US3310051A - Surgical reservoir for implantation beneath the skin - Google Patents

Surgical reservoir for implantation beneath the skin Download PDF

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US3310051A
US3310051A US329443A US32944363A US3310051A US 3310051 A US3310051 A US 3310051A US 329443 A US329443 A US 329443A US 32944363 A US32944363 A US 32944363A US 3310051 A US3310051 A US 3310051A
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wall
passage
capsule
skin
tube
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US329443A
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Rudolf R Schulte
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American Hospital Supply Corp
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Rudolf R Schulte
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Assigned to AMERICAN HOSPITAL SUPPLY CORPORATION; A CORP OF IL. reassignment AMERICAN HOSPITAL SUPPLY CORPORATION; A CORP OF IL. ASSIGNMENT OF ASSIGNORS INTEREST. Assignors: AMERICAN HEYER- SCHULTE CORPORATION
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02Access sites
    • A61M39/0208Subcutaneous access sites for injecting or removing fluids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0687Skull, cranium

Definitions

  • This invention relates to a surgical implant which provides a reservoir located conveniently to the skin of a person which may be utilized to introduce, withdraw, or mix fluids in regions located farther inside the body.
  • Still another object of the invention is to provide a mixing or flushing reservoir into which fluids may readily be injected or from which they may readily be withdrawn.
  • An optional object is to provide such a reservoir which may also serve to provide surge-generatiug means of flush and mix fluids in it and in the region under treatment.
  • a device comprises a tube having a central passage, the tube being adapted to be inserted in to the body so that its passage communicates with a selected region therein.
  • a capsule is adapted to be connected to this tube and to be placed beneath the skin of the body.
  • This capsule comprises an enclosure which has an internal periphery and a first and second wall, these walls facing each other inside the capsule. The wall next to the skin is tolerant to, and self-sealing after, needle puncture.
  • One of the walls has a passage therethrough in fluid communication with the passage through the tube.
  • one of the walls is flexible and palpable through the skin by force exerted by the hand.
  • the material of the flexible wall is flexible enough to be moved toward the other wall and thereby reduce the volume of the capsule and also sufficiently springy to return to its normal unstressed condition, thereby providing for pumping means to create bi-directional flow in the passages for mixing purposes.
  • FIG. 1 is a cross-section of a portion of a skull, showing the device of the invention, partly in cutaway crosssection and in its normal, unstressed condition;
  • FIG. 2 is a top view of the invention, partly in cutaway cross-section
  • FIG. 3 is a bottom view of the device taken at line 33 of FIG. 1;
  • FIG. 4 is a fragmentary cross-section of a portion of FIG. 1, showing the device in another of its conditions.
  • FIG. 1 illustrates a skull 10, showing the scalp 11 and the bone 12 of the skull surrounding the brain 13.
  • the drawing of the anotomical portions is simplified because these form no portion of the present invention.
  • the device is installed within a burr hole 14 having an internal wall 15 in the bone of the skull, and is held beneath the skin of the scalp by means of a sutured slit 16.
  • the reservoir elements 20 comprising the invention includes a tube 21 having a central passage 22 and a closed end 23. Perforations 24 through the wall provide for fluid communication between the passage and the outside of the tube.
  • the tube is connected to a capsule 25 by means of a connector 26, which connector is attached to a passage extension 27 which has a passage 28 that enters the capsule itself through one wall thereof.
  • the capsule has a boss 29 which fits within burr hole 14 and provides for lateral restraint of the device. The capsule outward of the boss rests on the skull so as to give longitudinal restraint.
  • the capsule is a continuou enclosure and includes a circumferential periphery defined by circumferential edge 30.
  • First and second interior walls 31, 32 are provided on opposite sides of the periphery.
  • the first wall lies closer to the skull, and includes an interior crown 33 which surrounds the opening 34 of passage 28 into the interior of the capsule.
  • the crown has a plurality of notches 35 formed therein.
  • Second wall 32 is generally domed and has a central section which is thicker than the edges. This wall is flexible and, as best shown in FIG. 4, is adapted to be palpated by finger pressure through the scalp to move it toward the first wall, thereby reducing the volume of the capsule.
  • the crown is provided to hold them apart. However, the notches provide for fluid flow past the crown to the passage even when the second wall is pressed against the crown.
  • the entire structure is, of course, made of material which is compatible with the human tissue with which it comes in contact.
  • a convenient substance is silicone rubber manufactured by Dow Corning Company, of Midland, Mich.
  • the thickness of the second wall is selected such that it is springy enough to restore itself to its normal, unstressed condition shown in FIG. 1, and yet sufliciently flexible that it can be deflected to the configuration shown in FIG. 4. It is also tolerant to repetitive needle punctures (with a resonable number), because, as best shown in FIG. 1, material may be in- 3 jected from a hypodermic syringe 36 by puncturing the scalp and the second wall with the needle. When the needle is withdrawn, the material of the second wall will seal the opening made by the needle.
  • the tube will be forced into this region by means well known in the surgical arts. Once in place, this tube is connected to the capsule, and the capsule is placed in position as shown, and the scalp sutured over the capsule.
  • the capsule is filled with fluid, which, after a time, will be identical with fluid in the region under study, particularly if the device is pumped for a while, either by depressing the second wall or by pumping with a syringe.
  • the fluid may be withdrawn for sampling by a hypodermic syringe.
  • medication may be introduced to the region by a syringe as shown, mixing being attained either by depressing the second wall or by pumping with the syringe.
  • this device provides a reservoir of fluid which in effect is an extension of a region under treatment or study. Only one puncture of the brain or other region is necessary because the tube remains in place for sensible periods of time to provide a continuously-available conduit to the region, and the dome i available for introduction and withdrawal of material even were the second wall to be too stifl to flex. On the other hand, should the device be made flexible enough for this purpose, then even better results may be attained as a result of the more complete bi-directional flow attainable thereby.
  • a reservoir element for implantation in a human being comprising: a tube having a central passage and adapted to be inserted into the body so that its passage communicates with a selected region to be treated; and
  • a capsule of a size to be placed beneath the skin so as to rest between the skin and the bony structure of the body said capsule comprising an envelope having an in ner cavity bounded by a first and a second wall, the first wall being adapted to lay on surface to surface contact with said bony structure, the second wall being domed and springily flexible so as to be deformable and movable toward the first wall so as to reduce the volume of the cavity as the result of external force thereon, and to return to its dome shape of its own accord when the force is removed, there being a passage through said first wall connected to the passage in the tube, and a crown formed inside the cavity around the entrance of the passage thereinto, said cr-own having notches thereon, whereby the walls are prevented from adhering to each other and also from shutting off flow through the passage when the capsule is compressed, the second wall being made of material which permits puncture by a needle and is self-sealing after the needle is withdrawn.
