US20050149084A1 - Ablation burr - Google Patents

Ablation burr Download PDF

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Publication number
US20050149084A1
US20050149084A1 US11/070,446 US7044605A US2005149084A1 US 20050149084 A1 US20050149084 A1 US 20050149084A1 US 7044605 A US7044605 A US 7044605A US 2005149084 A1 US2005149084 A1 US 2005149084A1
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US
United States
Prior art keywords
burr
catheter
drive shaft
distal end
shaft
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US11/070,446
Inventor
Bill Kanz
Denise Drummond
Robert Barry
Paul Hirst
Mark Wyzgala
Gary Swinford
Edward Wulfman
Tom Clement
Tom Kadavy
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Boston Scientific Scimed Inc
Original Assignee
Scimed Life Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scimed Life Systems Inc filed Critical Scimed Life Systems Inc
Priority to US11/070,446 priority Critical patent/US20050149084A1/en
Publication of US20050149084A1 publication Critical patent/US20050149084A1/en
Assigned to BOSTON SCIENTIFIC SCIMED, INC. reassignment BOSTON SCIENTIFIC SCIMED, INC. CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: SCIMED LIFE SYSTEMS, INC.
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/3205Excision instruments
    • A61B17/3207Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A61B17/320758Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with a rotating cutting instrument, e.g. motor driven
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/3205Excision instruments
    • A61B17/3207Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A61B17/320725Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with radially expandable cutting or abrading elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00292Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
    • A61B2017/003Steerable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00535Surgical instruments, devices or methods, e.g. tourniquets pneumatically or hydraulically operated
    • A61B2017/00557Surgical instruments, devices or methods, e.g. tourniquets pneumatically or hydraulically operated inflatable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831Material properties
    • A61B2017/00867Material properties shape memory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B2017/320004Surgical cutting instruments abrasive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/3205Excision instruments
    • A61B17/3207Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A61B2017/320733Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with a flexible cutting or scraping element, e.g. with a whip-like distal filament member
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/3205Excision instruments
    • A61B17/3207Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A61B17/320758Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with a rotating cutting instrument, e.g. motor driven
    • A61B2017/320766Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with a rotating cutting instrument, e.g. motor driven eccentric

