US20070161925A1 - Biopsy device with inner cutter - Google Patents

Biopsy device with inner cutter Download PDF

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Publication number
US20070161925A1
US20070161925A1 US11/714,360 US71436007A US2007161925A1 US 20070161925 A1 US20070161925 A1 US 20070161925A1 US 71436007 A US71436007 A US 71436007A US 2007161925 A1 US2007161925 A1 US 2007161925A1
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United States
Prior art keywords
tissue
inner lumen
cutter
cutting
biopsy device
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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US11/714,360
Inventor
Richard Quick
Frank Louw
Paul Lubock
Martin Shabaz
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SenoRx Inc
Original Assignee
SenoRx Inc
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Publication date
Application filed by SenoRx Inc filed Critical SenoRx Inc
Priority to US11/714,360 priority Critical patent/US20070161925A1/en
Publication of US20070161925A1 publication Critical patent/US20070161925A1/en
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/0266Pointed or sharp biopsy instruments means for severing sample
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/0266Pointed or sharp biopsy instruments means for severing sample
    • A61B10/0275Pointed or sharp biopsy instruments means for severing sample with sample notch, e.g. on the side of inner stylet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/0283Pointed or sharp biopsy instruments with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/320016Endoscopic cutting instruments, e.g. arthroscopes, resectoscopes
    • A61B17/32002Endoscopic cutting instruments, e.g. arthroscopes, resectoscopes with continuously rotating, oscillating or reciprocating cutting instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3417Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B2010/0208Biopsy devices with actuators, e.g. with triggered spring mechanisms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B2010/0225Instruments for taking cell samples or for biopsy for taking multiple samples
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/0046Surgical instruments, devices or methods, e.g. tourniquets with a releasable handle; with handle and operating part separable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/0046Surgical instruments, devices or methods, e.g. tourniquets with a releasable handle; with handle and operating part separable
    • A61B2017/00473Distal part, e.g. tip or head
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3403Needle locating or guiding means
    • A61B2017/3405Needle locating or guiding means using mechanical guide means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3417Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • A61B2017/3454Details of tips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/08Accessories or related features not otherwise provided for
    • A61B2090/0807Indication means
    • A61B2090/0811Indication means for the position of a particular part of an instrument with respect to the rest of the instrument, e.g. position of the anvil of a stapling instrument
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/30Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure
    • A61B2090/309Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure using white LEDs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/30Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39Markers, e.g. radio-opaque or breast lesions markers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/71Suction drainage systems
    • A61M1/77Suction-irrigation systems
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B23MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
    • B23QDETAILS, COMPONENTS, OR ACCESSORIES FOR MACHINE TOOLS, e.g. ARRANGEMENTS FOR COPYING OR CONTROLLING; MACHINE TOOLS IN GENERAL CHARACTERISED BY THE CONSTRUCTION OF PARTICULAR DETAILS OR COMPONENTS; COMBINATIONS OR ASSOCIATIONS OF METAL-WORKING MACHINES, NOT DIRECTED TO A PARTICULAR RESULT
    • B23Q17/00Arrangements for observing, indicating or measuring on machine tools
    • B23Q17/24Arrangements for observing, indicating or measuring on machine tools using optics or electromagnetic waves
    • B23Q17/2404Arrangements for improving direct observation of the working space, e.g. using mirrors or lamps
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F21LIGHTING
    • F21VFUNCTIONAL FEATURES OR DETAILS OF LIGHTING DEVICES OR SYSTEMS THEREOF; STRUCTURAL COMBINATIONS OF LIGHTING DEVICES WITH OTHER ARTICLES, NOT OTHERWISE PROVIDED FOR
    • F21V33/00Structural combinations of lighting devices with other articles, not otherwise provided for
    • F21V33/0064Health, life-saving or fire-fighting equipment
    • F21V33/0068Medical equipment

Definitions

  • the present invention relates generally to the field of biopsy devices and the methods of using such devices. More specifically, it relates to a device and method for accessing and removing pathologically suspect tissue from within a patient's body.
  • a biopsy in which a specimen of the suspicious tissue is removed for pathological examination and analysis.
  • the suspicious tissue is located in a subcutaneous site, such as inside a human breast.
  • a small instrument into the patient's body to access the targeted site and to extract the biopsy specimen therefrom.
  • Electrosurgical techniques have been used in a variety of biopsy procedures.
  • high frequency electrical energy is typically applied to patient tissue through an active electrode, the electrical circuit being completed by a return electrode in contact with the patent's tissue.
  • Electrical energy flowing through the tissue from the active electrode is effective to ablate tissue near the active electrode, forming an opening in the tissue and so allowing insertion of the instrument into a patient's body.
  • a return electrode may be placed on the exterior of the patient's body or may be intracorporeally disposed.
  • the return electrode is typically attached to the patient at a point remote from where the primary or active electrode contacts the tissue. However, in the case of a bipolar electrode for example, the return electrode may be disposed near to the active electrode.
  • An electrosurgical biopsy instrument is disclosed and claimed in U.S. patent application Ser. No. 09/159,467 for “Electrosurgical Biopsy Device and Method,” now U.S. Pat. No. 6,261,241, assigned to the assignee of the subject application, and which is hereby incorporated by reference in its
  • This invention is directed to biopsy devices and methods for accessing and collecting a tissue specimen that provides access to a targeted biopsy site and provides for the separation of the tissue from supporting tissue at the targeted biopsy site and the capture of the separated tissue specimen.
  • An elongated tissue biopsy device having features of the invention includes an elongated probe with an outer member having a tissue penetrating distal tip, a proximal tubular portion, an inner lumen extending within the tubular portion and an opened section in a distal portion which provides access to tissue at the targeted biopsy site.
  • the probe includes an elongated tissue-cutting member which is slidably disposed within the inner lumen of the outer member and is provided with a tissue cutting surface which is configured to sever tissue extending into the probe through an aperture.
  • the cutting surface on the tissue cutting member may be a longitudinally oriented cutting surface which is rotationally or rotationally and longitudinally moved to cut a tissue specimen or the cutting surface may be circumferentially oriented on the distal end of the cutting member which is rotationally and longitudinally moved to sever specimen tissue from supporting tissue at the targeted biopsy site.
  • the cutting member may be configured to provide longitudinal reciprocation in addition to rotation in the case of longitudinally oriented cutting surfaces and rotational reciprocation in addition to longitudinal motion in the case of circumferentially oriented cutting surfaces.
  • the cutting member has an inner lumen extending to the proximal end thereof for tissue specimen removal.
  • Mechanical withdrawal of the tissue specimen may be employed or the proximal end of the cutting member may be configured to be in fluid communication with a vacuum source to aspirate the severed tissue specimen through the inner lumen of the cutter member to a tissue collection station.
  • a fluid directing conduit may be provided in the inner lumen of the cutting member with a discharge port that is distal to the tissue specimen to deliver pressurized fluid distal to a severed tissue specimen to aid in transporting the specimen proximally through the inner lumen of the cutting member to the tissue collection station. In this manner, the mechanical withdrawal and/or the vacuum on the proximal end of the specimen and a positive pressure on the distal end of the specimen move the specimen through the inner lumen of the cutting member to a specimen collection station.
  • the probe is secured, preferably releasably secured, to a drive housing provided with at least one drive unit.
  • the tissue cutter is operatively connected to the at least one drive unit to provide the desired cutting motion.
  • the proximal end of the outer cannula is releasably secured to the drive housing so that the orientation of the outer cannula with respect to the housing can be selected before the probe is inserted into the patient.
  • the probe may be provided with a tubular tissue accessing cannula which is concentrically disposed between the outer member and the tissue cutting member and a distal portion of the accessing cannula is provided with a tissue accessing aperture.
  • the tissue accessing cannula is connected by its proximal end to a drive unit within the housing to rotate the cannula to adjust the orientation of the tissue receiving aperture about the longitudinal axis of the accessing cannula.
  • a proximal extremity of the cutting member is connected to a second drive unit or units to effect the rotation and any longitudinal motion desired for cutting the tissue specimen
  • a method of cutting and collecting a biopsy tissue specimen from a targeted biopsy site of a patient includes
  • the biopsy device may be withdrawn from the patient and the specimen removed.
  • vacuum and/or fluid pressure or mechanical devices may be sufficient to remove the tissue specimen from the patient without removal of the device from the patient's body.
  • the outer member of the probe provides the support for the probe to enable precise location of the accessing port to the desired location at the target site with its longitudinal orientation being preset before the device is introduced into the patient. If an accessing cannula is provided with the biopsy device, the accessing cannula is rotated to further position the tissue accessing aperture to the desired specimen tissue and also to relocate the accessing aperture for taking further specimens.
  • the cutting member quickly and cleanly severs the tissue specimen from the supporting tissue to provide a better tissue specimen for pathological examination.
  • FIG. 1 is an elevational view, partially in section, of an elongated tissue biopsy device having features of the invention.
  • FIG. 2 is a perspective view of the distal portion of the outer member or cannula of the biopsy device shown in the FIG. 1 .
  • FIG. 3 is a transverse view, partially in section, of the proximal end of the distal tip of the outer member shown in FIG. 2 taken along the lines 3 - 3 .
  • FIG. 4 is a perspective view of the distal portion of the tissue accessing cannula of a biopsy device shown in FIG. 1 .
  • FIG. 5 is a transverse cross-sectional view of the tissue accessing cannula shown FIG. 4 taken along the lines 5 - 5 .
  • FIG. 6 is a perspective view of the distal portion of the tissue cutter of the biopsy device shown in FIG. 1 .
  • FIG. 7 is a transverse cross-sectional view of the tissue cutter shown in FIG. 6 taken along the lines 7 - 7 .
  • FIG. 8 is a perspective view of the proximal end of the biopsy device illustrating the releasable connection between the proximal end of the probe and the housing.
  • FIGS. 9A and 9B are schematic transverse cross-sectional views of the probe shown in FIG. 1 in open and closed configurations respectively with the aperture of the tissue accessing device opening to the left.
  • FIGS. 10A and 10B are schematic transverse cross-sectional views of the probe shown in FIG. 1 in open and closed configurations respectively with the aperture of the tissue accessing device opening upwardly.
  • FIGS. 11A and 11B are schematic transverse cross-sectional views of the probe shown in FIG. 1 in open and closed configurations respectively with the aperture of the tissue accessing device opening to the right.
  • FIGS. 12A and 12B are schematic transverse cross-sectional views of the probe shown in FIG. 1 in open and closed configurations respectively with the aperture of the tissue accessing device opening downwardly.
  • FIG. 13 is a perspective view of the distal portion of an alternative design for the probe embodying features of the invention in a closed condition.
  • FIG. 14 is a top plan view of the tissue cutter of the probe shown in FIG. 13 .
  • FIG. 15 is a perspective view of the probe shown in FIG. 13 partially open.
  • FIG. 16 is a perspective view of the probe shown in FIG. 13 with the leading distal cutting edge depicted.
  • FIG. 17 is a perspective view of the probe shown in FIG. 13 further rotated from that shown in FIG. 16 .
  • FIG. 18 is a perspective view of the probe shown in FIG. 13 with the aperture of the outer member almost closed.
  • FIG. 19 is a perspective view of the distal portion of an alternative tissue cutting cannula suitable for use in the biopsy device shown in FIG. 1 .
  • FIGS. 1-7 illustrate a system 10 which includes a biopsy device 11 embodying features of the invention.
  • the biopsy device 11 generally includes an elongated shaft or probe 12 having an outer member or cannula 13 with a tissue penetrating tip 14 on the distal end thereof, a tissue accessing cannula 15 with a tissue receiving aperture 16 and a tissue-cutting member 17 with a tissue cutting surface 18 .
  • the proximal end of the outer member 13 is releasably secured to a drive housing 20 to provide a plurality of discrete orientations to the outer member 13 .
  • the housing 20 is provided with a drive unit (not shown) configured to provide motion to the tissue accessing cannula 15 and the tissue cutter 17 .
  • a tissue specimen collection station 21 is connected in a fluid flow relationship with the tissue cutter 17 through conduit 22 and is connected to a vacuum source (not shown) through conduit 23 .
  • the outer member 13 has an elongated tubular body 24 with an inner lumen 25 which is configured to receive and support the accessing cannula 15 .
  • the distal end of inner lumen 25 opens to the tissue accessing space between the distal end of the tubular body 24 and the proximal end of tissue penetrating tip 14 .
  • a connecting strut or wall portion 26 extends between the tissue penetrating distal tip 14 and the tubular body 24 of the outer member 13 .
  • the proximal end 27 of the penetrating tip 14 is provided with a first circular groove 28 which is configured to receive the distal end of the accessing cannula 15 as shown in FIGS.
  • the penetrating distal tip 14 may have a variety of tip shapes in addition to the conical shape shown and may have an arcuate RF electrode such as disclosed in U.S. Pat. No. 6,261,241, and co-pending application Ser. No. 09/477,255, filed on Jan. 4, 2000, both assigned to the present assignee.
  • the width and length of the strut 26 preferably is sufficient to provide required support to the distal tip 14 .
  • a stiffening rib may be provided to the underside of the strut for structural stiffness. Multiple struts may be used, provided that a large enough opening is available for tissue access to the aperture 16 of the accessing cannula 15 .
  • the accessing cannula 15 has a tubular body 30 which defines at least in part the tissue receiving aperture 16 .
  • the tubular body 30 has an inner lumen 31 which is configured to slidably receive the tissue cutter 17 .
  • the aperture 16 is configured to receive tissue for the specimen of suitable size.
  • the cannula 15 is configured at its proximal end to be operatively connected to a drive unit (not shown) to rotate the tubular body 30 about longitudinal axis 34 to provide a desired orientation to the aperture 16 .
  • the tissue cutter 17 is formed of tubular member 35 which has an inner lumen 36 and which has an arcuate wall portion 37 forming side cutting surface 18 .
  • the tissue cutting surface 18 may be a sharpened edge of the arcuate wall portion 37 or it may be a blade (not shown) secured to the edge.
  • the cutting surface 18 should be longer than the length of the aperture to ensure complete severance of the tissue specimen from the supporting tissue at the target site upon rotation of the cutting surface 18 .
  • the tissue cutter 17 is rotated to effect tissue cutting by cutting surface 18 , but the member may also be provided with reciprocating longitudinal movement in addition to the rotational movement thereof to provide a cleaner tissue cut. Both edges of the arcuate wall portion 37 may be sharpened or provided with blades to be cutting surfaces.
  • FIGS. 1 and 8 illustrate the releasable connection between the outer member 13 and the housing 20 to allow for a plurality of discrete orientations of the tissue receiving space of the outer member.
  • the proximal end of the tubular portion 24 of outer member 13 is provided with a plurality of longitudinally extending upstanding ribs 38 spaced about the periphery of the tubular portion 24 .
  • a corresponding number of recessed passageways 39 are disposed about the opening 40 in the distal face 41 of housing 20 designed to receive the ribs 38 .
  • Arcuate ridges 42 are provided between the ribs 38 to receive tooth 43 of releasable locking mechanism 44 provided in the interior of housing 20 .
  • the mechanism 44 for releasably locking the proximal end of the outer member 13 may take a variety of configurations.
  • the particular mechanism 44 shown in FIG. 8 is preferably manually operated by the fingers of the operating physician.
  • the operator 45 is pivotally connected within the housing 20 at an intermediate location so that downward pressure on button 46 in the top portion of the housing 20 connected to elongated member 47 presses the proximal end of operator 45 raising the distal end and the tooth 43 to release the tooth 43 from the ridge 42 to allow for movement of the proximal end of tubular portion 24 of outer member 13 with respect to the housing 20 .
  • the distal end of the mechanism 44 is biased upwardly by spring 48 so that when the proximal end of the outer member 13 is inserted into opening 40 the tooth 43 rides up ramping surface 49 on the proximal end of the ridge 42 and seats and is locked on the front face of ridge 42 .
  • the drive housing 20 and attached probe 11 allows the entire unit to be disposable.
  • the drive units within the housing control the motion of the accessing cannula 15 to orient the aperture 16 and the motion of the cutting member 17 which may be rotation or rotation and longitudinal reciprocation.
  • Other means may provide mechanical and electrical power, vacuum, and control to the probe device.
  • Examples of replaceable snap-in type drive units are disclosed in Burbank et al., U.S. patent application Ser. No. 10/179,933, “Apparatus and methods for Accessing a Body Site” hereby incorporated by reference in its entirety.
  • Drive units such as that described in WO 02/069808 (which corresponds to co-pending U.S. application Ser. No. 09/707,022, filed Nov. 6, 2000 and U.S. application Ser. No. 09/864,021, filed May 23, 2001), which are incorporated herein by reference, may be readily modified by those skilled in the art to accommodate the movement of the accessing cannula 15 and the cutting member 17 .
  • FIGS. 9A and 9B , 10 A and 11 B and 11 A and 11 B schematically illustrate the operation of the device 11 and the rotation of the probe 12 to discrete orientations.
  • This series of sketches depict the sequencing of taking tissue specimens from below or the bottom side of a target site.
  • the aperture 16 is open to the left with the arcuate wall portion 40 in a non cutting position.
  • a vacuum is applied to the inner lumen 31 of the tissue cutter 17 and tissue 50 (shown in phantom) from the target site is pulled into the interior of the accessing cannula 15 through the aperture 16 .
  • FIG. 9B the arcuate portion 37 of tissue cutter 17 is rotated to sever the aspirated tissue 50 from the supporting tissue at the target site with the cutting surface 18 .
  • the vacuum within the inner lumen 31 of the tissue cutter 17 pulls the tissue specimen through the inner lumen and into the collection station 21 shown in FIG. 1 .
  • the accessing cannula 15 is then rotated so that the aperture 16 is facing upwardly as shown in FIG. 10A and as shown in FIG. 10B the procedure for cutting the tissue specimen is repeated.
  • the aperture 16 is open to the right and the procedure is again repeated for additional specimens.
  • Other intermediate positions for the aperture 16 are possible.
  • the probe device 11 is released from the housing 20 and then is inverted or turned through 180° so that the strut 26 is on top as shown in FIGS. 12A and 12B with the aperture 16 open downwardly.
  • the housing 20 may remain in the same orientation.
  • the same motion for the accessing cannula 15 as described above may be used to obtain a similar series of tissue specimens from the top of the target site. If the target site is large enough, the probe may pass through the site and accessing may occur from within the interior of the target site in the same or similar manner as that discussed above for accessing the tissue from the top or bottom of the tissue site.
  • FIGS. 13-18 illustrate a probe 60 for a biopsy device embodying features of the invention.
  • the outer member or cannula 61 has a tissue receiving aperture 62 for receiving tissue from the target site.
  • the outer member 61 has a sharp distal tip 63 shown in phantom which is configured to easily penetrate through tissue to the target site.
  • Tissue cutter 64 is rotatably disposed within outer member 61 and has a proximal end (not shown) operatively connected to one or more drive units within housing (not shown) for imparting cutting motion thereto such as previously described .herein.
  • the inner lumen 65 of tissue cutter 64 is configured for fluid communication with a vacuum source (not shown) to urge a tissue specimen through the inner lumen 65 .
  • the tissue cutter 64 has an aperture 67 as shown in FIG. 14 defined in part by cutting edge 68 and non-cutting edge 69 .
  • the cutting surface is longitudinally oriented at an angle with respect to the longitudinal axis of the tissue cutter 64 .
  • the cutting surface or edge 68 has a distal leading cutting edge portion 70 and a proximal trailing cutting edge portion 71 .
  • This tissue cutter structure provides better application of vacuum to tissue at the target site and as a result provides better control of the tissue cutting.
  • the cutting action is shown in the sequence shown in FIGS. 13 and 15 - 18 . In FIG. 13 , the aperture 62 of the outer member 61 is closed by the arcuate wall portion 73 of tissue cutter 64 .
  • the non-cutting edge 69 of tissue cutter 64 first appears at the distal end of aperture 67 as shown in FIG. 15 .
  • Application of vacuum begins to pull tissue from the target site into the interior of the tissue cutter at the distal location.
  • the tissue cutter 64 rotates (as shown in FIGS. 16-18 ) the non-cutting edge 69 first appears to allow tissue to be pulled into the inner lumen 65 of the tissue cutter and the cutting edge 68 of the tissue cutter follows, cutting off tissue pulled into the interior of the cutter from the supporting tissue at the target site starting from the leading cutting edge portion 70 to the trailing proximal cutting edge portion 71 along the length of the aperture 67 .
  • FIG. 19 illustrates an alternative cutting member 80 which is formed of tubular member 81 and which has a sharpened distal end 82 .
  • the cutting member 80 may be advanced distally to sever tissue which has been pulled into the accessing cannula 15 through the aperture 16 .
  • the cutting member 80 may also be rotated continuously in one direction or be provided with reciprocating rotary motion in addition to the longitudinal motion to facilitate tissue cutting as shown by the arrows 83 and 84 .
  • the elongated shaft or probe of the biopsy device has a length of about 3 to about 15 cm, preferably, about 5 to about 13 cm, and more specifically, about 8 to about 9 cm for breast biopsy use.
  • the distal extremity of the various members may be provided with markers at desirable locations that provide enhanced visualization by eye, by ultrasound, by X-ray, or other imaging or visualization means.
  • An echogenic polymer coating that increases contrast resolution in ultrasound imaging devices is suitable for ultrasonic visualization.
  • Radiopaque markers may be made with, for example, stainless steel, platinum, gold, iridium, tantalum, tungsten, silver, rhodium, nickel, bismuth, other radiopaque metals, alloys and oxides of these metals.
  • the surfaces of the device in contact with tissue or other components of the device may be provided with a suitable lubricious coating such as a hydrophilic material or a fluoropolymer.
  • the outer member or cannula, the accessing cannula and the tissue cutter are preferably formed of stainless steel.
  • other high strength materials such as MP35N, other cobalt-chromium alloys, NiTi alloys, ceramics, glasses, and high strength polymeric materials or combinations thereof may be suitable.
  • a patient's skin usually must be breached in order to gain access to a body site where a tissue specimen is to be obtained.
  • a scalpel or other surgical instrument may be used to make an initial incision in the skin.
  • the biopsy device may be removed from the patient. The entire device may be removed; however, in preferred embodiments, the outer member may remain within a patient's body to aid, for example, in the acquisition of further tissue specimens and in the placement of markers at the site from which a tissue sample was taken.
  • other types of instruments may be inserted into the tissue site through the fixed outer cannula or accessing cannula in addition to or in place of the instruments described above.

