US20060025763A1 - Ablation catheter with cooled linear electrode - Google Patents

Ablation catheter with cooled linear electrode Download PDF

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Publication number
US20060025763A1
US20060025763A1 US11/235,462 US23546205A US2006025763A1 US 20060025763 A1 US20060025763 A1 US 20060025763A1 US 23546205 A US23546205 A US 23546205A US 2006025763 A1 US2006025763 A1 US 2006025763A1
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United States
Prior art keywords
catheter
electrode
electrode assembly
catheter tube
comprised
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US11/235,462
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Dale Nelson
Steven Savage
William Penny
Jeffrey Santer
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Biosense Webster Inc
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Biosense Webster Inc
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Priority to US11/235,462 priority Critical patent/US20060025763A1/en
Assigned to BIOSENSE WEBSTER, INC. reassignment BIOSENSE WEBSTER, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: NELSON, DALE, SANTER, JEFFREY, PENNY, WILLIAM, SAVAGE, STEVEN D.
Publication of US20060025763A1 publication Critical patent/US20060025763A1/en
Abandoned legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00292—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
    • A61B2017/003—Steerable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
    • A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
    • A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
    • A61B2018/00029—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids open
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00059—Material properties
    • A61B2018/00065—Material properties porous
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345—Vascular system
    • A61B2018/00351—Heart
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577—Ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1405—Electrodes having a specific shape
    • A61B2018/1407—Loop
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2218/00—Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2218/001—Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body having means for irrigation and/or aspiration of substances to and/or from the surgical site
    • A61B2218/002—Irrigation

Definitions

  • This invention relates generally to a cardiac catheter used for performing cardiovascular procedures on the heart. More particularly, this invention relates to an ablation catheter used predominantly for treating cardiac arrhythmias.
  • Radio frequency ablation has become a common treatment for treating specific cardiac arrhythmias. Portions of the heart sometimes form alternative conduction pathways which interfere with the normal conduction of the electrical signals which regulate the beating of the heart thereby causing some cardiac arrhythmias to occur.
  • the heart is first mapped through catheter mapping procedures in order to find where these alternative conduction pathways are located, and then RFA is used to prevent these areas of the heart from disrupting the normal conduction patterns of the heart.
  • RFA typically involves the use of a specialized ablation catheter which is positioned at the site of the alternative conduction pathway.
  • Radio frequency (RF) waves are then typically delivered through the ablation catheter and onto the alternative conduction pathway.
  • the radio frequency waves create heat at the site of the alternative conduction pathway creating a lesion which destroys the tissues forming the alternative conduction pathways.
  • Ablation catheters have been developed in order to deliver radio frequency waves at the site of the abnormal pathway. While some of these prior art ablation catheters are well suited for particular procedures, the ability of these prior art ablation catheters to perform a variety of procedures effectively have been limited due to a number structural constraints which are necessitated by the spatial and physiological requirements of the applications in which these ablation catheters are to be used. Size, flexibility, and maneuverability are common restraints which have previously prevented more effective ablation catheter designs.
  • One drawback to the prior art is their inability to make a variety of lesions.
  • One type of lesion is a focal lesion where the RF wave is concentrated at a point.
  • the prior art is limited to making focal lesions.
  • a tip electrode carried on the distal tip of an ablation catheter is preferably used for making focal lesions.
  • linear lesions there are a variety of procedures in which linear lesions are preferred requiring that the RF energy be delivered along a line.
  • a linear electrode is preferably utilized for making linear lesions.
  • tip electrodes can also be used utilized for making linear lesions, the use of tip electrodes to make linear lesions can be significantly more difficult and time consuming.
  • the maneuverability of the prior art ablation catheters also limit their effectiveness.
  • the ablation catheters are typically utilized within the interior chambers of the heart.
  • the precise placement of the electrodes onto the site to which the RF waves are to be delivered and the sufficiency of the contact between an electrode and the site significantly impacts the effectiveness of the treatment.
  • Linear electrodes, and especially longer linear electrodes tend to be stiffer, making it more difficult for them to maneuver and to conform to the generally arcuate shape of the interior walls of the heart.
  • an object of this invention to provide an ablation catheter which is capable of generating both focal lesions and linear lesions while having the appropriate size, flexibility and maneuverability to enable it to be used effectively in a variety of RFA procedures.
  • an object of this invention to provide for an ablation catheter with a linear electrode which is easily maneuverable and conforms readily to the arcuate shape of the interior of the heart while still having the appropriate size, flexibility and maneuverability to enable the ablation catheter to be used effectively in a variety of RFA procedures.
  • an ablation catheter with a means for cooling the electrode in order to reduce the rate at which the coagulum builds up on the surface of an electrode while still having the appropriate size, flexibility and maneuverability to enable it to be used effectively in most RFA procedures.
  • the present invention provides the aforementioned and employs a number of novel features that render it highly advantageous over the prior art.
  • an ablation catheter which comprises two major components, an articulating guiding catheter and an inner articulating catheter disposed therein.
  • the guiding catheter is typically inserted into the vascular system and is guided and manipulated through the vascular system until it reaches the appropriate chamber of the heart.
  • the inner catheter is disposed within the guiding catheter until a desired location in the heart is reached. At that point the inner catheter is then extended beyond the guiding catheter allowing the inner catheter to more precisely position itself onto a treatment site.
  • the guiding catheter is comprised of a shaft section which is attached to an articulating section at its distal end and a first handle at its proximal end.
  • the inner catheter is comprised of an elongated central shaft, an electrode assembly attached to the distal end of the central shaft, and a second handle attached to the proximal end of the central shaft.
  • the electrode assembly is comprised of a flexible plastic catheter tube having an outer surface, a porous tip electrode, and at least one linear electrode carried on the outer surface of the catheter tube.
  • the catheter tube is used to provide axial and radial stability to the electrode assembly and to provide a conduit to the electrode assembly. Fluid is distributed to the linear electrode and the porous tip electrode through a plurality of apertures extending from the inner surface of the catheter tube to the outer surface of the catheter tube.
  • the linear electrode is utilized in order to make linear lesions in the heart tissue.
  • the linear electrode is comprised of a tubular array of conductive metal strands carried on the outer surface of the catheter tube, the conductive strands extending along the catheter tube in a plurality of directions relative to the longitudinal axis of the catheter tube.
  • the tubular array of metal strands is a wound helical coil.
  • the tubular array of metal strands is arranged in a braided construction.
  • the porous tip electrode is located at the distal end of the electrode assembly. The tip electrode provides a means for creating lesions concentrated at particular points in the heart, otherwise called focal lesions.
  • Articulation of the electrode assembly is utilized in order to better align the linear electrode to the generally arcuate shape of the inner chambers of the heart.
  • One means for articulating the electrode assembly is by extending a pull wire through the inner catheter and attaching it to the distal tip of the catheter tube.
  • An alternate means for articulating the electrode assembly is achieved by running the pull wire through the inner catheter, then having the wire run externally along the linear electrode, and then finally attaching the pull wire to the distal tip of the electrode assembly.
  • a second alternate means for articulating the electrode assembly is achieved through the use of a memory shaped tube which is thermally activated to conform to a predetermined shape upon reaching body temperature.
  • FIG. 1 is a planar view of an ablation catheter embodying features in accordance with the present invention.
  • FIG. 2 is a side section view of the distal portion of the ablation catheter shown in FIG. 1 providing an enlarged view of the electrode assembly.
  • FIG. 3 is a side view of a linear electrode assembly having helically wound coils.
  • FIG. 4 is a side view of a linear electrode assembly having a braided construction.
  • FIG. 5 is a side section view of a linear electrode assembly utilizing coils made of hypodermic tubing.
  • FIG. 6 is a side section view of a linear electrode assembly utilizing coils made of a combination of hypodermic tubing and solid wire.
  • FIG. 7 is a side section view of a linear electrode assembly with added monitoring capabilities.
  • FIG. 8 is side section view of a linear electrode assembly having an articulating means.
  • FIG. 9 is a side section view of a linear electrode assembly having an exterior articulating means.
  • FIG. 10 is side section view of a linear electrode assembly having a thermally activated alternative articulating means.
  • an ablation catheter is comprised of two major components, an articulating guiding catheter 10 and an inner articulating catheter 50 disposed therein.
  • the guiding catheter 10 is typically inserted into the vascular system and is guided and manipulated through the vascular system until it reaches the appropriate chamber of the heart. Once positioned within the heart, the guiding catheter 10 provides a uniform conduit for introducing the inner catheter 50 into the chambers of the heart.
  • the inner catheter 50 is disposed within the guiding catheter and typically travels within the guiding catheter until a desired location in the heart is reached. At that point the inner catheter 50 is then extended beyond the guiding catheter 10 allowing the inner catheter 50 to more precisely position itself onto a treatment site.
  • the guiding catheter 10 is comprised of a shaft section 12 having an articulating section 19 at its distal end and a first handle 14 attached at its proximal end.
  • a plurality of ring electrodes 13 is carried on the distal end of the guiding catheter 10 .
  • the ring electrodes 13 when in contact with the heart tissue, are able to take measurements of endocardial potentials.
  • the shaft 12 is comprised of preferably constructed of an inner and outer layer of plastic which encapsulate a braided metal, but other means of constructing the shaft would work suitably with the present invention.
  • the handle 14 is comprised of a first mechanism for articulating 17 the articulating section 19 , an interface for electricity 15 , a first fluid interface 16 , and an interface for inserting 18 the inner articulating catheter 50 . It should be understood that various additional interfaces can be incorporated in the guiding catheter.
  • the inner catheter 50 is comprised of an elongated central shaft 53 , an electrode assembly 54 attached to the distal end of the central shaft, and a second handle 56 attached to the proximal end of the central shaft 53 .
  • the inner catheter is removably disposed within the guiding catheter, allowing the inner catheter to be removed and reinserted into the guiding catheter a number of times during a medical procedure.
  • the second handle 56 is comprised of a second mechanism 55 for articulating the distal end of the inner catheter 50 , an RF interface 58 for connecting the inner catheter 50 to an RF generator, and a second fluid inter face 57 .
  • the second fluid interface is connected to a separate lumen within the inner catheter that extends to the distal end of the inner catheter, providing a conduit for fluids from the second fluid interface to the electrode assembly 54 . It should also be understood that various additional interfaces can be incorporated in the inner catheter design.
  • the electrode assembly 54 is comprised of a flexible plastic catheter tube 60 having an outer surface, a porous tip electrode 52 attached on the outer surface at the distal end of the catheter tube 60 , and at least one linear electrode 61 carried on the outer surface of the catheter tube 60 .
  • the catheter tube 60 is used to provide axial and radial stability to the electrode assembly and to provide a conduit for the flow of fluid to cool the linear electrode 61 and tip electrode 52 .
  • the catheter tube 60 is preferably a thin walled, non conductive, single lumen tube constructed of a flexible polymer plastic. Fluid received from the second fluid interface flows through the inner catheter 50 to the catheter tube 60 . There the fluid is distributed to the linear electrode 61 and the tip electrode 52 through a plurality of apertures 62 extending from the inner surface of the catheter tube 60 to the outer surface of the catheter tube 60 . The apertures 62 are spaced to allow for uniform flow of fluid to all parts of the linear electrode 61 and the porous tip electrode 52 .
  • “hot spots” may develop on sections of an electrode if there is not enough fluid flow reaching the area. Since fluid is being uniformly delivered to all sections of the linear electrode 61 and tip electrode 52 through the catheter tube 60 , the chances for a “hot spot” to develop is minimized or eliminated.
  • the linear electrode 61 is utilized in order to make linear lesions in the heart tissue.
  • the linear electrode can be attached either to the elongated central shaft 53 or the catheter tube 60 .
  • Conductive wire connects the linear electrode to the RF interface 58 .
  • the linear electrode 61 is comprised of a tubular array of conductive metal strands carried on the outer surface of the catheter tube 60 , the conductive strands extending along the catheter tube 60 in a plurality of directions relative to the longitudinal axis of the catheter tube 60 .
  • the conductive strands are preferably made from rounded or flat solid wire 311 , or hypodermic tubing 300 , or a combination of both as shown in FIG. 5 and 6 .
  • Hypodermic tubing has the advantage of enabling the linear electrode 61 to be cooled by circulating fluid within the hypodermic tubing as well as from fluid flow from the apertures 62 in the catheter tube 60 .
  • the tubular array of metal strands is a wound helical coil 200 .
  • the spacing between loops in the coil is varied in order to achieve different physiological effects.
  • the loops can be wound tightly with each loop in the coil in contact with its neighboring loops as in FIG. 3 or the loops can be wound loosely as in FIG. 5 .
  • a tight spacing of the loops in the coil will enable the linear electrode 61 to deliver a higher energy density, but may increase the stiffness of the linear electrode and may increase parasitic power loss. Greater spacing between the loops in the coil will provide more flexibility and less power loss.
  • the tubular array of metal strands is arranged in a braided construction 201 .
  • additional monitoring electrodes 401 can be placed onto the linear electrode 61 .
  • the monitoring electrodes would preferably rest on an insulating sleeve 402 electrically isolated from the linear electrode.
  • the monitoring electrodes are preferably cylindrical metallic bands 401 .
  • the metallic bands 401 are coupled to physiological monitoring equipment through a wire 403 extending from the metallic band and through the inner catheter.
  • the porous tip electrode 52 is located at the distal end of the electrode assembly 54 .
  • the porous tip electrode 52 provides the inner catheter 50 a means for creating lesions concentrated at particular points in the heart, otherwise called focal lesions.
  • RF energy is supplied to the porous tip electrode through a conductor wire 65 which extends from the tip electrode 52 to the RF interface 58 in the second handle 56 .
  • articulation of the electrode assembly is utilized in order to better align the linear electrode 61 to the generally arcuate shape of the inner chambers of the heart.
  • One means for articulating the electrode assembly is by extending a pull wire 501 from the second mechanism for articulating 55 through the inner catheter 50 and attaching it to the distal tip of the catheter tube 60 . Creating a pulling motion on the pull wire 501 by means of the second mechanism for articulating 55 will cause the distal end of the catheter tube 60 to deflect towards the direction of the pulling motion.
  • a stiffener can be used in this configuration in order to return the electrode assembly 54 back to its original position.
  • an alternate means for articulating the electrode assembly is achieved by running the pull wire 501 from the second mechanism for articulating 55 through the inner catheter 50 , then having the wire run externally along the linear electrode, and then finally attaching the pull wire 501 to the distal tip of the electrode assembly 54 .
  • a second alternate means for articulating the electrode assembly is achieved through the use of a memory shaped tube 702 which is thermally activated to conform to a predetermined shape.
  • NitinolTM tubing or other materials having thermally activated shape memory characteristics can be used for the catheter tube 60 .
  • the catheter tube would remain relatively erectile during the positioning of the electrode assembly 54 , but once the RF energy is applied, the thermal energy would cause the NitinolTM tubing to deflect into an arcuate shape.
  • This means for articulation has the advantage of not requiring the use of pull wires 501 or mechanisms for articulating.

