controlling intraocular pressure
US6224570B1 (en) 1998-02-06 2001-05-01 Possis Medical, Inc. Rheolytic thrombectomy catheter and method of using same
US6030416A (en) 1998-02-13 2000-02-29 Pharmacia & Upjohn Ab Medical implants of stretch-crystallizable elastomers and methods of implantation
US6290684B1 (en) 1998-03-02 2001-09-18 Herrick Family Limited Partnership Punctum plug having a collapsible expanded section and distal tip extending substantially perpendicular thereto and method of inserting same
US6371960B2 (en) 1998-05-19 2002-04-16 Bausch & Lomb Surgical, Inc. Device for inserting a flexible intraocular lens
US6306114B1 (en) 1998-06-16 2001-10-23 Eagle Vision, Inc. Valved canalicular plug for lacrimal duct occlusion
US6077299A (en) 1998-06-22 2000-06-20 Eyetronic, Llc Non-invasively adjustable valve implant for the drainage of aqueous humor in glaucoma
US6319274B1 (en) 1998-06-22 2001-11-20 John H. Shadduck Devices and techniques for light-mediated stimulation of trabecular meshwork in glaucoma therapy
US6402734B1 (en) 1998-07-02 2002-06-11 Jeffrey N. Weiss Apparatus and method for cannulating retinal blood vessels
US6591838B2 (en) 1998-07-06 2003-07-15 Scimed Life Systems, Inc. Implant system and method for bulking tissue
US6309374B1 (en) 1998-08-03 2001-10-30 Insite Vision Incorporated Injection apparatus and method of using same
US6378526B1 (en) 1998-08-03 2002-04-30 Insite Vision, Incorporated Methods of ophthalmic administration
US6146387A (en) * 1998-08-26 2000-11-14 Linvatec Corporation Cannulated tissue anchor system
DE19840047B4 (en) 1998-09-02 2004-07-08 Neuhann, Thomas, Prof.Dr.med. Device for the targeted improvement and / or permanent guarantee of the permeability for eye chamber water through the trabecular mechanism in the Schlemm's Canal
US6290728B1 (en) 1998-09-10 2001-09-18 Percardia, Inc. Designs for left ventricular conduit
AU6384699A (en) 1998-09-10 2000-04-03 Percardia, Inc. Tmr shunt
US6264668B1 (en) 1998-09-16 2001-07-24 Arnold S. Prywes Ophthalmologic instrument for producing a fistula in the sclera
EP1447057A1 (en) 1998-09-30 2004-08-18 Bard Peripheral Vascular, Inc. Delivery mechanism for implantable stent
US6241721B1 (en) 1998-10-09 2001-06-05 Colette Cozean Laser surgical procedures for treatment of glaucoma
SE9803481D0 (en) 1998-10-13 1998-10-13 Pharmacia & Upjohn Ab Photocurable siloxane polymers
US6254612B1 (en) 1998-10-22 2001-07-03 Cordis Neurovascular, Inc. Hydraulic stent deployment system
GB9827415D0 (en) 1998-12-11 1999-02-03 Wild Andrew M Surgical apparatus and method for occluding a body passageway
US6454787B1 (en) 1998-12-11 2002-09-24 C. R. Bard, Inc. Collagen hemostatic foam
US6363938B2 (en) 1998-12-22 2002-04-02 Angiotrax, Inc. Methods and apparatus for perfusing tissue and/or stimulating revascularization and tissue growth
US6074395A (en) 1999-02-02 2000-06-13 Linvatec Corporation Cannulated tissue anchor insertion system
US6231597B1 (en) 1999-02-16 2001-05-15 Mark E. Deem Apparatus and methods for selectively stenting a portion of a vessel wall
MXPA01010832A (en) 1999-04-26 2003-06-30 Gmp Vision Solutions Inc Shunt device and method for treating glaucoma.
US20050119601A9 (en) 1999-04-26 2005-06-02 Lynch Mary G. Shunt device and method for treating glaucoma
US6699210B2 (en) 1999-04-27 2004-03-02 The Arizona Board Of Regents Glaucoma shunt and a method of making and surgically implanting the same
US6342058B1 (en) 1999-05-14 2002-01-29 Valdemar Portney Iris fixated intraocular lens and instrument for attaching same to an iris
US6558342B1 (en) 1999-06-02 2003-05-06 Optonol Ltd. Flow control device, introducer and method of implanting
US6306132B1 (en) 1999-06-17 2001-10-23 Vivant Medical Modular biopsy and microwave ablation needle delivery apparatus adapted to in situ assembly and method of use
US6221078B1 (en) 1999-06-25 2001-04-24 Stephen S. Bylsma Surgical implantation apparatus
US8550119B2 (en) 1999-06-28 2013-10-08 California Institute Of Technology Microfabricated elastomeric valve and pump systems
US7144616B1 (en) 1999-06-28 2006-12-05 California Institute Of Technology Microfabricated elastomeric valve and pump systems
US6899137B2 (en) 1999-06-28 2005-05-31 California Institute Of Technology Microfabricated elastomeric valve and pump systems
US20080277007A1 (en) 1999-06-28 2008-11-13 California Institute Of Technology Microfabricated elastomeric valve and pump systems
CA2721172C (en) 1999-06-28 2012-04-10 California Institute Of Technology Microfabricated elastomeric valve and pump systems
AU7066300A (en) 1999-08-23 2001-03-19 Conceptus, Inc. Insertion/deployment catheter system for intrafallopian contraception
US6605053B1 (en) 1999-09-10 2003-08-12 Percardia, Inc. Conduit designs and related methods for optimal flow control
US6187016B1 (en) 1999-09-14 2001-02-13 Daniel G. Hedges Stent retrieval device
US7758624B2 (en) 2000-11-13 2010-07-20 C. R. Bard, Inc. Implant delivery device
US6287313B1 (en) 1999-11-23 2001-09-11 Sdgi Holdings, Inc. Screw delivery system and method
AU776599B2 (en) 1999-11-24 2004-09-16 Grieshaber & Co. Ag Device for improving the aqueous humour outflow in the eye of a living thing
DE29920949U1 (en) 1999-11-29 2000-04-27 Bugge Mogens Suction tube for surgical purposes
KR100771149B1 (en) 1999-12-10 2007-10-30 아이싸이언스 인터벤셔날 코포레이션 Treatment of ocular disease
US6450937B1 (en) 1999-12-17 2002-09-17 C. R. Bard, Inc. Needle for implanting brachytherapy seeds
WO2001049227A1 (en) 2000-01-03 2001-07-12 Johns Hopkins University Surgical devices and methods of use thereof for enhanced tactile perception
US7217263B2 (en) 2000-01-03 2007-05-15 The Johns Hopkins University Device and method for manual retinal vein catheterization
US6726676B2 (en) 2000-01-05 2004-04-27 Grieshaber & Co. Ag Schaffhausen Method of and device for improving the flow of aqueous humor within the eye
US20030212383A1 (en) 2001-01-05 2003-11-13 Dana Cote System and methods for reducing intraocular pressure
US20050119737A1 (en) 2000-01-12 2005-06-02 Bene Eric A. Ocular implant and methods for making and using same