Abstract

The invention is directed to devices and methods for accessing a desired target site within a patient's body and for separating and collecting a tissue specimen from the target site. The device includes a probe member or cannula with a penetrating distal tip, and a tissue cutting member which is disposed within the probe member to cut a tissue specimen from supporting tissue at the biopsy site. This probe is releasably secured to a housing to provide a plurality of discrete orientations of the probe about its longitudinal axis. Vacuum may be provided to the inner lumen of the cutting member to transport tissue through the inner lumen thereof. Rotation (and optionally longitudinal reciprocation) of the tissue cutter is effective to separate a tissue specimen from surrounding tissue at the target site. Vacuum or fluid pressure may be used to move the specimen cut from the target site proximally within the inner lumen defined at least in part by the cutting member for collection. An elongated accessing cannula having an tissue receiving aperture communicating with an inner lumen of the accessing cannula, may be provided with the device and is preferably concentrically disposed within the probe member and about the tissue cutter. The tissue cutting surface of the tissue cutter preferably is longitudinally oriented and may be at an angle with respect to the longitudinal axis of the tissue cutter.

Description

    FIELD OF THE INVENTION
  • The present invention relates generally to the field of biopsy devices and the methods of using such devices. More specifically, it relates to a device and method for accessing and removing pathologically suspect tissue from within a patient's body.
  • BACKGROUND OF THE INVENTION
  • In diagnosing and treating certain medical conditions, such as potentially cancerous tumors, it is usually desirable to perform a biopsy, in which a specimen of the suspicious tissue is removed for pathological examination and analysis. In many instances, the suspicious tissue is located in a subcutaneous site, such as inside a human breast. To minimize surgical intrusion into the patient's body, it is desirable to be able to insert a small instrument into the patient's body to access the targeted site and to extract the biopsy specimen therefrom.
  • Electrosurgical techniques have been used in a variety of biopsy procedures. In electrosurgery, high frequency electrical energy is typically applied to patient tissue through an active electrode, the electrical circuit being completed by a return electrode in contact with the patent's tissue. Electrical energy flowing through the tissue from the active electrode is effective to ablate tissue near the active electrode, forming an opening in the tissue and so allowing insertion of the instrument into a patient's body. A return electrode may be placed on the exterior of the patient's body or may be intracorporeally disposed. The return electrode is typically attached to the patient at a point remote from where the primary or active electrode contacts the tissue. However, in the case of a bipolar electrode for example, the return electrode may be disposed near to the active electrode. An electrosurgical biopsy instrument is disclosed and claimed in U.S. patent application Ser. No. 09/159,467 for “Electrosurgical Biopsy Device and Method,” now U.S. Pat. No. 6,261,241, assigned to the assignee of the subject application, and which is hereby incorporated by reference in its entirety.
  • SUMMARY OF THE INVENTION
  • This invention is directed to biopsy devices and methods for accessing and collecting a tissue specimen that provides access to a targeted biopsy site and provides for the separation of the tissue from supporting tissue at the targeted biopsy site and the capture of the separated tissue specimen.
  • An elongated tissue biopsy device having features of the invention includes an elongated probe with an outer member having a tissue penetrating distal tip, a proximal tubular portion, an inner lumen extending within the tubular portion and an opened section in a distal portion which provides access to tissue at the targeted biopsy site. The probe includes an elongated tissue-cutting member which is slidably disposed within the inner lumen of the outer member and is provided with a tissue cutting surface which is configured to sever tissue extending into the probe through an aperture. The cutting surface on the tissue cutting member may be a longitudinally oriented cutting surface which is rotationally or rotationally and longitudinally moved to cut a tissue specimen or the cutting surface may be circumferentially oriented on the distal end of the cutting member which is rotationally and longitudinally moved to sever specimen tissue from supporting tissue at the targeted biopsy site. The cutting member may be configured to provide longitudinal reciprocation in addition to rotation in the case of longitudinally oriented cutting surfaces and rotational reciprocation in addition to longitudinal motion in the case of circumferentially oriented cutting surfaces.
  • The cutting member has an inner lumen extending to the proximal end thereof for tissue specimen removal. Mechanical withdrawal of the tissue specimen may be employed or the proximal end of the cutting member may be configured to be in fluid communication with a vacuum source to aspirate the severed tissue specimen through the inner lumen of the cutter member to a tissue collection station. A fluid directing conduit may be provided in the inner lumen of the cutting member with a discharge port that is distal to the tissue specimen to deliver pressurized fluid distal to a severed tissue specimen to aid in transporting the specimen proximally through the inner lumen of the cutting member to the tissue collection station. In this manner, the mechanical withdrawal and/or the vacuum on the proximal end of the specimen and a positive pressure on the distal end of the specimen move the specimen through the inner lumen of the cutting member to a specimen collection station.
  • The probe is secured, preferably releasably secured, to a drive housing provided with at least one drive unit. The tissue cutter is operatively connected to the at least one drive unit to provide the desired cutting motion. The proximal end of the outer cannula is releasably secured to the drive housing so that the orientation of the outer cannula with respect to the housing can be selected before the probe is inserted into the patient.
  • The probe may be provided with a tubular tissue accessing cannula which is concentrically disposed between the outer member and the tissue cutting member and a distal portion of the accessing cannula is provided with a tissue accessing aperture. The tissue accessing cannula is connected by its proximal end to a drive unit within the housing to rotate the cannula to adjust the orientation of the tissue receiving aperture about the longitudinal axis of the accessing cannula. A proximal extremity of the cutting member is connected to a second drive unit or units to effect the rotation and any longitudinal motion desired for cutting the tissue specimen
  • A method of cutting and collecting a biopsy tissue specimen from a targeted biopsy site of a patient includes
      • a) advancing an elongated tissue biopsy device having features of the invention at least partially into tissue at a desired site within the patient's body with the tissue penetrating distal tip of the outer cannula distal to the tissue to be separated from the target site;
      • b) exposing the inner lumen of the accessing cannula to tissue through the accessing aperture;
      • c) applying a vacuum to the inner lumen of the accessing cannula to draw tissue into the inner lumen thereof; and
      • d) separating a tissue specimen from the target site by rotating (or rotating and longitudinally reciprocating) the tissue-cutting member to cut a tissue specimen from supporting tissue at the biopsy site which extends into the inner lumen. Vacuum may be applied to the inner lumen of the cutting member, to pull or aspirate the tissue sample proximally. In addition, or alternatively, fluid pressure may be applied to a distal portion of the inner lumen distal to the specimen to push the tissue specimen proximally or the specimen may be mechanically withdrawn. Fluid pressure may include pressure from a liquid delivered into the interior of the device, such as a physiological saline solution, and may include a gas, such as pressurized carbon dioxide, nitrogen or air, delivered into the interior of the device. The tissue specimen may then be withdrawn from the patient for subsequent pathological examination.
  • After acquisition of a tissue specimen or specimens, the biopsy device may be withdrawn from the patient and the specimen removed. However, vacuum and/or fluid pressure or mechanical devices may be sufficient to remove the tissue specimen from the patient without removal of the device from the patient's body.
  • The outer member of the probe provides the support for the probe to enable precise location of the accessing port to the desired location at the target site with its longitudinal orientation being preset before the device is introduced into the patient. If an accessing cannula is provided with the biopsy device, the accessing cannula is rotated to further position the tissue accessing aperture to the desired specimen tissue and also to relocate the accessing aperture for taking further specimens. The cutting member quickly and cleanly severs the tissue specimen from the supporting tissue to provide a better tissue specimen for pathological examination.
  • These and other advantages of the invention will become more apparent from the following detailed description of the invention and the accompanying exemplary drawings.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • FIG. 1 is an elevational view, partially in section, of an elongated tissue biopsy device having features of the invention.
  • FIG. 2 is a perspective view of the distal portion of the outer member or cannula of the biopsy device shown in the FIG. 1.
  • FIG. 3 is a transverse view, partially in section, of the proximal end of the distal tip of the outer member shown in FIG. 2 taken along the lines 3-3.
  • FIG. 4 is a perspective view of the distal portion of the tissue accessing cannula of a biopsy device shown in FIG. 1.
  • FIG. 5 is a transverse cross-sectional view of the tissue accessing cannula shown FIG. 4 taken along the lines 5-5.
  • FIG. 6 is a perspective view of the distal portion of the tissue cutter of the biopsy device shown in FIG. 1.
  • FIG. 7 is a transverse cross-sectional view of the tissue cutter shown in FIG. 6 taken along the lines 7-7.
  • FIG. 8 is a perspective view of the proximal end of the biopsy device illustrating the releasable connection between the proximal end of the probe and the housing.
  • FIGS. 9A and 9B are schematic transverse cross-sectional views of the probe shown in FIG. 1 in open and closed configurations respectively with the aperture of the tissue accessing device opening to the left.
  • FIGS. 10A and 10B are schematic transverse cross-sectional views of the probe shown in FIG. 1 in open and closed configurations respectively with the aperture of the tissue accessing device opening upwardly.
  • FIGS. 11A and 11B are schematic transverse cross-sectional views of the probe shown in FIG. 1 in open and closed configurations respectively with the aperture of the tissue accessing device opening to the right.
  • FIGS. 12A and 12B are schematic transverse cross-sectional views of the probe shown in FIG. 1 in open and closed configurations respectively with the aperture of the tissue accessing device opening downwardly.
  • FIG. 13 is a perspective view of the distal portion of an alternative design for the probe embodying features of the invention in a closed condition.
  • FIG. 14 is a top plan view of the tissue cutter of the probe shown in FIG. 13.
  • FIG. 15 is a perspective view of the probe shown in FIG. 13 partially open.
  • FIG. 16 is a perspective view of the probe shown in FIG. 13 with the leading distal cutting edge depicted.
  • FIG. 17 is a perspective view of the probe shown in FIG. 13 further rotated from that shown in FIG. 16.
  • FIG. 18 is a perspective view of the probe shown in FIG. 13 with the aperture of the outer member almost closed.
  • FIG. 19 is a perspective view of the distal portion of an alternative tissue cutting cannula suitable for use in the biopsy device shown in FIG. 1.
  • DETAILED DESCRIPTION OF THE INVENTION
  • FIGS. 1-7 illustrate a system 10 which includes a biopsy device 11 embodying features of the invention. The biopsy device 11 generally includes an elongated shaft or probe 12 having an outer member or cannula 13 with a tissue penetrating tip 14 on the distal end thereof, a tissue accessing cannula 15 with a tissue receiving aperture 16 and a tissue-cutting member 17 with a tissue cutting surface 18. The proximal end of the outer member 13 is releasably secured to a drive housing 20 to provide a plurality of discrete orientations to the outer member 13. The housing 20 is provided with a drive unit (not shown) configured to provide motion to the tissue accessing cannula 15 and the tissue cutter 17. A tissue specimen collection station 21 is connected in a fluid flow relationship with the tissue cutter 17 through conduit 22 and is connected to a vacuum source (not shown) through conduit 23.
  • As shown in more detail in FIG. 2 the outer member 13 has an elongated tubular body 24 with an inner lumen 25 which is configured to receive and support the accessing cannula 15. The distal end of inner lumen 25 opens to the tissue accessing space between the distal end of the tubular body 24 and the proximal end of tissue penetrating tip 14. A connecting strut or wall portion 26 extends between the tissue penetrating distal tip 14 and the tubular body 24 of the outer member 13. As shown in FIG. 3, the proximal end 27 of the penetrating tip 14 is provided with a first circular groove 28 which is configured to receive the distal end of the accessing cannula 15 as shown in FIGS. 1 and 3 and a second circular groove 29 which is configured to receive the distal end of tissue cutter 17. The penetrating distal tip 14 may have a variety of tip shapes in addition to the conical shape shown and may have an arcuate RF electrode such as disclosed in U.S. Pat. No. 6,261,241, and co-pending application Ser. No. 09/477,255, filed on Jan. 4, 2000, both assigned to the present assignee. The width and length of the strut 26 preferably is sufficient to provide required support to the distal tip 14. A stiffening rib may be provided to the underside of the strut for structural stiffness. Multiple struts may be used, provided that a large enough opening is available for tissue access to the aperture 16 of the accessing cannula 15.
  • As best shown in FIGS. 4 and 5, the accessing cannula 15 has a tubular body 30 which defines at least in part the tissue receiving aperture 16. The tubular body 30 has an inner lumen 31 which is configured to slidably receive the tissue cutter 17. The aperture 16 is configured to receive tissue for the specimen of suitable size. The arcuate length of the side edges 32 and 33 forming the aperture 16. The cannula 15 is configured at its proximal end to be operatively connected to a drive unit (not shown) to rotate the tubular body 30 about longitudinal axis 34 to provide a desired orientation to the aperture 16.
  • The tissue cutter 17, as depicted in FIGS. 6 and 7, is formed of tubular member 35 which has an inner lumen 36 and which has an arcuate wall portion 37 forming side cutting surface 18. The tissue cutting surface 18 may be a sharpened edge of the arcuate wall portion 37 or it may be a blade (not shown) secured to the edge. The cutting surface 18 should be longer than the length of the aperture to ensure complete severance of the tissue specimen from the supporting tissue at the target site upon rotation of the cutting surface 18. The tissue cutter 17 is rotated to effect tissue cutting by cutting surface 18, but the member may also be provided with reciprocating longitudinal movement in addition to the rotational movement thereof to provide a cleaner tissue cut. Both edges of the arcuate wall portion 37 may be sharpened or provided with blades to be cutting surfaces.
  • FIGS. 1 and 8 illustrate the releasable connection between the outer member 13 and the housing 20 to allow for a plurality of discrete orientations of the tissue receiving space of the outer member. As shown, the proximal end of the tubular portion 24 of outer member 13 is provided with a plurality of longitudinally extending upstanding ribs 38 spaced about the periphery of the tubular portion 24. A corresponding number of recessed passageways 39 are disposed about the opening 40 in the distal face 41 of housing 20 designed to receive the ribs 38. Arcuate ridges 42 are provided between the ribs 38 to receive tooth 43 of releasable locking mechanism 44 provided in the interior of housing 20. The mechanism 44 for releasably locking the proximal end of the outer member 13 may take a variety of configurations. The particular mechanism 44 shown in FIG. 8 is preferably manually operated by the fingers of the operating physician. The operator 45 is pivotally connected within the housing 20 at an intermediate location so that downward pressure on button 46 in the top portion of the housing 20 connected to elongated member 47 presses the proximal end of operator 45 raising the distal end and the tooth 43 to release the tooth 43 from the ridge 42 to allow for movement of the proximal end of tubular portion 24 of outer member 13 with respect to the housing 20. The distal end of the mechanism 44 is biased upwardly by spring 48 so that when the proximal end of the outer member 13 is inserted into opening 40 the tooth 43 rides up ramping surface 49 on the proximal end of the ridge 42 and seats and is locked on the front face of ridge 42.
  • The drive housing 20 and attached probe 11 allows the entire unit to be disposable. The drive units within the housing control the motion of the accessing cannula 15 to orient the aperture 16 and the motion of the cutting member 17 which may be rotation or rotation and longitudinal reciprocation. Other means (not shown) may provide mechanical and electrical power, vacuum, and control to the probe device. Examples of replaceable snap-in type drive units are disclosed in Burbank et al., U.S. patent application Ser. No. 10/179,933, “Apparatus and methods for Accessing a Body Site” hereby incorporated by reference in its entirety. Drive units such as that described in WO 02/069808 (which corresponds to co-pending U.S. application Ser. No. 09/707,022, filed Nov. 6, 2000 and U.S. application Ser. No. 09/864,021, filed May 23, 2001), which are incorporated herein by reference, may be readily modified by those skilled in the art to accommodate the movement of the accessing cannula 15 and the cutting member 17.
  • FIGS. 9A and 9B, 10A and 11B and 11A and 11B schematically illustrate the operation of the device 11 and the rotation of the probe 12 to discrete orientations. This series of sketches depict the sequencing of taking tissue specimens from below or the bottom side of a target site. In FIG. 9A the aperture 16 is open to the left with the arcuate wall portion 40 in a non cutting position. A vacuum is applied to the inner lumen 31 of the tissue cutter 17 and tissue 50 (shown in phantom) from the target site is pulled into the interior of the accessing cannula 15 through the aperture 16. In FIG. 9B the arcuate portion 37 of tissue cutter 17 is rotated to sever the aspirated tissue 50 from the supporting tissue at the target site with the cutting surface 18. The vacuum within the inner lumen 31 of the tissue cutter 17 pulls the tissue specimen through the inner lumen and into the collection station 21 shown in FIG. 1. The accessing cannula 15 is then rotated so that the aperture 16 is facing upwardly as shown in FIG. 10A and as shown in FIG. 10B the procedure for cutting the tissue specimen is repeated. In FIG. 11A and 11B the aperture 16 is open to the right and the procedure is again repeated for additional specimens. Other intermediate positions for the aperture 16 are possible. When the target site is accessed from the upper portion thereof, the probe device 11 is released from the housing 20 and then is inverted or turned through 180° so that the strut 26 is on top as shown in FIGS. 12A and 12B with the aperture 16 open downwardly. The housing 20, not shown in these drawings, may remain in the same orientation. The same motion for the accessing cannula 15 as described above may be used to obtain a similar series of tissue specimens from the top of the target site. If the target site is large enough, the probe may pass through the site and accessing may occur from within the interior of the target site in the same or similar manner as that discussed above for accessing the tissue from the top or bottom of the tissue site.
  • FIGS. 13-18 illustrate a probe 60 for a biopsy device embodying features of the invention. In probe 60 the outer member or cannula 61 has a tissue receiving aperture 62 for receiving tissue from the target site. The outer member 61 has a sharp distal tip 63 shown in phantom which is configured to easily penetrate through tissue to the target site. Tissue cutter 64 is rotatably disposed within outer member 61 and has a proximal end (not shown) operatively connected to one or more drive units within housing (not shown) for imparting cutting motion thereto such as previously described .herein. The inner lumen 65 of tissue cutter 64 is configured for fluid communication with a vacuum source (not shown) to urge a tissue specimen through the inner lumen 65. The tissue cutter 64 has an aperture 67 as shown in FIG. 14 defined in part by cutting edge 68 and non-cutting edge 69. The cutting surface is longitudinally oriented at an angle with respect to the longitudinal axis of the tissue cutter 64. The cutting surface or edge 68 has a distal leading cutting edge portion 70 and a proximal trailing cutting edge portion 71. This tissue cutter structure provides better application of vacuum to tissue at the target site and as a result provides better control of the tissue cutting. The cutting action is shown in the sequence shown in FIGS. 13 and 15-18. In FIG. 13, the aperture 62 of the outer member 61 is closed by the arcuate wall portion 73 of tissue cutter 64. The non-cutting edge 69 of tissue cutter 64 first appears at the distal end of aperture 67 as shown in FIG. 15. Application of vacuum begins to pull tissue from the target site into the interior of the tissue cutter at the distal location. As the tissue cutter 64 rotates (as shown in FIGS. 16-18) the non-cutting edge 69 first appears to allow tissue to be pulled into the inner lumen 65 of the tissue cutter and the cutting edge 68 of the tissue cutter follows, cutting off tissue pulled into the interior of the cutter from the supporting tissue at the target site starting from the leading cutting edge portion 70 to the trailing proximal cutting edge portion 71 along the length of the aperture 67.
  • FIG. 19 illustrates an alternative cutting member 80 which is formed of tubular member 81 and which has a sharpened distal end 82. The cutting member 80 may be advanced distally to sever tissue which has been pulled into the accessing cannula 15 through the aperture 16. The cutting member 80 may also be rotated continuously in one direction or be provided with reciprocating rotary motion in addition to the longitudinal motion to facilitate tissue cutting as shown by the arrows 83 and 84.
  • The elongated shaft or probe of the biopsy device has a length of about 3 to about 15 cm, preferably, about 5 to about 13 cm, and more specifically, about 8 to about 9 cm for breast biopsy use. To assist in properly locating the probe of the device during advancement thereof into a patient's body, (as described below), the distal extremity of the various members may be provided with markers at desirable locations that provide enhanced visualization by eye, by ultrasound, by X-ray, or other imaging or visualization means. An echogenic polymer coating that increases contrast resolution in ultrasound imaging devices (such as ECHOCOAT™ by STS Biopolymers, of Henrietta, N.Y.) is suitable for ultrasonic visualization. Radiopaque markers may be made with, for example, stainless steel, platinum, gold, iridium, tantalum, tungsten, silver, rhodium, nickel, bismuth, other radiopaque metals, alloys and oxides of these metals. In addition, the surfaces of the device in contact with tissue or other components of the device may be provided with a suitable lubricious coating such as a hydrophilic material or a fluoropolymer.
  • The outer member or cannula, the accessing cannula and the tissue cutter are preferably formed of stainless steel. However, other high strength materials such as MP35N, other cobalt-chromium alloys, NiTi alloys, ceramics, glasses, and high strength polymeric materials or combinations thereof may be suitable.
  • A patient's skin usually must be breached in order to gain access to a body site where a tissue specimen is to be obtained. A scalpel or other surgical instrument may be used to make an initial incision in the skin. After the specimens have been taken, the biopsy device may be removed from the patient. The entire device may be removed; however, in preferred embodiments, the outer member may remain within a patient's body to aid, for example, in the acquisition of further tissue specimens and in the placement of markers at the site from which a tissue sample was taken. In addition, it will be readily appreciated that other types of instruments may be inserted into the tissue site through the fixed outer cannula or accessing cannula in addition to or in place of the instruments described above.
  • While particular forms of the invention have been illustrated and described herein, it will be apparent that various modifications and improvements can be made to the invention. Moreover, individual features of embodiments of the invention may be shown in some drawings and not in others, but those skilled in the art will recognize that individual features of one embodiment of the invention can be combined with any or all the features of another embodiment. Accordingly, it is not intended that the invention be limited to the specific embodiments illustrated. It is therefore intended that this invention to be defined by the scope of the appended claims as broadly as the prior art will permit.
  • Terms such a “element”, “member”, “device”, “sections”, “portion”, “section”, “steps” and words of similar import when used herein shall not be construed as invoking the provisions of 35 U.S.C. §112(6) unless the following claims expressly use the terms “means” or “step” followed by a particular function without specific structure or action. All patents and patent applications referred to above are hereby incorporated by reference in their entirety. Accordingly, it is not intended that the invention be limited, except as by the appended claims.