  • a reservoir element according to claim 1 in which a boss surrounds the capsule passage on the outside surface of the first wall, whereby to fit in a hole in the said bony structure and thereby to provide lateral positioning support for the capsule.

Description

arch 21, 1967 R. R. SCHULTE 3,31%051 SURGICAL RESERVOIR FOR IMPLANTATION BENEATH THE SKIN Filed Dec. 10, 1963 SCALP-// rfmaw United States Patent 3,310,051 SURGICAL RESERVGIR FOR Iii PLANTATION BENEATH THE SKIN Rudolf R. Schulte, 3328 Calle Fresno, Santa Barbara, Calif. 93185 Filed Dec. 10, 1963, Ser. No. 329,443 2 Claims. (Cl. 128-216) This invention relates to a surgical implant which provides a reservoir located conveniently to the skin of a person which may be utilized to introduce, withdraw, or mix fluids in regions located farther inside the body.
There are numerous instances Where repetitive samplings of body fluids need to be made, or in which repetitive introductions or medication must be made to interior regions. An example i the repetitive sampling of cerebro-spinal fluid, and vthe introduction of medication thereto, such as in the treatment of cryptococcal meningitis or tubercular meningitis. Medication for these diseases is often only marginally effective if given intravenously, because in order to supply the concentration needed at the situs of the ailment, the total dosage in the body would have to be too high. In fact, these diseases have been unmanageable with intravenous injections principally for this reason. However, if the medications are injected at the situs of the ailment, the local concentration can be made high enough to be effective, and the diseases may be controlled, even though the total dosage in the body is relatively low.
A concurrent problem associated with the foregoing is that concentration levels need to be maintained at the situs over a protracted period of time. To make repeated injections by means of repetitive punctures is obviously undesirable, and in many regions of the body soon becomes impossible. One reason is that fibrosis develops around t-he multiple needle tracks and renders access increasingly diflicult, particularly in the brain. Furthermore, repeated punctures of the brain are inherently undesirable. While the examples given in this specification relate to treatment of regions within the skull, clearly the same criteria apply to ailments in other regions of the body.
It is an object of this invention to provide a device which, once installed, gives continuous access to internal regions of the body without requiring additional needle penetrations into these regions. Instead, a tubular portion of the device remains in the body and extends to the affected area where it serves as a continuously-available conduit placed there but once. Thereafter, a syringe or other device need only be placed in fluid communication with this conduit to inject, Withdraw or mix fluids in the interior region.
Still another object of the invention is to provide a mixing or flushing reservoir into which fluids may readily be injected or from which they may readily be withdrawn. An optional object is to provide such a reservoir which may also serve to provide surge-generatiug means of flush and mix fluids in it and in the region under treatment.
A device according to this invention comprises a tube having a central passage, the tube being adapted to be inserted in to the body so that its passage communicates with a selected region therein. A capsule is adapted to be connected to this tube and to be placed beneath the skin of the body. This capsule comprises an enclosure which has an internal periphery and a first and second wall, these walls facing each other inside the capsule. The wall next to the skin is tolerant to, and self-sealing after, needle puncture. One of the walls has a passage therethrough in fluid communication with the passage through the tube.
According to a preferred but optional feature of the invention, one of the walls is flexible and palpable through the skin by force exerted by the hand. The material of the flexible wall is flexible enough to be moved toward the other wall and thereby reduce the volume of the capsule and also sufficiently springy to return to its normal unstressed condition, thereby providing for pumping means to create bi-directional flow in the passages for mixing purposes.
The above and other features of this invention will be fully understood from the following detailed description and the accompanying drawings in which:
FIG. 1 is a cross-section of a portion of a skull, showing the device of the invention, partly in cutaway crosssection and in its normal, unstressed condition;
FIG. 2 is a top view of the invention, partly in cutaway cross-section;
FIG. 3 is a bottom view of the device taken at line 33 of FIG. 1; and
FIG. 4 is a fragmentary cross-section of a portion of FIG. 1, showing the device in another of its conditions.
FIG. 1 illustrates a skull 10, showing the scalp 11 and the bone 12 of the skull surrounding the brain 13. The drawing of the anotomical portions is simplified because these form no portion of the present invention. It will be noted that the device is installed within a burr hole 14 having an internal wall 15 in the bone of the skull, and is held beneath the skin of the scalp by means of a sutured slit 16.
The reservoir elements 20 comprising the invention includes a tube 21 having a central passage 22 and a closed end 23. Perforations 24 through the wall provide for fluid communication between the passage and the outside of the tube. The tube is connected to a capsule 25 by means of a connector 26, which connector is attached to a passage extension 27 which has a passage 28 that enters the capsule itself through one wall thereof. The capsule has a boss 29 which fits within burr hole 14 and provides for lateral restraint of the device. The capsule outward of the boss rests on the skull so as to give longitudinal restraint.
The capsule is a continuou enclosure and includes a circumferential periphery defined by circumferential edge 30. First and second interior walls 31, 32 are provided on opposite sides of the periphery. The first wall lies closer to the skull, and includes an interior crown 33 which surrounds the opening 34 of passage 28 into the interior of the capsule. The crown has a plurality of notches 35 formed therein.
Second wall 32 is generally domed and has a central section which is thicker than the edges. This wall is flexible and, as best shown in FIG. 4, is adapted to be palpated by finger pressure through the scalp to move it toward the first wall, thereby reducing the volume of the capsule. In order to prevent the first and second walls from adhering to each other and closing the passages, the crown is provided to hold them apart. However, the notches provide for fluid flow past the crown to the passage even when the second wall is pressed against the crown.
The entire structure is, of course, made of material which is compatible with the human tissue with which it comes in contact. A convenient substance is silicone rubber manufactured by Dow Corning Company, of Midland, Mich. The thickness of the second wall is selected such that it is springy enough to restore itself to its normal, unstressed condition shown in FIG. 1, and yet sufliciently flexible that it can be deflected to the configuration shown in FIG. 4. It is also tolerant to repetitive needle punctures (with a resonable number), because, as best shown in FIG. 1, material may be in- 3 jected from a hypodermic syringe 36 by puncturing the scalp and the second wall with the needle. When the needle is withdrawn, the material of the second wall will seal the opening made by the needle.
