US3310051A - Surgical reservoir for implantation beneath the skin - Google Patents
Surgical reservoir for implantation beneath the skin Download PDFInfo
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- US3310051A US3310051A US329443A US32944363A US3310051A US 3310051 A US3310051 A US 3310051A US 329443 A US329443 A US 329443A US 32944363 A US32944363 A US 32944363A US 3310051 A US3310051 A US 3310051A
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- Prior art keywords
- wall
- passage
- capsule
- skin
- tube
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/02—Access sites
- A61M39/0208—Subcutaneous access sites for injecting or removing fluids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0687—Skull, cranium
Definitions
- This invention relates to a surgical implant which provides a reservoir located conveniently to the skin of a person which may be utilized to introduce, withdraw, or mix fluids in regions located farther inside the body.
- Still another object of the invention is to provide a mixing or flushing reservoir into which fluids may readily be injected or from which they may readily be withdrawn.
- An optional object is to provide such a reservoir which may also serve to provide surge-generatiug means of flush and mix fluids in it and in the region under treatment.
- a device comprises a tube having a central passage, the tube being adapted to be inserted in to the body so that its passage communicates with a selected region therein.
- a capsule is adapted to be connected to this tube and to be placed beneath the skin of the body.
- This capsule comprises an enclosure which has an internal periphery and a first and second wall, these walls facing each other inside the capsule. The wall next to the skin is tolerant to, and self-sealing after, needle puncture.
- One of the walls has a passage therethrough in fluid communication with the passage through the tube.
- one of the walls is flexible and palpable through the skin by force exerted by the hand.
- the material of the flexible wall is flexible enough to be moved toward the other wall and thereby reduce the volume of the capsule and also sufficiently springy to return to its normal unstressed condition, thereby providing for pumping means to create bi-directional flow in the passages for mixing purposes.
- FIG. 1 is a cross-section of a portion of a skull, showing the device of the invention, partly in cutaway crosssection and in its normal, unstressed condition;
- FIG. 2 is a top view of the invention, partly in cutaway cross-section
- FIG. 3 is a bottom view of the device taken at line 33 of FIG. 1;
- FIG. 4 is a fragmentary cross-section of a portion of FIG. 1, showing the device in another of its conditions.
- FIG. 1 illustrates a skull 10, showing the scalp 11 and the bone 12 of the skull surrounding the brain 13.
- the drawing of the anotomical portions is simplified because these form no portion of the present invention.
- the device is installed within a burr hole 14 having an internal wall 15 in the bone of the skull, and is held beneath the skin of the scalp by means of a sutured slit 16.
- the reservoir elements 20 comprising the invention includes a tube 21 having a central passage 22 and a closed end 23. Perforations 24 through the wall provide for fluid communication between the passage and the outside of the tube.
- the tube is connected to a capsule 25 by means of a connector 26, which connector is attached to a passage extension 27 which has a passage 28 that enters the capsule itself through one wall thereof.
- the capsule has a boss 29 which fits within burr hole 14 and provides for lateral restraint of the device. The capsule outward of the boss rests on the skull so as to give longitudinal restraint.
- the capsule is a continuou enclosure and includes a circumferential periphery defined by circumferential edge 30.
- First and second interior walls 31, 32 are provided on opposite sides of the periphery.
- the first wall lies closer to the skull, and includes an interior crown 33 which surrounds the opening 34 of passage 28 into the interior of the capsule.
- the crown has a plurality of notches 35 formed therein.
- Second wall 32 is generally domed and has a central section which is thicker than the edges. This wall is flexible and, as best shown in FIG. 4, is adapted to be palpated by finger pressure through the scalp to move it toward the first wall, thereby reducing the volume of the capsule.
- the crown is provided to hold them apart. However, the notches provide for fluid flow past the crown to the passage even when the second wall is pressed against the crown.
- the entire structure is, of course, made of material which is compatible with the human tissue with which it comes in contact.
- a convenient substance is silicone rubber manufactured by Dow Corning Company, of Midland, Mich.
- the thickness of the second wall is selected such that it is springy enough to restore itself to its normal, unstressed condition shown in FIG. 1, and yet sufliciently flexible that it can be deflected to the configuration shown in FIG. 4. It is also tolerant to repetitive needle punctures (with a resonable number), because, as best shown in FIG. 1, material may be in- 3 jected from a hypodermic syringe 36 by puncturing the scalp and the second wall with the needle. When the needle is withdrawn, the material of the second wall will seal the opening made by the needle.
- the tube will be forced into this region by means well known in the surgical arts. Once in place, this tube is connected to the capsule, and the capsule is placed in position as shown, and the scalp sutured over the capsule.
- the capsule is filled with fluid, which, after a time, will be identical with fluid in the region under study, particularly if the device is pumped for a while, either by depressing the second wall or by pumping with a syringe.
- the fluid may be withdrawn for sampling by a hypodermic syringe.
- medication may be introduced to the region by a syringe as shown, mixing being attained either by depressing the second wall or by pumping with the syringe.
- this device provides a reservoir of fluid which in effect is an extension of a region under treatment or study. Only one puncture of the brain or other region is necessary because the tube remains in place for sensible periods of time to provide a continuously-available conduit to the region, and the dome i available for introduction and withdrawal of material even were the second wall to be too stifl to flex. On the other hand, should the device be made flexible enough for this purpose, then even better results may be attained as a result of the more complete bi-directional flow attainable thereby.
- a reservoir element for implantation in a human being comprising: a tube having a central passage and adapted to be inserted into the body so that its passage communicates with a selected region to be treated; and
- a capsule of a size to be placed beneath the skin so as to rest between the skin and the bony structure of the body said capsule comprising an envelope having an in ner cavity bounded by a first and a second wall, the first wall being adapted to lay on surface to surface contact with said bony structure, the second wall being domed and springily flexible so as to be deformable and movable toward the first wall so as to reduce the volume of the cavity as the result of external force thereon, and to return to its dome shape of its own accord when the force is removed, there being a passage through said first wall connected to the passage in the tube, and a crown formed inside the cavity around the entrance of the passage thereinto, said cr-own having notches thereon, whereby the walls are prevented from adhering to each other and also from shutting off flow through the passage when the capsule is compressed, the second wall being made of material which permits puncture by a needle and is self-sealing after the needle is withdrawn.
- a reservoir element according to claim 1 in which a boss surrounds the capsule passage on the outside surface of the first wall, whereby to fit in a hole in the said bony structure and thereby to provide lateral positioning support for the capsule.
Description
arch 21, 1967 R. R. SCHULTE 3,31%051 SURGICAL RESERVOIR FOR IMPLANTATION BENEATH THE SKIN Filed Dec. 10, 1963 SCALP-// rfmaw United States Patent 3,310,051 SURGICAL RESERVGIR FOR Iii PLANTATION BENEATH THE SKIN Rudolf R. Schulte, 3328 Calle Fresno, Santa Barbara, Calif. 93185 Filed Dec. 10, 1963, Ser. No. 329,443 2 Claims. (Cl. 128-216) This invention relates to a surgical implant which provides a reservoir located conveniently to the skin of a person which may be utilized to introduce, withdraw, or mix fluids in regions located farther inside the body.