Abstract

The ablation catheter is comprised of a guiding catheter and an inner catheter. The guiding catheter is comprised of a shaft section which is attached to an articulating section at its distal end and a first handle at its proximal end. The inner catheter is comprised of an elongated central shaft, an electrode assembly attached to the distal end of the central shaft, and a second handle attached to the proximal end of the central shaft. The electrode assembly is comprised of a flexible plastic catheter tube having an outer surface, a porous tip electrode, and at least one linear electrode carried on the outer surface of the catheter tube. The electrode assembly is articulated to better align the electrode assembly to the generally arcuate shape of the inner chambers of the heart.

Description

  • This is a division of application Ser. No. 10/657,647, filed Sep. 8, 2003, which is a division of application Ser. No. 09/642,202 filed Aug. 21, 2000.
    • FIELD OF THE INVENTION
  • This invention relates generally to a cardiac catheter used for performing cardiovascular procedures on the heart. More particularly, this invention relates to an ablation catheter used predominantly for treating cardiac arrhythmias.
    • BACKGROUND OF THE INVENTION
  • Radio frequency ablation (RFA) has become a common treatment for treating specific cardiac arrhythmias. Portions of the heart sometimes form alternative conduction pathways which interfere with the normal conduction of the electrical signals which regulate the beating of the heart thereby causing some cardiac arrhythmias to occur. In order to remove these alternative conduction pathways, the heart is first mapped through catheter mapping procedures in order to find where these alternative conduction pathways are located, and then RFA is used to prevent these areas of the heart from disrupting the normal conduction patterns of the heart.
  • RFA typically involves the use of a specialized ablation catheter which is positioned at the site of the alternative conduction pathway. Radio frequency (RF) waves are then typically delivered through the ablation catheter and onto the alternative conduction pathway. The radio frequency waves create heat at the site of the alternative conduction pathway creating a lesion which destroys the tissues forming the alternative conduction pathways.
  • Ablation catheters have been developed in order to deliver radio frequency waves at the site of the abnormal pathway. While some of these prior art ablation catheters are well suited for particular procedures, the ability of these prior art ablation catheters to perform a variety of procedures effectively have been limited due to a number structural constraints which are necessitated by the spatial and physiological requirements of the applications in which these ablation catheters are to be used. Size, flexibility, and maneuverability are common restraints which have previously prevented more effective ablation catheter designs.
  • One drawback to the prior art is their inability to make a variety of lesions. There are typically two types of lesions which are generated by ablation catheters. One type of lesion is a focal lesion where the RF wave is concentrated at a point. Typically, the prior art is limited to making focal lesions. A tip electrode carried on the distal tip of an ablation catheter is preferably used for making focal lesions. However, there are a variety of procedures in which linear lesions are preferred requiring that the RF energy be delivered along a line. There are prior art ablation catheters which are capable of creating linear lesions; however, these prior art ablation catheters are not particularly suited for making focal lesions. A linear electrode is preferably utilized for making linear lesions. Although tip electrodes can also be used utilized for making linear lesions, the use of tip electrodes to make linear lesions can be significantly more difficult and time consuming.
  • The maneuverability of the prior art ablation catheters also limit their effectiveness. The ablation catheters are typically utilized within the interior chambers of the heart. The precise placement of the electrodes onto the site to which the RF waves are to be delivered and the sufficiency of the contact between an electrode and the site significantly impacts the effectiveness of the treatment. Linear electrodes, and especially longer linear electrodes, tend to be stiffer, making it more difficult for them to maneuver and to conform to the generally arcuate shape of the interior walls of the heart.
  • Another problem common amongst the prior art ablation catheters is the formation of coagulum around the electrode during ablation. The heat generated by the RFA sometimes causes the electrode to overheat causing the blood surrounding the electrode to coagulate on the electrode. As the coagulum collects on the electrode, the impedance between the electrode and the site to which the RF wave is applied increases, thereby reducing the effectiveness of the electrode. As a result it is often necessary to stop the RFA in order to remove the coagulum from the electrode.
  • Accordingly, it is an object of this invention to provide an ablation catheter which is capable of generating both focal lesions and linear lesions while having the appropriate size, flexibility and maneuverability to enable it to be used effectively in a variety of RFA procedures.
  • Accordingly, it is also an object of this invention to provide for an ablation catheter with a linear electrode which is easily maneuverable and conforms readily to the arcuate shape of the interior of the heart while still having the appropriate size, flexibility and maneuverability to enable the ablation catheter to be used effectively in a variety of RFA procedures.
  • Accordingly, it is also a further object of this invention to provide an ablation catheter with a means for cooling the electrode in order to reduce the rate at which the coagulum builds up on the surface of an electrode while still having the appropriate size, flexibility and maneuverability to enable it to be used effectively in most RFA procedures.
  • Other objects and advantages of the invention will become apparent as the description proceeds.
  • To achieve these objectives, and in accordance with the purposes of the present invention the following ablation catheter is presented. As will be described in greater detail hereinafter, the present invention provides the aforementioned and employs a number of novel features that render it highly advantageous over the prior art.
    • SUMMARY OF THE INVENTION
  • In accordance with an illustrative embodiment of the present invention, an ablation catheter is provided which comprises two major components, an articulating guiding catheter and an inner articulating catheter disposed therein. The guiding catheter is typically inserted into the vascular system and is guided and manipulated through the vascular system until it reaches the appropriate chamber of the heart. The inner catheter is disposed within the guiding catheter until a desired location in the heart is reached. At that point the inner catheter is then extended beyond the guiding catheter allowing the inner catheter to more precisely position itself onto a treatment site.
  • In an illustrative embodiment, the guiding catheter is comprised of a shaft section which is attached to an articulating section at its distal end and a first handle at its proximal end. The inner catheter is comprised of an elongated central shaft, an electrode assembly attached to the distal end of the central shaft, and a second handle attached to the proximal end of the central shaft.
  • In one embodiment, the electrode assembly is comprised of a flexible plastic catheter tube having an outer surface, a porous tip electrode, and at least one linear electrode carried on the outer surface of the catheter tube. The catheter tube is used to provide axial and radial stability to the electrode assembly and to provide a conduit to the electrode assembly. Fluid is distributed to the linear electrode and the porous tip electrode through a plurality of apertures extending from the inner surface of the catheter tube to the outer surface of the catheter tube.
  • The linear electrode is utilized in order to make linear lesions in the heart tissue. In one embodiment, the linear electrode is comprised of a tubular array of conductive metal strands carried on the outer surface of the catheter tube, the conductive strands extending along the catheter tube in a plurality of directions relative to the longitudinal axis of the catheter tube. In one embodiment, the tubular array of metal strands is a wound helical coil. In an alternate embodiment, the tubular array of metal strands is arranged in a braided construction. The porous tip electrode is located at the distal end of the electrode assembly. The tip electrode provides a means for creating lesions concentrated at particular points in the heart, otherwise called focal lesions.
  • Articulation of the electrode assembly is utilized in order to better align the linear electrode to the generally arcuate shape of the inner chambers of the heart. One means for articulating the electrode assembly is by extending a pull wire through the inner catheter and attaching it to the distal tip of the catheter tube. An alternate means for articulating the electrode assembly is achieved by running the pull wire through the inner catheter, then having the wire run externally along the linear electrode, and then finally attaching the pull wire to the distal tip of the electrode assembly. A second alternate means for articulating the electrode assembly is achieved through the use of a memory shaped tube which is thermally activated to conform to a predetermined shape upon reaching body temperature.
  • A more detailed explanation of the invention is provided in the following description and claims, and is illustrated in the accompanying drawings.
    • DESCRIPTION OF THE DRAWINGS
  • FIG. 1 is a planar view of an ablation catheter embodying features in accordance with the present invention.
  • FIG. 2 is a side section view of the distal portion of the ablation catheter shown in FIG. 1 providing an enlarged view of the electrode assembly.
  • FIG. 3 is a side view of a linear electrode assembly having helically wound coils.
  • FIG. 4 is a side view of a linear electrode assembly having a braided construction.
  • FIG. 5 is a side section view of a linear electrode assembly utilizing coils made of hypodermic tubing.
  • FIG. 6 is a side section view of a linear electrode assembly utilizing coils made of a combination of hypodermic tubing and solid wire.
  • FIG. 7 is a side section view of a linear electrode assembly with added monitoring capabilities.
  • FIG. 8 is side section view of a linear electrode assembly having an articulating means.
  • FIG. 9 is a side section view of a linear electrode assembly having an exterior articulating means.
  • FIG. 10 is side section view of a linear electrode assembly having a thermally activated alternative articulating means.
    • DETAILED DESCRIPTION OF ILLUSTRATIVE EMBODIMENTS
  • Referring to FIG. 1, an ablation catheter is comprised of two major components, an articulating guiding catheter 10 and an inner articulating catheter 50 disposed therein. The guiding catheter 10 is typically inserted into the vascular system and is guided and manipulated through the vascular system until it reaches the appropriate chamber of the heart. Once positioned within the heart, the guiding catheter 10 provides a uniform conduit for introducing the inner catheter 50 into the chambers of the heart. The inner catheter 50 is disposed within the guiding catheter and typically travels within the guiding catheter until a desired location in the heart is reached. At that point the inner catheter 50 is then extended beyond the guiding catheter 10 allowing the inner catheter 50 to more precisely position itself onto a treatment site.
  • The guiding catheter 10 is comprised of a shaft section 12 having an articulating section 19 at its distal end and a first handle 14 attached at its proximal end. A plurality of ring electrodes 13 is carried on the distal end of the guiding catheter 10. The ring electrodes 13, when in contact with the heart tissue, are able to take measurements of endocardial potentials. The shaft 12 is comprised of preferably constructed of an inner and outer layer of plastic which encapsulate a braided metal, but other means of constructing the shaft would work suitably with the present invention. The handle 14 is comprised of a first mechanism for articulating 17 the articulating section 19, an interface for electricity 15, a first fluid interface 16, and an interface for inserting 18 the inner articulating catheter 50. It should be understood that various additional interfaces can be incorporated in the guiding catheter.
  • The inner catheter 50 is comprised of an elongated central shaft 53, an electrode assembly 54 attached to the distal end of the central shaft, and a second handle 56 attached to the proximal end of the central shaft 53. The inner catheter is removably disposed within the guiding catheter, allowing the inner catheter to be removed and reinserted into the guiding catheter a number of times during a medical procedure.
  • The second handle 56 is comprised of a second mechanism 55 for articulating the distal end of the inner catheter 50, an RF interface 58 for connecting the inner catheter 50 to an RF generator, and a second fluid inter face 57. The second fluid interface is connected to a separate lumen within the inner catheter that extends to the distal end of the inner catheter, providing a conduit for fluids from the second fluid interface to the electrode assembly 54. It should also be understood that various additional interfaces can be incorporated in the inner catheter design.
  • Referring to FIG. 2, the electrode assembly 54 is comprised of a flexible plastic catheter tube 60 having an outer surface, a porous tip electrode 52 attached on the outer surface at the distal end of the catheter tube 60, and at least one linear electrode 61 carried on the outer surface of the catheter tube 60.
  • The catheter tube 60 is used to provide axial and radial stability to the electrode assembly and to provide a conduit for the flow of fluid to cool the linear electrode 61 and tip electrode 52. The catheter tube 60 is preferably a thin walled, non conductive, single lumen tube constructed of a flexible polymer plastic. Fluid received from the second fluid interface flows through the inner catheter 50 to the catheter tube 60. There the fluid is distributed to the linear electrode 61 and the tip electrode 52 through a plurality of apertures 62 extending from the inner surface of the catheter tube 60 to the outer surface of the catheter tube 60. The apertures 62 are spaced to allow for uniform flow of fluid to all parts of the linear electrode 61 and the porous tip electrode 52. During a RFA procedure, “hot spots” may develop on sections of an electrode if there is not enough fluid flow reaching the area. Since fluid is being uniformly delivered to all sections of the linear electrode 61 and tip electrode 52 through the catheter tube 60, the chances for a “hot spot” to develop is minimized or eliminated.
  • The linear electrode 61 is utilized in order to make linear lesions in the heart tissue. The linear electrode can be attached either to the elongated central shaft 53 or the catheter tube 60. Conductive wire connects the linear electrode to the RF interface 58. The linear electrode 61 is comprised of a tubular array of conductive metal strands carried on the outer surface of the catheter tube 60, the conductive strands extending along the catheter tube 60 in a plurality of directions relative to the longitudinal axis of the catheter tube 60. The conductive strands are preferably made from rounded or flat solid wire 311, or hypodermic tubing 300, or a combination of both as shown in FIG. 5 and 6. Hypodermic tubing has the advantage of enabling the linear electrode 61 to be cooled by circulating fluid within the hypodermic tubing as well as from fluid flow from the apertures 62 in the catheter tube 60.
  • Referring to FIG. 3, in one embodiment, the tubular array of metal strands is a wound helical coil 200. The spacing between loops in the coil is varied in order to achieve different physiological effects. The loops can be wound tightly with each loop in the coil in contact with its neighboring loops as in FIG. 3 or the loops can be wound loosely as in FIG. 5. A tight spacing of the loops in the coil will enable the linear electrode 61 to deliver a higher energy density, but may increase the stiffness of the linear electrode and may increase parasitic power loss. Greater spacing between the loops in the coil will provide more flexibility and less power loss. Referring to FIG. 4 in an alternate embodiment, the tubular array of metal strands is arranged in a braided construction 201.
  • Referring to FIG. 7, in order to add more precise electrocardiac mapping capability, additional monitoring electrodes 401 can be placed onto the linear electrode 61. The monitoring electrodes would preferably rest on an insulating sleeve 402 electrically isolated from the linear electrode. The monitoring electrodes are preferably cylindrical metallic bands 401. The metallic bands 401 are coupled to physiological monitoring equipment through a wire 403 extending from the metallic band and through the inner catheter.
  • Referring to FIG. 2, the porous tip electrode 52 is located at the distal end of the electrode assembly 54. The porous tip electrode 52 provides the inner catheter 50 a means for creating lesions concentrated at particular points in the heart, otherwise called focal lesions. RF energy is supplied to the porous tip electrode through a conductor wire 65 which extends from the tip electrode 52 to the RF interface 58 in the second handle 56.
  • Referring to FIGS. 1, 2, 8 and 9, articulation of the electrode assembly is utilized in order to better align the linear electrode 61 to the generally arcuate shape of the inner chambers of the heart. One means for articulating the electrode assembly is by extending a pull wire 501 from the second mechanism for articulating 55 through the inner catheter 50 and attaching it to the distal tip of the catheter tube 60. Creating a pulling motion on the pull wire 501 by means of the second mechanism for articulating 55 will cause the distal end of the catheter tube 60 to deflect towards the direction of the pulling motion. A stiffener can be used in this configuration in order to return the electrode assembly 54 back to its original position.
  • Referring to FIG. 9, an alternate means for articulating the electrode assembly is achieved by running the pull wire 501 from the second mechanism for articulating 55 through the inner catheter 50, then having the wire run externally along the linear electrode, and then finally attaching the pull wire 501 to the distal tip of the electrode assembly 54.
  • Referring to FIG. 10, a second alternate means for articulating the electrode assembly is achieved through the use of a memory shaped tube 702 which is thermally activated to conform to a predetermined shape. Nitinol™ tubing or other materials having thermally activated shape memory characteristics can be used for the catheter tube 60. The catheter tube would remain relatively erectile during the positioning of the electrode assembly 54, but once the RF energy is applied, the thermal energy would cause the Nitinol™ tubing to deflect into an arcuate shape. This means for articulation has the advantage of not requiring the use of pull wires 501 or mechanisms for articulating.
  • It can be seen that the ablation catheter which has been provided above allows for greater choice in the type of lesions which can be made, also allows for greater maneuverability, more precise placement, and better cooling of the electrodes. Although illustrative embodiments of the invention have been shown and described, it is not intended that the novel device be limited thereby. It is to be understood that this novel invention may be susceptible to modifications and variations that are within the scope and fair meaning of the accompanying claims and drawings.