The use of the device should be evident from the foregoing. If it is desired either to withdraw fluid from region 37 within the brain or to introduce medication thereto, the tube will be forced into this region by means well known in the surgical arts. Once in place, this tube is connected to the capsule, and the capsule is placed in position as shown, and the scalp sutured over the capsule. The capsule is filled with fluid, which, after a time, will be identical with fluid in the region under study, particularly if the device is pumped for a while, either by depressing the second wall or by pumping with a syringe. The fluid may be withdrawn for sampling by a hypodermic syringe. Also, medication may be introduced to the region by a syringe as shown, mixing being attained either by depressing the second wall or by pumping with the syringe.
It will thereby be seen that this device provides a reservoir of fluid which in effect is an extension of a region under treatment or study. Only one puncture of the brain or other region is necessary because the tube remains in place for sensible periods of time to provide a continuously-available conduit to the region, and the dome i available for introduction and withdrawal of material even were the second wall to be too stifl to flex. On the other hand, should the device be made flexible enough for this purpose, then even better results may be attained as a result of the more complete bi-directional flow attainable thereby.
This invention is not to be limited by the embodiment shown in the drawings and described in the description which is given by way of example and not of limitation, but only in accordance with the scope of the appended claims.
I claim:
1. A reservoir element for implantation in a human being comprising: a tube having a central passage and adapted to be inserted into the body so that its passage communicates with a selected region to be treated; and
a capsule of a size to be placed beneath the skin so as to rest between the skin and the bony structure of the body, said capsule comprising an envelope having an in ner cavity bounded by a first and a second wall, the first wall being adapted to lay on surface to surface contact with said bony structure, the second wall being domed and springily flexible so as to be deformable and movable toward the first wall so as to reduce the volume of the cavity as the result of external force thereon, and to return to its dome shape of its own accord when the force is removed, there being a passage through said first wall connected to the passage in the tube, and a crown formed inside the cavity around the entrance of the passage thereinto, said cr-own having notches thereon, whereby the walls are prevented from adhering to each other and also from shutting off flow through the passage when the capsule is compressed, the second wall being made of material which permits puncture by a needle and is self-sealing after the needle is withdrawn.
2. A reservoir element according to claim 1 in which a boss surrounds the capsule passage on the outside surface of the first wall, whereby to fit in a hole in the said bony structure and thereby to provide lateral positioning support for the capsule.
References Cited by the Examiner UNITED STATES PATENTS 513,238 1/1894 Lalonde 128-126 3,021,842 2/1962 Flood 128215 3,111,125 11/1963 Schulte 128350 3,144,866 8/1964 Ellis 128232 3,154,074 10/1964 Harrison l28232 FOREIGN PATENTS 790,220 2/ 1958 Great Britain.
OTHER REFERENCES Lancet, vol 2 (63), No. 7315, Nov. 9, 1963, pp. 983-84.
RICHARD A. GAUDET, Primary Examiner.
DALTON L, TRULUCK, Examiner.

Claims (1)

1. A RESERVOIR ELEMENT FOR IMPLANTATION IN A HUMAN BEING COMPRISING: A TUBE HAVING A CENTRAL PASSAGE AND ADAPTED TO BE INSERTED INTO THE BODY SO THAT ITS PASSAGE COMMUNICATES WITH A SELECTED REGION TO BE TREATED; AND A CAPSULE OF A SIZE TO BE PLACED BENEATH THE SKIN SO AS TO REST BETWEEN THE SKIN AND THE BONY STRUCTURE OF THE BODY, SAID CAPSULE COMPRISING AN ENVELOPE HAVING AN INNER CAVITY BOUNDED BY A FIRST AND A SECOND WALL, THE FIRST WALL BEING ADAPTED TO LAY ON SURFACE TO SURFACE CONTACT WITH SAID BONY STRUCTURE, THE SECOND WALL BEING DOMED AND SPRINGILY FLEXIBLE SO AS TO BE DEFORMABLE AND MOVABLE TOWARD THE FIRST WALL SO AS TO BE DEFORMABLE AND OF THE CAVITY AS THE RESULT OF EXTERNAL FORCE THEREON, AND TO RETURN TO ITS DOME SHAPE OF ITS OWN ACCORD WHEN THE FORCE IS REMOVED, THERE BEING A PASSAGE THROUGH SAID FIRST WALL CONNECTED TO THE PASSAGE IN THE TUBE, AND A CROWN FORMED INSIDE THE CAVITY AROUND THE ENTRANCE OF THE PASSAGE THEREINTO, SAID CROWN HAVING NOTCHES THEREON, WHEREBY THE WALLS ARE PREVENTED FROM ADHERING TO EACH OTHER AND ALSO FROM SHUTTING OFF FLOW THROUGH THE PASSAGE WHEN THE CAPSULE IS COMPRESSED, THE SECOND WALL BEING MADE OF MATERIAL WHICH PERMITS PUNCTURE BY A NEEDLE AND IS SELF-SEALING AFTER THE NEEDLE IS WITHDRAWN.