There are numerous instances Where repetitive samplings of body fluids need to be made, or in which repetitive introductions or medication must be made to interior regions. An example i the repetitive sampling of cerebro-spinal fluid, and vthe introduction of medication thereto, such as in the treatment of cryptococcal meningitis or tubercular meningitis. Medication for these diseases is often only marginally effective if given intravenously, because in order to supply the concentration needed at the situs of the ailment, the total dosage in the body would have to be too high. In fact, these diseases have been unmanageable with intravenous injections principally for this reason. However, if the medications are injected at the situs of the ailment, the local concentration can be made high enough to be effective, and the diseases may be controlled, even though the total dosage in the body is relatively low.
A concurrent problem associated with the foregoing is that concentration levels need to be maintained at the situs over a protracted period of time. To make repeated injections by means of repetitive punctures is obviously undesirable, and in many regions of the body soon becomes impossible. One reason is that fibrosis develops around t-he multiple needle tracks and renders access increasingly diflicult, particularly in the brain. Furthermore, repeated punctures of the brain are inherently undesirable. While the examples given in this specification relate to treatment of regions within the skull, clearly the same criteria apply to ailments in other regions of the body.
It is an object of this invention to provide a device which, once installed, gives continuous access to internal regions of the body without requiring additional needle penetrations into these regions. Instead, a tubular portion of the device remains in the body and extends to the affected area where it serves as a continuously-available conduit placed there but once. Thereafter, a syringe or other device need only be placed in fluid communication with this conduit to inject, Withdraw or mix fluids in the interior region.
Still another object of the invention is to provide a mixing or flushing reservoir into which fluids may readily be injected or from which they may readily be withdrawn. An optional object is to provide such a reservoir which may also serve to provide surge-generatiug means of flush and mix fluids in it and in the region under treatment.
A device according to this invention comprises a tube having a central passage, the tube being adapted to be inserted in to the body so that its passage communicates with a selected region therein. A capsule is adapted to be connected to this tube and to be placed beneath the skin of the body. This capsule comprises an enclosure which has an internal periphery and a first and second wall, these walls facing each other inside the capsule. The wall next to the skin is tolerant to, and self-sealing after, needle puncture. One of the walls has a passage therethrough in fluid communication with the passage through the tube.
According to a preferred but optional feature of the invention, one of the walls is flexible and palpable through the skin by force exerted by the hand. The material of the flexible wall is flexible enough to be moved toward the other wall and thereby reduce the volume of the capsule and also sufficiently springy to return to its normal unstressed condition, thereby providing for pumping means to create bi-directional flow in the passages for mixing purposes.
The above and other features of this invention will be fully understood from the following detailed description and the accompanying drawings in which:
FIG. 1 is a cross-section of a portion of a skull, showing the device of the invention, partly in cutaway crosssection and in its normal, unstressed condition;
FIG. 2 is a top view of the invention, partly in cutaway cross-section;
FIG. 3 is a bottom view of the device taken at line 33 of FIG. 1; and
FIG. 4 is a fragmentary cross-section of a portion of FIG. 1, showing the device in another of its conditions.
FIG. 1 illustrates a skull 10, showing the scalp 11 and the bone 12 of the skull surrounding the brain 13. The drawing of the anotomical portions is simplified because these form no portion of the present invention. It will be noted that the device is installed within a burr hole 14 having an internal wall 15 in the bone of the skull, and is held beneath the skin of the scalp by means of a sutured slit 16.
The reservoir elements 20 comprising the invention includes a tube 21 having a central passage 22 and a closed end 23. Perforations 24 through the wall provide for fluid communication between the passage and the outside of the tube. The tube is connected to a capsule 25 by means of a connector 26, which connector is attached to a passage extension 27 which has a passage 28 that enters the capsule itself through one wall thereof. The capsule has a boss 29 which fits within burr hole 14 and provides for lateral restraint of the device. The capsule outward of the boss rests on the skull so as to give longitudinal restraint.
The capsule is a continuou enclosure and includes a circumferential periphery defined by circumferential edge 30. First and second interior walls 31, 32 are provided on opposite sides of the periphery. The first wall lies closer to the skull, and includes an interior crown 33 which surrounds the opening 34 of passage 28 into the interior of the capsule. The crown has a plurality of notches 35 formed therein.
The entire structure is, of course, made of material which is compatible with the human tissue with which it comes in contact. A convenient substance is silicone rubber manufactured by Dow Corning Company, of Midland, Mich. The thickness of the second wall is selected such that it is springy enough to restore itself to its normal, unstressed condition shown in FIG. 1, and yet sufliciently flexible that it can be deflected to the configuration shown in FIG. 4. It is also tolerant to repetitive needle punctures (with a resonable number), because, as best shown in FIG. 1, material may be in- 3 jected from a hypodermic syringe 36 by puncturing the scalp and the second wall with the needle. When the needle is withdrawn, the material of the second wall will seal the opening made by the needle.
The use of the device should be evident from the foregoing. If it is desired either to withdraw fluid from region 37 within the brain or to introduce medication thereto, the tube will be forced into this region by means well known in the surgical arts. Once in place, this tube is connected to the capsule, and the capsule is placed in position as shown, and the scalp sutured over the capsule. The capsule is filled with fluid, which, after a time, will be identical with fluid in the region under study, particularly if the device is pumped for a while, either by depressing the second wall or by pumping with a syringe. The fluid may be withdrawn for sampling by a hypodermic syringe. Also, medication may be introduced to the region by a syringe as shown, mixing being attained either by depressing the second wall or by pumping with the syringe.
It will thereby be seen that this device provides a reservoir of fluid which in effect is an extension of a region under treatment or study. Only one puncture of the brain or other region is necessary because the tube remains in place for sensible periods of time to provide a continuously-available conduit to the region, and the dome i available for introduction and withdrawal of material even were the second wall to be too stifl to flex. On the other hand, should the device be made flexible enough for this purpose, then even better results may be attained as a result of the more complete bi-directional flow attainable thereby.
This invention is not to be limited by the embodiment shown in the drawings and described in the description which is given by way of example and not of limitation, but only in accordance with the scope of the appended claims.
I claim:
1. A reservoir element for implantation in a human being comprising: a tube having a central passage and adapted to be inserted into the body so that its passage communicates with a selected region to be treated; and
a capsule of a size to be placed beneath the skin so as to rest between the skin and the bony structure of the body, said capsule comprising an envelope having an in ner cavity bounded by a first and a second wall, the first wall being adapted to lay on surface to surface contact with said bony structure, the second wall being domed and springily flexible so as to be deformable and movable toward the first wall so as to reduce the volume of the cavity as the result of external force thereon, and to return to its dome shape of its own accord when the force is removed, there being a passage through said first wall connected to the passage in the tube, and a crown formed inside the cavity around the entrance of the passage thereinto, said cr-own having notches thereon, whereby the walls are prevented from adhering to each other and also from shutting off flow through the passage when the capsule is compressed, the second wall being made of material which permits puncture by a needle and is self-sealing after the needle is withdrawn.