Definitions

  • the present invention generally relates to constructions for intravascular treatment devices useful for removing vascular occlusion material from a vascular occlusion or from a vascular lumen.
  • the invention more specifically relates to “expandable” intravascular occlusion material removal devices, as well as to methods of using those devices to treat vascular diseases.
  • “expandable” means that the burr can ablate a lumen having a larger diameter than the diameter of the lumen of the guide catheter to which the burr is advanced.
  • Vascular diseases such as atherosclerosis and the like, have become quite prevalent in the modern day. These diseases may present themselves in a number of forms. Each form of vascular disease may require a different method of treatment to reduce or cure the harmful effects of the disease.
  • Vascular diseases may take the form of deposits or growths in a patient's vasculature which may restrict, in the case of a partial occlusion, or stop, in the case of a total occlusion, blood flow to a certain portion of the patient's body. This can be particularly serious if, for example, such an occlusion occurs in a portion of the vasculature that supplies vital organs with blood or other necessary fluids.
  • a number of different therapies are being developed. While a number of invasive therapies are available, it is desirable to develop non-invasive therapies as well. Minimally invasive therapies may be less risky than invasive ones, and may be more welcomed by the patient because of the possibility of decreased chances of infection, reduced post-operative pain, and less post-operative rehabilitation.
  • One type of non-invasive therapy for vascular diseases is pharmaceutical in nature. Clot-busting drugs have been employed to help break up blood clots which may be blocking a particular vascular lumen. Other drug therapies are also available.
  • minimally invasive intravascular treatments exist that are not only pharmaceutical, but also revascularize blood vessels or lumens by mechanical means. Two examples of such intravascular therapies are balloon angioplasty and atherectomy which physically revascularize a portion of a patient's vasculature.
  • Balloon angioplasty comprises a procedure wherein a balloon catheter is inserted intravascularly into a patient through a relatively small puncture, which may be located proximate the groin, and intravascularly navigated by a treating physician to the occluded vascular site.
  • the balloon catheter includes a balloon or dilating member which is placed adjacent the vascular occlusion and then is inflated. Intravascular inflation of the dilating member by sufficient pressures, on the order of 5 to 12 atmospheres or so, causes the balloon to displace the occluding matter to revascularize the occluded lumen and thereby restore substantially normal blood flow through the revascularized portion of the vasculature. It is to be noted, however, that this procedure does not remove the occluding matter from the patient's vasculature, but displaces it.
  • occlusions may be difficult to treat with angioplasty.
  • some intravascular occlusions may be composed of an irregular, loose or heavily calcified material which may extend relatively far along a vessel or may extend adjacent a side branching vessel, and thus are not prone or susceptible to angioplastic treatment. Even if angioplasty is successful, thereby revascularizing the vessel and substantially restoring normal blood flow therethrough, there is a chance that the occlusion may recur. Recurrence of an occlusion may require repeated or alternative treatments given at the same intravascular site.
  • One such alternative mechanical treatment method involves removal, not displacement, as is the case with balloon angioplasty, of the material occluding a vascular lumen.
  • Such treatment devices sometimes referred to as atherectomy devices, use a variety of means, such as lasers, and rotating cutters or ablaters, for example, to remove the occluding material.
  • the rotating cutters may be particularly useful in removing certain vascular occlusions. Since vascular occlusions may have different compositions and morphology or shape, a given removal or cutting element may not be suitable for removal of a certain occlusion.
  • a given removal element may be suitable for removing only one of the occlusions.
  • Suitability of a particular cutting element may be determined by, for example, its size or shape.
  • a treating physician may have to use a plurality of different treatment devices to provide the patient with complete treatment. This type of procedure can be quite expensive because multiple pieces of equipment may need to be used (such intravascular devices are not reusable because they are inserted directly into the blood stream), and may be tedious to perform because multiple pieces of equipment must be navigated through an often-tortuous vascular path to the treatment site.
  • the present invention pertains generally to devices for performing atherectomy.
  • various embodiments of an atherectomy device are disclosed which can ablate a lumen having a larger diameter than the diameter of the lumen of the guide catheter through which the device is advanced.
  • an elongate shaft having a proximal and a distal end.
  • the shaft defines a lumen.
  • a burr deflector is disposed at the distal end of the shaft.
  • the burr deflector includes a burr engaging surface.
  • An elongate rotatable drive shaft extends through the lumen of the first shaft.
  • the drive shaft has a proximal end and a distal end.
  • a burr is disposed at the distal end of the drive shaft.
  • the drive shaft and burr are shiftable relative to the burr deflector.
  • the drive shaft and burr may be shifted between a first position and a second position, wherein the burr is transversely shifted relative to the burr deflector.
  • the deflection is co-linear to the length of the drive shaft.
  • the burr engaging surface is preferably disposed at an acute angle to the length of the first shaft.
  • the burr preferably includes an engaging surface disposed at an acute angle relative to the drive shaft such that the engaging surfaces provide a path along which the burr can shift transversely relative to the burr deflector.
  • an elongate shaft which has a proximal and a distal end.
  • the shaft defines a lumen.
  • An elongate rotatable drive shaft extends through the lumen.
  • the drive shaft has a proximal end and a distal end.
  • a burr is disposed at the distal end of the drive shaft.
  • a bushing is disposed around the drive shaft proximate the burr.
  • a steering line is connected to the bushing. The steering line can be pulled by an operator to shift the bushing and thus the burr and drive transversely.
  • an elongate rotatable drive shaft having a proximal and a distal end.
  • An ablation burr is disposed at the distal end of the drive shaft.
  • the ablation burr includes a mechanism which expands transversely in response to the centrifugal force generated when the burr rotates.
  • the mechanism is generally tubular and has a proximal end and a distal end constrained against expansion. The central portion of the tubular member is allowed to expand under the influence of the centrifugal force.
  • a member having a generally helical cross-section is provided which tends to unwind, increasing its transverse diameter as the burr rotates.
  • a line is provided having a proximal end and a distal end. The ends of the line are held a distance apart less than the length of the line. An abrasive is disposed on the line. As the burr is rotated, the line moves transversely.
  • the mechanism includes a plurality of bristles which can shift transversely under the influence of centrifugal force.
  • an elongate rotatable drive shaft having a proximal end and a distal end.
  • a lumen is defined through the elongate drive shaft.
  • a balloon including an outer surface and defining a balloon enclosure in fluid communication with the inflation lumen is disposed at the distal end of the drive shaft.
  • An abrasive is disposed on the outer surface of the balloon. The balloon can be dilated by pressure or centrifugal force to increase the transverse dimension of the abrasive surface.
  • an elongate shaft having a proximal end and a distal end.
  • the shaft defines a drive shaft lumen and an inflation lumen.
  • a rotatable drive shaft having a proximal end and a distal end, is disposed in the drive shaft lumen.
  • An ablating burr is disposed at the distal end of the drive shaft.
  • a balloon is disposed eccentrically on the drive shaft proximate the burr. The balloon can be inflated to push against the vessel wall and shift the drive shaft and burr transversely within the vessel lumen.
  • an elongate rotatable drive shaft having a proximal end and a distal end.
  • An ablation burr is eccentrically connected to the drive shaft at the distal end of the shaft.
  • a counterweight is disposed on the burr to place the center of mass of the burr in line with the longitudinal axis of the drive shaft. The presence of the counterweight dampens whipping of the burr which might otherwise occur during rotation of the drive shaft.
  • an elongate shaft having a proximal end and a distal end.
  • the shaft defines a lumen therethrough.
  • a rotatable drive shaft having a proximal end and a distal end, is disposed through the lumen.
  • a burr, including a plurality of spring members is disposed at the distal end of the drive.
  • the drive shaft and the burr are shiftable between a first position and a second position. In the first position, the spring members are disposed at least in part within the lumen of the first shaft and are transversely constrained thereby. In the second position, the spring members are transversely restrained less than in the first position such that the burr has a greater transverse dimension in the second position than in the first position.
  • an elongate rotatable drive shaft having a proximal end and a distal end, the drive shaft includes a generally helical-shaped portion proximate the distal end biased to expand when unconstrained.
  • An abrasive is disposed on the helical portion.
  • the helical portion can be advanced to the site where atherectomy will be performed in a constrained and collapsed state through a guide catheter. When the helical shaped portion exits the guide catheter, the helically shaped portion, then unconstrained, will expand transversely.
  • FIG. 1 is a side view of a catheter assembly in accordance with the present invention
  • FIG. 2 is a side view of another embodiment of a catheter in accordance with the present invention.
  • FIG. 3 is a side view of yet another embodiment of the catheter in accordance with the present invention.
  • FIG. 4 is a longitudinal, cross-sectional view of yet another embodiment of the catheter in accordance with the present invention.
  • FIG. 5 is a fragmentary, cross-sectional view of yet another catheter in accordance with the present invention.
  • FIG. 6 is a side view of yet another embodiment of the catheter in accordance with the present invention.
  • FIG. 7 is a side view of yet another embodiment of the catheter in accordance with the present invention.
  • FIG. 8 is a side view of yet another embodiment of the catheter in accordance with the present invention.
  • FIG. 9 is a perspective view of yet another embodiment of the catheter in accordance with the present invention.
  • FIG. 10 is a perspective view of yet another embodiment of the catheter in accordance with the present invention.
  • FIG. 11 is a side view of yet another embodiment of the catheter in accordance with the present invention.
  • FIG. 12 is a side view of yet another embodiment of the catheter in accordance with the present invention.
  • FIG. 13 is a view of the embodiment of FIG. 12 in use
  • FIG. 14 is a side view of yet another embodiment of the catheter in accordance with the present invention.
  • FIG. 15 is a side view of yet another embodiment of the catheter in accordance with the present invention.
  • FIG. 16 is a distal end view of the catheter of FIG. 15 ;
  • FIG. 17 is a cross-sectional view of the catheter of FIG. 15 ;
  • FIG. 18 is a side view of yet another embodiment of the catheter in accordance with the present invention.
  • FIG. 19 is a cross-sectional view of yet another embodiment of the catheter in accordance with the present invention.
  • FIGS. 1 is a side view of catheter 10 in accordance with the present invention.
  • catheter 10 is disposed within vessel 12 proximate a plaque deposit 14 .
  • Catheter 10 includes an elongate shaft 16 .
  • Shaft 16 includes an outer shaft 18 having a proximal end a distal end and defining a drive shaft lumen therethrough.
  • Catheter 16 also includes a drive shaft 20 having a proximal end a distal end and extending through outer shaft 18 .
  • Disposed at the distal end of outer shaft 18 is a burr deflector 22 having a burr engaging surface 24 .
  • Disposed at the distal end of drive shaft 20 is a burr 26 rotatable by drive shaft 20 , and including an abrasive surface 28 .
  • suitable manifold and motor can be provided at the proximal end of catheter 10 to rotate burr 26 and facilitate the uses of catheter 10 as herein described.
  • catheter 10 can be provided at the proximal end of catheter 10 to rotate burr 26 and facilitate the uses of catheter 10 as herein described.
  • suitable manifold and motor can be provided at the proximal end of catheter 10 to rotate burr 26 and facilitate the uses of catheter 10 as herein described.
  • Those skilled in the art will appreciate the various biocompatible materials available to construct catheter 10 including burr 26 . This is also true with respect to the various embodiments of the catheters discussed below.
  • manifold, motor, infusion displays control mechanisms and other devices that can advantageously be connected to the proximal ends of the catheter to facilitate their use. Additionally, those skilled in the art will recognize various biocompatible materials, and methods available to construct each embodiment.
  • catheter 10 is advanced percutaneously to a coronary lesion including plaque 14 .
  • Burr 26 is advanced to plaque as shown by the arrow parallel to shaft 16 .
  • Burr 26 is then rotated by drive shaft 26 as shown by the arrows such that plaque deposit 14 is grounded to micro fine particles.
  • Catheter 10 can be advanced to the lesion through a guide catheter (not shown) having an inner lumen at least slightly greater in diameter than the diameter of burr 26 .
  • the inside diameter of vessel 12 is greater than the diameter of burr 26 .
  • shaft 10 can be drawn proximally to engage burr 26 against burr deflector surface 24 .
  • burr 26 As burr 26 is forced into surface 24 it will tend to slide proximally along surface 24 while simultaneously being displaced transversely as shown by the arrow on burr 26 .
  • the greater the transverse dimension of surface 24 the greater is the possible transverse movement of burr 26 .
  • the transverse movement of burr 26 is preferably co-linear with the length of the drive shaft.
  • FIG. 2 is a view of an alternate embodiment of an atherectomy catheter 50 in accordance with the present invention.
  • Catheter 50 includes an elongate shaft 56 including an outer shaft 58 defining a drive shaft lumen therethrough.
  • a drive shaft 60 extends through the lumen.
  • Drive shaft 60 includes a proximal end and a distal end.
  • Disposed at the distal end of drive shaft 60 is a burr 66 having an abrasive coating 68 .
  • a bushing 70 Disposed around a proximal portion of burr 66 is a bushing 70 .
  • Bushing 70 can include an inwardly disposed circumferential flange which engages a circumferential groove (not shown) in burr 66 such that bushing 70 is fixedly connected to burr 66 , yet burr 66 can rotate within bushing 70 .
  • Catheter 50 can be used as described above with respect to catheter 10 .