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Cited By (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3530492A (en) * 1967-12-05 1970-09-22 Jack R Ferber Method and apparatus for administering hypodermic injections
US3613663A (en) * 1968-09-09 1971-10-19 Roger P Johnson Apparatus to provide communication with the veins of a patient
DE2124062A1 (en) * 1970-05-18 1971-12-23 The Regents of the University of Minnesota, Minneapolis, Minn. (V.StA.) Implantable infusion pump
US3640269A (en) * 1969-10-24 1972-02-08 Jose M R Delgado Fluid-conducting instrument insertable in living organisms
FR2135326A1 (en) * 1971-05-06 1972-12-15 Gulf Oil Corp
US3731681A (en) * 1970-05-18 1973-05-08 Univ Minnesota Implantable indusion pump
US3765414A (en) * 1972-03-10 1973-10-16 Hydro Med Sciences Inc Drug release system
US3796217A (en) * 1972-03-10 1974-03-12 Hydr Med Sciences Inc Drug release system
US3831583A (en) * 1971-03-05 1974-08-27 Univ California Implantable bulb for inflation of surgical implements
US3864874A (en) * 1973-01-29 1975-02-11 Dale M Norris Method and apparatus for introducing a fluid into the vascular system of a tree or similar plant
US3958562A (en) * 1974-05-30 1976-05-25 Hakim Company Limited Implantable pressure sensor
US3971376A (en) * 1973-02-26 1976-07-27 Ceskoslovenska Akademie Ved Method and apparatus for introducing fluids into the body
US3998222A (en) * 1974-04-15 1976-12-21 Shihata Alfred A Subcutaneous arterio-venous shunt with valve
US4013074A (en) * 1974-06-21 1977-03-22 Siposs George G Implantable medication-dispensing device
US4026287A (en) * 1975-12-10 1977-05-31 Irene Haller Syringe with retractable cannula
DE2724231A1 (en) * 1977-05-25 1978-11-30 Affeld Klaus Collecting container for spermatozoa - includes suture ring implanted over epididymis and tube leading to tap capsule
US4160454A (en) * 1975-07-09 1979-07-10 University Of Utah Implantable catheter system
US4184497A (en) * 1977-08-26 1980-01-22 University Of Utah Peritoneal dialysis catheter
US4190057A (en) * 1977-12-27 1980-02-26 Thoratec Laboratories Corporation Device for determining the patentcy of a blood vessel
US4253201A (en) * 1979-05-24 1981-03-03 Ross David A Prosthesis with self-sealing valve
US4317452A (en) * 1980-02-04 1982-03-02 C. R. Bard, Inc. Body fluid drain
US4405305A (en) * 1980-10-27 1983-09-20 University Of Utah Research Foundation Subcutaneous peritoneal injection catheter
US4464178A (en) * 1981-11-25 1984-08-07 Dalton Michael J Method and apparatus for administration of fluids
FR2551348A1 (en) * 1983-09-02 1985-03-08 Meriaux Henri INFUSION DEVICE
EP0134340A1 (en) * 1983-08-22 1985-03-20 The University of Utah Research Foundation Peritoneal injection catheter apparatus
US4557724A (en) * 1981-02-17 1985-12-10 University Of Utah Research Foundation Apparatus and methods for minimizing cellular adhesion on peritoneal injection catheters
US4559033A (en) * 1980-10-27 1985-12-17 University Of Utah Research Foundation Apparatus and methods for minimizing peritoneal injection catheter obstruction
US4569675A (en) * 1983-09-12 1986-02-11 Infusaid Corporation Transcutaneous infusion system
US4585010A (en) * 1984-07-02 1986-04-29 Enrico Ascer Process and apparatus for measurement of outflow resistance
US4634424A (en) * 1984-04-23 1987-01-06 Windsor Medical, Inc. Multiple re-entry implantable septum and method of using same
US4673394A (en) * 1986-01-17 1987-06-16 Strato Medical Corporation Implantable treatment reservoir
US4687001A (en) * 1977-02-14 1987-08-18 The United States Of America As Represented By The Department Of Health And Human Services Subcutaneous fluid and culture chamber and implant technique
US4710177A (en) * 1986-05-15 1987-12-01 Smith Robert R Subcutaneous ventricular injection apparatus and method
US4710167A (en) * 1985-05-21 1987-12-01 Applied Precision Limited Implantable device for chronically injecting a substance, in particular a therapeutant
US4710174A (en) * 1985-12-16 1987-12-01 Surgical Engineering Associates, Inc. Implantable infusion port
US4767410A (en) * 1985-12-16 1988-08-30 Surgical Engineering Associates, Inc. Implantable infusion port
US4772261A (en) * 1987-01-29 1988-09-20 Board Of Regents, The University Of Texas System Intramedullary catheter
US4772270A (en) * 1987-06-18 1988-09-20 Catheter Technology Corp. Inseparable port/catheter tube assembly and methods
US4772276A (en) * 1987-06-18 1988-09-20 Catheter Technology Corp. Catheter tube coupling assembly and methods
US4781695A (en) * 1986-07-11 1988-11-01 Dalton Michael J Implantable fluid dispenser
EP0309092A1 (en) * 1987-08-25 1989-03-29 Infusaid, Inc. Implantable device
US4857053A (en) * 1988-08-29 1989-08-15 Dalton Michael J Matrix septum
US4904241A (en) * 1986-10-16 1990-02-27 Medical Engineering Corp. Septum with a needle stop at the fluid transfer port
US4915690A (en) * 1988-02-02 1990-04-10 C. R. Bard, Inc. Micro-injection port
US4969870A (en) * 1989-06-07 1990-11-13 The Regents Of The University Of California Method and apparatus for intraosseous infusions
US5041098A (en) * 1989-05-19 1991-08-20 Strato Medical Corporation Vascular access system for extracorporeal treatment of blood
US5092849A (en) * 1987-08-25 1992-03-03 Shiley Infusaid, Inc. Implantable device
US5122114A (en) * 1991-02-01 1992-06-16 Board Of Regents, University Of Texas System Method of using intramedullary catheter
US5312364A (en) * 1993-08-06 1994-05-17 Pyng Intraosseous infusion device
US5332398A (en) * 1992-02-01 1994-07-26 Board Of Regents, The University Of Texas System Intramedullary catheter
US5399168A (en) * 1991-08-29 1995-03-21 C. R. Bard, Inc. Implantable plural fluid cavity port
WO1996014834A1 (en) * 1994-11-10 1996-05-23 University Of Kentucky Research Foundation Implantable refillable controlled release device to deliver drugs directly to an internal portion of the body
US5702414A (en) * 1995-05-14 1997-12-30 Optonol Ltd Method of implanting an intraocular implant