PL362931A1 (en) 2000-01-12 2004-11-02 Becton, Dickinson And Company Systems and methods for reducing intraocular pressure
US6589203B1 (en) 2000-01-26 2003-07-08 Peter Mitrev Glaucoma drainage device implant
US6375642B1 (en) 2000-02-15 2002-04-23 Grieshaber & Co. Ag Schaffhausen Method of and device for improving a drainage of aqueous humor within the eye
US6471666B1 (en) 2000-02-24 2002-10-29 Steven A. Odrich Injectable glaucoma device
US6623283B1 (en) 2000-03-08 2003-09-23 Autosplice, Inc. Connector with base having channels to facilitate surface mount solder attachment
US7077848B1 (en) 2000-03-11 2006-07-18 John Hopkins University Sutureless occular surgical methods and instruments for use in such methods
US20070031473A1 (en) 2005-08-05 2007-02-08 Peyman Gholam A Drug delivery system and method
US6613343B2 (en) 2000-04-12 2003-09-02 Pharmacia Groningen Bv Injectable intraocular accommodating lens
US6533768B1 (en) 2000-04-14 2003-03-18 The Regents Of The University Of California Device for glaucoma treatment and methods thereof
US20020143284A1 (en) 2001-04-03 2002-10-03 Hosheng Tu Drug-releasing trabecular implant for glaucoma treatment
US20050049578A1 (en) 2000-04-14 2005-03-03 Hosheng Tu Implantable ocular pump to reduce intraocular pressure
US20040111050A1 (en) 2000-04-14 2004-06-10 Gregory Smedley Implantable ocular pump to reduce intraocular pressure
US20030060752A1 (en) 2000-04-14 2003-03-27 Olav Bergheim Glaucoma device and methods thereof
US6638239B1 (en) 2000-04-14 2003-10-28 Glaukos Corporation Apparatus and method for treating glaucoma
US7708711B2 (en) 2000-04-14 2010-05-04 Glaukos Corporation Ocular implant with therapeutic agents and methods thereof
US7867186B2 (en) 2002-04-08 2011-01-11 Glaukos Corporation Devices and methods for treatment of ocular disorders
US20050277864A1 (en) 2000-04-14 2005-12-15 David Haffner Injectable gel implant for glaucoma treatment
GB0010871D0 (en) 2000-05-06 2000-06-28 Duckworth & Kent Ltd Opthalmic injector
ATE464031T1 (en) 2000-05-08 2010-04-15 Optima Ltd I NON-PENETRATING FILTRATION SURGERY
US9603741B2 (en) 2000-05-19 2017-03-28 Michael S. Berlin Delivery system and method of use for the eye
US8679089B2 (en) 2001-05-21 2014-03-25 Michael S. Berlin Glaucoma surgery methods and systems
DE60131273T2 (en) 2000-05-19 2008-08-28 Michael S. Beverly Hills Berlin LASER APPLICATION SYSTEM AND METHOD FOR EYE-USE
US6561974B1 (en) 2000-05-31 2003-05-13 Grieshaber & Co. Ag Schaffhausen Device for use in a surgical procedure on an eye of a living being, and method of retracting the iris
WO2001097727A1 (en) 2000-06-19 2001-12-27 Glaukos Corporation Stented trabecular shunt and methods thereof
US6582453B1 (en) 2000-07-14 2003-06-24 Opus Medical, Inc. Method and apparatus for attaching connective tissues to bone using a suture anchoring device
US6629992B2 (en) 2000-08-04 2003-10-07 Advanced Cardiovascular Systems, Inc. Sheath for self-expanding stent
US6699211B2 (en) 2000-08-22 2004-03-02 James A. Savage Method and apparatus for treatment of glaucoma
FR2813521B1 (en) 2000-09-01 2003-06-13 Ioltechnologie Production GLAUCOME DRAIN
US6428501B1 (en) 2000-09-19 2002-08-06 K2 Limited Partnership U/A/D Surgical instrument sleeve
US6730056B1 (en) 2000-09-21 2004-05-04 Motorola, Inc. Eye implant for treating glaucoma and method for manufacturing same
US6962573B1 (en) 2000-10-18 2005-11-08 Wilcox Michael J C-shaped cross section tubular ophthalmic implant for reduction of intraocular pressure in glaucomatous eyes and method of use
US6428566B1 (en) 2000-10-31 2002-08-06 Advanced Cardiovascular Systems, Inc. Flexible hoop and link sheath for a stent delivery system
WO2002036052A1 (en) 2000-11-01 2002-05-10 Glaukos Corporation Glaucoma treatment device
DE10062478A1 (en) 2000-12-14 2002-07-04 Glautec Ag Glaucoma treatment device
US6544208B2 (en) 2000-12-29 2003-04-08 C. Ross Ethier Implantable shunt device
US6595945B2 (en) 2001-01-09 2003-07-22 J. David Brown Glaucoma treatment device and method
US6881198B2 (en) 2001-01-09 2005-04-19 J. David Brown Glaucoma treatment device and method
CN1486158A (en) 2001-01-17 2004-03-31 人类光学股份公司 Implant for determining intra-ocular pressure
WO2002056805A2 (en) 2001-01-18 2002-07-25 The Regents Of The University Of California Minimally invasive glaucoma surgical instrument and method
US6827738B2 (en) 2001-01-30 2004-12-07 Timothy R. Willis Refractive intraocular implant lens and method
CA2439114C (en) 2001-02-23 2009-10-27 Ras Holding Corp System for making incisions for scleral eye implants
JP4121372B2 (en) 2001-02-27 2008-07-23 千寿製薬株式会社 Biodegradable polymer-type drug release system
EP1367968A4 (en) 2001-03-16 2006-12-13 Glaukos Corp Applicator and methods for placing a trabecular shunt for glaucoma treatment
US6585753B2 (en) 2001-03-28 2003-07-01 Scimed Life Systems, Inc. Expandable coil stent
US7488303B1 (en) 2002-09-21 2009-02-10 Glaukos Corporation Ocular implant with anchor and multiple openings
US6666841B2 (en) 2001-05-02 2003-12-23 Glaukos Corporation Bifurcatable trabecular shunt for glaucoma treatment
US7431710B2 (en) 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
EP1977724A1 (en) 2001-04-07 2008-10-08 Glaukos Corporation System for treating ocular disorders
US6981958B1 (en) 2001-05-02 2006-01-03 Glaukos Corporation Implant with pressure sensor for glaucoma treatment
DE10118933A1 (en) 2001-04-18 2002-11-14 Glautec Ag Glaucoma treatment device
AT409586B (en) 2001-04-26 2002-09-25 Clemens Dr Vass Implant draining aqueous humor from anterior chamber of eye into Schlemm's channel, includes fixation plate for stabilization on sclera
AU2002347269A1 (en) 2001-05-01 2003-01-02 Glaukos Corporation Glaucoma device and methods thereof
US7678065B2 (en) 2001-05-02 2010-03-16 Glaukos Corporation Implant with intraocular pressure sensor for glaucoma treatment
US7094225B2 (en) 2001-05-03 2006-08-22 Glaukos Corporation Medical device and methods of use of glaucoma treatment
US6533769B2 (en) 2001-05-03 2003-03-18 Holmen Joergen Method for use in cataract surgery
