WO1999066871A1 - Intraocular pressure regulating valve - Google Patents

Intraocular pressure regulating valve Download PDF

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Publication number
WO1999066871A1
WO1999066871A1 PCT/MX1999/000018 MX9900018W WO9966871A1 WO 1999066871 A1 WO1999066871 A1 WO 1999066871A1 MX 9900018 W MX9900018 W MX 9900018W WO 9966871 A1 WO9966871 A1 WO 9966871A1
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WO
WIPO (PCT)
Prior art keywords
valve
intraocular pressure
eye
retainer
patient
Prior art date
Application number
PCT/MX1999/000018
Other languages
Spanish (es)
French (fr)
Inventor
Ricardo Cruz Perez
Francisco Carmona Dominguez
Original Assignee
Ricardo Cruz Perez
Francisco Carmona Dominguez
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from MXPA/A/1998/005876A external-priority patent/MXPA98005876A/en
Application filed by Ricardo Cruz Perez, Francisco Carmona Dominguez filed Critical Ricardo Cruz Perez
Priority to AU43990/99A priority Critical patent/AU4399099A/en
Publication of WO1999066871A1 publication Critical patent/WO1999066871A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment

Definitions

  • FIG 1 represents a conventional perspective of the eyeball, where the implanted valve (A) is shown in a position that does not interfere with the extraocular muscles (B) or with the optic nerve (C).
  • the Feeding Tube inserted into the anterior chamber of the eye (D) can be seen, which was done through a puncture performed under a cut or flap of the sclera (E), which has subsequently been sutured to protect the site from the insertion
  • the valve is attached to the sclera by other sutures (F).
  • the whole set is installed under the conjunctival membrane and covered by it, which shows the previous cut for implantation, closed at the end by very fine sutures (G).
  • said conjunctival membrane has been considered transparent, being that in reality it is translucent.
  • FIG. 1 is an assembly drawing with three views, showing the different parts that make up the valve, which are:
  • FIG. 3 presents a comparative table with the general dimensions of other implants on the market, in order to appreciate the difference in size against the valve of our invention. It is clear that implants commercially known as Ahmed, Baerveldt, Krupin and Molteno are of the type of aqueous uptake in a reservoir that distributes it for absorption in the surrounding tissues, forming and depending on a blister that restricts its excessive outflow.
  • the Optimed implant which is the only one of smaller dimensions than the valve of our invention, can be discarded since it is only a replacement or filter of a porous material placed in the tube outlet, without any control
  • Figure 4 is the four-view drawing of the "C" Body of the Valve. See that, the lower face which, when mounted, will be in contact with the sclera, follows a curvature that coincides with that of the eyeball, in its scleral part.
  • ears From its outer edge are born two extensions or "ears” (1) perforated that will serve to hold it, by means of sutures to the eyeball in its scleral part
  • the front part (2) it has a tubular inlet extension to couple the Feeder Tube "D", in which its inner diameter must be slightly smaller than the outside of the tube, so that it is held under pressure
  • the stop for insertion (3) is given by a change in diameters that, forming a conicity, must be greater than the size of the Feeder Tube, to prevent any solid detritus that has managed to travel here to create a blockage of the flow at this point
  • This "C" Body component must be manufactured by injection thermoplastic molding, followed by detailed checks that cover the correct filling of the mold, the dimensional accuracy and the proper rebabeo
  • the perforations for sutures in the "ears" can be drilled in the already injected part.
  • the input gauge can only appear indicated in the molding, to be drilled like a post-machined machining
  • the material to be used must be rigid, non-stick inert, non-hygroscopic and long-term aging These characteristics are met by Polypropylene, Polycarbonate, Polymethylmethacrylate (PMMA), and some other alternatives
  • Figure 5 corresponds to Retainer "B", which is the element that provides the action of allowing the flow of the liquid that exceeds the pressure anticipated in the anterior chamber of the eye, or of preventing such flow when the eye is restored. Its outer profile must conform to the dimensions of the housing cavity in the Body "C"
  • This piece must be less than the depth of the housing cavity so that, the clearance of those heights, causes the tongue not to drag on the bottom of the cavity or on the lid impeding its free movement. This time, this clearance will allow the passage of the expelled liquid into the veins of the drain.
  • the pressure required to overcome the tongue is determined by its own wall thickness and the hardness (Shore A) of the elastomer used for its molding. In this way it can be manufactured in vain graduations, the most common being to relieve pressure that exceeds 14 mm Hg
  • the material for its manufacture must be flexible, inert, non-stick, non-hygroscopic and long-term aging, characteristics that meet the VITON and some other most recent development engineering elastomers
  • Figure 6 depicts the "A" closure cap that serves to keep the assembly assembled and to separate Retainer "B” from surrounding tissues.
  • FIG. 7 shows the Feeder Tube “D”, consisting of a flexible tube that fits with the entrance in the body "C"
  • One of its ends (1) must be cut at 45 ° with respect to the axis, to facilitate its insertion into the anterior chamber of the eye which will be done through a puncture with a puncture element calibrated to the size of the tube, during the operation implant surgery
  • two slots or windows (2) must be machined (preferably with laser) facing each other, as shown in the drawing, not exceeding 1 mm in length, since the tube will be inserted into its distal portion 2 to 3 mm These will function as a filter (pichancha) by multiplying the passage area and allowing the flow even if some solid detritus of the aqueous humor blocks the front entrance (3)
  • this feeder tube must be delivered or supplied to exceed the requirement of greater length that is present in the implant surgeries, so that the Wrong, after estimating the correct dimension for its case, cuts it by the opposite end ( 4) to the insertion tip before installing
  • the material for its manufacture must be semi-flexible, inert, non-stick and long-term aging, characteristics that extruded Silicon meets, which has already been demonstrated in practice, with other implant models, be adequate.