US5713858A (en) * 1995-04-28 1998-02-03 Medtronic, Inc. Permanently implantable guiding catheter
US5792104A (en) * 1996-12-10 1998-08-11 Medtronic, Inc. Dual-reservoir vascular access port
US5817052A (en) * 1995-12-26 1998-10-06 Pyng Medical Corp. Apparatus for intraosseous infusion or aspiration
US5848989A (en) * 1997-06-05 1998-12-15 Davinci Biomedical Research Products, Inc. Implantable port with low profile housing for delivery/collection of fluids and implantation method
US5968058A (en) * 1996-03-27 1999-10-19 Optonol Ltd. Device for and method of implanting an intraocular implant
US6036721A (en) * 1996-11-16 2000-03-14 Cap Incorporated Puncture closure
US6203513B1 (en) 1997-11-20 2001-03-20 Optonol Ltd. Flow regulating implant, method of manufacture, and delivery device
US6478783B1 (en) 2000-05-26 2002-11-12 H. Robert Moorehead Anti-sludge medication ports and related methods
US6558342B1 (en) 1999-06-02 2003-05-06 Optonol Ltd. Flow control device, introducer and method of implanting
US6623462B2 (en) 2001-05-11 2003-09-23 Harmac Medical Products, Inc. Needle safety guard
US6726678B1 (en) * 2001-02-22 2004-04-27 Isurgical, Llc Implantable reservoir and system for delivery of a therapeutic agent
US6736797B1 (en) 1998-06-19 2004-05-18 Unomedical A/S Subcutaneous infusion set
EP1426074A1 (en) * 1995-04-28 2004-06-09 Medtronic Inc. Securing device for intracranial infusion port with filter and catheter
US20040176814A1 (en) * 2002-12-09 2004-09-09 Ruchika Singhal Overmold for a modular implantable medical device
US6824530B2 (en) 2001-05-11 2004-11-30 Harmac Medical Products, Inc. Combination needle assembly and needle safety guard
US20050004618A1 (en) * 2003-05-16 2005-01-06 Scott Erik R. Implantable medical device with a nonhermetic battery
US20050003268A1 (en) * 2003-05-16 2005-01-06 Scott Erik R. Battery housing configuration
US20050004620A1 (en) * 2002-12-09 2005-01-06 Medtronic, Inc. Implantable medical device with anti-infection agent
US20050004637A1 (en) * 2003-05-16 2005-01-06 Ruchika Singhal Explantation of implantable medical device
US20050004619A1 (en) * 2003-05-16 2005-01-06 Wahlstrand Carl D. Headset recharger for cranially implantable medical devices
US20050240155A1 (en) * 2004-04-27 2005-10-27 Conlon Sean P Surgically implantable injection port having a centered catheter connection tube
US20050240156A1 (en) * 2004-04-27 2005-10-27 Conlon Sean P Method of implanting a fluid injection port
US20050245984A1 (en) * 2004-04-30 2005-11-03 Medtronic, Inc. Implantable medical device with lubricious material
US20050245806A1 (en) * 2004-04-29 2005-11-03 Ruchika Singhal Implantation of implantable medical device
US20050288617A1 (en) * 2004-06-25 2005-12-29 Ira Yaron Flow regulating implants
US20070255338A1 (en) * 2006-04-28 2007-11-01 Medtronic, Inc. Cranial implant
US20080195160A1 (en) * 2007-02-08 2008-08-14 Wingeier Brett M Refillable reservoir lead systems
US20080195227A1 (en) * 2007-02-08 2008-08-14 Boling C Lance Drug eluting lead systems
US20090204158A1 (en) * 2003-07-15 2009-08-13 Spinal Generations, Llc Method and device for delivering medicine to bone
US20090204053A1 (en) * 2008-02-11 2009-08-13 Optonol Ltd. Devices and methods for opening fluid passageways
US20090281623A1 (en) * 2008-05-12 2009-11-12 Medtronic, Inc. Customization of implantable medical devices
US20100130943A1 (en) * 2005-05-06 2010-05-27 Medtronic Minimed, Inc. Infusion device and method with disposable portion
US20100262089A1 (en) * 2003-07-15 2010-10-14 Spinal Generations, Llc Method and device for delivering medicine to bone
US20100274259A1 (en) * 1997-11-20 2010-10-28 Optonol Ltd. Fluid drainage device, delivery device, and associated methods of use and manufacture
US8152792B1 (en) * 2008-09-08 2012-04-10 Kornel Ezriel E Subcutaneous drain for a body cavity
US20120232501A1 (en) * 2004-07-13 2012-09-13 Std Med, Inc. Volume Reducing Reservoir Insert for an Infusion Port
US8870836B2 (en) 2003-07-15 2014-10-28 Spinal Generations, Llc Method and device for delivering medicine to bone
US9393432B2 (en) 2008-10-31 2016-07-19 Medtronic, Inc. Non-hermetic direct current interconnect
US9603644B2 (en) 2012-08-07 2017-03-28 Spinal Generations, Llc Methods and devices for delivery of medicine to bone
US9615863B2 (en) 2014-10-22 2017-04-11 Spinal Generations, Llc Multichannel cannula for kyphoplasty and method of use
US20190054284A1 (en) * 2005-12-23 2019-02-21 Angiodynamics, Inc. Implantable Access Port
US10653470B2 (en) 2014-02-19 2020-05-19 Spinal Generation, LLC Compressible mixing and delivery system for medical substances
US11045632B2 (en) 2017-04-24 2021-06-29 Longeviti Neuro Solutions Llc Cerebral spinal fluid shunt plug
US11439798B2 (en) 2017-04-24 2022-09-13 Longeviti Neuro Solutions Llc Cerebral spinal fluid shunt plug

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US513238A (en) * 1894-01-23 Joseph lalonde
GB790220A (en) * 1954-09-14 1958-02-05 Adolfo Scholcoff Elinger Hypodermic syringe ampulla
US3021842A (en) * 1958-11-05 1962-02-20 John F Flood Hypodermic needle guide
US3111125A (en) * 1961-11-06 1963-11-19 Rudolf R Schulte Drainage device
US3144866A (en) * 1961-08-11 1964-08-18 Briggs Castling & Kelly Disposable douche syringe and bag
US3154074A (en) * 1962-10-23 1964-10-27 Lehn & Fink Products Corp Internal medicament applicator

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US513238A (en) * 1894-01-23 Joseph lalonde
GB790220A (en) * 1954-09-14 1958-02-05 Adolfo Scholcoff Elinger Hypodermic syringe ampulla
US3021842A (en) * 1958-11-05 1962-02-20 John F Flood Hypodermic needle guide
US3144866A (en) * 1961-08-11 1964-08-18 Briggs Castling & Kelly Disposable douche syringe and bag
US3111125A (en) * 1961-11-06 1963-11-19 Rudolf R Schulte Drainage device
US3154074A (en) * 1962-10-23 1964-10-27 Lehn & Fink Products Corp Internal medicament applicator