  • burr 60 can be shifted from side to side by pulling proximally a steering wire 72 or 74 .
  • Pulling steering wire 74 proximally as steering wire 72 is allowed to move distally will shift burr 66 transversely toward wire 74 as shown by the arrow on burr 66 .
  • burr 66 can be shifted transversely in the opposite direction by pulling steering wire 72 proximally while allowing wires 74 to shift distally.
  • catheter 50 can be advanced to percutaneously to the cite of the lesion through a guide catheter having an inside diameter at least slightly greater than the transverse diameter of burr 66 .
  • Burr 66 can be rotated as shown by the arrow proximate drive shaft 60 and be engaged with the lesion. Burr 66 can be moved transversely by steering wires 72 and 74 as necessary to remove the plaque.
  • FIG. 3 is a view of yet another embodiment of an atherectomy catheter 110 in accordance with the present invention.
  • Catheter 110 includes an elongate drive shaft 120 having a proximal end and distal end.
  • Drive shaft 120 defines a lumen 121 therethrough.
  • burr 126 Disposed at the distal end of drive shaft 120 is burr 126 having an abrasive coating 128 .
  • Burr 126 includes a generally tubularly shaped member 130 connected to burr 126 at the member's proximal and distal ends.
  • Burr 126 includes lumens 132 in fluid communication with lumen 121 of shaft 120 . Lumens 132 lead from lumen 121 to the inside surface of member 130 .
  • catheter 110 is advanced to a lesion as described above with respect to the other catheter embodiments.
  • the tubular member 130 of burr 126 is sufficiently elastic to stretch transversely under the influence of centrifugal force when tip 126 is rotated by shaft 120 . Rotation of tip 126 , thus will move tubular member 130 from a first position A to a second position B. In second position B, burr 126 can ablate a larger diameter path. While member 130 is moving from position A to position B, fluid may be introduced through lumens 121 and 132 as shown by the arrows into the space created inside member 130 .
  • FIG. 4 is a cross-sectional view of yet another embodiment of a catheter 150 in accordance with the present invention.
  • Catheter 150 includes an elongate shaft 156 defining an inflation lumen 157 .
  • a balloon 166 Disposed proximate the proximal end of shaft 156 is a balloon 166 defining a burr having an abrasive coating 168 .
  • Catheter 150 can include a manifold 176 including lumens 178 in fluid communication with lumen 157 and the interior space of balloon 166 .
  • balloon 166 is advanced percutaneously to a lesion. At the lesion, balloon 166 is inflated to increase its diameter. Abrasive surface 168 is then advanced into engagement with the plaque. Balloon 166 is then rotated to abrade plaque.
  • FIG. 5 is a partial, cross-sectional view of yet another embodiment of a catheter 210 in accordance with the present invention.
  • Catheter 210 includes an elongate drive shaft 220 having a proximal end and a distal end.
  • a burr 226 is disposed at the distal end of drive shaft 220 .
  • Burr 226 includes an abrasive coating 228 and a distal flexible portion or skirt 229 which is free to move generally transversely under the influence of centrifugal force as burr 226 is rotated by shaft 220 .
  • the arrows proximate skirt 229 show that the direction of the generally transverse movement of skirt 229 to increase the effective diameter of burr 226 .
  • burr 226 shows the rotation of burr 226 . While burr 226 is not rotating skirt 229 can be disposed generally parallel to shaft 220 and then elastically stretch to the position shown in FIG. 5 when burr 226 is rotated.
  • FIG. 6 is a side view of yet another alternate embodiment of a catheter 250 in accordance with the present invention.
  • Catheter 250 is shown disposed within a vessel lumen 252 .
  • Catheter 250 includes an elongate shaft 256 having a proximal end and a distal end.
  • Catheter 256 includes an outer shaft 258 which defines the drive shaft lumen and two inflation lumens 261 .
  • An elongate drive shaft 260 is disposed through the drive shaft lumen.
  • a cup shaped bearing 265 is disposed at the distal end of shaft 256 .
  • a burr 266 is connected to the distal end of drive shaft 260 .
  • the distal end of burr 266 can include an abrasive coating 268 .
  • the proximal end of burr 266 can be nested within bearing 265 .
  • Balloons 263 Connected to shaft 258 proximate burr 266 are balloons 263 .
  • Balloons 263 define a balloon envelope in fluid communication with inflation lumens 261 . Additional balloons may be used to increase the positional control of burr 266 .
  • Catheter 250 is advanced as described above with respect to the alternate embodiments in accordance with the present invention to perform the atherectomy procedure. Likewise, burr 266 is rotated to abrade plaque. In order to shift burr 266 transversely within lumen 252 , balloons 263 may be alternately inflated or deflated to engage the wall of vessel 252 forcing burr 266 transversely in a direction opposite the resultant force of balloons 263 incident the wall of vessel 252 .
  • FIG. 7 is a side view of yet another embodiment of a catheter 310 in accordance with the present invention.
  • Catheter 310 includes an elongate shaft 320 .
  • Shaft 320 includes a proximal end and a distal end.
  • a burr 326 is disposed eccentrically on shaft 320 proximate the distal end of shaft 320 .
  • Burr 326 includes an abrasive coating 328 .
  • a counterweight 327 is disposed in burr 326 . The counterweight has a weight sufficient to shift the center of mass of burr 326 such that it lies generally on the longitudinal axis of shaft 320 .
  • the effect of counterweighting can also be achieved by an asymmetrical shaping of the burr and/or creating voids in the burr to shift the distribution of the burrs weight.
  • This allows burr 326 to be rotated by shaft 320 through a position A and B as shown without whipping the distal end of shaft 322 .
  • By eccentrically mounting burr 326 on shaft 320 it can be appreciated by reference to positions A and B that a larger area can be circumscribed by the surface of burr 326 as burr 326 is rotated by shaft 320 than if the burr were rotated about its central axis.
  • FIG. 8 is a view of yet another embodiment of a catheter 350 in accordance with the present invention.
  • Catheter 350 includes an elongate shaft 356 .
  • Shaft 356 includes an outer shaft 358 having a proximal end and a distal end and defining a drive shaft lumen therethrough.
  • Shaft 356 also includes a drive shaft 360 disposed through the drive shaft lumen.
  • a cone-shaped bearing 365 is preferably disposed at the distal end of shaft 358 .
  • Bearing 356 has a lumen extending longitudinally therethrough, and having a diameter which generally increases distally.
  • a burr 366 is disposed at the distal end of drive shaft 360 . Burr 366 can have an abrasive coating (not shown).
  • Burr 366 is preferably formed from a plurality of spring members 380 joined at their respective proximal and distal ends. Members 380 are preferably preformed to assume a transversely expanded shape when unconstrained. The diameter of burr 366 can be reduced by withdrawing burr 366 at least in part into bearing 365 . Burr 366 may be withdrawn at least partially into bearing 365 by shifting drive shaft 360 proximally relative to outer shaft 358 . Burr 366 can be advanced to the cite of a lesion in the constrained configuration and then expanded, and rotated to abrade plaque.
  • FIG. 9 is an embodiment of yet another catheter 410 in accordance with the present invention.
  • Catheter 410 includes a drive shaft 420 having a proximal end and a distal end.
  • a generally spiral shaped ablation burr 434 is disposed at the distal end of drive shaft 420 .
  • Burr 434 can include an abrasive coating (not shown). Upon rotation of drive shaft 420 , burr 434 can generally expand or unwind from a position A to a position B under the influence of centrifugal force.
  • Burr 434 as shown has a generally circular cross section. Burr 434 can have a generally rectangular cross section if burr 434 were formed from a ribbon shaped member.
  • FIG. 10 is a view of yet another embodiment of a catheter 450 in accordance with the present invention.
  • Catheter 450 includes an elongate drive shaft 460 having a proximal end and a distal end.
  • a burr 466 is disposed proximate the distal end of shaft 460 .
  • Burr 466 can include an abrasive coating 468 .
  • a coil 482 can be formed in drive shaft 460 proximate burr 466 .
  • Abrasive coating 484 can be deposited on coil 482 .
  • Abrasive coating 484 can be deposited in the configuration and plurality of burrs. Coil 482 can be stretched and flattened to be advanced through a guide catheter. As the coil portion of drive shaft 460 is advanced distally from a guide catheter, that portion of drive shaft 460 resumes the coil shape shown in FIG. 10 .
  • FIG. 11 is a view of yet another catheter 510 in accordance with the present invention.
  • Catheter 510 includes drive shaft 520 having a proximal end and a distal end.
  • a burr 526 is disposed at the distal end of drive shaft 520 .
  • Burr 526 preferably includes an abrasive coating 528 .
  • Burr 526 is preferably formed from a generally tubular member 541 which is sealed at its distal end to form an abrasive tip 543 .
  • Longitudinal slits 540 are formed in the proximal end of tubular member 541 such that leaves 542 are disposed therebetween. When burr 526 is rotated, leaves 542 will move from a first position A to a second position B under the influence of centrifugal force.
  • FIG. 12 is a view of yet another embodiment of a catheter 550 in accordance with the present invention.
  • Catheter 550 includes an elongate drive shaft 560 having a proximal end and a distal end. Proximate the distal end of drive shaft 560 is a line 586 having a proximal end and a distal end. The proximal end and distal ends of line 586 are connected to drive shaft 560 at a spaced distance less than the length of line 586 .
  • Abrasive burrs 588 are deposited along line 586 .
  • line 586 is in a first position A.
  • line 586 is shown in a second position B wherein line 586 is shift transversely under the influence of centrifugal force as drive shaft 560 is rotated.
  • FIG. 14 is a view of yet another catheter 610 in accordance with the present invention.
  • Catheter 610 includes a drive shaft 620 having a proximal end and a distal end.
  • a burr 626 is disposed proximate the distal end of shaft 620 .
  • Burr 626 preferably includes an abrasive coating 628 .
  • a plurality of bristles extend from burr 626 .
  • Disposed at the outside end of each bristle 636 is a burr end 638 which may include an abrasive coating.
  • Bristles 636 can be configured to move from first position A to second position B under the influence of centrifugal force as burr 626 is rotated. Alternately, bristles 633 may be biased to expand between positions A and B upon becoming unconstrained as they are advanced from a guide catheter.
  • FIG. 15 is a side view of yet another catheter 650 in accordance with the present invention.
  • Catheter 650 includes an elongate drive shaft 656 which can include a proximal, helical shaft encased in a polymer.
  • Shaft 656 can also include a distal shaft portion 659 around which is disposed an elastomeric balloon 667 .
  • Elastomeric balloon 667 includes a distal portion which is folded over into folds or leaflets 669 .
  • the distal end of catheter 650 including the folded region of balloon 667 is preferably coated with an abrasive.
  • FIG. 16 is a view of the distal end of catheter 650 of FIG. 15 and offers an alternate view of folds 669 .
  • FIG. 17 is a cross-sectional view of catheter 650 of FIG. 15 .
  • the arrow to the right of the figure shows the direction of rotation of balloon 667 .
  • the balloon's distal portion including leaves 669 expands from a first position A to a second position B.
  • the space defined between the balloon inner surface and shaft 659 is preferably preloaded with a fluid such as saline prior to advancement to the site of the lesion.
  • the quantity of fluid preloaded into balloon 667 is such that when balloon 667 is not rotated, it will be in a relatively reduced diameter, i.e., position A.
  • the fluid with shift by centrifugal force into that distal portion of balloon 667 including leaves 669 expanding balloon 667 into the increased diameter configuration of position B.
  • FIG. 18 shows yet another alternate embodiment of a catheter 710 in accordance with the present invention.
  • Catheter 710 has an elongate shaft 716 having a proximal end a distal end.
  • Shaft 716 includes an outer sheath 718 defining a drive shaft lumen therethrough.
  • Shaft 716 includes an elongate drive shaft 720 disposed through the lumen.
  • Sheath 718 includes a distal bearing surface which preferably defines a lumen having an inside diameter increasing distally.
  • Disposed at the distal end of drive shaft 720 is an expandable burr 726 which preferably has an abrasive coating (not shown). Burr 726 can be formed from a plurality of spring member similar to the spring members 380 of catheter 350 shown in FIG. 8 . For clarity, in FIG. 18 , only two spring members 740 are shown.
  • Shell 742 preferably encloses a main body 743 and unidirectional ratchet 744 including reverse positive stop 746 .
  • a threaded member 800 is threaded into a sleeve 745 .
  • Threaded member 800 is fixably connected at its distal end to stop 746 and fixably connected at its proximal end to forward motion positive stop 747 .
  • Threaded member 800 is also fixably connected to drive shaft 720 .
  • Spring members 740 are connected at their proximal ends to sleeve 745 and fixably held in position by collar 748 .
  • spring members 740 are fixably connected to the distal end of main body 743 .
  • Main body 743 is connected at its proximal end about a pin 804 to ratchet 744 .
  • Ratchet 744 includes teeth 802 and the main body portion includes teeth 806 .
  • Teeth 802 and 806 are shown in FIG. 8 meshed along angled surfaces 808 and longitudinally extended surfaces 810 .
  • ratchet 744 and main body 743 can be used to control the transverse diameter D of burr 726 .
  • a burr advancable through an 8F guide catheter could be expanded between 2.0 mm and 3.5 mm in diameter, at 0.25 mm intervals or steps.
  • the ability to control the diameter of burrs 726 at such steps can be considered indexing.
  • drive shaft 720 can be rotated such that teeth 802 and 806 engage each other along surfaces 808 . Since surfaces 808 are inclined, teeth 806 will tend to rise out from between 802 momentarily increasing the length of burr 726 . As drive shaft 720 continues to rotate, the teeth will index and reengage the adjacent teeth.
  • burr 726 can be kept from rotating during indexing by engagement with sheath 718 or the vessel or vessel lesion.
  • burr 726 can be reduced by merely withdrawing it at least in part into sheath 718 .
  • Burr 726 can be withdrawn into sheath 718 sufficiently such that teeth 802 and 806 will be unmeshed.
  • drive shaft 720 can be rotated to advance stop 747 to sleeve 745 .
  • burr 726 is reset to index from its smallest indexing diameter to its largest as described above.
  • FIG. 19 is a cross-sectional view of yet another embodiment of a catheter 750 in accordance with the present invention.
  • Catheter 750 includes an elongate drive shaft 760 having a proximal end and a distal end.
  • Drive shaft 760 can be, for example, formed from a helical member surrounded by a polymer sheath.
  • a burr 766 is disposed at the distal end of shaft 760 connected to burr 766 is a loosely spiraled ribbon member 767 which has a reduced length and width as it spirals outwardly from shaft 760 .
  • Abrasive coating 768 can also be applied to ribbon member 767 .
  • ribbon member 767 will tend to unwind and expand transversely when rotated in one direction.

