US8986336B2 - Apparatus and method for deployment of a bronchial obstruction device - Google Patents

Apparatus and method for deployment of a bronchial obstruction device Download PDF

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US8986336B2
US8986336B2 US13/013,070 US201113013070A US8986336B2 US 8986336 B2 US8986336 B2 US 8986336B2 US 201113013070 A US201113013070 A US 201113013070A US 8986336 B2 US8986336 B2 US 8986336B2
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capsule
housing
bronchial device
axially
bronchial
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US20110203581A1 (en
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Jenni Rimbaugh
Lauri J. DeVore
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Gyrus ACMI Inc
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Spiration Inc
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Priority to US14/665,221 priority patent/US20160015949A1/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M29/00Dilators with or without means for introducing media, e.g. remedies
    • A61M29/02Dilators made of swellable material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12104Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in an air passage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12168Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
    • A61B17/12172Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure having a pre-set deployed three-dimensional shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/24Surgical instruments, devices or methods, e.g. tourniquets for use in the oral cavity, larynx, bronchial passages or nose; Tongue scrapers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205Introduction devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/24Surgical instruments, devices or methods, e.g. tourniquets for use in the oral cavity, larynx, bronchial passages or nose; Tongue scrapers
    • A61B2017/242Surgical instruments, devices or methods, e.g. tourniquets for use in the oral cavity, larynx, bronchial passages or nose; Tongue scrapers for bronchial passages
    • A61B2019/307
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/03Automatic limiting or abutting means, e.g. for safety
    • A61B2090/037Automatic limiting or abutting means, e.g. for safety with a frangible part, e.g. by reduced diameter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2002/043Bronchi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M29/00Dilators with or without means for introducing media, e.g. remedies
    • A61M29/02Dilators made of swellable material
    • A61M2029/025Dilators made of swellable material characterised by the guiding element

Definitions

  • the present invention is generally directed to a treatment of Chronic Obstructive Pulmonary Disease (COPD).
  • COPD Chronic Obstructive Pulmonary Disease
  • the present invention is more particularly directed to an apparatus and method for deploying a bronchial device.
  • COPD Chronic Obstructive Pulmonary Disease
  • COPD chronic obstructive pulmonary disease
  • COPD chronic obstructive pulmonary disease
  • Current treatments for COPD include the prevention of further respiratory damage, pharmacotherapy, and surgery. Each is discussed below.
  • Pharmacotherapy may include bronchodilator therapy to open up the airways as much as possible or inhaled ⁇ -agonists. For those patients who respond poorly to the foregoing or who have persistent symptoms, Ipratropium bromide may be indicated. Further, courses of steroids, such as corticosteroids, may be required. Lastly, antibiotics may be required to prevent infections, and influenza and pheumococcal vaccines may be routinely administered. Unfortunately, there is no evidence that early, regular use of pharmacotherapy will alter the progression of COPD.
  • Improvements in pulmonary functions after LVRS have been attributed to at least four possible mechanisms. These include enhanced elastic recoil, correction of ventilation/perfusion mismatch, improved efficiency of respiratory musculature, and improved right ventricular filling.
  • lung transplantation is also an option.
  • COPD is the most common diagnosis for which lung transplantation is considered. Unfortunately, this consideration is given for only those with advanced COPD. Given the limited availability of donor organs, lung transplant is far from being available to all parties.
  • a lung may be collapsed by obstructing an air passageway communicating with the lung portion to be collapsed.
  • the air passageway may be obstructed by placing a bronchial obstruction device in the air passageway.
  • the bronchial obstruction device may be a plug-like device which precludes air flow in both directions or a one-way valve which permits air to be exhaled from the lung portion to be collapsed while precluding air from being inhaled into the lung portion.
  • the lung portion may be collapsed by inserting a conduit into the air passageway communicating with the lung portion to be collapsed.
  • An obstruction device such as a one-way valve is then advanced down the conduit into the air passageway.
  • the obstruction device is then deployed in the air passageway for sealing the air passageway and causing the lung portion to be collapsed.
  • a lung constriction device including a sleeve of elastic material is configured to cover at least a portion of a lung.
  • the sleeve has a pair of opened ends to permit the lung portion to be drawn into the sleeve. Once drawn therein, the lung portion is constricted by the sleeve to reduce the size of the lung portion.
  • the therapies may be combined for more effective treatment. More specifically, it has been proposed that the therapies could be administered in series, with the first mentioned therapy first applied acutely for evaluation of the effectiveness of lung size reduction in a patient and which lung portions should be reduced in size to obtain the best results.
  • the first therapy is ideal for this as it is noninvasive and could be administered in a physician's office.
  • bronchial obstruction device In order to employ the first-mentioned therapy described in U.S. Pat. No. 6,258,100, it is necessary to deploy the bronchial obstruction device within an air passageway.
  • the deployment must be reliable in that the bronchial device must be deployed in a well-controlled manner to assure placement in the proper location.
  • the bronchial device must also be deployed in a sterile manner. Patients suffering from COPD generally have compromised health. Sterile deployment may therefore prevent a catastrophic infection from occurring in those patients who are in a weakened state.
  • the present invention addresses these issues by providing bronchial obstruction device deployment systems and methods which provide more reliable device placement and sterile deployment conditions.
  • the present invention provides a device for deploying a self-expandable bronchial obstruction device in an air passageway.
  • the device includes a catheter configured to be passed down the trachea.
  • the device further includes a capsule for housing the self-expandable bronchial obstruction device in a sterile environment.
  • the capsule is further configured to be advanced down the catheter.
  • the capsule further includes a tubular extension.
  • the capsule has a breakable seam so as to release the bronchial device in the air passageway upon a proximal force being exerted upon the bronchial obstruction device.
  • the capsule may be formed of flexible material for collapsing within the catheter.
  • the invention still further provides a method of deploying a bronchial device in an air passageway.
  • the method includes guiding a conduit down a trachea into the air passageway.
  • the method further includes advancing a capsule having a bronchial device therein down an internal lumen of the conduit into the air passageway.
  • the method further includes releasing the bronchial device from the capsule.
  • the method further includes deploying the bronchial device into the air passageway.
  • the capsule may comprise a breakable seam from which the bronchial device can be released.
  • the method may further comprise pushing the bronchial device from the capsule.
  • FIG. 1 is a simplified sectional view of a thorax illustrating a healthy respiratory system
  • FIG. 2 is a sectional view similar to FIG. 1 , but illustrating a respiratory system suffering from COPD and the execution of a first step in treating the COPD condition in accordance with the present invention
  • FIG. 3 is a perspective view, illustrating a housing for the bronchial obstruction device and a conduit embodying the present invention
  • FIG. 4 is a partial cross-sectional view of the housing exiting the distal end of the conduit
  • FIG. 5 is a side view illustrating a pusher just prior to engaging the bronchial obstruction device
  • FIG. 6 is another side view illustrating the device being released from the housing by the pusher
  • FIG. 7 is another side view of the device, the housing, and the pusher immediately after the device is released from the housing;
  • FIG. 8 is a side view illustrating an intermediate step in deploying a bronchial obstruction device in accordance with an embodiment of the present invention
  • FIG. 9 is another side view illustrating a further step in the deployment of the device.
  • FIG. 10 is a side view illustrating the device after deployment.
  • FIG. 1 it is a sectional view of a healthy respiratory system.
  • the respiratory system 20 resides within the thorax 22 which occupies a space defined by the chest wall 24 and the diaphragm 26 .
  • the respiratory system 20 includes the trachea 28 , the left mainstem bronchus 30 , the right mainstem bronchus 32 , the bronchial branches 34 , 36 , 38 , 40 , and 42 and sub-branches 44 , 46 , 48 , and 50 .
  • the respiratory system 20 further includes left lung lobes 52 and 54 and right lung lobes 56 , 58 , and 60 .
  • Each bronchial branch and sub-branch communicates with a respective different portion of a lung lobe, either the entire lung lobe or a portion thereof.
  • air passageway is meant to denote either a bronchial branch or sub-branch which communicates with a corresponding individual lung lobe or lung lobe portion to provide inhaled air thereto or conduct exhaled air therefrom.
  • Characteristic of a healthy respiratory system is the arched or inwardly arcuate diaphragm 26 .
  • the diaphragm 26 straightens to increase the volume of the thorax 22 . This causes a negative pressure within the thorax. The negative pressure within the thorax in turn causes the lung lobes to fill with air.
  • the diaphragm returns to its original arched condition to decrease the volume of the thorax. The decreased volume of the thorax causes a positive pressure within the thorax which in turn causes exhalation of the lung lobes.
  • FIG. 2 illustrates a respiratory system suffering from COPD.
  • the lung lobes 52 , 54 , 56 , 58 , and 60 are enlarged and that the diaphragm 26 is not arched but substantially straight.
  • this individual is incapable of breathing normally by moving the diaphragm 28 .
  • this individual in order to create the negative pressure in the thorax 22 required for breathing, this individual must move the chest wall outwardly to increase the volume of the thorax. This results in inefficient breathing causing these individuals to breathe rapidly with shallow breaths.
  • the apex portion 62 and 66 of the upper lung lobes 52 and 56 are most affected by COPD.
  • COPD treatment or evaluation is initiated by feeding a conduit 70 down the trachea 28 , into a mainstream bronchus such as the right mainstem bronchus 32 , and into an air passageway such as the bronchial branch 42 or the bronchial sub-branch 50 .
  • the conduit 70 may be a catheter or a bronchoscope as are well-known in the art.
  • a bronchial obstruction device, contained within a housing, is then advanced down an internal lumen 71 of the conduit 70 and then released from the housing in the air passageway. Once deployed, the obstruction device precludes inhaled air from entering the lung portion to be collapsed. It is preferable that the obstruction device take the form of a one-way valve.
  • the device In addition to precluding inhaled air from entering the lung portion, the device further allows air within the lung portion to be exhaled. This results in more rapid collapse of the lung portion.
  • obstruction devices which preclude both inhaled and exhaled air flow may be deployed by the apparatus and method of the invention.
  • FIGS. 3 and 4 show a bronchial obstruction device housing 100 and a conduit 120 embodying the present invention.
  • the housing 100 forms a sealed capsule structure for housing a bronchial obstruction device 130 to be deployed within an air passageway.
  • the housing 100 has a rounded distal end 102 .
  • the rounded configuration of the distal end 102 assists in the guiding of the housing to a desired location within the air passageway.
  • the housing 100 as best seen in FIG. 4 is formed of a flexible, biocompatible material for collapsing within the internal lumen 122 of the conduit 120 as it is advanced through the conduit.
  • the housing distal end 102 further includes a score or notch 104 to enable the distal end 104 of the housing 100 to be broken-away during deployment of the device 130 without breaking the seal within the housing 100 until the time of deployment.
  • the housing still further includes a tubular extension 106 having an internal lumen 108 .
  • the lumen 108 communicates with the interior of the housing 100 during deployment of the device 130 but may be separated therefrom by a breakable wall 110 .
  • the breakable wall 110 maintains the seal of the housing while permitting a pusher to be advanced through the lumen 108 to break through the wall 110 at the time of deployment to then engage the device 130 .
  • further distal advancement of the pusher causes the device to break through the distal end 102 of the housing weakened by the notch 104 .
  • Still further advancement of the pusher then releases the device 130 from the housing 100 for deployment of the device 130 at the desired location within the air passageway.
  • the device 130 may be deployed in a controlled manner. Further, the seal of the housing 100 is not broken until the time of deployment, rendering the process sterile.
  • FIGS. 5-7 better illustrate the foregoing process.
  • the pusher 140 has been advanced through the lumen 108 of the extension 106 and has broken through the wall 110 previously separating the housing 100 from the lumen 108 .
  • the pusher includes a disc-shaped end 142 for engaging the device 130 .
  • the pusher 140 may be an appropriately shaped wire or rod.
  • the end 142 may have a diameter dimension slightly less than the diameter dimension of the lumen 108 .
  • the extension 106 may be formed of material flexible enough to permit the end 142 to be slightly greater than the diameter of the lumen 108 . This allows the extension 106 to be slightly deformed as the end 142 of the pusher 140 is advanced down the extension. In either arrangement, the pusher is slidable down the extension to break through the wall 110 and enter the housing 100 .
  • the pusher end 142 As seen in FIG. 6 , once the pusher end 142 is within the housing 100 , it then engages the device 130 upon further distal advancement. The pusher 140 then pushes the device 130 distally to break through the breakaway distal end 102 of the housing 100 .
  • bronchial obstruction devices may be deployed with the present invention. Such devices may be one-way valves, totally blocking, expandable, or non-expandable.
  • FIGS. 8-10 show a complete system 150 embodying the present invention deploying the device 130 within an air passageway, such as bronchial branch sub-branch 48 .
  • the system 150 generally includes the conduit 120 , the housing 100 , the housing extension 106 , and the pusher 140 as previously described.
  • the conduit 120 has been advanced such that its distal end is just proximal to the bronchial sub-branch 48 .
  • the housing 100 has also been advanced through the conduit so that its distal end 102 is within the bronchial sub-branch 48 .
  • the pusher has also been advanced into the housing 100 for engagement with the device 130 .
  • the pusher end 142 is within the housing 100 . It then engages the device 130 and upon further distal advancement, the pusher 140 pushes the device 130 distally to break through the breakaway distal end 102 of the housing 100 .
  • the pusher 140 causes the device 130 to be released from the housing in the bronchial sub-branch 48 . Once released, the device 130 is permitted to expand for deployment in the bronchial sub-branch 48 . Again, the device 130 may be of the type shown and described in the aforementioned U.S. Pat. No. 6,258,100. The now expanded device 130 serves to obstruct the bronchial sub-branch 48 for collapsing the lung portion communicating with the bronchial sub-branch 48 .

Abstract

An apparatus and method deploy a self-expandable bronchial obstruction device in an air passageway. The apparatus includes a catheter configured to be passed down the trachea. The apparatus further includes a capsule for housing the self-expandable bronchial obstruction device in a sterile environment. The capsule is configured to be advanced down the catheter. The capsule further includes a tubular extension. The capsule has a breakable seam so as to release the bronchial obstruction device in the air passageway upon a proximal force being exerted upon the bronchial obstruction device. The method includes guiding a conduit down a trachea into the air passageway. The method further includes advancing a capsule having a bronchial device therein down an internal lumen of the conduit into the air passageway. The method further includes releasing the bronchial device from the capsule. The method further includes deploying the bronchial device into the air passageway.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a continuation of U.S. patent application Ser. No. 11/733,710, filed Apr. 10, 2007, now U.S. Pat. No. 7,896,887 titled APPARATUS AND METHOD FOR DEPLOYMENT OF A BRONCHIAL OBSTRUCTION DEVICE, which is a continuation of U.S. patent application Ser. No. 10/418,929, filed Apr. 17, 2003, titled BRONCHIAL OBSTRUCTION DEVICE DEPLOYMENT SYSTEM AND METHOD, which is a continuation of U.S. patent application Ser. No. 10/052,875, filed on Oct. 25, 2001, now U.S. Pat. No. 6,592,594, titled BRONCHIAL OBSTRUCTION DEVICE DEPLOYMENT SYSTEM AND METHOD. The entire disclosure of each of the above-noted prior applications is hereby incorporated by reference herein and made a part of this specification.
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention is generally directed to a treatment of Chronic Obstructive Pulmonary Disease (COPD). The present invention is more particularly directed to an apparatus and method for deploying a bronchial device.
2. Description of the Related Art
Chronic Obstructive Pulmonary Disease (COPD) has become a major cause of morbidity and mortality in the United States over the last three decades. COPD is characterized by the presence of airflow obstruction due to chronic bronchitis or emphysema. The airflow obstruction in COPD is due largely to structural abnormalities in the smaller airways. Important causes are inflammation, fibrosis, goblet cell metaplasia, and smooth muscle hypertrophy in terminal bronchioles.
The incidence, prevalence, and health-related costs of COPD are on the rise. Mortality due to COPD is also on the rise. In 1991 COPD was the fourth leading cause of death in the United States and has increased 33% since 1979.
COPD affects the patient's whole life. It has three main symptoms: cough; breathlessness; and wheeze. At first, breathlessness may be noticed when running for a bus, digging in the garden, or walking up a hill. Later, it may be noticed when simply walking in the kitchen. Over time, it may occur with less and less effort until it is present all of the time.
COPD is a progressive disease and currently has no cure. Current treatments for COPD include the prevention of further respiratory damage, pharmacotherapy, and surgery. Each is discussed below.
The prevention of further respiratory damage entails the adoption of a healthy lifestyle. Smoking cessation is believed to be the single most important therapeutic intervention. However, regular exercise and weight control are also important. Patients whose symptoms restrict their daily activities or who otherwise have an impaired quality of life may require a pulmonary rehabilitation program including ventilatory muscle training and breathing retraining. Long-term oxygen therapy may also become necessary.
Pharmacotherapy may include bronchodilator therapy to open up the airways as much as possible or inhaled β-agonists. For those patients who respond poorly to the foregoing or who have persistent symptoms, Ipratropium bromide may be indicated. Further, courses of steroids, such as corticosteroids, may be required. Lastly, antibiotics may be required to prevent infections, and influenza and pheumococcal vaccines may be routinely administered. Unfortunately, there is no evidence that early, regular use of pharmacotherapy will alter the progression of COPD.
About 40 years ago, it was first postulated that the tethering force that tends to keep the intrathoracic airways open was lost in emphysema and that by surgically removing the most affected parts of the lungs, the force could be partially restored. Although the surgery was deemed promising, the procedure was abandoned.
The lung volume reduction surgery (LVRS) was later revived. In the early 1990's, hundreds of patients underwent the procedure. However, the procedure has fallen out of favor due to the fact that Medicare stopping reimbursing for LVRS. Unfortunately, data is relatively scarce and many factors conspire to make what data exists difficult to interpret. The procedure is currently under review in a controlled clinical trial. What data does exist tends to indicate that patients benefited from the procedure in terms of an increase in forced expiratory volume, a decrease in total lung capacity, and a significant improvement in lung function, dyspnea, and quality of life. However, the surgery is not without potential complications. Lung tissue is very thin and fragile. Hence, it is difficult to suture after sectioning. This gives rise to potential infection and air leaks. In fact, nearly thirty percent (30%) of such surgeries result in air leaks.
Improvements in pulmonary functions after LVRS have been attributed to at least four possible mechanisms. These include enhanced elastic recoil, correction of ventilation/perfusion mismatch, improved efficiency of respiratory musculature, and improved right ventricular filling.
Lastly, lung transplantation is also an option. Today, COPD is the most common diagnosis for which lung transplantation is considered. Unfortunately, this consideration is given for only those with advanced COPD. Given the limited availability of donor organs, lung transplant is far from being available to all parties.
In view of the need in the art for new and improved therapies for COPD which provide more permanent results than pharmacotherapy while being less invasive and traumatic than LVRS, at least two new therapies have recently been proposed. Both of these new therapies provide lung size reduction by permanently or temporarily collapsing at least a portion of a lung.
In accordance with a first one of these therapies, and as described in U.S. Pat. No. 6,258,100 assigned to the assignee of the present invention and incorporated herein by reference, a lung may be collapsed by obstructing an air passageway communicating with the lung portion to be collapsed. The air passageway may be obstructed by placing a bronchial obstruction device in the air passageway. The bronchial obstruction device may be a plug-like device which precludes air flow in both directions or a one-way valve which permits air to be exhaled from the lung portion to be collapsed while precluding air from being inhaled into the lung portion. Once the air passageway is sealed, the residual air within the lung will be absorbed over time to cause the lung portion to collapse.
As further described in U.S. Pat. No. 6,258,100, the lung portion may be collapsed by inserting a conduit into the air passageway communicating with the lung portion to be collapsed. An obstruction device, such as a one-way valve is then advanced down the conduit into the air passageway. The obstruction device is then deployed in the air passageway for sealing the air passageway and causing the lung portion to be collapsed.
The second therapy is fully described in copending U.S. patent application Ser. No. 09/534,244, filed Mar. 23, 2000, for LUNG CONSTRICTION APPARATUS AND METHOD and is also assigned to the assignee of the present invention. As described therein, a lung constriction device including a sleeve of elastic material is configured to cover at least a portion of a lung. The sleeve has a pair of opened ends to permit the lung portion to be drawn into the sleeve. Once drawn therein, the lung portion is constricted by the sleeve to reduce the size of the lung portion.
Both therapies hold great promise for treating COPD. Neither therapy requires sectioning and suturing of lung tissue.
While either therapy alone would be effective in providing lung size reduction and treatment of COPD, it has recently been proposed that the therapies may be combined for more effective treatment. More specifically, it has been proposed that the therapies could be administered in series, with the first mentioned therapy first applied acutely for evaluation of the effectiveness of lung size reduction in a patient and which lung portions should be reduced in size to obtain the best results. The first therapy is ideal for this as it is noninvasive and could be administered in a physician's office. Once the effectiveness of lung size reduction is confirmed and the identity of the lung portions to be collapsed is determined, the more invasive second mentioned therapy may be administered.
In order to employ the first-mentioned therapy described in U.S. Pat. No. 6,258,100, it is necessary to deploy the bronchial obstruction device within an air passageway. The deployment must be reliable in that the bronchial device must be deployed in a well-controlled manner to assure placement in the proper location. The bronchial device must also be deployed in a sterile manner. Patients suffering from COPD generally have compromised health. Sterile deployment may therefore prevent a catastrophic infection from occurring in those patients who are in a weakened state. The present invention addresses these issues by providing bronchial obstruction device deployment systems and methods which provide more reliable device placement and sterile deployment conditions.
SUMMARY OF THE INVENTION
The present invention provides a device for deploying a self-expandable bronchial obstruction device in an air passageway. The device includes a catheter configured to be passed down the trachea. The device further includes a capsule for housing the self-expandable bronchial obstruction device in a sterile environment. The capsule is further configured to be advanced down the catheter. The capsule further includes a tubular extension. The capsule has a breakable seam so as to release the bronchial device in the air passageway upon a proximal force being exerted upon the bronchial obstruction device. Additionally, the capsule may be formed of flexible material for collapsing within the catheter.
The invention still further provides a method of deploying a bronchial device in an air passageway. The method includes guiding a conduit down a trachea into the air passageway. The method further includes advancing a capsule having a bronchial device therein down an internal lumen of the conduit into the air passageway. The method further includes releasing the bronchial device from the capsule. The method further includes deploying the bronchial device into the air passageway. Additionally, the capsule may comprise a breakable seam from which the bronchial device can be released. The method may further comprise pushing the bronchial device from the capsule.
BRIEF DESCRIPTION OF THE DRAWINGS
The features of the present invention which are believed to be novel are set forth with particularity in the appended claims. The invention, together with further objects and advantages thereof, may best be understood by making reference to the following description taken in conjunction with the accompanying drawings, in the several figures of which like referenced numerals identify identical elements, and wherein:
FIG. 1 is a simplified sectional view of a thorax illustrating a healthy respiratory system;
FIG. 2 is a sectional view similar to FIG. 1, but illustrating a respiratory system suffering from COPD and the execution of a first step in treating the COPD condition in accordance with the present invention;
FIG. 3 is a perspective view, illustrating a housing for the bronchial obstruction device and a conduit embodying the present invention;
FIG. 4 is a partial cross-sectional view of the housing exiting the distal end of the conduit;
FIG. 5 is a side view illustrating a pusher just prior to engaging the bronchial obstruction device;
FIG. 6 is another side view illustrating the device being released from the housing by the pusher;
FIG. 7 is another side view of the device, the housing, and the pusher immediately after the device is released from the housing;
FIG. 8 is a side view illustrating an intermediate step in deploying a bronchial obstruction device in accordance with an embodiment of the present invention;
FIG. 9 is another side view illustrating a further step in the deployment of the device; and
FIG. 10 is a side view illustrating the device after deployment.
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT
Referring now to FIG. 1, it is a sectional view of a healthy respiratory system. The respiratory system 20 resides within the thorax 22 which occupies a space defined by the chest wall 24 and the diaphragm 26.
The respiratory system 20 includes the trachea 28, the left mainstem bronchus 30, the right mainstem bronchus 32, the bronchial branches 34, 36, 38, 40, and 42 and sub-branches 44, 46, 48, and 50. The respiratory system 20 further includes left lung lobes 52 and 54 and right lung lobes 56, 58, and 60. Each bronchial branch and sub-branch communicates with a respective different portion of a lung lobe, either the entire lung lobe or a portion thereof. As used herein, the term “air passageway” is meant to denote either a bronchial branch or sub-branch which communicates with a corresponding individual lung lobe or lung lobe portion to provide inhaled air thereto or conduct exhaled air therefrom.
Characteristic of a healthy respiratory system is the arched or inwardly arcuate diaphragm 26. As the individual inhales, the diaphragm 26 straightens to increase the volume of the thorax 22. This causes a negative pressure within the thorax. The negative pressure within the thorax in turn causes the lung lobes to fill with air. When the individual exhales, the diaphragm returns to its original arched condition to decrease the volume of the thorax. The decreased volume of the thorax causes a positive pressure within the thorax which in turn causes exhalation of the lung lobes.
In contrast to the healthy respiratory system of FIG. 1, FIG. 2 illustrates a respiratory system suffering from COPD. Here it may be seen that the lung lobes 52, 54, 56, 58, and 60 are enlarged and that the diaphragm 26 is not arched but substantially straight. Hence, this individual is incapable of breathing normally by moving the diaphragm 28. Instead, in order to create the negative pressure in the thorax 22 required for breathing, this individual must move the chest wall outwardly to increase the volume of the thorax. This results in inefficient breathing causing these individuals to breathe rapidly with shallow breaths. It has been found that the apex portion 62 and 66 of the upper lung lobes 52 and 56, respectively, are most affected by COPD.
In accordance with the present invention, COPD treatment or evaluation is initiated by feeding a conduit 70 down the trachea 28, into a mainstream bronchus such as the right mainstem bronchus 32, and into an air passageway such as the bronchial branch 42 or the bronchial sub-branch 50. The conduit 70 may be a catheter or a bronchoscope as are well-known in the art. A bronchial obstruction device, contained within a housing, is then advanced down an internal lumen 71 of the conduit 70 and then released from the housing in the air passageway. Once deployed, the obstruction device precludes inhaled air from entering the lung portion to be collapsed. It is preferable that the obstruction device take the form of a one-way valve. In addition to precluding inhaled air from entering the lung portion, the device further allows air within the lung portion to be exhaled. This results in more rapid collapse of the lung portion. However, obstruction devices which preclude both inhaled and exhaled air flow may be deployed by the apparatus and method of the invention.
FIGS. 3 and 4 show a bronchial obstruction device housing 100 and a conduit 120 embodying the present invention. The housing 100 forms a sealed capsule structure for housing a bronchial obstruction device 130 to be deployed within an air passageway. The housing 100 has a rounded distal end 102. The rounded configuration of the distal end 102 assists in the guiding of the housing to a desired location within the air passageway. The housing 100, as best seen in FIG. 4 is formed of a flexible, biocompatible material for collapsing within the internal lumen 122 of the conduit 120 as it is advanced through the conduit.
The housing distal end 102 further includes a score or notch 104 to enable the distal end 104 of the housing 100 to be broken-away during deployment of the device 130 without breaking the seal within the housing 100 until the time of deployment.
The housing still further includes a tubular extension 106 having an internal lumen 108. The lumen 108 communicates with the interior of the housing 100 during deployment of the device 130 but may be separated therefrom by a breakable wall 110. As will be seen subsequently, the breakable wall 110 maintains the seal of the housing while permitting a pusher to be advanced through the lumen 108 to break through the wall 110 at the time of deployment to then engage the device 130. With the device 130 thus engaged, further distal advancement of the pusher causes the device to break through the distal end 102 of the housing weakened by the notch 104. Still further advancement of the pusher then releases the device 130 from the housing 100 for deployment of the device 130 at the desired location within the air passageway.
Hence, the device 130 may be deployed in a controlled manner. Further, the seal of the housing 100 is not broken until the time of deployment, rendering the process sterile.
FIGS. 5-7 better illustrate the foregoing process. In FIG. 5 it may be seen that the pusher 140 has been advanced through the lumen 108 of the extension 106 and has broken through the wall 110 previously separating the housing 100 from the lumen 108. In accordance with this embodiment, the pusher includes a disc-shaped end 142 for engaging the device 130. Alternatively, the pusher 140 may be an appropriately shaped wire or rod. The end 142 may have a diameter dimension slightly less than the diameter dimension of the lumen 108. Alternatively, the extension 106 may be formed of material flexible enough to permit the end 142 to be slightly greater than the diameter of the lumen 108. This allows the extension 106 to be slightly deformed as the end 142 of the pusher 140 is advanced down the extension. In either arrangement, the pusher is slidable down the extension to break through the wall 110 and enter the housing 100.
As seen in FIG. 6, once the pusher end 142 is within the housing 100, it then engages the device 130 upon further distal advancement. The pusher 140 then pushes the device 130 distally to break through the breakaway distal end 102 of the housing 100.
Further advancement of the pusher 140 causes the device 130 to be released from the housing. Once released, the device 130 is permitted to expand for deployment. Such a device is shown and described in the aforementioned U.S. Pat. No. 6,258,100. As previously mentioned, other forms of bronchial obstruction devices may be deployed with the present invention. Such devices may be one-way valves, totally blocking, expandable, or non-expandable.
FIGS. 8-10 show a complete system 150 embodying the present invention deploying the device 130 within an air passageway, such as bronchial branch sub-branch 48. The system 150 generally includes the conduit 120, the housing 100, the housing extension 106, and the pusher 140 as previously described. In FIG. 8 it may be seen that the conduit 120 has been advanced such that its distal end is just proximal to the bronchial sub-branch 48. The housing 100 has also been advanced through the conduit so that its distal end 102 is within the bronchial sub-branch 48. The pusher has also been advanced into the housing 100 for engagement with the device 130.
As seen in FIG. 9, the pusher end 142 is within the housing 100. It then engages the device 130 and upon further distal advancement, the pusher 140 pushes the device 130 distally to break through the breakaway distal end 102 of the housing 100.
Further advancement of the pusher 140 causes the device 130 to be released from the housing in the bronchial sub-branch 48. Once released, the device 130 is permitted to expand for deployment in the bronchial sub-branch 48. Again, the device 130 may be of the type shown and described in the aforementioned U.S. Pat. No. 6,258,100. The now expanded device 130 serves to obstruct the bronchial sub-branch 48 for collapsing the lung portion communicating with the bronchial sub-branch 48.
Although the invention(s) presented herein have been disclosed in the context of certain preferred embodiments and examples, it will be understood by those skilled in the art that the invention(s) extend beyond the specifically disclosed embodiments to other alternative embodiments and/or uses of the invention(s) and obvious modifications and equivalents thereof. Thus, it is intended that the scope of the invention(s) herein disclosed should not be limited by the particular embodiments described above, but should be determined only by a fair reading of the claims that follow.