Cited By (160)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3530492A (en) * 1967-12-05 1970-09-22 Jack R Ferber Method and apparatus for administering hypodermic injections
US3613663A (en) * 1968-09-09 1971-10-19 Roger P Johnson Apparatus to provide communication with the veins of a patient
US3640269A (en) * 1969-10-24 1972-02-08 Jose M R Delgado Fluid-conducting instrument insertable in living organisms
DE2124062A1 (en) * 1970-05-18 1971-12-23 The Regents of the University of Minnesota, Minneapolis, Minn. (V.StA.) Implantable infusion pump
US3731681A (en) * 1970-05-18 1973-05-08 Univ Minnesota Implantable indusion pump
US3831583A (en) * 1971-03-05 1974-08-27 Univ California Implantable bulb for inflation of surgical implements
FR2135326A1 (en) * 1971-05-06 1972-12-15 Gulf Oil Corp
US3783868A (en) * 1971-05-06 1974-01-08 Gulf Oil Corp Percutaneous implant
US3796217A (en) * 1972-03-10 1974-03-12 Hydr Med Sciences Inc Drug release system
US3765414A (en) * 1972-03-10 1973-10-16 Hydro Med Sciences Inc Drug release system
US3864874A (en) * 1973-01-29 1975-02-11 Dale M Norris Method and apparatus for introducing a fluid into the vascular system of a tree or similar plant
US3971376A (en) * 1973-02-26 1976-07-27 Ceskoslovenska Akademie Ved Method and apparatus for introducing fluids into the body
US3998222A (en) * 1974-04-15 1976-12-21 Shihata Alfred A Subcutaneous arterio-venous shunt with valve
US3958562A (en) * 1974-05-30 1976-05-25 Hakim Company Limited Implantable pressure sensor
US4013074A (en) * 1974-06-21 1977-03-22 Siposs George G Implantable medication-dispensing device
US4160454A (en) * 1975-07-09 1979-07-10 University Of Utah Implantable catheter system
US4026287A (en) * 1975-12-10 1977-05-31 Irene Haller Syringe with retractable cannula
US4687001A (en) * 1977-02-14 1987-08-18 The United States Of America As Represented By The Department Of Health And Human Services Subcutaneous fluid and culture chamber and implant technique
DE2724231A1 (en) * 1977-05-25 1978-11-30 Affeld Klaus Collecting container for spermatozoa - includes suture ring implanted over epididymis and tube leading to tap capsule
US4184497A (en) * 1977-08-26 1980-01-22 University Of Utah Peritoneal dialysis catheter
US4190057A (en) * 1977-12-27 1980-02-26 Thoratec Laboratories Corporation Device for determining the patentcy of a blood vessel
US4253201A (en) * 1979-05-24 1981-03-03 Ross David A Prosthesis with self-sealing valve
US4317452A (en) * 1980-02-04 1982-03-02 C. R. Bard, Inc. Body fluid drain
US4405305A (en) * 1980-10-27 1983-09-20 University Of Utah Research Foundation Subcutaneous peritoneal injection catheter
US4559033A (en) * 1980-10-27 1985-12-17 University Of Utah Research Foundation Apparatus and methods for minimizing peritoneal injection catheter obstruction
US4557724A (en) * 1981-02-17 1985-12-10 University Of Utah Research Foundation Apparatus and methods for minimizing cellular adhesion on peritoneal injection catheters
US4464178A (en) * 1981-11-25 1984-08-07 Dalton Michael J Method and apparatus for administration of fluids
EP0134340A1 (en) * 1983-08-22 1985-03-20 The University of Utah Research Foundation Peritoneal injection catheter apparatus
EP0134745A1 (en) * 1983-09-02 1985-03-20 Henri Meriaux Infusion device
FR2551348A1 (en) * 1983-09-02 1985-03-08 Meriaux Henri INFUSION DEVICE
US4569675A (en) * 1983-09-12 1986-02-11 Infusaid Corporation Transcutaneous infusion system
US4634424A (en) * 1984-04-23 1987-01-06 Windsor Medical, Inc. Multiple re-entry implantable septum and method of using same
US4585010A (en) * 1984-07-02 1986-04-29 Enrico Ascer Process and apparatus for measurement of outflow resistance
US4710167A (en) * 1985-05-21 1987-12-01 Applied Precision Limited Implantable device for chronically injecting a substance, in particular a therapeutant
US4710174A (en) * 1985-12-16 1987-12-01 Surgical Engineering Associates, Inc. Implantable infusion port
US4767410A (en) * 1985-12-16 1988-08-30 Surgical Engineering Associates, Inc. Implantable infusion port
US4673394A (en) * 1986-01-17 1987-06-16 Strato Medical Corporation Implantable treatment reservoir
US4710177A (en) * 1986-05-15 1987-12-01 Smith Robert R Subcutaneous ventricular injection apparatus and method
US4781695A (en) * 1986-07-11 1988-11-01 Dalton Michael J Implantable fluid dispenser
US4904241A (en) * 1986-10-16 1990-02-27 Medical Engineering Corp. Septum with a needle stop at the fluid transfer port
US4772261A (en) * 1987-01-29 1988-09-20 Board Of Regents, The University Of Texas System Intramedullary catheter
US4772270A (en) * 1987-06-18 1988-09-20 Catheter Technology Corp. Inseparable port/catheter tube assembly and methods
US4772276A (en) * 1987-06-18 1988-09-20 Catheter Technology Corp. Catheter tube coupling assembly and methods
US5092849A (en) * 1987-08-25 1992-03-03 Shiley Infusaid, Inc. Implantable device
EP0309092A1 (en) * 1987-08-25 1989-03-29 Infusaid, Inc. Implantable device
US4915690A (en) * 1988-02-02 1990-04-10 C. R. Bard, Inc. Micro-injection port
US4857053A (en) * 1988-08-29 1989-08-15 Dalton Michael J Matrix septum
US5041098A (en) * 1989-05-19 1991-08-20 Strato Medical Corporation Vascular access system for extracorporeal treatment of blood
US4969870A (en) * 1989-06-07 1990-11-13 The Regents Of The University Of California Method and apparatus for intraosseous infusions
WO1990014857A1 (en) * 1989-06-07 1990-12-13 The Regents Of The University Of California Method and apparatus for intraosseous infusions and aspirations
AU647399B2 (en) * 1989-06-07 1994-03-24 Regents Of The University Of California, The Method and apparatus for intraosseous infusions and aspirations
US5122114A (en) * 1991-02-01 1992-06-16 Board Of Regents, University Of Texas System Method of using intramedullary catheter
US5399168A (en) * 1991-08-29 1995-03-21 C. R. Bard, Inc. Implantable plural fluid cavity port
US6228088B1 (en) 1992-02-01 2001-05-08 Board Of Regents, The University Of Texas System Combination drill bit and intrametullary catheter and method of using same