US8267995B2 (en) 2001-08-03 2012-09-18 David Castillejos Method and intra sclera implant for treatment of glaucoma and presbyopia
RU2197206C1 (en) 2001-08-15 2003-01-27 Свадовский Александр Игоревич Method for treating the cases of glaucoma
CN1592640A (en) 2001-08-16 2005-03-09 Gmp视觉方案公司 Shunt device and method for treating glaucoma
US7331984B2 (en) 2001-08-28 2008-02-19 Glaukos Corporation Glaucoma stent for treating glaucoma and methods of use
IN2014DN10834A (en) 2001-09-17 2015-09-04 Psivida Inc
US6767346B2 (en) 2001-09-20 2004-07-27 Endocare, Inc. Cryosurgical probe with bellows shaft
US7879046B2 (en) * 2001-10-01 2011-02-01 Depuy Mitek, Inc. Suturing apparatus and method
US6554843B1 (en) 2001-10-15 2003-04-29 Universal Optical Co., Ltd. Cataract instrument
US20030097151A1 (en) 2001-10-25 2003-05-22 Smedley Gregory T. Apparatus and mitochondrial treatment for glaucoma
US7163543B2 (en) 2001-11-08 2007-01-16 Glaukos Corporation Combined treatment for cataract and glaucoma treatment
US20030093084A1 (en) 2001-11-13 2003-05-15 Optonol Ltd. Delivery devices for flow regulating implants
JP4427327B2 (en) 2001-11-15 2010-03-03 イオプティマ リミテッド Non-perforated leaky surgery
US6802829B2 (en) 2001-11-16 2004-10-12 Infinite Vision, Llc Spray device
US8491549B2 (en) 2001-11-21 2013-07-23 Iscience Interventional Corporation Ophthalmic microsurgical system
CA2467993C (en) 2001-11-22 2011-01-11 Eduard Anton Haefliger Device and method for the performance of ophthalmological operations
US20030105456A1 (en) 2001-12-04 2003-06-05 J.T. Lin Apparatus and methods for prevention of age-related macular degeneration and other eye diseases
US6893413B2 (en) 2002-01-07 2005-05-17 Eric C. Martin Two-piece stent combination for percutaneous arterialization of the coronary sinus and retrograde perfusion of the myocardium
US6966888B2 (en) 2002-01-13 2005-11-22 Eagle Vision, Inc. Sinus valved glaucoma shunt
US20030153863A1 (en) 2002-02-13 2003-08-14 Patel Anilbhai S. Implant system for glaucoma surgery
WO2003073968A2 (en) 2002-02-28 2003-09-12 Gmp Vision Solutions, Inc. Device and method for monitoring aqueous flow within the eye
US7186232B1 (en) 2002-03-07 2007-03-06 Glaukoa Corporation Fluid infusion methods for glaucoma treatment
US20060200113A1 (en) 2002-03-07 2006-09-07 David Haffner Liquid jet for glaucoma treatment
US7951155B2 (en) 2002-03-15 2011-05-31 Glaukos Corporation Combined treatment for cataract and glaucoma treatment
US20030229303A1 (en) 2002-03-22 2003-12-11 Haffner David S. Expandable glaucoma implant and methods of use
US6902577B2 (en) 2002-03-29 2005-06-07 Isaac Lipshitz Intraocular lens implant with mirror
US20040147870A1 (en) 2002-04-08 2004-07-29 Burns Thomas W. Glaucoma treatment kit
US20030195438A1 (en) 2002-04-12 2003-10-16 Petillo Phillip J. Method and apparatus to treat glaucoma
US20040024345A1 (en) 2002-04-19 2004-02-05 Morteza Gharib Glaucoma implant with valveless flow bias
US7041114B2 (en) 2002-05-01 2006-05-09 D.O.T. Dan Ophthalmic Technologies Ltd. Surgical tool and method for extracting tissue from wall of an organ
WO2003099103A2 (en) 2002-05-20 2003-12-04 Refocus Group, Inc. System and method for determining a position for a scleral pocket for a scleral prosthesis
CA2487733C (en) 2002-05-29 2011-07-05 University Of Saskatchewan Technologies Inc. A shunt and method treatment of glaucoma
ES2279156T3 (en) * 2002-06-11 2007-08-16 Tyco Healthcare Group Lp MALE TIGHTS FOR HERNIAS.
US20040243227A1 (en) 2002-06-13 2004-12-02 Guided Delivery Systems, Inc. Delivery devices and methods for heart valve repair
US20030236483A1 (en) 2002-06-25 2003-12-25 Ren David H Dual drainage ocular shunt for glaucoma
US20070219632A1 (en) 2002-08-02 2007-09-20 David Castillejos Method and intra-sclera implant for treatment of glaucoma and presbyopia
US7192412B1 (en) 2002-09-14 2007-03-20 Glaukos Corporation Targeted stent placement and multi-stent therapy
US7699882B2 (en) 2002-09-17 2010-04-20 Iscience Interventional Corporation Apparatus and method for surgical bypass of aqueous humor
US7468065B2 (en) 2002-09-18 2008-12-23 Allergan, Inc. Apparatus for delivery of ocular implants
EP1539065B1 (en) 2002-09-18 2012-12-12 Allergan, Inc. Apparatus for delivery of ocular implants
USRE40722E1 (en) 2002-09-27 2009-06-09 Surmodics, Inc. Method and apparatus for coating of substrates
US7192484B2 (en) 2002-09-27 2007-03-20 Surmodics, Inc. Advanced coating apparatus and method
AU2003291377A1 (en) 2002-11-06 2004-06-03 Gmp Vision Solutions, Inc. Storage apparatus for surgical implant device
US7001426B2 (en) 2002-11-18 2006-02-21 The Institute For Eye Research One-piece minicapsulorhexis valve
US20040102832A1 (en) 2002-11-21 2004-05-27 Doty David R. Stent delivery and retention apparatus
US7160264B2 (en) 2002-12-19 2007-01-09 Medtronic-Xomed, Inc. Article and method for ocular aqueous drainage
US7544368B2 (en) 2002-12-20 2009-06-09 Life Spring Biotech Co., Ltd. Structure for modulating intraocular pressure
JP2004208898A (en) 2002-12-27 2004-07-29 Japan Science & Technology Agency Hydatoid discharging implant for glaucoma treatment
US20040216749A1 (en) 2003-01-23 2004-11-04 Hosheng Tu Vasomodulation during glaucoma surgery
WO2004066980A2 (en) 2003-01-24 2004-08-12 Control Delivery Systems, Inc. Sustained release device and method for ocular delivery of carbonic anhydrase inhibitors
US20040162545A1 (en) 2003-02-14 2004-08-19 Brown J. David Bypass for glaucoma drainage device
ES2642584T3 (en) 2003-02-18 2017-11-16 Hampar Karageozian Device to drain fluids and reduce intraocular pressure
US8012115B2 (en) 2003-02-18 2011-09-06 S.K. Pharmaceuticals, Inc. Optic nerve implants
US7297154B2 (en) 2003-02-24 2007-11-20 Maxwell Sensors Inc. Optical apparatus for detecting and treating vulnerable plaque
USD490152S1 (en) 2003-02-28 2004-05-18 Glaukos Corporation Surgical handpiece
US20050209672A1 (en) 2004-03-02 2005-09-22 Cardiomind, Inc. Sliding restraint stent delivery systems
US20040193262A1 (en) 2003-03-29 2004-09-30 Shadduck John H. Implants for treating ocular hypertension, methods of use and methods of fabrication