Abstract

A catheter including an elongate drive shaft having a proximal end and a distal end, an ablation burr disposed at the distal end expandable between a first position and a second position, wherein in the second position has a greater transverse dimension than in the first position. The catheter of the present invention can include a mechanism for positioning the burr eccentrically within a vessel lumen. In this context, expansion means that the burr can ablate a lumen having a larger diameter than the diameter of the lumen of the guide catheter to which the device is advanced.

Description

    BACKGROUND OF THE INVENTION
  • The present invention generally relates to constructions for intravascular treatment devices useful for removing vascular occlusion material from a vascular occlusion or from a vascular lumen. The invention more specifically relates to “expandable” intravascular occlusion material removal devices, as well as to methods of using those devices to treat vascular diseases. In this context, “expandable” means that the burr can ablate a lumen having a larger diameter than the diameter of the lumen of the guide catheter to which the burr is advanced.
  • Vascular diseases, such as atherosclerosis and the like, have become quite prevalent in the modern day. These diseases may present themselves in a number of forms. Each form of vascular disease may require a different method of treatment to reduce or cure the harmful effects of the disease. Vascular diseases, for example, may take the form of deposits or growths in a patient's vasculature which may restrict, in the case of a partial occlusion, or stop, in the case of a total occlusion, blood flow to a certain portion of the patient's body. This can be particularly serious if, for example, such an occlusion occurs in a portion of the vasculature that supplies vital organs with blood or other necessary fluids.
  • To treat these diseases, a number of different therapies are being developed. While a number of invasive therapies are available, it is desirable to develop non-invasive therapies as well. Minimally invasive therapies may be less risky than invasive ones, and may be more welcomed by the patient because of the possibility of decreased chances of infection, reduced post-operative pain, and less post-operative rehabilitation. One type of non-invasive therapy for vascular diseases is pharmaceutical in nature. Clot-busting drugs have been employed to help break up blood clots which may be blocking a particular vascular lumen. Other drug therapies are also available. Further, minimally invasive intravascular treatments exist that are not only pharmaceutical, but also revascularize blood vessels or lumens by mechanical means. Two examples of such intravascular therapies are balloon angioplasty and atherectomy which physically revascularize a portion of a patient's vasculature.
  • Balloon angioplasty comprises a procedure wherein a balloon catheter is inserted intravascularly into a patient through a relatively small puncture, which may be located proximate the groin, and intravascularly navigated by a treating physician to the occluded vascular site. The balloon catheter includes a balloon or dilating member which is placed adjacent the vascular occlusion and then is inflated. Intravascular inflation of the dilating member by sufficient pressures, on the order of 5 to 12 atmospheres or so, causes the balloon to displace the occluding matter to revascularize the occluded lumen and thereby restore substantially normal blood flow through the revascularized portion of the vasculature. It is to be noted, however, that this procedure does not remove the occluding matter from the patient's vasculature, but displaces it.
  • While balloon angioplasty is quite successful in substantially revascularizing many vascular lumens by reforming the occluding material, other occlusions may be difficult to treat with angioplasty. Specifically, some intravascular occlusions may be composed of an irregular, loose or heavily calcified material which may extend relatively far along a vessel or may extend adjacent a side branching vessel, and thus are not prone or susceptible to angioplastic treatment. Even if angioplasty is successful, thereby revascularizing the vessel and substantially restoring normal blood flow therethrough, there is a chance that the occlusion may recur. Recurrence of an occlusion may require repeated or alternative treatments given at the same intravascular site.
  • Accordingly, attempts have been made to develop other alternative mechanical methods of minimally invasive, intravascular treatment in an effort to provide another way of revascularizing an occluded vessel and of restoring blood flow through the relevant vasculature. These alternative treatments may have particular utility with certain vascular occlusions, or may provide added benefits to a patient when combined with balloon angioplasty and/or drug therapies.
  • One such alternative mechanical treatment method involves removal, not displacement, as is the case with balloon angioplasty, of the material occluding a vascular lumen. Such treatment devices, sometimes referred to as atherectomy devices, use a variety of means, such as lasers, and rotating cutters or ablaters, for example, to remove the occluding material. The rotating cutters may be particularly useful in removing certain vascular occlusions. Since vascular occlusions may have different compositions and morphology or shape, a given removal or cutting element may not be suitable for removal of a certain occlusion.
  • Alternatively, if a patient has multiple occlusions in his vasculature, a given removal element may be suitable for removing only one of the occlusions. Suitability of a particular cutting element may be determined by, for example, its size or shape. Thus, a treating physician may have to use a plurality of different treatment devices to provide the patient with complete treatment. This type of procedure can be quite expensive because multiple pieces of equipment may need to be used (such intravascular devices are not reusable because they are inserted directly into the blood stream), and may be tedious to perform because multiple pieces of equipment must be navigated through an often-tortuous vascular path to the treatment site.
  • SUMMARY OF THE INVENTION
  • The present invention pertains generally to devices for performing atherectomy. In particular, various embodiments of an atherectomy device are disclosed which can ablate a lumen having a larger diameter than the diameter of the lumen of the guide catheter through which the device is advanced.
  • In one embodiment, an elongate shaft is provided having a proximal and a distal end. The shaft defines a lumen. A burr deflector is disposed at the distal end of the shaft. The burr deflector includes a burr engaging surface. An elongate rotatable drive shaft extends through the lumen of the first shaft. The drive shaft has a proximal end and a distal end. A burr is disposed at the distal end of the drive shaft. The drive shaft and burr are shiftable relative to the burr deflector. The drive shaft and burr may be shifted between a first position and a second position, wherein the burr is transversely shifted relative to the burr deflector. Preferably, the deflection is co-linear to the length of the drive shaft.
  • The burr engaging surface is preferably disposed at an acute angle to the length of the first shaft. The burr preferably includes an engaging surface disposed at an acute angle relative to the drive shaft such that the engaging surfaces provide a path along which the burr can shift transversely relative to the burr deflector.
  • In yet another embodiment of a device in accordance with the present invention an elongate shaft is provided which has a proximal and a distal end. The shaft defines a lumen. An elongate rotatable drive shaft extends through the lumen. The drive shaft has a proximal end and a distal end. A burr is disposed at the distal end of the drive shaft. A bushing is disposed around the drive shaft proximate the burr. A steering line is connected to the bushing. The steering line can be pulled by an operator to shift the bushing and thus the burr and drive transversely.
  • In yet another embodiment of a device in accordance with the present invention, an elongate rotatable drive shaft is provided having a proximal and a distal end. An ablation burr is disposed at the distal end of the drive shaft. The ablation burr includes a mechanism which expands transversely in response to the centrifugal force generated when the burr rotates.
  • In one embodiment, the mechanism is generally tubular and has a proximal end and a distal end constrained against expansion. The central portion of the tubular member is allowed to expand under the influence of the centrifugal force. In yet another embodiment of the mechanism, a member having a generally helical cross-section is provided which tends to unwind, increasing its transverse diameter as the burr rotates. In yet another embodiment of the mechanism, a line is provided having a proximal end and a distal end. The ends of the line are held a distance apart less than the length of the line. An abrasive is disposed on the line. As the burr is rotated, the line moves transversely. In yet another embodiment of the mechanism includes a plurality of bristles which can shift transversely under the influence of centrifugal force.
  • In another embodiment of the atherectomy device in accordance with the present invention, an elongate rotatable drive shaft is provided having a proximal end and a distal end. A lumen is defined through the elongate drive shaft. A balloon including an outer surface and defining a balloon enclosure in fluid communication with the inflation lumen is disposed at the distal end of the drive shaft. An abrasive is disposed on the outer surface of the balloon. The balloon can be dilated by pressure or centrifugal force to increase the transverse dimension of the abrasive surface.
  • In yet another embodiment of an atherectomy device in accordance with the present invention, an elongate shaft is provided having a proximal end and a distal end. The shaft defines a drive shaft lumen and an inflation lumen. A rotatable drive shaft, having a proximal end and a distal end, is disposed in the drive shaft lumen. An ablating burr is disposed at the distal end of the drive shaft. A balloon is disposed eccentrically on the drive shaft proximate the burr. The balloon can be inflated to push against the vessel wall and shift the drive shaft and burr transversely within the vessel lumen.
  • In yet another embodiment of an atherectomy device in accordance with the present invention, an elongate rotatable drive shaft is provided having a proximal end and a distal end. An ablation burr is eccentrically connected to the drive shaft at the distal end of the shaft. A counterweight is disposed on the burr to place the center of mass of the burr in line with the longitudinal axis of the drive shaft. The presence of the counterweight dampens whipping of the burr which might otherwise occur during rotation of the drive shaft. This embodiment is related to that disclosed in U.S. patent application Ser. No. 08/987,969, filed Dec. 10, 1997 and entitled ASYMMETRIC BURRS FOR ROTATIONAL ABLATION incorporated herein by reference.
  • In yet another embodiment of the atherectomy device in accordance with the present invention, an elongate shaft is provided having a proximal end and a distal end. The shaft defines a lumen therethrough. A rotatable drive shaft having a proximal end and a distal end, is disposed through the lumen. A burr, including a plurality of spring members is disposed at the distal end of the drive. The drive shaft and the burr are shiftable between a first position and a second position. In the first position, the spring members are disposed at least in part within the lumen of the first shaft and are transversely constrained thereby. In the second position, the spring members are transversely restrained less than in the first position such that the burr has a greater transverse dimension in the second position than in the first position.
  • In yet another embodiment of an atherectomy device in accordance with the present invention, an elongate rotatable drive shaft is provided having a proximal end and a distal end, the drive shaft includes a generally helical-shaped portion proximate the distal end biased to expand when unconstrained. An abrasive is disposed on the helical portion. The helical portion can be advanced to the site where atherectomy will be performed in a constrained and collapsed state through a guide catheter. When the helical shaped portion exits the guide catheter, the helically shaped portion, then unconstrained, will expand transversely.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • FIG. 1 is a side view of a catheter assembly in accordance with the present invention;
  • FIG. 2 is a side view of another embodiment of a catheter in accordance with the present invention;
  • FIG. 3 is a side view of yet another embodiment of the catheter in accordance with the present invention;
  • FIG. 4 is a longitudinal, cross-sectional view of yet another embodiment of the catheter in accordance with the present invention;
  • FIG. 5 is a fragmentary, cross-sectional view of yet another catheter in accordance with the present invention;
  • FIG. 6 is a side view of yet another embodiment of the catheter in accordance with the present invention;
  • FIG. 7 is a side view of yet another embodiment of the catheter in accordance with the present invention;
  • FIG. 8 is a side view of yet another embodiment of the catheter in accordance with the present invention;
  • FIG. 9 is a perspective view of yet another embodiment of the catheter in accordance with the present invention;
  • FIG. 10 is a perspective view of yet another embodiment of the catheter in accordance with the present invention;
  • FIG. 11 is a side view of yet another embodiment of the catheter in accordance with the present invention;
  • FIG. 12 is a side view of yet another embodiment of the catheter in accordance with the present invention;
  • FIG. 13 is a view of the embodiment of FIG. 12 in use;
  • FIG. 14 is a side view of yet another embodiment of the catheter in accordance with the present invention;
  • FIG. 15 is a side view of yet another embodiment of the catheter in accordance with the present invention;
  • FIG. 16 is a distal end view of the catheter of FIG. 15;
  • FIG. 17 is a cross-sectional view of the catheter of FIG. 15;
  • FIG. 18 is a side view of yet another embodiment of the catheter in accordance with the present invention; and
  • FIG. 19 is a cross-sectional view of yet another embodiment of the catheter in accordance with the present invention.
  • DETAILED DESCRIPTION OF THE INVENTION
  • Referring now to the drawings, wherein like reference numerals refer to like reference elements throughout the several views, FIGS. 1 is a side view of catheter 10 in accordance with the present invention. As shown in FIG. 1, catheter 10 is disposed within vessel 12 proximate a plaque deposit 14. Catheter 10 includes an elongate shaft 16. Shaft 16 includes an outer shaft 18 having a proximal end a distal end and defining a drive shaft lumen therethrough. Catheter 16 also includes a drive shaft 20 having a proximal end a distal end and extending through outer shaft 18. Disposed at the distal end of outer shaft 18 is a burr deflector 22 having a burr engaging surface 24. Disposed at the distal end of drive shaft 20 is a burr 26 rotatable by drive shaft 20, and including an abrasive surface 28.
  • As will be appreciated by those skilled in the art, suitable manifold and motor can be provided at the proximal end of catheter 10 to rotate burr 26 and facilitate the uses of catheter 10 as herein described. Those skilled in the art will appreciate the various biocompatible materials available to construct catheter 10 including burr 26. This is also true with respect to the various embodiments of the catheters discussed below. Those skilled in the art will recognize the various manifold, motor, infusion displays control mechanisms and other devices that can advantageously be connected to the proximal ends of the catheter to facilitate their use. Additionally, those skilled in the art will recognize various biocompatible materials, and methods available to construct each embodiment.
  • In use, catheter 10 is advanced percutaneously to a coronary lesion including plaque 14. Burr 26 is advanced to plaque as shown by the arrow parallel to shaft 16. Burr 26 is then rotated by drive shaft 26 as shown by the arrows such that plaque deposit 14 is grounded to micro fine particles. Catheter 10 can be advanced to the lesion through a guide catheter (not shown) having an inner lumen at least slightly greater in diameter than the diameter of burr 26.
  • As shown in FIG. 1, the inside diameter of vessel 12 is greater than the diameter of burr 26. In order for burr 26 to be positioned within vessel 12, to remove plaque 14, shaft 10 can be drawn proximally to engage burr 26 against burr deflector surface 24. As burr 26 is forced into surface 24 it will tend to slide proximally along surface 24 while simultaneously being displaced transversely as shown by the arrow on burr 26. The greater the transverse dimension of surface 24, the greater is the possible transverse movement of burr 26. The transverse movement of burr 26 is preferably co-linear with the length of the drive shaft.