Claims (19)

What is claimed is:
1. An apparatus for deploying a bronchial device in an air passageway, the apparatus comprising:
a conduit configured to be passed down a trachea, the conduit comprising an internal lumen,
an axially-movable push rod within the internal lumen,
a housing that defines a sealed capsule that is movable relative to the conduit, the sealed capsule substantially sealingly enclosing and separating the bronchial device from an environment external to the capsule, the bronchial device positioned within the housing, and
the housing being further arranged to be advanced down the internal lumen of the conduit placed into the air passageway in the direction of a distal end of the housing and, upon movement of the axially-movable push rod from outside of the capsule into a proximal end of the sealed capsule and upon application of force by the axially-movable push rod on a proximal end of the bronchial device, the bronchial device is released through a distal end of the capsule for deployment in the air passageway such that the bronchial device is not in physical contact with the housing or the conduit once deployed.
2. The apparatus of claim 1, wherein the housing further comprises an openable feature through which the bronchial device is released.
3. The apparatus of claim 2, wherein the openable feature is opened by being broken.
4. The apparatus of claim 1, wherein the housing comprises a break-away portion through which the axially-movable push rod extends to contact the bronchial device.
5. The apparatus of claim 1, wherein the sealed capsule comprises an openable feature at one end and a break-away feature at a second end.
6. The apparatus of claim 5, wherein the push rod can break through the break-away feature to urge the bronchial device through the openable feature.
7. The apparatus of claim 1, wherein the push rod extends within a lumen defined within a tubular extension attached to the housing.
8. The apparatus of claim 7, wherein the tubular extension is configured to deform as the axially-movable push rod is advanced through the tubular extension.
9. The apparatus of claim 1, wherein the housing includes a flexible material for collapsing within an internal lumen of the conduit.
10. The apparatus of claim 1, wherein the axially-movable push rod is located outside of the capsule until the application of force onto the proximal end of the capsule.
11. The apparatus of claim 1, wherein the capsule is configured to be fully within the conduit.
12. The apparatus of claim 1, wherein the capsule is configured to be broken on both the proximal and distal ends.
13. The apparatus of claim 12, wherein upon movement of the axially-movable push rod from outside of the capsule, the axially-movable push rod breaks the proximal end of the capsule, contacts the bronchial device at a proximal end, and pushes against the proximal end of the bronchial device so that a distal end of the bronchial device breaks the distal end of the capsule.
14. The apparatus of claim 1, wherein the sealed capsule is located distal of the distal end of the axially-movable push rod prior to movement of the axially-movable push rod from outside of the sealed capsule into a proximal end of the sealed capsule.
15. A system for deploying a bronchial device in an air passageway, the system comprising:
a catheter configured to be passed down a trachea, into a bronchus communicating with the trachea and into the air passageway communicating with the lung portion, the catheter comprising an internal lumen;
an axially-movable pusher within the internal lumen;
a housing that defines a sealed capsule arranged to substantially sealingly encapsulate and separate the bronchial device from an environment external to the capsule, the housing configured to be fully within the catheter; the pusher movable relative to the housing the bronchial device positioned within the sealed capsule, the housing being further arranged to be advanced down an internal lumen of the catheter placed into the air passageway in the direction of a distal end of the catheter, and to release the bronchial device, upon movement of the axially-movable pusher from outside of the capsule into a proximal end of the sealed capsule and upon application of a force on a proximal end of the bronchial device, for deployment through a distal end of the sealed capsule in the air passageway such that the bronchial device is not in physical contact with the housing or the catheter once deployed, the axially-movable pusher being located outside of the sealed capsule until the application of the force on the proximal end of the sealed capsule; and
the housing comprising a proximally extending tubular extension that is separated from the bronchial device by a wall defining the sealed capsule.
16. The system of claim 15, wherein the housing further comprises an openable end through which the bronchial device is released.
17. The system of claim 16, wherein the wall is breakable to place an inside of the capsule into communication with a lumen defined by the tubular extension.
18. The system of claim 15, wherein the housing comprises a break-away portion arranged upon breakage to release the bronchial device.
19. The apparatus of claim 15, wherein upon movement of the axially-movable pusher from outside of the capsule, the axially-movable pusher breaks the proximal end of the capsule, contacts the bronchial device at a proximal end, and pushes against the proximal end of the bronchial device so that a distal end of the bronchial device breaks the distal end of the housing.
US13/013,070 2001-10-25 2011-01-25 Apparatus and method for deployment of a bronchial obstruction device Expired - Fee Related US8986336B2 (en)

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US14/665,221 US20160015949A1 (en) 2001-10-25 2015-03-23 Apparatus and method for deployment of a bronchial obstruction device

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US10/052,875 US6592594B2 (en) 2001-10-25 2001-10-25 Bronchial obstruction device deployment system and method
US10/418,929 US20030183235A1 (en) 2001-10-25 2003-04-17 Bronchial obstruction device deployment system and method
US11/733,710 US7896887B2 (en) 2001-10-25 2007-04-10 Apparatus and method for deployment of a bronchial obstruction device
US13/013,070 US8986336B2 (en) 2001-10-25 2011-01-25 Apparatus and method for deployment of a bronchial obstruction device

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US11/733,710 Expired - Fee Related US7896887B2 (en) 2001-10-25 2007-04-10 Apparatus and method for deployment of a bronchial obstruction device
US13/013,070 Expired - Fee Related US8986336B2 (en) 2001-10-25 2011-01-25 Apparatus and method for deployment of a bronchial obstruction device
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9198669B2 (en) 2006-03-31 2015-12-01 Spiration, Inc. Articulable anchor
US9622752B2 (en) 2003-08-08 2017-04-18 Spiration, Inc. Bronchoscopic repair of air leaks in a lung
US10470839B2 (en) 2016-06-02 2019-11-12 Covidien Lp Assessment of suture or staple line integrity and localization of potential tissue defects along the suture or staple line

Families Citing this family (225)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5954766A (en) * 1997-09-16 1999-09-21 Zadno-Azizi; Gholam-Reza Body fluid flow control device
US8016823B2 (en) 2003-01-18 2011-09-13 Tsunami Medtech, Llc Medical instrument and method of use
US7892229B2 (en) 2003-01-18 2011-02-22 Tsunami Medtech, Llc Medical instruments and techniques for treating pulmonary disorders
US6997189B2 (en) * 1998-06-05 2006-02-14 Broncus Technologies, Inc. Method for lung volume reduction
US7654998B1 (en) 1999-08-23 2010-02-02 Aeris Therapeutics, Inc. Tissue volume reduction
US6610043B1 (en) 1999-08-23 2003-08-26 Bistech, Inc. Tissue volume reduction
US20030070683A1 (en) * 2000-03-04 2003-04-17 Deem Mark E. Methods and devices for use in performing pulmonary procedures
US6679264B1 (en) 2000-03-04 2004-01-20 Emphasys Medical, Inc. Methods and devices for use in performing pulmonary procedures
US8474460B2 (en) 2000-03-04 2013-07-02 Pulmonx Corporation Implanted bronchial isolation devices and methods
US6722360B2 (en) 2000-06-16 2004-04-20 Rajiv Doshi Methods and devices for improving breathing in patients with pulmonary disease
US7549987B2 (en) 2000-12-09 2009-06-23 Tsunami Medtech, Llc Thermotherapy device
US9433457B2 (en) 2000-12-09 2016-09-06 Tsunami Medtech, Llc Medical instruments and techniques for thermally-mediated therapies
US20040074491A1 (en) * 2001-03-02 2004-04-22 Michael Hendricksen Delivery methods and devices for implantable bronchial isolation devices
US7798147B2 (en) 2001-03-02 2010-09-21 Pulmonx Corporation Bronchial flow control devices with membrane seal
US7011094B2 (en) * 2001-03-02 2006-03-14 Emphasys Medical, Inc. Bronchial flow control devices and methods of use
US6994706B2 (en) 2001-08-13 2006-02-07 Minnesota Medical Physics, Llc Apparatus and method for treatment of benign prostatic hyperplasia
US20030050648A1 (en) 2001-09-11 2003-03-13 Spiration, Inc. Removable lung reduction devices, systems, and methods
EP1434615B1 (en) * 2001-10-11 2007-07-11 Emphasys Medical, Inc. Bronchial flow control device
US6592594B2 (en) 2001-10-25 2003-07-15 Spiration, Inc. Bronchial obstruction device deployment system and method
US8444636B2 (en) 2001-12-07 2013-05-21 Tsunami Medtech, Llc Medical instrument and method of use
US6929637B2 (en) * 2002-02-21 2005-08-16 Spiration, Inc. Device and method for intra-bronchial provision of a therapeutic agent
US20030154988A1 (en) * 2002-02-21 2003-08-21 Spiration, Inc. Intra-bronchial device that provides a medicant intra-bronchially to the patient
WO2003075796A2 (en) * 2002-03-08 2003-09-18 Emphasys Medical, Inc. Methods and devices for inducing collapse in lung regions fed by collateral pathways
US20030216769A1 (en) 2002-05-17 2003-11-20 Dillard David H. Removable anchored lung volume reduction devices and methods
US20030181922A1 (en) 2002-03-20 2003-09-25 Spiration, Inc. Removable anchored lung volume reduction devices and methods
US20030195385A1 (en) * 2002-04-16 2003-10-16 Spiration, Inc. Removable anchored lung volume reduction devices and methods
US20030212412A1 (en) * 2002-05-09 2003-11-13 Spiration, Inc. Intra-bronchial obstructing device that permits mucus transport
US20040039250A1 (en) * 2002-05-28 2004-02-26 David Tholfsen Guidewire delivery of implantable bronchial isolation devices in accordance with lung treatment
US20040059263A1 (en) * 2002-09-24 2004-03-25 Spiration, Inc. Device and method for measuring the diameter of an air passageway
US20040010209A1 (en) * 2002-07-15 2004-01-15 Spiration, Inc. Device and method for measuring the diameter of an air passageway
EP1524942B1 (en) 2002-07-26 2008-09-10 Emphasys Medical, Inc. Bronchial flow control devices with membrane seal
DE60329625D1 (en) * 2002-11-27 2009-11-19 Pulmonx Corp INTRODUCTION FOR IMPLANTABLE BRONCHIAL INSULATION DEVICES
US7814912B2 (en) * 2002-11-27 2010-10-19 Pulmonx Corporation Delivery methods and devices for implantable bronchial isolation devices
US20040210248A1 (en) * 2003-03-12 2004-10-21 Spiration, Inc. Apparatus, method and assembly for delivery of intra-bronchial devices
US7100616B2 (en) * 2003-04-08 2006-09-05 Spiration, Inc. Bronchoscopic lung volume reduction method
US7811274B2 (en) 2003-05-07 2010-10-12 Portaero, Inc. Method for treating chronic obstructive pulmonary disease
US7426929B2 (en) 2003-05-20 2008-09-23 Portaero, Inc. Intra/extra-thoracic collateral ventilation bypass system and method
US7200559B2 (en) * 2003-05-29 2007-04-03 Microsoft Corporation Semantic object synchronous understanding implemented with speech application language tags
US7252086B2 (en) 2003-06-03 2007-08-07 Cordis Corporation Lung reduction system
US7377278B2 (en) 2003-06-05 2008-05-27 Portaero, Inc. Intra-thoracic collateral ventilation bypass system and method
US7682332B2 (en) 2003-07-15 2010-03-23 Portaero, Inc. Methods to accelerate wound healing in thoracic anastomosis applications
US8579892B2 (en) 2003-10-07 2013-11-12 Tsunami Medtech, Llc Medical system and method of use
US20050178389A1 (en) * 2004-01-27 2005-08-18 Shaw David P. Disease indications for selective endobronchial lung region isolation
US8206684B2 (en) 2004-02-27 2012-06-26 Pulmonx Corporation Methods and devices for blocking flow through collateral pathways in the lung
EP2368525B1 (en) * 2004-03-08 2019-09-18 Pulmonx, Inc Implanted bronchial isolation devices
US7775968B2 (en) 2004-06-14 2010-08-17 Pneumrx, Inc. Guided access to lung tissues
US7766891B2 (en) 2004-07-08 2010-08-03 Pneumrx, Inc. Lung device with sealing features
WO2006014567A2 (en) 2004-07-08 2006-02-09 Pneumrx, Inc. Pleural effusion treatment device, method and material
US20060030863A1 (en) * 2004-07-21 2006-02-09 Fields Antony J Implanted bronchial isolation device delivery devices and methods
US20060047291A1 (en) * 2004-08-20 2006-03-02 Uptake Medical Corporation Non-foreign occlusion of an airway and lung collapse
EP1793744B1 (en) 2004-09-22 2008-12-17 Dendron GmbH Medical implant
US8845676B2 (en) 2004-09-22 2014-09-30 Micro Therapeutics Micro-spiral implantation device
ES2645340T3 (en) 2004-11-16 2017-12-05 Uptake Medical Technology Inc. Lung treatment device
WO2006055047A2 (en) * 2004-11-18 2006-05-26 Mark Adler Intra-bronchial apparatus for aspiration and insufflation of lung regions distal to placement or cross communication and deployment and placement system therefor
US7771472B2 (en) 2004-11-19 2010-08-10 Pulmonx Corporation Bronchial flow control devices and methods of use
US8220460B2 (en) 2004-11-19 2012-07-17 Portaero, Inc. Evacuation device and method for creating a localized pleurodesis
EP1816945B1 (en) 2004-11-23 2019-08-21 PneumRx, Inc. Steerable device for accessing a target site
US10610228B2 (en) 2004-12-08 2020-04-07 Theravent, Inc. Passive nasal peep devices
US9833354B2 (en) 2004-12-08 2017-12-05 Theravent, Inc. Nasal respiratory devices
US7806120B2 (en) 2004-12-08 2010-10-05 Ventus Medical, Inc. Nasal respiratory devices for positive end-expiratory pressure
US8061357B2 (en) 2004-12-08 2011-11-22 Ventus Medical, Inc. Adhesive nasal respiratory devices
WO2006063339A2 (en) 2004-12-08 2006-06-15 Ventus Medical, Inc. Respiratory devices and methods of use
US7824366B2 (en) 2004-12-10 2010-11-02 Portaero, Inc. Collateral ventilation device with chest tube/evacuation features and method
US8876791B2 (en) 2005-02-25 2014-11-04 Pulmonx Corporation Collateral pathway treatment using agent entrained by aspiration flow current
US20070032785A1 (en) 2005-08-03 2007-02-08 Jennifer Diederich Tissue evacuation device
US8104474B2 (en) 2005-08-23 2012-01-31 Portaero, Inc. Collateral ventilation bypass system with retention features
WO2007035798A2 (en) 2005-09-19 2007-03-29 Calypso Medical Technologies, Inc. Apparatus and methods for implanting objects, such as bronchoscopically implanting markers in the lung of patients
US7406963B2 (en) 2006-01-17 2008-08-05 Portaero, Inc. Variable resistance pulmonary ventilation bypass valve and method
US7625392B2 (en) * 2006-02-03 2009-12-01 James Coleman Wound closure devices and methods
US8157837B2 (en) 2006-03-13 2012-04-17 Pneumrx, Inc. Minimally invasive lung volume reduction device and method
US8721734B2 (en) 2009-05-18 2014-05-13 Pneumrx, Inc. Cross-sectional modification during deployment of an elongate lung volume reduction device
US8888800B2 (en) 2006-03-13 2014-11-18 Pneumrx, Inc. Lung volume reduction devices, methods, and systems
US9402633B2 (en) 2006-03-13 2016-08-02 Pneumrx, Inc. Torque alleviating intra-airway lung volume reduction compressive implant structures
US7829986B2 (en) * 2006-04-01 2010-11-09 Stats Chippac Ltd. Integrated circuit package system with net spacer
KR20090008347A (en) 2006-04-17 2009-01-21 마이크로 테라퓨틱스 인코포레이티드 System and method for mechanically positioning intravascular implants
GB0610171D0 (en) 2006-05-23 2006-06-28 Robitaille Jean Pierre Valved nasal canula
EP2026723B1 (en) 2006-05-23 2018-11-21 Theravent, Inc. Nasal respiratory devices
EP2032213A4 (en) 2006-06-07 2014-02-19 Theravent Inc Nasal devices
US7993323B2 (en) 2006-11-13 2011-08-09 Uptake Medical Corp. High pressure and high temperature vapor catheters and systems
US8585645B2 (en) * 2006-11-13 2013-11-19 Uptake Medical Corp. Treatment with high temperature vapor
US8240309B2 (en) * 2006-11-16 2012-08-14 Ventus Medical, Inc. Adjustable nasal devices
US7655004B2 (en) 2007-02-15 2010-02-02 Ethicon Endo-Surgery, Inc. Electroporation ablation apparatus, system, and method
US8328860B2 (en) 2007-03-13 2012-12-11 Covidien Lp Implant including a coil and a stretch-resistant member
WO2008115922A1 (en) 2007-03-19 2008-09-25 Michael Brenzel Methods and apparatus for occlusion of body lumens
US8075572B2 (en) 2007-04-26 2011-12-13 Ethicon Endo-Surgery, Inc. Surgical suturing apparatus
US8163034B2 (en) 2007-05-11 2012-04-24 Portaero, Inc. Methods and devices to create a chemically and/or mechanically localized pleurodesis
US7931641B2 (en) 2007-05-11 2011-04-26 Portaero, Inc. Visceral pleura ring connector
US8062315B2 (en) 2007-05-17 2011-11-22 Portaero, Inc. Variable parietal/visceral pleural coupling
ATE556667T1 (en) 2007-08-23 2012-05-15 Aegea Medical Inc UTERUS THERAPY DEVICE
US8568410B2 (en) 2007-08-31 2013-10-29 Ethicon Endo-Surgery, Inc. Electrical ablation surgical instruments
US8262655B2 (en) 2007-11-21 2012-09-11 Ethicon Endo-Surgery, Inc. Bipolar forceps
US8579897B2 (en) 2007-11-21 2013-11-12 Ethicon Endo-Surgery, Inc. Bipolar forceps
US8136230B2 (en) 2007-10-12 2012-03-20 Spiration, Inc. Valve loader method, system, and apparatus
US8043301B2 (en) 2007-10-12 2011-10-25 Spiration, Inc. Valve loader method, system, and apparatus
US9301761B2 (en) 2007-10-22 2016-04-05 James E. Coleman Anastomosis devices and methods
WO2009055410A1 (en) * 2007-10-22 2009-04-30 Uptake Medical Corp. Determining patient-specific vapor treatment and delivery parameters
US8322335B2 (en) * 2007-10-22 2012-12-04 Uptake Medical Corp. Determining patient-specific vapor treatment and delivery parameters
US8480657B2 (en) 2007-10-31 2013-07-09 Ethicon Endo-Surgery, Inc. Detachable distal overtube section and methods for forming a sealable opening in the wall of an organ
US20090112059A1 (en) 2007-10-31 2009-04-30 Nobis Rudolph H Apparatus and methods for closing a gastrotomy
US8020700B2 (en) 2007-12-05 2011-09-20 Ventus Medical, Inc. Packaging and dispensing nasal devices
WO2009105432A2 (en) 2008-02-19 2009-08-27 Portaero, Inc. Devices and methods for delivery of a therapeutic agent through a pneumostoma
US8336540B2 (en) 2008-02-19 2012-12-25 Portaero, Inc. Pneumostoma management device and method for treatment of chronic obstructive pulmonary disease
US8475389B2 (en) 2008-02-19 2013-07-02 Portaero, Inc. Methods and devices for assessment of pneumostoma function
US9924992B2 (en) 2008-02-20 2018-03-27 Tsunami Medtech, Llc Medical system and method of use
US8262680B2 (en) 2008-03-10 2012-09-11 Ethicon Endo-Surgery, Inc. Anastomotic device
US9283051B2 (en) 2008-04-29 2016-03-15 Virginia Tech Intellectual Properties, Inc. System and method for estimating a treatment volume for administering electrical-energy based therapies
US8992517B2 (en) 2008-04-29 2015-03-31 Virginia Tech Intellectual Properties Inc. Irreversible electroporation to treat aberrant cell masses
US10238447B2 (en) 2008-04-29 2019-03-26 Virginia Tech Intellectual Properties, Inc. System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress
US10117707B2 (en) 2008-04-29 2018-11-06 Virginia Tech Intellectual Properties, Inc. System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
US9598691B2 (en) 2008-04-29 2017-03-21 Virginia Tech Intellectual Properties, Inc. Irreversible electroporation to create tissue scaffolds
US9867652B2 (en) 2008-04-29 2018-01-16 Virginia Tech Intellectual Properties, Inc. Irreversible electroporation using tissue vasculature to treat aberrant cell masses or create tissue scaffolds
US10448989B2 (en) 2009-04-09 2019-10-22 Virginia Tech Intellectual Properties, Inc. High-frequency electroporation for cancer therapy
US11254926B2 (en) 2008-04-29 2022-02-22 Virginia Tech Intellectual Properties, Inc. Devices and methods for high frequency electroporation
US10272178B2 (en) 2008-04-29 2019-04-30 Virginia Tech Intellectual Properties Inc. Methods for blood-brain barrier disruption using electrical energy
US10702326B2 (en) 2011-07-15 2020-07-07 Virginia Tech Intellectual Properties, Inc. Device and method for electroporation based treatment of stenosis of a tubular body part
US9198733B2 (en) 2008-04-29 2015-12-01 Virginia Tech Intellectual Properties, Inc. Treatment planning for electroporation-based therapies
US11272979B2 (en) 2008-04-29 2022-03-15 Virginia Tech Intellectual Properties, Inc. System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
US10245098B2 (en) 2008-04-29 2019-04-02 Virginia Tech Intellectual Properties, Inc. Acute blood-brain barrier disruption using electrical energy based therapy
US8652150B2 (en) 2008-05-30 2014-02-18 Ethicon Endo-Surgery, Inc. Multifunction surgical device
US8070759B2 (en) 2008-05-30 2011-12-06 Ethicon Endo-Surgery, Inc. Surgical fastening device
US8679003B2 (en) 2008-05-30 2014-03-25 Ethicon Endo-Surgery, Inc. Surgical device and endoscope including same
US8317806B2 (en) 2008-05-30 2012-11-27 Ethicon Endo-Surgery, Inc. Endoscopic suturing tension controlling and indication devices
US8771260B2 (en) 2008-05-30 2014-07-08 Ethicon Endo-Surgery, Inc. Actuating and articulating surgical device
US8114072B2 (en) 2008-05-30 2012-02-14 Ethicon Endo-Surgery, Inc. Electrical ablation device
US8721632B2 (en) 2008-09-09 2014-05-13 Tsunami Medtech, Llc Methods for delivering energy into a target tissue of a body
US8906035B2 (en) 2008-06-04 2014-12-09 Ethicon Endo-Surgery, Inc. Endoscopic drop off bag
US8403926B2 (en) 2008-06-05 2013-03-26 Ethicon Endo-Surgery, Inc. Manually articulating devices
US8579888B2 (en) 2008-06-17 2013-11-12 Tsunami Medtech, Llc Medical probes for the treatment of blood vessels
US8361112B2 (en) 2008-06-27 2013-01-29 Ethicon Endo-Surgery, Inc. Surgical suture arrangement
US8262563B2 (en) 2008-07-14 2012-09-11 Ethicon Endo-Surgery, Inc. Endoscopic translumenal articulatable steerable overtube
US8888792B2 (en) 2008-07-14 2014-11-18 Ethicon Endo-Surgery, Inc. Tissue apposition clip application devices and methods
US8211125B2 (en) * 2008-08-15 2012-07-03 Ethicon Endo-Surgery, Inc. Sterile appliance delivery device for endoscopic procedures
US8529563B2 (en) 2008-08-25 2013-09-10 Ethicon Endo-Surgery, Inc. Electrical ablation devices
US8241204B2 (en) 2008-08-29 2012-08-14 Ethicon Endo-Surgery, Inc. Articulating end cap
US8480689B2 (en) 2008-09-02 2013-07-09 Ethicon Endo-Surgery, Inc. Suturing device
US8409200B2 (en) 2008-09-03 2013-04-02 Ethicon Endo-Surgery, Inc. Surgical grasping device
US8114119B2 (en) 2008-09-09 2012-02-14 Ethicon Endo-Surgery, Inc. Surgical grasping device
US8632605B2 (en) 2008-09-12 2014-01-21 Pneumrx, Inc. Elongated lung volume reduction devices, methods, and systems
US8337394B2 (en) 2008-10-01 2012-12-25 Ethicon Endo-Surgery, Inc. Overtube with expandable tip
US10695126B2 (en) 2008-10-06 2020-06-30 Santa Anna Tech Llc Catheter with a double balloon structure to generate and apply a heated ablative zone to tissue
US9561066B2 (en) 2008-10-06 2017-02-07 Virender K. Sharma Method and apparatus for tissue ablation
EP2341859B1 (en) 2008-10-06 2017-04-05 Virender K. Sharma Apparatus for tissue ablation
US10064697B2 (en) 2008-10-06 2018-09-04 Santa Anna Tech Llc Vapor based ablation system for treating various indications
US9561068B2 (en) 2008-10-06 2017-02-07 Virender K. Sharma Method and apparatus for tissue ablation
US8197498B2 (en) 2008-11-06 2012-06-12 Trinitas Ventures Ltd. Gastric bypass devices and procedures
US8157834B2 (en) 2008-11-25 2012-04-17 Ethicon Endo-Surgery, Inc. Rotational coupling device for surgical instrument with flexible actuators
US8172772B2 (en) 2008-12-11 2012-05-08 Ethicon Endo-Surgery, Inc. Specimen retrieval device
US8347881B2 (en) 2009-01-08 2013-01-08 Portaero, Inc. Pneumostoma management device with integrated patency sensor and method
US8361066B2 (en) 2009-01-12 2013-01-29 Ethicon Endo-Surgery, Inc. Electrical ablation devices
US8828031B2 (en) 2009-01-12 2014-09-09 Ethicon Endo-Surgery, Inc. Apparatus for forming an anastomosis
US8252057B2 (en) 2009-01-30 2012-08-28 Ethicon Endo-Surgery, Inc. Surgical access device
US9226772B2 (en) 2009-01-30 2016-01-05 Ethicon Endo-Surgery, Inc. Surgical device
US11284931B2 (en) 2009-02-03 2022-03-29 Tsunami Medtech, Llc Medical systems and methods for ablating and absorbing tissue
US8518053B2 (en) 2009-02-11 2013-08-27 Portaero, Inc. Surgical instruments for creating a pneumostoma and treating chronic obstructive pulmonary disease
US11638603B2 (en) 2009-04-09 2023-05-02 Virginia Tech Intellectual Properties, Inc. Selective modulation of intracellular effects of cells using pulsed electric fields
US11382681B2 (en) 2009-04-09 2022-07-12 Virginia Tech Intellectual Properties, Inc. Device and methods for delivery of high frequency electrical pulses for non-thermal ablation
US8903488B2 (en) 2009-05-28 2014-12-02 Angiodynamics, Inc. System and method for synchronizing energy delivery to the cardiac rhythm
US9895189B2 (en) 2009-06-19 2018-02-20 Angiodynamics, Inc. Methods of sterilization and treating infection using irreversible electroporation
US20110093009A1 (en) * 2009-10-16 2011-04-21 Ethicon Endo-Surgery, Inc. Otomy closure device
US20110098704A1 (en) 2009-10-28 2011-04-28 Ethicon Endo-Surgery, Inc. Electrical ablation devices
US8608652B2 (en) 2009-11-05 2013-12-17 Ethicon Endo-Surgery, Inc. Vaginal entry surgical devices, kit, system, and method
US8900223B2 (en) 2009-11-06 2014-12-02 Tsunami Medtech, Llc Tissue ablation systems and methods of use
US8353487B2 (en) * 2009-12-17 2013-01-15 Ethicon Endo-Surgery, Inc. User interface support devices for endoscopic surgical instruments
US8496574B2 (en) 2009-12-17 2013-07-30 Ethicon Endo-Surgery, Inc. Selectively positionable camera for surgical guide tube assembly
US8506564B2 (en) 2009-12-18 2013-08-13 Ethicon Endo-Surgery, Inc. Surgical instrument comprising an electrode
US9028483B2 (en) 2009-12-18 2015-05-12 Ethicon Endo-Surgery, Inc. Surgical instrument comprising an electrode
US9161801B2 (en) 2009-12-30 2015-10-20 Tsunami Medtech, Llc Medical system and method of use
US9005198B2 (en) 2010-01-29 2015-04-14 Ethicon Endo-Surgery, Inc. Surgical instrument comprising an electrode
US8425455B2 (en) 2010-03-30 2013-04-23 Angiodynamics, Inc. Bronchial catheter and method of use
US8875711B2 (en) 2010-05-27 2014-11-04 Theravent, Inc. Layered nasal respiratory devices
US9943353B2 (en) 2013-03-15 2018-04-17 Tsunami Medtech, Llc Medical system and method of use
ES2912362T3 (en) 2010-11-09 2022-05-25 Aegea Medical Inc Method of placement and apparatus for delivering steam to the uterus
US10092291B2 (en) 2011-01-25 2018-10-09 Ethicon Endo-Surgery, Inc. Surgical instrument with selectively rigidizable features
US9254169B2 (en) 2011-02-28 2016-02-09 Ethicon Endo-Surgery, Inc. Electrical ablation devices and methods
US9233241B2 (en) 2011-02-28 2016-01-12 Ethicon Endo-Surgery, Inc. Electrical ablation devices and methods
US9314620B2 (en) 2011-02-28 2016-04-19 Ethicon Endo-Surgery, Inc. Electrical ablation devices and methods
US9049987B2 (en) 2011-03-17 2015-06-09 Ethicon Endo-Surgery, Inc. Hand held surgical device for manipulating an internal magnet assembly within a patient
US8795241B2 (en) 2011-05-13 2014-08-05 Spiration, Inc. Deployment catheter
EP2758010B1 (en) 2011-09-23 2017-02-08 Pulmonx, Inc Implant loading system
US9078665B2 (en) 2011-09-28 2015-07-14 Angiodynamics, Inc. Multiple treatment zone ablation probe
US9730830B2 (en) 2011-09-29 2017-08-15 Trudell Medical International Nasal insert and cannula and methods for the use thereof
CN104135960B (en) 2011-10-07 2017-06-06 埃杰亚医疗公司 A kind of uterine therapy device
US9579104B2 (en) 2011-11-30 2017-02-28 Covidien Lp Positioning and detaching implants
US9247930B2 (en) 2011-12-21 2016-02-02 James E. Coleman Devices and methods for occluding or promoting fluid flow
US9011480B2 (en) 2012-01-20 2015-04-21 Covidien Lp Aneurysm treatment coils
US8986199B2 (en) 2012-02-17 2015-03-24 Ethicon Endo-Surgery, Inc. Apparatus and methods for cleaning the lens of an endoscope
US9687245B2 (en) 2012-03-23 2017-06-27 Covidien Lp Occlusive devices and methods of use
US9427255B2 (en) 2012-05-14 2016-08-30 Ethicon Endo-Surgery, Inc. Apparatus for introducing a steerable camera assembly into a patient
US9078662B2 (en) 2012-07-03 2015-07-14 Ethicon Endo-Surgery, Inc. Endoscopic cap electrode and method for using the same
US9545290B2 (en) 2012-07-30 2017-01-17 Ethicon Endo-Surgery, Inc. Needle probe guide
US9572623B2 (en) 2012-08-02 2017-02-21 Ethicon Endo-Surgery, Inc. Reusable electrode and disposable sheath
US10314649B2 (en) 2012-08-02 2019-06-11 Ethicon Endo-Surgery, Inc. Flexible expandable electrode and method of intraluminal delivery of pulsed power
US9277957B2 (en) 2012-08-15 2016-03-08 Ethicon Endo-Surgery, Inc. Electrosurgical devices and methods
EP3964151A3 (en) 2013-01-17 2022-03-30 Virender K. Sharma Apparatus for tissue ablation
US10098527B2 (en) 2013-02-27 2018-10-16 Ethidcon Endo-Surgery, Inc. System for performing a minimally invasive surgical procedure
JP6329240B2 (en) 2013-03-14 2018-05-23 スパイレーション インコーポレイテッド ディー ビー エイ オリンパス レスピラトリー アメリカ Valve loader method, system, and apparatus
US9782211B2 (en) 2013-10-01 2017-10-10 Uptake Medical Technology Inc. Preferential volume reduction of diseased segments of a heterogeneous lobe
US9713475B2 (en) 2014-04-18 2017-07-25 Covidien Lp Embolic medical devices
JP6594901B2 (en) 2014-05-12 2019-10-23 バージニア テック インテレクチュアル プロパティース インコーポレイテッド Selective modulation of intracellular effects of cells using pulsed electric fields
WO2015179666A1 (en) 2014-05-22 2015-11-26 Aegea Medical Inc. Systems and methods for performing endometrial ablation
US10179019B2 (en) 2014-05-22 2019-01-15 Aegea Medical Inc. Integrity testing method and apparatus for delivering vapor to the uterus
US10390838B1 (en) 2014-08-20 2019-08-27 Pneumrx, Inc. Tuned strength chronic obstructive pulmonary disease treatment
US10485604B2 (en) 2014-12-02 2019-11-26 Uptake Medical Technology Inc. Vapor treatment of lung nodules and tumors
WO2016100325A1 (en) 2014-12-15 2016-06-23 Virginia Tech Intellectual Properties, Inc. Devices, systems, and methods for real-time monitoring of electrophysical effects during tissue treatment
US10531906B2 (en) 2015-02-02 2020-01-14 Uptake Medical Technology Inc. Medical vapor generator
GB2550099B (en) 2015-03-24 2020-09-02 Gyrus Acmi Inc Airway stent
BR102015011376B1 (en) 2015-05-18 2023-04-04 Murilo Pundek Rocha IMPLANTABLE ARTIFICIAL BRONCHI
CN114983553A (en) 2016-02-19 2022-09-02 埃杰亚医疗公司 Method and apparatus for determining the integrity of a body cavity
US11331140B2 (en) 2016-05-19 2022-05-17 Aqua Heart, Inc. Heated vapor ablation systems and methods for treating cardiac conditions
US10448886B2 (en) 2016-08-17 2019-10-22 Covidien Lp Induced atelectasis and pulmonary consolidation systems and methods
US10905492B2 (en) 2016-11-17 2021-02-02 Angiodynamics, Inc. Techniques for irreversible electroporation using a single-pole tine-style internal device communicating with an external surface electrode
US11129673B2 (en) 2017-05-05 2021-09-28 Uptake Medical Technology Inc. Extra-airway vapor ablation for treating airway constriction in patients with asthma and COPD
US11344364B2 (en) 2017-09-07 2022-05-31 Uptake Medical Technology Inc. Screening method for a target nerve to ablate for the treatment of inflammatory lung disease
US11350988B2 (en) 2017-09-11 2022-06-07 Uptake Medical Technology Inc. Bronchoscopic multimodality lung tumor treatment
USD845467S1 (en) 2017-09-17 2019-04-09 Uptake Medical Technology Inc. Hand-piece for medical ablation catheter
US11419658B2 (en) 2017-11-06 2022-08-23 Uptake Medical Technology Inc. Method for treating emphysema with condensable thermal vapor
US11607537B2 (en) 2017-12-05 2023-03-21 Virginia Tech Intellectual Properties, Inc. Method for treating neurological disorders, including tumors, with electroporation
US11490946B2 (en) 2017-12-13 2022-11-08 Uptake Medical Technology Inc. Vapor ablation handpiece
US11925405B2 (en) 2018-03-13 2024-03-12 Virginia Tech Intellectual Properties, Inc. Treatment planning system for immunotherapy enhancement via non-thermal ablation
US11311329B2 (en) 2018-03-13 2022-04-26 Virginia Tech Intellectual Properties, Inc. Treatment planning for immunotherapy based treatments using non-thermal ablation techniques
WO2019232432A1 (en) 2018-06-01 2019-12-05 Santa Anna Tech Llc Multi-stage vapor-based ablation treatment methods and vapor generation and delivery systems
US11653927B2 (en) 2019-02-18 2023-05-23 Uptake Medical Technology Inc. Vapor ablation treatment of obstructive lung disease
USD902407S1 (en) 2019-11-19 2020-11-17 Pulmair Medical, Inc. Implantable artificial bronchus
USD954953S1 (en) 2020-11-03 2022-06-14 Pulmair Medical, Inc. Implantable artificial bronchus
USD1014758S1 (en) 2023-04-19 2024-02-13 Pulmair Medical, Inc. Implantable artificial bronchus