US20040193095A1 (en) 2003-03-29 2004-09-30 Shadduck John H. Implants for treating ocular hypertension, methods of use and methods of fabrication
WO2004093761A1 (en) 2003-04-16 2004-11-04 Iscience Surgical Corporation Opthalmic microsurgical instruments
US20050038498A1 (en) 2003-04-17 2005-02-17 Nanosys, Inc. Medical device applications of nanostructured surfaces
US7025740B2 (en) 2003-04-22 2006-04-11 Ahmed A Mateen Device for treating glaucoma & method of manufacture
US20040236343A1 (en) 2003-05-23 2004-11-25 Taylor Jon B. Insertion tool for ocular implant and method for using same
EP1631204B1 (en) 2003-06-10 2012-04-04 Neomedix Corporation Tubular cutter device
EP1633236B1 (en) 2003-06-10 2013-04-10 Neomedix Corporation Device for treatment of glaucoma and other surgical procedures and method of producing such device
EP2314241B1 (en) * 2003-06-13 2013-08-07 Covidien LP Multiple member interconnect for surgical instrument and absorbable screw fastener
AU2004247272A1 (en) 2003-06-16 2004-12-23 Solx, Inc. Shunt for the treatment of glaucoma
EP3168304A1 (en) 2003-08-27 2017-05-17 Ophthotech Corporation Combination therapy for the treatment of ocular neovascular disorders
US20050055075A1 (en) 2003-09-08 2005-03-10 Leonard Pinchuk Methods for the manufacture of porous prostheses
US7291125B2 (en) 2003-11-14 2007-11-06 Transcend Medical, Inc. Ocular pressure regulation
EP1689333B1 (en) 2003-12-05 2014-02-12 Innfocus, Inc. Improved glaucoma implant device
EP1698369B1 (en) 2003-12-15 2009-12-09 Terumo Kabushiki Kaisha Catheter assembly
WO2005069831A2 (en) 2004-01-12 2005-08-04 Iscience Surgical Corporation Injector for viscous materials
AU2005208820A1 (en) 2004-01-22 2005-08-11 Solx, Inc. Glaucoma treatment method
EP1715827B1 (en) 2004-01-23 2010-12-29 iScience Interventional Corporation Composite ophthalmic microcannula
US20050250788A1 (en) 2004-01-30 2005-11-10 Hosheng Tu Aqueous outflow enhancement with vasodilated aqueous cavity
US7544176B2 (en) 2005-06-21 2009-06-09 Becton, Dickinson And Company Glaucoma implant having MEMS flow module with flexing diaphragm for pressure regulation
US7384550B2 (en) 2004-02-24 2008-06-10 Becton, Dickinson And Company Glaucoma implant having MEMS filter module
US20060036207A1 (en) 2004-02-24 2006-02-16 Koonmen James P System and method for treating glaucoma
US7364564B2 (en) 2004-03-02 2008-04-29 Becton, Dickinson And Company Implant having MEMS flow module with movable, flow-controlling baffle
US7803150B2 (en) 2004-04-21 2010-09-28 Acclarent, Inc. Devices, systems and methods useable for treating sinusitis
US7156821B2 (en) 2004-04-23 2007-01-02 Massachusetts Eye & Ear Infirmary Shunt with enclosed pressure-relief valve
US7758612B2 (en) * 2004-04-27 2010-07-20 Tyco Healthcare Group Lp Surgery delivery device and mesh anchor
US8114099B2 (en) 2004-04-27 2012-02-14 Tyco Healthcare Group Lp Absorbable anchor for hernia mesh fixation
KR20070036044A (en) 2004-04-29 2007-04-02 아이싸이언스 인터벤셔날 코포레이션 Apparatus and method for ocular treatment
US20100173866A1 (en) 2004-04-29 2010-07-08 Iscience Interventional Corporation Apparatus and method for ocular treatment
US20080058704A1 (en) 2004-04-29 2008-03-06 Michael Hee Apparatus and Method for Ocular Treatment
MXPA06012460A (en) 2004-04-29 2007-07-13 Iscience Surgical Corp Apparatus and method for surgical enhancement of aqueous humor drainage.
US8673341B2 (en) 2004-04-30 2014-03-18 Allergan, Inc. Intraocular pressure reduction with intracameral bimatoprost implants
WO2005122953A2 (en) 2004-05-11 2005-12-29 Oregon Health And Science University Interfacial stent and method of maintaining patency of surgical fenestrations
US7357778B2 (en) 2004-05-20 2008-04-15 Ajay Bhalla Aqueous drainage and flow regulating implant
AU2005249966A1 (en) 2004-05-27 2005-12-15 Clarity Corporation Glaucoma shunt
US20060293612A1 (en) * 2004-06-24 2006-12-28 Boston Scientific Scimed, Inc. Apparatus and method for treating occluded vasculature
US7862531B2 (en) 2004-06-25 2011-01-04 Optonol Ltd. Flow regulating implants
US20060032507A1 (en) 2004-08-11 2006-02-16 Hosheng Tu Contrast-enhanced ocular imaging
US8246569B1 (en) 2004-08-17 2012-08-21 California Institute Of Technology Implantable intraocular pressure drain
US20060067978A1 (en) 2004-09-29 2006-03-30 Bausch & Lomb Incorporated Process for preparing poly(vinyl alcohol) drug delivery devices
TWI369970B (en) 2004-10-20 2012-08-11 Beaver Visitec Int Us Inc Surgical knife safety handle having user operable lock
US7905904B2 (en) * 2006-02-03 2011-03-15 Biomet Sports Medicine, Llc Soft tissue repair device and associated methods
US20060173397A1 (en) 2004-11-23 2006-08-03 Hosheng Tu Ophthalmology implants and methods of manufacture
US7594899B2 (en) 2004-12-03 2009-09-29 Innfocus, Llc Glaucoma implant device
US20070118065A1 (en) 2004-12-03 2007-05-24 Leonard Pinchuk Glaucoma Implant Device
US7837644B2 (en) 2004-12-03 2010-11-23 Innfocus, Llc Glaucoma implant device
US20060129129A1 (en) 2004-12-10 2006-06-15 Cloud Farm Associates, L.P. Eye implant devices and method and device for implanting such devices for treatment of glaucoma
US20120010702A1 (en) 2004-12-16 2012-01-12 Iscience Interventional Corporation Ophthalmic implant for treatment of glaucoma
EP1833440B1 (en) 2004-12-16 2012-08-22 Iscience Interventional Corporation Ophthalmic implant for treatment of glaucoma
US7713228B2 (en) 2005-01-28 2010-05-11 Alcon, Inc. Surgical method
AR054647A1 (en) 2005-02-21 2007-07-11 Maldonado Bas Arturo DEVICE FOR WATER HUMOR DRAINAGE IN GLAUCOMA CASES
US9186274B2 (en) 2005-02-23 2015-11-17 Camras Vision Inc. Method and apparatus for reducing intraocular pressure
CN101160144A (en) 2005-02-23 2008-04-09 苏尔莫迪克斯公司 Implantable medical articles having laminin coatings and methods of use
US7641627B2 (en) 2005-02-23 2010-01-05 Camras Carl B Method and apparatus for reducing intraocular pressure
US20060217741A1 (en) 2005-03-28 2006-09-28 Ghannoum Ziad R Irrigation tip
US20130079759A1 (en) 2005-04-14 2013-03-28 Robert S. Dotson Ophthalmic Phototherapy Device and Associated Treatment Method