Abstract

The invention relates to a valve (A) intended to be used in the medical field, in ophtalmological surgery; when implanted in a patient's eye suffering from excessive intraocular pressure (glaucoma), the valve will drain the aqueous humour from the anterior chamber of the eye until the desired pressure is obtained and will then stop the flow. The object of the invention is to provide an implant which is totally different from those which exist in the market owing to its small size which will reduce the discomfort for the patient and interferences with the extraocular muscles (B) and with the optical nerve (C). The internal construction of the valve is characterized essentially by a retainer element (4) with flexible tongue with maintains constantly and with accuracy the optimal intraocular pressure, thereby preventing hypotony and its serious medical consequences. Other designed details provide for a better operation of the valve in the long term, free of jamming which would make the system useless.

Description

"VÁLVULA REGULADORA DE LA PRESIÓN INTRAOCULAR" "INTRAOCULAR PRESSURE REGULATING VALVE"
PARA EL CAMPO MEDICO, ESPECIALMENTE EN CIRUGÍA OFTALMOLÓGICA, DIRIGIDA AL TRATAMIENTO DE LA PRESIÓN INTRAOCULAR ELEVADA, QUE PRODUCE LA ENFERMEDAD CONOCIDA COMO GLAUCOMA.FOR THE MEDICAL FIELD, ESPECIALLY IN OPHTHALMOLOGICAL SURGERY, DIRECTED TO THE TREATMENT OF HIGH INTRAOCULAR PRESSURE, WHICH CAUSES THE DISEASE KNOWN AS GLAUCOMA.
ANTECEDENTES DE LA INVENCIÓNBACKGROUND OF THE INVENTION
En la actualidad hay implantes específicos para aliviar una presión intraocular elevada (glaucoma). Tales implantes, a través de un tubo insertado a la cámara anterior del ojo, drenan el humor acuoso hacia receptáculos de almacenamiento y absorción en los tejidos extraoculares, formando y dependiendo de una ampolla de tejido circundante que es lo que "restringe" la salida del acuoso. Este sistema está expuesto a muchas variables orgánicas y por lo mismo es impreciso, pues no tiene ningún recurso para regular efectivamente el flujo, por lo que se presta a hipotonía postoperatoria, con sus implicaciones médicamente conocidas en el ojo implantado.There are currently specific implants to relieve high intraocular pressure (glaucoma). Such implants, through a tube inserted into the anterior chamber of the eye, drain the aqueous humor into storage and absorption receptacles in the extraocular tissues, forming and depending on a blister of surrounding tissue that is what "restricts" the exit of the aqueous. This system is exposed to many organic variables and therefore is inaccurate, since it has no recourse to effectively regulate the flow, so it lends itself to postoperative hypotonia, with its medically known implications in the implanted eye.
En otros casos se pretende regular el flujo mediante suturas que opriman al tubo de drenaje, pero su funcionamiento también es evidentemente impreciso e incontrolable.In other cases it is intended to regulate the flow by means of sutures that oppress the drain tube, but its operation is also obviously imprecise and uncontrollable.
A fin de aliviar de una manera eficaz la presión intraocular que provoca glaucoma, sin que se corra el riesgo de hipotonía, se ha desarrollado una válvula de regulación exacta que recibiendo el humor acuoso a través del mismo sistema insertado (aunque con alguna mejora), libere con precisión únicamente el exceso de líquido necesario para restablecer la presión intraocular deseada, cerrando el paso al haberse restablecido ésta. In order to effectively relieve the intraocular pressure that causes glaucoma, without the risk of hypotonia, an exact regulation valve has been developed that receives aqueous humor through the same inserted system (although with some improvement), accurately release only the excess fluid necessary to restore the desired intraocular pressure, closing the passage after it has been restored.
DESCRIPCIÓN DE LA INVENCIÓNDESCRIPTION OF THE INVENTION