Citations (501)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2115298A (en) 1937-04-16 1938-04-26 Roderick F Brown Suction tonsillectome
US2479805A (en) 1946-08-15 1949-08-23 Toledo Engineering Company Inc Method of and apparatus for feeding batch materials
US2728225A (en) 1953-03-12 1955-12-27 Herbert E Skibitzke Thermal flowmeter
US2832078A (en) 1956-10-17 1958-04-29 Battelle Memorial Institute Heart valve
US2981254A (en) 1957-11-12 1961-04-25 Edwin G Vanderbilt Apparatus for the gas deflation of an animal's stomach
US3320972A (en) 1964-04-16 1967-05-23 Roy F High Prosthetic tricuspid valve and method of and device for fabricating same
US3370305A (en) 1965-05-28 1968-02-27 Goott Bernard Heart valve with magnetic hinge means
US3445916A (en) 1967-04-19 1969-05-27 Rudolf R Schulte Method for making an anatomical check valve
US3472230A (en) 1966-12-19 1969-10-14 Fogarty T J Umbrella catheter
US3540431A (en) 1968-04-04 1970-11-17 Kazi Mobin Uddin Collapsible filter for fluid flowing in closed passageway
US3617060A (en) 1967-04-10 1971-11-02 Warren Iezzi Pneumothorox-inducing hunting arrow
US3657744A (en) 1970-05-08 1972-04-25 Univ Minnesota Method for fixing prosthetic implants in a living body
US3671979A (en) 1969-09-23 1972-06-27 Univ Utah Catheter mounted artificial heart valve for implanting in close proximity to a defective natural heart valve
US3683913A (en) 1970-10-05 1972-08-15 Deknatel Inc Underwater drainage apparatus with air flow meters
US3757783A (en) 1971-09-24 1973-09-11 Sherwood Medical Ind Inc Suction drainage apparatus
US3760808A (en) 1969-12-01 1973-09-25 K Bleuer Tampon applicator assembly
US3788327A (en) 1971-03-30 1974-01-29 H Donowitz Surgical implant device
US3874388A (en) 1973-02-12 1975-04-01 Ochsner Med Found Alton Shunt defect closure system
US3889657A (en) 1974-02-12 1975-06-17 Gomco Surgical Mfg Co Uterine aspirating curette
US3962917A (en) 1974-07-03 1976-06-15 Minato Medical Science Co., Ltd. Respirometer having thermosensitive elements on both sides of a hot wire
US4014318A (en) 1973-08-20 1977-03-29 Dockum James M Circulatory assist device and system
US4040428A (en) 1976-08-30 1977-08-09 The Aro Corporation Control valves for tracheotomy patient or laryngeal prosthesis
US4056854A (en) 1976-09-28 1977-11-08 The United States Of America As Represented By The Department Of Health, Education And Welfare Aortic heart valve catheter
US4084268A (en) 1976-04-22 1978-04-18 Shiley Laboratories, Incorporated Prosthetic tissue heart valve
US4086665A (en) 1976-12-16 1978-05-02 Thermo Electron Corporation Artificial blood conduit
US4205282A (en) 1978-08-21 1980-05-27 Westinghouse Electric Corp. Phase shifting circuit element
US4212463A (en) 1978-02-17 1980-07-15 Pratt Enoch B Humane bleeder arrow
US4218782A (en) 1977-05-25 1980-08-26 Biocoating Anpartsselskab Heart valve prosthesis and method for the production thereof
US4222126A (en) 1978-12-14 1980-09-16 The United States Of America As Represented By The Secretary Of The Department Of Health, Education & Welfare Unitized three leaflet heart valve
US4250873A (en) 1977-04-26 1981-02-17 Richard Wolf Gmbh Endoscopes
US4267839A (en) 1979-09-12 1981-05-19 Repromed, Inc. Surgical instrument for use in reversible sterilization or permanent occlusion procedures
SU852321A1 (en) 1979-10-02 1981-08-07 Второй Московский Ордена Ленинагосударственный Медицинский Ин-Ститут Им. H.И.Пирогова Method of treating acute purulent diseases of lungs and pleura of children
US4301810A (en) 1980-02-29 1981-11-24 City Of Hope National Medical Center Ventilatory muscle training apparatus
US4302854A (en) 1980-06-04 1981-12-01 Runge Thomas M Electrically activated ferromagnetic/diamagnetic vascular shunt for left ventricular assist
US4339831A (en) 1981-03-27 1982-07-20 Medtronic, Inc. Dynamic annulus heart valve and reconstruction ring
USRE31040E (en) 1975-04-24 1982-09-28 St. Jude Medical, Inc. Heart valve prosthesis
US4393879A (en) 1980-04-11 1983-07-19 Milex Products, Inc. Tissue-collecting apparatus
US4402445A (en) 1981-10-09 1983-09-06 United States Surgical Corporation Surgical fastener and means for applying same
US4403616A (en) 1981-06-09 1983-09-13 K-Med, Inc. Expiratory breathing exercise device
JPS58163332U (en) 1982-04-27 1983-10-31 株式会社豊田自動織機製作所 Rear confirmation mirror device for forklift
US4456016A (en) 1982-07-01 1984-06-26 Trutek Research, Inc. Inhalation valve
GB2082071B (en) 1980-06-06 1984-07-11 Elliott Donald Paul Chest drainage
US4483200A (en) 1981-01-19 1984-11-20 Anima Corporation Thermal pulse flowmeter
JPS6010740Y2 (en) 1976-08-12 1985-04-11 アイダエンジニアリング株式会社 rotary clamper
US4512338A (en) 1983-01-25 1985-04-23 Balko Alexander B Process for restoring patency to body vessels
US4533137A (en) 1982-01-19 1985-08-06 Healthscan Inc. Pulmonary training method
US4569674A (en) 1982-08-03 1986-02-11 Stryker Corporation Continuous vacuum wound drainage system
US4582058A (en) 1984-11-26 1986-04-15 Bivona, Inc. Tracheostoma valves
US4583541A (en) 1984-05-07 1986-04-22 Barry Joseph P Sternal stabilization device
US4592741A (en) 1982-12-29 1986-06-03 Vincent Michel J Medical apparatus designed for the aspiration of phneumothorax
US4601465A (en) 1984-03-22 1986-07-22 Roy Jean Yves Device for stimulating the human respiratory system
US4610256A (en) 1984-09-25 1986-09-09 Utah Medical Products, Inc. Pressure transducer
US4619246A (en) 1984-05-23 1986-10-28 William Cook, Europe A/S Collapsible filter basket
US4654029A (en) 1982-12-13 1987-03-31 Howmedica, Inc. Electronic drainage system
US4654027A (en) 1985-10-30 1987-03-31 Dragan William B Vascular dilating device
US4681110A (en) 1985-12-02 1987-07-21 Wiktor Dominik M Catheter arrangement having a blood vessel liner, and method of using it
US4684363A (en) 1984-10-31 1987-08-04 American Hospital Supply Corporation Rapidly inflatable balloon catheter and method
US4685908A (en) 1984-10-18 1987-08-11 Bioresearch Ithaca Inc. Device for detecting increased pressure in pleural cavity
US4710192A (en) 1985-12-30 1987-12-01 Liotta Domingo S Diaphragm and method for occlusion of the descending thoracic aorta
SU1371700A1 (en) 1986-02-21 1988-02-07 МВТУ им.Н.Э.Баумана Prosthesis of heart valve
US4727873A (en) 1984-04-17 1988-03-01 Mobin Uddin Kazi Embolus trap
US4732152A (en) 1984-12-05 1988-03-22 Medinvent S.A. Device for implantation and a method of implantation in a vessel using such device
US4745925A (en) 1986-10-06 1988-05-24 Dietz Henry G Optoelectronic inhalation sensor for monitoring inhalation and for inhalation therapy
US4759758A (en) 1984-12-07 1988-07-26 Shlomo Gabbay Prosthetic heart valve
WO1988009683A1 (en) 1987-06-10 1988-12-15 Kletschka Harold D An angioplasty device
US4795449A (en) 1986-08-04 1989-01-03 Hollister Incorporated Female urinary incontinence device
US4799311A (en) 1987-02-26 1989-01-24 Matsutani Seisakusho Co., Ltd. Apparatus for attaching suture to surgical needle
US4808183A (en) 1980-06-03 1989-02-28 University Of Iowa Research Foundation Voice button prosthesis and method for installing same
US4819664A (en) 1984-11-15 1989-04-11 Stefano Nazari Device for selective bronchial intubation and separate lung ventilation, particularly during anesthesia, intensive therapy and reanimation
US4822354A (en) 1986-09-02 1989-04-18 Elosegui Ignacio M Mechanical valvular prothesis for use in cardiac surgery
US4830003A (en) 1988-06-17 1989-05-16 Wolff Rodney G Compressive stent and delivery system
US4832680A (en) 1986-07-03 1989-05-23 C.R. Bard, Inc. Apparatus for hypodermically implanting a genitourinary prosthesis
US4846836A (en) 1988-10-03 1989-07-11 Reich Jonathan D Artificial lower gastrointestinal valve
US4850999A (en) 1980-05-24 1989-07-25 Institute Fur Textil-Und Faserforschung Of Stuttgart Flexible hollow organ
US4852568A (en) 1987-02-17 1989-08-01 Kensey Nash Corporation Method and apparatus for sealing an opening in tissue of a living being
US4852552A (en) 1987-09-03 1989-08-01 Pilling Co. Sternal retractor
US4870975A (en) 1988-07-05 1989-10-03 Scott Cronk Suction canister assembly for the collection of body fluids and tissue specimens
US4877025A (en) 1988-10-06 1989-10-31 Hanson Donald W Tracheostomy tube valve apparatus
US4881939A (en) 1985-02-19 1989-11-21 The Johns Hopkins University Implantable helical cuff
US4888015A (en) 1982-08-20 1989-12-19 Domino Rudolph S Method of replacing an eye lens
US4896668A (en) 1986-04-10 1990-01-30 Peters Plate set for osteal fixation, equipped with suture strands
US4908028A (en) 1987-03-20 1990-03-13 Jean Colon Valve incorporating at least one rocking flap with respect to elastic pivots
WO1990003152A1 (en) 1988-09-24 1990-04-05 John Considine Electro-surgical apparatus for removing tumours from hollow organs of the body
US4920978A (en) 1988-08-31 1990-05-01 Triangle Research And Development Corporation Method and apparatus for the endoscopic treatment of deep tumors using RF hyperthermia
US4934999A (en) 1987-07-28 1990-06-19 Paul Bader Closure for a male urethra
US4936823A (en) 1988-05-04 1990-06-26 Triangle Research And Development Corp. Transendoscopic implant capsule
SU1593651A1 (en) 1987-07-07 1990-09-23 1-Й Московский Медицинский Институт Им.И.М.Сеченова Artery prosthesis
US4968294A (en) 1989-02-09 1990-11-06 Salama Fouad A Urinary control valve and method of using same
US4973047A (en) 1988-12-09 1990-11-27 Erik Norell Therapeutic device for lung exercise
US4979505A (en) 1989-06-06 1990-12-25 Cox Everard F Tracheal tube
US4984581A (en) 1988-10-12 1991-01-15 Flexmedics Corporation Flexible guide having two-way shape memory alloy
US4995872A (en) 1989-10-04 1991-02-26 Ferrara Janice J Expandable catheter and bridge device
US5002772A (en) 1988-05-31 1991-03-26 Pfizer Inc. Gastric retention system for controlled drug release
US5019086A (en) 1989-09-12 1991-05-28 Neward Theodore C Manipulable vacuum extractor for childbirth and method of using the same
US5033312A (en) 1989-11-06 1991-07-23 Bicore Monitoring Systems Gas flow meter housing
US5038621A (en) 1989-11-06 1991-08-13 Bicore Monitoring Systems Variable area obstruction gas flow meter
US5059208A (en) 1991-02-04 1991-10-22 Helix Medical, Inc. Adjustable tracheostoma valve
US5061274A (en) 1989-12-04 1991-10-29 Kensey Nash Corporation Plug device for sealing openings and method of use
US5078739A (en) 1990-07-20 1992-01-07 Janus Biomedical, Inc. Bileaflet heart valve with external leaflets
US5092781A (en) 1990-11-08 1992-03-03 Amp Incorporated Electrical connector using shape memory alloy coil springs
US5111823A (en) 1989-04-20 1992-05-12 National Fertility Institute Apparatus and method for generating echographic images
US5116360A (en) 1990-12-27 1992-05-26 Corvita Corporation Mesh composite graft
US5116564A (en) 1988-10-11 1992-05-26 Josef Jansen Method of producing a closing member having flexible closing elements, especially a heart valve
US5123919A (en) 1991-11-21 1992-06-23 Carbomedics, Inc. Combined prosthetic aortic heart valve and vascular graft
WO1992010725A1 (en) 1990-12-11 1992-06-25 Abbey Biosystems Limited Hot wire anemometer
US5127412A (en) 1990-03-14 1992-07-07 Cosmetto Aristodeme J Skin tensioning
US5135488A (en) 1989-03-17 1992-08-04 Merit Medical Systems, Inc. System and method for monitoring, displaying and recording balloon catheter inflation data
US5135531A (en) 1984-05-14 1992-08-04 Surgical Systems & Instruments, Inc. Guided atherectomy system
US5147369A (en) 1991-07-01 1992-09-15 Wagner Michael A Forceps and method for nuclear fragment removal
US5151105A (en) 1991-10-07 1992-09-29 Kwan Gett Clifford Collapsible vessel sleeve implant
US5158548A (en) 1990-04-25 1992-10-27 Advanced Cardiovascular Systems, Inc. Method and system for stent delivery
US5161524A (en) 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
US5171299A (en) 1991-08-02 1992-12-15 Baxter International Inc. Balloon catheter inflation pressure and diameter display apparatus and method
US5186711A (en) 1989-03-07 1993-02-16 Albert Einstein College Of Medicine Of Yeshiva University Hemostasis apparatus and method
US5197963A (en) 1991-12-02 1993-03-30 Everest Medical Corporation Electrosurgical instrument with extendable sheath for irrigation and aspiration
US5197485A (en) 1991-10-15 1993-03-30 Pilling Co. Method and apparatus for sampling aortic plaque
US5197980A (en) 1990-08-14 1993-03-30 Gorshkov Jury V Cardiac valve prosthesis
US5207702A (en) 1991-08-14 1993-05-04 Pearl Michael L Method and apparatus for handling hygroscopic dilators
US5226429A (en) 1991-06-20 1993-07-13 Inamed Development Co. Laparoscopic gastric band and method
US5255687A (en) 1992-01-21 1993-10-26 Mckenna Charles L Zero dead space respiratory exercise valve
US5275169A (en) 1992-01-15 1994-01-04 Innovation Associates Apparatus and method for determining physiologic characteristics of body lumens
US5281229A (en) 1991-08-09 1994-01-25 Neward Theodore C Obstetrical vacuum extractor
US5283063A (en) 1992-01-31 1994-02-01 Eagle Vision Punctum plug method and apparatus
US5300050A (en) 1986-10-07 1994-04-05 Deknatel Technology Corporation Drainage device
US5304199A (en) 1993-01-04 1994-04-19 Gene E. Myers Enterprises, Inc. Apparatus for arterial total occlusion plaque separation
US5306234A (en) 1993-03-23 1994-04-26 Johnson W Dudley Method for closing an atrial appendage
US5314473A (en) 1989-07-20 1994-05-24 Godin Norman J Prosthesis for preventing gastric reflux into the esophagus
US5339805A (en) 1989-11-08 1994-08-23 Parker Jeffrey D Blind orolaryngeal and oroesophageal guiding and aiming device
US5342298A (en) 1992-07-31 1994-08-30 Advanced Cardiovascular Systems, Inc. Automated fluid pressure control system
US5352240A (en) 1989-05-31 1994-10-04 Promedica International, Inc. Human heart valve replacement with porcine pulmonary valve
US5353470A (en) 1991-04-18 1994-10-11 Ryobi Motor Products Corporation Horizontal canister vacuum
US5356412A (en) 1992-10-09 1994-10-18 United States Surgical Corporation Sternum buckle with rotational engagement and method of closure
US5358518A (en) 1991-06-25 1994-10-25 Sante Camilli Artificial venous valve
US5366478A (en) 1993-07-27 1994-11-22 Ethicon, Inc. Endoscopic surgical sealing device
US5366475A (en) 1992-12-21 1994-11-22 Shatzu Health Products, Inc. Tragus acupressure clip
WO1994026175A1 (en) 1993-05-06 1994-11-24 Vitaphore Corporation Embolization device
US5370657A (en) 1993-03-26 1994-12-06 Scimed Life Systems, Inc. Recoverable thrombosis filter
US5382261A (en) 1992-09-01 1995-01-17 Expandable Grafts Partnership Method and apparatus for occluding vessels
US5383470A (en) 1993-09-20 1995-01-24 Steve Novak Portable spirometer
US5391205A (en) 1991-12-17 1995-02-21 Knight; Roy F. Tracheoesophageal voice prosthesis
US5392775A (en) 1994-03-22 1995-02-28 Adkins, Jr.; Claude N. Duckbill valve for a tracheostomy tube that permits speech
US5398844A (en) 1994-01-31 1995-03-21 Boston Scientific Corporation Multiple ligating band dispenser
US5409444A (en) 1992-03-04 1995-04-25 Kensey Nash Corporation Method and apparatus to reduce injury to the vascular system
US5409019A (en) 1992-10-30 1995-04-25 Wilk; Peter J. Coronary artery by-pass method
US5411507A (en) 1993-01-08 1995-05-02 Richard Wolf Gmbh Instrument for implanting and extracting stents
US5411552A (en) 1990-05-18 1995-05-02 Andersen; Henning R. Valve prothesis for implantation in the body and a catheter for implanting such valve prothesis
US5413599A (en) 1988-09-20 1995-05-09 Nippon Zeon Co., Ltd. Medical valve apparatus
US5415658A (en) 1993-12-14 1995-05-16 Pioneer Laboratories, Inc. Surgical cable loop connector
US5415660A (en) 1994-01-07 1995-05-16 Regents Of The University Of Minnesota Implantable limb lengthening nail driven by a shape memory alloy
US5417226A (en) 1994-06-09 1995-05-23 Juma; Saad Female anti-incontinence device
US5421325A (en) 1992-04-30 1995-06-06 Cinberg; James Z. Endotracheal tube assembly and related method
US5423830A (en) 1993-07-07 1995-06-13 Schneebaum; Cary W. Polyp retrieval method and associated instrument assembly
US5445626A (en) 1991-12-05 1995-08-29 Gigante; Luigi Valve operated catheter for urinary incontinence and retention
US5453090A (en) 1994-03-01 1995-09-26 Cordis Corporation Method of stent delivery through an elongate softenable sheath
US5456689A (en) 1993-10-13 1995-10-10 Arnold J. Kresch Method and device for tissue resection
US5459544A (en) 1993-02-01 1995-10-17 Konica Corporation Camera with a shape memory alloy member
WO1995032018A1 (en) 1994-05-25 1995-11-30 Teirstein Paul S Body passageway closure apparatus and method
US5484444A (en) 1992-10-31 1996-01-16 Schneider (Europe) A.G. Device for the implantation of self-expanding endoprostheses
US5486154A (en) 1993-06-08 1996-01-23 Kelleher; Brian S. Endoscope
US5490860A (en) 1993-12-08 1996-02-13 Sofamor Danek Properties, Inc. Portable power cutting tool
WO1996004875A1 (en) 1994-08-08 1996-02-22 Inbae Yoon Multifunctional devices having loop configured portions and collection systems for endoscopic surgical procedures and methods therefor
JPH0819544B2 (en) 1993-02-05 1996-02-28 協和電線株式会社 Lead steel wire for electronic parts and manufacturing method thereof
US5500014A (en) 1989-05-31 1996-03-19 Baxter International Inc. Biological valvular prothesis
US5503638A (en) 1994-02-10 1996-04-02 Bio-Vascular, Inc. Soft tissue stapling buttress
US5507754A (en) 1993-08-20 1996-04-16 United States Surgical Corporation Apparatus and method for applying and adjusting an anchoring device
US5507797A (en) 1993-08-20 1996-04-16 Sumitomo Bakelite Company Limited Slidable kit for endoscopic ligation
US5509900A (en) 1992-03-02 1996-04-23 Kirkman; Thomas R. Apparatus and method for retaining a catheter in a blood vessel in a fixed position
USRE35225E (en) 1987-03-02 1996-04-30 Atrium Medical Corporation Fluid recovery system
US5514153A (en) 1990-03-02 1996-05-07 General Surgical Innovations, Inc. Method of dissecting tissue layers
US5549626A (en) 1994-12-23 1996-08-27 New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Vena caval filter
US5562641A (en) 1993-05-28 1996-10-08 A Bromberg & Co. Ltd. Two way shape memory alloy medical stent
US5562728A (en) 1983-12-09 1996-10-08 Endovascular Tech Inc Endovascular grafting apparatus, system and method and devices for use therewith
US5562608A (en) 1989-08-28 1996-10-08 Biopulmonics, Inc. Apparatus for pulmonary delivery of drugs with simultaneous liquid lavage and ventilation
WO1996034582A1 (en) 1995-05-05 1996-11-07 Angiomed Gmbh & Co. Medizintechnik Kg Endosphincter, set for releasably closing the urethra and process for inserting an endosphincter into the urethra
US5575293A (en) 1995-02-06 1996-11-19 Promex, Inc. Apparatus for collecting and staging tissue
WO1996037167A1 (en) 1995-05-25 1996-11-28 Raychem Corporation Stent assembly
US5593413A (en) 1990-05-14 1997-01-14 Medisys Technologies, Inc. Device for assisting childbirth
US5603698A (en) 1993-04-13 1997-02-18 Boston Scientific Corporation Prosthesis delivery system
US5607469A (en) 1993-10-28 1997-03-04 Inocor Gmbh Bi-leaflet prosthetic heart valve
WO1997009932A1 (en) 1995-09-12 1997-03-20 Boston Scientific Corporation Stent delivery system
WO1997013471A1 (en) 1995-10-13 1997-04-17 Transvascular, Inc. A device, system and method for interstitial transvascular intervention
EP0743071A3 (en) 1995-04-24 1997-04-23 Haemonetics Corp Autotransfusion apparatus
US5645565A (en) 1995-06-13 1997-07-08 Ethicon Endo-Surgery, Inc. Surgical plug
US5647857A (en) 1995-03-16 1997-07-15 Endotex Interventional Systems, Inc. Protective intraluminal sheath
US5649953A (en) 1992-09-28 1997-07-22 Bentex Trading S.A. Kit for medical use composed of a filter and a device for placing it in the vessel
WO1997027893A1 (en) 1996-02-02 1997-08-07 Transvascular, Inc. Methods and apparatus for blocking flow through blood vessels
US5660175A (en) 1995-08-21 1997-08-26 Dayal; Bimal Endotracheal device
US5662622A (en) 1995-04-04 1997-09-02 Cordis Corporation Intravascular catheter
US5662713A (en) 1991-10-09 1997-09-02 Boston Scientific Corporation Medical stents for body lumens exhibiting peristaltic motion
US5669933A (en) 1996-07-17 1997-09-23 Nitinol Medical Technologies, Inc. Removable embolus blood clot filter
US5676671A (en) 1995-04-12 1997-10-14 Inoue; Kanji Device for introducing an appliance to be implanted into a catheter
US5683451A (en) 1994-06-08 1997-11-04 Cardiovascular Concepts, Inc. Apparatus and methods for deployment release of intraluminal prostheses
WO1997042871A1 (en) 1996-05-10 1997-11-20 Cardiovascular Concepts, Inc. Lesion diameter measurement catheter and method
US5690644A (en) 1992-12-30 1997-11-25 Schneider (Usa) Inc. Apparatus for deploying body implantable stent
US5697968A (en) 1995-08-10 1997-12-16 Aeroquip Corporation Check valve for intraluminal graft
US5702343A (en) 1996-10-02 1997-12-30 Acorn Medical, Inc. Cardiac reinforcement device
US5702409A (en) 1995-07-21 1997-12-30 W. L. Gore & Associates, Inc. Device and method for reinforcing surgical staples
WO1998000840A1 (en) 1996-06-28 1998-01-08 Samsung Electronics Co., Ltd. Thin film magnetic head tip and manufacturing method therefor
WO1998001084A1 (en) 1996-07-04 1998-01-15 Carlo Rebuffat Surgical appliance for the treatment of pulmonary emphysema
WO1998008441A1 (en) 1996-08-29 1998-03-05 Ethicon Endo-Surgery Methods and devices for collection of soft tissue
US5725519A (en) 1996-09-30 1998-03-10 Medtronic Instent Israel Ltd. Stent loading device for a balloon catheter
US5741271A (en) 1991-11-05 1998-04-21 Nakao; Naomi L. Surgical retrieval assembly and associated method
WO1998019633A1 (en) 1996-11-06 1998-05-14 Percusurge, Inc. Apparatus and method for loading a stent on a catheter
US5752522A (en) 1995-05-04 1998-05-19 Cardiovascular Concepts, Inc. Lesion diameter measurement catheter and method
US5752965A (en) 1996-10-21 1998-05-19 Bio-Vascular, Inc. Apparatus and method for producing a reinforced surgical fastener suture line
US5755770A (en) 1995-01-31 1998-05-26 Boston Scientific Corporatiion Endovascular aortic graft
US5763979A (en) 1996-02-29 1998-06-09 The United States Of America As Represented By The Secretary Of The Navy Actuation system for the control of multiple shape memory alloy elements
US5766134A (en) 1995-07-18 1998-06-16 Atrion Medical Products, Inc. Autogenous bone specimen collector
US5769892A (en) 1996-10-22 1998-06-23 Mitroflow International Inc. Surgical stapler sleeve for reinforcing staple lines
US5772583A (en) 1994-01-21 1998-06-30 Wright; John T. M. Sternal retractor with attachments for mitral & tricuspid valve repair
US5779649A (en) 1996-12-17 1998-07-14 Pabban Development, Inc. Surgical suction wand with filter
US5782896A (en) 1997-01-29 1998-07-21 Light Sciences Limited Partnership Use of a shape memory alloy to modify the disposition of a device within an implantable medical probe
US5797960A (en) 1993-02-22 1998-08-25 Stevens; John H. Method and apparatus for thoracoscopic intracardiac procedures
US5797920A (en) 1996-06-14 1998-08-25 Beth Israel Deaconess Medical Center Catheter apparatus and method using a shape-memory alloy cuff for creating a bypass graft in-vivo
US5797907A (en) 1989-11-06 1998-08-25 Mectra Labs, Inc. Electrocautery cutter
US5800339A (en) 1989-02-09 1998-09-01 Opticon Medical Inc. Urinary control valve
US5803078A (en) 1994-05-06 1998-09-08 Brauner; Mark E. Methods and apparatus for intrapulmonary therapy and drug administration
WO1998039047A1 (en) 1997-03-06 1998-09-11 Percusurge, Inc. Aspiration system and method
WO1997044085A3 (en) 1996-05-20 1998-09-17 Percusurge Inc Low profile catheter valve
US5810809A (en) 1997-01-13 1998-09-22 Enhanced Orthopaedic Technologies, Inc. Arthroscopic shaver incorporating electrocautery
US5810855A (en) 1995-07-21 1998-09-22 Gore Enterprise Holdings, Inc. Endoscopic device and method for reinforcing surgical staples
US5810837A (en) 1992-12-16 1998-09-22 Schneider (Europe) A.G. Device for the implantation of a self-expanding endoprosthesis
US5817101A (en) 1997-03-13 1998-10-06 Schneider (Usa) Inc Fluid actuated stent delivery system
US5830217A (en) 1996-08-09 1998-11-03 Thomas J. Fogarty Soluble fixation device and method for stent delivery catheters
GB2324729A (en) 1997-04-30 1998-11-04 Bradford Hospitals Nhs Trust Lung treatment device
WO1998044854B1 (en) 1998-02-27 1998-11-19 Bronchial stenter
US5840081A (en) 1990-05-18 1998-11-24 Andersen; Henning Rud System and method for implanting cardiac valves
US5851232A (en) 1997-03-15 1998-12-22 Lois; William A. Venous stent
US5855587A (en) 1996-06-13 1999-01-05 Chon-Ik Hyon Hole forming device for pierced earrings
US5855597A (en) 1997-05-07 1999-01-05 Iowa-India Investments Co. Limited Stent valve and stent graft for percutaneous surgery
US5855601A (en) 1996-06-21 1999-01-05 The Trustees Of Columbia University In The City Of New York Artificial heart valve and method and device for implanting the same
WO1999001076A1 (en) 1997-07-02 1999-01-14 Broncus Technologies, Inc. Bleb reducer
US5865724A (en) 1996-01-11 1999-02-02 Symbiosis Corp. Flexible microsurgical instruments incorporating a sheath having tactile and visual position indicators
US5876434A (en) 1997-07-13 1999-03-02 Litana Ltd. Implantable medical devices of shape memory alloy
US5876445A (en) 1991-10-09 1999-03-02 Boston Scientific Corporation Medical stents for body lumens exhibiting peristaltic motion
WO1999013801A1 (en) 1997-09-16 1999-03-25 Zadno Azizi Gholam Reza Body fluid flow control device
US5895387A (en) 1996-10-09 1999-04-20 Romulo Guerrero Method of craniofacial bone distraction
US5902312A (en) 1995-07-03 1999-05-11 Frater; Dirk A. System for mounting bolster material on tissue staplers
WO1999026692A1 (en) 1997-11-20 1999-06-03 Percusurge, Inc. Low profile catheter valve and inflation adaptor
US5911756A (en) 1996-06-26 1999-06-15 Novatech Intralaryngeal prosthesis
WO1999032040A1 (en) 1997-12-19 1999-07-01 Broncus Technologies, Inc. Bronchial stenter
US5925063A (en) 1997-09-26 1999-07-20 Khosravi; Farhad Coiled sheet valve, filter or occlusive device and methods of use
US5944738A (en) 1998-02-06 1999-08-31 Aga Medical Corporation Percutaneous catheter directed constricting occlusion device
US5947997A (en) 1992-11-25 1999-09-07 William Cook Europe A/S Closure prothesis for transcatheter placement
US5954636A (en) 1997-07-15 1999-09-21 Schwartz; Roy E. Pediatric endotracheal tube with bronchial blocker and method for selectively blocking respiratory airflow to a pediatric patient's lung
US5957949A (en) 1997-05-01 1999-09-28 World Medical Manufacturing Corp. Percutaneous placement valve stent
US5957978A (en) 1997-12-22 1999-09-28 Hansa Medical Products, Inc. Valved fenestrated tracheotomy tube
US5972009A (en) 1998-04-07 1999-10-26 Boston Scientific Corporation Ligating band with rounded edges and method of use of same
RU2140211C1 (en) 1998-10-28 1999-10-27 Российская медицинская академия последипломного образования Министерства здравоохранения Российской Федерации Method of surgical treatment of patients with pathology of respiratory organs complicated with pulmonary hemorrhages
WO1999042161A3 (en) 1998-02-19 1999-10-28 Percusurge Inc Low profile fluid delivery and sealing system for a catheter
US5976174A (en) 1997-12-15 1999-11-02 Ruiz; Carlos E. Medical hole closure device and methods of use
US5976158A (en) 1997-06-02 1999-11-02 Boston Scientific Corporation Method of using a textured ligating band
US5980545A (en) 1996-05-13 1999-11-09 United States Surgical Corporation Coring device and method
WO1999042059A3 (en) 1998-02-19 1999-11-11 Percusurge Inc Occlusion of a vessel
US5984965A (en) 1997-08-28 1999-11-16 Urosurge, Inc. Anti-reflux reinforced stent
US5989234A (en) 1997-01-14 1999-11-23 Deknatel Technology Corporation Device and system for draining a body cavity and methods related thereto