US20080269730A1 (en) 2005-04-14 2008-10-30 Dotson Robert S Ophthalmic Phototherapy Device and Associated Treatment Method
WO2006121066A1 (en) 2005-05-10 2006-11-16 Takuya Kataoka Ophthalmologic laser treatment instrument
CA2608150A1 (en) 2005-05-10 2006-11-16 The Regents Of The University Of California Self-clearing catheter for clinical implantation
US20070021653A1 (en) 2005-06-27 2007-01-25 Lars-Olof Hattenbach Device for the injection of drugs into microvessels
US20090043365A1 (en) 2005-07-18 2009-02-12 Kolis Scientific, Inc. Methods, apparatuses, and systems for reducing intraocular pressure as a means of preventing or treating open-angle glaucoma
US20080108932A1 (en) 2005-08-24 2008-05-08 Rodgers M Steven MEMS filter module with multi-level filter traps
US20070156079A1 (en) 2005-09-16 2007-07-05 Bg Implant, Inc. Glaucoma Treatment Devices and Methods
US20070073390A1 (en) 2005-09-23 2007-03-29 Medlogics Device Corporation Methods and devices for enhanced adhesion between metallic substrates and bioactive material-containing coatings
JP2009509650A (en) 2005-09-26 2009-03-12 アテヌークス・テクノロジーズ・インコーポレーテッド Pressure damping device
US7717872B2 (en) 2005-09-28 2010-05-18 Rajesh Kumar Shetty Fluid shunting apparatus and methods
US7771388B2 (en) 2005-10-12 2010-08-10 Daniel Olsen Steerable catheter system
US7655831B2 (en) 2005-10-19 2010-02-02 Prywes Arnold S Method for fluid control in medical applications
US7959632B2 (en) 2005-10-20 2011-06-14 Fugo Richard J Plasma incising device including disposable incising tips for performing surgical procedures
TW200733993A (en) 2005-11-03 2007-09-16 Reseal Internat Ltd Partnership Continuously sealing one way valve assembly and fluid delivery system and formulations for use therein
US20070106200A1 (en) 2005-11-08 2007-05-10 Brian Levy Intraocular shunt device and method
EP1960013B1 (en) 2005-11-18 2016-12-21 The Board of Regents of The University of Texas System Methods for coating surfaces with antimicrobial agents
US20070161981A1 (en) 2006-01-06 2007-07-12 Arthrocare Corporation Electrosurgical method and systems for treating glaucoma
EP3632385A1 (en) 2006-01-17 2020-04-08 Novartis AG Glaucoma treatment device
US8585753B2 (en) 2006-03-04 2013-11-19 John James Scanlon Fibrillated biodegradable prosthesis
EP1832289A3 (en) 2006-03-08 2007-12-12 Sahajanand Medical Technologies PVT. ltd Compositions and coatings for implantable medical devices
JP2009534129A (en) 2006-04-18 2009-09-24 カスケード オフタルミクス Intraocular pressure attenuator
US7520876B2 (en) 2006-04-21 2009-04-21 Entellus Medical, Inc. Device and method for treatment of sinusitis
US20080039931A1 (en) 2006-04-25 2008-02-14 Surmodics, Inc. Hydrophilic shape memory insertable medical articles
ES2396088T3 (en) 2006-04-26 2013-02-19 Eastern Virginia Medical School Systems to monitor and control the internal pressure of an eye or a body part
US20070293807A1 (en) 2006-05-01 2007-12-20 Lynch Mary G Dual drainage pathway shunt device and method for treating glaucoma
WO2007131050A2 (en) 2006-05-02 2007-11-15 Georgia Tech Research Corporation Method for drug delivery to ocular tissue using microneedle
US20070292470A1 (en) 2006-06-15 2007-12-20 Medtronic Vascular, Inc. Implantable Medical Devices and Methods for Making the Same
US8668676B2 (en) 2006-06-19 2014-03-11 Allergan, Inc. Apparatus and methods for implanting particulate ocular implants
US20070293873A1 (en) 2006-06-19 2007-12-20 Allergan, Inc. Apparatus and methods for implanting particulate ocular implants
US7458953B2 (en) 2006-06-20 2008-12-02 Gholam A. Peyman Ocular drainage device
US7909789B2 (en) 2006-06-26 2011-03-22 Sight Sciences, Inc. Intraocular implants and methods and kits therefor
US8663303B2 (en) 2010-11-15 2014-03-04 Aquesys, Inc. Methods for deploying an intraocular shunt from a deployment device and into an eye
US8721702B2 (en) 2010-11-15 2014-05-13 Aquesys, Inc. Intraocular shunt deployment devices
US8852137B2 (en) 2010-11-15 2014-10-07 Aquesys, Inc. Methods for implanting a soft gel shunt in the suprachoroidal space
US20120197175A1 (en) 2006-06-30 2012-08-02 Aquesys, Inc. Methods, systems and apparatus for relieving pressure in an organ
EP2043572B1 (en) 2006-06-30 2014-12-31 Aquesys Inc. Apparatus for relieving pressure in an organ
US8758290B2 (en) 2010-11-15 2014-06-24 Aquesys, Inc. Devices and methods for implanting a shunt in the suprachoroidal space
US20080243243A1 (en) 2006-07-07 2008-10-02 Williams Stuart K Implantable medical articles having pro-healing coatings
ES2418842T3 (en) 2006-07-11 2013-08-16 Refocus Group, Inc. Scleral prosthesis to treat presbyopia and other ocular disorders and related insertion devices
US9039761B2 (en) 2006-08-04 2015-05-26 Allergan, Inc. Ocular implant delivery assemblies with distal caps
ES2533901T3 (en) 2006-08-10 2015-04-15 California Institute Of Technology Microfluidic valves with floating element and manufacturing procedure
WO2008022093A2 (en) 2006-08-11 2008-02-21 Mynosys Cellular Devices, Inc. Microsurgery for treatment of glaucoma
US8043235B2 (en) 2006-08-22 2011-10-25 Schwartz Donald N Ultrasonic treatment of glaucoma
MX2009001920A (en) 2006-08-22 2009-04-14 Donald N Schwartz Ultrasonic treatment of glucoma.
US20080097214A1 (en) 2006-09-05 2008-04-24 Capistrano Labs, Inc. Ophthalmic ultrasound probe assembly
US20100241046A1 (en) 2006-09-06 2010-09-23 Innfocus, Llc Apparatus, methods and devices for treatment of ocular disorders
US20080109037A1 (en) * 2006-11-03 2008-05-08 Musculoskeletal Transplant Foundation Press fit suture anchor and inserter assembly
US20080147083A1 (en) 2006-11-09 2008-06-19 Vold Steven D Method and device for fixation of ophthalmic tissue
US20080114440A1 (en) 2006-11-13 2008-05-15 Sage Medical Technologies, Inc Methods and devices for deploying an implant in curved anatomy
FR2909883B1 (en) 2006-12-18 2012-11-30 Commissariat Energie Atomique MULTI-ARM SENSOR AND SYSTEM FOR DEEP ELECTRICAL NEUROSTIMULATION COMPRISING SUCH A PROBE
US20100114309A1 (en) 2006-12-26 2010-05-06 De Juan Jr Eugene Drug delivery implants for inhibition of optical defects
