US20020133192A1 - Temporary vascular filter - Google Patents

Temporary vascular filter Download PDF

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Publication number
US20020133192A1
US20020133192A1 US10/060,854 US6085402A US2002133192A1 US 20020133192 A1 US20020133192 A1 US 20020133192A1 US 6085402 A US6085402 A US 6085402A US 2002133192 A1 US2002133192 A1 US 2002133192A1
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United States
Prior art keywords
filter
catheter
mandrel
proximal
length
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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US10/060,854
Inventor
Richard Kusleika
Brian Finander
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Ev3 Inc
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Microvena Corp
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Publication date
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Priority to US10/060,854 priority Critical patent/US20020133192A1/en
Publication of US20020133192A1 publication Critical patent/US20020133192A1/en
Assigned to EV3 INC. reassignment EV3 INC. MERGER (SEE DOCUMENT FOR DETAILS). Assignors: MICROVENA CORPORATION
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01Filters implantable into blood vessels
    • A61F2/0108Both ends closed, i.e. legs gathered at both ends
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01Filters implantable into blood vessels
    • A61F2/013Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • A61B2017/2212Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions having a closed distal end, e.g. a loop
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01Filters implantable into blood vessels
    • A61F2002/016Filters implantable into blood vessels made from wire-like elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01Filters implantable into blood vessels
    • A61F2002/018Filters implantable into blood vessels made from tubes or sheets of material, e.g. by etching or laser-cutting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004Rounded shapes, e.g. with rounded corners
    • A61F2230/0006Rounded shapes, e.g. with rounded corners circular
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0069Three-dimensional shapes cylindrical

Definitions

  • the present invention generally relates to filters for body passageways, and has particular utility in connection with temporary vascular filters.
  • Filters can be deployed in channels or vessels in patients bodies in a variety of medical procedures or in treating certain conditions. For example, rotating burrs are used in removing atheroma from the lumen of patients' blood vessels. These burrs can effectively dislodge the atheroma, but the dislodged material will simply float downstream with the flow of blood through the vessel. Filters can be used to capture such dislodged material before it is allowed to drift too far downstream, possibly occluding blood flow through a more narrow vessel.
  • this trap is optimally carried on a mandrel 260 further enhances its utility as most common angioplasty balloons and atherectomy devices are used in conjunction with such mandrels. While this trap is very useful and shows great promise in many common procedures, it may be possible to better retain the thrombi collected in the filter during retrieval of the filter.
  • the present invention provides a method of deploying a medical filter within a channel in a patients body and devices which are well suited for use in such procedures.
  • a filter and retrieval catheter are provided.
  • This filter has a radially expandable body having proximal and distal ends and which defines an enclosure.
  • the expandable body has a distal length and a proximal length which includes an opening therein.
  • the retrieval catheter has a lumen with a diameter less than the maximum dimension of the body's expanded configuration. This filter is urged along a length of the channel in the patient's body with the filter body in a radially reduced configuration.
  • the body is radially expanded to its expanded configuration such that it substantially fills the lumen of the vessel and the opening in the body is oriented proximally.
  • Body fluid is permitted to enter the enclosure through this proximally oriented opening and is permitted to pass through the distal length of the body.
  • the distal length of the body filters from the body fluid particulate material entrained therein (assuming, of course, that there is any such particulate material of an appropriate size).
  • the proximal length of the body is drawn within the lumen of the catheter, thereby effectively closing the proximally oriented opening within the retrieval sheath to retain said particulate material within the enclosure.
  • the filter has a narrow proximal end which is smaller than the lumen of the catheter.
  • this narrow proximal end may be introduced into the distal end of the catheter's lumen.
  • the filter may then be retracted until the internal surface of the catheter engages the body of the filter distally of the opening to effectively create a particulate seal therebetween.
  • such a device comprises a collapsible filter system including a mandrel and a filter.
  • the mandrel has proximal and distal ends and the filter is carried along the mandrel between these ends.
  • the filter has a radially expandable body having proximal and distal ends of its own.
  • the body is formed of a porous, resilient fabric having pores therein through which a body fluid may pass, but which are small enough to restrict passage of particulate material over a certain, predetermined size entrained in the body fluid.
  • a proximally oriented hole passes through the fabric along a proximal length of the filter's body. This hole is spaced distally of the proximal end of the body and being at least about five times the size of said pores.