WO1999064109A1 (en) 1998-06-10 1999-12-16 Broncus Technologies, Inc. Smooth muscle treatment apparatus and method
US6003517A (en) 1998-04-30 1999-12-21 Ethicon Endo-Surgery, Inc. Method for using an electrosurgical device on lung tissue
US6007575A (en) 1997-06-06 1999-12-28 Samuels; Shaun Laurence Wilkie Inflatable intraluminal stent and method for affixing same within the human body
US6010525A (en) 1997-08-01 2000-01-04 Peter M. Bonutti Method and apparatus for securing a suture
US6009614A (en) 1998-04-21 2000-01-04 Advanced Cardiovascular Systems, Inc. Stent crimping tool and method of use
WO1999059503A8 (en) 1998-05-15 2000-01-20 American Med Syst Method and device for loading a stent
US6020380A (en) 1998-11-25 2000-02-01 Tap Holdings Inc. Method of treating chronic obstructive pulmonary disease
US6024759A (en) 1998-05-08 2000-02-15 Walter Lorenz Surgical, Inc. Method and apparatus for performing pectus excavatum repair
US6027525A (en) 1996-05-23 2000-02-22 Samsung Electronics., Ltd. Flexible self-expandable stent and method for making the same
WO2000012011A1 (en) 1998-08-27 2000-03-09 Shoshan Hendler Apparatus and method for acquisition and retrieval of resected biological specimens
US6045560A (en) 1993-10-06 2000-04-04 United States Surgical Corporation Surgical stapling apparatus with biocompatible surgical fabric
WO2000018329A1 (en) 1998-09-30 2000-04-06 Impra, Inc. Apparatus for loading a bag enclosed stent on a catheter
FR2773702B1 (en) 1998-01-16 2000-04-07 Johnson & Johnson Internationa COMPRESSION DEVICE FOR HEMOSTASIS OF AN ORGAN, SUCH AS LIVER
US6051022A (en) 1998-12-30 2000-04-18 St. Jude Medical, Inc. Bileaflet valve having non-parallel pivot axes
US6053877A (en) 1994-02-08 2000-04-25 Boston Scientific Corporation Movable sample tube multiple biopsy sampling device
US6062575A (en) 1994-07-27 2000-05-16 Mednext, Inc. Tool shaft coupler
US6068635A (en) 1998-03-04 2000-05-30 Schneider (Usa) Inc Device for introducing an endoprosthesis into a catheter shaft
US6077214A (en) 1998-07-29 2000-06-20 Myocor, Inc. Stress reduction apparatus and method
US6077291A (en) 1992-01-21 2000-06-20 Regents Of The University Of Minnesota Septal defect closure device
US6079413A (en) 1994-06-17 2000-06-27 Trudell Medical Limited Catheter system for delivery of aerosolized medicine for use with pressurized propellant canister
US6083141A (en) 1995-02-10 2000-07-04 Hougen; Everett D. Portable respiratory exercise apparatus and method for using the same
US6086543A (en) 1998-06-24 2000-07-11 Rubicor Medical, Inc. Fine needle and core biopsy devices and methods
US6090041A (en) 1999-02-16 2000-07-18 Regents Of The University Of California vacuum actuated surgical retractor and methods
US6090035A (en) 1999-03-19 2000-07-18 Isostent, Inc. Stent loading assembly for a self-expanding stent
US6099551A (en) 1998-03-12 2000-08-08 Shelhigh, Inc. Pericardial strip and stapler assembly for dividing and sealing visceral tissues and method of use thereof
US6102926A (en) 1996-12-02 2000-08-15 Angiotrax, Inc. Apparatus for percutaneously performing myocardial revascularization having means for sensing tissue parameters and methods of use
US6102885A (en) 1996-08-08 2000-08-15 Bass; Lawrence S. Device for suction-assisted lipectomy and method of using same
WO2000051510A1 (en) 1999-03-01 2000-09-08 Broncus Technologies, Inc. Bronchial stenter having expandable electrodes
US6135729A (en) 1993-11-10 2000-10-24 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Blood pump bearing system
US6135991A (en) 1997-03-06 2000-10-24 Percusurge, Inc. Aspiration method
EP0665029B1 (en) 1994-01-27 2000-11-02 The Kendall Company Esophageal-tracheal double lumen airway
US6141855A (en) 1998-04-28 2000-11-07 Advanced Cardiovascular Systems, Inc. Stent crimping tool and method of use
US6142957A (en) 1993-09-20 2000-11-07 Boston Scientific Corporation Multiple biopsy sampling device
US6146357A (en) 1999-05-07 2000-11-14 Embol-X, Inc. Balloon occlusion diameter and pressure measuring devices and methods of use
US6146384A (en) 1995-10-13 2000-11-14 Sdgi Holdings, Inc. Orthopedic fixation device and method of implantation
US6146388A (en) 1999-06-21 2000-11-14 Surgical Concepts, Inc. Rocking apparatus for manipulating element in the eye
US6149664A (en) 1998-08-27 2000-11-21 Micrus Corporation Shape memory pusher introducer for vasoocclusive devices
WO2000042950A3 (en) 1999-01-26 2000-11-30 Edwards Lifesciences Corp Flexible heart valve
US6162245A (en) 1997-05-07 2000-12-19 Iowa-India Investments Company Limited Stent valve and stent graft
US6165179A (en) 1995-05-23 2000-12-26 Boston Scientific Corporation Vena cava delivery system
WO2000078407A1 (en) 1999-06-18 2000-12-28 Powerlung Inc Pulmonary exercise device
WO2000078386A1 (en) 1999-06-23 2000-12-28 Medtronic Percusurge, Inc. Integrated inflation/deflation device and method
US6168617B1 (en) 1999-06-14 2001-01-02 Scimed Life Systems, Inc. Stent delivery system
CA2375752A1 (en) 1999-07-02 2001-01-11 Pulmonx Methods, systems, and kits for lung volume reduction
US6174307B1 (en) 1996-03-29 2001-01-16 Eclipse Surgical Technologies, Inc. Viewing surgical scope for minimally invasive procedures
US6174323B1 (en) 1998-06-05 2001-01-16 Broncus Technologies, Inc. Method and assembly for lung volume reduction
WO2001003642A1 (en) 1999-07-08 2001-01-18 Broncus Technologies, Inc. Increasing gas exchange of a lung
WO2001003641A1 (en) 1999-07-07 2001-01-18 Astrazeneca Ab Closure device for a medical container
WO2001005334A1 (en) 1999-07-19 2001-01-25 Sulzer Carbomedics Inc. Heart valve leaflet with reinforced free margin
US6183520B1 (en) 1996-08-13 2001-02-06 Galt Laboratories, Inc. Method of maintaining urinary continence
WO2001010314A2 (en) 1999-08-05 2001-02-15 Broncus Technologies, Inc. Methods and devices for creating collateral channels in the lungs
WO2001010313A1 (en) 1999-08-05 2001-02-15 Kensey Nash Corporation System and method for delivering agents into targeted tissue of a living being
WO2001012104A1 (en) 1999-08-13 2001-02-22 Percusurge, Inc. Occlusion of a vessel
US6193748B1 (en) 1997-02-12 2001-02-27 Schneider (Usa) Inc Occlusion device
WO2001013839A1 (en) 1999-08-24 2001-03-01 Spiration, Inc. Lung reduction device, system, and method
WO2001015604A1 (en) 1999-08-31 2001-03-08 The University Of Western Australia Methods and devices for obtaining samples from hollow viscera
US6200333B1 (en) 1997-04-07 2001-03-13 Broncus Technologies, Inc. Bronchial stenter
US6203551B1 (en) 1999-10-04 2001-03-20 Advanced Cardiovascular Systems, Inc. Chamber for applying therapeutic substances to an implant device
US6206918B1 (en) 1999-05-12 2001-03-27 Sulzer Carbomedics Inc. Heart valve prosthesis having a pivot design for improving flow characteristics
US6210338B1 (en) 1998-08-21 2001-04-03 Aga Medical Corp. Sizing catheter for measuring cardiovascular structures
US6213957B1 (en) 1995-09-08 2001-04-10 United States Surgical Corporation Apparatus and method for removing tissue
WO2000062699A3 (en) 1999-04-21 2001-04-26 Broncus Tech Inc Modification of airways by application of energy
WO2001028433A1 (en) 1999-10-20 2001-04-26 Spiration, Inc. Apparatus and method for expanding the thorax
WO2001030268A1 (en) 1999-10-27 2001-05-03 Atritech, Inc. Barrier device for ostium of left atrial appendage
US6227083B1 (en) 1999-07-30 2001-05-08 Fa-Hsi Tseng Chamfer forming head for paper roll
US6231589B1 (en) 1999-03-22 2001-05-15 Microvena Corporation Body vessel filter
US20010001817A1 (en) 1995-06-05 2001-05-24 Humes H. David Implantable device and use therefor
US6238334B1 (en) 1997-11-03 2001-05-29 Cardio Technologies, Inc. Method and apparatus for assisting a heart to pump blood
US6241758B1 (en) 1999-05-28 2001-06-05 Advanced Cardiovascular Systems, Inc. Self-expanding stent delivery system and method of use
US6241678B1 (en) 1998-08-21 2001-06-05 Aga Medical Corporation Sizing catheter for measuring septal defects
US6241654B1 (en) 1999-07-07 2001-06-05 Acorn Cardiovasculr, Inc. Cardiac reinforcement devices and methods
US6240615B1 (en) 1998-05-05 2001-06-05 Advanced Cardiovascular Systems, Inc. Method and apparatus for uniformly crimping a stent onto a catheter
US6245102B1 (en) 1997-05-07 2001-06-12 Iowa-India Investments Company Ltd. Stent, stent graft and stent valve
US6264700B1 (en) 1998-08-27 2001-07-24 Endonetics, Inc. Prosthetic gastroesophageal valve
WO2001052775A1 (en) 2000-01-17 2001-07-26 Wittens Cornelis Hendrikus Ann Implant valve for implantation in a blood vessel
US20010010017A1 (en) 1996-12-31 2001-07-26 Brice Letac Alve prosthesis for implantation in body channels
US6267775B1 (en) 1997-03-21 2001-07-31 Schneider (Usa) Inc. Self-expanding medical device for centering radioactive treatment sources in body vessels
WO2001054625A1 (en) 2000-01-31 2001-08-02 Cook Biotech Incorporated Stent valves and uses of same
WO2001054685A1 (en) 2000-01-31 2001-08-02 Genaera Corporation Mucin synthesis inhibitors
US6270527B1 (en) 1998-10-16 2001-08-07 Sulzer Carbomedics Inc. Elastic valve with partially exposed stent
US20010012949A1 (en) 1998-03-13 2001-08-09 Forber Simon J. Covered self-expanding vascular occlusion device
US6280398B1 (en) 1999-10-18 2001-08-28 Ethicon Endo-Surgery Methods and devices for collection of soft tissue
US6287334B1 (en) 1996-12-18 2001-09-11 Venpro Corporation Device for regulating the flow of blood through the blood system
WO2001070114A1 (en) 2000-03-17 2001-09-27 Rita Medical Systems Inc. Lung treatment apparatus
US20010025132A1 (en) 2000-03-23 2001-09-27 Spiration, Inc. Tissue resection device, system and method
US6296639B1 (en) 1999-02-12 2001-10-02 Novacept Apparatuses and methods for interstitial tissue removal
US6299604B1 (en) 1998-08-20 2001-10-09 Cook Incorporated Coated implantable medical device
WO2001074271A1 (en) 2000-03-31 2001-10-11 Broncus Technologies, Inc. Lung elastic recoil restoring/compression device
US6302893B1 (en) 1996-07-15 2001-10-16 Advanced Cardiovascular Systems, Inc. Self-expanding stent delivery system
US20010034518A1 (en) 1994-06-24 2001-10-25 Curon Medical, Inc. Sphincter treatment apparatus
US20010037808A1 (en) 2000-03-04 2001-11-08 Deem Mark E. Methods and devices for use in performing pulmonary procedures
CA2408923A1 (en) 2000-05-18 2001-11-22 David Peter Shaw Bronchiopulmonary occlusion devices and lung volume reduction methods
US6322522B1 (en) 1997-09-22 2001-11-27 Zimmon Science Corp. Apparatus for separable external serial collection, storage and processing of biopsy specimens
WO2001089366A2 (en) 2000-05-23 2001-11-29 Broncus Technologies, Inc. Method and assembly for lung volume reduction
US6325777B1 (en) 1996-05-20 2001-12-04 Medtronic Percusurge, Inc. Low profile catheter valve and inflation adaptor
US6327505B1 (en) 1998-05-07 2001-12-04 Medtronic, Inc. Method and apparatus for rf intraluminal reduction and occlusion
US6327772B1 (en) 1996-01-30 2001-12-11 Medtronic, Inc. Method for fabricating a planar eversible lattice which forms a stent when everted
US20010051799A1 (en) 1999-08-23 2001-12-13 Ingenito Edward P. Tissue volume reduction
US6331183B1 (en) 1998-09-24 2001-12-18 Scimed Life Systems, Inc. Basket filter
US20010052344A1 (en) 2000-06-16 2001-12-20 Rajiv Doshi Methods and devices for improving breathing in patients with pulmonary disease
US20020002401A1 (en) 2000-06-26 2002-01-03 Mcguckin James F. Vascular device for valve leaflet apposition
US20020007831A1 (en) 2000-07-19 2002-01-24 Davenport Paul W. Method for treating chronic obstructive pulmonary disorder
WO2001049213A3 (en) 1999-12-31 2002-01-24 Advanced Bio Prosthetic Surfac Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof
US6342062B1 (en) 1998-09-24 2002-01-29 Scimed Life Systems, Inc. Retrieval devices for vena cava filter
US6350278B1 (en) 1994-06-08 2002-02-26 Medtronic Ave, Inc. Apparatus and methods for placement and repositioning of intraluminal prostheses
WO2001045590A3 (en) 1999-12-23 2002-03-07 Percusurge Inc Strut design for an occlusion device
US20020029004A1 (en) 1998-02-25 2002-03-07 Respironics, Inc. Patient monitor and method of using same
US20020038125A1 (en) 1999-12-07 2002-03-28 Peter Hamilton Flexible vacuum grabber for holding lesions
WO2002032333A1 (en) 2000-10-17 2002-04-25 Broncus Technologies, Inc. Control system and process for application of energy to airway walls and other mediums
US20020052626A1 (en) 1997-11-07 2002-05-02 Paul Gilson Embolic protection system
AU2002239759A1 (en) 2000-10-27 2002-05-21 Pulmonx Methods and devices for obstructing and aspirating lung tissue segments
US6398775B1 (en) 1999-10-21 2002-06-04 Pulmonx Apparatus and method for isolated lung access
US20020072730A1 (en) 2000-10-12 2002-06-13 Mcgill Scott A. Methods and apparatus for protecting the proximal end of a medical device
US20020077564A1 (en) 1996-07-29 2002-06-20 Farallon Medsystems, Inc. Thermography catheter
US20020087153A1 (en) 1999-08-05 2002-07-04 Broncus Technologies, Inc. Devices for creating collateral channels
US6416554B1 (en) 1999-08-24 2002-07-09 Spiration, Inc. Lung reduction apparatus and method
US20020091411A1 (en) 2000-12-07 2002-07-11 Saker Mark B. Tissue tract sealing device
US6425916B1 (en) 1999-02-10 2002-07-30 Michi E. Garrison Methods and devices for implanting cardiac valves
US6428561B1 (en) 1996-06-05 2002-08-06 Astra Aktiebolag Biocompatible glue
US20020111620A1 (en) 2001-02-14 2002-08-15 Broncus Technologies, Inc. Devices and methods for maintaining collateral channels in tissue
US20020111619A1 (en) 1999-08-05 2002-08-15 Broncus Technologies, Inc. Devices for creating collateral channels
WO2001030266A9 (en) 1999-10-27 2002-08-15 Atritech Inc Filter apparatus for ostium of left atrial appendage
US20020112729A1 (en) 2001-02-21 2002-08-22 Spiration, Inc. Intra-bronchial obstructing device that controls biological interaction with the patient
US6440164B1 (en) 1999-10-21 2002-08-27 Scimed Life Systems, Inc. Implantable prosthetic valve
US6439233B1 (en) 1999-02-01 2002-08-27 ADEVA Medical Gesellschaft für Entwicklung und Vertrieb von Medizinischen Implantat-Artikeln mbH Tracheal stoma valve
US20020123749A1 (en) 2001-03-01 2002-09-05 Jain Mudit K. Ablation catheter with transducer for providing one or more of pressure, temperature and fluid flow data for use in controlling ablation therapy
US6447530B1 (en) 1996-11-27 2002-09-10 Scimed Life Systems, Inc. Atraumatic anchoring and disengagement mechanism for permanent implant device
US6454754B1 (en) 1998-10-29 2002-09-24 Steven R. Frank Respiratory infection treatment device
US6454727B1 (en) 1998-03-03 2002-09-24 Senorx, Inc. Tissue acquisition system and method of use
US20020138135A1 (en) 2001-03-21 2002-09-26 Duerig Thomas W. Stent-based venous valves
US6458076B1 (en) 2000-02-01 2002-10-01 5 Star Medical Multi-lumen medical device
US20020147462A1 (en) 2000-09-11 2002-10-10 Closure Medical Corporation Bronchial occlusion method and apparatus
US6471979B2 (en) 1999-12-29 2002-10-29 Estrogen Vascular Technology, Llc Apparatus and method for delivering compounds to a living organism
WO2002087447A1 (en) 2001-04-27 2002-11-07 Rex Medical, L.P. Surgical biopsy device
WO2002056794A3 (en) 2001-01-18 2002-11-07 Brigham & Womens Hospital Prosthetic device for respiratory patients
US6485436B1 (en) 2000-08-10 2002-11-26 Csaba Truckai Pressure-assisted biopsy needle apparatus and technique
WO2002094087A1 (en) 2000-10-27 2002-11-28 Pulmonx Sheath and method for reconfiguring lung viewing scope
US6493589B1 (en) 1998-05-07 2002-12-10 Medtronic, Inc. Methods and apparatus for treatment of pulmonary conditions
US6491706B1 (en) 2001-07-10 2002-12-10 Spiration, Inc. Constriction device including fixation structure
WO2002047575A3 (en) 2000-12-15 2002-12-12 Angiomed Ag Stent with valve
WO2002022053A3 (en) 2000-09-18 2002-12-27 Endotex Interventional Sys Inc Apparatus for delivering endoluminal prostheses and methods of making and using them
WO2003003946A1 (en) 2001-07-03 2003-01-16 Boston Scientific Limited Eptfe graft with axial elongation properties
US20030013935A1 (en) 2001-07-10 2003-01-16 Spiration, Inc. Constriction device viewable under X ray fluoroscopy
US20030018344A1 (en) 2001-07-19 2003-01-23 Olympus Optical Co., Ltd. Medical device and method of embolizing bronchus or bronchiole
US20030018327A1 (en) 2001-07-20 2003-01-23 Csaba Truckai Systems and techniques for lung volume reduction
US6510846B1 (en) 1999-12-23 2003-01-28 O'rourke Sam Sealed back pressure breathing device
US6514290B1 (en) 2000-03-31 2003-02-04 Broncus Technologies, Inc. Lung elastic recoil restoring or tissue compressing device and method
US20030024527A1 (en) 2001-08-03 2003-02-06 Integrated Vascular Systems, Inc. Lung assist apparatus and methods for use
US20030050648A1 (en) 2001-09-11 2003-03-13 Spiration, Inc. Removable lung reduction devices, systems, and methods
US20030051733A1 (en) 2001-09-10 2003-03-20 Pulmonx Method and apparatus for endobronchial diagnosis
US20030055331A1 (en) 2001-09-11 2003-03-20 Pulmonx Methods of endobronchial diagnosis using imaging
US6540782B1 (en) 2000-02-02 2003-04-01 Robert V. Snyders Artificial heart valve
US6544291B2 (en) 1997-12-09 2003-04-08 Thomas V. Taylor Sutureless gastroesophageal anti-reflux valve prosthesis and tool for peroral implantation thereof
US20030070682A1 (en) 2001-10-11 2003-04-17 Wilson Peter M. Bronchial flow control devices and methods of use
US6551255B2 (en) 2000-10-16 2003-04-22 Sanarus Medical, Inc. Device for biopsy of tumors
WO2003034927A1 (en) 2001-10-25 2003-05-01 Spiration, Inc. Bronchial obstruction device deployment system and method
US20030083730A1 (en) 2001-10-25 2003-05-01 Scimed Life Systems, Inc. Loading cartridge for self-expanding stent
GB2348138B (en) 1999-02-18 2003-05-07 Tokendo Method and apparatus for positioning tracheal/bronchial endoprostheses
WO2003047468A1 (en) 2001-10-11 2003-06-12 Percutaneous Valve Technologies Implantable prosthetic valve
US20030109869A1 (en) 1998-10-28 2003-06-12 Shadduck John H. Medical instrument working end and method for endoluminal treatments
US20030125763A1 (en) 1990-02-07 2003-07-03 Mcinnes Peter R. Readily exchangeable perfusion dilatation catheter
US6589240B2 (en) 2001-08-28 2003-07-08 Rex Medical, L.P. Tissue biopsy apparatus with collapsible cutter
US20030127090A1 (en) 2001-11-14 2003-07-10 Emphasys Medical, Inc. Active pump bronchial implant devices and methods of use thereof
US6600307B2 (en) 2000-03-02 2003-07-29 Sarnoff Corporation Method and apparatus for measuring true transmitted power using a broadband dual directional coupler
US6599304B1 (en) * 1997-02-28 2003-07-29 Lumend, Inc. Methods and apparatus for treating vascular occlusions
US20030154988A1 (en) 2002-02-21 2003-08-21 Spiration, Inc. Intra-bronchial device that provides a medicant intra-bronchially to the patient
US20030158515A1 (en) 2002-02-21 2003-08-21 Spiration, Inc. Device and method for intra-bronchial provision of a therapeutic agent
US20030167065A1 (en) 2002-03-01 2003-09-04 Arvik Enterprises, Llc Blood vessel occlusion device
US6620095B2 (en) 2000-12-22 2003-09-16 Syde A. Taheri Cradle-assisted myocardial repair and treatment
US20030181890A1 (en) 2002-03-22 2003-09-25 Schulze Dale R. Medical device that removably attaches to a bodily organ
US20030181922A1 (en) 2002-03-20 2003-09-25 Spiration, Inc. Removable anchored lung volume reduction devices and methods
WO2003079944A1 (en) 2002-03-20 2003-10-02 Spiration, Inc. Removable anchored lung volume reduction devices and methods
US6632239B2 (en) 2001-10-02 2003-10-14 Spiration, Inc. Constriction device including reinforced suture holes
US20030199888A1 (en) 2000-10-17 2003-10-23 Aesculap Ag & Co. Kg Aneurysm clip
US6638285B2 (en) 2001-04-16 2003-10-28 Shlomo Gabbay Biological tissue strip and system and method to seal tissue
US20030212337A1 (en) 2002-05-09 2003-11-13 Spiration, Inc. Automated provision of information related to air evacuation from a chest cavity
US20030225445A1 (en) 2002-05-14 2003-12-04 Derus Patricia M. Surgical stent delivery devices and methods
WO2003099164A1 (en) 2002-05-28 2003-12-04 Emphasys Medical, Inc. Implantable bronchial isolation devices and lung treatment methods
US20030228344A1 (en) 2002-03-08 2003-12-11 Fields Antony J. Methods and devices for inducing collapse in lung regions fed by collateral pathways
US6669724B2 (en) 2001-06-05 2003-12-30 M.I. Tech Co. Ltd. Medical stent
WO2002069808A9 (en) 2000-11-06 2003-12-31 Suros Surgical Systems Inc Biopsy apparatus
US6682250B2 (en) 2001-11-07 2004-01-27 Lockheed Martin Corporation Position-adjustable fastening apparatus and method
US20040024356A1 (en) 2002-07-31 2004-02-05 Don Tanaka Long term oxygen therapy system
US20040039443A1 (en) 1999-06-30 2004-02-26 Solem Jan Otto Method and device for treatment of mitral insufficiency
US20040040555A1 (en) 2002-08-28 2004-03-04 Don Tanaka Collateral ventilation bypass trap system
US20040060563A1 (en) 2001-03-02 2004-04-01 Alan Rapacki Bronchial flow control devices and methods of use
WO2003088820A8 (en) 2002-04-19 2004-04-08 Broncus Tech Inc Devices for maintaining surgically created openings
US6746686B2 (en) 2000-01-24 2004-06-08 Biocompatibles Uk Limited Coated implants
US20040127912A1 (en) 2002-12-31 2004-07-01 Dmitry Rabkin Stent delivery system
WO2003078579A3 (en) 2002-03-11 2004-07-15 Aeris Therapeutics Inc Compositions and methods for treating emphysema
US20040143282A1 (en) 2002-05-17 2004-07-22 Dillard David H. Methods of achieving lung volume reduction with removable anchored devices
US20040143283A1 (en) 2003-01-17 2004-07-22 Mcgill Scott Inflation adaptor and method of use
WO2004010845A9 (en) 2002-07-26 2004-09-16 Emphasys Medical Inc Bronchial flow control devices with membrane seal
US20040200484A1 (en) 2003-04-08 2004-10-14 Springmeyer Steven C. Bronchoscopic lung volume reduction method
US20040210306A1 (en) 2003-04-17 2004-10-21 Quijano Rodolfo C. Device for reduction of pressure effects of cardiac tricuspid valve regurgitation
US20040210248A1 (en) 2003-03-12 2004-10-21 Spiration, Inc. Apparatus, method and assembly for delivery of intra-bronchial devices
US20040211434A1 (en) 2002-07-05 2004-10-28 Broncus Technologies, Inc. Extrapleural airway device and method
JP2004535887A (en) 2001-07-26 2004-12-02 エル. フィリップス、バン Socket insert with bladder system
US20040244802A1 (en) 2003-06-03 2004-12-09 Don Tanaka Lung reduction system
US6852108B2 (en) 2002-05-14 2005-02-08 Spiration, Inc. Apparatus and method for resecting and removing selected body tissue from a site inside a patient
WO2005013835A1 (en) 2003-08-08 2005-02-17 Spiration, Inc. Bronchoscopic repair of air leaks in a lung
US20050080434A1 (en) 2003-10-08 2005-04-14 Cedars-Sinai Medical Center Laparoscopic retractable dissector and suture and needle passer
US20050096721A1 (en) 2003-10-29 2005-05-05 Mangin Stephen P. Apparatus with visual marker for guiding deployment of implantable prosthesis
US6904909B2 (en) 2000-03-04 2005-06-14 Emphasys Medical, Inc. Methods and devices for use in performing pulmonary procedures
US20050137611A1 (en) 2001-09-04 2005-06-23 Broncus Technologies, Inc. Methods and devices for maintaining surgically created channels in a body organ
JP2005527297A (en) 2002-05-23 2005-09-15 オットー ボック ヘルスケアー エルピー Pulsating pressure chamber in the prosthesis
US6951571B1 (en) 2004-09-30 2005-10-04 Rohit Srivastava Valve implanting device
CA2308186C (en) 1997-10-24 2005-10-04 Theodore J. Century Intrapulmonary aerosolizer
US20050222580A1 (en) 2001-02-09 2005-10-06 Concentric Medical, Inc., A Delaware Corporation Methods and devices for delivering occlusion elements
US6958076B2 (en) 2001-04-16 2005-10-25 Biomedical Research Associates Inc. Implantable venous valve
US6958059B2 (en) 1996-05-20 2005-10-25 Medtronic Ave, Inc. Methods and apparatuses for drug delivery to an intravascular occlusion
US20050245894A1 (en) 1996-05-20 2005-11-03 Medtronic Vascular, Inc. Methods and apparatuses for drug delivery to an intravascular occlusion
US20050267323A1 (en) 2001-08-22 2005-12-01 Gerald Dorros Apparatus and methods for treating stroke and controlling cerebral flow characteristics
US6989027B2 (en) 2003-04-30 2006-01-24 Medtronic Vascular Inc. Percutaneously delivered temporary valve assembly
US20060064123A1 (en) 1998-02-06 2006-03-23 Possis Medical, Inc. Rapid exchange fluid jet thrombectomy device and method
WO2006034166A2 (en) 2004-09-17 2006-03-30 Cordis Neurovascular, Inc. Thin film metallic devices for plugging aneurysms or vessels
US20060100687A1 (en) 2004-11-10 2006-05-11 Creganna Technologies Limited Elongate tubular member for use in medical device shafts
US20060155217A1 (en) 2002-09-24 2006-07-13 Devore Lauri J Device and method for measuring the diameter of an air passageway
EP1078601B1 (en) 1999-08-24 2006-10-04 Spiration, Inc. Kit for lung volume reduction
US20060241745A1 (en) 2005-04-21 2006-10-26 Solem Jan O Blood flow controlling apparatus
WO2006124822A1 (en) 2005-05-13 2006-11-23 Alveolus, Inc. Delivery device allowing visual inspection of an intravascular site
US20060270940A1 (en) 2005-05-25 2006-11-30 Ross Tsukashima Self-condensing pH sensor and catheter apparatus
US7169140B1 (en) 1994-02-22 2007-01-30 Boston Scientific Scimed, Inc. Methods of using an intravascular balloon catheter in combination with an angioscope
US20070209204A1 (en) 2006-03-09 2007-09-13 Chase Daniel J Hose Assembly Process, Device, and Product-by-Process
US7273469B1 (en) 2003-12-31 2007-09-25 Advanced Cardiovascular Systems, Inc. Modified needle catheter for directional orientation delivery
US20070225747A1 (en) 2006-03-08 2007-09-27 Pulmonx Methods and devices to induce controlled atelectasis and hypoxic pulmonary vasoconstriction
US20070221230A1 (en) 2006-03-13 2007-09-27 David Thompson Minimally invasive lung volume reduction device and method
US20070232992A1 (en) 2006-03-31 2007-10-04 James Kutsko Articulable anchor
US7344553B2 (en) 2002-03-15 2008-03-18 Nmt Medical, Inc. Coupling system useful in placement of implants
US20080132989A1 (en) 2004-06-28 2008-06-05 Xtent, Inc. Devices and methods for controlling expandable prostheses during deployment
US20080149446A1 (en) 2006-12-22 2008-06-26 Raymond Schuurman Hydraulic clutch circuit
JP2009503031A (en) 2005-08-02 2009-01-29 シエル・インターナシヨナル・リサーチ・マートスハツペイ・ベー・ヴエー Method for preparing alkylene glycol
WO2009049261A1 (en) 2007-10-12 2009-04-16 Spiration, Inc. Valve loader method, system, and apparatus
US20090188508A1 (en) 2007-09-14 2009-07-30 Smith Jr A James Disposable medical mouthpiece appliance
WO2009135070A1 (en) 2008-05-01 2009-11-05 Spiration, Inc. Direct lung sensor systems, methods, and apparatuses
US20090292262A1 (en) 2007-10-12 2009-11-26 Martin Neal Adams Valve loader method, system, and apparatus
US7637934B2 (en) 2003-03-31 2009-12-29 Merit Medical Systems, Inc. Medical appliance optical delivery and deployment apparatus and method
US20100082089A1 (en) 2008-10-01 2010-04-01 Arshad Quadri Delivery system for vascular implant
US7704268B2 (en) 2004-05-07 2010-04-27 Nmt Medical, Inc. Closure device with hinges
US7862500B2 (en) 2002-08-01 2011-01-04 Cardiokinetix, Inc. Multiple partitioning devices for heart treatment
US7913698B2 (en) 2004-11-16 2011-03-29 Uptake Medical Corp. Device and method for lung treatment
US8192478B2 (en) 1999-08-09 2012-06-05 Cardiokinetix, Inc. System for improving cardiac function
WO2012158152A1 (en) 2011-05-13 2012-11-22 Spiration, Inc. Deployment catheter
JP2013107784A (en) 2011-11-18 2013-06-06 Shinetsu Quartz Prod Co Ltd Non-doped white fluorescent synthetic silica glass
US8711809B2 (en) 2007-04-27 2014-04-29 Blackberry Limited Method and system for efficient DRX operation during handover in LTE