AR058947A1 (en) 2007-01-08 2008-03-05 Consejo Nac Invest Cient Tec IMPLANTABLE MICROAPARATE IN THE EYE TO RELIEF GLAUCOMA OR CAUSING DISEASE OF EYE OVERPRESSION
US20080200923A1 (en) 2007-01-09 2008-08-21 Richard Beckman Insertion tool for ocular implant and method for using same
JP5201743B2 (en) 2007-01-09 2013-06-05 フォヴェア ファルマシューティカル Intraocular injection device
DE102007004906A1 (en) 2007-01-25 2008-07-31 Universität Rostock eye implant
US8066768B2 (en) 2007-01-29 2011-11-29 Werblin Research & Development Corp. Intraocular lens system
US20080188860A1 (en) 2007-02-07 2008-08-07 Vold Steven D Ophthalmic surgical apparatus
USD606190S1 (en) 2007-02-08 2009-12-15 Aderans Research Institute, Inc. Device for delivering cellular material and physiologic fluids to a subject
WO2008096821A1 (en) 2007-02-08 2008-08-14 Kaneka Corporation Injector for eye
WO2008106421A2 (en) 2007-02-27 2008-09-04 Ast Products, Inc. Instrument for injecting an ophthalmic device into an eye
US8366653B2 (en) 2007-03-13 2013-02-05 University Of Rochester Intraocular pressure regulating device
US20080243247A1 (en) 2007-03-26 2008-10-02 Poley Brooks J Method and apparatus for prevention and treatment of adult glaucoma
US20080243156A1 (en) 2007-03-30 2008-10-02 Thomas John Ophthalmic surgical instrument & surgical methods
US20080255545A1 (en) 2007-04-10 2008-10-16 Mansfield John M Apparatus and method for treating the inside of an eye
US7931660B2 (en) 2007-05-10 2011-04-26 Tyco Healthcare Group Lp Powered tacker instrument
US20080306429A1 (en) 2007-06-07 2008-12-11 Shields Milton B Uveoscleral drainage device
US8197418B2 (en) 2007-06-08 2012-06-12 Cornell University Microprobes
EP2173289A4 (en) 2007-07-17 2010-11-24 Transcend Medical Inc Ocular implant with hydrogel expansion capabilities
US20090043242A1 (en) 2007-08-07 2009-02-12 Becton, Dickinson And Company Instruments and methods for implanting corneal implant via extra-and intra-cameral routes
US8734377B2 (en) 2007-09-24 2014-05-27 Ivantis, Inc. Ocular implants with asymmetric flexibility
US20090082862A1 (en) 2007-09-24 2009-03-26 Schieber Andrew T Ocular Implant Architectures
US8425449B2 (en) 2009-07-09 2013-04-23 Ivantis, Inc. Ocular implants and methods for delivering ocular implants into the eye
US7740604B2 (en) 2007-09-24 2010-06-22 Ivantis, Inc. Ocular implants for placement in schlemm's canal
US8945103B2 (en) 2007-10-30 2015-02-03 Iridex Corporation Contact probe for the delivery of laser energy
US8083759B2 (en) 2007-11-02 2011-12-27 Refocus Ocular, Inc. Apparatuses and methods for forming incisions in ocular tissue
US20090177138A1 (en) 2007-11-07 2009-07-09 Brown Reay H Shunt Device for Glaucoma Treatment
USD592746S1 (en) 2007-11-08 2009-05-19 Alimera Sciences Ocular implantation device
EP2214608B1 (en) 2007-11-08 2015-03-04 Alimera Sciences, Inc. Ocular implantation device
US20090124973A1 (en) 2007-11-09 2009-05-14 D Agostino Eduardo Insertion mechanism for use with a syringe
US8512404B2 (en) 2007-11-20 2013-08-20 Ivantis, Inc. Ocular implant delivery system and method
EP2417946A1 (en) 2007-11-23 2012-02-15 Ecole Polytechnique Fédérale de Lausanne (EPFL) Non-invasively adjustable drainage device
US20090137992A1 (en) 2007-11-27 2009-05-28 Ravi Nallakrishnan Apparatus and Method for Treating Glaucoma
KR101725117B1 (en) 2008-01-07 2017-04-10 살루타리스 메디컬 디바이스즈, 인코퍼레이티드 Devices for minimally-invasive extraocular delivery of radiation to the posterior portion of the eye
JP2011510750A (en) 2008-01-29 2011-04-07 クライマン、ギルバート・エイチ Drug delivery device, kit and methods thereof
US9539138B2 (en) 2008-01-30 2017-01-10 Takaya TANAKA Method of ophthalmic surgery and kit therefor
US8109896B2 (en) 2008-02-11 2012-02-07 Optonol Ltd. Devices and methods for opening fluid passageways
CA2717441A1 (en) 2008-03-05 2009-09-11 Ivantis, Inc. Methods and apparatus for treating glaucoma
US20110082385A1 (en) 2008-04-17 2011-04-07 Yale University Method for implanting intraocular pressure sensor
TWI542338B (en) 2008-05-07 2016-07-21 壯生和壯生視覺關懷公司 Ophthalmic devices for the controlled release of active agents
CN102123713A (en) 2008-05-09 2011-07-13 Qlt栓塞输送公司 Sustained release delivery of active agents to treat glaucoma and ocular hypertension
ES2542302T3 (en) 2008-05-15 2015-08-04 Mynosys Cellular Devices, Inc. Ophthalmic surgical device for capsulotomy
US20090287233A1 (en) 2008-05-15 2009-11-19 Huculak John C Small Gauge Mechanical Tissue Cutter/Aspirator Probe For Glaucoma Surgery
US8157759B2 (en) 2008-05-16 2012-04-17 Ocumatrix, Inc. Method and apparatus for fluid drainage of the eye
US8702995B2 (en) 2008-05-27 2014-04-22 Dober Chemical Corp. Controlled release of microbiocides
US8894602B2 (en) 2010-09-17 2014-11-25 Johnson & Johnson Vision Care, Inc. Punctal plugs with directional release
ES2640867T3 (en) 2008-06-25 2017-11-07 Novartis Ag Eye implant with ability to change shape
US8628492B2 (en) 2008-07-01 2014-01-14 California Institute Of Technology Implantable glaucoma drainage device
EP2328527A1 (en) 2008-07-08 2011-06-08 QLT Plug Delivery, Inc. Lacrimal implant body including comforting agent
US20100056977A1 (en) 2008-08-26 2010-03-04 Thaddeus Wandel Trans-corneal shunt and method
US8353856B2 (en) 2008-11-05 2013-01-15 Abbott Medical Optics Inc. Glaucoma drainage shunts and methods of use
US7695135B1 (en) 2008-11-11 2010-04-13 Boston Foundation For Sight Scleral lens with scalloped channels or circumferential fenestrated channels
US8079972B2 (en) 2008-11-20 2011-12-20 Schocket Stanley S Implant for use in surgery for glaucoma and a method
CA2745884C (en) 2008-12-05 2017-08-01 Ivantis, Inc. Cannula for ocular implant delivery system
US20120257167A1 (en) 2008-12-17 2012-10-11 Glaukos Corporation Gonioscope for improved viewing
WO2010077987A1 (en) 2008-12-17 2010-07-08 Glaukos Corporation Gonioscope for improved viewing
US20100158980A1 (en) 2008-12-18 2010-06-24 Casey Kopczynski Drug delivery devices for delivery of therapeutic agents
CH700161A2 (en) 2008-12-22 2010-06-30 Grieshaber Ophthalmic Res Foun IMPLANT FOR INTRODUCING into Schlemm's canal AN EYE.