US5332398A (en) * 1992-02-01 1994-07-26 Board Of Regents, The University Of Texas System Intramedullary catheter
US5312364A (en) * 1993-08-06 1994-05-17 Pyng Intraosseous infusion device
WO1996014834A1 (en) * 1994-11-10 1996-05-23 University Of Kentucky Research Foundation Implantable refillable controlled release device to deliver drugs directly to an internal portion of the body
US5836935A (en) * 1994-11-10 1998-11-17 Ashton; Paul Implantable refillable controlled release device to deliver drugs directly to an internal portion of the body
US5713858A (en) * 1995-04-28 1998-02-03 Medtronic, Inc. Permanently implantable guiding catheter
EP0822844B1 (en) * 1995-04-28 2004-06-30 Medtronic, Inc. Securing device for intercranial infusion port with filter and catheter
EP1426074A1 (en) * 1995-04-28 2004-06-09 Medtronic Inc. Securing device for intracranial infusion port with filter and catheter
US5702414A (en) * 1995-05-14 1997-12-30 Optonol Ltd Method of implanting an intraocular implant
US20040088048A1 (en) * 1995-05-14 2004-05-06 Jacob Richter Intraocular implant, delivery device, and method of implantation
US7481816B2 (en) 1995-05-14 2009-01-27 Optonol Ltd. Intraocular implant, delivery device, and method of implantation
US6468283B1 (en) 1995-05-14 2002-10-22 Optonol, Ltd. Method of regulating pressure with an intraocular implant
US5817052A (en) * 1995-12-26 1998-10-06 Pyng Medical Corp. Apparatus for intraosseous infusion or aspiration
US5968058A (en) * 1996-03-27 1999-10-19 Optonol Ltd. Device for and method of implanting an intraocular implant
US6036721A (en) * 1996-11-16 2000-03-14 Cap Incorporated Puncture closure
US5792104A (en) * 1996-12-10 1998-08-11 Medtronic, Inc. Dual-reservoir vascular access port
US5848989A (en) * 1997-06-05 1998-12-15 Davinci Biomedical Research Products, Inc. Implantable port with low profile housing for delivery/collection of fluids and implantation method
US6510600B2 (en) 1997-11-20 2003-01-28 Optonol, Ltd. Method for manufacturing a flow regulating implant
US8486086B2 (en) 1997-11-20 2013-07-16 Optonol, Ltd Flow regulating implant, method of manufacture, and delivery device
US20080125691A1 (en) * 1997-11-20 2008-05-29 Optonol Ltd. Flow regulating implants
US6203513B1 (en) 1997-11-20 2001-03-20 Optonol Ltd. Flow regulating implant, method of manufacture, and delivery device
US7670310B2 (en) 1997-11-20 2010-03-02 Optonol Ltd Flow regulating implants
US20100274259A1 (en) * 1997-11-20 2010-10-28 Optonol Ltd. Fluid drainage device, delivery device, and associated methods of use and manufacture
US20030079329A1 (en) * 1997-11-20 2003-05-01 Ira Yaron Flow regulating implant, method of manufacture, and delivery device
US8313454B2 (en) 1997-11-20 2012-11-20 Optonol Ltd. Fluid drainage device, delivery device, and associated methods of use and manufacture
US6736797B1 (en) 1998-06-19 2004-05-18 Unomedical A/S Subcutaneous infusion set
US6558342B1 (en) 1999-06-02 2003-05-06 Optonol Ltd. Flow control device, introducer and method of implanting
US6726664B2 (en) 1999-06-02 2004-04-27 Optonol Ltd. Flow control device, introducer and method of implanting
US6478783B1 (en) 2000-05-26 2002-11-12 H. Robert Moorehead Anti-sludge medication ports and related methods
US7063691B2 (en) 2001-02-22 2006-06-20 Regents Of The University Of Minnesota Implantable reservoir and system for delivery of a therapeutic agent
US20040176750A1 (en) * 2001-02-22 2004-09-09 Isurgical, Llc And Regents Of The University Of Minnesota Implantable reservoir and system for delivery of a therapeutic agent
US6726678B1 (en) * 2001-02-22 2004-04-27 Isurgical, Llc Implantable reservoir and system for delivery of a therapeutic agent
US20060253106A1 (en) * 2001-02-22 2006-11-09 Regents Of The University Of Minnesota, Isurgical, Llc Implantable reservoir and system for delivery of a therapeutic agent
US6824530B2 (en) 2001-05-11 2004-11-30 Harmac Medical Products, Inc. Combination needle assembly and needle safety guard
US6623462B2 (en) 2001-05-11 2003-09-23 Harmac Medical Products, Inc. Needle safety guard
US20040176814A1 (en) * 2002-12-09 2004-09-09 Ruchika Singhal Overmold for a modular implantable medical device
US20050004620A1 (en) * 2002-12-09 2005-01-06 Medtronic, Inc. Implantable medical device with anti-infection agent
US7596408B2 (en) 2002-12-09 2009-09-29 Medtronic, Inc. Implantable medical device with anti-infection agent
US8086313B2 (en) 2002-12-09 2011-12-27 Medtronic, Inc. Implantable medical device with anti-infection agent
US20090292327A1 (en) * 2002-12-09 2009-11-26 Medtronic, Inc. Implantable medical device with anti-infection agent
US20070185539A1 (en) * 2002-12-09 2007-08-09 Medtronic, Inc. Overmold for a modular implantable medical device
US7242982B2 (en) 2002-12-09 2007-07-10 Medtronic, Inc. Overmold for a modular implantable medical device
US20060184210A1 (en) * 2003-05-16 2006-08-17 Medtronic, Inc. Explantation of implantable medical device
US20050004637A1 (en) * 2003-05-16 2005-01-06 Ruchika Singhal Explantation of implantable medical device
US20060195156A1 (en) * 2003-05-16 2006-08-31 Medtronic, Inc. Explantation of implantable medical device
US20050004619A1 (en) * 2003-05-16 2005-01-06 Wahlstrand Carl D. Headset recharger for cranially implantable medical devices
US7263401B2 (en) 2003-05-16 2007-08-28 Medtronic, Inc. Implantable medical device with a nonhermetic battery
US7881796B2 (en) 2003-05-16 2011-02-01 Medtronic, Inc. Implantable medical device with a nonhermetic battery
US7317947B2 (en) 2003-05-16 2008-01-08 Medtronic, Inc. Headset recharger for cranially implantable medical devices
US20080021511A1 (en) * 2003-05-16 2008-01-24 Medtronic, Inc. Implantable medical device with a nonhermetic battery
US20080065173A1 (en) * 2003-05-16 2008-03-13 Medtronic, Inc. Headset recharger for cranially implantable medical devices