Claims (4)

1. An ablation catheter, which catheter comprises:
a flexible plastic catheter tube; and
at least one linear electrode comprising a tubular array of conductive metal strands carried by said catheter tube, which catheter has a first steering mechanism; and a guiding catheter having a lumen occupied by said ablation catheter, said guiding catheter having a second steering mechanism.
2. The catheter of claim 1 in which said plastic catheter tube extends through said tubular array of conductive metal strands, said catheter tube defining a plurality of apertures to permit the flow of cooling fluid from the lumen of the catheter tube and through said apertures, to flow among said conductive metal strands.
3. The catheter of claim 2 in which a porous second electrode connects with one end of the plastic catheter tube.
4. The catheter of claim 1 in which a porous second electrode connects with one end of the plastic catheter tube.
US11/235,462 2000-08-21 2005-09-26 Ablation catheter with cooled linear electrode Abandoned US20060025763A1 (en)

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US10/657,647 US6986769B2 (en) 2000-08-21 2003-09-08 Ablation catheter with cooled linear electrode
US11/235,462 US20060025763A1 (en) 2000-08-21 2005-09-26 Ablation catheter with cooled linear electrode

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Cited By (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060217705A1 (en) * 2005-02-17 2006-09-28 Baylis Medical Company Inc. Electrosurgical device with discontinuous flow density
US20070027449A1 (en) * 2002-03-05 2007-02-01 Baylis Medical Company Inc. Electrosurgical device and methods
US20070156136A1 (en) * 2002-03-05 2007-07-05 Neil Godara Methods of treating the sacroiliac region of a patient's body
US20070203402A1 (en) * 2002-03-05 2007-08-30 Baylis Medical Elongate member providing a variation in radiopacity
US20070225681A1 (en) * 2006-03-21 2007-09-27 Medtronic Vascular Catheter Having a Selectively Formable Distal Section
US20090024124A1 (en) * 2005-07-14 2009-01-22 Lefler Amy Methods for treating the thoracic region of a patient's body
US20090054962A1 (en) * 2002-03-05 2009-02-26 Baylis Medical Company Inc. Methods for treating the thoracic region of a patient's body
US20100211076A1 (en) * 2008-10-13 2010-08-19 Dfine, Inc. Systems for treating a vertebral body
US20130261615A1 (en) * 2012-03-27 2013-10-03 Dfine, Inc. Methods and systems for use in controlling tissue ablation volume by temperature monitoring
US20140276791A1 (en) * 2013-03-15 2014-09-18 Medtronic Ardian Luxembourg S.A.R.L. Treatment Device With Electrode Contact Surface Configured for Enhancing Uniformity of Electrical Energy Distribution and Associated Devices and Methods
US9113974B2 (en) 2008-09-30 2015-08-25 Dfine, Inc. System for use in treatment of vertebral fractures
US9125671B2 (en) 2010-04-29 2015-09-08 Dfine, Inc. System for use in treatment of vertebral fractures
US9526507B2 (en) 2010-04-29 2016-12-27 Dfine, Inc. System for use in treatment of vertebral fractures
US9610117B2 (en) 2010-04-29 2017-04-04 Dfine, Inc. System for use in treatment of vertebral fractures
US9649116B2 (en) 2010-11-22 2017-05-16 Dfine, Inc. System for use in treatment of vertebral fractures
US9901392B2 (en) 2015-05-11 2018-02-27 Dfine, Inc. System for use in treatment of vertebral fractures
US9918766B2 (en) 2012-12-12 2018-03-20 Dfine, Inc. Devices, methods and systems for affixing an access device to a vertebral body for the insertion of bone cement
US9949789B2 (en) 2002-03-05 2018-04-24 Avent, Inc. Methods of treating the sacroiliac region of a patient's body
US10058336B2 (en) 2010-04-08 2018-08-28 Dfine, Inc. System for use in treatment of vertebral fractures
US10463380B2 (en) 2016-12-09 2019-11-05 Dfine, Inc. Medical devices for treating hard tissues and related methods
US10478241B2 (en) 2016-10-27 2019-11-19 Merit Medical Systems, Inc. Articulating osteotome with cement delivery channel
US10660656B2 (en) 2017-01-06 2020-05-26 Dfine, Inc. Osteotome with a distal portion for simultaneous advancement and articulation
US10786300B2 (en) 2015-04-13 2020-09-29 Carlos Fernando Bazoberry Radiofrequency denervation needle and method
US11026744B2 (en) 2016-11-28 2021-06-08 Dfine, Inc. Tumor ablation devices and related methods
US11052237B2 (en) 2016-11-22 2021-07-06 Dfine, Inc. Swivel hub
US11197681B2 (en) 2009-05-20 2021-12-14 Merit Medical Systems, Inc. Steerable curvable vertebroplasty drill
US11291496B2 (en) 2002-03-05 2022-04-05 Avent, Inc. Methods of treating the sacroiliac region of a patient's body
US11510723B2 (en) 2018-11-08 2022-11-29 Dfine, Inc. Tumor ablation device and related systems and methods