2. A reservoir element according to claim 1 in which a boss surrounds the capsule passage on the outside surface of the first wall, whereby to fit in a hole in the said bony structure and thereby to provide lateral positioning support for the capsule.
References Cited by the Examiner UNITED STATES PATENTS 513,238 1/1894 Lalonde 128-126 3,021,842 2/1962 Flood 128215 3,111,125 11/1963 Schulte 128350 3,144,866 8/1964 Ellis 128232 3,154,074 10/1964 Harrison l28232 FOREIGN PATENTS 790,220 2/ 1958 Great Britain.
OTHER REFERENCES Lancet, vol 2 (63), No. 7315, Nov. 9, 1963, pp. 983-84.
RICHARD A. GAUDET, Primary Examiner.
DALTON L, TRULUCK, Examiner.
Claims (1)
1. A RESERVOIR ELEMENT FOR IMPLANTATION IN A HUMAN BEING COMPRISING: A TUBE HAVING A CENTRAL PASSAGE AND ADAPTED TO BE INSERTED INTO THE BODY SO THAT ITS PASSAGE COMMUNICATES WITH A SELECTED REGION TO BE TREATED; AND A CAPSULE OF A SIZE TO BE PLACED BENEATH THE SKIN SO AS TO REST BETWEEN THE SKIN AND THE BONY STRUCTURE OF THE BODY, SAID CAPSULE COMPRISING AN ENVELOPE HAVING AN INNER CAVITY BOUNDED BY A FIRST AND A SECOND WALL, THE FIRST WALL BEING ADAPTED TO LAY ON SURFACE TO SURFACE CONTACT WITH SAID BONY STRUCTURE, THE SECOND WALL BEING DOMED AND SPRINGILY FLEXIBLE SO AS TO BE DEFORMABLE AND MOVABLE TOWARD THE FIRST WALL SO AS TO BE DEFORMABLE AND OF THE CAVITY AS THE RESULT OF EXTERNAL FORCE THEREON, AND TO RETURN TO ITS DOME SHAPE OF ITS OWN ACCORD WHEN THE FORCE IS REMOVED, THERE BEING A PASSAGE THROUGH SAID FIRST WALL CONNECTED TO THE PASSAGE IN THE TUBE, AND A CROWN FORMED INSIDE THE CAVITY AROUND THE ENTRANCE OF THE PASSAGE THEREINTO, SAID CROWN HAVING NOTCHES THEREON, WHEREBY THE WALLS ARE PREVENTED FROM ADHERING TO EACH OTHER AND ALSO FROM SHUTTING OFF FLOW THROUGH THE PASSAGE WHEN THE CAPSULE IS COMPRESSED, THE SECOND WALL BEING MADE OF MATERIAL WHICH PERMITS PUNCTURE BY A NEEDLE AND IS SELF-SEALING AFTER THE NEEDLE IS WITHDRAWN.
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US329443A US3310051A (en) | 1963-12-10 | 1963-12-10 | Surgical reservoir for implantation beneath the skin |
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US329443A US3310051A (en) | 1963-12-10 | 1963-12-10 | Surgical reservoir for implantation beneath the skin |
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Cited By (97)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3530492A (en) * | 1967-12-05 | 1970-09-22 | Jack R Ferber | Method and apparatus for administering hypodermic injections |
US3613663A (en) * | 1968-09-09 | 1971-10-19 | Roger P Johnson | Apparatus to provide communication with the veins of a patient |
DE2124062A1 (en) * | 1970-05-18 | 1971-12-23 | The Regents of the University of Minnesota, Minneapolis, Minn. (V.StA.) | Implantable infusion pump |
US3640269A (en) * | 1969-10-24 | 1972-02-08 | Jose M R Delgado | Fluid-conducting instrument insertable in living organisms |
FR2135326A1 (en) * | 1971-05-06 | 1972-12-15 | Gulf Oil Corp | |
US3731681A (en) * | 1970-05-18 | 1973-05-08 | Univ Minnesota | Implantable indusion pump |
US3765414A (en) * | 1972-03-10 | 1973-10-16 | Hydro Med Sciences Inc | Drug release system |
US3796217A (en) * | 1972-03-10 | 1974-03-12 | Hydr Med Sciences Inc | Drug release system |
US3831583A (en) * | 1971-03-05 | 1974-08-27 | Univ California | Implantable bulb for inflation of surgical implements |
US3864874A (en) * | 1973-01-29 | 1975-02-11 | Dale M Norris | Method and apparatus for introducing a fluid into the vascular system of a tree or similar plant |
US3958562A (en) * | 1974-05-30 | 1976-05-25 | Hakim Company Limited | Implantable pressure sensor |
US3971376A (en) * | 1973-02-26 | 1976-07-27 | Ceskoslovenska Akademie Ved | Method and apparatus for introducing fluids into the body |
US3998222A (en) * | 1974-04-15 | 1976-12-21 | Shihata Alfred A | Subcutaneous arterio-venous shunt with valve |
US4013074A (en) * | 1974-06-21 | 1977-03-22 | Siposs George G | Implantable medication-dispensing device |
US4026287A (en) * | 1975-12-10 | 1977-05-31 | Irene Haller | Syringe with retractable cannula |
DE2724231A1 (en) * | 1977-05-25 | 1978-11-30 | Affeld Klaus | Collecting container for spermatozoa - includes suture ring implanted over epididymis and tube leading to tap capsule |
US4160454A (en) * | 1975-07-09 | 1979-07-10 | University Of Utah | Implantable catheter system |
US4184497A (en) * | 1977-08-26 | 1980-01-22 | University Of Utah | Peritoneal dialysis catheter |
US4190057A (en) * | 1977-12-27 | 1980-02-26 | Thoratec Laboratories Corporation | Device for determining the patentcy of a blood vessel |
US4253201A (en) * | 1979-05-24 | 1981-03-03 | Ross David A | Prosthesis with self-sealing valve |
US4317452A (en) * | 1980-02-04 | 1982-03-02 | C. R. Bard, Inc. | Body fluid drain |
US4405305A (en) * | 1980-10-27 | 1983-09-20 | University Of Utah Research Foundation | Subcutaneous peritoneal injection catheter |
US4464178A (en) * | 1981-11-25 | 1984-08-07 | Dalton Michael J | Method and apparatus for administration of fluids |
FR2551348A1 (en) * | 1983-09-02 | 1985-03-08 | Meriaux Henri | INFUSION DEVICE |
EP0134340A1 (en) * | 1983-08-22 | 1985-03-20 | The University of Utah Research Foundation | Peritoneal injection catheter apparatus |
US4557724A (en) * | 1981-02-17 | 1985-12-10 | University Of Utah Research Foundation | Apparatus and methods for minimizing cellular adhesion on peritoneal injection catheters |
US4559033A (en) * | 1980-10-27 | 1985-12-17 | University Of Utah Research Foundation | Apparatus and methods for minimizing peritoneal injection catheter obstruction |
US4569675A (en) * | 1983-09-12 | 1986-02-11 | Infusaid Corporation | Transcutaneous infusion system |
US4585010A (en) * | 1984-07-02 | 1986-04-29 | Enrico Ascer | Process and apparatus for measurement of outflow resistance |