US20050004618A1 (en) * 2003-05-16 2005-01-06 Scott Erik R. Implantable medical device with a nonhermetic battery
US20050003268A1 (en) * 2003-05-16 2005-01-06 Scott Erik R. Battery housing configuration
US10188440B2 (en) 2003-07-15 2019-01-29 Spinal Generations, Llc Method and device for delivering medicine to bone
US20100262089A1 (en) * 2003-07-15 2010-10-14 Spinal Generations, Llc Method and device for delivering medicine to bone
US8808337B2 (en) 2003-07-15 2014-08-19 Spinal Generations, Llc Method and device for delivering medicine to bone
US20090204158A1 (en) * 2003-07-15 2009-08-13 Spinal Generations, Llc Method and device for delivering medicine to bone
US8870836B2 (en) 2003-07-15 2014-10-28 Spinal Generations, Llc Method and device for delivering medicine to bone
US9445852B2 (en) 2003-07-15 2016-09-20 Spinal Generations, Llc Method and device for delivering medicine to bone
US8062270B2 (en) * 2003-07-15 2011-11-22 Spinal Generations, Llc Method and device for delivering medicine to bone
US9949777B2 (en) 2003-07-15 2018-04-24 Spinal Generations, Llc Method and device for delivering medicine to bone
US20050240156A1 (en) * 2004-04-27 2005-10-27 Conlon Sean P Method of implanting a fluid injection port
EP1591140A1 (en) 2004-04-27 2005-11-02 Ethicon Endo-Surgery, Inc. A surgically implantable injection port having a centered catheter connection tube
US20050240155A1 (en) * 2004-04-27 2005-10-27 Conlon Sean P Surgically implantable injection port having a centered catheter connection tube
US20090299380A1 (en) * 2004-04-29 2009-12-03 Medtronic, Inc. Implantation of implantable medical device
US7596399B2 (en) 2004-04-29 2009-09-29 Medtronic, Inc Implantation of implantable medical device
US20050245806A1 (en) * 2004-04-29 2005-11-03 Ruchika Singhal Implantation of implantable medical device
US8280478B2 (en) 2004-04-29 2012-10-02 Medtronic, Inc. Evaluation of implantation site for implantation of implantable medical device
US20090299164A1 (en) * 2004-04-29 2009-12-03 Medtronic, Inc. Implantation of implantable medical device
US20070074732A1 (en) * 2004-04-30 2007-04-05 Medtronic, Inc. Implantable medical device with lubricious material
US20050245984A1 (en) * 2004-04-30 2005-11-03 Medtronic, Inc. Implantable medical device with lubricious material
US9162072B2 (en) 2004-04-30 2015-10-20 Medtronic, Inc. Implantable medical device with lubricious material
US7862531B2 (en) 2004-06-25 2011-01-04 Optonol Ltd. Flow regulating implants
US8034016B2 (en) 2004-06-25 2011-10-11 Optonol, Ltd. Flow regulating implants and methods of implanting
US20080077071A1 (en) * 2004-06-25 2008-03-27 Optonol Ltd. Flow Regulating Implants
US20050288617A1 (en) * 2004-06-25 2005-12-29 Ira Yaron Flow regulating implants
US9744343B2 (en) * 2004-07-13 2017-08-29 Primo Medical Group, Inc. Volume reducing reservoir insert for an infusion port
US11224729B2 (en) * 2004-07-13 2022-01-18 Primo Medical Group, Inc. Volume reducing reservoir insert for an infusion port
US20180126140A1 (en) * 2004-07-13 2018-05-10 Primo Medical Group, Inc. Volume Reducing Reservoir Insert for an Infusion Port
US20120232501A1 (en) * 2004-07-13 2012-09-13 Std Med, Inc. Volume Reducing Reservoir Insert for an Infusion Port
US20100130943A1 (en) * 2005-05-06 2010-05-27 Medtronic Minimed, Inc. Infusion device and method with disposable portion
US20190054284A1 (en) * 2005-12-23 2019-02-21 Angiodynamics, Inc. Implantable Access Port
US20070255338A1 (en) * 2006-04-28 2007-11-01 Medtronic, Inc. Cranial implant
US9084901B2 (en) 2006-04-28 2015-07-21 Medtronic, Inc. Cranial implant
US9504402B2 (en) 2006-04-28 2016-11-29 Medtronic, Inc. Cranial implant
US20080195160A1 (en) * 2007-02-08 2008-08-14 Wingeier Brett M Refillable reservoir lead systems
US7813811B2 (en) 2007-02-08 2010-10-12 Neuropace, Inc. Refillable reservoir lead systems
US8190270B2 (en) 2007-02-08 2012-05-29 Neuropace, Inc. Refillable reservoir lead systems
US8160720B2 (en) 2007-02-08 2012-04-17 Neuropace, Inc. Refillable reservoir lead systems
US20080195227A1 (en) * 2007-02-08 2008-08-14 Boling C Lance Drug eluting lead systems
US8423156B2 (en) 2007-02-08 2013-04-16 Neuropace, Inc. Drug eluting lead systems
US20110004282A1 (en) * 2007-02-08 2011-01-06 Neuropace, Inc. Drug Eluting Lead Systems
US20100331762A1 (en) * 2007-02-08 2010-12-30 Neuropace, Inc. Refillable Reservoir Lead Systems
US7844345B2 (en) 2007-02-08 2010-11-30 Neuropace, Inc. Drug eluting lead systems
US8109896B2 (en) 2008-02-11 2012-02-07 Optonol Ltd. Devices and methods for opening fluid passageways
US20090204053A1 (en) * 2008-02-11 2009-08-13 Optonol Ltd. Devices and methods for opening fluid passageways
US20090281623A1 (en) * 2008-05-12 2009-11-12 Medtronic, Inc. Customization of implantable medical devices
US8152792B1 (en) * 2008-09-08 2012-04-10 Kornel Ezriel E Subcutaneous drain for a body cavity
US9393432B2 (en) 2008-10-31 2016-07-19 Medtronic, Inc. Non-hermetic direct current interconnect
US9173774B2 (en) 2010-03-26 2015-11-03 Optonol Ltd. Fluid drainage device, delivery device, and associated methods of use and manufacture
US9603644B2 (en) 2012-08-07 2017-03-28 Spinal Generations, Llc Methods and devices for delivery of medicine to bone
US10653470B2 (en) 2014-02-19 2020-05-19 Spinal Generation, LLC Compressible mixing and delivery system for medical substances
US11712278B2 (en) 2014-02-19 2023-08-01 Spinal Generations, Llc Compressible mixing and delivery system for medical substances
US9615863B2 (en) 2014-10-22 2017-04-11 Spinal Generations, Llc Multichannel cannula for kyphoplasty and method of use
US10517660B2 (en) 2014-10-22 2019-12-31 Spinal Generations, Llc Multichannel cannula for kyphoplasty and method of use
US11045632B2 (en) 2017-04-24 2021-06-29 Longeviti Neuro Solutions Llc Cerebral spinal fluid shunt plug
US11439798B2 (en) 2017-04-24 2022-09-13 Longeviti Neuro Solutions Llc Cerebral spinal fluid shunt plug

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