Claims (27)

1-40. (canceled)
41. A tissue biopsy device for accessing and collecting a tissue specimen from a target site within a patient, comprising:
a. a housing having at least one drive unit;
b. an outer elongated tubular probe member which has an inner lumen extending therein, which has a tissue penetrating distal tip, and which has a tissue receiving aperture proximal to the penetrating distal tip in fluid communication. with the inner lumen and which has a proximal end configured to be secured to the drive housing and which has a plurality of orientations about the longitudinal axis; and
c. an elongated tissue cutter which is formed at least in part of a tubular member, which is rotatably disposed within the inner lumen of the elongated tubular probe member, which has a longitudinal axis, which has a longitudinal tissue cutting surface, which has an inner lumen extending therein for receiving tissue cut by the tissue cutting surface and which is configured for rotation within the inner lumen of the outer member to cut tissue pulled into the inner lumen of the tissue cutter.
42. The probe of claim 41 wherein the tissue cutter has a non-cutting surface which defines a tissue receiving aperture along with the tissue cutting surface.
43. The probe of claim 42 wherein the non-cutting surface of the tissue cutter is parallel with the cutting surface thereof.
44. The probe of claim 41 wherein the cutting surface of the tissue cutter has a leading distal cutting edge portion and a trailing proximal cutting edge portion.
45. An tissue biopsy device for accessing and collecting a tissue specimen from a target site within a patient, comprising:
a. a housing having at least one drive unit;
b. an elongated probe member which has a longitudinal axis, which has an inner lumen extending therein, which has a tissue penetrating distal tip, which has an open section proximal to the tissue penetrating distal tip configured to receive tissue from the target site and which has a proximal end configured to be rotatably secured to the drive housing to provide a plurality of orientations of the open section about the longitudinal axis; and
c. an elongated tissue cutter which is slidably disposed within the elongated probe member, which has a tissue cutting surface, which defines at least in part an inner lumen extending therein for receiving a tissue specimen, which is operably connected to at least one drive unit of the housing to move the tissue cutter to cut a tissue specimen from tissue extending into the open tissue receiving section of the elongated member.
46. The biopsy device of claim 45, wherein the cutting surface of the tissue cutter is longitudinally oriented.
47. The biopsy device of claim 45, wherein the cutting surface of the tissue cutter is defined at least in part by an arcuate wall section of the tissue cutter.
48. The biopsy device of claim 47 wherein the arcuate wall section of the tissue cutter has a longer arc length than the arc length of the aperture.
49. The biopsy device of claim 47, wherein the cutting surface of the tissue cutter is longer than the aperture of the elongated probe member.
50. The biopsy device of claim 45 wherein the inner lumen defined at least in part by the tissue cutter is configured to access a vacuum source to transport a tissue specimen through the inner lumen thereof to a tissue collector in fluid communication with the inner lumen.
51. The biopsy device of claim 45, wherein the tissue cutter is configured for rotational movement about a longitudinal axis.
52. The biopsy device of claim 51, wherein the tissue cutting member is also configured for reciprocating longitudinal movement.
53. The biopsy device of claim 52, wherein the tissue cutter is configured for reciprocating longitudinal movement of between about 0.01 inch and about 0.1 inch.
54. The biopsy device of claim 47, wherein the arcuate wall section of the tissue cutter has longitudinally oriented cutting surfaces along both edges.
55. The biopsy device of claim 45 wherein the cutting surface of the tissue cutter is longitudinally oriented at an angle with respect to the longitudinal axis of the tissue cutter.
56. The biopsy device of claim 47 wherein the cutting surface of the tissue cutter has a leading distal cutting edge portion and a trailing proximal cutting edge portion.
57. The biopsy device of claim 47 wherein the tissue cutter has a non-cutting surface which extends parallel with the cutting surface.
58. The biopsy device of claim 57 wherein the cutting and non-cutting surfaces of the tissue cutter define in part a tissue receiving aperture.
59. The biopsy device of claim 45, wherein the tissue cutter is configured for longitudinal movement along a longitudinal axis.
60. The biopsy device of claim 59, wherein the tissue cutting member is also configured for reciprocating rotational movement.
61. The biopsy device of claim 45 wherein the drive housing which has a plurality of drive units.
62. The biopsy device of claim 45 wherein the elongated probe member is releasably secured to the drive housing
63. A method of separating a biopsy tissue specimen from supporting tissue at a target site within a patient's body, comprising:
a. providing a biopsy device comprising:
i. a drive housing having at least one drive member;
ii. an elongated probe member which is rotatably secured to the drive housing, which has an inner lumen extending therein, which has a tissue penetrating distal tip, which has an open section proximal to the tissue penetrating distal tip; and
iii. an elongated tissue cutting member which is formed at least in part of a tubular member, which is slidably disposed within the inner lumen of the elongated probe member, which has at least one tissue cutting surface, which has an inner lumen extending therein for receiving tissue cut by the tissue cutting surface, and which is connected to a drive unit of the elongated probe member to move the tissue cutter within the inner lumen of the elongated probe member;
b. advancing the elongated probe member at least partially into or adjacent to tissue at the target site;
c. exposing the tissue receiving aperture of the elongated probe member to tissue at the tissue site;
d. applying a vacuum to the inner lumen of the tissue cutting member to draw tissue from the tissue site into the inner lumen of the elongated probe member;
e. moving the tissue cutting member within the inner lumen of the elongated probe member by operating the drive member within the elongated probe member to cut tissue drawn into the inner lumen from supporting tissue at the tissue site; and
f. transporting cut tissue through the inner lumen of the tissue cutter.
64. The method of claim 63, wherein the tissue cutting member is moved longitudinally and rotated to cut tissue.
65. The method of claim 64, wherein the longitudinal movement of the tissue cutting member is reciprocating movement.
66. The method of claim 63, wherein pressurized fluid is provided within the inner lumen of the tissue cutting member distal to a tissue specimen therein to transport the tissue specimen proximally within the inner lumen of the tissue cutting member.
US11/714,360 2003-02-24 2007-03-06 Biopsy device with inner cutter Abandoned US20070161925A1 (en)

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US11/714,360 US20070161925A1 (en) 2003-02-24 2007-03-06 Biopsy device with inner cutter

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US10/374,915 US7189206B2 (en) 2003-02-24 2003-02-24 Biopsy device with inner cutter
US11/714,360 US20070161925A1 (en) 2003-02-24 2007-03-06 Biopsy device with inner cutter

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US10/374,915 Expired - Lifetime US7189206B2 (en) 1999-02-02 2003-02-24 Biopsy device with inner cutter
US10/642,406 Active 2025-04-18 US7819819B2 (en) 1999-02-02 2003-08-15 Biopsy device with inner cutting member
US11/714,360 Abandoned US20070161925A1 (en) 2003-02-24 2007-03-06 Biopsy device with inner cutter
US12/229,545 Active 2025-10-25 US9044215B2 (en) 2003-02-24 2008-08-25 Biopsy device with selectable tissue receiving aperature orientation and site illumination
US12/229,553 Active 2024-04-22 US10172595B2 (en) 2003-02-24 2008-08-25 Biopsy device with selectable tissue receiving aperture orientation and site illumination
US12/793,465 Expired - Lifetime US8460204B2 (en) 2003-02-24 2010-06-03 Biopsy device with inner cutting member
US12/794,480 Expired - Fee Related US9204866B2 (en) 2003-02-24 2010-06-04 Biopsy device with selectable tissue receiving aperture orientation and site illumination
US13/749,241 Expired - Lifetime US10231715B2 (en) 2003-02-24 2013-01-24 Biopsy device with inner cutting member
US14/700,574 Active 2024-10-17 US10335127B2 (en) 2003-02-24 2015-04-30 Biopsy device with selectable tissue receiving aperature orientation and site illumination
US16/239,629 Active 2025-07-25 US11534147B2 (en) 2003-02-24 2019-01-04 Biopsy device with a removable sample recieving cartridge

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US10/642,406 Active 2025-04-18 US7819819B2 (en) 1999-02-02 2003-08-15 Biopsy device with inner cutting member

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US12/229,545 Active 2025-10-25 US9044215B2 (en) 2003-02-24 2008-08-25 Biopsy device with selectable tissue receiving aperature orientation and site illumination
US12/229,553 Active 2024-04-22 US10172595B2 (en) 2003-02-24 2008-08-25 Biopsy device with selectable tissue receiving aperture orientation and site illumination
US12/793,465 Expired - Lifetime US8460204B2 (en) 2003-02-24 2010-06-03 Biopsy device with inner cutting member
US12/794,480 Expired - Fee Related US9204866B2 (en) 2003-02-24 2010-06-04 Biopsy device with selectable tissue receiving aperture orientation and site illumination
US13/749,241 Expired - Lifetime US10231715B2 (en) 2003-02-24 2013-01-24 Biopsy device with inner cutting member
US14/700,574 Active 2024-10-17 US10335127B2 (en) 2003-02-24 2015-04-30 Biopsy device with selectable tissue receiving aperature orientation and site illumination
US16/239,629 Active 2025-07-25 US11534147B2 (en) 2003-02-24 2019-01-04 Biopsy device with a removable sample recieving cartridge

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Cited By (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070060935A1 (en) * 2005-07-11 2007-03-15 Schwardt Jeffrey D Apparatus and methods of tissue removal within a spine
US20090270892A1 (en) * 2008-04-25 2009-10-29 Greg Arcenio Steerable medical device for tissue disruption
US20090270862A1 (en) * 2008-04-25 2009-10-29 Greg Arcenio Medical device with one-way rotary drive mechanism
US20090270893A1 (en) * 2008-04-25 2009-10-29 Greg Arcenio Medical device for tissue disruption with serrated expandable portion
US20100030216A1 (en) * 2008-07-30 2010-02-04 Arcenio Gregory B Discectomy tool having counter-rotating nucleus disruptors
USD640977S1 (en) 2009-09-25 2011-07-05 C. R. Bard, Inc. Charging station for a battery operated biopsy device
US8002713B2 (en) 2002-03-19 2011-08-23 C. R. Bard, Inc. Biopsy device and insertable biopsy needle module
US8012102B2 (en) 2005-01-31 2011-09-06 C. R. Bard, Inc. Quick cycle biopsy system
US8016772B2 (en) 2002-03-19 2011-09-13 C. R. Bard, Inc. Biopsy device for removing tissue specimens using a vacuum
US8052615B2 (en) 2004-07-09 2011-11-08 Bard Peripheral Vascular, Inc. Length detection system for biopsy device
US8162851B2 (en) 2003-03-29 2012-04-24 C. R. Bard, Inc. Biopsy needle system having a pressure generating unit
US20120130274A1 (en) * 2010-11-19 2012-05-24 Jean-Charles Persat Tissue sampling tool, in particular for adipose tissue
US8251917B2 (en) 2006-08-21 2012-08-28 C. R. Bard, Inc. Self-contained handheld biopsy needle
US8262585B2 (en) 2005-08-10 2012-09-11 C. R. Bard, Inc. Single-insertion, multiple sampling biopsy device with linear drive
US8262586B2 (en) 2006-10-24 2012-09-11 C. R. Bard, Inc. Large sample low aspect ratio biopsy needle
US8267868B2 (en) 2005-08-10 2012-09-18 C. R. Bard, Inc. Single-insertion, multiple sample biopsy device with integrated markers
US20120245487A1 (en) * 2011-03-24 2012-09-27 Robert Eells Closed side-sampling biopsy device
US8282574B2 (en) 2005-08-10 2012-10-09 C. R. Bard, Inc. Single-insertion, multiple sampling biopsy device usable with various transport systems and integrated markers
US8430824B2 (en) 2009-10-29 2013-04-30 Bard Peripheral Vascular, Inc. Biopsy driver assembly having a control circuit for conserving battery power
US8454532B2 (en) 2007-12-27 2013-06-04 Devicor Medical Products, Inc. Clutch and valving system for tetherless biopsy device
US8485987B2 (en) 2006-10-06 2013-07-16 Bard Peripheral Vascular, Inc. Tissue handling system with reduced operator exposure
US8485989B2 (en) 2009-09-01 2013-07-16 Bard Peripheral Vascular, Inc. Biopsy apparatus having a tissue sample retrieval mechanism
US8597206B2 (en) 2009-10-12 2013-12-03 Bard Peripheral Vascular, Inc. Biopsy probe assembly having a mechanism to prevent misalignment of components prior to installation
US8690793B2 (en) 2009-03-16 2014-04-08 C. R. Bard, Inc. Biopsy device having rotational cutting
US8708928B2 (en) 2009-04-15 2014-04-29 Bard Peripheral Vascular, Inc. Biopsy apparatus having integrated fluid management
US8845548B2 (en) 2009-06-12 2014-09-30 Devicor Medical Products, Inc. Cutter drive assembly for biopsy device
US8858463B2 (en) 2007-12-20 2014-10-14 C. R. Bard, Inc. Biopsy device
US9173641B2 (en) 2009-08-12 2015-11-03 C. R. Bard, Inc. Biopsy apparatus having integrated thumbwheel mechanism for manual rotation of biopsy cannula
WO2017023674A1 (en) * 2015-07-31 2017-02-09 Polygon Medical, Inc. Polypectomy systems, devices, and methods
US9943293B2 (en) 2011-11-09 2018-04-17 Teesuvac Aps Handheld tissue sample extraction device
USD847992S1 (en) 2017-06-27 2019-05-07 Polygon Medical, Inc. Medical device handle
US10285731B2 (en) 2017-06-14 2019-05-14 Polygon Medical, Inc. Polypectomy systems, devices, and methods
US10285673B2 (en) 2013-03-20 2019-05-14 Bard Peripheral Vascular, Inc. Biopsy device
US10456120B2 (en) 2013-11-05 2019-10-29 C. R. Bard, Inc. Biopsy device having integrated vacuum
US10463350B2 (en) 2015-05-01 2019-11-05 C. R. Bard, Inc. Biopsy device
US11116483B2 (en) 2017-05-19 2021-09-14 Merit Medical Systems, Inc. Rotating biopsy needle
US11793498B2 (en) 2017-05-19 2023-10-24 Merit Medical Systems, Inc. Biopsy needle devices and methods of use
US11844500B2 (en) 2017-05-19 2023-12-19 Merit Medical Systems, Inc. Semi-automatic biopsy needle device and methods of use