  • FIG. 1 is a perspective view of a medical filter in accordance with one embodiment of the present invention.
  • FIG. 2 is a side elevation view of the filter of FIG. 1;
  • FIG. 3 is a cross sectional view of the medical filter of claim 1 , taken along line 3 - 3 of FIG. 2;
  • FIG. 4 is a schematic side view in partial cross section illustrating a filter of an alternative embodiment of the invention in a radially reduced configuration within a catheter
  • FIG. 5 is a schematic side view illustrating the filter of FIG. 4 deployed in a vessel in a patient's body
  • FIG. 6 is a schematic side view of the filter of FIGS. 4 and 5 with collected particulate material trapped within the filter;
  • FIG. 7 is a schematic side view of the filter of FIGS. 4 - 6 drawn far enough into the catheter to effectively close the proximally oriented opening within the catheter, and
  • FIG. 8 is a schematic side view of the filter of FIGS. 4 - 7 withdrawn completely within the lumen of the catheter.
  • FIGS. 1 - 3 illustrate a filter system 10 in accordance with one embodiment of the invention.
  • This filter system can be used in any channel in a patient's body, including blood vessels, the urinary tract or biliary tract and airways.
  • This filter system 10 is optimally designed to be deployed in a patient's vessel in a minimally invasive procedure, such as by introducing the filter system into a blood vessel through a catheter (as described in greater detail below).
  • the filter system 10 of the invention generally includes a mandrel 20 and a filter 50 .
  • the mandrel 20 can be thought of as having a primary function of positioning and controlling the deployment of the filter 50 while the filter can be considered the primary therapeutic or functional element of the system 10 .
  • the mandrel 20 should be fairly flexible to allow the device to be deployed in a curving body passageway without kinking or otherwise inhibiting suitable deployment of the filter 50 .
  • the mandrel can be formed of any material having any dimension suitable for the task for which the filter system 10 is to be employed, in most circumstances, the mandrel 20 will comprise an elongate metal wire.
  • the mandrel 20 is formed of nitinol, a roughly stoichiometric alloy of nickel and titanium having excellent “superelastic” properties.
  • the use of nitinol in medical guidewires and related applications is well known in the art and need not be discussed in detail here.
  • the distal-most length of the mandrel may include a flexible helically wound coil 22 extending thereover. The use of such helical coils to enhance flexibility of the distal tip is well known in the guidewire art.
  • the mandrel 20 shown in FIGS. 1 - 3 has an enlarged diameter stop 40 attached thereto.
  • the stop 40 is spaced proximally from the distal tip 25 of the mandrel 20 .
  • the stop 40 is spaced proximally of the proximal end of the helical coil 22 of the mandrel. This permits the distal slider 60 of the filter 50 to slide relatively freely and unencumbered along the length of the mandrel distally of the stop.
  • the stop 40 can be formed of any desired material and can be attached to the mandrel 20 in any desired fashion.
  • the stop should be attached to the mandrel relatively securely, though, as the stop will be used to urge the filter 50 within the lumen of the vessel in which the system 10 is to be deployed.
  • the stop 40 may comprise a standard radiopaque marker band which has been securely crimped on the mandrel 20 and/or attached to the mandrel using an adhesive or solder.
  • the precise length and shape of the stop 40 is not critical.
  • the drawings illustrate the stop 40 as a relatively short cylindrical body attached about the circumference of the mandrel. However, the stop 40 may have a more bulbous shape and could, in theory, even be formed integrally with the mandrel.
  • the stop 40 effectively divides the mandrel into distal and proximal lengths.
  • the distal length 30 of the mandrel can be thought of as that length which extends distally from the stop 40 to the distal tip 25 of the mandrel.
  • the proximal portion 35 of the mandrel 20 can be thought of as comprising the length of the mandrel extending proximally from the stop 40 to the proximal end of the mandrel.
  • the filter 50 shown in FIGS. 1 - 3 has an elongate, generally tubular body 52 which extends from a distal slider 60 proximally to a proximal slider 65 .
  • the body 52 of the filter can be formed of any material suitable for the application at hand.
  • the filter body 52 typically comprises a length of a braided tubular fabric.
  • the use of a tubular braid of nitinol to make medical devices is described in some detail in International Publication No. WO 96/01591, the teachings of which were incorporated above by reference.