Los detalles característicos de ésta novedosa válvula de regulación exacta para mantener una presión intraocular óptima en ojos afectados por glaucoma, se muestran y describen claramente en la siguiente descripción y en los cinco dibujos que la acompañan.The characteristic details of this novel valve of exact regulation to maintain an optimal intraocular pressure in eyes affected by glaucoma, are clearly shown and described in the following description and in the five accompanying drawings.
La Figura 1 representa una perspectiva convencional del globo ocular, donde se muestra la válvula implantada (A) en posición tal que no interfiere con los músculos extraoculares (B) ni con el nervio óptico (C). Se aprecia el Tubo Alimentador insertado al interior de la cámara anterior del ojo (D), lo que se efectuó a través de una punción practicada bajo un corte o colgajo de la esclera (E), que posteriormente se ha suturado para proteger el sitio de la inserción. La válvula se encuentra sujeta a la esclera mediante otras suturas (F). Todo el conjunto se instala bajo la membrana conjuntival y cubierto por ella, de la que se muestra el corte previo para su implantación, cerrado al finalizar mediante suturas muy finas (G). A fin de que la válvula pueda verse en el dibujo, dicha membrana conjuntival se ha considerado transparente, siendo que en la realidad es translúcida.Figure 1 represents a conventional perspective of the eyeball, where the implanted valve (A) is shown in a position that does not interfere with the extraocular muscles (B) or with the optic nerve (C). The Feeding Tube inserted into the anterior chamber of the eye (D) can be seen, which was done through a puncture performed under a cut or flap of the sclera (E), which has subsequently been sutured to protect the site from the insertion The valve is attached to the sclera by other sutures (F). The whole set is installed under the conjunctival membrane and covered by it, which shows the previous cut for implantation, closed at the end by very fine sutures (G). In order that the valve can be seen in the drawing, said conjunctival membrane has been considered transparent, being that in reality it is translucent.
La Figura 2 es un dibujo de conjunto a tres vistas, donde se muestran las diferentes partes que integran la válvula, que son:Figure 2 is an assembly drawing with three views, showing the different parts that make up the valve, which are:
A.- TapaA.- Cover
B.- ReténB.- Catch
C- CuerpoC- Body
D - Tubo AlimentadorD - Feeder Tube
En la vista de planta del dibujo, se muestra sin la tapa para ver el interior del conjunto. Considerando que se presenta en una escala aproximada de 10:1 , puede tenerse una idea de su tamaño real, que es mucho menor que cualquiera de los implantes de almacenamiento que existen en el mercado, lo cual presentara mayor comodidad al paciente y reducirá el riesgo de interferencia con los músculos extraoculares y el nervio óptico.In the plan view of the drawing, it is shown without the cover to see the inside of the set. Considering that it is presented on an approximate scale of 10: 1, you can get an idea of its actual size, which is much smaller than any of the storage implants that exist in the market, which will present greater comfort to the patient and reduce the risk of interference with extraocular muscles and optic nerve.
La Figura 3 presenta una tabla comparativa con las dimensiones generales de otros implantes que hay en el mercado, para poder apreciar la diferencia de tamaño contra la válvula de nuestra invención. Cabe aclarar que los implantes comercialmente conocidos como Ahmed, Baerveldt, Krupin y Molteno son del tipo de captación del acuoso en un depósito que lo distribuye para su absorción en los tejidos circundantes, formando y dependiendo de una ampolla que restrinja su salida excesiva.Figure 3 presents a comparative table with the general dimensions of other implants on the market, in order to appreciate the difference in size against the valve of our invention. It is clear that implants commercially known as Ahmed, Baerveldt, Krupin and Molteno are of the type of aqueous uptake in a reservoir that distributes it for absorption in the surrounding tissues, forming and depending on a blister that restricts its excessive outflow.