US4634424A (en) * | 1984-04-23 | 1987-01-06 | Windsor Medical, Inc. | Multiple re-entry implantable septum and method of using same |
US4673394A (en) * | 1986-01-17 | 1987-06-16 | Strato Medical Corporation | Implantable treatment reservoir |
US4687001A (en) * | 1977-02-14 | 1987-08-18 | The United States Of America As Represented By The Department Of Health And Human Services | Subcutaneous fluid and culture chamber and implant technique |
US4710177A (en) * | 1986-05-15 | 1987-12-01 | Smith Robert R | Subcutaneous ventricular injection apparatus and method |
US4710167A (en) * | 1985-05-21 | 1987-12-01 | Applied Precision Limited | Implantable device for chronically injecting a substance, in particular a therapeutant |
US4710174A (en) * | 1985-12-16 | 1987-12-01 | Surgical Engineering Associates, Inc. | Implantable infusion port |
US4767410A (en) * | 1985-12-16 | 1988-08-30 | Surgical Engineering Associates, Inc. | Implantable infusion port |
US4772261A (en) * | 1987-01-29 | 1988-09-20 | Board Of Regents, The University Of Texas System | Intramedullary catheter |
US4772270A (en) * | 1987-06-18 | 1988-09-20 | Catheter Technology Corp. | Inseparable port/catheter tube assembly and methods |
US4772276A (en) * | 1987-06-18 | 1988-09-20 | Catheter Technology Corp. | Catheter tube coupling assembly and methods |
US4781695A (en) * | 1986-07-11 | 1988-11-01 | Dalton Michael J | Implantable fluid dispenser |
EP0309092A1 (en) * | 1987-08-25 | 1989-03-29 | Infusaid, Inc. | Implantable device |
US4857053A (en) * | 1988-08-29 | 1989-08-15 | Dalton Michael J | Matrix septum |
US4904241A (en) * | 1986-10-16 | 1990-02-27 | Medical Engineering Corp. | Septum with a needle stop at the fluid transfer port |
US4915690A (en) * | 1988-02-02 | 1990-04-10 | C. R. Bard, Inc. | Micro-injection port |
US4969870A (en) * | 1989-06-07 | 1990-11-13 | The Regents Of The University Of California | Method and apparatus for intraosseous infusions |
US5041098A (en) * | 1989-05-19 | 1991-08-20 | Strato Medical Corporation | Vascular access system for extracorporeal treatment of blood |
US5092849A (en) * | 1987-08-25 | 1992-03-03 | Shiley Infusaid, Inc. | Implantable device |
US5122114A (en) * | 1991-02-01 | 1992-06-16 | Board Of Regents, University Of Texas System | Method of using intramedullary catheter |
US5312364A (en) * | 1993-08-06 | 1994-05-17 | Pyng | Intraosseous infusion device |
US5332398A (en) * | 1992-02-01 | 1994-07-26 | Board Of Regents, The University Of Texas System | Intramedullary catheter |
US5399168A (en) * | 1991-08-29 | 1995-03-21 | C. R. Bard, Inc. | Implantable plural fluid cavity port |
WO1996014834A1 (en) * | 1994-11-10 | 1996-05-23 | University Of Kentucky Research Foundation | Implantable refillable controlled release device to deliver drugs directly to an internal portion of the body |
US5702414A (en) * | 1995-05-14 | 1997-12-30 | Optonol Ltd | Method of implanting an intraocular implant |
US5713858A (en) * | 1995-04-28 | 1998-02-03 | Medtronic, Inc. | Permanently implantable guiding catheter |
US5792104A (en) * | 1996-12-10 | 1998-08-11 | Medtronic, Inc. | Dual-reservoir vascular access port |
US5817052A (en) * | 1995-12-26 | 1998-10-06 | Pyng Medical Corp. | Apparatus for intraosseous infusion or aspiration |
US5848989A (en) * | 1997-06-05 | 1998-12-15 | Davinci Biomedical Research Products, Inc. | Implantable port with low profile housing for delivery/collection of fluids and implantation method |
US5968058A (en) * | 1996-03-27 | 1999-10-19 | Optonol Ltd. | Device for and method of implanting an intraocular implant |
US6036721A (en) * | 1996-11-16 | 2000-03-14 | Cap Incorporated | Puncture closure |
US6203513B1 (en) | 1997-11-20 | 2001-03-20 | Optonol Ltd. | Flow regulating implant, method of manufacture, and delivery device |
US6478783B1 (en) | 2000-05-26 | 2002-11-12 | H. Robert Moorehead | Anti-sludge medication ports and related methods |
US6558342B1 (en) | 1999-06-02 | 2003-05-06 | Optonol Ltd. | Flow control device, introducer and method of implanting |
US6623462B2 (en) | 2001-05-11 | 2003-09-23 | Harmac Medical Products, Inc. | Needle safety guard |
US6726678B1 (en) * | 2001-02-22 | 2004-04-27 | Isurgical, Llc | Implantable reservoir and system for delivery of a therapeutic agent |
US6736797B1 (en) | 1998-06-19 | 2004-05-18 | Unomedical A/S | Subcutaneous infusion set |
EP1426074A1 (en) * | 1995-04-28 | 2004-06-09 | Medtronic Inc. | Securing device for intracranial infusion port with filter and catheter |
US20040176814A1 (en) * | 2002-12-09 | 2004-09-09 | Ruchika Singhal | Overmold for a modular implantable medical device |
US6824530B2 (en) | 2001-05-11 | 2004-11-30 | Harmac Medical Products, Inc. | Combination needle assembly and needle safety guard |
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US20050003268A1 (en) * | 2003-05-16 | 2005-01-06 | Scott Erik R. | Battery housing configuration |
US20050004620A1 (en) * | 2002-12-09 | 2005-01-06 | Medtronic, Inc. | Implantable medical device with anti-infection agent |
US20050004637A1 (en) * | 2003-05-16 | 2005-01-06 | Ruchika Singhal | Explantation of implantable medical device |
US20050004619A1 (en) * | 2003-05-16 | 2005-01-06 | Wahlstrand Carl D. | Headset recharger for cranially implantable medical devices |
US20050240155A1 (en) * | 2004-04-27 | 2005-10-27 | Conlon Sean P | Surgically implantable injection port having a centered catheter connection tube |
US20050240156A1 (en) * | 2004-04-27 | 2005-10-27 | Conlon Sean P | Method of implanting a fluid injection port |
US20050245984A1 (en) * | 2004-04-30 | 2005-11-03 | Medtronic, Inc. | Implantable medical device with lubricious material |
US20050245806A1 (en) * | 2004-04-29 | 2005-11-03 | Ruchika Singhal | Implantation of implantable medical device |