  • this process can employ a tubular braid of a fabric comprising two sets of nitinol wires wrapped helically about a mandrel, with one set of wires being wrapped spirally about the mandrel in one direction and the other set being wrapped in the other direction.
  • This braid is then placed in contact with a molding surface of a molding element which defines the shape of the desired functional element.
  • the body 52 of the filter 50 desirably is made of a fairly flexible, resilient material.
  • the filter 52 desirably has a radially expanded configuration, e.g., the shape shown in FIGS. 1 - 3 , which the device will tend to resiliently assume in the absence of any countervailing biasing force.
  • a body 52 formed of a nitinol tubular braid which has been heat set into the desired shape should suit this purpose well.
  • the body 52 of the filter 50 assumes a generally tubular shape having tapered proximal and distal ends.
  • the maximum outer diameter of the middle length of the body 52 should be sized to substantially fill the lumen of a vessel to ensure that the filter will effectively preclude any emboli (or other particulate material which may be entrained in the patient's bloodstream) from passing around the filter.
  • the body of the filter includes a distal length 53 and a proximal length 54 , each of which tapers from the middle of the body's length to their respective ends.
  • the distal length 53 tapers distally toward a narrow distal end adjacent the distal slider 60 while the proximal length 54 of the filter body tapers toward its proximal end adjacent the proximal slider 65 .
  • the rate of this tapering can be varied as desired. While FIGS. 1 - 3 illustrate a fairly gradual taper, the change in diameter may be more abrupt.
  • the filter body 52 of FIGS. 1 - 3 is also fairly symmetrical, with the tapers of the proximal and distal lengths being about the same. In some circumstances it may be advantageous to have the two lengths taper differently, e.g. where the proximal length tapers more gradually while the distal length changes diameter more abruptly.
  • the proximal length 54 of the filter body has at least one proximally oriented opening 56 therein.
  • This opening passes through the flexible, resilient fabric of which the body 52 desirably is formed.
  • the fabric has pores therein which allow fluids to pass therethrough, but the pores are small enough to prevent passage of particles larger than a predetermined size.
  • the maximum sizes of these pores can be controlled by adjusting the number of wires in the braid and the pick and pitch of the braid.
  • a pore size of 20-1500 microns is desirable.
  • such a filter body has a maximum diameter of about 4 mm, it may be formed of 48 wires each having a diameter of about 0.002 inches (about 50 microns) and a pick rate of about 90 per inch (about 35 per centimer).
  • the size of the proximally oriented opening 56 should be sufficient to permit body fluid with particulate material entrained therein to enter the enclosure within the body 52 of the filter. At a minimum, it is expected that the opening will be at leas five times the maximum pore size of the fabric of which the body is formed, with an opening of at least ten times the maximum pore size being preferred.
  • the opening 56 can be formed in any suitable fashion. If the filter is formed from a preformed flat sheet of fabric wrapped into the desired shape, the opening can be cut through the fabric before the fabric is shaped into the filter body. If the body 52 is formed of a tubular metallic braid, it may instead be cut through the fabric after the braid is heat set in the desired shape.
  • a tubular metal braid is provided.
  • the distal and proximal sliders 60 , 65 are attached to the braid a suitable distance from one another.
  • the braid is trimmed at the distal end of the distal slider 60 and at the proximal end of the proximal slider 65 .
  • a forming mandrel (not shown) is passed between the wire strands of the braid and positioned within the tubular braid.
  • the forming mandrel has an external molding surface which generally coincides with the desired shape of the filter body.
  • the forming mandrel may have a larger diameter than the inner diameter of the tubular braid and the braid may be drawn down against the forming mandrel by applying axial tension to the braid.
  • This structure may be heated at an elevated temperature to heat-set the filter body 52 in this shape and the forming mandrel may be removed.
  • the forming mandrel includes a proximal projection having a periphery the size and shape of the desired proximal opening 56 .
  • This projection extends through the wire mesh of the tubular braid during heat treatment, forcing the wire strands to extend about the periphery of the projection.
  • the wires will retain the proximal opening without requiring cutting the fabric.
  • the filter 50 is shown as having a single opening 56 extending over only one side of the proximal length 54 of the filter body (i.e., above the mandrel 20 in FIG. 2).