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US149213A (en) * 1874-03-31 Improvement in tire-tighteners
US154625A (en) * 1874-09-01 Improvement in plug-tobacco
US154585A (en) * 1874-09-01 Improvement in valves for engines
US112104A (en) * 1871-02-28 Improvement in toy propellers
US128433A (en) * 1872-06-25 Improvement in bakers ovens
US110314A (en) * 1870-12-20 Improvement in thermometers
US145590A (en) * 1873-12-16 Improvement in boot and shoe tips
US110313A (en) * 1870-12-20 Improvement in boiler-furnaces
US105334A (en) * 1870-07-12 Improvement in reversible knob-latches
US1036642A (en) * 1909-06-26 1912-08-27 American Steel & Wire Co Reel.
US1151729A (en) * 1915-01-20 1915-08-31 William H Tigerman Truck.
US2140211A (en) * 1936-09-03 1938-12-13 Charles G Shaw Tap sole blank
DE4006961A1 (en) * 1990-03-06 1991-09-12 Messerschmitt Boelkow Blohm explosive charge
AU619708B1 (en) * 1990-06-22 1992-01-30 Fujitsu Limited Toner
US6273907B1 (en) 1997-04-07 2001-08-14 Broncus Technologies, Inc. Bronchial stenter
US6995675B2 (en) * 1998-03-09 2006-02-07 Curkendall Leland D Method and system for agricultural data collection and management
JP2002025781A (en) * 2000-07-07 2002-01-25 Nec Corp Organic el element and its manufacturing method
US20030195385A1 (en) * 2002-04-16 2003-10-16 Spiration, Inc. Removable anchored lung volume reduction devices and methods
US20040010209A1 (en) * 2002-07-15 2004-01-15 Spiration, Inc. Device and method for measuring the diameter of an air passageway