US20050288617A1 (en) * | 2004-06-25 | 2005-12-29 | Ira Yaron | Flow regulating implants |
US20070255338A1 (en) * | 2006-04-28 | 2007-11-01 | Medtronic, Inc. | Cranial implant |
US20080195160A1 (en) * | 2007-02-08 | 2008-08-14 | Wingeier Brett M | Refillable reservoir lead systems |
US20080195227A1 (en) * | 2007-02-08 | 2008-08-14 | Boling C Lance | Drug eluting lead systems |
US20090204158A1 (en) * | 2003-07-15 | 2009-08-13 | Spinal Generations, Llc | Method and device for delivering medicine to bone |
US20090204053A1 (en) * | 2008-02-11 | 2009-08-13 | Optonol Ltd. | Devices and methods for opening fluid passageways |
US20090281623A1 (en) * | 2008-05-12 | 2009-11-12 | Medtronic, Inc. | Customization of implantable medical devices |
US20100130943A1 (en) * | 2005-05-06 | 2010-05-27 | Medtronic Minimed, Inc. | Infusion device and method with disposable portion |
US20100262089A1 (en) * | 2003-07-15 | 2010-10-14 | Spinal Generations, Llc | Method and device for delivering medicine to bone |
US20100274259A1 (en) * | 1997-11-20 | 2010-10-28 | Optonol Ltd. | Fluid drainage device, delivery device, and associated methods of use and manufacture |
US8152792B1 (en) * | 2008-09-08 | 2012-04-10 | Kornel Ezriel E | Subcutaneous drain for a body cavity |
US20120232501A1 (en) * | 2004-07-13 | 2012-09-13 | Std Med, Inc. | Volume Reducing Reservoir Insert for an Infusion Port |
US8870836B2 (en) | 2003-07-15 | 2014-10-28 | Spinal Generations, Llc | Method and device for delivering medicine to bone |
US9393432B2 (en) | 2008-10-31 | 2016-07-19 | Medtronic, Inc. | Non-hermetic direct current interconnect |
US9603644B2 (en) | 2012-08-07 | 2017-03-28 | Spinal Generations, Llc | Methods and devices for delivery of medicine to bone |
US9615863B2 (en) | 2014-10-22 | 2017-04-11 | Spinal Generations, Llc | Multichannel cannula for kyphoplasty and method of use |
US20190054284A1 (en) * | 2005-12-23 | 2019-02-21 | Angiodynamics, Inc. | Implantable Access Port |
US10653470B2 (en) | 2014-02-19 | 2020-05-19 | Spinal Generation, LLC | Compressible mixing and delivery system for medical substances |
US11045632B2 (en) | 2017-04-24 | 2021-06-29 | Longeviti Neuro Solutions Llc | Cerebral spinal fluid shunt plug |
US11439798B2 (en) | 2017-04-24 | 2022-09-13 | Longeviti Neuro Solutions Llc | Cerebral spinal fluid shunt plug |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US513238A (en) * | 1894-01-23 | Joseph lalonde | ||
GB790220A (en) * | 1954-09-14 | 1958-02-05 | Adolfo Scholcoff Elinger | Hypodermic syringe ampulla |
US3021842A (en) * | 1958-11-05 | 1962-02-20 | John F Flood | Hypodermic needle guide |
US3111125A (en) * | 1961-11-06 | 1963-11-19 | Rudolf R Schulte | Drainage device |
US3144866A (en) * | 1961-08-11 | 1964-08-18 | Briggs Castling & Kelly | Disposable douche syringe and bag |
US3154074A (en) * | 1962-10-23 | 1964-10-27 | Lehn & Fink Products Corp | Internal medicament applicator |
-
1963
- 1963-12-10 US US329443A patent/US3310051A/en not_active Expired - Lifetime
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US513238A (en) * | 1894-01-23 | Joseph lalonde | ||
GB790220A (en) * | 1954-09-14 | 1958-02-05 | Adolfo Scholcoff Elinger | Hypodermic syringe ampulla |
US3021842A (en) * | 1958-11-05 | 1962-02-20 | John F Flood | Hypodermic needle guide |
US3144866A (en) * | 1961-08-11 | 1964-08-18 | Briggs Castling & Kelly | Disposable douche syringe and bag |
US3111125A (en) * | 1961-11-06 | 1963-11-19 | Rudolf R Schulte | Drainage device |
US3154074A (en) * | 1962-10-23 | 1964-10-27 | Lehn & Fink Products Corp | Internal medicament applicator |
Cited By (160)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3530492A (en) * | 1967-12-05 | 1970-09-22 | Jack R Ferber | Method and apparatus for administering hypodermic injections |
US3613663A (en) * | 1968-09-09 | 1971-10-19 | Roger P Johnson | Apparatus to provide communication with the veins of a patient |
US3640269A (en) * | 1969-10-24 | 1972-02-08 | Jose M R Delgado | Fluid-conducting instrument insertable in living organisms |
DE2124062A1 (en) * | 1970-05-18 | 1971-12-23 | The Regents of the University of Minnesota, Minneapolis, Minn. (V.StA.) | Implantable infusion pump |
US3731681A (en) * | 1970-05-18 | 1973-05-08 | Univ Minnesota | Implantable indusion pump |
US3831583A (en) * | 1971-03-05 | 1974-08-27 | Univ California | Implantable bulb for inflation of surgical implements |
FR2135326A1 (en) * | 1971-05-06 | 1972-12-15 | Gulf Oil Corp | |
US3783868A (en) * | 1971-05-06 | 1974-01-08 | Gulf Oil Corp | Percutaneous implant |
US3796217A (en) * | 1972-03-10 | 1974-03-12 | Hydr Med Sciences Inc | Drug release system |
US3765414A (en) * | 1972-03-10 | 1973-10-16 | Hydro Med Sciences Inc | Drug release system |
US3864874A (en) * | 1973-01-29 | 1975-02-11 | Dale M Norris | Method and apparatus for introducing a fluid into the vascular system of a tree or similar plant |
US3971376A (en) * | 1973-02-26 | 1976-07-27 | Ceskoslovenska Akademie Ved | Method and apparatus for introducing fluids into the body |
US3998222A (en) * | 1974-04-15 | 1976-12-21 | Shihata Alfred A | Subcutaneous arterio-venous shunt with valve |
US3958562A (en) * | 1974-05-30 | 1976-05-25 | Hakim Company Limited | Implantable pressure sensor |
US4013074A (en) * | 1974-06-21 | 1977-03-22 | Siposs George G | Implantable medication-dispensing device |
US4160454A (en) * | 1975-07-09 | 1979-07-10 | University Of Utah | Implantable catheter system |
US4026287A (en) * | 1975-12-10 | 1977-05-31 | Irene Haller | Syringe with retractable cannula |
US4687001A (en) * | 1977-02-14 | 1987-08-18 | The United States Of America As Represented By The Department Of Health And Human Services | Subcutaneous fluid and culture chamber and implant technique |