Families Citing this family (302)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8668737B2 (en) 1997-10-10 2014-03-11 Senorx, Inc. Tissue marking implant
US8498693B2 (en) 1999-02-02 2013-07-30 Senorx, Inc. Intracorporeal marker and marker delivery device
US8282573B2 (en) 2003-02-24 2012-10-09 Senorx, Inc. Biopsy device with selectable tissue receiving aperture orientation and site illumination
US7189206B2 (en) * 2003-02-24 2007-03-13 Senorx, Inc. Biopsy device with inner cutter
US7983734B2 (en) 2003-05-23 2011-07-19 Senorx, Inc. Fibrous marker and intracorporeal delivery thereof
US6862470B2 (en) 1999-02-02 2005-03-01 Senorx, Inc. Cavity-filling biopsy site markers
US8361082B2 (en) 1999-02-02 2013-01-29 Senorx, Inc. Marker delivery device with releasable plug
US11229472B2 (en) 2001-06-12 2022-01-25 Cilag Gmbh International Modular battery powered handheld surgical instrument with multiple magnetic position sensors
GB0120645D0 (en) 2001-08-24 2001-10-17 Smiths Group Plc Medico-surgical devices
US20050277918A1 (en) * 2003-03-07 2005-12-15 Baylis Medical Company Inc. Electrosurgical cannula
US10973545B2 (en) 2002-05-31 2021-04-13 Teleflex Life Sciences Limited Powered drivers, intraosseous devices and methods to access bone marrow
US11298202B2 (en) 2002-05-31 2022-04-12 Teleflex Life Sciences Limited Biopsy devices and related methods
US9545243B2 (en) * 2002-05-31 2017-01-17 Vidacare LLC Bone marrow aspiration devices and related methods
US11337728B2 (en) 2002-05-31 2022-05-24 Teleflex Life Sciences Limited Powered drivers, intraosseous devices and methods to access bone marrow
EP3292821A1 (en) 2002-05-31 2018-03-14 Vidacare LLC Apparatus and method to access bone marrow
US8668698B2 (en) 2002-05-31 2014-03-11 Vidacare Corporation Assembly for coupling powered driver with intraosseous device
US8641715B2 (en) 2002-05-31 2014-02-04 Vidacare Corporation Manual intraosseous device
US20060036158A1 (en) 2003-11-17 2006-02-16 Inrad, Inc. Self-contained, self-piercing, side-expelling marking apparatus
GB0307350D0 (en) 2003-03-29 2003-05-07 Smiths Group Plc Catheters
DE20305093U1 (en) 2003-03-29 2003-09-11 Heske Norbert F Coaxial cannula with sealing element
US7877133B2 (en) 2003-05-23 2011-01-25 Senorx, Inc. Marker or filler forming fluid
US9504477B2 (en) 2003-05-30 2016-11-29 Vidacare LLC Powered driver
US9408592B2 (en) * 2003-12-23 2016-08-09 Senorx, Inc. Biopsy device with aperture orientation and improved tip
US7297141B2 (en) * 2004-01-20 2007-11-20 Ethicon Endo-Surgery, Inc. Method for accessing an operative space
US8182501B2 (en) 2004-02-27 2012-05-22 Ethicon Endo-Surgery, Inc. Ultrasonic surgical shears and method for sealing a blood vessel using same
US20050203441A1 (en) * 2004-03-12 2005-09-15 Voegele James W. Electrode sleeve for biopsy device
US20050256426A1 (en) * 2004-05-12 2005-11-17 William Brugge Apparatus and method for collecting tissue samples
US20070198019A1 (en) * 2004-07-29 2007-08-23 X-Sten Corp. Spinal ligament modification devices
US7740594B2 (en) * 2004-09-29 2010-06-22 Ethicon Endo-Surgery, Inc. Cutter for biopsy device
US20060074345A1 (en) * 2004-09-29 2006-04-06 Hibner John A Biopsy apparatus and method
US7276032B2 (en) * 2004-09-29 2007-10-02 Ethicon Endo-Surgery, Inc. Biopsy apparatus and method
US7740596B2 (en) 2004-09-29 2010-06-22 Ethicon Endo-Surgery, Inc. Biopsy device with sample storage
US20060074344A1 (en) * 2004-09-29 2006-04-06 Hibner John A Fluid control for biopsy device
BRPI0518171B8 (en) 2004-10-08 2021-06-22 Ethicon Endo Surgery Inc ultrasonic forceps coagulator apparatus
US8343071B2 (en) * 2004-12-16 2013-01-01 Senorx, Inc. Biopsy device with aperture orientation and improved tip
US10357328B2 (en) 2005-04-20 2019-07-23 Bard Peripheral Vascular, Inc. and Bard Shannon Limited Marking device with retractable cannula
US9095325B2 (en) * 2005-05-23 2015-08-04 Senorx, Inc. Tissue cutting member for a biopsy device
WO2007008710A2 (en) * 2005-07-11 2007-01-18 Kyphon Inc. Apparatus and methods of tissue removal within a spine
US20070149990A1 (en) * 2005-07-11 2007-06-28 Palmer Erika I Apparatus and methods of tissue removal within a spine
US20070055263A1 (en) * 2005-07-29 2007-03-08 X-Sten Corp. Tools for Percutaneous Spinal Ligament Decompression and Device for Supporting Same
WO2007016683A2 (en) 2005-07-29 2007-02-08 X-Sten, Corp. Device for resecting spinal tissue
US7572236B2 (en) 2005-08-05 2009-08-11 Senorx, Inc. Biopsy device with fluid delivery to tissue specimens
US8317725B2 (en) * 2005-08-05 2012-11-27 Senorx, Inc. Biopsy device with fluid delivery to tissue specimens
US7867173B2 (en) 2005-08-05 2011-01-11 Devicor Medical Products, Inc. Biopsy device with replaceable probe and incorporating vibration insertion assist and static vacuum source sample stacking retrieval
USRE46135E1 (en) 2005-08-05 2016-09-06 Devicor Medical Products, Inc. Vacuum syringe assisted biopsy device
US7854707B2 (en) 2005-08-05 2010-12-21 Devicor Medical Products, Inc. Tissue sample revolver drum biopsy device
US20070191713A1 (en) 2005-10-14 2007-08-16 Eichmann Stephen E Ultrasonic device for cutting and coagulating
US7621930B2 (en) 2006-01-20 2009-11-24 Ethicon Endo-Surgery, Inc. Ultrasound medical instrument having a medical ultrasonic blade
US7670299B2 (en) * 2006-03-07 2010-03-02 Ethincon Endo-Surgery, Inc. Device for minimally invasive internal tissue removal
US7806834B2 (en) * 2006-03-07 2010-10-05 Devicor Medical Products, Inc. Device for minimally invasive internal tissue removal
US8036185B2 (en) * 2006-04-28 2011-10-11 Symbol Technologies, Inc. Methods and apparatus for a consolidated switch for use with networked RF components
US7942830B2 (en) 2006-05-09 2011-05-17 Vertos Medical, Inc. Ipsilateral approach to minimally invasive ligament decompression procedure
WO2007134370A1 (en) * 2006-05-18 2007-11-29 Bhc Pharmaceuticals Pty Ltd Cannula for performing aspiration of tissue further comprising imaging device or distal cutter
US8394033B2 (en) * 2006-07-12 2013-03-12 Boston Scientific Scimed, Inc. Biopsy device
US8377005B2 (en) * 2006-09-11 2013-02-19 Custom Medical Applications Neural injection system and related methods
US8449503B2 (en) 2010-11-30 2013-05-28 Custom Medical Applications Neural injection system and related methods
US9888940B2 (en) 2006-09-11 2018-02-13 Custom Medical Applications Neural injection system and related methods
US7857788B2 (en) * 2006-09-11 2010-12-28 Custom Medical Applications Neural injection system and related methods
CN104814768B (en) 2006-09-12 2018-04-13 维达保健有限责任公司 Medical procedures trays and correlation technique
US8944069B2 (en) 2006-09-12 2015-02-03 Vidacare Corporation Assemblies for coupling intraosseous (IO) devices to powered drivers
US8694077B2 (en) * 2006-10-06 2014-04-08 The Cleveland Clinic Foundation Apparatus and method for targeting a body tissue
US8647349B2 (en) 2006-10-18 2014-02-11 Hologic, Inc. Systems for performing gynecological procedures with mechanical distension
US8025656B2 (en) 2006-11-07 2011-09-27 Hologic, Inc. Methods, systems and devices for performing gynecological procedures
US9392935B2 (en) * 2006-11-07 2016-07-19 Hologic, Inc. Methods for performing a medical procedure
US7456107B2 (en) * 2006-11-09 2008-11-25 Cabot Microelectronics Corporation Compositions and methods for CMP of low-k-dielectric materials
US9579077B2 (en) 2006-12-12 2017-02-28 C.R. Bard, Inc. Multiple imaging mode tissue marker
US20140039343A1 (en) 2006-12-13 2014-02-06 Devicor Medical Products, Inc. Biopsy system
US8702623B2 (en) 2008-12-18 2014-04-22 Devicor Medical Products, Inc. Biopsy device with discrete tissue chambers
US9345457B2 (en) 2006-12-13 2016-05-24 Devicor Medical Products, Inc. Presentation of biopsy sample by biopsy device
US8480595B2 (en) 2006-12-13 2013-07-09 Devicor Medical Products, Inc. Biopsy device with motorized needle cocking
US8401622B2 (en) 2006-12-18 2013-03-19 C. R. Bard, Inc. Biopsy marker with in situ-generated imaging properties
US20080221605A1 (en) 2007-01-26 2008-09-11 Laurimed Llc Cutting device positioned via control wire to perform selective discectomy
WO2008100906A2 (en) * 2007-02-12 2008-08-21 Vertos Medical, Inc. Tissue excision devices and methods
US8142461B2 (en) 2007-03-22 2012-03-27 Ethicon Endo-Surgery, Inc. Surgical instruments
US8226675B2 (en) 2007-03-22 2012-07-24 Ethicon Endo-Surgery, Inc. Surgical instruments
US8911460B2 (en) 2007-03-22 2014-12-16 Ethicon Endo-Surgery, Inc. Ultrasonic surgical instruments
US8057498B2 (en) 2007-11-30 2011-11-15 Ethicon Endo-Surgery, Inc. Ultrasonic surgical instrument blades
US9095366B2 (en) 2007-04-06 2015-08-04 Hologic, Inc. Tissue cutter with differential hardness
US20090270898A1 (en) 2007-04-06 2009-10-29 Interlace Medical, Inc. Tissue removal device with high reciprocation rate
US9259233B2 (en) 2007-04-06 2016-02-16 Hologic, Inc. Method and device for distending a gynecological cavity
EP2134283B1 (en) * 2007-04-06 2014-06-11 Hologic, Inc. System and device for tissue removal
US8137320B2 (en) 2007-05-01 2012-03-20 Suros Surgical Systems, Inc. Securement for a surgical site marker and deployment device for same
US8523889B2 (en) 2007-07-27 2013-09-03 Ethicon Endo-Surgery, Inc. Ultrasonic end effectors with increased active length
US8808319B2 (en) 2007-07-27 2014-08-19 Ethicon Endo-Surgery, Inc. Surgical instruments
US8882791B2 (en) 2007-07-27 2014-11-11 Ethicon Endo-Surgery, Inc. Ultrasonic surgical instruments
US8430898B2 (en) 2007-07-31 2013-04-30 Ethicon Endo-Surgery, Inc. Ultrasonic surgical instruments
US9044261B2 (en) 2007-07-31 2015-06-02 Ethicon Endo-Surgery, Inc. Temperature controlled ultrasonic surgical instruments
US8512365B2 (en) 2007-07-31 2013-08-20 Ethicon Endo-Surgery, Inc. Surgical instruments
EP2796102B1 (en) 2007-10-05 2018-03-14 Ethicon LLC Ergonomic surgical instruments
EP2205170A2 (en) * 2007-10-31 2010-07-14 Stanley I. Kim Rotating biopsy device and biopsy robot
US20090118709A1 (en) * 2007-11-06 2009-05-07 Vertos Medical, Inc. A Delaware Corporation Tissue Excision Tool, Kits and Methods of Using the Same
US10010339B2 (en) 2007-11-30 2018-07-03 Ethicon Llc Ultrasonic surgical blades
US20090209853A1 (en) * 2008-02-19 2009-08-20 Parihar Shailendra K Biopsy site marker applier
WO2009124192A1 (en) 2008-04-02 2009-10-08 Laurimed, Llc Methods and devices for delivering injections
US9089360B2 (en) 2008-08-06 2015-07-28 Ethicon Endo-Surgery, Inc. Devices and techniques for cutting and coagulating tissue
US8058771B2 (en) 2008-08-06 2011-11-15 Ethicon Endo-Surgery, Inc. Ultrasonic device for cutting and coagulating with stepped output
EP2326253B1 (en) * 2008-08-18 2016-11-23 The Brigham and Women's Hospital, Inc. Integrated surgical sampling probe
US9327061B2 (en) 2008-09-23 2016-05-03 Senorx, Inc. Porous bioabsorbable implant
US9186128B2 (en) 2008-10-01 2015-11-17 Covidien Lp Needle biopsy device
US8968210B2 (en) 2008-10-01 2015-03-03 Covidien LLP Device for needle biopsy with integrated needle protection
US9332973B2 (en) 2008-10-01 2016-05-10 Covidien Lp Needle biopsy device with exchangeable needle and integrated needle protection
US9782565B2 (en) 2008-10-01 2017-10-10 Covidien Lp Endoscopic ultrasound-guided biliary access system
US11298113B2 (en) 2008-10-01 2022-04-12 Covidien Lp Device for needle biopsy with integrated needle protection
USD619253S1 (en) 2008-10-23 2010-07-06 Vertos Medical, Inc. Tissue modification device
USD611146S1 (en) 2008-10-23 2010-03-02 Vertos Medical, Inc. Tissue modification device
USD610259S1 (en) 2008-10-23 2010-02-16 Vertos Medical, Inc. Tissue modification device
USD635671S1 (en) 2008-10-23 2011-04-05 Vertos Medical, Inc. Tissue modification device
USD619252S1 (en) 2008-10-23 2010-07-06 Vertos Medical, Inc. Tissue modification device
USD621939S1 (en) 2008-10-23 2010-08-17 Vertos Medical, Inc. Tissue modification device
US8771305B2 (en) * 2008-11-11 2014-07-08 Edgar Louis Shriver Lateral intravascular excision/incision devices
US7846109B2 (en) * 2008-12-18 2010-12-07 Devicor Medical Products, Inc. Biopsy device with sliding cutter cover
US8167815B2 (en) * 2008-12-18 2012-05-01 Devicor Medical Products, Inc. Biopsy device with retractable cutter
US7862518B2 (en) * 2008-12-18 2011-01-04 Devicor Medical Products, Inc. Biopsy device with telescoping cutter cover
US8366635B2 (en) 2008-12-18 2013-02-05 Devicor Medical Products, Inc. Biopsy probe and targeting set interface
US20100160822A1 (en) * 2008-12-18 2010-06-24 Parihar Shailendra K Biopsy Device with Detachable Needle
BRPI0823399B8 (en) 2008-12-30 2021-06-22 Bard Inc C R marker release device for tissue marker positioning
DE102009010561A1 (en) * 2009-02-16 2010-08-19 Karl Storz Gmbh & Co. Kg Medical instrument for cutting tissue
US11903602B2 (en) 2009-04-29 2024-02-20 Hologic, Inc. Uterine fibroid tissue removal device
US9700339B2 (en) 2009-05-20 2017-07-11 Ethicon Endo-Surgery, Inc. Coupling arrangements and methods for attaching tools to ultrasonic surgical instruments
US8334635B2 (en) 2009-06-24 2012-12-18 Ethicon Endo-Surgery, Inc. Transducer arrangements for ultrasonic surgical instruments
US9386942B2 (en) * 2009-06-26 2016-07-12 Cianna Medical, Inc. Apparatus, systems, and methods for localizing markers or tissue structures within a body
US8461744B2 (en) 2009-07-15 2013-06-11 Ethicon Endo-Surgery, Inc. Rotating transducer mount for ultrasonic surgical instruments
US8663220B2 (en) 2009-07-15 2014-03-04 Ethicon Endo-Surgery, Inc. Ultrasonic surgical instruments
US9072506B1 (en) 2009-09-02 2015-07-07 C. R. Bard, Inc. Biopsy apparatus including a biopsy device having a sample receiving notch with a tissue anchor
US10441345B2 (en) 2009-10-09 2019-10-15 Ethicon Llc Surgical generator for ultrasonic and electrosurgical devices
US11090104B2 (en) 2009-10-09 2021-08-17 Cilag Gmbh International Surgical generator for ultrasonic and electrosurgical devices
US9168054B2 (en) 2009-10-09 2015-10-27 Ethicon Endo-Surgery, Inc. Surgical generator for ultrasonic and electrosurgical devices
US8986302B2 (en) 2009-10-09 2015-03-24 Ethicon Endo-Surgery, Inc. Surgical generator for ultrasonic and electrosurgical devices
USRE47996E1 (en) 2009-10-09 2020-05-19 Ethicon Llc Surgical generator for ultrasonic and electrosurgical devices
US8298157B2 (en) * 2009-12-15 2012-10-30 C. R. Bard, Inc. Introducer cannula having a tissue anchor for use with a medical instrument
US8480592B2 (en) 2009-12-23 2013-07-09 C. R. Bard, Inc. Biopsy probe mechanism having multiple echogenic features
US8469981B2 (en) 2010-02-11 2013-06-25 Ethicon Endo-Surgery, Inc. Rotatable cutting implement arrangements for ultrasonic surgical instruments
US8951272B2 (en) 2010-02-11 2015-02-10 Ethicon Endo-Surgery, Inc. Seal arrangements for ultrasonically powered surgical instruments
US8961547B2 (en) 2010-02-11 2015-02-24 Ethicon Endo-Surgery, Inc. Ultrasonic surgical instruments with moving cutting implement
US8486096B2 (en) 2010-02-11 2013-07-16 Ethicon Endo-Surgery, Inc. Dual purpose surgical instrument for cutting and coagulating tissue
US8579928B2 (en) 2010-02-11 2013-11-12 Ethicon Endo-Surgery, Inc. Outer sheath and blade arrangements for ultrasonic surgical instruments
US9259234B2 (en) 2010-02-11 2016-02-16 Ethicon Endo-Surgery, Llc Ultrasonic surgical instruments with rotatable blade and hollow sheath arrangements
US9237883B2 (en) * 2010-02-25 2016-01-19 JJ Dogs LLC Full core biopsy device
US20110237975A1 (en) 2010-03-24 2011-09-29 United States Endoscopy Group, Inc. Multiple biopsy device
US8409235B2 (en) * 2010-04-30 2013-04-02 Medtronic Xomed, Inc. Rotary cutting tool with improved cutting and reduced clogging on soft tissue and thin bone
GB2480498A (en) 2010-05-21 2011-11-23 Ethicon Endo Surgery Inc Medical device comprising RF circuitry
US8685052B2 (en) 2010-06-30 2014-04-01 Laurimed, Llc Devices and methods for cutting tissue
ES2545816T3 (en) 2010-06-30 2015-09-16 Laurimed, Llc Tissue cutting and evacuation devices
US8790362B1 (en) * 2010-07-16 2014-07-29 Greatbatch Ltd. Catheter for positioning a lead in the vasculature
US8795327B2 (en) 2010-07-22 2014-08-05 Ethicon Endo-Surgery, Inc. Electrosurgical instrument with separate closure and cutting members
US9192431B2 (en) 2010-07-23 2015-11-24 Ethicon Endo-Surgery, Inc. Electrosurgical cutting and sealing instrument
US9220485B2 (en) 2010-08-28 2015-12-29 Endochoice, Inc. Tissue collection and separation device
JP2013542002A (en) * 2010-09-29 2013-11-21 サウンド サージカル テクノロジーズ エルエルシー Fat removing device and fat removing method
EP2645937A4 (en) * 2010-12-03 2014-06-25 Barrostat Medical Inc Methods and devices for metabolic surgery
US8512326B2 (en) * 2011-06-24 2013-08-20 Arqos Surgical, Inc. Tissue extraction devices and methods
WO2012178119A2 (en) 2011-06-24 2012-12-27 Arqos Surgical, Inc. Tissue extraction devices and methods
US9737362B2 (en) 2011-07-06 2017-08-22 Boston Scientific Scimed, Inc. Tissue cutting systems and methods
US9259265B2 (en) 2011-07-22 2016-02-16 Ethicon Endo-Surgery, Llc Surgical instruments for tensioning tissue
EP2744418B1 (en) 2011-08-18 2016-01-06 Hologic, Inc. Tissue removal system
US9084847B2 (en) 2011-09-22 2015-07-21 Iogyn, Inc. Surgical fluid management systems and methods
US9597149B2 (en) 2011-11-04 2017-03-21 Iogyn, Inc. Tissue extraction devices and methods
US9439677B2 (en) 2012-01-20 2016-09-13 Iogyn, Inc. Medical device and methods
EP2811932B1 (en) 2012-02-10 2019-06-26 Ethicon LLC Robotically controlled surgical instrument
WO2013119336A1 (en) 2012-02-10 2013-08-15 Laurimed, Llc Vacuum powered rotary devices and methods
US9226766B2 (en) 2012-04-09 2016-01-05 Ethicon Endo-Surgery, Inc. Serial communication protocol for medical device
US9724118B2 (en) 2012-04-09 2017-08-08 Ethicon Endo-Surgery, Llc Techniques for cutting and coagulating tissue for ultrasonic surgical instruments
US9237921B2 (en) 2012-04-09 2016-01-19 Ethicon Endo-Surgery, Inc. Devices and techniques for cutting and coagulating tissue
US9241731B2 (en) 2012-04-09 2016-01-26 Ethicon Endo-Surgery, Inc. Rotatable electrical connection for ultrasonic surgical instruments
US9439668B2 (en) 2012-04-09 2016-09-13 Ethicon Endo-Surgery, Llc Switch arrangements for ultrasonic surgical instruments
EP2838435B1 (en) 2012-04-16 2020-03-25 Hathaway, Jeff M. Biopsy device
US9226792B2 (en) 2012-06-12 2016-01-05 Medtronic Advanced Energy Llc Debridement device and method
EP2861157B1 (en) * 2012-06-14 2018-08-15 Sanoculis Ltd. Medical device and assembly for creating a channel in soft tissue
US20140005705A1 (en) 2012-06-29 2014-01-02 Ethicon Endo-Surgery, Inc. Surgical instruments with articulating shafts
US9351754B2 (en) 2012-06-29 2016-05-31 Ethicon Endo-Surgery, Llc Ultrasonic surgical instruments with distally positioned jaw assemblies
US9226767B2 (en) 2012-06-29 2016-01-05 Ethicon Endo-Surgery, Inc. Closed feedback control for electrosurgical device
US20140005702A1 (en) 2012-06-29 2014-01-02 Ethicon Endo-Surgery, Inc. Ultrasonic surgical instruments with distally positioned transducers
US9820768B2 (en) 2012-06-29 2017-11-21 Ethicon Llc Ultrasonic surgical instruments with control mechanisms
US9393037B2 (en) 2012-06-29 2016-07-19 Ethicon Endo-Surgery, Llc Surgical instruments with articulating shafts
US9198714B2 (en) 2012-06-29 2015-12-01 Ethicon Endo-Surgery, Inc. Haptic feedback devices for surgical robot
US9408622B2 (en) 2012-06-29 2016-08-09 Ethicon Endo-Surgery, Llc Surgical instruments with articulating shafts
US9283045B2 (en) 2012-06-29 2016-03-15 Ethicon Endo-Surgery, Llc Surgical instruments with fluid management system
US9326788B2 (en) 2012-06-29 2016-05-03 Ethicon Endo-Surgery, Llc Lockout mechanism for use with robotic electrosurgical device
US9492224B2 (en) 2012-09-28 2016-11-15 EthiconEndo-Surgery, LLC Multi-function bi-polar forceps
US9498244B2 (en) 2012-10-19 2016-11-22 Iogyn, Inc. Medical systems and methods
US10201365B2 (en) 2012-10-22 2019-02-12 Ethicon Llc Surgeon feedback sensing and display methods
US9095367B2 (en) 2012-10-22 2015-08-04 Ethicon Endo-Surgery, Inc. Flexible harmonic waveguides/blades for surgical instruments
US20140135804A1 (en) 2012-11-15 2014-05-15 Ethicon Endo-Surgery, Inc. Ultrasonic and electrosurgical devices
AU2013348103B2 (en) 2012-11-21 2018-02-22 C.R. Bard, Inc. Core needle biopsy device
US9844408B2 (en) 2012-11-30 2017-12-19 Gyrus Acmi, Inc. Replacable debrider blade module with latching mechanism
WO2014133664A1 (en) * 2013-02-26 2014-09-04 GYRUS ACMI, INC. (d/b/a OLYMPUS SURGICAL TECHNOLOGIES AMERICA) Replaceable debrider blade module with latching mechanism
WO2014164263A1 (en) 2013-03-12 2014-10-09 Bullington Gregory J Methods and apparatus for selectively occluding the lumen of a needle
US9358036B2 (en) 2013-03-12 2016-06-07 Gyrus Acmi, Inc. Blade positioning device
US10226273B2 (en) 2013-03-14 2019-03-12 Ethicon Llc Mechanical fasteners for use with surgical energy devices
US9241728B2 (en) 2013-03-15 2016-01-26 Ethicon Endo-Surgery, Inc. Surgical instrument with multiple clamping mechanisms
EP4306142A2 (en) 2013-04-08 2024-01-17 Boston Scientific Scimed, Inc. Medical systems and methods
US9486233B2 (en) 2013-04-26 2016-11-08 Iogyn, Inc. Tissue resecting systems and methods
CN103271755B (en) * 2013-04-28 2018-08-14 河南科技大学第一附属医院 A kind of Multifunctional kidney puncture needle
US9814514B2 (en) 2013-09-13 2017-11-14 Ethicon Llc Electrosurgical (RF) medical instruments for cutting and coagulating tissue
USD716451S1 (en) 2013-09-24 2014-10-28 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
USD715442S1 (en) 2013-09-24 2014-10-14 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
USD715942S1 (en) 2013-09-24 2014-10-21 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
USD716450S1 (en) 2013-09-24 2014-10-28 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
US9943639B2 (en) 2013-10-28 2018-04-17 Boston Scientific Scimed, Inc. Fluid management system and methods
US9265926B2 (en) 2013-11-08 2016-02-23 Ethicon Endo-Surgery, Llc Electrosurgical devices
US9993231B2 (en) 2013-11-20 2018-06-12 Covidien Lp Devices, systems, and methods for navigating a biopsy tool to a target location and obtaining a tissue sample using the same
GB2521229A (en) 2013-12-16 2015-06-17 Ethicon Endo Surgery Inc Medical device
GB2521228A (en) 2013-12-16 2015-06-17 Ethicon Endo Surgery Inc Medical device
US9795436B2 (en) 2014-01-07 2017-10-24 Ethicon Llc Harvesting energy from a surgical generator
US8815099B1 (en) 2014-01-21 2014-08-26 Laurimed, Llc Devices and methods for filtering and/or collecting tissue
US9554854B2 (en) 2014-03-18 2017-01-31 Ethicon Endo-Surgery, Llc Detecting short circuits in electrosurgical medical devices
US10278680B2 (en) 2014-03-19 2019-05-07 Covidien Lp Devices, systems, and methods for navigating a biopsy tool to a target location and obtaining a tissue sample using the same
US10092310B2 (en) 2014-03-27 2018-10-09 Ethicon Llc Electrosurgical devices
US10463421B2 (en) 2014-03-27 2019-11-05 Ethicon Llc Two stage trigger, clamp and cut bipolar vessel sealer
US9737355B2 (en) 2014-03-31 2017-08-22 Ethicon Llc Controlling impedance rise in electrosurgical medical devices
US9913680B2 (en) 2014-04-15 2018-03-13 Ethicon Llc Software algorithms for electrosurgical instruments
US10667836B2 (en) * 2014-04-28 2020-06-02 Boston Scientific Scimed, Inc. Tissue resectors, hand operated tissue resecting systems, and associated methods
CN106794026A (en) * 2014-05-16 2017-05-31 美国奥林匹斯外科技术吉鲁斯阿克米公司 Device for cutting tissue and method
US10285724B2 (en) 2014-07-31 2019-05-14 Ethicon Llc Actuation mechanisms and load adjustment assemblies for surgical instruments
JP6678674B2 (en) 2014-09-05 2020-04-08 ペイブ,エルエルシー Improvements for a complete core biopsy device
US9387050B2 (en) 2014-09-15 2016-07-12 Gyrus Acmi Inc. Surgical system having detachable component and state detection circuit for detection of state of attachment of detachable component
KR101649177B1 (en) * 2014-11-06 2016-08-19 (주)세원메디텍 Shaver for removing body tissue and Tissue removing device having the shaver
US9693898B2 (en) * 2014-11-19 2017-07-04 Novartis Ag Double-acting vitreous probe with contoured port
US10639092B2 (en) 2014-12-08 2020-05-05 Ethicon Llc Electrode configurations for surgical instruments
US10245095B2 (en) 2015-02-06 2019-04-02 Ethicon Llc Electrosurgical instrument with rotation and articulation mechanisms
US10188456B2 (en) 2015-02-18 2019-01-29 Medtronic Xomed, Inc. Electrode assembly for RF energy enabled tissue debridement device
WO2016134156A1 (en) 2015-02-18 2016-08-25 Medtronic Xomed, Inc. Rf energy enabled tissue debridement device
US10376302B2 (en) 2015-02-18 2019-08-13 Medtronic Xomed, Inc. Rotating electrical connector for RF energy enabled tissue debridement device
US9820825B2 (en) 2015-02-20 2017-11-21 Gyrus Acmi Inc. Surgical system having plurality of detachably attachable components and circuit for detecting target states of detachably attachable components and performing control based on detected target states, and method for providing surgical system
US10342602B2 (en) 2015-03-17 2019-07-09 Ethicon Llc Managing tissue treatment
US10321950B2 (en) 2015-03-17 2019-06-18 Ethicon Llc Managing tissue treatment
US10595929B2 (en) 2015-03-24 2020-03-24 Ethicon Llc Surgical instruments with firing system overload protection mechanisms
WO2016171963A1 (en) 2015-04-21 2016-10-27 Orczy-Timko Benedek Arthroscopic devices and methods
US10646208B2 (en) * 2015-05-06 2020-05-12 Devicor Medical Products, Inc. Marker delivery device for use with MRI breast biopsy system
US10034684B2 (en) 2015-06-15 2018-07-31 Ethicon Llc Apparatus and method for dissecting and coagulating tissue
US11020140B2 (en) 2015-06-17 2021-06-01 Cilag Gmbh International Ultrasonic surgical blade for use with ultrasonic surgical instruments
US11051873B2 (en) 2015-06-30 2021-07-06 Cilag Gmbh International Surgical system with user adaptable techniques employing multiple energy modalities based on tissue parameters
US10898256B2 (en) 2015-06-30 2021-01-26 Ethicon Llc Surgical system with user adaptable techniques based on tissue impedance
US10034704B2 (en) 2015-06-30 2018-07-31 Ethicon Llc Surgical instrument with user adaptable algorithms
US11141213B2 (en) 2015-06-30 2021-10-12 Cilag Gmbh International Surgical instrument with user adaptable techniques
US10357303B2 (en) 2015-06-30 2019-07-23 Ethicon Llc Translatable outer tube for sealing using shielded lap chole dissector
US11129669B2 (en) 2015-06-30 2021-09-28 Cilag Gmbh International Surgical system with user adaptable techniques based on tissue type
US10154852B2 (en) 2015-07-01 2018-12-18 Ethicon Llc Ultrasonic surgical blade with improved cutting and coagulation features
CN108366823B (en) 2015-08-13 2021-04-27 柯惠股份公司 Motorized surgical method and apparatus with variable stiffness capture member
US10751108B2 (en) 2015-09-30 2020-08-25 Ethicon Llc Protection techniques for generator for digitally generating electrosurgical and ultrasonic electrical signal waveforms
US10595930B2 (en) 2015-10-16 2020-03-24 Ethicon Llc Electrode wiping surgical device
US9585675B1 (en) 2015-10-23 2017-03-07 RELIGN Corporation Arthroscopic devices and methods
US9603656B1 (en) 2015-10-23 2017-03-28 RELIGN Corporation Arthroscopic devices and methods
US10179022B2 (en) 2015-12-30 2019-01-15 Ethicon Llc Jaw position impedance limiter for electrosurgical instrument
US10575892B2 (en) 2015-12-31 2020-03-03 Ethicon Llc Adapter for electrical surgical instruments
US11129670B2 (en) 2016-01-15 2021-09-28 Cilag Gmbh International Modular battery powered handheld surgical instrument with selective application of energy based on button displacement, intensity, or local tissue characterization
US10537351B2 (en) 2016-01-15 2020-01-21 Ethicon Llc Modular battery powered handheld surgical instrument with variable motor control limits
US10716615B2 (en) 2016-01-15 2020-07-21 Ethicon Llc Modular battery powered handheld surgical instrument with curved end effectors having asymmetric engagement between jaw and blade
US11229471B2 (en) 2016-01-15 2022-01-25 Cilag Gmbh International Modular battery powered handheld surgical instrument with selective application of energy based on tissue characterization
US10022140B2 (en) 2016-02-04 2018-07-17 RELIGN Corporation Arthroscopic devices and methods
US10555769B2 (en) 2016-02-22 2020-02-11 Ethicon Llc Flexible circuits for electrosurgical instrument
US11207119B2 (en) 2016-03-11 2021-12-28 RELIGN Corporation Arthroscopic devices and methods
US11172953B2 (en) 2016-04-11 2021-11-16 RELIGN Corporation Arthroscopic devices and methods
US10595889B2 (en) 2016-04-11 2020-03-24 RELIGN Corporation Arthroscopic devices and methods
US10646269B2 (en) 2016-04-29 2020-05-12 Ethicon Llc Non-linear jaw gap for electrosurgical instruments
US10702329B2 (en) 2016-04-29 2020-07-07 Ethicon Llc Jaw structure with distal post for electrosurgical instruments
US10485607B2 (en) 2016-04-29 2019-11-26 Ethicon Llc Jaw structure with distal closure for electrosurgical instruments
US10456193B2 (en) 2016-05-03 2019-10-29 Ethicon Llc Medical device with a bilateral jaw configuration for nerve stimulation
US10245064B2 (en) 2016-07-12 2019-04-02 Ethicon Llc Ultrasonic surgical instrument with piezoelectric central lumen transducer
US10893883B2 (en) 2016-07-13 2021-01-19 Ethicon Llc Ultrasonic assembly for use with ultrasonic surgical instruments
US10842522B2 (en) 2016-07-15 2020-11-24 Ethicon Llc Ultrasonic surgical instruments having offset blades
US10376305B2 (en) 2016-08-05 2019-08-13 Ethicon Llc Methods and systems for advanced harmonic energy
US10285723B2 (en) 2016-08-09 2019-05-14 Ethicon Llc Ultrasonic surgical blade with improved heel portion
USD847990S1 (en) 2016-08-16 2019-05-07 Ethicon Llc Surgical instrument
US10828056B2 (en) 2016-08-25 2020-11-10 Ethicon Llc Ultrasonic transducer to waveguide acoustic coupling, connections, and configurations
US10952759B2 (en) 2016-08-25 2021-03-23 Ethicon Llc Tissue loading of a surgical instrument
EP4215124A1 (en) 2016-11-21 2023-07-26 C. R. Bard, Inc. Biopsy device having a hydraulic drive assembly
US10945713B2 (en) 2016-11-23 2021-03-16 C. R. Bard, Inc. Single insertion multiple sample biopsy apparatus
US10603064B2 (en) 2016-11-28 2020-03-31 Ethicon Llc Ultrasonic transducer
US11266430B2 (en) 2016-11-29 2022-03-08 Cilag Gmbh International End effector control and calibration
US10709429B2 (en) 2016-12-05 2020-07-14 Argon Medical Devices Inc. Biopsy device handle
EP3338646A1 (en) 2016-12-21 2018-06-27 National University of Ireland Galway A biopsy device
US11426231B2 (en) 2017-01-11 2022-08-30 RELIGN Corporation Arthroscopic devices and methods
US10820893B2 (en) 2017-02-15 2020-11-03 Cook Medical Technologies Llc Endoscopic tri-point biopsy needle
US11065023B2 (en) 2017-03-17 2021-07-20 RELIGN Corporation Arthroscopic devices and methods
IL251684B (en) 2017-04-09 2019-01-31 Tel Hashomer Medical Res Infrastructure & Services Ltd Device and method for creating a channel in soft tissue
US10820920B2 (en) 2017-07-05 2020-11-03 Ethicon Llc Reusable ultrasonic medical devices and methods of their use
CN108186059B (en) * 2018-03-13 2020-07-28 湖州市妇幼保健院 Gastrointestinal endoscope biopsy picking device
KR200487712Y1 (en) * 2018-06-19 2018-10-24 김주원 Shaver For Surgery
US10576248B2 (en) * 2018-07-23 2020-03-03 Crossbay Medical, Inc. Apparatus and method for everting catheter for uterine access for biopsy and cytology
CN109820542A (en) * 2019-02-01 2019-05-31 何定甫 Breast biopsy sample probe
CN110074826A (en) * 2019-05-20 2019-08-02 温州医科大学附属第一医院 Biopsy catheter
SE1950644A1 (en) * 2019-05-29 2020-10-20 Szafran Biopsy Ab A biopsy tool for removing a tissue sample
EP3989795A1 (en) 2019-06-27 2022-05-04 Boston Scientific Scimed, Inc. Detection of an endoscope to a fluid management system
US11413057B2 (en) * 2019-06-27 2022-08-16 Covidien Lp Tissue resecting instruments including auxiliary vacuum features
CN110522479A (en) * 2019-08-07 2019-12-03 沈毅 A kind of second mining formula Pleura biopsy needle
US20210196359A1 (en) 2019-12-30 2021-07-01 Ethicon Llc Electrosurgical instruments with electrodes having energy focusing features
US11812957B2 (en) 2019-12-30 2023-11-14 Cilag Gmbh International Surgical instrument comprising a signal interference resolution system
US11696776B2 (en) 2019-12-30 2023-07-11 Cilag Gmbh International Articulatable surgical instrument
US11723716B2 (en) 2019-12-30 2023-08-15 Cilag Gmbh International Electrosurgical instrument with variable control mechanisms
US11786291B2 (en) 2019-12-30 2023-10-17 Cilag Gmbh International Deflectable support of RF energy electrode with respect to opposing ultrasonic blade
US11684412B2 (en) 2019-12-30 2023-06-27 Cilag Gmbh International Surgical instrument with rotatable and articulatable surgical end effector
US11779329B2 (en) 2019-12-30 2023-10-10 Cilag Gmbh International Surgical instrument comprising a flex circuit including a sensor system
US11660089B2 (en) 2019-12-30 2023-05-30 Cilag Gmbh International Surgical instrument comprising a sensing system
US11911063B2 (en) 2019-12-30 2024-02-27 Cilag Gmbh International Techniques for detecting ultrasonic blade to electrode contact and reducing power to ultrasonic blade
US11452525B2 (en) 2019-12-30 2022-09-27 Cilag Gmbh International Surgical instrument comprising an adjustment system
US11759251B2 (en) 2019-12-30 2023-09-19 Cilag Gmbh International Control program adaptation based on device status and user input
US11779387B2 (en) 2019-12-30 2023-10-10 Cilag Gmbh International Clamp arm jaw to minimize tissue sticking and improve tissue control
EP4093295B1 (en) * 2020-03-04 2024-01-24 Devicor Medical Products, Inc. Slide-lock for biopsy device
US20210282837A1 (en) * 2020-03-11 2021-09-16 Covidien Lp Thermal cutting-assisted tissue resection devices and systems
US11129601B1 (en) 2020-04-29 2021-09-28 Thomas Paul Huber Endoscopic suction biopsy catheter with no moving parts
CN111700652B (en) * 2020-06-28 2023-10-31 西安交通大学医学院第一附属医院 Sampler for skin venereal disease
WO2023163702A1 (en) * 2022-02-24 2023-08-31 Intersect ENT International GmbH Illumination assembly for handheld medical devices and instruments