  • the number of openings or the shape of the opening(s) can be adjusted to maximize the cross sectional area of the vessel covered by the openings.
  • a plurality of openings can be spaced equiangularly about the proximal length 54 , such as three openings arranged about 120 degrees from one another.
  • the opening 56 in FIGS. 1 - 3 is generally elliptical with a major axis extending generally in a plane which contains the axis of the mandrel 20 . If one were to increase coverage of the opening 56 by adjusting its shape, the strength of the filter and its connection to the proximal slider 65 should not be compromised. One way to accomplish this is to offset the filter 50 with respect to the mandrel 20 .
  • the body 52 of the filter is generally symmetrical about a central longitudinal axis and this axis generally coincides with the axis of the mandrel.
  • the mandrel could extend adjacent to one side of the body and the opposite side of the body would extend farther from the mandrel.
  • the opening 56 By positioning the opening 56 on the larger side of the body, the opening can be made larger and cover more of the cross sectional area of the vessel in which the filter is deployed.
  • the opening 56 can extend up to or even into the proximal slider 65 , in a preferred embodiment the opening 56 is spaced distally from the slider 65 and the proximal end of the body 52 . This will enable a more secure connection between the slider 65 and the body.
  • the distal end of the opening desirably terminates proximally of the location where the filter body has its maximum diameter. This will minimize the chance that body fluid could slip between the filter and the wall of the vessel in which the filter is deployed. This will also provide a more effective seal between the filter body 52 and the catheter in which it is retrieved. (Such retrieval is discussed below in connection with FIGS. 7 and 8.)
  • the filter 50 is attached to or carried by the mandrel 20 by means of a proximal slider 65 attached to the body 52 adjacent its proximal end and a distal slider 60 attached adjacent the distal end of the body 52 .
  • the distal slider 60 should be free to slide along at least a proximal portion of the distal length 30 of the mandrel while the proximal slider 65 should be free to slide along at least a distal portion of the proximal length 35 of the mandrel.
  • the stop 40 of the mandrel effectively defines a limit on the range of motion of these sliders 60 , 65 .
  • each of the sliders 60 , 65 should be slidable along its respective length of the mandrel, the sliders can take any desired shape.
  • each slider comprises a relatively thin ring which is carried about the mandrel.
  • the thin ring can be attached to the body 52 in any desired fashion, such as by crimping or swaging the fabric of the body between two layers of the ring or soldering, welding or otherwise adhering the fabric to the ring.
  • the stop 40 of the mandrel is positioned within the body 52 of the filter and is not exerting any biasing force on either of the sliders 60 , 65 .
  • the mandrel 20 can be moved proximally and distally with respect to the filter 50 without substantially affecting the shape or position of the filter.
  • the limits of this range of free movement of the mandrel with respect to the filter are generally defined by the relationship between the stop 40 and the sliders 60 , 65 .
  • the mandrel can be moved from a distal position wherein the stop 40 abuts but does not exert any force on the distal slider 60 and a proximal position wherein the stop 40 abuts, but does not exert any significant force on, the proximal slider 65 .
  • the inner diameter of the generally annular collars defining the sliders 60 , 65 is desirably larger than the outer diameter of the mandrel, but should be smaller than the outer diameter of the stop 40 .
  • the stop serves as an effective limit on proximal movement of the distal slider 60 and distal movement of the proximal slider 65 .
  • the proximal and distal sliders are slidable along the mandrel essentially independently of one another.
  • the stop will exert a distal biasing force against the distal end of the body 52 of the filter.
  • the filter would travel with the mandrel without any appreciable alteration in the shape of the body 52 . In most clinical applications, though, this is not the case. Instead, there is typically some force restraining completely free movement of the filter within the channel of the patient's body.
  • the body 52 of the filter will resiliently expand into physical contact with the interior surface of the vessel within which it is deployed.
  • the stop 40 of the mandrel will abut against, and exert a proximal biasing force on, the proximal slider 65 of the filter 50 .
  • This proximal biasing force will act against the restorative force of the body 52 to axially elongate and radially reduce that body. This permits the device to be withdrawn proximally along the lumen of the vessel either for repositioning at a more proximal location or for withdrawal from the patient's body at the end of the procedure.