Families Citing this family (239)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6161543A (en) 1993-02-22 2000-12-19 Epicor, Inc. Methods of epicardial ablation for creating a lesion around the pulmonary veins
US6311692B1 (en) 1996-10-22 2001-11-06 Epicor, Inc. Apparatus and method for diagnosis and therapy of electrophysiological disease
US6805128B1 (en) 1996-10-22 2004-10-19 Epicor Medical, Inc. Apparatus and method for ablating tissue
US6719755B2 (en) 1996-10-22 2004-04-13 Epicor Medical, Inc. Methods and devices for ablation
US7052493B2 (en) 1996-10-22 2006-05-30 Epicor Medical, Inc. Methods and devices for ablation
US8709007B2 (en) 1997-10-15 2014-04-29 St. Jude Medical, Atrial Fibrillation Division, Inc. Devices and methods for ablating cardiac tissue
US7892229B2 (en) 2003-01-18 2011-02-22 Tsunami Medtech, Llc Medical instruments and techniques for treating pulmonary disorders
US7674259B2 (en) * 2000-12-09 2010-03-09 Tsunami Medtech Medical instruments and techniques for thermally-mediated therapies
US8016823B2 (en) 2003-01-18 2011-09-13 Tsunami Medtech, Llc Medical instrument and method of use
US8308719B2 (en) 1998-09-21 2012-11-13 St. Jude Medical, Atrial Fibrillation Division, Inc. Apparatus and method for ablating tissue
US20070066972A1 (en) 2001-11-29 2007-03-22 Medwaves, Inc. Ablation catheter apparatus with one or more electrodes
EP1207788A4 (en) 1999-07-19 2009-12-09 St Jude Medical Atrial Fibrill Apparatus and method for ablating tissue
US8048070B2 (en) 2000-03-06 2011-11-01 Salient Surgical Technologies, Inc. Fluid-assisted medical devices, systems and methods
US6689131B2 (en) 2001-03-08 2004-02-10 Tissuelink Medical, Inc. Electrosurgical device having a tissue reduction sensor
US7811282B2 (en) 2000-03-06 2010-10-12 Salient Surgical Technologies, Inc. Fluid-assisted electrosurgical devices, electrosurgical unit with pump and methods of use thereof
ES2643763T3 (en) 2000-03-06 2017-11-24 Salient Surgical Technologies, Inc. Fluid supply system and controller for electrosurgical devices
US6558385B1 (en) 2000-09-22 2003-05-06 Tissuelink Medical, Inc. Fluid-assisted medical device
US7549987B2 (en) * 2000-12-09 2009-06-23 Tsunami Medtech, Llc Thermotherapy device
US9433457B2 (en) * 2000-12-09 2016-09-06 Tsunami Medtech, Llc Medical instruments and techniques for thermally-mediated therapies
JP2005511135A (en) * 2001-11-29 2005-04-28 メッドウェイブズ、インコーポレイテッド High frequency based catheter system with improved deflection and steering mechanisms
US8444636B2 (en) * 2001-12-07 2013-05-21 Tsunami Medtech, Llc Medical instrument and method of use
AU2002357166A1 (en) * 2001-12-12 2003-06-23 Tissuelink Medical, Inc. Fluid-assisted medical devices, systems and methods
ITBS20020039U1 (en) * 2002-03-20 2003-09-22 Fogazzi Di Venturelli Andrea & CATHETER WITH FLEXIBLE COOLED ELECTRODE
EP1572020A4 (en) 2002-10-29 2006-05-03 Tissuelink Medical Inc Fluid-assisted electrosurgical scissors and methods
US10182734B2 (en) 2003-07-18 2019-01-22 Biosense Webster, Inc. Enhanced ablation and mapping catheter and method for treating atrial fibrillation
DE202004021942U1 (en) 2003-09-12 2013-05-13 Vessix Vascular, Inc. Selectable eccentric remodeling and / or ablation of atherosclerotic material
US7727232B1 (en) 2004-02-04 2010-06-01 Salient Surgical Technologies, Inc. Fluid-assisted medical devices and methods
US7282051B2 (en) * 2004-02-04 2007-10-16 Boston Scientific Scimed, Inc. Ablation probe for delivering fluid through porous structure
US7824408B2 (en) 2004-08-05 2010-11-02 Tyco Healthcare Group, Lp Methods and apparatus for coagulating and/or constricting hollow anatomical structures
US9125667B2 (en) 2004-09-10 2015-09-08 Vessix Vascular, Inc. System for inducing desirable temperature effects on body tissue
US8396548B2 (en) 2008-11-14 2013-03-12 Vessix Vascular, Inc. Selective drug delivery in a lumen
US9713730B2 (en) 2004-09-10 2017-07-25 Boston Scientific Scimed, Inc. Apparatus and method for treatment of in-stent restenosis
US20060089637A1 (en) 2004-10-14 2006-04-27 Werneth Randell L Ablation catheter
US8617152B2 (en) 2004-11-15 2013-12-31 Medtronic Ablation Frontiers Llc Ablation system with feedback
KR20070108141A (en) * 2004-11-16 2007-11-08 로버트 엘 베리 Device and method for lung treatment
US7429261B2 (en) 2004-11-24 2008-09-30 Ablation Frontiers, Inc. Atrial ablation catheter and method of use
US7468062B2 (en) 2004-11-24 2008-12-23 Ablation Frontiers, Inc. Atrial ablation catheter adapted for treatment of septal wall arrhythmogenic foci and method of use
US7625372B2 (en) 2005-02-23 2009-12-01 Vnus Medical Technologies, Inc. Methods and apparatus for coagulating and/or constricting hollow anatomical structures
US8182433B2 (en) * 2005-03-04 2012-05-22 Endosense Sa Medical apparatus system having optical fiber load sensing capability
US8075498B2 (en) * 2005-03-04 2011-12-13 Endosense Sa Medical apparatus system having optical fiber load sensing capability
US8932208B2 (en) 2005-05-26 2015-01-13 Maquet Cardiovascular Llc Apparatus and methods for performing minimally-invasive surgical procedures
JP2009500052A (en) 2005-06-20 2009-01-08 アブレーション フロンティアズ，インコーポレーテッド Ablation catheter
AU2006268238A1 (en) 2005-07-11 2007-01-18 Medtronic Ablation Frontiers Llc Low power tissue ablation system
DE202006021213U1 (en) 2005-07-21 2013-11-08 Covidien Lp Apparatus for treating a hollow anatomical structure
US8863746B2 (en) * 2005-07-25 2014-10-21 Kim Technology Partners, LP Device and method for placing within a patient an enteral tube after endotracheal intubation
EP2363073B1 (en) 2005-08-01 2015-10-07 St. Jude Medical Luxembourg Holding S.à.r.l. Medical apparatus system having optical fiber load sensing capability
US20070032785A1 (en) * 2005-08-03 2007-02-08 Jennifer Diederich Tissue evacuation device
US8657814B2 (en) 2005-08-22 2014-02-25 Medtronic Ablation Frontiers Llc User interface for tissue ablation system
US7857809B2 (en) * 2005-12-30 2010-12-28 Biosense Webster, Inc. Injection molded irrigated tip electrode and catheter having the same
US9629567B2 (en) * 2006-01-12 2017-04-25 Biosense Webster, Inc. Mapping of complex fractionated atrial electrogram
US7918850B2 (en) * 2006-02-17 2011-04-05 Biosense Wabster, Inc. Lesion assessment by pacing
JP5173843B2 (en) * 2006-02-22 2013-04-03 カスタム メディカル アプリケーションズ インク． Ablation instruments and related methods
US8019435B2 (en) 2006-05-02 2011-09-13 Boston Scientific Scimed, Inc. Control of arterial smooth muscle tone
US8567265B2 (en) 2006-06-09 2013-10-29 Endosense, SA Triaxial fiber optic force sensing catheter
US8048063B2 (en) 2006-06-09 2011-11-01 Endosense Sa Catheter having tri-axial force sensor
US8068920B2 (en) * 2006-10-03 2011-11-29 Vincent A Gaudiani Transcoronary sinus pacing system, LV summit pacing, early mitral closure pacing, and methods therefor
AU2007310986B2 (en) 2006-10-18 2013-07-04 Boston Scientific Scimed, Inc. Inducing desirable temperature effects on body tissue
AU2007310988B2 (en) 2006-10-18 2013-08-15 Vessix Vascular, Inc. Tuned RF energy and electrical tissue characterization for selective treatment of target tissues
US7993323B2 (en) 2006-11-13 2011-08-09 Uptake Medical Corp. High pressure and high temperature vapor catheters and systems
US7907994B2 (en) 2007-01-11 2011-03-15 Biosense Webster, Inc. Automated pace-mapping for identification of cardiac arrhythmic conductive pathways and foci
WO2008118737A1 (en) 2007-03-22 2008-10-02 University Of Virginia Patent Foundation Electrode catheter for ablation purposes and related method thereof
US10166066B2 (en) 2007-03-13 2019-01-01 University Of Virginia Patent Foundation Epicardial ablation catheter and method of use
WO2008115745A2 (en) 2007-03-19 2008-09-25 University Of Virginia Patent Foundation Access needle pressure sensor device and method of use
US11058354B2 (en) 2007-03-19 2021-07-13 University Of Virginia Patent Foundation Access needle with direct visualization and related methods
US9468396B2 (en) 2007-03-19 2016-10-18 University Of Virginia Patent Foundation Systems and methods for determining location of an access needle in a subject
US9314298B2 (en) * 2007-04-17 2016-04-19 St. Jude Medical, Atrial Fibrillation Divisions, Inc. Vacuum-stabilized ablation system
US8597288B2 (en) * 2008-10-01 2013-12-03 St. Jude Medical, Artial Fibrillation Division, Inc. Vacuum-stabilized ablation system
US8641704B2 (en) 2007-05-11 2014-02-04 Medtronic Ablation Frontiers Llc Ablation therapy system and method for treating continuous atrial fibrillation
US8734440B2 (en) * 2007-07-03 2014-05-27 St. Jude Medical, Atrial Fibrillation Division, Inc. Magnetically guided catheter
US8206404B2 (en) 2007-07-03 2012-06-26 St. Jude Medical, Atrial Fibrillation Division, Inc. Magnetically guided catheter
US8157789B2 (en) * 2007-05-24 2012-04-17 Endosense Sa Touch sensing catheter
US8622935B1 (en) 2007-05-25 2014-01-07 Endosense Sa Elongated surgical manipulator with body position and distal force sensing
EP2170198B1 (en) 2007-07-06 2015-04-15 Tsunami Medtech, LLC Medical system
EP2198797B1 (en) 2007-08-23 2011-04-13 Aegea Medical, Inc. Uterine therapy device
EP2209517A4 (en) 2007-10-05 2011-03-30 Maquet Cardiovascular Llc Devices and methods for minimally-invasive surgical procedures
US8322335B2 (en) * 2007-10-22 2012-12-04 Uptake Medical Corp. Determining patient-specific vapor treatment and delivery parameters
BRPI0818239A2 (en) * 2007-10-22 2017-12-05 Uptake Medical Corp determination of patient-specific treatment parameters and steam delivery
US8359092B2 (en) * 2007-11-29 2013-01-22 Biosense Webster, Inc. Determining locations of ganglia and plexi in the heart using complex fractionated atrial electrogram
US8118809B2 (en) * 2007-12-21 2012-02-21 St. Jude Medical, Atrial Fibrillation Division, Inc. Flexible conductive polymer electrode and method for ablation
US9924992B2 (en) 2008-02-20 2018-03-27 Tsunami Medtech, Llc Medical system and method of use
US8298227B2 (en) * 2008-05-14 2012-10-30 Endosense Sa Temperature compensated strain sensing catheter
US8721632B2 (en) 2008-09-09 2014-05-13 Tsunami Medtech, Llc Methods for delivering energy into a target tissue of a body
US8357149B2 (en) 2008-06-05 2013-01-22 Biosense Webster, Inc. Filter for simultaneous pacing and ablation
US8579888B2 (en) 2008-06-17 2013-11-12 Tsunami Medtech, Llc Medical probes for the treatment of blood vessels
US7904143B2 (en) * 2008-07-07 2011-03-08 Biosense Webster, Inc. Binary logistic mixed model for complex fractionated atrial electrogram procedures
CN102238920B (en) * 2008-10-06 2015-03-25 维兰德.K.沙马 Method and apparatus for tissue ablation
US9561066B2 (en) 2008-10-06 2017-02-07 Virender K. Sharma Method and apparatus for tissue ablation
US10064697B2 (en) 2008-10-06 2018-09-04 Santa Anna Tech Llc Vapor based ablation system for treating various indications
US9561068B2 (en) 2008-10-06 2017-02-07 Virender K. Sharma Method and apparatus for tissue ablation
US10695126B2 (en) 2008-10-06 2020-06-30 Santa Anna Tech Llc Catheter with a double balloon structure to generate and apply a heated ablative zone to tissue
AU2009314133B2 (en) 2008-11-17 2015-12-10 Vessix Vascular, Inc. Selective accumulation of energy with or without knowledge of tissue topography
US8475450B2 (en) 2008-12-30 2013-07-02 Biosense Webster, Inc. Dual-purpose lasso catheter with irrigation
US8600472B2 (en) 2008-12-30 2013-12-03 Biosense Webster (Israel), Ltd. Dual-purpose lasso catheter with irrigation using circumferentially arranged ring bump electrodes
US11284931B2 (en) * 2009-02-03 2022-03-29 Tsunami Medtech, Llc Medical systems and methods for ablating and absorbing tissue
US8728068B2 (en) * 2009-04-09 2014-05-20 Urologix, Inc. Cooled antenna for device insertable into a body
US8954161B2 (en) 2012-06-01 2015-02-10 Advanced Cardiac Therapeutics, Inc. Systems and methods for radiometrically measuring temperature and detecting tissue contact prior to and during tissue ablation
US8926605B2 (en) 2012-02-07 2015-01-06 Advanced Cardiac Therapeutics, Inc. Systems and methods for radiometrically measuring temperature during tissue ablation
US9226791B2 (en) 2012-03-12 2016-01-05 Advanced Cardiac Therapeutics, Inc. Systems for temperature-controlled ablation using radiometric feedback
US9277961B2 (en) 2009-06-12 2016-03-08 Advanced Cardiac Therapeutics, Inc. Systems and methods of radiometrically determining a hot-spot temperature of tissue being treated
US9642534B2 (en) 2009-09-11 2017-05-09 University Of Virginia Patent Foundation Systems and methods for determining location of an access needle in a subject
US8900223B2 (en) * 2009-11-06 2014-12-02 Tsunami Medtech, Llc Tissue ablation systems and methods of use
CN102711648B (en) * 2009-11-30 2015-07-29 麦迪威公司 There is the radio frequency ablation system of tracking transducer
US8920415B2 (en) * 2009-12-16 2014-12-30 Biosense Webster (Israel) Ltd. Catheter with helical electrode
US9161801B2 (en) * 2009-12-30 2015-10-20 Tsunami Medtech, Llc Medical system and method of use
US8608735B2 (en) * 2009-12-30 2013-12-17 Biosense Webster (Israel) Ltd. Catheter with arcuate end section
US9616246B2 (en) 2010-01-04 2017-04-11 Covidien Lp Apparatus and methods for treating hollow anatomical structures
US9113927B2 (en) * 2010-01-29 2015-08-25 Covidien Lp Apparatus and methods of use for treating blood vessels
EP2537149B1 (en) 2010-02-18 2017-10-25 University Of Virginia Patent Foundation System, method, and computer program product for simulating epicardial electrophysiology procedures
KR20130108067A (en) 2010-04-09 2013-10-02 베식스 바스큘라 인코포레이티드 Power generating and control apparatus for the treatment of tissue
US9192790B2 (en) 2010-04-14 2015-11-24 Boston Scientific Scimed, Inc. Focused ultrasonic renal denervation
US8473067B2 (en) 2010-06-11 2013-06-25 Boston Scientific Scimed, Inc. Renal denervation and stimulation employing wireless vascular energy transfer arrangement
US9155589B2 (en) 2010-07-30 2015-10-13 Boston Scientific Scimed, Inc. Sequential activation RF electrode set for renal nerve ablation
US9358365B2 (en) 2010-07-30 2016-06-07 Boston Scientific Scimed, Inc. Precision electrode movement control for renal nerve ablation
US9463062B2 (en) 2010-07-30 2016-10-11 Boston Scientific Scimed, Inc. Cooled conductive balloon RF catheter for renal nerve ablation
US9408661B2 (en) 2010-07-30 2016-08-09 Patrick A. Haverkost RF electrodes on multiple flexible wires for renal nerve ablation
US9084609B2 (en) 2010-07-30 2015-07-21 Boston Scientific Scime, Inc. Spiral balloon catheter for renal nerve ablation
US8945118B2 (en) 2010-08-04 2015-02-03 St. Jude Medical, Atrial Fibrillation Division, Inc. Catheter with flexible tether and introducer for a catheter
US9023033B2 (en) 2010-08-04 2015-05-05 St. Jude Medical, Atrial Fibrillation Division, Inc. Magnetically guided catheters