El implante Optimed, que es el único de menores dimensiones que la válvula de nuestra invención, puede descartarse ya que solamente se trata de una restπcción o filtro de un material poroso colocado en la salida del tubo, sin ningún controlThe Optimed implant, which is the only one of smaller dimensions than the valve of our invention, can be discarded since it is only a replacement or filter of a porous material placed in the tube outlet, without any control
De esta manera se hace notar que, en nuestra invención, gracias a las características del diseño en la forma del cuerpo y de su retén, se logra obtener una acción valvular y una funcionalidad superior, con un tamaño muy pequeño el menor entre los implantes que se ofrecen en el mercado lo que beneficia al paciente por las razones ya expuestas en la descπpción de la Figura 2In this way it is noted that, in our invention, thanks to the characteristics of the design in the shape of the body and its retainer, it is possible to obtain a valvular action and superior functionality, with a smaller size the smaller among the implants that what benefits the patient is offered in the market for the reasons already stated in the description of Figure 2
La Figura 4 es el dibujo a cuatro vistas del Cuerpo "C" de ia Válvula Véase que, la cara inferior que al montarse quedará en contacto con ia esclerótica, sigue una curvatura que coincide con la del globo ocular, en su parte escleral.Figure 4 is the four-view drawing of the "C" Body of the Valve. See that, the lower face which, when mounted, will be in contact with the sclera, follows a curvature that coincides with that of the eyeball, in its scleral part.
De su borde exterior nacen dos extensiones u "orejas' (1) perforadas que servirán para sujetarlo, mediante suturas al globo ocular en su parte escleralFrom its outer edge are born two extensions or "ears " (1) perforated that will serve to hold it, by means of sutures to the eyeball in its scleral part
En la parte frontal (2) presenta una extensión tubular de entrada para acoplar el Tubo Alimentador "D", en la que su diámetro interior debe ser ligeramente menor que el exterior del tubo, para que éste se sujete a presión El tope para la inserción (3) lo da un cambio de diámetros que, formando una conicidad, deben ser mayores que el calibre del Tubo Alimentador, para prevenir que algún detritus sólido que haya logrado viajar hasta aquí cree un bloqueo del flujo en este puntoIn the front part (2) it has a tubular inlet extension to couple the Feeder Tube "D", in which its inner diameter must be slightly smaller than the outside of the tube, so that it is held under pressure The stop for insertion (3) is given by a change in diameters that, forming a conicity, must be greater than the size of the Feeder Tube, to prevent any solid detritus that has managed to travel here to create a blockage of the flow at this point
En la parte central (4) se tiene una cavidad para alojar al Retén "B" la cual, para asegurar su correcto posicionamiento, es de forma oblonga. Sobre el borde de la cavidad se tiene una superficie escalonada (5) para montar la Tapa "A". En la parte posterior (6) esta provisto de unas ranuras interconectadas por un canal para drenaje del liquido que será absorbido por los tejidos circundantes Estas ranuras protegen los pasajes de salida para que no se vean invadidos por crecimiento tisular Tengase en cuenta que el volumen del liquido a drenar es muy pequeñoIn the central part (4) there is a cavity to accommodate Retainer "B" which, to ensure its correct positioning, is oblong. On the edge of the cavity there is a stepped surface (5) to mount the Cover "A". In the rear part (6) it is provided with interconnected grooves by a channel for draining the liquid that will be absorbed by the surrounding tissues. These grooves protect the exit passages so that they are not invaded by tissue growth Note that the volume of the liquid to drain is very small