Citations (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3326785A (en) * 1962-09-17 1967-06-20 Anocut Eng Co Electrolytic polishing apparatus and method
US3805791A (en) * 1971-07-01 1974-04-23 K Seuberth Apparatus for the diathermic removal of growths
US3844272A (en) * 1969-02-14 1974-10-29 A Banko Surgical instruments
US3910279A (en) * 1973-06-20 1975-10-07 Olympus Optical Co Electrosurgical instrument
US3945375A (en) * 1972-04-04 1976-03-23 Surgical Design Corporation Rotatable surgical instrument
US4007732A (en) * 1975-09-02 1977-02-15 Robert Carl Kvavle Method for location and removal of soft tissue in human biopsy operations
US4243048A (en) * 1976-09-21 1981-01-06 Jim Zegeer Biopsy device
US4294254A (en) * 1977-12-08 1981-10-13 Chamness Dale L Surgical apparatus
US4311143A (en) * 1978-10-12 1982-01-19 Olympus Optical Co., Ltd. Apparatus for resecting tissue inside the body cavity utilizing high-frequency currents
US4362160A (en) * 1979-07-24 1982-12-07 Richard Wolf Gmbh Endoscopes
US4503855A (en) * 1981-12-31 1985-03-12 Harald Maslanka High frequency surgical snare electrode
US4576162A (en) * 1983-03-30 1986-03-18 Mccorkle Charles E Apparatus and method for separation of scar tissue in venous pathway
US4682606A (en) * 1986-02-03 1987-07-28 Decaprio Vincent H Localizing biopsy apparatus
US4926858A (en) * 1984-05-30 1990-05-22 Devices For Vascular Intervention, Inc. Atherectomy device for severe occlusions
US5047027A (en) * 1990-04-20 1991-09-10 Everest Medical Corporation Tumor resector
US5059204A (en) * 1989-10-26 1991-10-22 Site Microsurgical Systems, Inc. Ocular cutter with enhanced cutting action
US5064424A (en) * 1989-05-18 1991-11-12 Richard Wolf Gmbh Electro-surgical instrument
US5080660A (en) * 1990-05-11 1992-01-14 Applied Urology, Inc. Electrosurgical electrode
US5085659A (en) * 1990-11-21 1992-02-04 Everest Medical Corporation Biopsy device with bipolar coagulation capability
US5133360A (en) * 1991-03-07 1992-07-28 Spears Colin P Spears retriever
US5133359A (en) * 1990-11-14 1992-07-28 Du-Kedem Technologies Ltd. Hard tissue biopsy instrument with rotary drive
USRE34056E (en) * 1989-07-31 1992-09-08 C.R. Bard, Inc. Tissue sampling device
US5158561A (en) * 1992-03-23 1992-10-27 Everest Medical Corporation Monopolar polypectomy snare with coagulation electrode
US5217458A (en) * 1992-04-09 1993-06-08 Everest Medical Corporation Bipolar biopsy device utilizing a rotatable, single-hinged moving element
US5320613A (en) * 1993-01-06 1994-06-14 Scimed Life Systems, Inc. Medical lumen flushing and guide wire loading device and method
US5335671A (en) * 1989-11-06 1994-08-09 Mectra Labs, Inc. Tissue removal assembly with provision for an electro-cautery device
US5441503A (en) * 1988-09-24 1995-08-15 Considine; John Apparatus for removing tumors from hollow organs of the body
US5470308A (en) * 1992-08-12 1995-11-28 Vidamed, Inc. Medical probe with biopsy stylet
US5477862A (en) * 1994-03-14 1995-12-26 Haaga; John R. Cutting tip for biopsy needle
US5488958A (en) * 1992-11-09 1996-02-06 Vance Products Incorporated Surgical cutting instrument for coring tissue affixed thereto
US5507743A (en) * 1993-11-08 1996-04-16 Zomed International Coiled RF electrode treatment apparatus
US5527331A (en) * 1993-10-13 1996-06-18 Femrx Method for prostatic tissue resection
US5526822A (en) * 1994-03-24 1996-06-18 Biopsys Medical, Inc. Method and apparatus for automated biopsy and collection of soft tissue
US5538010A (en) * 1994-10-05 1996-07-23 Proact Ltd. Biopsy needle device
US5578030A (en) * 1994-11-04 1996-11-26 Levin; John M. Biopsy needle with cauterization feature
US5595185A (en) * 1994-08-11 1997-01-21 N.M.B. Medical Applications Ltd. Single puncture multi-biopsy gun
US5649547A (en) * 1994-03-24 1997-07-22 Biopsys Medical, Inc. Methods and devices for automated biopsy and collection of soft tissue
US5687739A (en) * 1995-12-06 1997-11-18 Interventional Concepts, Inc. Biopsy specimen cutter
US5769086A (en) * 1995-12-06 1998-06-23 Biopsys Medical, Inc. Control system and method for automated biopsy device
US5782775A (en) * 1995-10-20 1998-07-21 United States Surgical Corporation Apparatus and method for localizing and removing tissue
US5797907A (en) * 1989-11-06 1998-08-25 Mectra Labs, Inc. Electrocautery cutter
US5810806A (en) * 1996-08-29 1998-09-22 Ethicon Endo-Surgery Methods and devices for collection of soft tissue
US5814044A (en) * 1995-02-10 1998-09-29 Enable Medical Corporation Apparatus and method for morselating and removing tissue from a patient
US5846513A (en) * 1997-07-08 1998-12-08 Carewise Medical Products Corporation Tumor localization and removal system using penetratable detection probe and removal instrument
US5848978A (en) * 1995-11-14 1998-12-15 Genx International, Inc. Surgical biopsy device
US5857981A (en) * 1995-09-12 1999-01-12 Bucalo; Brian D. Biopsy instrument with tissue specimen retaining and retrieval device
US5857982A (en) * 1995-09-08 1999-01-12 United States Surgical Corporation Apparatus and method for removing tissue
US5876340A (en) * 1997-04-17 1999-03-02 Irvine Biomedical, Inc. Ablation apparatus with ultrasonic imaging capabilities
US5882316A (en) * 1996-08-29 1999-03-16 City Of Hope Minimally invasive biopsy device
US5902272A (en) * 1992-01-07 1999-05-11 Arthrocare Corporation Planar ablation probe and method for electrosurgical cutting and ablation
US5913857A (en) * 1996-08-29 1999-06-22 Ethicon End0-Surgery, Inc. Methods and devices for collection of soft tissue
US5925044A (en) * 1996-07-01 1999-07-20 Gebrueder Berchtold Gmbh & Co. Trocar for laparoscopic operations
US5947964A (en) * 1995-03-03 1999-09-07 Neothermia Corporation Methods and apparatus for therapeutic cauterization of predetermined volumes of biological tissue
US5954670A (en) * 1994-10-05 1999-09-21 Baker; Gary H. Mandrel-guided tandem multiple channel biopsy guide device and method of use
US5964716A (en) * 1998-05-14 1999-10-12 Ethicon Endo-Surgery, Inc. Method of use for a multi-port biopsy instrument
US5984919A (en) * 1991-02-13 1999-11-16 Applied Medical Resources Corporation Surgical trocar
US5997560A (en) * 1994-07-21 1999-12-07 Sdgi Holdings, Inc. Surgical cutting instrument
US6050955A (en) * 1997-09-19 2000-04-18 United States Surgical Corporation Biopsy apparatus and method
US6056700A (en) * 1998-10-13 2000-05-02 Emx, Inc. Biopsy marker assembly and method of use
US6086543A (en) * 1998-06-24 2000-07-11 Rubicor Medical, Inc. Fine needle and core biopsy devices and methods
US6120462A (en) * 1999-03-31 2000-09-19 Ethicon Endo-Surgery, Inc. Control method for an automated surgical biopsy device
US6142955A (en) * 1997-09-19 2000-11-07 United States Surgical Corporation Biopsy apparatus and method
US6258000B1 (en) * 1998-05-21 2001-07-10 Liechty, Ii Victor Jay Penetration enhancing aerodynamically favorable arrowhead
US6261241B1 (en) * 1998-03-03 2001-07-17 Senorx, Inc. Electrosurgical biopsy device and method
US6277083B1 (en) * 1999-12-27 2001-08-21 Neothermia Corporation Minimally invasive intact recovery of tissue
US6312429B1 (en) * 1998-09-01 2001-11-06 Senorx, Inc. Electrosurgical lesion location device
US20030004407A1 (en) * 1997-11-18 2003-01-02 Carewise Medical Products Corporation Minimally invasive surgical
US6514248B1 (en) * 1999-10-15 2003-02-04 Neothermia Corporation Accurate cutting about and into tissue volumes with electrosurgically deployed electrodes
US6514215B1 (en) * 1999-10-13 2003-02-04 Pentax Corporation Endoscopic tissue collecting instrument
US6540695B1 (en) * 1998-04-08 2003-04-01 Senorx, Inc. Biopsy anchor device with cutter
US20030125639A1 (en) * 2002-01-02 2003-07-03 Fisher John S. Biopsy needle having rotating core for shearing tissue
US6689145B2 (en) * 1998-09-03 2004-02-10 Rubicor Medical, Inc. Excisional biopsy devices and methods
US6758824B1 (en) * 2000-11-06 2004-07-06 Suros Surgical Systems, Inc. Biopsy apparatus
US6835173B2 (en) * 2001-10-05 2004-12-28 Scimed Life Systems, Inc. Robotic endoscope
US7189206B2 (en) * 2003-02-24 2007-03-13 Senorx, Inc. Biopsy device with inner cutter