US8715280B2 (en) 2010-08-04 2014-05-06 St. Jude Medical, Atrial Fibrillation Division, Inc. Magnetically guided catheters
EP2603276A4 (en) 2010-08-13 2017-07-05 Cathrx Ltd A catheter sheath and a method of manufacturing
US9943353B2 (en) 2013-03-15 2018-04-17 Tsunami Medtech, Llc Medical system and method of use
CN103096828B (en) * 2010-08-13 2016-07-13 导管治疗有限公司 Irrigating catheter
US9084610B2 (en) 2010-10-21 2015-07-21 Medtronic Ardian Luxembourg S.A.R.L. Catheter apparatuses, systems, and methods for renal neuromodulation
US8974451B2 (en) 2010-10-25 2015-03-10 Boston Scientific Scimed, Inc. Renal nerve ablation using conductive fluid jet and RF energy
US9220558B2 (en) 2010-10-27 2015-12-29 Boston Scientific Scimed, Inc. RF renal denervation catheter with multiple independent electrodes
WO2012064864A1 (en) 2010-11-09 2012-05-18 Aegea Medical Inc. Positioning method and apparatus for delivering vapor to the uterus
US9028485B2 (en) 2010-11-15 2015-05-12 Boston Scientific Scimed, Inc. Self-expanding cooling electrode for renal nerve ablation
US9089350B2 (en) 2010-11-16 2015-07-28 Boston Scientific Scimed, Inc. Renal denervation catheter with RF electrode and integral contrast dye injection arrangement
US9668811B2 (en) 2010-11-16 2017-06-06 Boston Scientific Scimed, Inc. Minimally invasive access for renal nerve ablation
US9326751B2 (en) 2010-11-17 2016-05-03 Boston Scientific Scimed, Inc. Catheter guidance of external energy for renal denervation
US9060761B2 (en) 2010-11-18 2015-06-23 Boston Scientific Scime, Inc. Catheter-focused magnetic field induced renal nerve ablation
US9192435B2 (en) 2010-11-22 2015-11-24 Boston Scientific Scimed, Inc. Renal denervation catheter with cooled RF electrode
US9023034B2 (en) 2010-11-22 2015-05-05 Boston Scientific Scimed, Inc. Renal ablation electrode with force-activatable conduction apparatus
US20120157993A1 (en) 2010-12-15 2012-06-21 Jenson Mark L Bipolar Off-Wall Electrode Device for Renal Nerve Ablation
WO2012100095A1 (en) 2011-01-19 2012-07-26 Boston Scientific Scimed, Inc. Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury
US9220433B2 (en) * 2011-06-30 2015-12-29 Biosense Webster (Israel), Ltd. Catheter with variable arcuate distal section
CN103813745B (en) 2011-07-20 2016-06-29 波士顿科学西美德公司 In order to visualize, be directed at and to melt transcutaneous device and the method for nerve
JP6106669B2 (en) 2011-07-22 2017-04-05 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． A neuromodulation system having a neuromodulation element that can be placed in a helical guide
US9662169B2 (en) 2011-07-30 2017-05-30 Biosense Webster (Israel) Ltd. Catheter with flow balancing valve
EP2792323B1 (en) 2011-08-25 2017-10-04 Covidien LP Systems and devices for treatment of luminal tissue
CA2851355C (en) 2011-10-07 2020-02-18 Aegea Medical Inc. Integrity testing method and apparatus for delivering vapor to the uterus
WO2013055826A1 (en) 2011-10-10 2013-04-18 Boston Scientific Scimed, Inc. Medical devices including ablation electrodes
US10085799B2 (en) 2011-10-11 2018-10-02 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US9420955B2 (en) 2011-10-11 2016-08-23 Boston Scientific Scimed, Inc. Intravascular temperature monitoring system and method
US9364284B2 (en) 2011-10-12 2016-06-14 Boston Scientific Scimed, Inc. Method of making an off-wall spacer cage
EP2768568B1 (en) 2011-10-18 2020-05-06 Boston Scientific Scimed, Inc. Integrated crossing balloon catheter
WO2013058962A1 (en) 2011-10-18 2013-04-25 Boston Scientific Scimed, Inc. Deflectable medical devices
EP2775948B1 (en) 2011-11-08 2018-04-04 Boston Scientific Scimed, Inc. Ostial renal nerve ablation
US9119600B2 (en) 2011-11-15 2015-09-01 Boston Scientific Scimed, Inc. Device and methods for renal nerve modulation monitoring
US9119632B2 (en) 2011-11-21 2015-09-01 Boston Scientific Scimed, Inc. Deflectable renal nerve ablation catheter
US9265969B2 (en) 2011-12-21 2016-02-23 Cardiac Pacemakers, Inc. Methods for modulating cell function
WO2013096916A2 (en) 2011-12-23 2013-06-27 Vessix Vascular, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
US9433760B2 (en) 2011-12-28 2016-09-06 Boston Scientific Scimed, Inc. Device and methods for nerve modulation using a novel ablation catheter with polymeric ablative elements
CN104023663B (en) * 2011-12-29 2018-12-21 圣犹达医疗用品电生理部门有限公司 System for optimizing the damage that coupling ablation catheter to bodily tissue and assessment is formed by conduit
US9050106B2 (en) 2011-12-29 2015-06-09 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US10660703B2 (en) 2012-05-08 2020-05-26 Boston Scientific Scimed, Inc. Renal nerve modulation devices
US9717555B2 (en) * 2012-05-14 2017-08-01 Biosense Webster (Israel), Ltd. Catheter with helical end section for vessel ablation
US10321946B2 (en) 2012-08-24 2019-06-18 Boston Scientific Scimed, Inc. Renal nerve modulation devices with weeping RF ablation balloons
US9173696B2 (en) 2012-09-17 2015-11-03 Boston Scientific Scimed, Inc. Self-positioning electrode system and method for renal nerve modulation
US10549127B2 (en) 2012-09-21 2020-02-04 Boston Scientific Scimed, Inc. Self-cooling ultrasound ablation catheter
US10398464B2 (en) 2012-09-21 2019-09-03 Boston Scientific Scimed, Inc. System for nerve modulation and innocuous thermal gradient nerve block
CN104869930B (en) 2012-10-10 2020-12-25 波士顿科学国际有限公司 Renal neuromodulation apparatus and methods
US9044575B2 (en) 2012-10-22 2015-06-02 Medtronic Adrian Luxembourg S.a.r.l. Catheters with enhanced flexibility and associated devices, systems, and methods
CN103892906B (en) * 2012-12-27 2016-12-28 四川锦江电子科技有限公司 Wound-rotor type perfusion conduit
EP2945556A4 (en) 2013-01-17 2016-08-31 Virender K Sharma Method and apparatus for tissue ablation
US9956033B2 (en) 2013-03-11 2018-05-01 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9693821B2 (en) 2013-03-11 2017-07-04 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9808311B2 (en) 2013-03-13 2017-11-07 Boston Scientific Scimed, Inc. Deflectable medical devices
US10265122B2 (en) 2013-03-15 2019-04-23 Boston Scientific Scimed, Inc. Nerve ablation devices and related methods of use
EP2967734B1 (en) 2013-03-15 2019-05-15 Boston Scientific Scimed, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
US9297845B2 (en) 2013-03-15 2016-03-29 Boston Scientific Scimed, Inc. Medical devices and methods for treatment of hypertension that utilize impedance compensation
JP2014213173A (en) * 2013-04-30 2014-11-17 日本ライフライン株式会社 Electrode catheter
US10548663B2 (en) 2013-05-18 2020-02-04 Medtronic Ardian Luxembourg S.A.R.L. Neuromodulation catheters with shafts for enhanced flexibility and control and associated devices, systems, and methods
CN105473092B (en) 2013-06-21 2019-05-17 波士顿科学国际有限公司 The medical instrument for renal nerve ablation with rotatable shaft
EP3010437A1 (en) 2013-06-21 2016-04-27 Boston Scientific Scimed, Inc. Renal denervation balloon catheter with ride along electrode support
US9707036B2 (en) 2013-06-25 2017-07-18 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation using localized indifferent electrodes
WO2015002787A1 (en) 2013-07-01 2015-01-08 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
EP3019106A1 (en) 2013-07-11 2016-05-18 Boston Scientific Scimed, Inc. Medical device with stretchable electrode assemblies
WO2015006480A1 (en) 2013-07-11 2015-01-15 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation
WO2015010074A1 (en) 2013-07-19 2015-01-22 Boston Scientific Scimed, Inc. Spiral bipolar electrode renal denervation balloon
WO2015013205A1 (en) 2013-07-22 2015-01-29 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
US10695124B2 (en) 2013-07-22 2020-06-30 Boston Scientific Scimed, Inc. Renal nerve ablation catheter having twist balloon
WO2015027096A1 (en) 2013-08-22 2015-02-26 Boston Scientific Scimed, Inc. Flexible circuit having improved adhesion to a renal nerve modulation balloon
EP3041425B1 (en) 2013-09-04 2022-04-13 Boston Scientific Scimed, Inc. Radio frequency (rf) balloon catheter having flushing and cooling capability
WO2015038947A1 (en) 2013-09-13 2015-03-19 Boston Scientific Scimed, Inc. Ablation balloon with vapor deposited cover layer
US9782211B2 (en) 2013-10-01 2017-10-10 Uptake Medical Technology Inc. Preferential volume reduction of diseased segments of a heterogeneous lobe
US11246654B2 (en) 2013-10-14 2022-02-15 Boston Scientific Scimed, Inc. Flexible renal nerve ablation devices and related methods of use and manufacture
CN105592778B (en) 2013-10-14 2019-07-23 波士顿科学医学有限公司 High-resolution cardiac mapping electrod-array conduit
US9770606B2 (en) 2013-10-15 2017-09-26 Boston Scientific Scimed, Inc. Ultrasound ablation catheter with cooling infusion and centering basket
AU2014334574B2 (en) 2013-10-15 2017-07-06 Boston Scientific Scimed, Inc. Medical device balloon
CN105636538B (en) 2013-10-18 2019-01-15 波士顿科学国际有限公司 Foley's tube with flexible wire and its correlation technique for using and manufacturing
CN105658163B (en) 2013-10-25 2020-08-18 波士顿科学国际有限公司 Embedded thermocouple in denervation flexible circuit
WO2015103617A1 (en) 2014-01-06 2015-07-09 Boston Scientific Scimed, Inc. Tear resistant flex circuit assembly
EP4253024A3 (en) 2014-01-27 2023-12-27 Medtronic Ireland Manufacturing Unlimited Company Neuromodulation catheters having jacketed neuromodulation elements and related devices
US9554718B2 (en) 2014-01-29 2017-01-31 Biosense Webster (Israel) Ltd. Double bipolar configuration for atrial fibrillation annotation
US9380953B2 (en) 2014-01-29 2016-07-05 Biosense Webster (Israel) Ltd. Hybrid bipolar/unipolar detection of activation wavefront
DE102014201859A1 (en) * 2014-02-03 2015-08-06 Olympus Winter & Ibe Gmbh Electrosurgical instrument
US11000679B2 (en) 2014-02-04 2021-05-11 Boston Scientific Scimed, Inc. Balloon protection and rewrapping devices and related methods of use
JP6325121B2 (en) 2014-02-04 2018-05-16 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． Alternative placement of temperature sensors on bipolar electrodes
US10736690B2 (en) 2014-04-24 2020-08-11 Medtronic Ardian Luxembourg S.A.R.L. Neuromodulation catheters and associated systems and methods
WO2015179666A1 (en) 2014-05-22 2015-11-26 Aegea Medical Inc. Systems and methods for performing endometrial ablation
ES2942296T3 (en) 2014-05-22 2023-05-31 Aegea Medical Inc Integrity test method and apparatus for administering vapor to the uterus
AU2015318795A1 (en) * 2014-09-15 2017-03-02 Cathrx Ltd An irrigated ablation catheter and process thereof
EP3220843B1 (en) 2014-11-19 2020-01-01 EPiX Therapeutics, Inc. Ablation devices and methods of using a high-resolution electrode assembly
JP6673598B2 (en) 2014-11-19 2020-03-25 エピックス セラピューティクス，インコーポレイテッド High resolution mapping of tissue with pacing
CA2967829A1 (en) 2014-11-19 2016-05-26 Advanced Cardiac Therapeutics, Inc. Systems and methods for high-resolution mapping of tissue
US10485604B2 (en) 2014-12-02 2019-11-26 Uptake Medical Technology Inc. Vapor treatment of lung nodules and tumors
US9421061B2 (en) 2014-12-18 2016-08-23 Biosense Webster (Israel) Ltd. Ventricular far field reduction
US10034707B2 (en) 2014-12-30 2018-07-31 Biosense Webster (Israel) Ltd. Catheter with irrigated tip electrode with porous substrate and high density surface micro-electrodes
US10531906B2 (en) 2015-02-02 2020-01-14 Uptake Medical Technology Inc. Medical vapor generator
US9833161B2 (en) 2015-02-09 2017-12-05 Biosense Webster (Israel) Ltd. Basket catheter with far-field electrode
US9636164B2 (en) 2015-03-25 2017-05-02 Advanced Cardiac Therapeutics, Inc. Contact sensing systems and methods
US9775673B2 (en) * 2015-03-26 2017-10-03 Garner B. Meads, JR. Nasal coagulation suction device and methods
US10806512B2 (en) 2015-03-26 2020-10-20 Garner B. Meads, JR. Nasal coagulation suction device and methods
EP3209236B1 (en) 2015-03-31 2020-06-10 St. Jude Medical, Cardiology Division, Inc. Device for delivering pulsed rf energy during catheter ablation
JP2017121313A (en) * 2016-01-06 2017-07-13 日本ライフライン株式会社 Catheter and catheter device
CN108430368B (en) 2016-01-07 2022-05-31 圣犹达医疗用品国际控股有限公司 Medical device with multi-core optical fiber for optical sensing
US11331037B2 (en) 2016-02-19 2022-05-17 Aegea Medical Inc. Methods and apparatus for determining the integrity of a bodily cavity
SG11201807618QA (en) 2016-03-15 2018-10-30 Epix Therapeutics Inc Improved devices, systems and methods for irrigated ablation
US11331140B2 (en) 2016-05-19 2022-05-17 Aqua Heart, Inc. Heated vapor ablation systems and methods for treating cardiac conditions
JP6718557B2 (en) 2016-10-04 2020-07-08 セント・ジュード・メディカル，カーディオロジー・ディヴィジョン，インコーポレイテッド Ablation catheter tip
KR20190062419A (en) 2016-10-04 2019-06-05 아벤트, 인크. The cooled RF probe
WO2018200865A1 (en) 2017-04-27 2018-11-01 Epix Therapeutics, Inc. Determining nature of contact between catheter tip and tissue
US11129673B2 (en) 2017-05-05 2021-09-28 Uptake Medical Technology Inc. Extra-airway vapor ablation for treating airway constriction in patients with asthma and COPD
US11344364B2 (en) 2017-09-07 2022-05-31 Uptake Medical Technology Inc. Screening method for a target nerve to ablate for the treatment of inflammatory lung disease
US11350988B2 (en) 2017-09-11 2022-06-07 Uptake Medical Technology Inc. Bronchoscopic multimodality lung tumor treatment
USD845467S1 (en) 2017-09-17 2019-04-09 Uptake Medical Technology Inc. Hand-piece for medical ablation catheter
US11419658B2 (en) 2017-11-06 2022-08-23 Uptake Medical Technology Inc. Method for treating emphysema with condensable thermal vapor
US11490946B2 (en) 2017-12-13 2022-11-08 Uptake Medical Technology Inc. Vapor ablation handpiece
CA3102080A1 (en) 2018-06-01 2019-12-05 Santa Anna Tech Llc Multi-stage vapor-based ablation treatment methods and vapor generation and delivery systems
US11577075B1 (en) 2018-10-12 2023-02-14 Vincent A. Gaudiani Transcoronary sinus pacing of his bundle
US11648397B1 (en) 2018-10-12 2023-05-16 Vincent Gaudiani Transcoronary sinus pacing of posteroseptal left ventricular base
US11653927B2 (en) 2019-02-18 2023-05-23 Uptake Medical Technology Inc. Vapor ablation treatment of obstructive lung disease
EP4167892A1 (en) 2020-06-19 2023-04-26 Remedy Robotics, Inc. Systems and methods for guidance of intraluminal devices within the vasculature
US11707332B2 (en) 2021-07-01 2023-07-25 Remedy Robotics, Inc. Image space control for endovascular tools
AU2022305235A1 (en) 2021-07-01 2024-01-18 Remedy Robotics, Inc. Vision-based position and orientation determination for endovascular tools
EP4349288A1 (en) 2022-10-07 2024-04-10 Erbe Elektromedizin GmbH Ablation probe with internal cooling
EP4349289A1 (en) 2022-10-07 2024-04-10 Erbe Elektromedizin GmbH Probe with distal cutting electrode
EP4349287A1 (en) 2022-10-07 2024-04-10 Erbe Elektromedizin GmbH Ablation instrument