  • FIG. 2 is a view of an alternate embodiment of an atherectomy catheter 50 in accordance with the present invention. Catheter 50 includes an elongate shaft 56 including an outer shaft 58 defining a drive shaft lumen therethrough. A drive shaft 60 extends through the lumen. Drive shaft 60 includes a proximal end and a distal end. Disposed at the distal end of drive shaft 60 is a burr 66 having an abrasive coating 68. Disposed around a proximal portion of burr 66 is a bushing 70. Bushing 70 can include an inwardly disposed circumferential flange which engages a circumferential groove (not shown) in burr 66 such that bushing 70 is fixedly connected to burr 66, yet burr 66 can rotate within bushing 70. Connected to opposite sides of bushing 70 and extending proximally through shaft 58 are steering wires 72 and 74.
  • Catheter 50 can be used as described above with respect to catheter 10. Unlike catheter 10, however, rather than having a burr deflector 22 to transversely move burr 26, burr 60 can be shifted from side to side by pulling proximally a steering wire 72 or 74. Pulling steering wire 74 proximally as steering wire 72 is allowed to move distally will shift burr 66 transversely toward wire 74 as shown by the arrow on burr 66. Similarly, burr 66 can be shifted transversely in the opposite direction by pulling steering wire 72 proximally while allowing wires 74 to shift distally.
  • To perform an atherectomy procedure using catheter 50, catheter 50 can be advanced to percutaneously to the cite of the lesion through a guide catheter having an inside diameter at least slightly greater than the transverse diameter of burr 66. Burr 66 can be rotated as shown by the arrow proximate drive shaft 60 and be engaged with the lesion. Burr 66 can be moved transversely by steering wires 72 and 74 as necessary to remove the plaque.
  • FIG. 3 is a view of yet another embodiment of an atherectomy catheter 110 in accordance with the present invention. Catheter 110 includes an elongate drive shaft 120 having a proximal end and distal end. Drive shaft 120 defines a lumen 121 therethrough. Disposed at the distal end of drive shaft 120 is burr 126 having an abrasive coating 128. Burr 126 includes a generally tubularly shaped member 130 connected to burr 126 at the member's proximal and distal ends. Burr 126 includes lumens 132 in fluid communication with lumen 121 of shaft 120. Lumens 132 lead from lumen 121 to the inside surface of member 130.
  • In use, catheter 110 is advanced to a lesion as described above with respect to the other catheter embodiments. Rather than including a mechanism for transversely shifting a burr however, the tubular member 130 of burr 126 is sufficiently elastic to stretch transversely under the influence of centrifugal force when tip 126 is rotated by shaft 120. Rotation of tip 126, thus will move tubular member 130 from a first position A to a second position B. In second position B, burr 126 can ablate a larger diameter path. While member 130 is moving from position A to position B, fluid may be introduced through lumens 121 and 132 as shown by the arrows into the space created inside member 130.
  • FIG. 4 is a cross-sectional view of yet another embodiment of a catheter 150 in accordance with the present invention. Catheter 150 includes an elongate shaft 156 defining an inflation lumen 157. Disposed proximate the proximal end of shaft 156 is a balloon 166 defining a burr having an abrasive coating 168. Catheter 150 can include a manifold 176 including lumens 178 in fluid communication with lumen 157 and the interior space of balloon 166.
  • In use, balloon 166 is advanced percutaneously to a lesion. At the lesion, balloon 166 is inflated to increase its diameter. Abrasive surface 168 is then advanced into engagement with the plaque. Balloon 166 is then rotated to abrade plaque.
  • FIG. 5 is a partial, cross-sectional view of yet another embodiment of a catheter 210 in accordance with the present invention. Catheter 210 includes an elongate drive shaft 220 having a proximal end and a distal end. A burr 226 is disposed at the distal end of drive shaft 220. Burr 226 includes an abrasive coating 228 and a distal flexible portion or skirt 229 which is free to move generally transversely under the influence of centrifugal force as burr 226 is rotated by shaft 220. The arrows proximate skirt 229 show that the direction of the generally transverse movement of skirt 229 to increase the effective diameter of burr 226. The arrow proximate the distal end of burr 226 shows the rotation of burr 226. While burr 226 is not rotating skirt 229 can be disposed generally parallel to shaft 220 and then elastically stretch to the position shown in FIG. 5 when burr 226 is rotated.
  • FIG. 6 is a side view of yet another alternate embodiment of a catheter 250 in accordance with the present invention. Catheter 250 is shown disposed within a vessel lumen 252. Catheter 250 includes an elongate shaft 256 having a proximal end and a distal end. Catheter 256 includes an outer shaft 258 which defines the drive shaft lumen and two inflation lumens 261. An elongate drive shaft 260 is disposed through the drive shaft lumen. A cup shaped bearing 265 is disposed at the distal end of shaft 256. A burr 266 is connected to the distal end of drive shaft 260. The distal end of burr 266 can include an abrasive coating 268. The proximal end of burr 266 can be nested within bearing 265. Connected to shaft 258 proximate burr 266 are balloons 263. Balloons 263 define a balloon envelope in fluid communication with inflation lumens 261. Additional balloons may be used to increase the positional control of burr 266.
  • Catheter 250 is advanced as described above with respect to the alternate embodiments in accordance with the present invention to perform the atherectomy procedure. Likewise, burr 266 is rotated to abrade plaque. In order to shift burr 266 transversely within lumen 252, balloons 263 may be alternately inflated or deflated to engage the wall of vessel 252 forcing burr 266 transversely in a direction opposite the resultant force of balloons 263 incident the wall of vessel 252.
  • FIG. 7 is a side view of yet another embodiment of a catheter 310 in accordance with the present invention. Catheter 310 includes an elongate shaft 320. Shaft 320 includes a proximal end and a distal end. A burr 326 is disposed eccentrically on shaft 320 proximate the distal end of shaft 320. Burr 326 includes an abrasive coating 328. A counterweight 327 is disposed in burr 326. The counterweight has a weight sufficient to shift the center of mass of burr 326 such that it lies generally on the longitudinal axis of shaft 320. The effect of counterweighting can also be achieved by an asymmetrical shaping of the burr and/or creating voids in the burr to shift the distribution of the burrs weight. This allows burr 326 to be rotated by shaft 320 through a position A and B as shown without whipping the distal end of shaft 322. By eccentrically mounting burr 326 on shaft 320 it can be appreciated by reference to positions A and B that a larger area can be circumscribed by the surface of burr 326 as burr 326 is rotated by shaft 320 than if the burr were rotated about its central axis.
  • FIG. 8 is a view of yet another embodiment of a catheter 350 in accordance with the present invention. Catheter 350 includes an elongate shaft 356. Shaft 356 includes an outer shaft 358 having a proximal end and a distal end and defining a drive shaft lumen therethrough. Shaft 356 also includes a drive shaft 360 disposed through the drive shaft lumen. A cone-shaped bearing 365 is preferably disposed at the distal end of shaft 358. Bearing 356 has a lumen extending longitudinally therethrough, and having a diameter which generally increases distally. A burr 366 is disposed at the distal end of drive shaft 360. Burr 366 can have an abrasive coating (not shown). Burr 366 is preferably formed from a plurality of spring members 380 joined at their respective proximal and distal ends. Members 380 are preferably preformed to assume a transversely expanded shape when unconstrained. The diameter of burr 366 can be reduced by withdrawing burr 366 at least in part into bearing 365. Burr 366 may be withdrawn at least partially into bearing 365 by shifting drive shaft 360 proximally relative to outer shaft 358. Burr 366 can be advanced to the cite of a lesion in the constrained configuration and then expanded, and rotated to abrade plaque.
  • FIG. 9 is an embodiment of yet another catheter 410 in accordance with the present invention. Catheter 410 includes a drive shaft 420 having a proximal end and a distal end. A generally spiral shaped ablation burr 434 is disposed at the distal end of drive shaft 420. Burr 434 can include an abrasive coating (not shown). Upon rotation of drive shaft 420, burr 434 can generally expand or unwind from a position A to a position B under the influence of centrifugal force. Burr 434 as shown has a generally circular cross section. Burr 434 can have a generally rectangular cross section if burr 434 were formed from a ribbon shaped member.
  • FIG. 10 is a view of yet another embodiment of a catheter 450 in accordance with the present invention. Catheter 450 includes an elongate drive shaft 460 having a proximal end and a distal end. A burr 466 is disposed proximate the distal end of shaft 460. Burr 466 can include an abrasive coating 468. A coil 482 can be formed in drive shaft 460 proximate burr 466. Abrasive coating 484 can be deposited on coil 482. Abrasive coating 484 can be deposited in the configuration and plurality of burrs. Coil 482 can be stretched and flattened to be advanced through a guide catheter. As the coil portion of drive shaft 460 is advanced distally from a guide catheter, that portion of drive shaft 460 resumes the coil shape shown in FIG. 10.
  • FIG. 11 is a view of yet another catheter 510 in accordance with the present invention. Catheter 510 includes drive shaft 520 having a proximal end and a distal end. A burr 526 is disposed at the distal end of drive shaft 520. Burr 526 preferably includes an abrasive coating 528. Burr 526 is preferably formed from a generally tubular member 541 which is sealed at its distal end to form an abrasive tip 543. Longitudinal slits 540 are formed in the proximal end of tubular member 541 such that leaves 542 are disposed therebetween. When burr 526 is rotated, leaves 542 will move from a first position A to a second position B under the influence of centrifugal force.
  • FIG. 12 is a view of yet another embodiment of a catheter 550 in accordance with the present invention. Catheter 550 includes an elongate drive shaft 560 having a proximal end and a distal end. Proximate the distal end of drive shaft 560 is a line 586 having a proximal end and a distal end. The proximal end and distal ends of line 586 are connected to drive shaft 560 at a spaced distance less than the length of line 586. Abrasive burrs 588 are deposited along line 586. In FIG. 12, line 586 is in a first position A. In FIG. 13, line 586 is shown in a second position B wherein line 586 is shift transversely under the influence of centrifugal force as drive shaft 560 is rotated.
  • FIG. 14 is a view of yet another catheter 610 in accordance with the present invention. Catheter 610 includes a drive shaft 620 having a proximal end and a distal end. A burr 626 is disposed proximate the distal end of shaft 620. Burr 626 preferably includes an abrasive coating 628. A plurality of bristles extend from burr 626. Disposed at the outside end of each bristle 636 is a burr end 638 which may include an abrasive coating. Bristles 636 can be configured to move from first position A to second position B under the influence of centrifugal force as burr 626 is rotated. Alternately, bristles 633 may be biased to expand between positions A and B upon becoming unconstrained as they are advanced from a guide catheter.
  • FIG. 15 is a side view of yet another catheter 650 in accordance with the present invention. Catheter 650 includes an elongate drive shaft 656 which can include a proximal, helical shaft encased in a polymer. Shaft 656 can also include a distal shaft portion 659 around which is disposed an elastomeric balloon 667. Elastomeric balloon 667 includes a distal portion which is folded over into folds or leaflets 669. The distal end of catheter 650 including the folded region of balloon 667 is preferably coated with an abrasive. FIG. 16 is a view of the distal end of catheter 650 of FIG. 15 and offers an alternate view of folds 669.
  • FIG. 17 is a cross-sectional view of catheter 650 of FIG. 15. The arrow to the right of the figure shows the direction of rotation of balloon 667. In use, as can be seen by comparison of FIG. 17 with FIG. 15, during rotation of balloon 667, the balloon's distal portion including leaves 669 expands from a first position A to a second position B. This is made possible as the space defined between the balloon inner surface and shaft 659 is preferably preloaded with a fluid such as saline prior to advancement to the site of the lesion. The quantity of fluid preloaded into balloon 667 is such that when balloon 667 is not rotated, it will be in a relatively reduced diameter, i.e., position A. Whereas, when balloon 667 is rotated, the fluid with shift by centrifugal force into that distal portion of balloon 667 including leaves 669, expanding balloon 667 into the increased diameter configuration of position B.
  • FIG. 18 shows yet another alternate embodiment of a catheter 710 in accordance with the present invention. Catheter 710 has an elongate shaft 716 having a proximal end a distal end. Shaft 716 includes an outer sheath 718 defining a drive shaft lumen therethrough. Shaft 716 includes an elongate drive shaft 720 disposed through the lumen. Sheath 718 includes a distal bearing surface which preferably defines a lumen having an inside diameter increasing distally. Disposed at the distal end of drive shaft 720 is an expandable burr 726 which preferably has an abrasive coating (not shown). Burr 726 can be formed from a plurality of spring member similar to the spring members 380 of catheter 350 shown in FIG. 8. For clarity, in FIG. 18, only two spring members 740 are shown.
  • An elastomeric shell is disposed within burr 726 to avoid an increase in hemolysis or platelet aggregation. Shell 742 preferably encloses a main body 743 and unidirectional ratchet 744 including reverse positive stop 746. A threaded member 800 is threaded into a sleeve 745. Threaded member 800 is fixably connected at its distal end to stop 746 and fixably connected at its proximal end to forward motion positive stop 747. Threaded member 800 is also fixably connected to drive shaft 720. Spring members 740 are connected at their proximal ends to sleeve 745 and fixably held in position by collar 748. The distal ends of spring members 740 are fixably connected to the distal end of main body 743. Main body 743 is connected at its proximal end about a pin 804 to ratchet 744. Ratchet 744 includes teeth 802 and the main body portion includes teeth 806. Teeth 802 and 806 are shown in FIG. 8 meshed along angled surfaces 808 and longitudinally extended surfaces 810.
  • In use, ratchet 744 and main body 743 can be used to control the transverse diameter D of burr 726. For example, a burr advancable through an 8F guide catheter could be expanded between 2.0 mm and 3.5 mm in diameter, at 0.25 mm intervals or steps. The ability to control the diameter of burrs 726 at such steps can be considered indexing. To increase the diameter of burr 726 by indexing, drive shaft 720 can be rotated such that teeth 802 and 806 engage each other along surfaces 808. Since surfaces 808 are inclined, teeth 806 will tend to rise out from between 802 momentarily increasing the length of burr 726. As drive shaft 720 continues to rotate, the teeth will index and reengage the adjacent teeth. As ratchet 744 was rotated, stop 746 will have moved toward stay 745 shortening the distance between distal end 749 of burr 726 and sleeve 745, thus increasing the diameter of burr 726. This assumes that the spring members 740 bias burr 726 toward its largest diameter. This procedure can be repeated to step wise increase the diameter of burr 726. It can be appreciated that burr 726 can be kept from rotating during indexing by engagement with sheath 718 or the vessel or vessel lesion. When drive shaft 720 is rotating in the opposite direction to engage teeth 802 and 806 along longitudinally extending surface 810, burr 726 can be rotated to ablate a lesion.
  • The diameter of burr 726 can be reduced by merely withdrawing it at least in part into sheath 718. Burr 726 can be withdrawn into sheath 718 sufficiently such that teeth 802 and 806 will be unmeshed. When teeth 802 and 806 are unmeshed, drive shaft 720 can be rotated to advance stop 747 to sleeve 745. At that point, burr 726 is reset to index from its smallest indexing diameter to its largest as described above.
  • FIG. 19 is a cross-sectional view of yet another embodiment of a catheter 750 in accordance with the present invention. Catheter 750 includes an elongate drive shaft 760 having a proximal end and a distal end. Drive shaft 760 can be, for example, formed from a helical member surrounded by a polymer sheath. A burr 766 is disposed at the distal end of shaft 760 connected to burr 766 is a loosely spiraled ribbon member 767 which has a reduced length and width as it spirals outwardly from shaft 760. Abrasive coating 768 can also be applied to ribbon member 767. Like the spiraling member 434 of catheter 410 of FIG. 9, ribbon member 767 will tend to unwind and expand transversely when rotated in one direction.
  • Numerous advantages of the invention covered by this document have been set forth in the foregoing description. It will be understood, however, that this disclosure is, in many respects, only illustrative. Changes may be made in details, particularly in matters of shape, size, and arrangement of parts without exceeding the scope of the invention. The inventions's scope is, of course, defined in the language in which the appended claims are expressed.