Family Cites Families (139)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US34056A (en) * 1862-01-07 Edwin gomez
US2032860A (en) 1933-03-24 1936-03-03 Wappler Frederick Charles Method for electrosurgical treatment of tissue
DE1225813B (en) 1961-10-23 1966-09-29 Optique Et Prec De Levallois S Suction biopsy probe
DE1761358B2 (en) 1967-05-12 1973-08-23 Adamovske strojirny, N P, Adamov (Tschechoslowakei) SIDE PULLER FOR THE LATERAL ALIGNMENT OF PAPER SHEETS ON PRINTING MACHINES
US3847153A (en) 1973-09-14 1974-11-12 B Weissman Disposable probe tip for electro-surgical device
US3902498A (en) * 1974-03-04 1975-09-02 Minnesota Mining & Mfg Surgical cutting instrument
US3955578A (en) 1974-12-23 1976-05-11 Cook Inc. Rotatable surgical snare
AT361106B (en) 1976-03-19 1981-02-25 Hamer Geerd SURGICAL CUTTER
CH602084A5 (en) 1976-06-08 1978-07-31 Kaspar Menzi Medical spatula for throat examination
GB2011258A (en) 1977-11-18 1979-07-11 Wolf Gmbh Richard Device for removing excrescences and polyps
US4565200A (en) 1980-09-24 1986-01-21 Cosman Eric R Universal lesion and recording electrode system
US4461305A (en) 1981-09-04 1984-07-24 Cibley Leonard J Automated biopsy device
DE3202193A1 (en) * 1982-01-25 1983-08-04 Merck Patent Gmbh, 6100 Darmstadt SURGICAL BONE GRINDING INSTRUMENT
US4394254A (en) * 1982-04-26 1983-07-19 Texaco Inc. Method for separating straight chain hydrocarbons using zeolites having large crystals
US5507764A (en) * 1982-09-24 1996-04-16 Joseph J. Berke Powered rotary scalpel method
US4603694A (en) 1983-03-08 1986-08-05 Richards Medical Company Arthroscopic shaver
US4660267A (en) 1983-03-08 1987-04-28 Richards Medical Company Method for fabricating an arthroscopic shaver
DE3419962A1 (en) 1983-05-30 1984-12-06 Olympus Optical Co., Ltd., Tokio/Tokyo HIGH FREQUENCY INCISION AND EXCISION INSTRUMENT
CH661199A5 (en) 1983-12-22 1987-07-15 Sulzer Ag MARKING IMPLANT.
USRE33925E (en) 1984-05-22 1992-05-12 Cordis Corporation Electrosurgical catheter aned method for vascular applications
JPS6176147A (en) 1984-09-21 1986-04-18 オリンパス光学工業株式会社 High frequency incision appliance
US4724836A (en) 1985-01-08 1988-02-16 Olympus Optical Co., Ltd. High-frequency incision tool
US4718419A (en) 1985-08-05 1988-01-12 Olympus Optical Co., Ltd. Snare assembly for endoscope
US4800896A (en) 1985-11-08 1989-01-31 Jalowayski Alfredo A Cell sample collector probe
DE3789320T2 (en) 1986-07-30 1994-06-09 Sumitomo Pharma Administration instrument for the introduction of solid medication.
US4983179A (en) 1986-12-30 1991-01-08 Smith & Nephew Dyonics Inc. Arthroscopic surgical instrument
US5041124A (en) 1989-07-14 1991-08-20 Kensey Nash Corporation Apparatus and method for sclerosing of body tissue
US5007908A (en) 1989-09-29 1991-04-16 Everest Medical Corporation Electrosurgical instrument having needle cutting electrode and spot-coag electrode
JPH06114070A (en) 1990-06-22 1994-04-26 Vance Prod Inc Tissue abscission device for surgery
US5275609A (en) * 1990-06-22 1994-01-04 Vance Products Incorporated Surgical cutting instrument
US5100423A (en) 1990-08-21 1992-03-31 Medical Engineering & Development Institute, Inc. Ablation catheter
US5282799A (en) 1990-08-24 1994-02-01 Everest Medical Corporation Bipolar electrosurgical scalpel with paired loop electrodes
US5219350A (en) 1990-10-05 1993-06-15 Emerson Clarence A Medical instrument
US5242460A (en) 1990-10-25 1993-09-07 Devices For Vascular Intervention, Inc. Atherectomy catheter having axially-disposed cutting edge
JPH05506176A (en) 1991-02-13 1993-09-16 アプライド メディカル リソーセス インコーポレイテッド surgical trocar
US5599347A (en) 1991-02-13 1997-02-04 Applied Medical Resources Corporation Surgical trocar with cutoff circuit
US5324288A (en) 1991-04-30 1994-06-28 Utah Medical Products, Inc. Electrosurgical loop with a depth gauge
US5285795A (en) 1991-09-12 1994-02-15 Surgical Dynamics, Inc. Percutaneous discectomy system having a bendable discectomy probe and a steerable cannula
US5395312A (en) 1991-10-18 1995-03-07 Desai; Ashvin Surgical tool
KR0145453B1 (en) 1992-01-21 1998-07-01 알렌 제이 Electrosurgical trocar control device
US5602449A (en) 1992-04-13 1997-02-11 Smith & Nephew Endoscopy, Inc. Motor controlled surgical system and method having positional control
US5653718A (en) 1994-05-16 1997-08-05 Yoon; Inbae Cannula anchoring system
US5311859A (en) 1992-09-11 1994-05-17 Welch Allyn, Inc. Add-on video camera arrangement for optical laparoscope
US5380321A (en) 1992-11-04 1995-01-10 Yoon; Inbae Shielded energy transmitting surgical instrument and methods therefor
US5575794A (en) 1993-02-12 1996-11-19 Walus; Richard L. Tool for implanting a fiducial marker
US5423330A (en) 1993-03-10 1995-06-13 The University Of Miami Capsule suction punch instrument and method of use
US5897567A (en) * 1993-04-29 1999-04-27 Scimed Life Systems, Inc. Expandable intravascular occlusion material removal devices and methods of use
US5417687A (en) 1993-04-30 1995-05-23 Medical Scientific, Inc. Bipolar electrosurgical trocar
GB9314640D0 (en) 1993-07-15 1993-08-25 Salim Aws S M Tunnellimg catheter
US5501654A (en) 1993-07-15 1996-03-26 Ethicon, Inc. Endoscopic instrument having articulating element
GB9314641D0 (en) 1993-07-15 1993-08-25 Salim Aws S M Tunnelling umbrella
US5374188A (en) 1993-07-19 1994-12-20 Bei Medical Systems, Inc. Electro-surgical instrument and method for use with dental implantations
AU7404994A (en) 1993-07-30 1995-02-28 Regents Of The University Of California, The Endocardial infusion catheter
US5415656A (en) 1993-09-28 1995-05-16 American Medical Systems, Inc. Electrosurgical apparatus
US5437665A (en) 1993-10-12 1995-08-01 Munro; Malcolm G. Electrosurgical loop electrode instrument for laparoscopic surgery
US5728143A (en) 1995-08-15 1998-03-17 Rita Medical Systems, Inc. Multiple antenna ablation apparatus and method
US5683384A (en) 1993-11-08 1997-11-04 Zomed Multiple antenna ablation apparatus
US5366468A (en) * 1993-11-09 1994-11-22 Linvatec Corporation Double bladed surgical router having aspiration ports within flutes
US5441498A (en) 1994-02-16 1995-08-15 Envision Surgical Systems, Inc. Method of using a multimodality probe with extendable bipolar electrodes
US5445142A (en) 1994-03-15 1995-08-29 Ethicon Endo-Surgery, Inc. Surgical trocars having optical tips defining one or more viewing ports
US5476102A (en) 1994-06-29 1995-12-19 Baxter International Inc. Biopsy needle assembly and guide
US5794626A (en) 1994-08-18 1998-08-18 Kieturakis; Maciej J. Excisional stereotactic apparatus
DE69534233T2 (en) 1994-09-16 2005-10-27 Ethicon Endo-Surgery, Inc., Cincinnati DEVICES FOR DETERMINING AND MARKING TISSUE
US5601583A (en) * 1995-02-15 1997-02-11 Smith & Nephew Endoscopy Inc. Surgical instrument
US5856340A (en) * 1995-02-28 1999-01-05 Eli Lilly And Company Method of treating estrogen dependent cancers
CA2168694A1 (en) 1995-03-20 1996-09-21 Wayne P. Young Trocar assembly with electrocautery penetrating tip
US5873886A (en) 1995-04-04 1999-02-23 United States Surgical Corporation Surgical cutting apparatus
DE19528440C2 (en) 1995-08-02 1998-09-10 Harald Dr Med Kuebler Surgical cutting instrument
CA2187975C (en) 1995-10-20 2001-05-01 Lisa W. Heaton Surgical apparatus and method for marking tissue location
US5782764A (en) 1995-11-07 1998-07-21 Iti Medical Technologies, Inc. Fiber composite invasive medical instruments and methods for use in interventional imaging procedures
US5676663A (en) 1995-11-21 1997-10-14 Kim; David S. Cone biopsy instrument
CA2197368A1 (en) * 1996-02-15 1997-08-16 Daniel J. Smith Radiused hollow cutting edge needle
US5792142A (en) * 1996-02-16 1998-08-11 Howmedica, Inc. Cutting tip
US5823970A (en) * 1996-03-22 1998-10-20 Medical Device Technologies, Inc. Biopsy needle set
DE19706751A1 (en) 1996-03-27 1997-10-02 Valleylab Inc Electrosurgical device for removing tissue in body areas
US5908433A (en) 1996-05-10 1999-06-01 Stryker Corporation Carpal tunnel knife
US6258111B1 (en) 1997-10-03 2001-07-10 Scieran Technologies, Inc. Apparatus and method for performing ophthalmic procedures
US5910150A (en) 1996-12-02 1999-06-08 Angiotrax, Inc. Apparatus for performing surgery
US5759154A (en) * 1996-12-23 1998-06-02 C. R. Bard, Inc. Print mask technique for echogenic enhancement of a medical device
CA2201458C (en) 1997-04-01 2001-06-12 George A. Vilos Improved resectoscope
US6024751A (en) 1997-04-11 2000-02-15 Coherent Inc. Method and apparatus for transurethral resection of the prostate
US6156049A (en) 1997-04-11 2000-12-05 Coherent Inc. Method and apparatus for transurethral resection of the prostate
US5871454A (en) * 1997-04-22 1999-02-16 Majlessi; Heshmat Percutaneous excisional biopsy device
US6494881B1 (en) 1997-09-30 2002-12-17 Scimed Life Systems, Inc. Apparatus and method for electrode-surgical tissue removal having a selectively insulated electrode
AU9326498A (en) 1997-11-24 1999-06-10 Johnson & Johnson Research Pty. Limited Biopsy instrument with continuous tissue receiving chamber
US6344026B1 (en) 1998-04-08 2002-02-05 Senorx, Inc. Tissue specimen encapsulation device and method thereof
US6540693B2 (en) 1998-03-03 2003-04-01 Senorx, Inc. Methods and apparatus for securing medical instruments to desired locations in a patients body
US6331166B1 (en) 1998-03-03 2001-12-18 Senorx, Inc. Breast biopsy system and method
US6471700B1 (en) 1998-04-08 2002-10-29 Senorx, Inc. Apparatus and method for accessing biopsy site
US6638234B2 (en) 1998-03-03 2003-10-28 Senorx, Inc. Sentinel node location and biopsy
US6454727B1 (en) 1998-03-03 2002-09-24 Senorx, Inc. Tissue acquisition system and method of use
US6139562A (en) * 1998-03-30 2000-10-31 Agilent Technologies, Inc. Apparatus and method for incising
US6610026B2 (en) 1998-05-01 2003-08-26 Sub-Q, Inc. Method of hydrating a sponge material for delivery to a body
US6077230A (en) * 1998-05-14 2000-06-20 Ethicon Endo-Surgery, Inc. Biopsy instrument with removable extractor
US6261302B1 (en) 1998-06-26 2001-07-17 Ethicon Endo-Surgery, Inc. Applier for implantable surgical marker
US6007497A (en) 1998-06-30 1999-12-28 Ethicon Endo-Surgery, Inc. Surgical biopsy device
US6220248B1 (en) 1998-10-21 2001-04-24 Ethicon Endo-Surgery, Inc. Method for implanting a biopsy marker
US8282573B2 (en) 2003-02-24 2012-10-09 Senorx, Inc. Biopsy device with selectable tissue receiving aperture orientation and site illumination
US6689146B1 (en) * 1999-04-29 2004-02-10 Stryker Corporation Powered surgical handpiece with integrated irrigator and suction application
EP1408839A1 (en) 1999-06-17 2004-04-21 Kai Dr. Desinger Surgical, grooved director for collecting tissue in a minimally invasive manner
US6575991B1 (en) 1999-06-17 2003-06-10 Inrad, Inc. Apparatus for the percutaneous marking of a lesion
US6221003B1 (en) 1999-07-26 2001-04-24 Indigo Medical, Incorporated Brachytherapy cartridge including absorbable and autoclaveable spacer
AU8026600A (en) 1999-10-15 2001-04-30 Deschutes Medical Products, Inc. Brachytherapy instrument and methods
US6471659B2 (en) * 1999-12-27 2002-10-29 Neothermia Corporation Minimally invasive intact recovery of tissue
US6428487B1 (en) 1999-12-17 2002-08-06 Ethicon Endo-Surgery, Inc. Surgical biopsy system with remote control for selecting an operational mode
DE10066004A1 (en) 1999-12-29 2001-12-20 Kaltenbach & Voigt Medical or dental medical treatment instrument with electrical load, e.g. light source, has inductive current transfer coils connected to supply lead mounted on front and rear instrument parts
US6200237B1 (en) * 2000-01-09 2001-03-13 Barrie Archery, Llc Sliding body expanding broadhead
US6599237B1 (en) 2000-01-10 2003-07-29 Errol O. Singh Instrument and method for facilitating endoscopic examination and surgical procedures
FR2804608B1 (en) 2000-02-09 2003-02-14 Vygon DEVICE FOR FACILITATING THREADING OF A CATHETER TUBE ON A GUIDE AND ASSEMBLY FOR IMPLEMENTING THE SELDINGER TECHNIQUE
US6231522B1 (en) 2000-02-18 2001-05-15 Ethicon Endo-Surgery, Inc. Biopsy instrument with breakable sample segments
US6350244B1 (en) 2000-02-21 2002-02-26 Biopsy Sciences, Llc Bioabsorable markers for use in biopsy procedures
WO2001087405A2 (en) 2000-05-18 2001-11-22 Integrated Implant Systems, L.L.C. Drive mechanism for medical seed implanting instrument
JP2002034913A (en) 2000-07-27 2002-02-05 Asahi Optical Co Ltd Optical system of light source device in electronic endoscope system
US6773443B2 (en) 2000-07-31 2004-08-10 Regents Of The University Of Minnesota Method and apparatus for taking a biopsy
US6485436B1 (en) * 2000-08-10 2002-11-26 Csaba Truckai Pressure-assisted biopsy needle apparatus and technique
US6712773B1 (en) * 2000-09-11 2004-03-30 Tyco Healthcare Group Lp Biopsy system
CA2321443A1 (en) 2000-09-29 2002-03-29 Mammoco Inc. Device for permanently marking a selected tissue location within a patient's body
JP4064243B2 (en) 2000-11-06 2008-03-19 スルーズ サージカル システムズ、インク Biological tissue examination device
WO2002062227A1 (en) 2001-02-05 2002-08-15 Tyco Healthcare Group Lp Biopsy apparatus and method
WO2002062229A2 (en) * 2001-02-05 2002-08-15 Tyco Healthcare Group Lp Biopsy apparatus and method
US20020105797A1 (en) * 2001-02-06 2002-08-08 Technology Creations, Inc. Tool light and method of use
US6673023B2 (en) * 2001-03-23 2004-01-06 Stryker Puerto Rico Limited Micro-invasive breast biopsy device
US6562032B1 (en) 2001-03-26 2003-05-13 Ellman Alan G Electrosurgical instrument with vibration
US6530891B2 (en) 2001-04-02 2003-03-11 Temple University Of The Commonwealth System Of Higher Education Multiple biopsy device
US6709408B2 (en) * 2001-08-09 2004-03-23 Biopsy Sciences, Llc Dual action aspiration biopsy needle
US7510563B2 (en) 2001-10-26 2009-03-31 Smith & Nephew, Inc. Reciprocating rotary arthroscopic surgical instrument
CA2479349C (en) * 2002-03-19 2012-07-03 Bard Dublin Itc Limited Biopsy device and biopsy needle module that can be inserted into the biopsy device
US6957097B2 (en) * 2002-04-17 2005-10-18 The Board Of Trustees Of The Leland Stanford Junior University Rapid measurement of time-averaged blood flow using ungated spiral phase-contrast MRI
US7740597B2 (en) 2002-12-11 2010-06-22 Ethicon Endo-Surgery, Inc. Biopsy device with sample tube
US20050119562A1 (en) 2003-05-23 2005-06-02 Senorx, Inc. Fibrous marker formed of synthetic polymer strands
US20070005005A1 (en) 2003-08-29 2007-01-04 Wang Fang N Method and apparatus for dosing solids
US9408592B2 (en) 2003-12-23 2016-08-09 Senorx, Inc. Biopsy device with aperture orientation and improved tip
US7452357B2 (en) 2004-10-22 2008-11-18 Ethicon Endo-Surgery, Inc. System and method for planning treatment of tissue
US7517322B2 (en) * 2005-03-04 2009-04-14 Ethicon Endo-Surgery, Inc. Biopsy device with variable side aperture
US20060217635A1 (en) * 2005-03-24 2006-09-28 Mccombs Elizabeth S Biopsy device marker deployment
CN102225024B (en) * 2005-07-21 2013-05-01 泰科医疗集团有限合伙公司 Systems and methods for treating a hollow anatomical structure
US8162852B2 (en) * 2008-10-23 2012-04-24 Devicor Medical Products, Inc. Methods for medical device alignment
US20100106015A1 (en) * 2008-10-23 2010-04-29 Norris Perry R Medical device alignment
CA2751273A1 (en) * 2009-03-16 2010-09-23 C.R. Bard, Inc. Biopsy device having rotational cutting