Citations (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5531685A (en) * 1993-06-11 1996-07-02 Catheter Research, Inc. Steerable variable stiffness device
US5733316A (en) * 1995-10-27 1998-03-31 Dornier Medical Systems, Inc. Organ separation for thermal therapy
US5800482A (en) * 1996-03-06 1998-09-01 Cardiac Pathways Corporation Apparatus and method for linear lesion ablation
US5913856A (en) * 1997-05-19 1999-06-22 Irvine Biomedical, Inc. Catheter system having a porous shaft and fluid irrigation capabilities
US5913854A (en) * 1997-02-04 1999-06-22 Medtronic, Inc. Fluid cooled ablation catheter and method for making
US5916213A (en) * 1997-02-04 1999-06-29 Medtronic, Inc. Systems and methods for tissue mapping and ablation
US5919188A (en) * 1997-02-04 1999-07-06 Medtronic, Inc. Linear ablation catheter
US5938694A (en) * 1993-11-10 1999-08-17 Medtronic Cardiorhythm Electrode array catheter
US6015407A (en) * 1996-03-06 2000-01-18 Cardiac Pathways Corporation Combination linear ablation and cooled tip RF catheters
US6083222A (en) * 1995-02-28 2000-07-04 Boston Scientific Corporation Deflectable catheter for ablating cardiac tissue
US6113556A (en) * 1992-02-14 2000-09-05 Avitall; Boaz Biplanar deflectable catheter for arrhythmogenic tissue ablation
US6212434B1 (en) * 1998-07-22 2001-04-03 Cardiac Pacemakers, Inc. Single pass lead system
US6224587B1 (en) * 1999-11-22 2001-05-01 C.R. Bard, Inc. Steerable catheter
US6425894B1 (en) * 2000-07-12 2002-07-30 Biosense Webster, Inc. Ablation catheter with electrode temperature monitoring
US6475217B1 (en) * 1999-10-05 2002-11-05 Sherwood Services Ag Articulating ionizable gas coagulator
US6522930B1 (en) * 1998-05-06 2003-02-18 Atrionix, Inc. Irrigated ablation device assembly
US6607505B1 (en) * 1996-12-19 2003-08-19 Ep Technologies, Inc. Catheter distal assembly with pull wires