Claims (11)

1-22. (canceled)
23. A catheter assembly, comprising:
an elongate drive shaft having a proximal end and a distal end; and
an ablation burr eccentrically connected to the drive shaft at the distal end thereof.
24. The catheter assembly in accordance with claim 23, further comprising a counter weight connected to the burr.
25. The catheter assembly in accordance with claim 23, wherein the burr includes an abrasive surface.
26-31. (canceled)
32. A method of removing lesion material from a patient's blood vessel, comprising the steps of:
routing a catheter through a blood vessel having a central axis, the catheter including an elongate shaft having proximal and distal ends and defining a drive shaft lumen, a driveshaft having proximal and distal ends disposed in the drive shaft lumen, an ablation burr disposed on the distal end of the driveshaft for rotation therewith, and first and second inflation balloons disposed eccentrically on the shaft proximate the burr, wherein inflation of the first balloon urges the ablation burr in a first direction transverse of the central axis of the blood vessel and inflation of the second balloon urges the ablation burr in a second direction transverse of the central axis of the blood vessel;
inflating the first or second balloon to urge the ablation burr in a direction transverse of the central axis of the blood vessel and into contact with lesion material deposited on a sidewall of the blood vessel; and
rotating the burr.
33. The method of claim 32, further comprising:
deflating the first or second balloon; and
inflating the other of the first or second balloon to urge the ablation burr in another direction transverse of the central axis of the blood vessel.
34. The method of claim 32, further comprising supporting a proximal end of the ablation burr.
35. The method of claim 32, wherein the first and second balloons are disposed on opposite sides of the shaft.
36. The method of claim 32, wherein the catheter further includes a bearing positioned at the distal end of the shaft, the bearing defining a bearing surface that is capable of supporting a proximal end of the ablation burr.
37. The method of claim 36, wherein the bearing is cup shaped.
US11/070,446 1998-03-05 2005-03-01 Ablation burr Abandoned US20050149084A1 (en)

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US09/670,416 US6596005B1 (en) 1998-03-05 2000-09-26 Steerable ablation burr
US10/448,476 US20030199889A1 (en) 1998-03-05 2003-05-29 Ablation burr
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US10/448,476 Abandoned US20030199889A1 (en) 1998-03-05 2003-05-29 Ablation burr
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Cited By (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090018565A1 (en) * 2006-06-30 2009-01-15 Artheromed, Inc. Atherectomy devices, systems, and methods
US20090221955A1 (en) * 2006-08-08 2009-09-03 Bacoustics, Llc Ablative ultrasonic-cryogenic methods
US20090234378A1 (en) * 2007-10-22 2009-09-17 Atheromed, Inc. Atherectomy devices and methods
WO2009146248A1 (en) * 2008-05-30 2009-12-03 Cardiovascular Systems, Inc. Eccentric abrading and cutting head for high-speed rotational atherectomy devices
US20090299392A1 (en) * 2008-05-30 2009-12-03 Cardiovascular Systems, Inc. Eccentric abrading element for high-speed rotational atherectomy devices
US20090306689A1 (en) * 2008-06-05 2009-12-10 Cardiovascular Systems, Inc. Bidirectional expandable head for rotational atherectomy device
US20100198239A1 (en) * 2009-02-02 2010-08-05 Cardiovascular Systems, Inc. Multi-material abrading head for atherectomy devices having laterally displaced center of mass
US20100292720A1 (en) * 2009-05-12 2010-11-18 Cardiovascular Systems, Inc. Rotational atherectomy device and method to improve abrading efficiency
EP2303152A1 (en) * 2008-06-05 2011-04-06 Cardiovascular Systems, Inc. Abrasive nose cone with expandable cutting and sanding region for rotational atherectomy device
US7981128B2 (en) 2006-06-30 2011-07-19 Atheromed, Inc. Atherectomy devices and methods
US20110202079A1 (en) * 2010-02-18 2011-08-18 Cardiovascular Systems, Inc. Therapeutic agent delivery system, device and method for localized application of therapeutic substances to a biological conduit
US8007506B2 (en) 2006-06-30 2011-08-30 Atheromed, Inc. Atherectomy devices and methods
US8236016B2 (en) 2007-10-22 2012-08-07 Atheromed, Inc. Atherectomy devices and methods
US8361094B2 (en) 2006-06-30 2013-01-29 Atheromed, Inc. Atherectomy devices and methods
WO2013134285A1 (en) * 2012-03-05 2013-09-12 Petrucci Gary Treating occlusions within body vessels
US8597313B2 (en) 2007-06-11 2013-12-03 Cardiovascular Systems, Inc. Eccentric abrading head for high-speed rotational atherectomy devices
US8795306B2 (en) 2011-10-13 2014-08-05 Atheromed, Inc. Atherectomy apparatus, systems and methods
US9055966B2 (en) 2008-05-30 2015-06-16 Cardiovascular Systems, Inc. Eccentric abrading and cutting head for high-speed rotational atherectomy devices
US9308016B2 (en) 2006-06-30 2016-04-12 Atheromed, Inc. Devices, systems, and methods for performing atherectomy including delivery of a bioactive material
US9314263B2 (en) 2006-06-30 2016-04-19 Atheromed, Inc. Atherectomy devices, systems, and methods
USD766433S1 (en) 2013-11-04 2016-09-13 Cardiovascular Systems, Inc. Eccentric crown
US9468457B2 (en) 2013-09-30 2016-10-18 Cardiovascular Systems, Inc. Atherectomy device with eccentric crown
US9492192B2 (en) 2006-06-30 2016-11-15 Atheromed, Inc. Atherectomy devices, systems, and methods
US9675376B2 (en) 2006-06-30 2017-06-13 Atheromed, Inc. Atherectomy devices and methods
US9750525B2 (en) 2013-03-14 2017-09-05 Cardiovascular Systems, Inc. Devices, systems and methods for an oscillating crown drive for rotational atherectomy
US9936970B2 (en) 2013-03-14 2018-04-10 Cardiovascular Systems, Inc. Devices, systems and methods for an oscillating crown drive for rotational atherectomy
US10271869B2 (en) 2014-03-01 2019-04-30 Rex Medical, L.P. Atherectomy device
US10307175B2 (en) 2016-03-26 2019-06-04 Rex Medical, L.P Atherectomy device
US10433868B2 (en) 2014-12-27 2019-10-08 Rex Medical, L.P. Artherectomy device
US10463389B2 (en) 2014-12-27 2019-11-05 Rex Medical, L.P. Atherectomy device
US10869689B2 (en) 2017-05-03 2020-12-22 Medtronic Vascular, Inc. Tissue-removing catheter
US11207096B2 (en) 2006-06-30 2021-12-28 Atheromed, Inc. Devices systems and methods for cutting and removing occlusive material from a body lumen
US11253292B2 (en) 2015-09-13 2022-02-22 Rex Medical, L.P. Atherectomy device
US11304723B1 (en) 2020-12-17 2022-04-19 Avantec Vascular Corporation Atherectomy devices that are self-driving with controlled deflection
US11690645B2 (en) 2017-05-03 2023-07-04 Medtronic Vascular, Inc. Tissue-removing catheter
US11819236B2 (en) 2019-05-17 2023-11-21 Medtronic Vascular, Inc. Tissue-removing catheter

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6146395A (en) * 1998-03-05 2000-11-14 Scimed Life Systems, Inc. Ablation burr
US6929633B2 (en) 2000-01-25 2005-08-16 Bacchus Vascular, Inc. Apparatus and methods for clot dissolution
US6663613B1 (en) 2000-01-25 2003-12-16 Bacchus Vascular, Inc. System and methods for clot dissolution
US6579299B2 (en) * 2000-01-31 2003-06-17 Rex Medical, L.P. Atherectomy device
US6572630B1 (en) * 2000-01-31 2003-06-03 Rex Medical, L.P Atherectomy device
US6402745B1 (en) * 2000-02-23 2002-06-11 Peter J. Wilk Intravenous whip electrode for vein ablation
US6579298B1 (en) * 2000-02-29 2003-06-17 Scimed Life Systems, Inc. Method and apparatus for treating vein graft lesions
US6565588B1 (en) 2000-04-05 2003-05-20 Pathway Medical Technologies, Inc. Intralumenal material removal using an expandable cutting device
AU2001253173B2 (en) 2000-04-05 2005-05-12 Boston Scientific Limited Intralumenal material removal systems and methods
US7862541B2 (en) * 2000-05-22 2011-01-04 Abbott Laboratories Vascular Enterprises Limited Catheter having a soft distal tip
EP1169970A1 (en) * 2000-07-04 2002-01-09 Transgene S.A. Device for the administration of a composition in a conduit of a human or animal body
NL1016653C2 (en) * 2000-11-20 2002-05-22 Hendrik Glastra Surgical method for removing obstructions in blood vessel, comprises fixing distal end of catheter in relation to vessel wall prior to carrying out removal work
US6569177B1 (en) 2001-01-19 2003-05-27 Scimed Life Systems, Inc. Ablation atherectomy burr
US6491660B2 (en) * 2001-01-23 2002-12-10 Scimed Life Systems, Inc. Frontal infusion system for intravenous burrs
US6800083B2 (en) 2001-04-09 2004-10-05 Scimed Life Systems, Inc. Compressible atherectomy burr
US6632230B2 (en) * 2001-04-12 2003-10-14 Scimed Life Systems, Inc. Ablation system with catheter clearing abrasive
US6500186B2 (en) 2001-04-17 2002-12-31 Scimed Life Systems, Inc. In-stent ablative tool
US8014849B2 (en) 2003-11-21 2011-09-06 Stryker Corporation Rotational markers
US8382739B2 (en) 2003-12-02 2013-02-26 Boston Scientific Scimed, Inc. Composite medical device and method of forming
US20050209610A1 (en) * 2004-03-03 2005-09-22 Scimed Life Systems, Inc. Radially adjustable tissue removal device
US7976557B2 (en) * 2004-06-23 2011-07-12 Boston Scientific Scimed, Inc. Cutting balloon and process
ATE409063T1 (en) * 2005-01-21 2008-10-15 Abbott Lab Vascular Entpr Ltd BALLOON CATHETER WITH A SOFT TIP
WO2006084256A2 (en) * 2005-02-02 2006-08-10 Peacock James C Total vascular occlusion treatment system and method
GB2426458A (en) 2005-05-26 2006-11-29 Leonid Shturman Atherectomy device
GB2426456B (en) * 2005-05-26 2010-10-27 Leonid Shturman Rotational device with eccentric abrasive element and method of use
US20070162062A1 (en) * 2005-12-08 2007-07-12 Norton Britt K Reciprocating apparatus and methods for removal of intervertebral disc tissues
US8092470B2 (en) * 2006-06-08 2012-01-10 Olympus Medical Systems Corp. Calculus crushing apparatus and medical procedure using endoscope
US20070299435A1 (en) * 2006-06-23 2007-12-27 Crowe John E Apparatus and method for ablating tissue
US8109957B2 (en) * 2006-06-30 2012-02-07 Depuy Spine, Inc. Disc nucleus removal devices and methods
GB0613981D0 (en) 2006-07-13 2006-08-23 Shturman Leonid
GB0623366D0 (en) 2006-11-23 2007-01-03 Shturman Leonid Rotational atherectomy device with fluid inflatable support elements and distal protection capability
GB0613979D0 (en) 2006-07-13 2006-08-23 Shturman Leonid Rotational atherectomy device with solid support elements supported by fluid bearings
GB0613982D0 (en) 2006-07-13 2006-08-23 Shturman Leonid Rotational atherectomy device with fluid inflatable support elements and two torque transmitting coils
GB0613980D0 (en) 2006-07-13 2006-08-23 Shturman Leonid Rotational Atherectomy Device with Fluid Inflatable Elements supported by Fluid Bearings
US20080269774A1 (en) 2006-10-26 2008-10-30 Chestnut Medical Technologies, Inc. Intracorporeal Grasping Device
US20080275490A1 (en) * 2007-05-01 2008-11-06 Fleming James A Medical filter with partial baskets
US9125683B2 (en) 2007-06-26 2015-09-08 Roxwood Medical Inc. Method and apparatus for placing a catheter within a vasculature
US9126020B2 (en) 2007-06-26 2015-09-08 Roxwood Medical, Inc. Catheter apparatus with telescoping lumen catheters and its use in methods for treating vasculatures
WO2009003113A1 (en) 2007-06-26 2008-12-31 Unique Catheter Designs, Llc Catheter apparatus and methods for treating vasculatures
US9358037B2 (en) 2007-06-26 2016-06-07 Roxwood Medical, Inc. Method and apparatus for centering a microcatheter within a vasculature
US8475478B2 (en) * 2007-07-05 2013-07-02 Cardiovascular Systems, Inc. Cleaning apparatus and method for high-speed rotational atherectomy devices
US8348965B2 (en) * 2007-10-23 2013-01-08 Cardiovascular Systems, Inc. Rotational atherectomy device with counterweighting
GB0722990D0 (en) 2007-11-23 2008-01-02 Shturman Leonid Rotational atherectomy system with enhanced distal protection capability and method of use
US8551128B2 (en) * 2007-12-06 2013-10-08 Cardiovascular Systems, Inc. Rotational atherectomy device with pre-curved drive shaft
US8162964B2 (en) 2008-06-05 2012-04-24 Cardiovascular Systems, Inc. Split flexible tube biasing and directional atherectomy device and method
US8628550B2 (en) * 2009-02-19 2014-01-14 Cardiovascular Systems, Inc. Rotational atherectomy segmented abrading head and method to improve abrading efficiency
GB0905748D0 (en) 2009-04-03 2009-05-20 Shturman Leonid Rotational atherectomy device with eccentric abrasive element and method of use
GB0905751D0 (en) 2009-04-03 2009-05-20 Shturman Leonid Rotational atherectomy device with distal embolic protection and method of use
US9907567B2 (en) * 2010-05-04 2018-03-06 Samuel Shiber Mechanical — pharmaceutical system for opening obstructed bodily vessels
WO2012003375A1 (en) * 2010-06-30 2012-01-05 Smith & Nephew, Inc. Resection instrument
WO2012003371A1 (en) 2010-06-30 2012-01-05 Smith & Nephew, Inc. Bone and tissue marker
US8998936B2 (en) 2011-06-30 2015-04-07 The Spectranetics Corporation Reentry catheter and method thereof
US9814862B2 (en) 2011-06-30 2017-11-14 The Spectranetics Corporation Reentry catheter and method thereof
US8956376B2 (en) 2011-06-30 2015-02-17 The Spectranetics Corporation Reentry catheter and method thereof
US9456842B2 (en) * 2012-07-13 2016-10-04 Boston Scientific Scimed, Inc. Wire-guided recanalization system
US9289230B2 (en) 2012-09-17 2016-03-22 Cardiovascular Systems, Inc. Rotational atherectomy device with a system of eccentric abrading heads
WO2014066412A1 (en) 2012-10-22 2014-05-01 Roxwood Medical, Inc. Method and apparatus for centering a microcatheter within a vasculature
JP6087020B2 (en) * 2013-03-12 2017-03-01 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Atherectomy device
US20150080795A1 (en) * 2013-07-26 2015-03-19 Cardiovascular Systems, Inc. Devices, systems and methods for performing atherectomy and subsequent balloon angioplasty without exchanging devices
US9788853B2 (en) 2014-01-15 2017-10-17 Cardio Flow, Inc. Atherectomy devices and methods
CN106456208B (en) 2014-03-12 2020-04-03 波士顿科学有限公司 Injection lubrication atherectomy catheter
WO2016089847A1 (en) 2014-12-04 2016-06-09 Boston Scientific Scimed, Inc. Rotatable medical device
WO2016138424A1 (en) * 2015-02-28 2016-09-01 Transmed7, Llc Devices and methods for percutaneous transluminal angioplasty and atherectomy intervention procedures
US10080571B2 (en) 2015-03-06 2018-09-25 Warsaw Orthopedic, Inc. Surgical instrument and method
CN108289992B (en) 2015-08-14 2022-03-01 美酷有限公司 Infusion fluid warmer including printed circuit board heating element
WO2017053798A1 (en) 2015-09-25 2017-03-30 Mark Taber Guide wires, catheters, and guide wire catheter systems and methods
WO2017164119A1 (en) 2016-03-23 2017-09-28 テルモ株式会社 Medical device and treatment method
US10441312B2 (en) 2017-02-23 2019-10-15 Cardio Flow, Inc. Atherectomy devices and methods
WO2019118522A1 (en) 2017-12-12 2019-06-20 Boston Scientific Scimed, Inc. Rotational medical device
US10463390B1 (en) 2018-05-24 2019-11-05 Cardio Flow, Inc. Atherectomy devices and methods
US11147582B2 (en) 2018-06-14 2021-10-19 Cardio Flow, Inc. Atherectomy devices and methods
US11272954B2 (en) 2018-08-07 2022-03-15 Cardio Flow, Inc. Atherectomy devices and methods
US11730509B2 (en) 2018-10-08 2023-08-22 Cardiovascular Systems, Inc. Devices and methods for generating orbital motion in drive shafts for rotational medical devices
WO2022032038A1 (en) * 2020-08-05 2022-02-10 Fojtik Shawn P Medical aspiration devices and methods