Patent Citations (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3326785A (en) * 1962-09-17 1967-06-20 Anocut Eng Co Electrolytic polishing apparatus and method
US3844272A (en) * 1969-02-14 1974-10-29 A Banko Surgical instruments
US3805791A (en) * 1971-07-01 1974-04-23 K Seuberth Apparatus for the diathermic removal of growths
US3945375A (en) * 1972-04-04 1976-03-23 Surgical Design Corporation Rotatable surgical instrument
US3910279A (en) * 1973-06-20 1975-10-07 Olympus Optical Co Electrosurgical instrument
US4007732A (en) * 1975-09-02 1977-02-15 Robert Carl Kvavle Method for location and removal of soft tissue in human biopsy operations
US4243048A (en) * 1976-09-21 1981-01-06 Jim Zegeer Biopsy device
US4294254A (en) * 1977-12-08 1981-10-13 Chamness Dale L Surgical apparatus
US4311143A (en) * 1978-10-12 1982-01-19 Olympus Optical Co., Ltd. Apparatus for resecting tissue inside the body cavity utilizing high-frequency currents
US4362160A (en) * 1979-07-24 1982-12-07 Richard Wolf Gmbh Endoscopes
US4503855A (en) * 1981-12-31 1985-03-12 Harald Maslanka High frequency surgical snare electrode
US4576162A (en) * 1983-03-30 1986-03-18 Mccorkle Charles E Apparatus and method for separation of scar tissue in venous pathway
US4926858A (en) * 1984-05-30 1990-05-22 Devices For Vascular Intervention, Inc. Atherectomy device for severe occlusions
US4682606A (en) * 1986-02-03 1987-07-28 Decaprio Vincent H Localizing biopsy apparatus
US5441503A (en) * 1988-09-24 1995-08-15 Considine; John Apparatus for removing tumors from hollow organs of the body
US5064424A (en) * 1989-05-18 1991-11-12 Richard Wolf Gmbh Electro-surgical instrument
USRE34056E (en) * 1989-07-31 1992-09-08 C.R. Bard, Inc. Tissue sampling device
US5059204A (en) * 1989-10-26 1991-10-22 Site Microsurgical Systems, Inc. Ocular cutter with enhanced cutting action
US5335671A (en) * 1989-11-06 1994-08-09 Mectra Labs, Inc. Tissue removal assembly with provision for an electro-cautery device
US5797907A (en) * 1989-11-06 1998-08-25 Mectra Labs, Inc. Electrocautery cutter
US5047027A (en) * 1990-04-20 1991-09-10 Everest Medical Corporation Tumor resector
US5080660A (en) * 1990-05-11 1992-01-14 Applied Urology, Inc. Electrosurgical electrode
US5133359A (en) * 1990-11-14 1992-07-28 Du-Kedem Technologies Ltd. Hard tissue biopsy instrument with rotary drive
US5085659A (en) * 1990-11-21 1992-02-04 Everest Medical Corporation Biopsy device with bipolar coagulation capability
US5984919A (en) * 1991-02-13 1999-11-16 Applied Medical Resources Corporation Surgical trocar
US5133360A (en) * 1991-03-07 1992-07-28 Spears Colin P Spears retriever
US5902272A (en) * 1992-01-07 1999-05-11 Arthrocare Corporation Planar ablation probe and method for electrosurgical cutting and ablation
US5158561A (en) * 1992-03-23 1992-10-27 Everest Medical Corporation Monopolar polypectomy snare with coagulation electrode
US5217458A (en) * 1992-04-09 1993-06-08 Everest Medical Corporation Bipolar biopsy device utilizing a rotatable, single-hinged moving element
US5470308A (en) * 1992-08-12 1995-11-28 Vidamed, Inc. Medical probe with biopsy stylet
US5607389A (en) * 1992-08-12 1997-03-04 Vidamed, Inc. Medical probe with biopsy stylet
US5488958A (en) * 1992-11-09 1996-02-06 Vance Products Incorporated Surgical cutting instrument for coring tissue affixed thereto
US5320613A (en) * 1993-01-06 1994-06-14 Scimed Life Systems, Inc. Medical lumen flushing and guide wire loading device and method
US5527331A (en) * 1993-10-13 1996-06-18 Femrx Method for prostatic tissue resection
US5507743A (en) * 1993-11-08 1996-04-16 Zomed International Coiled RF electrode treatment apparatus
US5477862A (en) * 1994-03-14 1995-12-26 Haaga; John R. Cutting tip for biopsy needle
US5526822A (en) * 1994-03-24 1996-06-18 Biopsys Medical, Inc. Method and apparatus for automated biopsy and collection of soft tissue
US20040019299A1 (en) * 1994-03-24 2004-01-29 Ritchart Mark A. Methods and devices for automated biopsy and collection of soft tissue
US5649547A (en) * 1994-03-24 1997-07-22 Biopsys Medical, Inc. Methods and devices for automated biopsy and collection of soft tissue
US5980469A (en) * 1994-03-24 1999-11-09 Ethicon Endo-Surgery, Inc. Method and apparatus for automated biopsy and collection of soft tissue
US5928164A (en) * 1994-03-24 1999-07-27 Ethicon Endo-Surgery, Inc. Apparatus for automated biopsy and collection of soft tissue
US5775333A (en) * 1994-03-24 1998-07-07 Ethicon Endo-Surgery, Inc. Apparatus for automated biopsy and collection of soft tissue
US5997560A (en) * 1994-07-21 1999-12-07 Sdgi Holdings, Inc. Surgical cutting instrument
US5595185A (en) * 1994-08-11 1997-01-21 N.M.B. Medical Applications Ltd. Single puncture multi-biopsy gun
US5954670A (en) * 1994-10-05 1999-09-21 Baker; Gary H. Mandrel-guided tandem multiple channel biopsy guide device and method of use
US5538010A (en) * 1994-10-05 1996-07-23 Proact Ltd. Biopsy needle device
US5578030A (en) * 1994-11-04 1996-11-26 Levin; John M. Biopsy needle with cauterization feature
US6036681A (en) * 1995-02-10 2000-03-14 Enable Medical Corporation Apparatus and method for morselating and removing tissue from a patient
US5814044A (en) * 1995-02-10 1998-09-29 Enable Medical Corporation Apparatus and method for morselating and removing tissue from a patient
US5947964A (en) * 1995-03-03 1999-09-07 Neothermia Corporation Methods and apparatus for therapeutic cauterization of predetermined volumes of biological tissue
US5857982A (en) * 1995-09-08 1999-01-12 United States Surgical Corporation Apparatus and method for removing tissue
US5857981A (en) * 1995-09-12 1999-01-12 Bucalo; Brian D. Biopsy instrument with tissue specimen retaining and retrieval device
US5782775A (en) * 1995-10-20 1998-07-21 United States Surgical Corporation Apparatus and method for localizing and removing tissue
US5848978A (en) * 1995-11-14 1998-12-15 Genx International, Inc. Surgical biopsy device
US5687739A (en) * 1995-12-06 1997-11-18 Interventional Concepts, Inc. Biopsy specimen cutter
US5769086A (en) * 1995-12-06 1998-06-23 Biopsys Medical, Inc. Control system and method for automated biopsy device
US5925044A (en) * 1996-07-01 1999-07-20 Gebrueder Berchtold Gmbh & Co. Trocar for laparoscopic operations
US5913857A (en) * 1996-08-29 1999-06-22 Ethicon End0-Surgery, Inc. Methods and devices for collection of soft tissue
US5810806A (en) * 1996-08-29 1998-09-22 Ethicon Endo-Surgery Methods and devices for collection of soft tissue
US5882316A (en) * 1996-08-29 1999-03-16 City Of Hope Minimally invasive biopsy device
US5876340A (en) * 1997-04-17 1999-03-02 Irvine Biomedical, Inc. Ablation apparatus with ultrasonic imaging capabilities
US5846513A (en) * 1997-07-08 1998-12-08 Carewise Medical Products Corporation Tumor localization and removal system using penetratable detection probe and removal instrument
US5846513B1 (en) * 1997-07-08 2000-11-28 Carewise Medical Products Corp Tumor localization and removal system using penetratable detection probe and removal instrument
US6142955A (en) * 1997-09-19 2000-11-07 United States Surgical Corporation Biopsy apparatus and method
US6050955A (en) * 1997-09-19 2000-04-18 United States Surgical Corporation Biopsy apparatus and method
US20030004407A1 (en) * 1997-11-18 2003-01-02 Carewise Medical Products Corporation Minimally invasive surgical
US6261241B1 (en) * 1998-03-03 2001-07-17 Senorx, Inc. Electrosurgical biopsy device and method
US6540695B1 (en) * 1998-04-08 2003-04-01 Senorx, Inc. Biopsy anchor device with cutter
US5964716A (en) * 1998-05-14 1999-10-12 Ethicon Endo-Surgery, Inc. Method of use for a multi-port biopsy instrument
US6258000B1 (en) * 1998-05-21 2001-07-10 Liechty, Ii Victor Jay Penetration enhancing aerodynamically favorable arrowhead
US6086543A (en) * 1998-06-24 2000-07-11 Rubicor Medical, Inc. Fine needle and core biopsy devices and methods
US6312429B1 (en) * 1998-09-01 2001-11-06 Senorx, Inc. Electrosurgical lesion location device
US6689145B2 (en) * 1998-09-03 2004-02-10 Rubicor Medical, Inc. Excisional biopsy devices and methods
US6056700A (en) * 1998-10-13 2000-05-02 Emx, Inc. Biopsy marker assembly and method of use
US6120462A (en) * 1999-03-31 2000-09-19 Ethicon Endo-Surgery, Inc. Control method for an automated surgical biopsy device
US6514215B1 (en) * 1999-10-13 2003-02-04 Pentax Corporation Endoscopic tissue collecting instrument
US6514248B1 (en) * 1999-10-15 2003-02-04 Neothermia Corporation Accurate cutting about and into tissue volumes with electrosurgically deployed electrodes
US6277083B1 (en) * 1999-12-27 2001-08-21 Neothermia Corporation Minimally invasive intact recovery of tissue
US6758824B1 (en) * 2000-11-06 2004-07-06 Suros Surgical Systems, Inc. Biopsy apparatus
US6835173B2 (en) * 2001-10-05 2004-12-28 Scimed Life Systems, Inc. Robotic endoscope
US20030125639A1 (en) * 2002-01-02 2003-07-03 Fisher John S. Biopsy needle having rotating core for shearing tissue
US7189206B2 (en) * 2003-02-24 2007-03-13 Senorx, Inc. Biopsy device with inner cutter