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4896671A (en) * 1988-08-01 1990-01-30 C. R. Bard, Inc. Catheter with contoured ablation electrode
WO1994002077A2 (en) 1992-07-15 1994-02-03 Angelase, Inc. Ablation catheter system
US5487385A (en) * 1993-12-03 1996-01-30 Avitall; Boaz Atrial mapping and ablation catheter system
US5462521A (en) * 1993-12-21 1995-10-31 Angeion Corporation Fluid cooled and perfused tip for a catheter
US5797905A (en) * 1994-08-08 1998-08-25 E. P. Technologies Inc. Flexible tissue ablation elements for making long lesions
US6090104A (en) * 1995-06-07 2000-07-18 Cordis Webster, Inc. Catheter with a spirally wound flat ribbon electrode
US6032077A (en) * 1996-03-06 2000-02-29 Cardiac Pathways Corporation Ablation catheter with electrical coupling via foam drenched with a conductive fluid
US5755760A (en) * 1996-03-11 1998-05-26 Medtronic, Inc. Deflectable catheter
US6171277B1 (en) * 1997-12-01 2001-01-09 Cordis Webster, Inc. Bi-directional control handle for steerable catheter
US6120476A (en) 1997-12-01 2000-09-19 Cordis Webster, Inc. Irrigated tip catheter