Este componente Cuerpo "C", debe fabricarse por moldeo de termoplastico por inyección, seguido por detalladas comprobaciones que abarquen el correcto llenado del molde, la exactitud dimensional y el rebabeo adecuado Por facilidad para la construcción del molde, de especialmente reducidas dimensiones, y para su manejo y uso, las perforaciones para sutura en las "orejas" pueden barrenarse en la pieza ya inyectada Asi mismo, el calibre de entrada puede aparecer solamente señalado en el moldeo, para barrenarse como un maquinado postenor a esteThis "C" Body component must be manufactured by injection thermoplastic molding, followed by detailed checks that cover the correct filling of the mold, the dimensional accuracy and the proper rebabeo For ease of mold construction, especially small dimensions, and for its handling and use, the perforations for sutures in the "ears" can be drilled in the already injected part. Also, the input gauge can only appear indicated in the molding, to be drilled like a post-machined machining
El material a utilizar debe ser rígido, inerte antiadheπble, no higroscópico y de largo plazo de envejecimiento Estas características las cumplen el Polipropileno, el Policarbonato, el Polimetilmetacπlato (PMMA), y algunas otras alternativasThe material to be used must be rigid, non-stick inert, non-hygroscopic and long-term aging These characteristics are met by Polypropylene, Polycarbonate, Polymethylmethacrylate (PMMA), and some other alternatives
La Figura 5 corresponde al Reten "B", que es el elemento que provee la acción de permitir el flujo del liquido que exceda la presión prevista en la cámara anterior del ojo, o de impedir tal flujo al restablecerse ésta Su perfil exterior debe ajustarse a las dimensiones de la cavidad de alojamiento en el Cuerpo "C"Figure 5 corresponds to Retainer "B", which is the element that provides the action of allowing the flow of the liquid that exceeds the pressure anticipated in the anterior chamber of the eye, or of preventing such flow when the eye is restored. Its outer profile must conform to the dimensions of the housing cavity in the Body "C"
En ia parte que se monta hacia la perforación de entrada, tiene una "lengüeta" (1) que, para abnr o cerrar, por su propia flexibilidad hará esta acción Estando el conjunto en condición libre, esto es sin instalar, esta lengüeta por su dimensionamiento debe oprimir la perforación de entrada, manteniéndola sellada, sera una presión excesiva de alimentación la que, venciendo su resorteo, permita el paso del liquidoIn the part that is mounted towards the entrance perforation, it has a "tongue" (1) that, to open or close, by its own flexibility will do this action. The assembly being in free condition, that is without installing, this tongue by its sizing must press the inlet perforation, keeping it sealed, it will be an excessive feeding pressure which, overcoming its spring, allows the passage of liquid
La altura o grosor de esta pieza debe ser menor que la profundidad de la cavidad de alojamiento de manera que, la holgura de esas alturas, haga que la lengüeta no arrastre sobre el fondo de la cavidad o sobre la tapa obstaculizando su libre movimiento A la vez, esta holgura permitirá el paso del líquido expulsado hacia las venas del drenaje La presión requerida para vencer la lengüeta la determinan su propio grueso de pared y la dureza (Shore A) del elastómero utilizado para su moldeo De esta manera se puede fabncar en vanas graduaciones, siendo la mas común aliviar la presión que exceda de 14 mm HgThe height or thickness of this piece must be less than the depth of the housing cavity so that, the clearance of those heights, causes the tongue not to drag on the bottom of the cavity or on the lid impeding its free movement. this time, this clearance will allow the passage of the expelled liquid into the veins of the drain The pressure required to overcome the tongue is determined by its own wall thickness and the hardness (Shore A) of the elastomer used for its molding. In this way it can be manufactured in vain graduations, the most common being to relieve pressure that exceeds 14 mm Hg
El material para su fabricación debe ser flexible, inerte, antiadheπble, no higroscópico y de largo plazo de envejecimiento, características que cumplen el VITON y algunos otros elastomeros de ingeniería de desarrollo mas recienteThe material for its manufacture must be flexible, inert, non-stick, non-hygroscopic and long-term aging, characteristics that meet the VITON and some other most recent development engineering elastomers