  • the proximal and distal sliders 60 , 65 are free to move relatively independently of one another, limited primarily by their indirect link to one another through the body 52 of the filter.
  • the proximal slider will slide proximally along the proximal length 35 of the mandrel.
  • the distal slider will be free to drift distally along the distal length 30 of the mandrel.
  • FIGS. 4 - 8 schematically depict one method of the invention utilizing an alternative filter design.
  • Most of the elements of the filter 50 ′ in FIGS. 4 - 8 are essentially the same as like elements in FIGS. 1 - 3 , so the same reference numbers have been used for most elements in both sets of drawings.
  • the primary differences between the filter 50 ′ of FIGS. 4 - 8 and the filter 50 described above is that the stop 40 has been omitted in FIGS. 4 - 8 and the proximal slider 65 ′ has been secured to the mandrel 20 at a fixed location. The distal slider 60 remains free to slide along the mandrel.
  • the body 52 ′ of the filter 50 ′ is shaped a little differently from the filter body 52 of FIGS. 1 - 3 . This difference is not crucial and does not yield significantly different properties. Instead, the differences in the fully deployed shapes of the two filters 50 , 50 ′ are intended to highlight that the shape can vary without compromising the filter's function.
  • FIG. 4 schematically illustrates the filter 50 ′ collapsed within the lumen of a catheter C.
  • the body 52 ′ of the filter has been collapsed under the biasing force of the catheter walls into an axially elongated, radially reduced configuration.
  • This catheter and filter combination may be advanced through a patient's body as a unit until a specific treatment site has been reached, but this combined unit may be difficult to steer through a more tortuous path.
  • the catheter will first be positioned adjacent the treatment site.
  • the filter 50 ′ can be deployed out the distal end of the catheter.
  • the filter 50 ′ may be urged out of the distal end of the catheter, e.g., by holding the catheter C still and urging the mandrel 20 distally or by holding the mandrel 20 stationary and withdrawing the catheter C proximally.
  • the flexible body 52 Upon exiting the distal end of the catheter C, the flexible body 52 will resiliently expand radially outwardly, desirably until it engages the wall of the vessel V or, less desirably, is positioned adjacent to the vessel wall. (Such a configuration is shown in FIG. 5.) This will help ensure that all fluid passing along the vessel V will have to pass through the filter body 52 ′.
  • a substantial portion (ideally, all or at least a vast majority) of the body fluid in the vessel should pass through the proximally oriented opening 56 in the filter body. Since the opening is fairly large, it is anticipated that any particulate material entrained in the body fluid travelling through the vessel will enter the interior of the filter through the opening 56 .
  • the pores in the distal length 53 of the filter body are significantly smaller, though, so most oversized particles will be trapped within the enclosure of the filter body.
  • FIG. 6 schematically depicts such a situation, with a number of individual particles P being shown trapped within the filter body. If the filter 50 or 50 ′ is to be used in a vascular procedure, the pores should be large enough to permit red blood cells to pass therethrough, but small enough to trap thrombi or emboli above a certain predetermined size.
  • vascular filters A wide variety of vascular filters are known in the art and thee with which such filters can be deployed varies.
  • One of the primary distinguishing characteristics between these various filter designs is the ease with which the filters can be withdrawn from or repositioned within the patient's body.
  • most commercially available vena cava filters are provided with sharp barbs or other structures which firmly seat the devices in a wall of the vessel, but which effectively preclude retraction of the device.
  • Temporary filters avoid such tenacious attachments to the vessel wall, permitting them to be retracted or moved after initial deployment.
  • one of the primary difficulties encountered in using such temporary filters is the risk of dumping the captured particulate material back into the vessel from which it was filtered.
  • Many designs require that the physician first aspirate the particulate material or, in the case of thrombi captured in vascular procedures, use drugs which help break down the particles to clinically acceptable sizes.
  • FIG. 7 shows the filter 50 ′ of FIGS. 4 - 6 partially retracted into the catheter C. If the filter is being used for only a short period of time, the catheter C may be the same catheter used to initially deploy the filter in the vessel. If the filter is to be left in place for a longer period of time, though, it may be preferred to remove the deployment catheter (FIG. 4) from the patient's body and later introduce a separate retrieval catheter by advancing the retrieval catheter along the mandrel 20 .
  • the lumen of the retrieval catheter C in FIG. 7 has a diameter smaller than the maximum cross-sectional dimension of the body's expanded configuration.