Patent Citations (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6113556A (en) * 1992-02-14 2000-09-05 Avitall; Boaz Biplanar deflectable catheter for arrhythmogenic tissue ablation
US5531685A (en) * 1993-06-11 1996-07-02 Catheter Research, Inc. Steerable variable stiffness device
US5938694A (en) * 1993-11-10 1999-08-17 Medtronic Cardiorhythm Electrode array catheter
US6083222A (en) * 1995-02-28 2000-07-04 Boston Scientific Corporation Deflectable catheter for ablating cardiac tissue
US5733316A (en) * 1995-10-27 1998-03-31 Dornier Medical Systems, Inc. Organ separation for thermal therapy
US6015407A (en) * 1996-03-06 2000-01-18 Cardiac Pathways Corporation Combination linear ablation and cooled tip RF catheters
US5800482A (en) * 1996-03-06 1998-09-01 Cardiac Pathways Corporation Apparatus and method for linear lesion ablation
US6607505B1 (en) * 1996-12-19 2003-08-19 Ep Technologies, Inc. Catheter distal assembly with pull wires
US5913854A (en) * 1997-02-04 1999-06-22 Medtronic, Inc. Fluid cooled ablation catheter and method for making
US5919188A (en) * 1997-02-04 1999-07-06 Medtronic, Inc. Linear ablation catheter
US5916213A (en) * 1997-02-04 1999-06-29 Medtronic, Inc. Systems and methods for tissue mapping and ablation
US5913856A (en) * 1997-05-19 1999-06-22 Irvine Biomedical, Inc. Catheter system having a porous shaft and fluid irrigation capabilities
US6522930B1 (en) * 1998-05-06 2003-02-18 Atrionix, Inc. Irrigated ablation device assembly
US6212434B1 (en) * 1998-07-22 2001-04-03 Cardiac Pacemakers, Inc. Single pass lead system
US6475217B1 (en) * 1999-10-05 2002-11-05 Sherwood Services Ag Articulating ionizable gas coagulator
US6224587B1 (en) * 1999-11-22 2001-05-01 C.R. Bard, Inc. Steerable catheter
US6425894B1 (en) * 2000-07-12 2002-07-30 Biosense Webster, Inc. Ablation catheter with electrode temperature monitoring

Cited By (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10206739B2 (en) 2002-03-05 2019-02-19 Avent, Inc. Electrosurgical device and methods
US20070027449A1 (en) * 2002-03-05 2007-02-01 Baylis Medical Company Inc. Electrosurgical device and methods
US20070156136A1 (en) * 2002-03-05 2007-07-05 Neil Godara Methods of treating the sacroiliac region of a patient's body
US20070203402A1 (en) * 2002-03-05 2007-08-30 Baylis Medical Elongate member providing a variation in radiopacity
US9216053B2 (en) 2002-03-05 2015-12-22 Avent, Inc. Elongate member providing a variation in radiopacity
US20090054962A1 (en) * 2002-03-05 2009-02-26 Baylis Medical Company Inc. Methods for treating the thoracic region of a patient's body
US9949789B2 (en) 2002-03-05 2018-04-24 Avent, Inc. Methods of treating the sacroiliac region of a patient's body
US11291496B2 (en) 2002-03-05 2022-04-05 Avent, Inc. Methods of treating the sacroiliac region of a patient's body
US9820808B2 (en) 2002-03-05 2017-11-21 Avent, Inc. Method for treating the thoracic region of a patient's body
US9364281B2 (en) 2002-03-05 2016-06-14 Avent, Inc. Methods for treating the thoracic region of a patient's body
US8864759B2 (en) 2004-11-15 2014-10-21 Kimberly-Clark Inc. Methods of treating the sacroiliac region of a patient's body
US20110040362A1 (en) * 2004-11-15 2011-02-17 Neil Godara Methods of Treating the Sacroiliac Region of a Patient's Body
US20060217705A1 (en) * 2005-02-17 2006-09-28 Baylis Medical Company Inc. Electrosurgical device with discontinuous flow density
US8951249B2 (en) 2005-02-17 2015-02-10 Avent Inc. Electrosurgical device with discontinuous flow density
US20090024124A1 (en) * 2005-07-14 2009-01-22 Lefler Amy Methods for treating the thoracic region of a patient's body
US20070225681A1 (en) * 2006-03-21 2007-09-27 Medtronic Vascular Catheter Having a Selectively Formable Distal Section
US9113974B2 (en) 2008-09-30 2015-08-25 Dfine, Inc. System for use in treatment of vertebral fractures
US9913675B2 (en) 2008-09-30 2018-03-13 Dfine, Inc. System for use in treatment of vertebral fractures
US10245092B2 (en) 2008-09-30 2019-04-02 Dfine, Inc. System for use in treatment of vertebral fractures
US10299805B2 (en) 2008-09-30 2019-05-28 Dfine, Inc. Systems for treating a vertebral body
US9421057B2 (en) 2008-09-30 2016-08-23 Dfine, Inc. System for use in treatment of vertebral fractures
US8758349B2 (en) 2008-10-13 2014-06-24 Dfine, Inc. Systems for treating a vertebral body
US9504481B2 (en) 2008-10-13 2016-11-29 Dfine, Inc. Systems for treating a vertebral body
US9161809B2 (en) 2008-10-13 2015-10-20 Dfine, Inc. Systems for treating a vertebral body
US20100211076A1 (en) * 2008-10-13 2010-08-19 Dfine, Inc. Systems for treating a vertebral body
US11197681B2 (en) 2009-05-20 2021-12-14 Merit Medical Systems, Inc. Steerable curvable vertebroplasty drill
US10058336B2 (en) 2010-04-08 2018-08-28 Dfine, Inc. System for use in treatment of vertebral fractures
US9610117B2 (en) 2010-04-29 2017-04-04 Dfine, Inc. System for use in treatment of vertebral fractures
US10327841B2 (en) 2010-04-29 2019-06-25 Dfine, Inc. System for use in treatment of vertebral fractures
US9125671B2 (en) 2010-04-29 2015-09-08 Dfine, Inc. System for use in treatment of vertebral fractures
US10624652B2 (en) 2010-04-29 2020-04-21 Dfine, Inc. System for use in treatment of vertebral fractures
US9743938B2 (en) 2010-04-29 2017-08-29 Dfine, Inc. System for use in treatment of vertebral fractures
US9526507B2 (en) 2010-04-29 2016-12-27 Dfine, Inc. System for use in treatment of vertebral fractures
US10123809B2 (en) 2010-04-29 2018-11-13 Merit Medical Systems, Inc. System for use in treatment of vertebral fractures
US9649116B2 (en) 2010-11-22 2017-05-16 Dfine, Inc. System for use in treatment of vertebral fractures
US8864760B2 (en) * 2012-03-27 2014-10-21 Dfine, Inc. Methods and systems for use in controlling tissue ablation volume by temperature monitoring
US20140350542A1 (en) * 2012-03-27 2014-11-27 Dfine, Inc. Methods and systems for use in controlling tissue ablation volume by temperature monitoring
US20130261615A1 (en) * 2012-03-27 2013-10-03 Dfine, Inc. Methods and systems for use in controlling tissue ablation volume by temperature monitoring
US10028784B2 (en) * 2012-03-27 2018-07-24 Dfine, Inc. Methods and systems for use in controlling tissue ablation volume by temperature monitoring
US9918766B2 (en) 2012-12-12 2018-03-20 Dfine, Inc. Devices, methods and systems for affixing an access device to a vertebral body for the insertion of bone cement
US20140276791A1 (en) * 2013-03-15 2014-09-18 Medtronic Ardian Luxembourg S.A.R.L. Treatment Device With Electrode Contact Surface Configured for Enhancing Uniformity of Electrical Energy Distribution and Associated Devices and Methods
US10786300B2 (en) 2015-04-13 2020-09-29 Carlos Fernando Bazoberry Radiofrequency denervation needle and method
US9901392B2 (en) 2015-05-11 2018-02-27 Dfine, Inc. System for use in treatment of vertebral fractures
US10478241B2 (en) 2016-10-27 2019-11-19 Merit Medical Systems, Inc. Articulating osteotome with cement delivery channel
US11344350B2 (en) 2016-10-27 2022-05-31 Dfine, Inc. Articulating osteotome with cement delivery channel and method of use
US11052237B2 (en) 2016-11-22 2021-07-06 Dfine, Inc. Swivel hub
US11026744B2 (en) 2016-11-28 2021-06-08 Dfine, Inc. Tumor ablation devices and related methods
US11116570B2 (en) 2016-11-28 2021-09-14 Dfine, Inc. Tumor ablation devices and related methods
US10463380B2 (en) 2016-12-09 2019-11-05 Dfine, Inc. Medical devices for treating hard tissues and related methods
US10470781B2 (en) 2016-12-09 2019-11-12 Dfine, Inc. Medical devices for treating hard tissues and related methods
US11540842B2 (en) 2016-12-09 2023-01-03 Dfine, Inc. Medical devices for treating hard tissues and related methods
US10660656B2 (en) 2017-01-06 2020-05-26 Dfine, Inc. Osteotome with a distal portion for simultaneous advancement and articulation
US11607230B2 (en) 2017-01-06 2023-03-21 Dfine, Inc. Osteotome with a distal portion for simultaneous advancement and articulation
US11510723B2 (en) 2018-11-08 2022-11-29 Dfine, Inc. Tumor ablation device and related systems and methods
US11937864B2 (en) 2018-11-08 2024-03-26 Dfine, Inc. Ablation systems with parameter-based modulation and related devices and methods

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JP4916629B2 (en) 2012-04-18
EP1181896A1 (en) 2002-02-27
US6669692B1 (en) 2003-12-30
JP2002113014A (en) 2002-04-16
US6986769B2 (en) 2006-01-17
US20040054369A1 (en) 2004-03-18

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