La Figura 6 representa la Tapa de cierre "A" que sirve para mantener el conjunto armado y para separar al Reten "B" de los tejidos circundantesFigure 6 depicts the "A" closure cap that serves to keep the assembly assembled and to separate Retainer "B" from surrounding tissues.
Se caracteriza por un lado plano hacia el interior y, hacia el exterior sigue la curvatura del globo ocular en su porción escleral Su perfil debe de coincidir con el del escalonamiento en el Cuerpo "C", al que se sujeta mediante ' soldadura" por puntos de calor o alta frecuenciaIt is characterized by a flat side towards the inside and, towards the outside, follows the curvature of the eyeball in its scleral portion. Its profile must coincide with that of the staggering in the Body "C", to which it is held by 'spot welding' heat or high frequency
El material para este componente y su proceso deben ser iguales que para el Cuerpo "C"The material for this component and its process must be the same as for Body "C"
En la Figura 7 se representa el Tubo Alimentador "D", consistente en un tubo flexible que embona con la entrada en el cuerpo "C"Figure 7 shows the Feeder Tube "D", consisting of a flexible tube that fits with the entrance in the body "C"
Uno de sus extremos (1) debe estar cortado a 45° respecto al eje, para facilitar su inserción a la cámara anterior del ojo lo cual se hará a través de una punción con un elemento punzante calibrado a la medida del tubo, durante la operación quirúrgica del implanteOne of its ends (1) must be cut at 45 ° with respect to the axis, to facilitate its insertion into the anterior chamber of the eye which will be done through a puncture with a puncture element calibrated to the size of the tube, during the operation implant surgery
En ese mismo extremo deben maquinarse (preferiblemente con láser) dos ranuras o ventanas (2) una frente a la otra, según se muestran en el dibujo, que no excedan de 1 mm de longitud, dado que se insertará el tubo en su porción distal de 2 a 3 mm Estas funcionarán como filtro (pichancha) multiplicando el área de paso y permitiendo el flujo aun en el caso de que algún detritus sólido del humor acuoso bloquease la entrada frontal (3)At that same end, two slots or windows (2) must be machined (preferably with laser) facing each other, as shown in the drawing, not exceeding 1 mm in length, since the tube will be inserted into its distal portion 2 to 3 mm These will function as a filter (pichancha) by multiplying the passage area and allowing the flow even if some solid detritus of the aqueous humor blocks the front entrance (3)
La longitud con que debe entregarse o surtirse este tubo alimentador debe exceder el requerimiento de mayor longitud que se presente en las cirugías de implante, de manera que el αrujano, después de estimar la dimensión correcta para su caso, lo recorte por el extremo opuesto (4) a la punta de inserción antes de instalarla El material para su fabricación debe ser semi-flexible, inerte, antiadherente y de largo plazo de envejecimiento, características que cumple el Silicon extruído, mismo que ya ha demostrado en la práctica, con otros modelos de implantes, ser el adecuado.The length with which this feeder tube must be delivered or supplied must exceed the requirement of greater length that is present in the implant surgeries, so that the Wrong, after estimating the correct dimension for its case, cuts it by the opposite end ( 4) to the insertion tip before installing The material for its manufacture must be semi-flexible, inert, non-stick and long-term aging, characteristics that extruded Silicon meets, which has already been demonstrated in practice, with other implant models, be adequate.
Por todo lo dicho anteriormente, se puede afirmar que estas características de regulación exacta del alivio y drenado de la presión excesiva del humor acuoso en la cámara anterior del globo ocular, no han sido logradas por ningún otro artefacto similar, en lo cual consiste la novedad de la invención. For all the aforementioned, it can be affirmed that these characteristics of exact regulation of the relief and drainage of excessive pressure of the aqueous humor in the anterior chamber of the eyeball, have not been achieved by any other similar device, in which the novelty consists of the invention.