DE2724231A1 (en) * | 1977-05-25 | 1978-11-30 | Affeld Klaus | Collecting container for spermatozoa - includes suture ring implanted over epididymis and tube leading to tap capsule |
US4184497A (en) * | 1977-08-26 | 1980-01-22 | University Of Utah | Peritoneal dialysis catheter |
US4190057A (en) * | 1977-12-27 | 1980-02-26 | Thoratec Laboratories Corporation | Device for determining the patentcy of a blood vessel |
US4253201A (en) * | 1979-05-24 | 1981-03-03 | Ross David A | Prosthesis with self-sealing valve |
US4317452A (en) * | 1980-02-04 | 1982-03-02 | C. R. Bard, Inc. | Body fluid drain |
US4405305A (en) * | 1980-10-27 | 1983-09-20 | University Of Utah Research Foundation | Subcutaneous peritoneal injection catheter |
US4559033A (en) * | 1980-10-27 | 1985-12-17 | University Of Utah Research Foundation | Apparatus and methods for minimizing peritoneal injection catheter obstruction |
US4557724A (en) * | 1981-02-17 | 1985-12-10 | University Of Utah Research Foundation | Apparatus and methods for minimizing cellular adhesion on peritoneal injection catheters |
US4464178A (en) * | 1981-11-25 | 1984-08-07 | Dalton Michael J | Method and apparatus for administration of fluids |
EP0134340A1 (en) * | 1983-08-22 | 1985-03-20 | The University of Utah Research Foundation | Peritoneal injection catheter apparatus |
EP0134745A1 (en) * | 1983-09-02 | 1985-03-20 | Henri Meriaux | Infusion device |
FR2551348A1 (en) * | 1983-09-02 | 1985-03-08 | Meriaux Henri | INFUSION DEVICE |
US4569675A (en) * | 1983-09-12 | 1986-02-11 | Infusaid Corporation | Transcutaneous infusion system |
US4634424A (en) * | 1984-04-23 | 1987-01-06 | Windsor Medical, Inc. | Multiple re-entry implantable septum and method of using same |
US4585010A (en) * | 1984-07-02 | 1986-04-29 | Enrico Ascer | Process and apparatus for measurement of outflow resistance |
US4710167A (en) * | 1985-05-21 | 1987-12-01 | Applied Precision Limited | Implantable device for chronically injecting a substance, in particular a therapeutant |
US4710174A (en) * | 1985-12-16 | 1987-12-01 | Surgical Engineering Associates, Inc. | Implantable infusion port |
US4767410A (en) * | 1985-12-16 | 1988-08-30 | Surgical Engineering Associates, Inc. | Implantable infusion port |
US4673394A (en) * | 1986-01-17 | 1987-06-16 | Strato Medical Corporation | Implantable treatment reservoir |
US4710177A (en) * | 1986-05-15 | 1987-12-01 | Smith Robert R | Subcutaneous ventricular injection apparatus and method |
US4781695A (en) * | 1986-07-11 | 1988-11-01 | Dalton Michael J | Implantable fluid dispenser |
US4904241A (en) * | 1986-10-16 | 1990-02-27 | Medical Engineering Corp. | Septum with a needle stop at the fluid transfer port |
US4772261A (en) * | 1987-01-29 | 1988-09-20 | Board Of Regents, The University Of Texas System | Intramedullary catheter |
US4772270A (en) * | 1987-06-18 | 1988-09-20 | Catheter Technology Corp. | Inseparable port/catheter tube assembly and methods |
US4772276A (en) * | 1987-06-18 | 1988-09-20 | Catheter Technology Corp. | Catheter tube coupling assembly and methods |
US5092849A (en) * | 1987-08-25 | 1992-03-03 | Shiley Infusaid, Inc. | Implantable device |
EP0309092A1 (en) * | 1987-08-25 | 1989-03-29 | Infusaid, Inc. | Implantable device |
US4915690A (en) * | 1988-02-02 | 1990-04-10 | C. R. Bard, Inc. | Micro-injection port |
US4857053A (en) * | 1988-08-29 | 1989-08-15 | Dalton Michael J | Matrix septum |
US5041098A (en) * | 1989-05-19 | 1991-08-20 | Strato Medical Corporation | Vascular access system for extracorporeal treatment of blood |
US4969870A (en) * | 1989-06-07 | 1990-11-13 | The Regents Of The University Of California | Method and apparatus for intraosseous infusions |
WO1990014857A1 (en) * | 1989-06-07 | 1990-12-13 | The Regents Of The University Of California | Method and apparatus for intraosseous infusions and aspirations |
AU647399B2 (en) * | 1989-06-07 | 1994-03-24 | Regents Of The University Of California, The | Method and apparatus for intraosseous infusions and aspirations |
US5122114A (en) * | 1991-02-01 | 1992-06-16 | Board Of Regents, University Of Texas System | Method of using intramedullary catheter |
US5399168A (en) * | 1991-08-29 | 1995-03-21 | C. R. Bard, Inc. | Implantable plural fluid cavity port |
US6228088B1 (en) | 1992-02-01 | 2001-05-08 | Board Of Regents, The University Of Texas System | Combination drill bit and intrametullary catheter and method of using same |
US5332398A (en) * | 1992-02-01 | 1994-07-26 | Board Of Regents, The University Of Texas System | Intramedullary catheter |
US5312364A (en) * | 1993-08-06 | 1994-05-17 | Pyng | Intraosseous infusion device |
WO1996014834A1 (en) * | 1994-11-10 | 1996-05-23 | University Of Kentucky Research Foundation | Implantable refillable controlled release device to deliver drugs directly to an internal portion of the body |
US5836935A (en) * | 1994-11-10 | 1998-11-17 | Ashton; Paul | Implantable refillable controlled release device to deliver drugs directly to an internal portion of the body |
US5713858A (en) * | 1995-04-28 | 1998-02-03 | Medtronic, Inc. | Permanently implantable guiding catheter |
EP0822844B1 (en) * | 1995-04-28 | 2004-06-30 | Medtronic, Inc. | Securing device for intercranial infusion port with filter and catheter |
EP1426074A1 (en) * | 1995-04-28 | 2004-06-09 | Medtronic Inc. | Securing device for intracranial infusion port with filter and catheter |
US5702414A (en) * | 1995-05-14 | 1997-12-30 | Optonol Ltd | Method of implanting an intraocular implant |
US20040088048A1 (en) * | 1995-05-14 | 2004-05-06 | Jacob Richter | Intraocular implant, delivery device, and method of implantation |
US7481816B2 (en) | 1995-05-14 | 2009-01-27 | Optonol Ltd. | Intraocular implant, delivery device, and method of implantation |
US6468283B1 (en) | 1995-05-14 | 2002-10-22 | Optonol, Ltd. | Method of regulating pressure with an intraocular implant |