Patent Citations (656)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2115298A (en) 1937-04-16 1938-04-26 Roderick F Brown Suction tonsillectome
US2479805A (en) 1946-08-15 1949-08-23 Toledo Engineering Company Inc Method of and apparatus for feeding batch materials
US2728225A (en) 1953-03-12 1955-12-27 Herbert E Skibitzke Thermal flowmeter
US2832078A (en) 1956-10-17 1958-04-29 Battelle Memorial Institute Heart valve
US2981254A (en) 1957-11-12 1961-04-25 Edwin G Vanderbilt Apparatus for the gas deflation of an animal's stomach
US3320972A (en) 1964-04-16 1967-05-23 Roy F High Prosthetic tricuspid valve and method of and device for fabricating same
US3370305A (en) 1965-05-28 1968-02-27 Goott Bernard Heart valve with magnetic hinge means
US3472230A (en) 1966-12-19 1969-10-14 Fogarty T J Umbrella catheter
US3617060A (en) 1967-04-10 1971-11-02 Warren Iezzi Pneumothorox-inducing hunting arrow
US3445916A (en) 1967-04-19 1969-05-27 Rudolf R Schulte Method for making an anatomical check valve
US3540431A (en) 1968-04-04 1970-11-17 Kazi Mobin Uddin Collapsible filter for fluid flowing in closed passageway
US3671979A (en) 1969-09-23 1972-06-27 Univ Utah Catheter mounted artificial heart valve for implanting in close proximity to a defective natural heart valve
US3760808A (en) 1969-12-01 1973-09-25 K Bleuer Tampon applicator assembly
US3657744A (en) 1970-05-08 1972-04-25 Univ Minnesota Method for fixing prosthetic implants in a living body
US3683913A (en) 1970-10-05 1972-08-15 Deknatel Inc Underwater drainage apparatus with air flow meters
US3788327A (en) 1971-03-30 1974-01-29 H Donowitz Surgical implant device
US3757783A (en) 1971-09-24 1973-09-11 Sherwood Medical Ind Inc Suction drainage apparatus
US3874388A (en) 1973-02-12 1975-04-01 Ochsner Med Found Alton Shunt defect closure system
US4014318A (en) 1973-08-20 1977-03-29 Dockum James M Circulatory assist device and system
US3889657A (en) 1974-02-12 1975-06-17 Gomco Surgical Mfg Co Uterine aspirating curette
US3962917A (en) 1974-07-03 1976-06-15 Minato Medical Science Co., Ltd. Respirometer having thermosensitive elements on both sides of a hot wire
USRE31040E (en) 1975-04-24 1982-09-28 St. Jude Medical, Inc. Heart valve prosthesis
US4084268A (en) 1976-04-22 1978-04-18 Shiley Laboratories, Incorporated Prosthetic tissue heart valve
JPS6010740Y2 (en) 1976-08-12 1985-04-11 アイダエンジニアリング株式会社 rotary clamper
US4040428A (en) 1976-08-30 1977-08-09 The Aro Corporation Control valves for tracheotomy patient or laryngeal prosthesis
US4056854A (en) 1976-09-28 1977-11-08 The United States Of America As Represented By The Department Of Health, Education And Welfare Aortic heart valve catheter
US4086665A (en) 1976-12-16 1978-05-02 Thermo Electron Corporation Artificial blood conduit
US4250873A (en) 1977-04-26 1981-02-17 Richard Wolf Gmbh Endoscopes
US4218782A (en) 1977-05-25 1980-08-26 Biocoating Anpartsselskab Heart valve prosthesis and method for the production thereof
US4212463A (en) 1978-02-17 1980-07-15 Pratt Enoch B Humane bleeder arrow
US4205282A (en) 1978-08-21 1980-05-27 Westinghouse Electric Corp. Phase shifting circuit element
US4222126A (en) 1978-12-14 1980-09-16 The United States Of America As Represented By The Secretary Of The Department Of Health, Education & Welfare Unitized three leaflet heart valve
US4267839A (en) 1979-09-12 1981-05-19 Repromed, Inc. Surgical instrument for use in reversible sterilization or permanent occlusion procedures
SU852321A1 (en) 1979-10-02 1981-08-07 Второй Московский Ордена Ленинагосударственный Медицинский Ин-Ститут Им. H.И.Пирогова Method of treating acute purulent diseases of lungs and pleura of children
US4301810A (en) 1980-02-29 1981-11-24 City Of Hope National Medical Center Ventilatory muscle training apparatus
US4393879A (en) 1980-04-11 1983-07-19 Milex Products, Inc. Tissue-collecting apparatus
US4850999A (en) 1980-05-24 1989-07-25 Institute Fur Textil-Und Faserforschung Of Stuttgart Flexible hollow organ
US4808183A (en) 1980-06-03 1989-02-28 University Of Iowa Research Foundation Voice button prosthesis and method for installing same
US4302854A (en) 1980-06-04 1981-12-01 Runge Thomas M Electrically activated ferromagnetic/diamagnetic vascular shunt for left ventricular assist
GB2082071B (en) 1980-06-06 1984-07-11 Elliott Donald Paul Chest drainage
US4483200A (en) 1981-01-19 1984-11-20 Anima Corporation Thermal pulse flowmeter
US4339831A (en) 1981-03-27 1982-07-20 Medtronic, Inc. Dynamic annulus heart valve and reconstruction ring
US4403616A (en) 1981-06-09 1983-09-13 K-Med, Inc. Expiratory breathing exercise device
US4402445A (en) 1981-10-09 1983-09-06 United States Surgical Corporation Surgical fastener and means for applying same
US4533137A (en) 1982-01-19 1985-08-06 Healthscan Inc. Pulmonary training method
JPS58163332U (en) 1982-04-27 1983-10-31 株式会社豊田自動織機製作所 Rear confirmation mirror device for forklift
US4456016A (en) 1982-07-01 1984-06-26 Trutek Research, Inc. Inhalation valve
US4569674A (en) 1982-08-03 1986-02-11 Stryker Corporation Continuous vacuum wound drainage system
US4888015A (en) 1982-08-20 1989-12-19 Domino Rudolph S Method of replacing an eye lens
US4654029A (en) 1982-12-13 1987-03-31 Howmedica, Inc. Electronic drainage system
US4592741A (en) 1982-12-29 1986-06-03 Vincent Michel J Medical apparatus designed for the aspiration of phneumothorax
US4512338A (en) 1983-01-25 1985-04-23 Balko Alexander B Process for restoring patency to body vessels
US5562728A (en) 1983-12-09 1996-10-08 Endovascular Tech Inc Endovascular grafting apparatus, system and method and devices for use therewith
US4601465A (en) 1984-03-22 1986-07-22 Roy Jean Yves Device for stimulating the human respiratory system
US4727873A (en) 1984-04-17 1988-03-01 Mobin Uddin Kazi Embolus trap
US4583541A (en) 1984-05-07 1986-04-22 Barry Joseph P Sternal stabilization device
US5135531A (en) 1984-05-14 1992-08-04 Surgical Systems & Instruments, Inc. Guided atherectomy system
US4619246A (en) 1984-05-23 1986-10-28 William Cook, Europe A/S Collapsible filter basket
US4610256A (en) 1984-09-25 1986-09-09 Utah Medical Products, Inc. Pressure transducer
US4610256B1 (en) 1984-09-25 1988-06-21
US4685908A (en) 1984-10-18 1987-08-11 Bioresearch Ithaca Inc. Device for detecting increased pressure in pleural cavity
US4684363A (en) 1984-10-31 1987-08-04 American Hospital Supply Corporation Rapidly inflatable balloon catheter and method
US4819664A (en) 1984-11-15 1989-04-11 Stefano Nazari Device for selective bronchial intubation and separate lung ventilation, particularly during anesthesia, intensive therapy and reanimation
US4582058A (en) 1984-11-26 1986-04-15 Bivona, Inc. Tracheostoma valves
US4732152A (en) 1984-12-05 1988-03-22 Medinvent S.A. Device for implantation and a method of implantation in a vessel using such device
US4759758A (en) 1984-12-07 1988-07-26 Shlomo Gabbay Prosthetic heart valve
US4881939A (en) 1985-02-19 1989-11-21 The Johns Hopkins University Implantable helical cuff
US4654027A (en) 1985-10-30 1987-03-31 Dragan William B Vascular dilating device
US4681110A (en) 1985-12-02 1987-07-21 Wiktor Dominik M Catheter arrangement having a blood vessel liner, and method of using it
US4710192A (en) 1985-12-30 1987-12-01 Liotta Domingo S Diaphragm and method for occlusion of the descending thoracic aorta
SU1371700A1 (en) 1986-02-21 1988-02-07 МВТУ им.Н.Э.Баумана Prosthesis of heart valve
US4896668A (en) 1986-04-10 1990-01-30 Peters Plate set for osteal fixation, equipped with suture strands
US4832680A (en) 1986-07-03 1989-05-23 C.R. Bard, Inc. Apparatus for hypodermically implanting a genitourinary prosthesis
US4795449A (en) 1986-08-04 1989-01-03 Hollister Incorporated Female urinary incontinence device
US4822354A (en) 1986-09-02 1989-04-18 Elosegui Ignacio M Mechanical valvular prothesis for use in cardiac surgery
US4745925A (en) 1986-10-06 1988-05-24 Dietz Henry G Optoelectronic inhalation sensor for monitoring inhalation and for inhalation therapy
US5300050A (en) 1986-10-07 1994-04-05 Deknatel Technology Corporation Drainage device
US4852568A (en) 1987-02-17 1989-08-01 Kensey Nash Corporation Method and apparatus for sealing an opening in tissue of a living being
US4799311A (en) 1987-02-26 1989-01-24 Matsutani Seisakusho Co., Ltd. Apparatus for attaching suture to surgical needle
USRE35225E (en) 1987-03-02 1996-04-30 Atrium Medical Corporation Fluid recovery system
US4908028A (en) 1987-03-20 1990-03-13 Jean Colon Valve incorporating at least one rocking flap with respect to elastic pivots
WO1988009683A1 (en) 1987-06-10 1988-12-15 Kletschka Harold D An angioplasty device
SU1593651A1 (en) 1987-07-07 1990-09-23 1-Й Московский Медицинский Институт Им.И.М.Сеченова Artery prosthesis
US4934999A (en) 1987-07-28 1990-06-19 Paul Bader Closure for a male urethra
US4852552A (en) 1987-09-03 1989-08-01 Pilling Co. Sternal retractor
US4936823A (en) 1988-05-04 1990-06-26 Triangle Research And Development Corp. Transendoscopic implant capsule
US5002772A (en) 1988-05-31 1991-03-26 Pfizer Inc. Gastric retention system for controlled drug release
US4830003A (en) 1988-06-17 1989-05-16 Wolff Rodney G Compressive stent and delivery system
US4870975A (en) 1988-07-05 1989-10-03 Scott Cronk Suction canister assembly for the collection of body fluids and tissue specimens
US4920978A (en) 1988-08-31 1990-05-01 Triangle Research And Development Corporation Method and apparatus for the endoscopic treatment of deep tumors using RF hyperthermia
US5413599A (en) 1988-09-20 1995-05-09 Nippon Zeon Co., Ltd. Medical valve apparatus
WO1990003152A1 (en) 1988-09-24 1990-04-05 John Considine Electro-surgical apparatus for removing tumours from hollow organs of the body
US4846836A (en) 1988-10-03 1989-07-11 Reich Jonathan D Artificial lower gastrointestinal valve
US4877025A (en) 1988-10-06 1989-10-31 Hanson Donald W Tracheostomy tube valve apparatus
US5116564A (en) 1988-10-11 1992-05-26 Josef Jansen Method of producing a closing member having flexible closing elements, especially a heart valve
US4984581A (en) 1988-10-12 1991-01-15 Flexmedics Corporation Flexible guide having two-way shape memory alloy
US4973047A (en) 1988-12-09 1990-11-27 Erik Norell Therapeutic device for lung exercise
US5800339A (en) 1989-02-09 1998-09-01 Opticon Medical Inc. Urinary control valve
US4968294A (en) 1989-02-09 1990-11-06 Salama Fouad A Urinary control valve and method of using same
US5350388A (en) 1989-03-07 1994-09-27 Albert Einstein College Of Medicine Of Yeshiva University Hemostasis apparatus and method
US5186711A (en) 1989-03-07 1993-02-16 Albert Einstein College Of Medicine Of Yeshiva University Hemostasis apparatus and method
US5135488A (en) 1989-03-17 1992-08-04 Merit Medical Systems, Inc. System and method for monitoring, displaying and recording balloon catheter inflation data
US5111823A (en) 1989-04-20 1992-05-12 National Fertility Institute Apparatus and method for generating echographic images
US5500014A (en) 1989-05-31 1996-03-19 Baxter International Inc. Biological valvular prothesis
US5352240A (en) 1989-05-31 1994-10-04 Promedica International, Inc. Human heart valve replacement with porcine pulmonary valve
US4979505A (en) 1989-06-06 1990-12-25 Cox Everard F Tracheal tube
US5314473A (en) 1989-07-20 1994-05-24 Godin Norman J Prosthesis for preventing gastric reflux into the esophagus
US5562608A (en) 1989-08-28 1996-10-08 Biopulmonics, Inc. Apparatus for pulmonary delivery of drugs with simultaneous liquid lavage and ventilation
US6242472B1 (en) 1989-08-28 2001-06-05 Alliance Pharmaceutical Corp. Methods for the pulmonary delivery of biological agents
US5019086A (en) 1989-09-12 1991-05-28 Neward Theodore C Manipulable vacuum extractor for childbirth and method of using the same
US4995872A (en) 1989-10-04 1991-02-26 Ferrara Janice J Expandable catheter and bridge device
US5038621A (en) 1989-11-06 1991-08-13 Bicore Monitoring Systems Variable area obstruction gas flow meter
US5033312A (en) 1989-11-06 1991-07-23 Bicore Monitoring Systems Gas flow meter housing
US5797907A (en) 1989-11-06 1998-08-25 Mectra Labs, Inc. Electrocautery cutter
US5339805A (en) 1989-11-08 1994-08-23 Parker Jeffrey D Blind orolaryngeal and oroesophageal guiding and aiming device
US5061274A (en) 1989-12-04 1991-10-29 Kensey Nash Corporation Plug device for sealing openings and method of use
US20030125763A1 (en) 1990-02-07 2003-07-03 Mcinnes Peter R. Readily exchangeable perfusion dilatation catheter
US5514153A (en) 1990-03-02 1996-05-07 General Surgical Innovations, Inc. Method of dissecting tissue layers
US5127412A (en) 1990-03-14 1992-07-07 Cosmetto Aristodeme J Skin tensioning
US5158548A (en) 1990-04-25 1992-10-27 Advanced Cardiovascular Systems, Inc. Method and system for stent delivery
US5593413A (en) 1990-05-14 1997-01-14 Medisys Technologies, Inc. Device for assisting childbirth
US5840081A (en) 1990-05-18 1998-11-24 Andersen; Henning Rud System and method for implanting cardiac valves
US6168614B1 (en) 1990-05-18 2001-01-02 Heartport, Inc. Valve prosthesis for implantation in the body
US5411552A (en) 1990-05-18 1995-05-02 Andersen; Henning R. Valve prothesis for implantation in the body and a catheter for implanting such valve prothesis
US5078739A (en) 1990-07-20 1992-01-07 Janus Biomedical, Inc. Bileaflet heart valve with external leaflets
US5197980A (en) 1990-08-14 1993-03-30 Gorshkov Jury V Cardiac valve prosthesis
US5092781A (en) 1990-11-08 1992-03-03 Amp Incorporated Electrical connector using shape memory alloy coil springs
WO1992010725A1 (en) 1990-12-11 1992-06-25 Abbey Biosystems Limited Hot wire anemometer
US5116360A (en) 1990-12-27 1992-05-26 Corvita Corporation Mesh composite graft
US5059208A (en) 1991-02-04 1991-10-22 Helix Medical, Inc. Adjustable tracheostoma valve
US5353470A (en) 1991-04-18 1994-10-11 Ryobi Motor Products Corporation Horizontal canister vacuum
US5226429A (en) 1991-06-20 1993-07-13 Inamed Development Co. Laparoscopic gastric band and method
US5358518A (en) 1991-06-25 1994-10-25 Sante Camilli Artificial venous valve
US5147369A (en) 1991-07-01 1992-09-15 Wagner Michael A Forceps and method for nuclear fragment removal
US5161524A (en) 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
US5171299A (en) 1991-08-02 1992-12-15 Baxter International Inc. Balloon catheter inflation pressure and diameter display apparatus and method
US5281229A (en) 1991-08-09 1994-01-25 Neward Theodore C Obstetrical vacuum extractor
US5207702A (en) 1991-08-14 1993-05-04 Pearl Michael L Method and apparatus for handling hygroscopic dilators
US5151105A (en) 1991-10-07 1992-09-29 Kwan Gett Clifford Collapsible vessel sleeve implant
US5662713A (en) 1991-10-09 1997-09-02 Boston Scientific Corporation Medical stents for body lumens exhibiting peristaltic motion
US5876445A (en) 1991-10-09 1999-03-02 Boston Scientific Corporation Medical stents for body lumens exhibiting peristaltic motion
US5197485A (en) 1991-10-15 1993-03-30 Pilling Co. Method and apparatus for sampling aortic plaque
US5741271A (en) 1991-11-05 1998-04-21 Nakao; Naomi L. Surgical retrieval assembly and associated method
US5123919A (en) 1991-11-21 1992-06-23 Carbomedics, Inc. Combined prosthetic aortic heart valve and vascular graft
US5197963A (en) 1991-12-02 1993-03-30 Everest Medical Corporation Electrosurgical instrument with extendable sheath for irrigation and aspiration
US5445626A (en) 1991-12-05 1995-08-29 Gigante; Luigi Valve operated catheter for urinary incontinence and retention
US5391205A (en) 1991-12-17 1995-02-21 Knight; Roy F. Tracheoesophageal voice prosthesis
US5275169A (en) 1992-01-15 1994-01-04 Innovation Associates Apparatus and method for determining physiologic characteristics of body lumens
US5255687A (en) 1992-01-21 1993-10-26 Mckenna Charles L Zero dead space respiratory exercise valve
US6077291A (en) 1992-01-21 2000-06-20 Regents Of The University Of Minnesota Septal defect closure device
US5283063A (en) 1992-01-31 1994-02-01 Eagle Vision Punctum plug method and apparatus
US5509900A (en) 1992-03-02 1996-04-23 Kirkman; Thomas R. Apparatus and method for retaining a catheter in a blood vessel in a fixed position
US5409444A (en) 1992-03-04 1995-04-25 Kensey Nash Corporation Method and apparatus to reduce injury to the vascular system
US5421325A (en) 1992-04-30 1995-06-06 Cinberg; James Z. Endotracheal tube assembly and related method
US5342298A (en) 1992-07-31 1994-08-30 Advanced Cardiovascular Systems, Inc. Automated fluid pressure control system
US5382261A (en) 1992-09-01 1995-01-17 Expandable Grafts Partnership Method and apparatus for occluding vessels
US5649953A (en) 1992-09-28 1997-07-22 Bentex Trading S.A. Kit for medical use composed of a filter and a device for placing it in the vessel
US5356412A (en) 1992-10-09 1994-10-18 United States Surgical Corporation Sternum buckle with rotational engagement and method of closure
US5409019A (en) 1992-10-30 1995-04-25 Wilk; Peter J. Coronary artery by-pass method
US5484444A (en) 1992-10-31 1996-01-16 Schneider (Europe) A.G. Device for the implantation of self-expanding endoprostheses
US5947997A (en) 1992-11-25 1999-09-07 William Cook Europe A/S Closure prothesis for transcatheter placement
US5810837A (en) 1992-12-16 1998-09-22 Schneider (Europe) A.G. Device for the implantation of a self-expanding endoprosthesis
US5366475A (en) 1992-12-21 1994-11-22 Shatzu Health Products, Inc. Tragus acupressure clip
US5690644A (en) 1992-12-30 1997-11-25 Schneider (Usa) Inc. Apparatus for deploying body implantable stent
US5304199A (en) 1993-01-04 1994-04-19 Gene E. Myers Enterprises, Inc. Apparatus for arterial total occlusion plaque separation
US5411507A (en) 1993-01-08 1995-05-02 Richard Wolf Gmbh Instrument for implanting and extracting stents
US5459544A (en) 1993-02-01 1995-10-17 Konica Corporation Camera with a shape memory alloy member
JPH0819544B2 (en) 1993-02-05 1996-02-28 協和電線株式会社 Lead steel wire for electronic parts and manufacturing method thereof
US5797960A (en) 1993-02-22 1998-08-25 Stevens; John H. Method and apparatus for thoracoscopic intracardiac procedures
US5306234A (en) 1993-03-23 1994-04-26 Johnson W Dudley Method for closing an atrial appendage
US5370657A (en) 1993-03-26 1994-12-06 Scimed Life Systems, Inc. Recoverable thrombosis filter
US5603698A (en) 1993-04-13 1997-02-18 Boston Scientific Corporation Prosthesis delivery system
WO1994026175A1 (en) 1993-05-06 1994-11-24 Vitaphore Corporation Embolization device
US5562641A (en) 1993-05-28 1996-10-08 A Bromberg & Co. Ltd. Two way shape memory alloy medical stent
US5486154A (en) 1993-06-08 1996-01-23 Kelleher; Brian S. Endoscope
US5423830A (en) 1993-07-07 1995-06-13 Schneebaum; Cary W. Polyp retrieval method and associated instrument assembly
US5366478A (en) 1993-07-27 1994-11-22 Ethicon, Inc. Endoscopic surgical sealing device
US5507797A (en) 1993-08-20 1996-04-16 Sumitomo Bakelite Company Limited Slidable kit for endoscopic ligation
US5507754A (en) 1993-08-20 1996-04-16 United States Surgical Corporation Apparatus and method for applying and adjusting an anchoring device
US6142957A (en) 1993-09-20 2000-11-07 Boston Scientific Corporation Multiple biopsy sampling device
US5383470A (en) 1993-09-20 1995-01-24 Steve Novak Portable spirometer
US6045560A (en) 1993-10-06 2000-04-04 United States Surgical Corporation Surgical stapling apparatus with biocompatible surgical fabric
US5456689A (en) 1993-10-13 1995-10-10 Arnold J. Kresch Method and device for tissue resection
US5607469A (en) 1993-10-28 1997-03-04 Inocor Gmbh Bi-leaflet prosthetic heart valve
US6135729A (en) 1993-11-10 2000-10-24 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Blood pump bearing system
US5490860A (en) 1993-12-08 1996-02-13 Sofamor Danek Properties, Inc. Portable power cutting tool
US5415658A (en) 1993-12-14 1995-05-16 Pioneer Laboratories, Inc. Surgical cable loop connector
US5415660A (en) 1994-01-07 1995-05-16 Regents Of The University Of Minnesota Implantable limb lengthening nail driven by a shape memory alloy
US5772583A (en) 1994-01-21 1998-06-30 Wright; John T. M. Sternal retractor with attachments for mitral & tricuspid valve repair
EP0665029B1 (en) 1994-01-27 2000-11-02 The Kendall Company Esophageal-tracheal double lumen airway
US5398844A (en) 1994-01-31 1995-03-21 Boston Scientific Corporation Multiple ligating band dispenser
US6053877A (en) 1994-02-08 2000-04-25 Boston Scientific Corporation Movable sample tube multiple biopsy sampling device
US5503638A (en) 1994-02-10 1996-04-02 Bio-Vascular, Inc. Soft tissue stapling buttress
US5549628A (en) 1994-02-10 1996-08-27 Bio-Vascular, Inc. Soft tissue stapling buttress
US7169140B1 (en) 1994-02-22 2007-01-30 Boston Scientific Scimed, Inc. Methods of using an intravascular balloon catheter in combination with an angioscope
US5453090A (en) 1994-03-01 1995-09-26 Cordis Corporation Method of stent delivery through an elongate softenable sheath
US5392775A (en) 1994-03-22 1995-02-28 Adkins, Jr.; Claude N. Duckbill valve for a tracheostomy tube that permits speech
US5803078A (en) 1994-05-06 1998-09-08 Brauner; Mark E. Methods and apparatus for intrapulmonary therapy and drug administration
WO1995032018A1 (en) 1994-05-25 1995-11-30 Teirstein Paul S Body passageway closure apparatus and method
US5499995C1 (en) 1994-05-25 2002-03-12 Paul S Teirstein Body passageway closure apparatus and method of use
US5499995A (en) 1994-05-25 1996-03-19 Teirstein; Paul S. Body passageway closure apparatus and method of use
US5683451A (en) 1994-06-08 1997-11-04 Cardiovascular Concepts, Inc. Apparatus and methods for deployment release of intraluminal prostheses
US6350278B1 (en) 1994-06-08 2002-02-26 Medtronic Ave, Inc. Apparatus and methods for placement and repositioning of intraluminal prostheses
US5417226A (en) 1994-06-09 1995-05-23 Juma; Saad Female anti-incontinence device
US6079413A (en) 1994-06-17 2000-06-27 Trudell Medical Limited Catheter system for delivery of aerosolized medicine for use with pressurized propellant canister
US6673070B2 (en) 1994-06-24 2004-01-06 Curon Medical, Inc. Sphincter treatment apparatus
US20010034518A1 (en) 1994-06-24 2001-10-25 Curon Medical, Inc. Sphincter treatment apparatus
US6062575A (en) 1994-07-27 2000-05-16 Mednext, Inc. Tool shaft coupler
WO1996004875A1 (en) 1994-08-08 1996-02-22 Inbae Yoon Multifunctional devices having loop configured portions and collection systems for endoscopic surgical procedures and methods therefor
US5549626A (en) 1994-12-23 1996-08-27 New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Vena caval filter
US5755770A (en) 1995-01-31 1998-05-26 Boston Scientific Corporatiion Endovascular aortic graft
US5575293A (en) 1995-02-06 1996-11-19 Promex, Inc. Apparatus for collecting and staging tissue
US6083141A (en) 1995-02-10 2000-07-04 Hougen; Everett D. Portable respiratory exercise apparatus and method for using the same
US5647857A (en) 1995-03-16 1997-07-15 Endotex Interventional Systems, Inc. Protective intraluminal sheath
US5662622A (en) 1995-04-04 1997-09-02 Cordis Corporation Intravascular catheter
US5676671A (en) 1995-04-12 1997-10-14 Inoue; Kanji Device for introducing an appliance to be implanted into a catheter
US5693089A (en) 1995-04-12 1997-12-02 Inoue; Kanji Method of collapsing an implantable appliance
EP0743071A3 (en) 1995-04-24 1997-04-23 Haemonetics Corp Autotransfusion apparatus
US5752522A (en) 1995-05-04 1998-05-19 Cardiovascular Concepts, Inc. Lesion diameter measurement catheter and method
US6010511A (en) 1995-05-04 2000-01-04 Murphy; Richard Lesion diameter measurement catheter and method
WO1996034582A1 (en) 1995-05-05 1996-11-07 Angiomed Gmbh & Co. Medizintechnik Kg Endosphincter, set for releasably closing the urethra and process for inserting an endosphincter into the urethra
US6165179A (en) 1995-05-23 2000-12-26 Boston Scientific Corporation Vena cava delivery system
US5833694A (en) 1995-05-25 1998-11-10 Medtronic, Inc. Stent assembly and method of use
WO1996037167A1 (en) 1995-05-25 1996-11-28 Raychem Corporation Stent assembly
US6716208B2 (en) 1995-06-05 2004-04-06 Nephros Therapeutics, Inc. Implantable device and use therefor
US6312407B1 (en) 1995-06-05 2001-11-06 Medtronic Percusurge, Inc. Occlusion of a vessel
US20010001817A1 (en) 1995-06-05 2001-05-24 Humes H. David Implantable device and use therefor
US5645565A (en) 1995-06-13 1997-07-08 Ethicon Endo-Surgery, Inc. Surgical plug
US5902312A (en) 1995-07-03 1999-05-11 Frater; Dirk A. System for mounting bolster material on tissue staplers
US5766134A (en) 1995-07-18 1998-06-16 Atrion Medical Products, Inc. Autogenous bone specimen collector
US5810855A (en) 1995-07-21 1998-09-22 Gore Enterprise Holdings, Inc. Endoscopic device and method for reinforcing surgical staples
US5702409A (en) 1995-07-21 1997-12-30 W. L. Gore & Associates, Inc. Device and method for reinforcing surgical staples
US5697968A (en) 1995-08-10 1997-12-16 Aeroquip Corporation Check valve for intraluminal graft
US5660175A (en) 1995-08-21 1997-08-26 Dayal; Bimal Endotracheal device
US6213957B1 (en) 1995-09-08 2001-04-10 United States Surgical Corporation Apparatus and method for removing tissue
WO1997009932A1 (en) 1995-09-12 1997-03-20 Boston Scientific Corporation Stent delivery system
WO1997013471A1 (en) 1995-10-13 1997-04-17 Transvascular, Inc. A device, system and method for interstitial transvascular intervention
US6231587B1 (en) 1995-10-13 2001-05-15 Transvascular, Inc. Devices for connecting anatomical conduits such as vascular structures
JPH11513577A (en) 1995-10-13 1999-11-24 トランスバスキュラー インコーポレイテッド Apparatus, system and method for inter-tissue transluminal intervention
US6068638A (en) 1995-10-13 2000-05-30 Transvascular, Inc. Device, system and method for interstitial transvascular intervention
US6146384A (en) 1995-10-13 2000-11-14 Sdgi Holdings, Inc. Orthopedic fixation device and method of implantation
US5865724A (en) 1996-01-11 1999-02-02 Symbiosis Corp. Flexible microsurgical instruments incorporating a sheath having tactile and visual position indicators
US6327772B1 (en) 1996-01-30 2001-12-11 Medtronic, Inc. Method for fabricating a planar eversible lattice which forms a stent when everted
WO1997027893A1 (en) 1996-02-02 1997-08-07 Transvascular, Inc. Methods and apparatus for blocking flow through blood vessels
US5763979A (en) 1996-02-29 1998-06-09 The United States Of America As Represented By The Secretary Of The Navy Actuation system for the control of multiple shape memory alloy elements
US6174307B1 (en) 1996-03-29 2001-01-16 Eclipse Surgical Technologies, Inc. Viewing surgical scope for minimally invasive procedures
WO1997042871A1 (en) 1996-05-10 1997-11-20 Cardiovascular Concepts, Inc. Lesion diameter measurement catheter and method
US5980545A (en) 1996-05-13 1999-11-09 United States Surgical Corporation Coring device and method
US6958059B2 (en) 1996-05-20 2005-10-25 Medtronic Ave, Inc. Methods and apparatuses for drug delivery to an intravascular occlusion
US6325777B1 (en) 1996-05-20 2001-12-04 Medtronic Percusurge, Inc. Low profile catheter valve and inflation adaptor
US6325778B1 (en) 1996-05-20 2001-12-04 Medtronic Percusurge, Inc. Low profile catheter valve and inflation adaptor
WO1997044085A3 (en) 1996-05-20 1998-09-17 Percusurge Inc Low profile catheter valve
US20050245894A1 (en) 1996-05-20 2005-11-03 Medtronic Vascular, Inc. Methods and apparatuses for drug delivery to an intravascular occlusion
US6355014B1 (en) 1996-05-20 2002-03-12 Medtronic Percusurge, Inc. Low profile catheter valve
US6027525A (en) 1996-05-23 2000-02-22 Samsung Electronics., Ltd. Flexible self-expandable stent and method for making the same
US6428561B1 (en) 1996-06-05 2002-08-06 Astra Aktiebolag Biocompatible glue
US5855587A (en) 1996-06-13 1999-01-05 Chon-Ik Hyon Hole forming device for pierced earrings
US5797920A (en) 1996-06-14 1998-08-25 Beth Israel Deaconess Medical Center Catheter apparatus and method using a shape-memory alloy cuff for creating a bypass graft in-vivo
US5855601A (en) 1996-06-21 1999-01-05 The Trustees Of Columbia University In The City Of New York Artificial heart valve and method and device for implanting the same
US5911756A (en) 1996-06-26 1999-06-15 Novatech Intralaryngeal prosthesis
WO1998000840A1 (en) 1996-06-28 1998-01-08 Samsung Electronics Co., Ltd. Thin film magnetic head tip and manufacturing method therefor
US6123663A (en) 1996-07-04 2000-09-26 Rebuffat; Carlo Surgical appliance for the treatment of pulmonary emphysema
WO1998001084A1 (en) 1996-07-04 1998-01-15 Carlo Rebuffat Surgical appliance for the treatment of pulmonary emphysema
US6302893B1 (en) 1996-07-15 2001-10-16 Advanced Cardiovascular Systems, Inc. Self-expanding stent delivery system
US5669933A (en) 1996-07-17 1997-09-23 Nitinol Medical Technologies, Inc. Removable embolus blood clot filter
US20020077564A1 (en) 1996-07-29 2002-06-20 Farallon Medsystems, Inc. Thermography catheter
US6102885A (en) 1996-08-08 2000-08-15 Bass; Lawrence S. Device for suction-assisted lipectomy and method of using same
US5830217A (en) 1996-08-09 1998-11-03 Thomas J. Fogarty Soluble fixation device and method for stent delivery catheters
US6183520B1 (en) 1996-08-13 2001-02-06 Galt Laboratories, Inc. Method of maintaining urinary continence
WO1998008441A1 (en) 1996-08-29 1998-03-05 Ethicon Endo-Surgery Methods and devices for collection of soft tissue
US5810806A (en) 1996-08-29 1998-09-22 Ethicon Endo-Surgery Methods and devices for collection of soft tissue
US5725519A (en) 1996-09-30 1998-03-10 Medtronic Instent Israel Ltd. Stent loading device for a balloon catheter
US5702343A (en) 1996-10-02 1997-12-30 Acorn Medical, Inc. Cardiac reinforcement device
US5895387A (en) 1996-10-09 1999-04-20 Romulo Guerrero Method of craniofacial bone distraction
US5752965A (en) 1996-10-21 1998-05-19 Bio-Vascular, Inc. Apparatus and method for producing a reinforced surgical fastener suture line
US5769892A (en) 1996-10-22 1998-06-23 Mitroflow International Inc. Surgical stapler sleeve for reinforcing staple lines
WO1998019633A1 (en) 1996-11-06 1998-05-14 Percusurge, Inc. Apparatus and method for loading a stent on a catheter
US6447530B1 (en) 1996-11-27 2002-09-10 Scimed Life Systems, Inc. Atraumatic anchoring and disengagement mechanism for permanent implant device
US6102926A (en) 1996-12-02 2000-08-15 Angiotrax, Inc. Apparatus for percutaneously performing myocardial revascularization having means for sensing tissue parameters and methods of use
US5779649A (en) 1996-12-17 1998-07-14 Pabban Development, Inc. Surgical suction wand with filter
US6287334B1 (en) 1996-12-18 2001-09-11 Venpro Corporation Device for regulating the flow of blood through the blood system
US20010010017A1 (en) 1996-12-31 2001-07-26 Brice Letac Alve prosthesis for implantation in body channels
US5810809A (en) 1997-01-13 1998-09-22 Enhanced Orthopaedic Technologies, Inc. Arthroscopic shaver incorporating electrocautery
US6338728B1 (en) 1997-01-14 2002-01-15 Genzyme Corporation Chest drainage device having multiple operation indicators
US5989234A (en) 1997-01-14 1999-11-23 Deknatel Technology Corporation Device and system for draining a body cavity and methods related thereto
US5782896A (en) 1997-01-29 1998-07-21 Light Sciences Limited Partnership Use of a shape memory alloy to modify the disposition of a device within an implantable medical probe
US6193748B1 (en) 1997-02-12 2001-02-27 Schneider (Usa) Inc Occlusion device
US6599304B1 (en) * 1997-02-28 2003-07-29 Lumend, Inc. Methods and apparatus for treating vascular occlusions
US6135991A (en) 1997-03-06 2000-10-24 Percusurge, Inc. Aspiration method
WO1998039047A1 (en) 1997-03-06 1998-09-11 Percusurge, Inc. Aspiration system and method
US5817101A (en) 1997-03-13 1998-10-06 Schneider (Usa) Inc Fluid actuated stent delivery system
US5851232A (en) 1997-03-15 1998-12-22 Lois; William A. Venous stent
US6267775B1 (en) 1997-03-21 2001-07-31 Schneider (Usa) Inc. Self-expanding medical device for centering radioactive treatment sources in body vessels
US6083255A (en) 1997-04-07 2000-07-04 Broncus Technologies, Inc. Bronchial stenter
US6488673B1 (en) 1997-04-07 2002-12-03 Broncus Technologies, Inc. Method of increasing gas exchange of a lung
US6200333B1 (en) 1997-04-07 2001-03-13 Broncus Technologies, Inc. Bronchial stenter
US6634363B1 (en) 1997-04-07 2003-10-21 Broncus Technologies, Inc. Methods of treating lungs having reversible obstructive pulmonary disease
EP1157663A1 (en) 1997-04-30 2001-11-28 Sabanathan, Thirumani Occlusion device
GB2324729A (en) 1997-04-30 1998-11-04 Bradford Hospitals Nhs Trust Lung treatment device
WO1998048706A1 (en) 1997-04-30 1998-11-05 Bradford Hospitals Nhs Trust Occlusion device
US5957949A (en) 1997-05-01 1999-09-28 World Medical Manufacturing Corp. Percutaneous placement valve stent
US6245102B1 (en) 1997-05-07 2001-06-12 Iowa-India Investments Company Ltd. Stent, stent graft and stent valve
US5855597A (en) 1997-05-07 1999-01-05 Iowa-India Investments Co. Limited Stent valve and stent graft for percutaneous surgery
US6162245A (en) 1997-05-07 2000-12-19 Iowa-India Investments Company Limited Stent valve and stent graft
US5976158A (en) 1997-06-02 1999-11-02 Boston Scientific Corporation Method of using a textured ligating band
US6007575A (en) 1997-06-06 1999-12-28 Samuels; Shaun Laurence Wilkie Inflatable intraluminal stent and method for affixing same within the human body
WO1999001076A1 (en) 1997-07-02 1999-01-14 Broncus Technologies, Inc. Bleb reducer
US5876434A (en) 1997-07-13 1999-03-02 Litana Ltd. Implantable medical devices of shape memory alloy
US5954636A (en) 1997-07-15 1999-09-21 Schwartz; Roy E. Pediatric endotracheal tube with bronchial blocker and method for selectively blocking respiratory airflow to a pediatric patient's lung
US6010525A (en) 1997-08-01 2000-01-04 Peter M. Bonutti Method and apparatus for securing a suture
US5984965A (en) 1997-08-28 1999-11-16 Urosurge, Inc. Anti-reflux reinforced stent
US6632243B1 (en) 1997-09-16 2003-10-14 Emphasys Medical Inc. Body fluid flow control device
US20020077696A1 (en) 1997-09-16 2002-06-20 Gholam-Reza Zadno-Azizi Body fluid flow control device
US20020095209A1 (en) 1997-09-16 2002-07-18 Gholam-Reza Zadno-Azizi Body fluid flow control device
US20030199972A1 (en) 1997-09-16 2003-10-23 Gholam-Reza Zadno-Azizi Body fluid flow control device
US5954766A (en) 1997-09-16 1999-09-21 Zadno-Azizi; Gholam-Reza Body fluid flow control device
WO1999013801A1 (en) 1997-09-16 1999-03-25 Zadno Azizi Gholam Reza Body fluid flow control device
US6322522B1 (en) 1997-09-22 2001-11-27 Zimmon Science Corp. Apparatus for separable external serial collection, storage and processing of biopsy specimens
US5925063A (en) 1997-09-26 1999-07-20 Khosravi; Farhad Coiled sheet valve, filter or occlusive device and methods of use
CA2308186C (en) 1997-10-24 2005-10-04 Theodore J. Century Intrapulmonary aerosolizer
US6238334B1 (en) 1997-11-03 2001-05-29 Cardio Technologies, Inc. Method and apparatus for assisting a heart to pump blood
US6887256B2 (en) 1997-11-07 2005-05-03 Salviac Limited Embolic protection system
US20020052626A1 (en) 1997-11-07 2002-05-02 Paul Gilson Embolic protection system
WO1999026692A1 (en) 1997-11-20 1999-06-03 Percusurge, Inc. Low profile catheter valve and inflation adaptor
US6544291B2 (en) 1997-12-09 2003-04-08 Thomas V. Taylor Sutureless gastroesophageal anti-reflux valve prosthesis and tool for peroral implantation thereof
US6558429B2 (en) 1997-12-09 2003-05-06 Reflux Corporation Perorally insertable gastroesophageal anti-reflux valve prosthesis and tool for implantation thereof
US5976174A (en) 1997-12-15 1999-11-02 Ruiz; Carlos E. Medical hole closure device and methods of use
WO1999032040A1 (en) 1997-12-19 1999-07-01 Broncus Technologies, Inc. Bronchial stenter
US5957978A (en) 1997-12-22 1999-09-28 Hansa Medical Products, Inc. Valved fenestrated tracheotomy tube
FR2773702B1 (en) 1998-01-16 2000-04-07 Johnson & Johnson Internationa COMPRESSION DEVICE FOR HEMOSTASIS OF AN ORGAN, SUCH AS LIVER
US5944738A (en) 1998-02-06 1999-08-31 Aga Medical Corporation Percutaneous catheter directed constricting occlusion device