TW201026300A (en) 2009-01-02 2010-07-16 Alcon Res Ltd In-situ refillable ophthalmic implant
US8545554B2 (en) 2009-01-16 2013-10-01 Allergan, Inc. Intraocular injector
JP5524983B2 (en) 2009-01-28 2014-06-18 トランセンド・メディカル・インコーポレイテッド Implant system
CA2757037C (en) 2009-01-29 2019-08-06 Forsight Vision4, Inc. Posterior segment drug delivery
US20100225061A1 (en) 2009-03-09 2010-09-09 Bath David L System and method for gaming with an engagable projectile
AU2010229789B2 (en) 2009-03-26 2014-11-13 Johnson & Johnson Surgical Vision, Inc. Glaucoma shunts with flow management and improved surgical performance
US8337393B2 (en) 2009-04-03 2012-12-25 Transcend Medical, Inc. Ocular implant delivery systems and methods
WO2015073571A1 (en) 2013-11-15 2015-05-21 Dose Medical Corporation Ocular implants configured to store and release stable drug formulations
US20230053931A1 (en) 2009-05-18 2023-02-23 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
WO2010135369A1 (en) 2009-05-18 2010-11-25 Dose Medical Corporation Drug eluting ocular implant
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
US8764696B2 (en) 2009-06-16 2014-07-01 Mobius Therapeutics, Inc. Medical drainage devices with carbon-based structures for inhibiting growth of fibroblasts
AU2010271274B2 (en) 2009-07-09 2015-05-21 Alcon Inc. Single operator device for delivering an ocular implant
CA2768842A1 (en) 2009-07-24 2011-01-27 Oregon Health And Science University Interfacial stent and method of maintaining patency of surgical fenestrations
US20110118835A1 (en) 2009-08-13 2011-05-19 Matthew Silvestrini Branched ocular implant
US8951221B2 (en) 2009-08-20 2015-02-10 Grieshaber Ophthalmic Research Foundation Method and device for the treatment of glaucoma
US8307701B2 (en) * 2009-08-20 2012-11-13 Lawrence Andrew Laricchiuta Engine pulley testing device
US8545431B2 (en) 2009-09-21 2013-10-01 Alcon Research, Ltd. Lumen clearing valve for glaucoma drainage device
US8257295B2 (en) 2009-09-21 2012-09-04 Alcon Research, Ltd. Intraocular pressure sensor with external pressure compensation
US8419673B2 (en) 2009-09-21 2013-04-16 Alcon Research, Ltd. Glaucoma drainage device with pump
US8721580B2 (en) 2009-09-21 2014-05-13 Alcon Research, Ltd. Power saving glaucoma drainage device
US20110071454A1 (en) 2009-09-21 2011-03-24 Alcon Research, Ltd. Power Generator For Glaucoma Drainage Device
US9119951B2 (en) 2009-10-12 2015-09-01 Kona Medical, Inc. Energetic modulation of nerves
WO2011046949A2 (en) 2009-10-12 2011-04-21 The Regents Of The University Of Colorado, A Body Corporate Implants for reducing intraocular pressure
CA2778452A1 (en) 2009-10-23 2011-04-28 Ivantis, Inc. Ocular implant system and method
US8771216B2 (en) 2009-11-06 2014-07-08 University Hospitals Of Cleveland Fluid communication device and method of use thereof
US8845572B2 (en) 2009-11-13 2014-09-30 Grieshaber Ophthalmic Research Foundation Method and device for the treatment of glaucoma
WO2011081897A1 (en) 2009-12-15 2011-07-07 Alcon Research, Ltd. High-intensity pulsed electric field vitrectomy apparatus
WO2011084550A2 (en) 2009-12-16 2011-07-14 Eyevation, Llc Delivery and extraction devices
USD645489S1 (en) 2009-12-16 2011-09-20 Glaukos Corporation Gonioscopic system including an optical element attachment
USD645490S1 (en) 2009-12-16 2011-09-20 Glaukos Corporation Gonioscopic system including an optical element attachment
WO2011097408A1 (en) 2010-02-05 2011-08-11 Sight Sciences, Inc Intraocular implants and related kits and methods
US20110202049A1 (en) 2010-02-18 2011-08-18 Alcon Research, Ltd. Small Gauge Ablation Probe For Glaucoma Surgery
US20110230877A1 (en) 2010-03-16 2011-09-22 Alcon Research, Ltd. Pulsed Electric Field Probe for Glaucoma Surgery
US9320647B2 (en) 2010-03-31 2016-04-26 Ocuject, Llc Device and method for intraocular drug delivery
US20110245753A1 (en) 2010-04-05 2011-10-06 Sunalp Murad A Apparatus and method for lowering intraocular pressure in an eye
CN103037911B (en) 2010-04-08 2015-07-15 矽瑞奥科技公司 Implantable medical devices having microporous surface layers and method for reducing foreign body response to the same
US20110248671A1 (en) 2010-04-08 2011-10-13 Alcon Research, Ltd. Power System Implantable in Eye
US8308799B2 (en) 2010-04-20 2012-11-13 Alcon Research, Ltd. Modular intraocular lens injector device
CN103002842A (en) 2010-05-27 2013-03-27 I科学干预公司 Device for placing circumferential implant in schlemm's canal
US8444589B2 (en) 2010-06-09 2013-05-21 Transcend Medical, Inc. Ocular implant with fluid outflow pathways having microporous membranes
US8545430B2 (en) 2010-06-09 2013-10-01 Transcend Medical, Inc. Expandable ocular devices
WO2011163505A1 (en) 2010-06-23 2011-12-29 Ivantis, Inc. Ocular implants deployed in schlemm's canal of the eye
US10576304B2 (en) 2010-06-29 2020-03-03 Sunnybrook Research Institute Thermal therapy apparatus and method using focused ultrasonic sound fields
US8449490B2 (en) 2010-09-11 2013-05-28 Aleeva Medical Inc. Disc shunt delivery with stepped needle
US8915877B2 (en) 2010-10-12 2014-12-23 Emmett T. Cunningham, JR. Glaucoma drainage device and uses thereof
US9370444B2 (en) 2010-10-12 2016-06-21 Emmett T. Cunningham, JR. Subconjunctival conformer device and uses thereof
US20120271272A1 (en) 2010-10-15 2012-10-25 Iscience Interventional Corporation Device for ocular access
US8585629B2 (en) 2010-11-15 2013-11-19 Aquesys, Inc. Systems for deploying intraocular shunts
US9668915B2 (en) 2010-11-24 2017-06-06 Dose Medical Corporation Drug eluting ocular implant
US20120238994A1 (en) 2010-12-22 2012-09-20 Martin Nazzaro Two-piece injectable drug delivery device with heat-cured seal
EP2663271B1 (en) 2011-01-14 2014-12-03 Ecole Polytechnique Federale de Lausanne (EPFL) Apparatus and methods for treating excess intraocular fluid
WO2012099873A1 (en) 2011-01-18 2012-07-26 Minipums, Llc Surgical implantation instrument
EP2517619B1 (en) 2011-04-27 2013-05-22 Istar Medical Improvements in or relating to glaucoma management and treatment
US20120283557A1 (en) 2011-05-05 2012-11-08 Berlin Michael S Methods and Apparatuses for the Treatment of Glaucoma using visible and infrared ultrashort laser pulses
US8747299B2 (en) 2011-06-02 2014-06-10 Grieshaber Ophtalmic Research Foundation Method and device for the pathology analysis of the Schlemm's canal
US20120310137A1 (en) 2011-06-02 2012-12-06 Silvestrini Thomas A Eye shunt with porous structure
US10245178B1 (en) 2011-06-07 2019-04-02 Glaukos Corporation Anterior chamber drug-eluting ocular implant
US8657776B2 (en) 2011-06-14 2014-02-25 Ivantis, Inc. Ocular implants for delivery into the eye
US10285855B2 (en) 2011-08-05 2019-05-14 Mynosys Cellular Devices, Inc. Capsulotomy device with suction cup compression chamber
EP3659495B1 (en) 2011-09-13 2022-12-14 Dose Medical Corporation Intraocular physiological sensor
JP6015226B2 (en) 2011-09-30 2016-10-26 株式会社ニデック Intraocular lens insertion device
US9072588B2 (en) 2011-10-03 2015-07-07 Alcon Research, Ltd. Selectable varied control valve systems for IOP control systems
US8585631B2 (en) 2011-10-18 2013-11-19 Alcon Research, Ltd. Active bimodal valve system for real-time IOP control
US8753305B2 (en) 2011-12-06 2014-06-17 Alcon Research, Ltd. Bubble-driven IOP control system