US5817052A (en) * | 1995-12-26 | 1998-10-06 | Pyng Medical Corp. | Apparatus for intraosseous infusion or aspiration |
US5968058A (en) * | 1996-03-27 | 1999-10-19 | Optonol Ltd. | Device for and method of implanting an intraocular implant |
US6036721A (en) * | 1996-11-16 | 2000-03-14 | Cap Incorporated | Puncture closure |
US5792104A (en) * | 1996-12-10 | 1998-08-11 | Medtronic, Inc. | Dual-reservoir vascular access port |
US5848989A (en) * | 1997-06-05 | 1998-12-15 | Davinci Biomedical Research Products, Inc. | Implantable port with low profile housing for delivery/collection of fluids and implantation method |
US6510600B2 (en) | 1997-11-20 | 2003-01-28 | Optonol, Ltd. | Method for manufacturing a flow regulating implant |
US8486086B2 (en) | 1997-11-20 | 2013-07-16 | Optonol, Ltd | Flow regulating implant, method of manufacture, and delivery device |
US20080125691A1 (en) * | 1997-11-20 | 2008-05-29 | Optonol Ltd. | Flow regulating implants |
US6203513B1 (en) | 1997-11-20 | 2001-03-20 | Optonol Ltd. | Flow regulating implant, method of manufacture, and delivery device |
US7670310B2 (en) | 1997-11-20 | 2010-03-02 | Optonol Ltd | Flow regulating implants |
US20100274259A1 (en) * | 1997-11-20 | 2010-10-28 | Optonol Ltd. | Fluid drainage device, delivery device, and associated methods of use and manufacture |
US20030079329A1 (en) * | 1997-11-20 | 2003-05-01 | Ira Yaron | Flow regulating implant, method of manufacture, and delivery device |
US8313454B2 (en) | 1997-11-20 | 2012-11-20 | Optonol Ltd. | Fluid drainage device, delivery device, and associated methods of use and manufacture |
US6736797B1 (en) | 1998-06-19 | 2004-05-18 | Unomedical A/S | Subcutaneous infusion set |
US6558342B1 (en) | 1999-06-02 | 2003-05-06 | Optonol Ltd. | Flow control device, introducer and method of implanting |
US6726664B2 (en) | 1999-06-02 | 2004-04-27 | Optonol Ltd. | Flow control device, introducer and method of implanting |
US6478783B1 (en) | 2000-05-26 | 2002-11-12 | H. Robert Moorehead | Anti-sludge medication ports and related methods |
US7063691B2 (en) | 2001-02-22 | 2006-06-20 | Regents Of The University Of Minnesota | Implantable reservoir and system for delivery of a therapeutic agent |
US20040176750A1 (en) * | 2001-02-22 | 2004-09-09 | Isurgical, Llc And Regents Of The University Of Minnesota | Implantable reservoir and system for delivery of a therapeutic agent |
US6726678B1 (en) * | 2001-02-22 | 2004-04-27 | Isurgical, Llc | Implantable reservoir and system for delivery of a therapeutic agent |
US20060253106A1 (en) * | 2001-02-22 | 2006-11-09 | Regents Of The University Of Minnesota, Isurgical, Llc | Implantable reservoir and system for delivery of a therapeutic agent |
US6824530B2 (en) | 2001-05-11 | 2004-11-30 | Harmac Medical Products, Inc. | Combination needle assembly and needle safety guard |
US6623462B2 (en) | 2001-05-11 | 2003-09-23 | Harmac Medical Products, Inc. | Needle safety guard |
US20040176814A1 (en) * | 2002-12-09 | 2004-09-09 | Ruchika Singhal | Overmold for a modular implantable medical device |
US20050004620A1 (en) * | 2002-12-09 | 2005-01-06 | Medtronic, Inc. | Implantable medical device with anti-infection agent |
US7596408B2 (en) | 2002-12-09 | 2009-09-29 | Medtronic, Inc. | Implantable medical device with anti-infection agent |
US8086313B2 (en) | 2002-12-09 | 2011-12-27 | Medtronic, Inc. | Implantable medical device with anti-infection agent |
US20090292327A1 (en) * | 2002-12-09 | 2009-11-26 | Medtronic, Inc. | Implantable medical device with anti-infection agent |
US20070185539A1 (en) * | 2002-12-09 | 2007-08-09 | Medtronic, Inc. | Overmold for a modular implantable medical device |
US7242982B2 (en) | 2002-12-09 | 2007-07-10 | Medtronic, Inc. | Overmold for a modular implantable medical device |
US20060184210A1 (en) * | 2003-05-16 | 2006-08-17 | Medtronic, Inc. | Explantation of implantable medical device |
US20050004637A1 (en) * | 2003-05-16 | 2005-01-06 | Ruchika Singhal | Explantation of implantable medical device |
US20060195156A1 (en) * | 2003-05-16 | 2006-08-31 | Medtronic, Inc. | Explantation of implantable medical device |
US20050004619A1 (en) * | 2003-05-16 | 2005-01-06 | Wahlstrand Carl D. | Headset recharger for cranially implantable medical devices |
US7263401B2 (en) | 2003-05-16 | 2007-08-28 | Medtronic, Inc. | Implantable medical device with a nonhermetic battery |
US7881796B2 (en) | 2003-05-16 | 2011-02-01 | Medtronic, Inc. | Implantable medical device with a nonhermetic battery |
US7317947B2 (en) | 2003-05-16 | 2008-01-08 | Medtronic, Inc. | Headset recharger for cranially implantable medical devices |
US20080021511A1 (en) * | 2003-05-16 | 2008-01-24 | Medtronic, Inc. | Implantable medical device with a nonhermetic battery |
US20080065173A1 (en) * | 2003-05-16 | 2008-03-13 | Medtronic, Inc. | Headset recharger for cranially implantable medical devices |
US20050004618A1 (en) * | 2003-05-16 | 2005-01-06 | Scott Erik R. | Implantable medical device with a nonhermetic battery |
US20050003268A1 (en) * | 2003-05-16 | 2005-01-06 | Scott Erik R. | Battery housing configuration |
US10188440B2 (en) | 2003-07-15 | 2019-01-29 | Spinal Generations, Llc | Method and device for delivering medicine to bone |
US20100262089A1 (en) * | 2003-07-15 | 2010-10-14 | Spinal Generations, Llc | Method and device for delivering medicine to bone |
US8808337B2 (en) | 2003-07-15 | 2014-08-19 | Spinal Generations, Llc | Method and device for delivering medicine to bone |
US20090204158A1 (en) * | 2003-07-15 | 2009-08-13 | Spinal Generations, Llc | Method and device for delivering medicine to bone |
US8870836B2 (en) | 2003-07-15 | 2014-10-28 | Spinal Generations, Llc | Method and device for delivering medicine to bone |