US20060064123A1 (en) 1998-02-06 2006-03-23 Possis Medical, Inc. Rapid exchange fluid jet thrombectomy device and method
WO1999042161A3 (en) 1998-02-19 1999-10-28 Percusurge Inc Low profile fluid delivery and sealing system for a catheter
WO1999042059A3 (en) 1998-02-19 1999-11-11 Percusurge Inc Occlusion of a vessel
US6849049B2 (en) 1998-02-25 2005-02-01 Ric Investments, Inc. Patient monitor and method of using same
US20020029004A1 (en) 1998-02-25 2002-03-07 Respironics, Inc. Patient monitor and method of using same
US6544192B2 (en) 1998-02-25 2003-04-08 Respironics, Inc. Patient monitor and method of using same
WO1998044854B1 (en) 1998-02-27 1998-11-19 Bronchial stenter
US6454727B1 (en) 1998-03-03 2002-09-24 Senorx, Inc. Tissue acquisition system and method of use
US6068635A (en) 1998-03-04 2000-05-30 Schneider (Usa) Inc Device for introducing an endoprosthesis into a catheter shaft
US6099551A (en) 1998-03-12 2000-08-08 Shelhigh, Inc. Pericardial strip and stapler assembly for dividing and sealing visceral tissues and method of use thereof
US20010012949A1 (en) 1998-03-13 2001-08-09 Forber Simon J. Covered self-expanding vascular occlusion device
US6589256B2 (en) 1998-03-13 2003-07-08 B. Braun Medical Sas Covered self-expanding vascular occlusion device
US5972009A (en) 1998-04-07 1999-10-26 Boston Scientific Corporation Ligating band with rounded edges and method of use of same
US6009614A (en) 1998-04-21 2000-01-04 Advanced Cardiovascular Systems, Inc. Stent crimping tool and method of use
US6141855A (en) 1998-04-28 2000-11-07 Advanced Cardiovascular Systems, Inc. Stent crimping tool and method of use
US6003517A (en) 1998-04-30 1999-12-21 Ethicon Endo-Surgery, Inc. Method for using an electrosurgical device on lung tissue
US6240615B1 (en) 1998-05-05 2001-06-05 Advanced Cardiovascular Systems, Inc. Method and apparatus for uniformly crimping a stent onto a catheter
US6493589B1 (en) 1998-05-07 2002-12-10 Medtronic, Inc. Methods and apparatus for treatment of pulmonary conditions
US6327505B1 (en) 1998-05-07 2001-12-04 Medtronic, Inc. Method and apparatus for rf intraluminal reduction and occlusion
US6024759A (en) 1998-05-08 2000-02-15 Walter Lorenz Surgical, Inc. Method and apparatus for performing pectus excavatum repair
US6471718B1 (en) 1998-05-15 2002-10-29 American Medical Systems, Inc. Method and device for loading a stent
WO1999059503A8 (en) 1998-05-15 2000-01-20 American Med Syst Method and device for loading a stent
US6132458A (en) 1998-05-15 2000-10-17 American Medical Systems, Inc. Method and device for loading a stent
WO2001054585A1 (en) 1998-06-05 2001-08-02 Broncus Technologies, Inc. Method and assembly for lung volume reduction
US6599311B1 (en) 1998-06-05 2003-07-29 Broncus Technologies, Inc. Method and assembly for lung volume reduction
US6174323B1 (en) 1998-06-05 2001-01-16 Broncus Technologies, Inc. Method and assembly for lung volume reduction
WO1999064109A1 (en) 1998-06-10 1999-12-16 Broncus Technologies, Inc. Smooth muscle treatment apparatus and method
US6086543A (en) 1998-06-24 2000-07-11 Rubicor Medical, Inc. Fine needle and core biopsy devices and methods
US6077214A (en) 1998-07-29 2000-06-20 Myocor, Inc. Stress reduction apparatus and method
US6299604B1 (en) 1998-08-20 2001-10-09 Cook Incorporated Coated implantable medical device
US6241678B1 (en) 1998-08-21 2001-06-05 Aga Medical Corporation Sizing catheter for measuring septal defects
US6210338B1 (en) 1998-08-21 2001-04-03 Aga Medical Corp. Sizing catheter for measuring cardiovascular structures
WO2000012011A1 (en) 1998-08-27 2000-03-09 Shoshan Hendler Apparatus and method for acquisition and retrieval of resected biological specimens
US6149664A (en) 1998-08-27 2000-11-21 Micrus Corporation Shape memory pusher introducer for vasoocclusive devices
US6506166B1 (en) 1998-08-27 2003-01-14 Shoshan Hendler Apparatus and method for acquisition and retrieval of resected biological specimens
US6264700B1 (en) 1998-08-27 2001-07-24 Endonetics, Inc. Prosthetic gastroesophageal valve
US6342062B1 (en) 1998-09-24 2002-01-29 Scimed Life Systems, Inc. Retrieval devices for vena cava filter
US6331183B1 (en) 1998-09-24 2001-12-18 Scimed Life Systems, Inc. Basket filter
WO2000018329A1 (en) 1998-09-30 2000-04-06 Impra, Inc. Apparatus for loading a bag enclosed stent on a catheter
US6096027A (en) 1998-09-30 2000-08-01 Impra, Inc., A Subsidiary Of C.R. Bard, Inc. Bag enclosed stent loading apparatus
US6270527B1 (en) 1998-10-16 2001-08-07 Sulzer Carbomedics Inc. Elastic valve with partially exposed stent
RU2140211C1 (en) 1998-10-28 1999-10-27 Российская медицинская академия последипломного образования Министерства здравоохранения Российской Федерации Method of surgical treatment of patients with pathology of respiratory organs complicated with pulmonary hemorrhages
US20030109869A1 (en) 1998-10-28 2003-06-12 Shadduck John H. Medical instrument working end and method for endoluminal treatments
US6911028B2 (en) 1998-10-28 2005-06-28 John H. Shadduck Medical instrument working end and method for endoluminal treatments
US6454754B1 (en) 1998-10-29 2002-09-24 Steven R. Frank Respiratory infection treatment device
US6020380A (en) 1998-11-25 2000-02-01 Tap Holdings Inc. Method of treating chronic obstructive pulmonary disease
US6051022A (en) 1998-12-30 2000-04-18 St. Jude Medical, Inc. Bileaflet valve having non-parallel pivot axes
WO2000042950A3 (en) 1999-01-26 2000-11-30 Edwards Lifesciences Corp Flexible heart valve
US6439233B1 (en) 1999-02-01 2002-08-27 ADEVA Medical Gesellschaft für Entwicklung und Vertrieb von Medizinischen Implantat-Artikeln mbH Tracheal stoma valve
US6425916B1 (en) 1999-02-10 2002-07-30 Michi E. Garrison Methods and devices for implanting cardiac valves
US6296639B1 (en) 1999-02-12 2001-10-02 Novacept Apparatuses and methods for interstitial tissue removal
US6090041A (en) 1999-02-16 2000-07-18 Regents Of The University Of California vacuum actuated surgical retractor and methods
DE10004979B4 (en) 1999-02-18 2008-04-03 Tokendo (S.A.R.L.) System for inserting endoprostheses
GB2348138B (en) 1999-02-18 2003-05-07 Tokendo Method and apparatus for positioning tracheal/bronchial endoprostheses
WO2000051510A1 (en) 1999-03-01 2000-09-08 Broncus Technologies, Inc. Bronchial stenter having expandable electrodes
US6090035A (en) 1999-03-19 2000-07-18 Isostent, Inc. Stent loading assembly for a self-expanding stent
US6231589B1 (en) 1999-03-22 2001-05-15 Microvena Corporation Body vessel filter
WO2000062699A3 (en) 1999-04-21 2001-04-26 Broncus Tech Inc Modification of airways by application of energy
US6146357A (en) 1999-05-07 2000-11-14 Embol-X, Inc. Balloon occlusion diameter and pressure measuring devices and methods of use
US6206918B1 (en) 1999-05-12 2001-03-27 Sulzer Carbomedics Inc. Heart valve prosthesis having a pivot design for improving flow characteristics
US6241758B1 (en) 1999-05-28 2001-06-05 Advanced Cardiovascular Systems, Inc. Self-expanding stent delivery system and method of use
US6168617B1 (en) 1999-06-14 2001-01-02 Scimed Life Systems, Inc. Stent delivery system
WO2000078407A1 (en) 1999-06-18 2000-12-28 Powerlung Inc Pulmonary exercise device
US6146388A (en) 1999-06-21 2000-11-14 Surgical Concepts, Inc. Rocking apparatus for manipulating element in the eye
WO2000078386A1 (en) 1999-06-23 2000-12-28 Medtronic Percusurge, Inc. Integrated inflation/deflation device and method
US6234996B1 (en) 1999-06-23 2001-05-22 Percusurge, Inc. Integrated inflation/deflation device and method
US6997951B2 (en) 1999-06-30 2006-02-14 Edwards Lifesciences Ag Method and device for treatment of mitral insufficiency
US20040039443A1 (en) 1999-06-30 2004-02-26 Solem Jan Otto Method and device for treatment of mitral insufficiency
WO2001002042A1 (en) 1999-07-02 2001-01-11 Pulmonx Methods, systems, and kits for lung volume reduction
US6287290B1 (en) 1999-07-02 2001-09-11 Pulmonx Methods, systems, and kits for lung volume reduction
CA2375752A1 (en) 1999-07-02 2001-01-11 Pulmonx Methods, systems, and kits for lung volume reduction
EP1198269A1 (en) 1999-07-02 2002-04-24 Pulmonx Methods, systems, and kits for lung volume reduction
US20010056274A1 (en) 1999-07-02 2001-12-27 Perkins Rodney A. Methods, systems, and kits for lung volume reduction
US7141046B2 (en) 1999-07-02 2006-11-28 Pulmonx Methods, systems, and kits for lung volume reduction
US20020062120A1 (en) 1999-07-02 2002-05-23 Pulmonx Methods, systems, and kits for lung volume reduction
US6709401B2 (en) 1999-07-02 2004-03-23 Pulmonx Methods, systems, and kits for lung volume reduction
WO2001003641A1 (en) 1999-07-07 2001-01-18 Astrazeneca Ab Closure device for a medical container
US6241654B1 (en) 1999-07-07 2001-06-05 Acorn Cardiovasculr, Inc. Cardiac reinforcement devices and methods
WO2001003642A1 (en) 1999-07-08 2001-01-18 Broncus Technologies, Inc. Increasing gas exchange of a lung
WO2001005334A1 (en) 1999-07-19 2001-01-25 Sulzer Carbomedics Inc. Heart valve leaflet with reinforced free margin
US6227083B1 (en) 1999-07-30 2001-05-08 Fa-Hsi Tseng Chamfer forming head for paper roll
US6749606B2 (en) 1999-08-05 2004-06-15 Thomas Keast Devices for creating collateral channels
US20020111619A1 (en) 1999-08-05 2002-08-15 Broncus Technologies, Inc. Devices for creating collateral channels
US6629951B2 (en) 1999-08-05 2003-10-07 Broncus Technologies, Inc. Devices for creating collateral in the lungs
US20020087153A1 (en) 1999-08-05 2002-07-04 Broncus Technologies, Inc. Devices for creating collateral channels
WO2001010313A1 (en) 1999-08-05 2001-02-15 Kensey Nash Corporation System and method for delivering agents into targeted tissue of a living being
EP1151729A1 (en) 1999-08-05 2001-11-07 Broncus Technologies, Inc. Methods and devices for creating collateral channels in the lungs
WO2001010314A2 (en) 1999-08-05 2001-02-15 Broncus Technologies, Inc. Methods and devices for creating collateral channels in the lungs
US6712812B2 (en) 1999-08-05 2004-03-30 Broncus Technologies, Inc. Devices for creating collateral channels
US8192478B2 (en) 1999-08-09 2012-06-05 Cardiokinetix, Inc. System for improving cardiac function
WO2001012104A1 (en) 1999-08-13 2001-02-22 Percusurge, Inc. Occlusion of a vessel
US20010051799A1 (en) 1999-08-23 2001-12-13 Ingenito Edward P. Tissue volume reduction
US6682520B2 (en) 1999-08-23 2004-01-27 Bistech, Inc. Tissue volume reduction
US6610043B1 (en) 1999-08-23 2003-08-26 Bistech, Inc. Tissue volume reduction
WO2001013908A9 (en) 1999-08-23 2002-06-27 Edward P Ingenito Tissue volume reduction
EP1206276B1 (en) 1999-08-23 2004-10-20 Edward P. Ingenito Tissue volume reduction
WO2001013839A1 (en) 1999-08-24 2001-03-01 Spiration, Inc. Lung reduction device, system, and method
US6293951B1 (en) 1999-08-24 2001-09-25 Spiration, Inc. Lung reduction device, system, and method
US6416554B1 (en) 1999-08-24 2002-07-09 Spiration, Inc. Lung reduction apparatus and method
EP1078601B1 (en) 1999-08-24 2006-10-04 Spiration, Inc. Kit for lung volume reduction
JP3742010B2 (en) 1999-08-24 2006-02-01 スピレーション インコーポレイテッド Apparatus and system for reducing lung volume
US6258100B1 (en) 1999-08-24 2001-07-10 Spiration, Inc. Method of reducing lung size
WO2001015604A1 (en) 1999-08-31 2001-03-08 The University Of Western Australia Methods and devices for obtaining samples from hollow viscera
US6203551B1 (en) 1999-10-04 2001-03-20 Advanced Cardiovascular Systems, Inc. Chamber for applying therapeutic substances to an implant device
US6280398B1 (en) 1999-10-18 2001-08-28 Ethicon Endo-Surgery Methods and devices for collection of soft tissue
US6569166B2 (en) 1999-10-20 2003-05-27 Spiration, Inc. Method for expanding the thorax
US20010041906A1 (en) 1999-10-20 2001-11-15 Spiration, Inc. Apparatus and method for expanding the thorax
US6402754B1 (en) 1999-10-20 2002-06-11 Spiration, Inc. Apparatus for expanding the thorax
WO2001028433A1 (en) 1999-10-20 2001-04-26 Spiration, Inc. Apparatus and method for expanding the thorax
US20020077593A1 (en) 1999-10-21 2002-06-20 Pulmonx Apparatus and method for isolated lung access
US6398775B1 (en) 1999-10-21 2002-06-04 Pulmonx Apparatus and method for isolated lung access
US6440164B1 (en) 1999-10-21 2002-08-27 Scimed Life Systems, Inc. Implantable prosthetic valve
US6551303B1 (en) 1999-10-27 2003-04-22 Atritech, Inc. Barrier device for ostium of left atrial appendage
WO2001030266A9 (en) 1999-10-27 2002-08-15 Atritech Inc Filter apparatus for ostium of left atrial appendage
WO2001030268A1 (en) 1999-10-27 2001-05-03 Atritech, Inc. Barrier device for ostium of left atrial appendage
WO2001037897A3 (en) 1999-11-29 2002-01-03 Aga Medical Corp Sizing catheter for measuring cardiovascular structures
US6648897B2 (en) 1999-12-07 2003-11-18 Scimed Life Systems, Inc. Flexible vacuum grabber for holding lesions
US20020038125A1 (en) 1999-12-07 2002-03-28 Peter Hamilton Flexible vacuum grabber for holding lesions
US6510846B1 (en) 1999-12-23 2003-01-28 O'rourke Sam Sealed back pressure breathing device
WO2001045590A3 (en) 1999-12-23 2002-03-07 Percusurge Inc Strut design for an occlusion device
US6471979B2 (en) 1999-12-29 2002-10-29 Estrogen Vascular Technology, Llc Apparatus and method for delivering compounds to a living organism
US6458153B1 (en) 1999-12-31 2002-10-01 Abps Venture One, Ltd. Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof
WO2001049213A3 (en) 1999-12-31 2002-01-24 Advanced Bio Prosthetic Surfac Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof
WO2001052775A1 (en) 2000-01-17 2001-07-26 Wittens Cornelis Hendrikus Ann Implant valve for implantation in a blood vessel
US6746686B2 (en) 2000-01-24 2004-06-08 Biocompatibles Uk Limited Coated implants
WO2001054685A1 (en) 2000-01-31 2001-08-02 Genaera Corporation Mucin synthesis inhibitors
WO2001054625A1 (en) 2000-01-31 2001-08-02 Cook Biotech Incorporated Stent valves and uses of same
US6458076B1 (en) 2000-02-01 2002-10-01 5 Star Medical Multi-lumen medical device
US6540782B1 (en) 2000-02-02 2003-04-01 Robert V. Snyders Artificial heart valve
US6600307B2 (en) 2000-03-02 2003-07-29 Sarnoff Corporation Method and apparatus for measuring true transmitted power using a broadband dual directional coupler
CA2401331C (en) 2000-03-04 2010-07-27 Emphasys Medical, Inc. Methods and devices for use in performing pulmonary procedures
US6679264B1 (en) 2000-03-04 2004-01-20 Emphasys Medical, Inc. Methods and devices for use in performing pulmonary procedures
WO2001066190A3 (en) 2000-03-04 2003-08-21 Emphasys Medical Inc Methods and devices for use in performing pulmonary procedures
US6694979B2 (en) 2000-03-04 2004-02-24 Emphasys Medical, Inc. Methods and devices for use in performing pulmonary procedures
US6904909B2 (en) 2000-03-04 2005-06-14 Emphasys Medical, Inc. Methods and devices for use in performing pulmonary procedures
US20010037808A1 (en) 2000-03-04 2001-11-08 Deem Mark E. Methods and devices for use in performing pulmonary procedures
WO2001070114A1 (en) 2000-03-17 2001-09-27 Rita Medical Systems Inc. Lung treatment apparatus
US6328689B1 (en) 2000-03-23 2001-12-11 Spiration, Inc., Lung constriction apparatus and method
US20010025132A1 (en) 2000-03-23 2001-09-27 Spiration, Inc. Tissue resection device, system and method
US6485407B2 (en) 2000-03-23 2002-11-26 Spiration, Inc. Tissue resection device, system and method
WO2001074271A1 (en) 2000-03-31 2001-10-11 Broncus Technologies, Inc. Lung elastic recoil restoring/compression device
US6514290B1 (en) 2000-03-31 2003-02-04 Broncus Technologies, Inc. Lung elastic recoil restoring or tissue compressing device and method
WO2001087170A1 (en) 2000-05-18 2001-11-22 Emphasys Medical, Inc. Bronchiopulmonary occlusion devices and lung volume reduction methods
JP2003533266A (en) 2000-05-18 2003-11-11 エンファシス・メディカル・インコーポレイテッド Broncho-pulmonary closure device and lung volume reduction method
CA2408923A1 (en) 2000-05-18 2001-11-22 David Peter Shaw Bronchiopulmonary occlusion devices and lung volume reduction methods
WO2001089366A2 (en) 2000-05-23 2001-11-29 Broncus Technologies, Inc. Method and assembly for lung volume reduction
WO2001095786A3 (en) 2000-06-16 2002-04-25 Rajiv Doshi Methods and devices for improving breathing in patients with pulmonary disease
US20010052344A1 (en) 2000-06-16 2001-12-20 Rajiv Doshi Methods and devices for improving breathing in patients with pulmonary disease
US20020002401A1 (en) 2000-06-26 2002-01-03 Mcguckin James F. Vascular device for valve leaflet apposition
JP2003503162A5 (en) 2000-06-29 2007-08-09
US6568387B2 (en) 2000-07-19 2003-05-27 University Of Florida Method for treating chronic obstructive pulmonary disorder
US20020007831A1 (en) 2000-07-19 2002-01-24 Davenport Paul W. Method for treating chronic obstructive pulmonary disorder
WO2002005884A8 (en) 2000-07-19 2002-03-28 Univ Florida Method for treating chronic obstructive pulmonary disorder
US6485436B1 (en) 2000-08-10 2002-11-26 Csaba Truckai Pressure-assisted biopsy needle apparatus and technique
US20020147462A1 (en) 2000-09-11 2002-10-10 Closure Medical Corporation Bronchial occlusion method and apparatus
WO2002022072A3 (en) 2000-09-11 2003-08-14 Closure Medical Corp Bronchial occlusion method and apparatus
WO2002022053A3 (en) 2000-09-18 2002-12-27 Endotex Interventional Sys Inc Apparatus for delivering endoluminal prostheses and methods of making and using them
US20020072730A1 (en) 2000-10-12 2002-06-13 Mcgill Scott A. Methods and apparatus for protecting the proximal end of a medical device
US6551255B2 (en) 2000-10-16 2003-04-22 Sanarus Medical, Inc. Device for biopsy of tumors
US7077851B2 (en) 2000-10-17 2006-07-18 Aesculap Ag & Co. Kg Aneurysm clip
US20030199888A1 (en) 2000-10-17 2003-10-23 Aesculap Ag & Co. Kg Aneurysm clip
WO2002032333A1 (en) 2000-10-17 2002-04-25 Broncus Technologies, Inc. Control system and process for application of energy to airway walls and other mediums
WO2002034322B1 (en) 2000-10-26 2003-04-24 Sam O'rourke Sealed back pressure breathing device
WO2002094087A1 (en) 2000-10-27 2002-11-28 Pulmonx Sheath and method for reconfiguring lung viewing scope
WO2002038038A9 (en) 2000-10-27 2003-09-12 Pulmonx Methods and devices for obstructing and aspirating lung tissue segments
AU2002239759A1 (en) 2000-10-27 2002-05-21 Pulmonx Methods and devices for obstructing and aspirating lung tissue segments
US6527761B1 (en) 2000-10-27 2003-03-04 Pulmonx, Inc. Methods and devices for obstructing and aspirating lung tissue segments
US6585639B1 (en) 2000-10-27 2003-07-01 Pulmonx Sheath and method for reconfiguring lung viewing scope
WO2002069808A9 (en) 2000-11-06 2003-12-31 Suros Surgical Systems Inc Biopsy apparatus
US20020091411A1 (en) 2000-12-07 2002-07-11 Saker Mark B. Tissue tract sealing device
US6840952B2 (en) 2000-12-07 2005-01-11 Mark B. Saker Tissue tract sealing device
WO2002047575A3 (en) 2000-12-15 2002-12-12 Angiomed Ag Stent with valve
US6620095B2 (en) 2000-12-22 2003-09-16 Syde A. Taheri Cradle-assisted myocardial repair and treatment
WO2002056794A3 (en) 2001-01-18 2002-11-07 Brigham & Womens Hospital Prosthetic device for respiratory patients
US20050222580A1 (en) 2001-02-09 2005-10-06 Concentric Medical, Inc., A Delaware Corporation Methods and devices for delivering occlusion elements
US7175644B2 (en) 2001-02-14 2007-02-13 Broncus Technologies, Inc. Devices and methods for maintaining collateral channels in tissue
US20020111620A1 (en) 2001-02-14 2002-08-15 Broncus Technologies, Inc. Devices and methods for maintaining collateral channels in tissue
WO2002069823A3 (en) 2001-02-14 2002-11-21 Broncus Tech Inc Devices for creating collateral channels
WO2002064045A1 (en) 2001-02-14 2002-08-22 Broncus Technologies, Inc. Devices for creating collateral channels
WO2002064190B1 (en) 2001-02-14 2002-11-21 Broncus Tech Inc Devices for creating collateral channels
US20020112729A1 (en) 2001-02-21 2002-08-22 Spiration, Inc. Intra-bronchial obstructing device that controls biological interaction with the patient
US6955675B2 (en) 2001-03-01 2005-10-18 Cardiac Pacemakers, Inc. Ablation catheter with transducer for providing one or more of pressure, temperature and fluid flow data for use in controlling ablation therapy
US20020123749A1 (en) 2001-03-01 2002-09-05 Jain Mudit K. Ablation catheter with transducer for providing one or more of pressure, temperature and fluid flow data for use in controlling ablation therapy
US7011094B2 (en) 2001-03-02 2006-03-14 Emphasys Medical, Inc. Bronchial flow control devices and methods of use
US20040060563A1 (en) 2001-03-02 2004-04-01 Alan Rapacki Bronchial flow control devices and methods of use
US20020138135A1 (en) 2001-03-21 2002-09-26 Duerig Thomas W. Stent-based venous valves
US6503272B2 (en) 2001-03-21 2003-01-07 Cordis Corporation Stent-based venous valves
US6638285B2 (en) 2001-04-16 2003-10-28 Shlomo Gabbay Biological tissue strip and system and method to seal tissue
US6958076B2 (en) 2001-04-16 2005-10-25 Biomedical Research Associates Inc. Implantable venous valve
WO2002087447A1 (en) 2001-04-27 2002-11-07 Rex Medical, L.P. Surgical biopsy device
US6669724B2 (en) 2001-06-05 2003-12-30 M.I. Tech Co. Ltd. Medical stent
WO2003003946A1 (en) 2001-07-03 2003-01-16 Boston Scientific Limited Eptfe graft with axial elongation properties
US6860847B2 (en) 2001-07-10 2005-03-01 Spiration, Inc. Constriction device viewable under X ray fluoroscopy
US6491706B1 (en) 2001-07-10 2002-12-10 Spiration, Inc. Constriction device including fixation structure
US20030013935A1 (en) 2001-07-10 2003-01-16 Spiration, Inc. Constriction device viewable under X ray fluoroscopy
US7357795B2 (en) 2001-07-19 2008-04-15 Olympus Corporation Medical device and method of embolizing bronchus or bronchiole
US20030018344A1 (en) 2001-07-19 2003-01-23 Olympus Optical Co., Ltd. Medical device and method of embolizing bronchus or bronchiole
US20030018327A1 (en) 2001-07-20 2003-01-23 Csaba Truckai Systems and techniques for lung volume reduction
JP2004535887A (en) 2001-07-26 2004-12-02 エル. フィリップス、バン Socket insert with bladder system
US20030024527A1 (en) 2001-08-03 2003-02-06 Integrated Vascular Systems, Inc. Lung assist apparatus and methods for use
US6743259B2 (en) 2001-08-03 2004-06-01 Core Medical, Inc. Lung assist apparatus and methods for use
US20050267323A1 (en) 2001-08-22 2005-12-01 Gerald Dorros Apparatus and methods for treating stroke and controlling cerebral flow characteristics
US6589240B2 (en) 2001-08-28 2003-07-08 Rex Medical, L.P. Tissue biopsy apparatus with collapsible cutter
US20050137611A1 (en) 2001-09-04 2005-06-23 Broncus Technologies, Inc. Methods and devices for maintaining surgically created channels in a body organ
US20030051733A1 (en) 2001-09-10 2003-03-20 Pulmonx Method and apparatus for endobronchial diagnosis
US20040206349A1 (en) 2001-09-11 2004-10-21 Alferness Clifton A. Removable lung reduction devices, systems, and methods
US20030050648A1 (en) 2001-09-11 2003-03-13 Spiration, Inc. Removable lung reduction devices, systems, and methods
US20030055331A1 (en) 2001-09-11 2003-03-20 Pulmonx Methods of endobronchial diagnosis using imaging
US20090205667A1 (en) 2001-09-11 2009-08-20 Spiration, Inc. Removable lung reduction devices, systems, and methods
WO2003022124A3 (en) 2001-09-11 2003-08-21 Spiration Inc Removable lung reduction devices, systems, and methods
US6632239B2 (en) 2001-10-02 2003-10-14 Spiration, Inc. Constriction device including reinforced suture holes
US20030070682A1 (en) 2001-10-11 2003-04-17 Wilson Peter M. Bronchial flow control devices and methods of use
WO2003030975A3 (en) 2001-10-11 2003-08-28 Emphasis Medical Inc Bronchial flow control devices and methods of use
US6941950B2 (en) 2001-10-11 2005-09-13 Emphasys Medical, Inc. Bronchial flow control devices and methods of use
US20050166925A1 (en) 2001-10-11 2005-08-04 Emphasys Medical, Inc., A California Corporation Bronchial flow control devices and methods of use
US7854228B2 (en) 2001-10-11 2010-12-21 Pulmonx Corporation Bronchial flow control devices and methods of use
US20050145253A1 (en) 2001-10-11 2005-07-07 Emphasys Medical, Inc., A Delaware Corporation Bronchial flow control devices and methods of use
WO2003047468A1 (en) 2001-10-11 2003-06-12 Percutaneous Valve Technologies Implantable prosthetic valve
US20070185531A1 (en) 2001-10-25 2007-08-09 Spiration, Inc. Apparatus and method for deployment of a bronchial obstruction device
US20030083730A1 (en) 2001-10-25 2003-05-01 Scimed Life Systems, Inc. Loading cartridge for self-expanding stent
WO2003034927A1 (en) 2001-10-25 2003-05-01 Spiration, Inc. Bronchial obstruction device deployment system and method
US6592594B2 (en) 2001-10-25 2003-07-15 Spiration, Inc. Bronchial obstruction device deployment system and method
US20030083671A1 (en) 2001-10-25 2003-05-01 Spiration, Inc. Bronchial obstruction device deployment system and method
US6682250B2 (en) 2001-11-07 2004-01-27 Lockheed Martin Corporation Position-adjustable fastening apparatus and method
WO2003041779A9 (en) 2001-11-14 2004-03-11 Emphasys Medical Inc Active pump bronchial implant and methods of use thereof
US20030127090A1 (en) 2001-11-14 2003-07-10 Emphasys Medical, Inc. Active pump bronchial implant devices and methods of use thereof
US20030158515A1 (en) 2002-02-21 2003-08-21 Spiration, Inc. Device and method for intra-bronchial provision of a therapeutic agent
EP1496790B1 (en) 2002-02-21 2013-06-12 Spiration, Inc. Device for intra-bronchial provision of a therapeutic agent
EP2520321A1 (en) 2002-02-21 2012-11-07 Spiration Inc. Device for intra-bronchial provision of a therapeutic agent
US20030154988A1 (en) 2002-02-21 2003-08-21 Spiration, Inc. Intra-bronchial device that provides a medicant intra-bronchially to the patient
US7278430B2 (en) 2002-03-01 2007-10-09 Arvik Enterprises, Llc Blood vessel occlusion device
US20030167065A1 (en) 2002-03-01 2003-09-04 Arvik Enterprises, Llc Blood vessel occlusion device
US7412977B2 (en) 2002-03-08 2008-08-19 Emphasys Medical, Inc. Methods and devices for inducing collapse in lung regions fed by collateral pathways
US20030228344A1 (en) 2002-03-08 2003-12-11 Fields Antony J. Methods and devices for inducing collapse in lung regions fed by collateral pathways
WO2003078579A3 (en) 2002-03-11 2004-07-15 Aeris Therapeutics Inc Compositions and methods for treating emphysema
US7344553B2 (en) 2002-03-15 2008-03-18 Nmt Medical, Inc. Coupling system useful in placement of implants
JP4387803B2 (en) 2002-03-20 2009-12-24 スピレーション インコーポレイテッド Detachable anchored lung volume reduction device
EP2353557A2 (en) 2002-03-20 2011-08-10 Spiration, Inc. Removable anchored lung volume reduction devices and methods
EP1494632A4 (en) 2002-03-20 2008-04-09 Spiration Inc Removable anchored lung volume reduction devices and methods
US20030181922A1 (en) 2002-03-20 2003-09-25 Spiration, Inc. Removable anchored lung volume reduction devices and methods
WO2003079944A1 (en) 2002-03-20 2003-10-02 Spiration, Inc. Removable anchored lung volume reduction devices and methods
US20030181890A1 (en) 2002-03-22 2003-09-25 Schulze Dale R. Medical device that removably attaches to a bodily organ
WO2003088820A8 (en) 2002-04-19 2004-04-08 Broncus Tech Inc Devices for maintaining surgically created openings
US7207946B2 (en) 2002-05-09 2007-04-24 Spiration, Inc. Automated provision of information related to air evacuation from a chest cavity
US20030212337A1 (en) 2002-05-09 2003-11-13 Spiration, Inc. Automated provision of information related to air evacuation from a chest cavity
WO2003094996A1 (en) 2002-05-09 2003-11-20 Spiration, Inc. Automated provision of information related to air evacuation from a chest cavity
US20070250022A1 (en) 2002-05-09 2007-10-25 Sirokman William A Automated provision of information related to air evacuation from a chest cavity
US20030225445A1 (en) 2002-05-14 2003-12-04 Derus Patricia M. Surgical stent delivery devices and methods
US6852108B2 (en) 2002-05-14 2005-02-08 Spiration, Inc. Apparatus and method for resecting and removing selected body tissue from a site inside a patient
US7842061B2 (en) 2002-05-17 2010-11-30 Spiration, Inc. Methods of achieving lung volume reduction with removable anchored devices
US7875048B2 (en) 2002-05-17 2011-01-25 Spiration, Inc. One-way valve devices for anchored implantation in a lung
US7434578B2 (en) 2002-05-17 2008-10-14 Spiration, Inc. Methods of achieving lung volume reduction with removable anchored devices
US20050033344A1 (en) 2002-05-17 2005-02-10 Dillard David H. One-way valve devices for anchored implantation in a lung
US20040167636A1 (en) 2002-05-17 2004-08-26 Dillard David H. Methods of achieving lung volume reduction with removable anchored devices
US20040143282A1 (en) 2002-05-17 2004-07-22 Dillard David H. Methods of achieving lung volume reduction with removable anchored devices
JP2005527297A (en) 2002-05-23 2005-09-15 オットー ボック ヘルスケアー エルピー Pulsating pressure chamber in the prosthesis
WO2003099164A1 (en) 2002-05-28 2003-12-04 Emphasys Medical, Inc. Implantable bronchial isolation devices and lung treatment methods
US20040039250A1 (en) 2002-05-28 2004-02-26 David Tholfsen Guidewire delivery of implantable bronchial isolation devices in accordance with lung treatment
US20040211434A1 (en) 2002-07-05 2004-10-28 Broncus Technologies, Inc. Extrapleural airway device and method
US7422584B2 (en) 2002-07-05 2008-09-09 Broncus Technologies, Inc. Extrapleural airway device and method
WO2004010845A9 (en) 2002-07-26 2004-09-16 Emphasys Medical Inc Bronchial flow control devices with membrane seal
US20040024356A1 (en) 2002-07-31 2004-02-05 Don Tanaka Long term oxygen therapy system
US7086398B2 (en) 2002-07-31 2006-08-08 Cordis Corporation Long term oxygen therapy system
US7862500B2 (en) 2002-08-01 2011-01-04 Cardiokinetix, Inc. Multiple partitioning devices for heart treatment
US6886558B2 (en) 2002-08-28 2005-05-03 Cordis Corporation Collateral ventilation bypass trap system
US20040040555A1 (en) 2002-08-28 2004-03-04 Don Tanaka Collateral ventilation bypass trap system
US20060155217A1 (en) 2002-09-24 2006-07-13 Devore Lauri J Device and method for measuring the diameter of an air passageway
US7476203B2 (en) 2002-09-24 2009-01-13 Spiration, Inc. Device and method for measuring the diameter of an air passageway
US6849084B2 (en) 2002-12-31 2005-02-01 Intek Technology L.L.C. Stent delivery system
US20040127912A1 (en) 2002-12-31 2004-07-01 Dmitry Rabkin Stent delivery system
US20040143283A1 (en) 2003-01-17 2004-07-22 Mcgill Scott Inflation adaptor and method of use
WO2004080347A3 (en) 2003-03-12 2005-06-09 Spiration Inc Apparatus, method and assembly for delivery of intra-bronchial devices
US20040210248A1 (en) 2003-03-12 2004-10-21 Spiration, Inc. Apparatus, method and assembly for delivery of intra-bronchial devices
US7637934B2 (en) 2003-03-31 2009-12-29 Merit Medical Systems, Inc. Medical appliance optical delivery and deployment apparatus and method
US7100616B2 (en) 2003-04-08 2006-09-05 Spiration, Inc. Bronchoscopic lung volume reduction method
US20130190679A1 (en) 2003-04-08 2013-07-25 Spiration, Inc. Bronchoscopic lung volume reduction method
US20040200484A1 (en) 2003-04-08 2004-10-14 Springmeyer Steven C. Bronchoscopic lung volume reduction method
US20040210306A1 (en) 2003-04-17 2004-10-21 Quijano Rodolfo C. Device for reduction of pressure effects of cardiac tricuspid valve regurgitation
US7530995B2 (en) 2003-04-17 2009-05-12 3F Therapeutics, Inc. Device for reduction of pressure effects of cardiac tricuspid valve regurgitation
US6989027B2 (en) 2003-04-30 2006-01-24 Medtronic Vascular Inc. Percutaneously delivered temporary valve assembly
US7252086B2 (en) 2003-06-03 2007-08-07 Cordis Corporation Lung reduction system
US20040244802A1 (en) 2003-06-03 2004-12-09 Don Tanaka Lung reduction system
US20050137714A1 (en) 2003-08-08 2005-06-23 Gonzalez Hugo X. Bronchoscopic repair of air leaks in a lung
WO2005013835A1 (en) 2003-08-08 2005-02-17 Spiration, Inc. Bronchoscopic repair of air leaks in a lung
US20090182369A1 (en) 2003-08-08 2009-07-16 Spiration, Inc. Bronchoscopic repair of air leaks in a lung
AU2004263132B2 (en) 2003-08-08 2010-07-01 Spiration, Inc. Bronchoscopic repair of air leaks in a lung
US20050080434A1 (en) 2003-10-08 2005-04-14 Cedars-Sinai Medical Center Laparoscopic retractable dissector and suture and needle passer
US20050096721A1 (en) 2003-10-29 2005-05-05 Mangin Stephen P. Apparatus with visual marker for guiding deployment of implantable prosthesis
US7273469B1 (en) 2003-12-31 2007-09-25 Advanced Cardiovascular Systems, Inc. Modified needle catheter for directional orientation delivery
US7704268B2 (en) 2004-05-07 2010-04-27 Nmt Medical, Inc. Closure device with hinges
US20080132989A1 (en) 2004-06-28 2008-06-05 Xtent, Inc. Devices and methods for controlling expandable prostheses during deployment
WO2006034166A2 (en) 2004-09-17 2006-03-30 Cordis Neurovascular, Inc. Thin film metallic devices for plugging aneurysms or vessels
US6951571B1 (en) 2004-09-30 2005-10-04 Rohit Srivastava Valve implanting device
US20060100687A1 (en) 2004-11-10 2006-05-11 Creganna Technologies Limited Elongate tubular member for use in medical device shafts
US7913698B2 (en) 2004-11-16 2011-03-29 Uptake Medical Corp. Device and method for lung treatment
CA2603948C (en) 2005-04-21 2015-01-27 Jan Otto Solem A blood flow controlling apparatus
US20060241745A1 (en) 2005-04-21 2006-10-26 Solem Jan O Blood flow controlling apparatus
WO2006124822A1 (en) 2005-05-13 2006-11-23 Alveolus, Inc. Delivery device allowing visual inspection of an intravascular site
US20060270940A1 (en) 2005-05-25 2006-11-30 Ross Tsukashima Self-condensing pH sensor and catheter apparatus
JP2009503031A (en) 2005-08-02 2009-01-29 シエル・インターナシヨナル・リサーチ・マートスハツペイ・ベー・ヴエー Method for preparing alkylene glycol
US20070225747A1 (en) 2006-03-08 2007-09-27 Pulmonx Methods and devices to induce controlled atelectasis and hypoxic pulmonary vasoconstriction
US20070209204A1 (en) 2006-03-09 2007-09-13 Chase Daniel J Hose Assembly Process, Device, and Product-by-Process
US20070221230A1 (en) 2006-03-13 2007-09-27 David Thompson Minimally invasive lung volume reduction device and method
CN102058443A (en) 2006-03-31 2011-05-18 斯波瑞申有限公司 Articulable anchor
RU2440066C2 (en) 2006-03-31 2012-01-20 Спирэйшн, Инк. Clapper
WO2007123690A2 (en) 2006-03-31 2007-11-01 Spiration, Inc. Articulable anchor
US20070232992A1 (en) 2006-03-31 2007-10-04 James Kutsko Articulable anchor
AU2007241066B2 (en) 2006-03-31 2011-06-09 Spiration, Inc. Articulable anchor
US20100262071A1 (en) 2006-03-31 2010-10-14 James Kutsko Articulable anchor
CN102579155A (en) 2006-03-31 2012-07-18 斯波瑞申有限公司 Articulable anchor
US20080149446A1 (en) 2006-12-22 2008-06-26 Raymond Schuurman Hydraulic clutch circuit
US8711809B2 (en) 2007-04-27 2014-04-29 Blackberry Limited Method and system for efficient DRX operation during handover in LTE
US20090188508A1 (en) 2007-09-14 2009-07-30 Smith Jr A James Disposable medical mouthpiece appliance
US20090292262A1 (en) 2007-10-12 2009-11-26 Martin Neal Adams Valve loader method, system, and apparatus
WO2009049261A1 (en) 2007-10-12 2009-04-16 Spiration, Inc. Valve loader method, system, and apparatus
CN101868199A (en) 2007-10-12 2010-10-20 斯波瑞申有限公司 Valve loader method, system, and apparatus
EP2641572A1 (en) 2007-10-12 2013-09-25 Spiration Inc. Valve loader method, system, and apparatus
JP2011500171A (en) 2007-10-12 2011-01-06 スピレーション インコーポレイテッド Valve loader methods, systems, and apparatus
JP2011523363A (en) 2008-05-01 2011-08-11 スピレーション インコーポレイテッド Direct lung sensor system, method and apparatus
WO2009135070A1 (en) 2008-05-01 2009-11-05 Spiration, Inc. Direct lung sensor systems, methods, and apparatuses
US20100082089A1 (en) 2008-10-01 2010-04-01 Arshad Quadri Delivery system for vascular implant
WO2010118056A1 (en) 2009-04-10 2010-10-14 Spiration, Inc. Valve loader method, system, and apparatus
EP2416737B1 (en) 2009-04-10 2015-03-11 Spiration, Inc. Deployment catheter with marker bands
WO2012158152A1 (en) 2011-05-13 2012-11-22 Spiration, Inc. Deployment catheter
JP2013107784A (en) 2011-11-18 2013-06-06 Shinetsu Quartz Prod Co Ltd Non-doped white fluorescent synthetic silica glass