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5058476A (en) * 1988-07-29 1991-10-22 Shopsmith, Inc. Scroll saw
US5308354A (en) * 1991-07-15 1994-05-03 Zacca Nadim M Atherectomy and angioplasty method and apparatus
US5628761A (en) * 1994-07-08 1997-05-13 Rizik; David G. Guide wire passage creation device
US5667490A (en) * 1992-10-07 1997-09-16 Scimed Life Systems, Inc. Ablation device drive assembly including catheter connector
US6126667A (en) * 1999-10-01 2000-10-03 Scimed Life Systems, Inc. Articulated ablation device
US6146395A (en) * 1998-03-05 2000-11-14 Scimed Life Systems, Inc. Ablation burr
US6258109B1 (en) * 1997-03-06 2001-07-10 Scimed Life Systems, Inc. Guidewire bearing to prevent darting
US6416526B1 (en) * 1998-03-05 2002-07-09 Scimed Life Systems, Inc. Expandable atherectomy burr
US6494890B1 (en) * 1997-08-14 2002-12-17 Shturman Cardiology Systems, Inc. Eccentric rotational atherectomy device

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3058473A (en) * 1959-11-27 1962-10-16 Alfred E Whitchead Remotely directing catheters and tools
US3320957A (en) * 1964-05-21 1967-05-23 Sokolik Edward Surgical instrument
US3996938A (en) * 1975-07-10 1976-12-14 Clark Iii William T Expanding mesh catheter
US4273128A (en) * 1980-01-14 1981-06-16 Lary Banning G Coronary cutting and dilating instrument
US4445509A (en) * 1982-02-04 1984-05-01 Auth David C Method and apparatus for removal of enclosed abnormal deposits
US4627436A (en) * 1984-03-01 1986-12-09 Innoventions Biomedical Inc. Angioplasty catheter and method for use thereof
US4685458A (en) 1984-03-01 1987-08-11 Vaser, Inc. Angioplasty catheter and method for use thereof
US4886490A (en) * 1984-05-14 1989-12-12 Surgical Systems & Instruments, Inc. Atherectomy catheter system and method of using the same
US4926858A (en) * 1984-05-30 1990-05-22 Devices For Vascular Intervention, Inc. Atherectomy device for severe occlusions
US4944740A (en) * 1984-09-18 1990-07-31 Medtronic Versaflex, Inc. Outer exchange catheter system
US4650466A (en) * 1985-11-01 1987-03-17 Angiobrade Partners Angioplasty device
US4658458A (en) * 1986-04-16 1987-04-21 Shop-Vac Corporation Rotary brush sweeper with mechanism for brush height adjustment
US5071406A (en) * 1987-05-06 1991-12-10 Jang G David Limacon geometry balloon angioplasty catheter systems
US4850957A (en) * 1988-01-11 1989-07-25 American Biomed, Inc. Atherectomy catheter
US4924863A (en) * 1988-05-04 1990-05-15 Mmtc, Inc. Angioplastic method for removing plaque from a vas
US5372587A (en) * 1989-01-09 1994-12-13 Pilot Cariovascular Systems, Inc. Steerable medical device
US4986807A (en) * 1989-01-23 1991-01-22 Interventional Technologies, Inc. Atherectomy cutter with radially projecting blade
US4950277A (en) * 1989-01-23 1990-08-21 Interventional Technologies, Inc. Atherectomy cutting device with eccentric wire and method
US5087265A (en) * 1989-02-17 1992-02-11 American Biomed, Inc. Distal atherectomy catheter
US5041124A (en) * 1989-07-14 1991-08-20 Kensey Nash Corporation Apparatus and method for sclerosing of body tissue
US5071424A (en) * 1989-08-18 1991-12-10 Evi Corporation Catheter atherotome
US5034001A (en) * 1989-09-08 1991-07-23 Advanced Cardiovascular Systems, Inc. Method of repairing a damaged blood vessel with an expandable cage catheter
JPH03128028A (en) * 1989-10-13 1991-05-31 Machida Seisakusho:Kk Angle for curving operation device
US5009659A (en) * 1989-10-30 1991-04-23 Schneider (Usa) Inc. Fiber tip atherectomy catheter
US5030201A (en) * 1989-11-24 1991-07-09 Aubrey Palestrant Expandable atherectomy catheter device
US5074871A (en) * 1989-12-07 1991-12-24 Evi Corporation Catheter atherotome
US5222966A (en) * 1990-02-28 1993-06-29 Devices For Vascular Intervention, Inc. Balloon connection and inflation lumen for atherectomy catheter
US6277136B1 (en) * 1990-03-02 2001-08-21 General Surgical Innovations, Inc. Method for developing an anatomic space
US5342304A (en) * 1990-03-16 1994-08-30 Advanced Cardiovascular Systems, Inc. Inflation device for dilatation catheters
US5100424A (en) * 1990-05-21 1992-03-31 Cardiovascular Imaging Systems, Inc. Intravascular catheter having combined imaging abrasion head
US5207648A (en) * 1990-12-14 1993-05-04 The Kendall Company Multilumen catheter
US5167239A (en) * 1991-05-30 1992-12-01 Endomedix Corporation Anchorable guidewire
CA2126096C (en) * 1992-01-13 1998-04-28 Rick L. Shockey Surgical cutting tool
SE470177B (en) * 1992-03-23 1993-11-29 Radi Medical Systems Device for punching in hard tissue and puncture needle
US5250060A (en) * 1992-06-26 1993-10-05 Carbo Paul L Angioplasty apparatus
US5356418A (en) * 1992-10-28 1994-10-18 Shturman Cardiology Systems, Inc. Apparatus and method for rotational atherectomy
US5312427A (en) * 1992-10-16 1994-05-17 Shturman Cardiology Systems, Inc. Device and method for directional rotational atherectomy
US5360432A (en) * 1992-10-16 1994-11-01 Shturman Cardiology Systems, Inc. Abrasive drive shaft device for directional rotational atherectomy
US5643297A (en) * 1992-11-09 1997-07-01 Endovascular Instruments, Inc. Intra-artery obstruction clearing apparatus and methods
US5836868A (en) * 1992-11-13 1998-11-17 Scimed Life Systems, Inc. Expandable intravascular occlusion material removal devices and methods of use
CA2109980A1 (en) * 1992-12-01 1994-06-02 Mir A. Imran Steerable catheter with adjustable bend location and/or radius and method
US5304199A (en) * 1993-01-04 1994-04-19 Gene E. Myers Enterprises, Inc. Apparatus for arterial total occlusion plaque separation
US5417703A (en) * 1993-07-13 1995-05-23 Scimed Life Systems, Inc. Thrombectomy devices and methods of using same
US5462529A (en) * 1993-09-29 1995-10-31 Technology Development Center Adjustable treatment chamber catheter
US5873103A (en) * 1994-02-25 1999-02-16 Kodak Limited Data storage management for network interconnected processors using transferrable placeholders
CA2157697C (en) * 1995-01-10 2007-03-13 Banning Gray Lary Vascular incisor/dilator
US5554163A (en) * 1995-04-27 1996-09-10 Shturman Cardiology Systems, Inc. Atherectomy device
US5749883A (en) * 1995-08-30 1998-05-12 Halpern; David Marcos Medical instrument
US5681336A (en) * 1995-09-07 1997-10-28 Boston Scientific Corporation Therapeutic device for treating vien graft lesions
US5766192A (en) * 1995-10-20 1998-06-16 Zacca; Nadim M. Atherectomy, angioplasty and stent method and apparatus
US5897566A (en) * 1996-07-15 1999-04-27 Shturman Cardiology Systems, Inc. Rotational atherectomy device
US5779721A (en) * 1996-07-26 1998-07-14 Kensey Nash Corporation System and method of use for revascularizing stenotic bypass grafts and other blood vessels
US5882329A (en) * 1997-02-12 1999-03-16 Prolifix Medical, Inc. Apparatus and method for removing stenotic material from stents
US5843103A (en) * 1997-03-06 1998-12-01 Scimed Life Systems, Inc. Shaped wire rotational atherectomy device
US5895400A (en) * 1997-06-27 1999-04-20 Abela; George S. Catheter with bristles
US6132444A (en) * 1997-08-14 2000-10-17 Shturman Cardiology Systems, Inc. Eccentric drive shaft for atherectomy device and method for manufacture
US5976165A (en) * 1997-12-10 1999-11-02 Scimed Life Systems, Inc. Rotational ablation device having replaceable screw-on burrs