US9445852B2 (en) | 2003-07-15 | 2016-09-20 | Spinal Generations, Llc | Method and device for delivering medicine to bone |
US8062270B2 (en) * | 2003-07-15 | 2011-11-22 | Spinal Generations, Llc | Method and device for delivering medicine to bone |
US9949777B2 (en) | 2003-07-15 | 2018-04-24 | Spinal Generations, Llc | Method and device for delivering medicine to bone |
US20050240156A1 (en) * | 2004-04-27 | 2005-10-27 | Conlon Sean P | Method of implanting a fluid injection port |
EP1591140A1 (en) | 2004-04-27 | 2005-11-02 | Ethicon Endo-Surgery, Inc. | A surgically implantable injection port having a centered catheter connection tube |
US20050240155A1 (en) * | 2004-04-27 | 2005-10-27 | Conlon Sean P | Surgically implantable injection port having a centered catheter connection tube |
US20090299380A1 (en) * | 2004-04-29 | 2009-12-03 | Medtronic, Inc. | Implantation of implantable medical device |
US7596399B2 (en) | 2004-04-29 | 2009-09-29 | Medtronic, Inc | Implantation of implantable medical device |
US20050245806A1 (en) * | 2004-04-29 | 2005-11-03 | Ruchika Singhal | Implantation of implantable medical device |
US8280478B2 (en) | 2004-04-29 | 2012-10-02 | Medtronic, Inc. | Evaluation of implantation site for implantation of implantable medical device |
US20090299164A1 (en) * | 2004-04-29 | 2009-12-03 | Medtronic, Inc. | Implantation of implantable medical device |
US20070074732A1 (en) * | 2004-04-30 | 2007-04-05 | Medtronic, Inc. | Implantable medical device with lubricious material |
US20050245984A1 (en) * | 2004-04-30 | 2005-11-03 | Medtronic, Inc. | Implantable medical device with lubricious material |
US9162072B2 (en) | 2004-04-30 | 2015-10-20 | Medtronic, Inc. | Implantable medical device with lubricious material |
US7862531B2 (en) | 2004-06-25 | 2011-01-04 | Optonol Ltd. | Flow regulating implants |
US8034016B2 (en) | 2004-06-25 | 2011-10-11 | Optonol, Ltd. | Flow regulating implants and methods of implanting |
US20080077071A1 (en) * | 2004-06-25 | 2008-03-27 | Optonol Ltd. | Flow Regulating Implants |
US20050288617A1 (en) * | 2004-06-25 | 2005-12-29 | Ira Yaron | Flow regulating implants |
US9744343B2 (en) * | 2004-07-13 | 2017-08-29 | Primo Medical Group, Inc. | Volume reducing reservoir insert for an infusion port |
US11224729B2 (en) * | 2004-07-13 | 2022-01-18 | Primo Medical Group, Inc. | Volume reducing reservoir insert for an infusion port |
US20180126140A1 (en) * | 2004-07-13 | 2018-05-10 | Primo Medical Group, Inc. | Volume Reducing Reservoir Insert for an Infusion Port |
US20120232501A1 (en) * | 2004-07-13 | 2012-09-13 | Std Med, Inc. | Volume Reducing Reservoir Insert for an Infusion Port |
US20100130943A1 (en) * | 2005-05-06 | 2010-05-27 | Medtronic Minimed, Inc. | Infusion device and method with disposable portion |
US20190054284A1 (en) * | 2005-12-23 | 2019-02-21 | Angiodynamics, Inc. | Implantable Access Port |
US20070255338A1 (en) * | 2006-04-28 | 2007-11-01 | Medtronic, Inc. | Cranial implant |
US9084901B2 (en) | 2006-04-28 | 2015-07-21 | Medtronic, Inc. | Cranial implant |
US9504402B2 (en) | 2006-04-28 | 2016-11-29 | Medtronic, Inc. | Cranial implant |
US20080195160A1 (en) * | 2007-02-08 | 2008-08-14 | Wingeier Brett M | Refillable reservoir lead systems |
US7813811B2 (en) | 2007-02-08 | 2010-10-12 | Neuropace, Inc. | Refillable reservoir lead systems |
US8190270B2 (en) | 2007-02-08 | 2012-05-29 | Neuropace, Inc. | Refillable reservoir lead systems |
US8160720B2 (en) | 2007-02-08 | 2012-04-17 | Neuropace, Inc. | Refillable reservoir lead systems |
US20080195227A1 (en) * | 2007-02-08 | 2008-08-14 | Boling C Lance | Drug eluting lead systems |
US8423156B2 (en) | 2007-02-08 | 2013-04-16 | Neuropace, Inc. | Drug eluting lead systems |
US20110004282A1 (en) * | 2007-02-08 | 2011-01-06 | Neuropace, Inc. | Drug Eluting Lead Systems |
US20100331762A1 (en) * | 2007-02-08 | 2010-12-30 | Neuropace, Inc. | Refillable Reservoir Lead Systems |
US7844345B2 (en) | 2007-02-08 | 2010-11-30 | Neuropace, Inc. | Drug eluting lead systems |
US8109896B2 (en) | 2008-02-11 | 2012-02-07 | Optonol Ltd. | Devices and methods for opening fluid passageways |
US20090204053A1 (en) * | 2008-02-11 | 2009-08-13 | Optonol Ltd. | Devices and methods for opening fluid passageways |
US20090281623A1 (en) * | 2008-05-12 | 2009-11-12 | Medtronic, Inc. | Customization of implantable medical devices |
US8152792B1 (en) * | 2008-09-08 | 2012-04-10 | Kornel Ezriel E | Subcutaneous drain for a body cavity |
US9393432B2 (en) | 2008-10-31 | 2016-07-19 | Medtronic, Inc. | Non-hermetic direct current interconnect |
US9173774B2 (en) | 2010-03-26 | 2015-11-03 | Optonol Ltd. | Fluid drainage device, delivery device, and associated methods of use and manufacture |
US9603644B2 (en) | 2012-08-07 | 2017-03-28 | Spinal Generations, Llc | Methods and devices for delivery of medicine to bone |
US10653470B2 (en) | 2014-02-19 | 2020-05-19 | Spinal Generation, LLC | Compressible mixing and delivery system for medical substances |
US11712278B2 (en) | 2014-02-19 | 2023-08-01 | Spinal Generations, Llc | Compressible mixing and delivery system for medical substances |
US9615863B2 (en) | 2014-10-22 | 2017-04-11 | Spinal Generations, Llc | Multichannel cannula for kyphoplasty and method of use |
US10517660B2 (en) | 2014-10-22 | 2019-12-31 | Spinal Generations, Llc | Multichannel cannula for kyphoplasty and method of use |
US11045632B2 (en) | 2017-04-24 | 2021-06-29 | Longeviti Neuro Solutions Llc | Cerebral spinal fluid shunt plug |
US11439798B2 (en) | 2017-04-24 | 2022-09-13 | Longeviti Neuro Solutions Llc | Cerebral spinal fluid shunt plug |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: AMERICAN HOSPITAL SUPPLY CORPORATION; ONE AMERICAN Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:AMERICAN HEYER- SCHULTE CORPORATION;REEL/FRAME:004099/0695 Effective date: 19830121 |