Cited By (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9421002B2 (en) 2002-03-19 2016-08-23 C. R. Bard, Inc. Disposable biopsy unit
US9439631B2 (en) 2002-03-19 2016-09-13 C. R. Bard, Inc. Biopsy device and insertable biopsy needle module
US9072502B2 (en) 2002-03-19 2015-07-07 C. R. Bard, Inc. Disposable biopsy unit
US8951209B2 (en) 2002-03-19 2015-02-10 C. R. Bard, Inc. Biopsy device and insertable biopsy needle module
US11382608B2 (en) 2002-03-19 2022-07-12 C. R. Bard, Inc. Disposable biopsy unit
US10271827B2 (en) 2002-03-19 2019-04-30 C. R. Bard, Inc. Disposable biopsy unit
US8002713B2 (en) 2002-03-19 2011-08-23 C. R. Bard, Inc. Biopsy device and insertable biopsy needle module
US10335128B2 (en) 2002-03-19 2019-07-02 C. R. Bard, Inc. Biopsy device and insertable biopsy needle module
US8016772B2 (en) 2002-03-19 2011-09-13 C. R. Bard, Inc. Biopsy device for removing tissue specimens using a vacuum
US8052614B2 (en) 2002-03-19 2011-11-08 C. R. Bard, Inc. Biopsy device having a vacuum pump
US8172773B2 (en) 2002-03-19 2012-05-08 C. R. Bard, Inc. Biopsy device and biopsy needle module that can be inserted into the biopsy device
US8109885B2 (en) 2002-03-19 2012-02-07 C. R. Bard, Inc. Biopsy device for removing tissue specimens using a vacuum
US8162851B2 (en) 2003-03-29 2012-04-24 C. R. Bard, Inc. Biopsy needle system having a pressure generating unit
US8728004B2 (en) 2003-03-29 2014-05-20 C.R. Bard, Inc. Biopsy needle system having a pressure generating unit
US10166011B2 (en) 2004-07-09 2019-01-01 Bard Peripheral Vascular, Inc. Transport system for biopsy device
US8366636B2 (en) 2004-07-09 2013-02-05 Bard Peripheral Vascular, Inc. Firing system for biopsy device
US9345458B2 (en) 2004-07-09 2016-05-24 Bard Peripheral Vascular, Inc. Transport system for biopsy device
US9456809B2 (en) 2004-07-09 2016-10-04 Bard Peripheral Vascular, Inc. Tissue sample flushing system for biopsy device
US8157744B2 (en) 2004-07-09 2012-04-17 Bard Peripheral Vascular, Inc. Tissue sample flushing system for biopsy device
US8992440B2 (en) 2004-07-09 2015-03-31 Bard Peripheral Vascular, Inc. Length detection system for biopsy device
US8926527B2 (en) 2004-07-09 2015-01-06 Bard Peripheral Vascular, Inc. Tissue sample flushing system for biopsy device
US8864680B2 (en) 2004-07-09 2014-10-21 Bard Peripheral Vascular, Inc. Transport system for biopsy device
US9872672B2 (en) 2004-07-09 2018-01-23 Bard Peripheral Vascular, Inc. Length detection system for biopsy device
US8052615B2 (en) 2004-07-09 2011-11-08 Bard Peripheral Vascular, Inc. Length detection system for biopsy device
US10499888B2 (en) 2004-07-09 2019-12-10 Bard Peripheral Vascular, Inc. Tissue sample flushing system for biopsy device
US11166702B2 (en) 2005-01-31 2021-11-09 C.R. Bard, Inc. Quick cycle biopsy system
US10058308B2 (en) 2005-01-31 2018-08-28 C. R. Bard, Inc. Method for operating a biopsy apparatus
US8702621B2 (en) 2005-01-31 2014-04-22 C.R. Bard, Inc. Quick cycle biopsy system
US8012102B2 (en) 2005-01-31 2011-09-06 C. R. Bard, Inc. Quick cycle biopsy system
US9161743B2 (en) 2005-01-31 2015-10-20 C. R. Bard, Inc. Quick cycle biopsy system
US8702622B2 (en) 2005-01-31 2014-04-22 C.R. Bard, Inc. Quick cycle biopsy system
US20070060935A1 (en) * 2005-07-11 2007-03-15 Schwardt Jeffrey D Apparatus and methods of tissue removal within a spine
US8721563B2 (en) 2005-08-10 2014-05-13 C. R. Bard, Inc. Single-insertion, multiple sample biopsy device with integrated markers
US8262585B2 (en) 2005-08-10 2012-09-11 C. R. Bard, Inc. Single-insertion, multiple sampling biopsy device with linear drive
US11849928B2 (en) 2005-08-10 2023-12-26 C. R. Bard, Inc. Single-insertion, multiple sampling biopsy device usable with various transport systems and integrated markers
US8282574B2 (en) 2005-08-10 2012-10-09 C. R. Bard, Inc. Single-insertion, multiple sampling biopsy device usable with various transport systems and integrated markers
US8267868B2 (en) 2005-08-10 2012-09-18 C. R. Bard, Inc. Single-insertion, multiple sample biopsy device with integrated markers
US10368849B2 (en) 2005-08-10 2019-08-06 C. R. Bard, Inc. Single-insertion, multiple sampling biopsy device usable with various transport systems and integrated markers
US8771200B2 (en) 2005-08-10 2014-07-08 C.R. Bard, Inc. Single insertion, multiple sampling biopsy device with linear drive
US8961430B2 (en) 2005-08-10 2015-02-24 C.R. Bard, Inc. Single-insertion, multiple sampling biopsy device usable with various transport systems and integrated markers
US10010307B2 (en) 2005-08-10 2018-07-03 C. R. Bard, Inc. Single-insertion, multiple sampling biopsy device with linear drive
US11219431B2 (en) 2005-08-10 2022-01-11 C.R. Bard, Inc. Single-insertion, multiple sampling biopsy device with linear drive
US8728003B2 (en) 2005-08-10 2014-05-20 C.R. Bard Inc. Single insertion, multiple sample biopsy device with integrated markers
US8951208B2 (en) 2006-08-21 2015-02-10 C. R. Bard, Inc. Self-contained handheld biopsy needle
US10617399B2 (en) 2006-08-21 2020-04-14 C.R. Bard, Inc. Self-contained handheld biopsy needle
US8251917B2 (en) 2006-08-21 2012-08-28 C. R. Bard, Inc. Self-contained handheld biopsy needle
US9566045B2 (en) 2006-10-06 2017-02-14 Bard Peripheral Vascular, Inc. Tissue handling system with reduced operator exposure
US10172594B2 (en) 2006-10-06 2019-01-08 Bard Peripheral Vascular, Inc. Tissue handling system with reduced operator exposure
US11559289B2 (en) 2006-10-06 2023-01-24 Bard Peripheral Vascular, Inc. Tissue handling system with reduced operator exposure
US8485987B2 (en) 2006-10-06 2013-07-16 Bard Peripheral Vascular, Inc. Tissue handling system with reduced operator exposure
US10149664B2 (en) 2006-10-24 2018-12-11 C. R. Bard, Inc. Large sample low aspect ratio biopsy needle
US8262586B2 (en) 2006-10-24 2012-09-11 C. R. Bard, Inc. Large sample low aspect ratio biopsy needle
US11583261B2 (en) 2006-10-24 2023-02-21 C. R. Bard, Inc. Large sample low aspect ratio biopsy needle
US9775588B2 (en) 2007-12-20 2017-10-03 C. R. Bard, Inc. Biopsy device
US8858463B2 (en) 2007-12-20 2014-10-14 C. R. Bard, Inc. Biopsy device
US10687791B2 (en) 2007-12-20 2020-06-23 C. R. Bard, Inc. Biopsy device
US8454532B2 (en) 2007-12-27 2013-06-04 Devicor Medical Products, Inc. Clutch and valving system for tetherless biopsy device
US8864682B2 (en) 2007-12-27 2014-10-21 Devicor Medical Products, Inc. Clutch and valving system for tetherless biopsy device
US20090270892A1 (en) * 2008-04-25 2009-10-29 Greg Arcenio Steerable medical device for tissue disruption
US20090270862A1 (en) * 2008-04-25 2009-10-29 Greg Arcenio Medical device with one-way rotary drive mechanism
US20090270893A1 (en) * 2008-04-25 2009-10-29 Greg Arcenio Medical device for tissue disruption with serrated expandable portion
US20100030216A1 (en) * 2008-07-30 2010-02-04 Arcenio Gregory B Discectomy tool having counter-rotating nucleus disruptors
US8690793B2 (en) 2009-03-16 2014-04-08 C. R. Bard, Inc. Biopsy device having rotational cutting
US8708928B2 (en) 2009-04-15 2014-04-29 Bard Peripheral Vascular, Inc. Biopsy apparatus having integrated fluid management
US8708930B2 (en) 2009-04-15 2014-04-29 Bard Peripheral Vascular, Inc. Biopsy apparatus having integrated fluid management
US8708929B2 (en) 2009-04-15 2014-04-29 Bard Peripheral Vascular, Inc. Biopsy apparatus having integrated fluid management
US8845548B2 (en) 2009-06-12 2014-09-30 Devicor Medical Products, Inc. Cutter drive assembly for biopsy device
US9468424B2 (en) 2009-06-12 2016-10-18 Devicor Medical Products, Inc. Cutter drive assembly for biopsy device
US9173641B2 (en) 2009-08-12 2015-11-03 C. R. Bard, Inc. Biopsy apparatus having integrated thumbwheel mechanism for manual rotation of biopsy cannula
US9655599B2 (en) 2009-08-12 2017-05-23 C. R. Bard, Inc. Biopsy apparatus having integrated thumbwheel mechanism for manual rotation of biopsy cannula
US10575833B2 (en) 2009-08-12 2020-03-03 C. R. Bard, Inc. Biopsy apparatus having integrated thumbwheel mechanism for manual rotation of biopsy cannula
US9949726B2 (en) 2009-09-01 2018-04-24 Bard Peripheral Vscular, Inc. Biopsy driver assembly having a control circuit for conserving battery power
US9282949B2 (en) 2009-09-01 2016-03-15 Bard Peripheral Vascular, Inc. Charging station for battery powered biopsy apparatus
US8485989B2 (en) 2009-09-01 2013-07-16 Bard Peripheral Vascular, Inc. Biopsy apparatus having a tissue sample retrieval mechanism
US8283890B2 (en) 2009-09-25 2012-10-09 Bard Peripheral Vascular, Inc. Charging station for battery powered biopsy apparatus
USD640977S1 (en) 2009-09-25 2011-07-05 C. R. Bard, Inc. Charging station for a battery operated biopsy device
US8597206B2 (en) 2009-10-12 2013-12-03 Bard Peripheral Vascular, Inc. Biopsy probe assembly having a mechanism to prevent misalignment of components prior to installation
US8430824B2 (en) 2009-10-29 2013-04-30 Bard Peripheral Vascular, Inc. Biopsy driver assembly having a control circuit for conserving battery power
US8808197B2 (en) 2009-10-29 2014-08-19 Bard Peripheral Vascular, Inc. Biopsy driver assembly having a control circuit for conserving battery power
US8858461B2 (en) * 2010-11-19 2014-10-14 Jean-Charles Persat Tissue sampling tool, in particular for adipose tissue
US20120130274A1 (en) * 2010-11-19 2012-05-24 Jean-Charles Persat Tissue sampling tool, in particular for adipose tissue
US9226734B2 (en) * 2011-03-24 2016-01-05 Cook Medical Technologies Llc Closed side-sampling biopsy device
US20120245487A1 (en) * 2011-03-24 2012-09-27 Robert Eells Closed side-sampling biopsy device
US11026665B2 (en) 2011-11-09 2021-06-08 Teesuvac Aps Handheld tissue sample extraction device
US9943293B2 (en) 2011-11-09 2018-04-17 Teesuvac Aps Handheld tissue sample extraction device
US10285673B2 (en) 2013-03-20 2019-05-14 Bard Peripheral Vascular, Inc. Biopsy device
US11779316B2 (en) 2013-03-20 2023-10-10 Bard Peripheral Vascular, Inc. Biopsy device
US10456120B2 (en) 2013-11-05 2019-10-29 C. R. Bard, Inc. Biopsy device having integrated vacuum
US11534148B2 (en) 2013-11-05 2022-12-27 C. R. Bard, Inc. Biopsy device having integrated vacuum
US10463350B2 (en) 2015-05-01 2019-11-05 C. R. Bard, Inc. Biopsy device
US11179142B2 (en) 2015-05-01 2021-11-23 C.R. Bard, Inc. Biopsy device
WO2017023674A1 (en) * 2015-07-31 2017-02-09 Polygon Medical, Inc. Polypectomy systems, devices, and methods
US9707012B2 (en) 2015-07-31 2017-07-18 Polygon Medical, Inc. Polypectomy systems, devices, and methods
US11116483B2 (en) 2017-05-19 2021-09-14 Merit Medical Systems, Inc. Rotating biopsy needle
US11793498B2 (en) 2017-05-19 2023-10-24 Merit Medical Systems, Inc. Biopsy needle devices and methods of use
US11844500B2 (en) 2017-05-19 2023-12-19 Merit Medical Systems, Inc. Semi-automatic biopsy needle device and methods of use
US11278320B2 (en) 2017-06-14 2022-03-22 Polygon Medical, Inc. Polypectomy systems, devices, and methods
US10285731B2 (en) 2017-06-14 2019-05-14 Polygon Medical, Inc. Polypectomy systems, devices, and methods
USD947378S1 (en) 2017-06-27 2022-03-29 Polygon Medical, Inc. Medical device handle
USD847992S1 (en) 2017-06-27 2019-05-07 Polygon Medical, Inc. Medical device handle

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CA2766257A1 (en) 2004-09-10
US10172595B2 (en) 2019-01-08
US20080319468A1 (en) 2008-12-25
US20190133562A1 (en) 2019-05-09
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US20150230778A1 (en) 2015-08-20
US8460204B2 (en) 2013-06-11
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US7819819B2 (en) 2010-10-26
US10231715B2 (en) 2019-03-19
US11534147B2 (en) 2022-12-27
US20100262037A1 (en) 2010-10-14
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US7189206B2 (en) 2007-03-13
US20140039344A1 (en) 2014-02-06
US20100268117A1 (en) 2010-10-21
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US20040167428A1 (en) 2004-08-26
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US20040167427A1 (en) 2004-08-26
US10335127B2 (en) 2019-07-02
US9204866B2 (en) 2015-12-08
CA2926638A1 (en) 2004-09-10
CA2926638C (en) 2020-05-05
US20080319342A1 (en) 2008-12-25
EP2649946B1 (en) 2020-01-15
US9044215B2 (en) 2015-06-02

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