WO2007091991A3 - Simultaneous beam-focus and coherence-gate tracking for real-time optical coherence tomography - Google Patents

Simultaneous beam-focus and coherence-gate tracking for real-time optical coherence tomography Download PDF

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Publication number
WO2007091991A3
WO2007091991A3 PCT/US2006/001097 US2006001097W WO2007091991A3 WO 2007091991 A3 WO2007091991 A3 WO 2007091991A3 US 2006001097 W US2006001097 W US 2006001097W WO 2007091991 A3 WO2007091991 A3 WO 2007091991A3
Authority
WO
WIPO (PCT)
Prior art keywords
sample
tracking
gft
path length
optical path
Prior art date
Application number
PCT/US2006/001097
Other languages
French (fr)
Other versions
WO2007091991A2 (en
Inventor
Xingde Li
Original Assignee
Univ Washington
Xingde Li
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington, Xingde Li filed Critical Univ Washington
Publication of WO2007091991A2 publication Critical patent/WO2007091991A2/en
Publication of WO2007091991A3 publication Critical patent/WO2007091991A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/02055—Reduction or prevention of errors; Testing; Calibration
    • G01B9/02062—Active error reduction, i.e. varying with time
    • G01B9/02063—Active error reduction, i.e. varying with time by particular alignment of focus position, e.g. dynamic focussing in optical coherence tomography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0066—Optical coherence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6852—Catheters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/02001—Interferometers characterised by controlling or generating intrinsic radiation properties
    • G01B9/02002—Interferometers characterised by controlling or generating intrinsic radiation properties using two or more frequencies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/02049—Interferometers characterised by particular mechanical design details
    • G01B9/0205—Interferometers characterised by particular mechanical design details of probe head
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/0209—Low-coherence interferometers
    • G01B9/02091—Tomographic interferometers, e.g. based on optical coherence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4795—Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0068—Confocal scanning
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B2290/00—Aspects of interferometers not specifically covered by any group under G01B9/02
    • G01B2290/65—Spatial scanning object beam

Abstract

Method and apparatus for achieving dynamic focus tracking during real-time optical coherence tomography (OCT) by simultaneously implementing geometric focus tracking (GFT) and coherence gate tracking (CGT). GFT tracking involves changing a position of the focal point of the OCT probe (114) in the sample (124) during scanning. Preferably, the focal point is moved relative to the sample without disrupting the Gaussian beam profile of the scanner. CGT involves determining a change in the optical path length of the sample arm due to the GFT, and calculating the change in the optical path length in the reference arm (111) required to maintain an equivalent optical path length in both the sample arm and the reference arm. The reference arm is then translated by the required amount, to maximize the OCT signal. A lateral priority scanning technique is employed, and this technique can be implemented using a single optical fiber suitable for endoscopic use.
PCT/US2006/001097 2005-01-14 2006-01-13 Simultaneous beam-focus and coherence-gate tracking for real-time optical coherence tomography WO2007091991A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64433505P 2005-01-14 2005-01-14
US60/644,335 2005-01-14

Publications (2)

Publication Number Publication Date
WO2007091991A2 WO2007091991A2 (en) 2007-08-16
WO2007091991A3 true WO2007091991A3 (en) 2007-11-01

Family

ID=38345575

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/001097 WO2007091991A2 (en) 2005-01-14 2006-01-13 Simultaneous beam-focus and coherence-gate tracking for real-time optical coherence tomography

Country Status (1)

Country Link
WO (1) WO2007091991A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8218927B2 (en) 2010-04-19 2012-07-10 National Research Council Of Canada Optical catheter with rotary optical cap
DE102011016852A1 (en) * 2011-04-06 2012-10-11 Laser- Und Medizin-Technologie Gmbh, Berlin Device for detecting light in cavities or lumens in medical catheters, has light waves leading fiber whose end portion is formed as concave mirror at predetermined angle with respect to longitudinal axis
WO2014085911A1 (en) 2012-12-05 2014-06-12 Tornado Medical Systems, Inc. System and method for wide field oct imaging
CN103799975B (en) * 2014-02-26 2015-11-18 中国科学院光电技术研究所 Adopt the adaptive optics OCT retinal imager of relevant door Wavefront sensor
US9192295B1 (en) 2014-06-11 2015-11-24 L&R Medical Inc. Focusing algorithm in OCT-only systems
EP3021071B1 (en) 2014-11-12 2020-09-23 Haag-Streit Ag Surveying method for the ophthalmology
EP3655748B1 (en) 2017-07-18 2023-08-09 Perimeter Medical Imaging, Inc. Sample container for stabilizing and aligning excised biological tissue samples for ex vivo analysis

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459570A (en) * 1991-04-29 1995-10-17 Massachusetts Institute Of Technology Method and apparatus for performing optical measurements
US20040181148A1 (en) * 2001-10-31 2004-09-16 Olympus Corporation Optical scanning observation apparatus
US20050105096A1 (en) * 2001-02-17 2005-05-19 Fee Michale S. Acousto-optic monitoring and imaging in a depth sensitive manner

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459570A (en) * 1991-04-29 1995-10-17 Massachusetts Institute Of Technology Method and apparatus for performing optical measurements
US20050105096A1 (en) * 2001-02-17 2005-05-19 Fee Michale S. Acousto-optic monitoring and imaging in a depth sensitive manner
US20040181148A1 (en) * 2001-10-31 2004-09-16 Olympus Corporation Optical scanning observation apparatus

Also Published As

Publication number Publication date
WO2007091991A2 (en) 2007-08-16

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