Non-Patent Citations (31)

* Cited by examiner, † Cited by third party
Title
Amendment mailed Mar. 3, 2004 in response to Office Action dated Oct. 3, 2003 in the related copending U.S. Appl. No. 09/951,105.
Andre A. Kulisz, Autocath 100-Nonsurgical, Intraurethral Bladder Control Device for Urinary Incontinent and Urinary Retentive Women-Another Dr. Kulisz's Development, http://www.kulisz.com/autocath.htm, 2003, 3 pp.
April et al. "Correction of Funnel-Chest According to Senning-Johnson", Schweiz. Rundchau. Med. (PRAXIS) 79, Nr. 12 (1980) pp. 356-360.
Chest Drains, from webmaster@atroi.ed/cp., from website Mar. 21, 2002; pp. 1-3.
Chest Drains, from webmaster@surgical-tutor.org.uk; from Website on Mar. 21, 2002; pp. 1-3.
Dillard et al., "Evaluation of a Novel Intra-bronchial Valve Device to Produce Lung Volume Reduction," Poster shown at conference in Jun. 2002.
EDO Ceramics Products and Services, from webmaster@edocorp.com; from website on Mar. 21, 2002; pp. 1,2.
Ellis, James H., Balloon Catheter Occlusion of Bronchopleural Fistulae, May 7, 1981, AJR: 138, Jan. 1982, p. 157-159.
EWS Endobronchial Watanabe Spigots, Novatech, edited Apr. 17, 2002.
Exploring Chest Drain Options; from webmaster google.com; RNWeb: Continuing Education; from website on Mar. 21, 2002; pp. 1-6.
Harris et al., "The Experimental Production in Dogs of Emphysema with Associated Asthmatic Syndrome by Means of an Intratracheal Ball Valve," J. Exp Med 30:1919; 75-88.
Horiuchi et al: Three Cases of Intractable Pneumothorax Treated Successfully by Bronchial Embolization using Silicon; JJSB, 2001. pp. 25-30.
Inaspettato: Endoscopic Treatment of Bronchopleural Fistulas Using N-butyl-2-cyanoacrylate; Surgical Laparoscopy & Endoscopy; vol. 4 No. 1, pp. 62-64, 1994.
J&J Gateway LLC Web Page: Steps in the Mammotome Surgical Procedure; Surgical Technique, Dec. 28, 2001; p. 1-3.
Jones et al: Closure of a Benign Broncho-Oesophageal Fistula by Endoscopic Injection of Bovine Collagen, Cyanocrylate Glue and Gelfoam; 1996, pp. 53-55 Aust. N.Z. J. Surg.
Lewis et al., "Pulmonary Interstitial Emphysema: Selective Bronchial Occlusion with a Swan-Ganz Catheter." Archives of Disease in Childhood, 63:1988, 313-315.
Marco: Bubble Detector, from webmaster@marco.de, from Website on Mar. 21, 2002; pp. 1-3.
Mathew et al. "Selective Bronchial Obstruction for Treatment of Bullous Interstitial Emphysema," J. of Ped. 96:1980, 475-477.
Oasis Dry Suction Chest Drains; Instructions for Use; Atrium Medical Corporation, Hudson New Hampshire, on Mar. 27, 2002,pp. 1-4.
Ochsner et al. "Chone-Chondrosternon", Journal of Thoracic Surgery, vol. 8, No. 5, Jun. 1939, pp. 469-511.
Okada et al: Emergent Bronchofiberoptic Bronchial Occlusion for Intractable Pneumothorax with Severe Emphysema; The Japanese Journal of Thoracic and Cardiovascular Surgery, 1998. pp. 1078-1081.
Puhakka et al., "Acute Bronchial Obstruction: An Experimental Rabbit Model Study." Int. J. Of Pediatric Otorhinolaryngology. 18:1989, 107-118.
Shamberger, "Congenital Chest Wall Deformities" Current Problems in Surgery vol. XXXIII, No. 6, Jun. 1996, pp. 470-543.
SIII Control and Display Modules; from webmaster@stoeckert.de; from website on Mar. 21, 2002, pp. 15.
Snider et al., "The Definition of Emphysema: Report of the National Heart Lung and Blood Institute, Division of Lung Diseases Workshop", Am. Rev. Respir. Dis., 132:182-185, 1985.
Tanase, D., et al.: "Investigation of Multi-Sensor Techniques for Cardiac-Output Measurements in Intensive Care," Microtechnology in Medicine and Biology, 2005, 3rd IEEE/EMB, Special Topic Conference, pp. 122-125.
Tube Thoracostomy; from webmaster@merck.com/pubs/manual; from Website Mar. 21, 2003, pp. 1,2.
U.S. Appl. No. 13/388,621, filed Mar. 29, 2013, Alferness.
U.S. Appl. No. 13/787,052, filed Mar. 6, 2013, Alferness et al.
Understanding Chest Drainage; from webmaster@nursingceu.com; from website on Mar. 21, 2002; pp. 1-15.
Watanabe et al: Bronchial Embolization Using Dental Impression Material in a Case of Pyelo-bronchial Fistula with Candida Fungemia; 1991. Journal of the Japan Society for Bronchology, pp. 607-610.

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9622752B2 (en) 2003-08-08 2017-04-18 Spiration, Inc. Bronchoscopic repair of air leaks in a lung
US9198669B2 (en) 2006-03-31 2015-12-01 Spiration, Inc. Articulable anchor
US10470839B2 (en) 2016-06-02 2019-11-12 Covidien Lp Assessment of suture or staple line integrity and localization of potential tissue defects along the suture or staple line

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