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5058476A (en) * 1988-07-29 1991-10-22 Shopsmith, Inc. Scroll saw
US5308354A (en) * 1991-07-15 1994-05-03 Zacca Nadim M Atherectomy and angioplasty method and apparatus
US5667490A (en) * 1992-10-07 1997-09-16 Scimed Life Systems, Inc. Ablation device drive assembly including catheter connector
US5916227A (en) * 1992-10-07 1999-06-29 Scimed Life Systems, Inc. Ablation devices and methods of use
US6080171A (en) * 1992-10-07 2000-06-27 Scimed Life Systems, Inc. Ablation devices and methods of use
US5628761A (en) * 1994-07-08 1997-05-13 Rizik; David G. Guide wire passage creation device
US6258109B1 (en) * 1997-03-06 2001-07-10 Scimed Life Systems, Inc. Guidewire bearing to prevent darting
US6494890B1 (en) * 1997-08-14 2002-12-17 Shturman Cardiology Systems, Inc. Eccentric rotational atherectomy device
US6416526B1 (en) * 1998-03-05 2002-07-09 Scimed Life Systems, Inc. Expandable atherectomy burr
US6146395A (en) * 1998-03-05 2000-11-14 Scimed Life Systems, Inc. Ablation burr
US20030199889A1 (en) * 1998-03-05 2003-10-23 Scimed Life Systems, Inc. Ablation burr
US6685718B1 (en) * 1998-03-05 2004-02-03 Scimed Life Systems, Inc. Expandable ablation burr
US20040158270A1 (en) * 1998-03-05 2004-08-12 Scimed Life Systems, Inc. Expandable ablation burr
US6126667A (en) * 1999-10-01 2000-10-03 Scimed Life Systems, Inc. Articulated ablation device

Cited By (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7981128B2 (en) 2006-06-30 2011-07-19 Atheromed, Inc. Atherectomy devices and methods
US20090018565A1 (en) * 2006-06-30 2009-01-15 Artheromed, Inc. Atherectomy devices, systems, and methods
US11207096B2 (en) 2006-06-30 2021-12-28 Atheromed, Inc. Devices systems and methods for cutting and removing occlusive material from a body lumen
US10226275B2 (en) 2006-06-30 2019-03-12 Atheromed, Inc. Devices, systems, and methods for debulking restenosis of a blood vessel
US10154854B2 (en) 2006-06-30 2018-12-18 Atheromed, Inc. Atherectomy devices and methods
US10154853B2 (en) 2006-06-30 2018-12-18 Atheromed, Inc. Devices, systems, and methods for cutting and removing occlusive material from a body lumen
US9675376B2 (en) 2006-06-30 2017-06-13 Atheromed, Inc. Atherectomy devices and methods
US9492192B2 (en) 2006-06-30 2016-11-15 Atheromed, Inc. Atherectomy devices, systems, and methods
US8361094B2 (en) 2006-06-30 2013-01-29 Atheromed, Inc. Atherectomy devices and methods
US8628549B2 (en) 2006-06-30 2014-01-14 Atheromed, Inc. Atherectomy devices, systems, and methods
US9668767B2 (en) 2006-06-30 2017-06-06 Atheromed, Inc. Atherectomy devices and methods
US9314263B2 (en) 2006-06-30 2016-04-19 Atheromed, Inc. Atherectomy devices, systems, and methods
US9308016B2 (en) 2006-06-30 2016-04-12 Atheromed, Inc. Devices, systems, and methods for performing atherectomy including delivery of a bioactive material
US8007506B2 (en) 2006-06-30 2011-08-30 Atheromed, Inc. Atherectomy devices and methods
US9492193B2 (en) 2006-06-30 2016-11-15 Atheromed, Inc. Devices, systems, and methods for cutting and removing occlusive material from a body lumen
US8920448B2 (en) 2006-06-30 2014-12-30 Atheromed, Inc. Atherectomy devices and methods
US8888801B2 (en) 2006-06-30 2014-11-18 Atheromed, Inc. Atherectomy devices and methods
US20090221955A1 (en) * 2006-08-08 2009-09-03 Bacoustics, Llc Ablative ultrasonic-cryogenic methods
CN105455881A (en) * 2007-06-11 2016-04-06 心血管系统股份有限公司 Eccentric abrading head for high-speed rotational atherectomy devices
US8597313B2 (en) 2007-06-11 2013-12-03 Cardiovascular Systems, Inc. Eccentric abrading head for high-speed rotational atherectomy devices
US8236016B2 (en) 2007-10-22 2012-08-07 Atheromed, Inc. Atherectomy devices and methods
US20090234378A1 (en) * 2007-10-22 2009-09-17 Atheromed, Inc. Atherectomy devices and methods
US9333007B2 (en) 2007-10-22 2016-05-10 Atheromed, Inc. Atherectomy devices and methods
US8337516B2 (en) 2007-10-22 2012-12-25 Atheromed, Inc. Atherectomy devices and methods
US8070762B2 (en) 2007-10-22 2011-12-06 Atheromed Inc. Atherectomy devices and methods
US8647355B2 (en) 2007-10-22 2014-02-11 Atheromed, Inc. Atherectomy devices and methods
US9198679B2 (en) 2007-10-22 2015-12-01 Atheromed, Inc. Atherectomy devices and methods
US9095371B2 (en) 2007-10-22 2015-08-04 Atheromed, Inc. Atherectomy devices and methods
US8702735B2 (en) 2008-05-30 2014-04-22 Cardiovascular Systems, Inc. Eccentric abrading element for high-speed rotational atherectomy devices
US20090299391A1 (en) * 2008-05-30 2009-12-03 Cardiovascular Systems, Inc. Eccentric abrading and cutting head for high-speed rotational atherectomy devices
US20090299392A1 (en) * 2008-05-30 2009-12-03 Cardiovascular Systems, Inc. Eccentric abrading element for high-speed rotational atherectomy devices
WO2009146248A1 (en) * 2008-05-30 2009-12-03 Cardiovascular Systems, Inc. Eccentric abrading and cutting head for high-speed rotational atherectomy devices
US9055966B2 (en) 2008-05-30 2015-06-16 Cardiovascular Systems, Inc. Eccentric abrading and cutting head for high-speed rotational atherectomy devices
US8758377B2 (en) * 2008-05-30 2014-06-24 Cardiovascular Systems, Inc. Eccentric abrading and cutting head for high-speed rotational atherectomy devices
JP2011522599A (en) * 2008-06-05 2011-08-04 カーディオバスキュラー システムズ, インコーポレイテッド Polishing nose cone with expandable cutting and polishing area for rotary atherectomy device
US9186170B2 (en) * 2008-06-05 2015-11-17 Cardiovascular Systems, Inc. Bidirectional expandable head for rotational atherectomy device
US20090306689A1 (en) * 2008-06-05 2009-12-10 Cardiovascular Systems, Inc. Bidirectional expandable head for rotational atherectomy device
EP2303152A4 (en) * 2008-06-05 2011-12-07 Cardivascular Systems Abrasive nose cone with expandable cutting and sanding region for rotational atherectomy device
EP2303152A1 (en) * 2008-06-05 2011-04-06 Cardiovascular Systems, Inc. Abrasive nose cone with expandable cutting and sanding region for rotational atherectomy device
US8795303B2 (en) 2009-02-02 2014-08-05 Cardiovascular Systems, Inc. Multi-material abrading head for atherectomy devices having laterally displaced center of mass
US20100198239A1 (en) * 2009-02-02 2010-08-05 Cardiovascular Systems, Inc. Multi-material abrading head for atherectomy devices having laterally displaced center of mass
US20100292720A1 (en) * 2009-05-12 2010-11-18 Cardiovascular Systems, Inc. Rotational atherectomy device and method to improve abrading efficiency
US8632557B2 (en) * 2009-05-12 2014-01-21 Cardiovascular Systems, Inc. Rotational atherectomy device and method to improve abrading efficiency
CN102438535A (en) * 2009-05-12 2012-05-02 心血管系统股份有限公司 Rotational atherectomy device and method to improve abrading efficiency
US8551130B2 (en) * 2010-02-18 2013-10-08 Cardiovascular Systems, Inc. Therapeutic agent delivery system, device and method for localized application of therapeutic substances to a biological conduit
US20110202079A1 (en) * 2010-02-18 2011-08-18 Cardiovascular Systems, Inc. Therapeutic agent delivery system, device and method for localized application of therapeutic substances to a biological conduit
US11259835B2 (en) 2011-10-13 2022-03-01 Atheromed, Inc. Atherectomy apparatus systems and methods
US9345511B2 (en) 2011-10-13 2016-05-24 Atheromed, Inc. Atherectomy apparatus, systems and methods
US10226277B2 (en) 2011-10-13 2019-03-12 Atheromed, Inc. Atherectomy apparatus, systems, and methods
US8795306B2 (en) 2011-10-13 2014-08-05 Atheromed, Inc. Atherectomy apparatus, systems and methods
WO2013134285A1 (en) * 2012-03-05 2013-09-12 Petrucci Gary Treating occlusions within body vessels
US9750525B2 (en) 2013-03-14 2017-09-05 Cardiovascular Systems, Inc. Devices, systems and methods for an oscillating crown drive for rotational atherectomy
US9936970B2 (en) 2013-03-14 2018-04-10 Cardiovascular Systems, Inc. Devices, systems and methods for an oscillating crown drive for rotational atherectomy
US9468457B2 (en) 2013-09-30 2016-10-18 Cardiovascular Systems, Inc. Atherectomy device with eccentric crown
USD766433S1 (en) 2013-11-04 2016-09-13 Cardiovascular Systems, Inc. Eccentric crown
US10751083B2 (en) 2014-03-01 2020-08-25 Rex Medical L.P. Atherectomy device
US10271869B2 (en) 2014-03-01 2019-04-30 Rex Medical, L.P. Atherectomy device
US11426194B2 (en) 2014-12-27 2022-08-30 Rex Medical L.P. Atherectomy device
US10463389B2 (en) 2014-12-27 2019-11-05 Rex Medical, L.P. Atherectomy device
US11547434B2 (en) 2014-12-27 2023-01-10 Rex Medical L.P. Atherectomy device
US10433868B2 (en) 2014-12-27 2019-10-08 Rex Medical, L.P. Artherectomy device
US11253292B2 (en) 2015-09-13 2022-02-22 Rex Medical, L.P. Atherectomy device
US11020134B2 (en) 2016-03-26 2021-06-01 Rex Meddical L.P. Atherectomy device
US10307175B2 (en) 2016-03-26 2019-06-04 Rex Medical, L.P Atherectomy device
US11864780B2 (en) 2016-03-26 2024-01-09 Rex Medical, L.P. Atherectomy device
US11051842B2 (en) 2017-05-03 2021-07-06 Medtronic Vascular, Inc. Tissue-removing catheter with guidewire isolation liner
US11871958B2 (en) 2017-05-03 2024-01-16 Medtronic Vascular, Inc. Tissue-removing catheter with guidewire isolation liner
US10987126B2 (en) 2017-05-03 2021-04-27 Medtronic Vascular, Inc. Tissue-removing catheter with guidewire isolation liner
US11896260B2 (en) 2017-05-03 2024-02-13 Medtronic Vascular, Inc. Tissue-removing catheter
US10925632B2 (en) 2017-05-03 2021-02-23 Medtronic Vascular, Inc. Tissue-removing catheter
US11690645B2 (en) 2017-05-03 2023-07-04 Medtronic Vascular, Inc. Tissue-removing catheter
US10869689B2 (en) 2017-05-03 2020-12-22 Medtronic Vascular, Inc. Tissue-removing catheter
US11819236B2 (en) 2019-05-17 2023-11-21 Medtronic Vascular, Inc. Tissue-removing catheter
US11304723B1 (en) 2020-12-17 2022-04-19 Avantec Vascular Corporation Atherectomy devices that are self-driving with controlled deflection

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