US8771220B2 (en) 2011-12-07 2014-07-08 Alcon Research, Ltd. Glaucoma active pressure regulation shunt
US10080682B2 (en) 2011-12-08 2018-09-25 Aquesys, Inc. Intrascleral shunt placement
US8852136B2 (en) 2011-12-08 2014-10-07 Aquesys, Inc. Methods for placing a shunt into the intra-scleral space
US8840578B2 (en) 2011-12-09 2014-09-23 Alcon Research, Ltd. Multilayer membrane actuators
US8579848B2 (en) 2011-12-09 2013-11-12 Alcon Research, Ltd. Active drainage systems with pressure-driven valves and electronically-driven pump
US8585664B2 (en) 2011-12-12 2013-11-19 Alcon Research, Ltd System and method for powering ocular implants
US20130150777A1 (en) 2011-12-12 2013-06-13 Sebastian Böhm Glaucoma Drainage Devices Including Vario-Stable Valves and Associated Systems and Methods
US8603024B2 (en) 2011-12-12 2013-12-10 Alcon Research, Ltd. Glaucoma drainage devices including vario-stable valves and associated systems and methods
WO2013090231A1 (en) 2011-12-13 2013-06-20 Alcon Research, Ltd. Active drainage systems with dual-input pressure-driven valves
US9339187B2 (en) 2011-12-15 2016-05-17 Alcon Research, Ltd. External pressure measurement system and method for an intraocular implant
US8663150B2 (en) 2011-12-19 2014-03-04 Ivantis, Inc. Delivering ocular implants into the eye
US8945214B2 (en) * 2011-12-19 2015-02-03 Allergan, Inc. Intravitreal applicator
US9101444B2 (en) 2012-01-12 2015-08-11 Innfocus, Inc. Method, surgical kit and device for treating glaucoma
US9241831B2 (en) 2012-02-13 2016-01-26 Iridex Corporation Reduction of intraocular pressure in the eye using a tubular clip
US8986240B2 (en) 2012-02-14 2015-03-24 Alcon Research, Ltd. Corrugated membrane actuators
US9155653B2 (en) 2012-02-14 2015-10-13 Alcon Research, Ltd. Pressure-driven membrane valve for pressure control system
WO2013148275A2 (en) 2012-03-26 2013-10-03 Glaukos Corporation System and method for delivering multiple ocular implants
US8998838B2 (en) 2012-03-29 2015-04-07 Alcon Research, Ltd. Adjustable valve for IOP control with reed valve
US9241832B2 (en) 2012-04-24 2016-01-26 Transcend Medical, Inc. Delivery system for ocular implant
RU2649460C2 (en) 2012-06-04 2018-04-03 Алькон Фармасьютикалз, Лтд. Intraocular lens insertion device
US9308082B2 (en) 2012-08-07 2016-04-12 RegenEye, L.L.C. Ocular collar stent for treating narrowing of the irideocorneal angle
US8864701B2 (en) 2012-08-13 2014-10-21 Alcon Research, Ltd. Implantable MEMS device and method
US8956320B2 (en) 2012-08-28 2015-02-17 Alcon Research, Ltd. Capillary valve
US9132034B2 (en) 2012-10-01 2015-09-15 Alcon Research, Ltd. Valve position sensor
US9763829B2 (en) 2012-11-14 2017-09-19 Novartis Ag Flow promoting ocular implant
US9730638B2 (en) 2013-03-13 2017-08-15 Glaukos Corporation Intraocular physiological sensor
WO2014145021A1 (en) 2013-03-15 2014-09-18 Orange County Glaucoma, Pc Enhancement of aqueous flow
US10517759B2 (en) 2013-03-15 2019-12-31 Glaukos Corporation Glaucoma stent and methods thereof for glaucoma treatment
US9592151B2 (en) 2013-03-15 2017-03-14 Glaukos Corporation Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye
US9226851B2 (en) 2013-08-24 2016-01-05 Novartis Ag MEMS check valve chip and methods
US9289324B2 (en) 2013-08-26 2016-03-22 Novartis Ag Externally adjustable passive drainage device
US9283115B2 (en) 2013-08-26 2016-03-15 Novartis Ag Passive to active staged drainage device
RU2728195C2 (en) 2014-02-26 2020-07-28 Аллерган, Инк. Device for delivery of intraocular implant and methods of its use
WO2015154049A1 (en) 2014-04-04 2015-10-08 Altaviz, Llc Intraocular lens inserter
WO2015184173A1 (en) 2014-05-29 2015-12-03 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
US10391206B2 (en) 2014-07-30 2019-08-27 University Of Kansas Cannula for external drainage of subretinal fluid
US20170252209A1 (en) 2014-08-12 2017-09-07 Patrick GOOI Device, Delivery System, And Method For Ocular Therapy
US10588780B2 (en) 2015-03-04 2020-03-17 Alcon Inc. Intraocular lens injector
AU2016235432B2 (en) 2015-03-20 2020-02-27 Glaukos Corporation Gonioscopic devices
CN107530190B (en) 2015-03-31 2021-03-02 美国商业眼科医疗器械公司 Ophthalmic delivery systems and methods
US10299958B2 (en) 2015-03-31 2019-05-28 Sight Sciences, Inc. Ocular delivery systems and methods
WO2016187355A1 (en) 2015-05-20 2016-11-24 Glaukos Corporation Therapeutic drug compositions and implants for delivery of same
WO2017015633A1 (en) 2015-07-22 2017-01-26 Glaukos Corporation Ocular implants for reduction of intraocular pressure
CN108135470B (en) 2015-08-14 2021-03-09 伊万提斯公司 Ocular implant with pressure sensor and delivery system
WO2017040853A1 (en) 2015-09-02 2017-03-09 Glaukos Corporation Drug delivery implants with bi-directional delivery capacity
WO2017040855A1 (en) 2015-09-02 2017-03-09 Dose Medical Corporation Drug delivery implants as intraocular drug depots and methods of using same
WO2017046358A1 (en) 2015-09-17 2017-03-23 Medterials, Inc. Ophthalmic injection device
US11564833B2 (en) 2015-09-25 2023-01-31 Glaukos Corporation Punctal implants with controlled drug delivery features and methods of using same
JP6647022B2 (en) * 2015-11-27 2020-02-14 株式会社三共 Gaming machine
JP6969876B2 (en) 2016-02-29 2021-11-24 メディセル・アーゲー Transmission mechanism, especially injectors with gear trains
WO2017184881A1 (en) 2016-04-20 2017-10-26 Harold Alexander Heitzmann Bioresorbable ocular drug delivery device
JP6764259B2 (en) 2016-05-31 2020-09-30 川崎重工業株式会社 Electronic component insertion device
EP3506863A4 (en) 2016-09-02 2020-04-29 Envisia Therapeutics Inc. Implant applicators
US10674906B2 (en) 2017-02-24 2020-06-09 Glaukos Corporation Gonioscopes
USD833008S1 (en) 2017-02-27 2018-11-06 Glaukos Corporation Gonioscope
US10835419B2 (en) 2017-08-17 2020-11-17 Aspip Inc. Method, device and system for treatment of elevated intraocular pressure
CN107498340A (en) 2017-09-26 2017-12-22 上海航天精密机械研究所 Resetting workpiece free form holding meanss and method
US11116625B2 (en) 2017-09-28 2021-09-14 Glaukos Corporation Apparatus and method for controlling placement of intraocular implants
JP7457648B2 (en) 2017-09-29 2024-03-28 グローコス コーポレーション Intraocular physiological sensors
US11376040B2 (en) 2017-10-06 2022-07-05 Glaukos Corporation Systems and methods for delivering multiple ocular implants
USD846738S1 (en) 2017-10-27 2019-04-23 Glaukos Corporation Implant delivery apparatus
WO2019200336A1 (en) 2018-04-12 2019-10-17 New World Medical, Inc. Device and method for intraocular fluid injection
US20220119350A1 (en) 2019-02-22 2022-04-21 Glaukos Corporation Compounds for the treatment of ocular disease

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050271704A1 (en) * 2002-04-08 2005-12-08 Hosheng Tu Injectable glaucoma implants with multiple openings
WO2008061043A2 (en) * 2006-11-10 2008-05-22 Glaukos Corporation Uveoscleral shunt and methods for implanting same
WO2010093945A2 (en) * 2009-02-13 2010-08-19 Glaukos Corporation Uveoscleral drug delivery implant and methods for implanting the same
US20110112546A1 (en) * 2009-07-29 2011-05-12 Juan Jr Eugene De Ocular implant applier and methods of use

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