Claims

REIVINDICACIONES
Habiendo descrito suficientemente nuestra invención, considero como una novedad y por lo tanto reclamo como de mi exclusiva propiedad, lo contenido en las siguientes cláusulasHaving sufficiently described our invention, I consider as a novelty and therefore claim as my exclusive property, what is contained in the following clauses
1 - Ser el único diseño de implante para aliviar la presión intraocular elevada (Glaucoma), que contiene un retén para controlar exactamente el drenado del humor acuoso en la cámara anterior del ojo. manteniendo constante la presión prevista y previniendo la hipotonía post-operatoria y sus graves consecuencias médicas, lográndose esto por la acción de resorteo de la lengüeta del retén contra la perforación de entrada del cuerpo, pudiendo así controlar la presión intraocular al nivel que se desee según la necesidad para cada caso (graduaciones) mediante la modificación del grueso de pared de dicha lengüeta y por la dureza Shore-A de su material1 - Be the only implant design to relieve elevated intraocular pressure (Glaucoma), which contains a retainer to precisely control the drainage of aqueous humor in the anterior chamber of the eye. keeping the expected pressure constant and preventing post-operative hypotonia and its serious medical consequences, this being achieved by the springing action of the tongue of the retainer against the inlet perforation of the body, thus being able to control the intraocular pressure at the level desired according to the need for each case (graduations) by modifying the wall thickness of said tongue and the Shore-A hardness of its material
2 - Mejoras en este implante consistentes en que, las características de diseño en la especial forma del cuerpo y de su reten, permiten obtener una acción valvular y un funcionamiento superior, con un tamaño muy pequeño, el menor entre los implantes que se ofrecen en el mercado, reduciendo las molestias del paciente al colocarle un dispositivo extraño en el ojo y disminuyendo notablemente el riesgo de interferencia con los músculos extraoculares que controlan el movimiento del ojo, así como con el propio nervio óptico2 - Improvements in this implant consisting in that, the design characteristics in the special shape of the body and its retainer, allow to obtain a valvular action and a superior operation, with a very small size, the smallest among the implants offered in the market, reducing the patient's discomfort by placing a strange device in the eye and significantly reducing the risk of interference with the extraocular muscles that control eye movement, as well as with the optic nerve itself
3 - Mejoras en el Tubo de Alimentación consistentes en proveerlo de ventanas en forma de ranuras que funcionen como filtro (pichancha) para multiplicar el área de acceso y prevenir que detritus sólidos presentes en el humor acuoso bloqueen su función de drenado, inutilizando todo el sistema 3 - Improvements in the Feed Tube consisting of providing windows in the form of slots that function as a filter (pichancha) to multiply the access area and prevent solid detritus present in the aqueous humor from blocking its draining function, rendering the entire system useless
PCT/MX1999/000018 1998-06-24 1999-06-22 Intraocular pressure regulating valve WO1999066871A1 (en)

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Application Number Priority Date Filing Date Title
MXPA/A/1998/005876A MXPA98005876A (en) 1998-06-24 Intraocu pressure regulator valve
MX985876 1998-06-24

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004045466A1 (en) * 2002-11-19 2004-06-03 Eagle Vision, Inc. Scleral implants for treatment of eye disorders
US8834757B2 (en) 2011-09-30 2014-09-16 Uchicago Argonne, Llc Method for making particle/polymer composites and applications

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4554918A (en) * 1982-07-28 1985-11-26 White Thomas C Ocular pressure relief device
US5041081A (en) * 1990-05-18 1991-08-20 Odrich Ronald B Ocular implant for controlling glaucoma
GB2296663A (en) * 1995-01-03 1996-07-10 Ahmed Salih Mahmud Drainage device for alleviating excess ophthalmic fluid pressure
US5626559A (en) * 1994-05-02 1997-05-06 Ramot University Authority For Applied Research And Industrial Development Ltd. Ophthalmic device for draining excess intraocular fluid

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4554918A (en) * 1982-07-28 1985-11-26 White Thomas C Ocular pressure relief device
US5041081A (en) * 1990-05-18 1991-08-20 Odrich Ronald B Ocular implant for controlling glaucoma
US5626559A (en) * 1994-05-02 1997-05-06 Ramot University Authority For Applied Research And Industrial Development Ltd. Ophthalmic device for draining excess intraocular fluid
GB2296663A (en) * 1995-01-03 1996-07-10 Ahmed Salih Mahmud Drainage device for alleviating excess ophthalmic fluid pressure

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004045466A1 (en) * 2002-11-19 2004-06-03 Eagle Vision, Inc. Scleral implants for treatment of eye disorders
US8834757B2 (en) 2011-09-30 2014-09-16 Uchicago Argonne, Llc Method for making particle/polymer composites and applications

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Publication number Publication date
AU4399099A (en) 2000-01-10

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