  • the lumen is larger than the narrow proximal end of the filter body 52 ′ adjacent the proximal slider 65 ′, though, and the illustrated filter body is spaced from the vessel wall about its entire periphery.
  • the distal tip of the catheter can be positioned between the proximal end of the body 52 ′ and the wall of the vessel V before the catheter engages the body of the filter adjacent the slider. This can be done by holding the catheter in place and withdrawing the mandrel proximally, by holding the mandrel stationary and moving the catheter distally, or moving both the catheter and the mandrel.
  • the rest of the body can be drawn into the lumen of the catheter. Again, the body can be drawn into the catheter by advancing the catheter distally or retracing the filter proximally. At some point, the wall of the catheter C will engage the larger diameter body 52 . Ideally, the lumen of the catheter is notably smaller than the deployed diameter of the filter body. As shown in FIG. 7, in this case the walls of the catheter will exert a biasing force to urge the body toward the radially reduced configuration in which it was initially deployed (FIG. 4).
  • the internal surface of the catheter engages the body of the filter distally of the filter's proximally oriented opening 56 . While the opening may still be open to the lumen of the catheter, the engagement between the filer body and the catheter wall distally of the opening effectively creates a particulate seal therebetween. As a consequence, simply by advancing the catheter C with respect to the filter 50 ′, one can seal within the combined catheter and filter all of the captured particles above the predetermined minimum size. This combination can then be moved as a unit either to remove it from or reposition it within the patient's body with minimal risk of losing any of the captured particles.
  • the filter body 52 ′ be completely withdrawn into the lumen of the catheter (as shown in FIG. 8) rather than leaving a distal section of the filter extending out of the catheter (as shown in FIG. 7). This will reduce friction against the vessel wall, making withdrawal easier and reducing trauma to the intima of the vessel.

Abstract

The present invention provides a method of deploying a medical filter within a channel in a patient's body and filter systems which can be used in such a method. Such a filter may include a radially expandable body 52 having an opening 56 in a proximal length thereof. In one method, the filter is urged along a length of the channel with the filter body in a radially reduced configuration. This body is expanded to substantially fill the lumen of the vessel and orient the opening in the body proximally. Body fluid is permitted to enter the filter body through the proximally oriented opening and pass distally through the distal length of the body so that the distal length of the body filters from the body fluid particulate material entrained therein. The proximal length of the body can be drawn into the retrieval catheter, thereby effectively closing the proximally oriented opening within the catheter to retain the particulate material within the enclosure. In a preferred embodiment, the filter body 52 is formed of a porous, resilient fabric having pores therein and the proximal opening 56 is at least five times the size of such pores.

Description

    FIELD OF THE INVENTION
  • The present invention generally relates to filters for body passageways, and has particular utility in connection with temporary vascular filters. [0001]
  • BACKGROUND OF THE INVENTION
  • Filters can be deployed in channels or vessels in patients bodies in a variety of medical procedures or in treating certain conditions. For example, rotating burrs are used in removing atheroma from the lumen of patients' blood vessels. These burrs can effectively dislodge the atheroma, but the dislodged material will simply float downstream with the flow of blood through the vessel. Filters can be used to capture such dislodged material before it is allowed to drift too far downstream, possibly occluding blood flow through a more narrow vessel. [0002]
  • Some researchers have proposed various traps or filters for capturing the particulate matter released or created in such procedures. However, most such filters generally have not proven to be exceptionally effective in actual use. These filters tend to be cumbersome to use and accurate deployment is problematic because if they are not properly seated in the vessel they can drift to a more distal site where they are likely to do more harm than good. In addition, these filters are generally capable of only trapping relatively large thrombi and are not effective for removing smaller embolic particles from the blood stream. [0003]
  • The problems with most temporary filters, which are intended to be used only during a particular procedure then retracted with the thrombi trapped therein, are more pronounced. Even if the trap does effectively capture the dislodged material, it has proven to be relatively difficult or complex to retract the trap back into the catheter through which it was delivered without simply dumping the trapped thrombi back into the blood stream, defeating the purpose of the temporary filter device. For this reason, most atherectomy devices and the like tend to aspirate the patient's blood during the procedure to remove the dislodged material entrained therein. [0004]
  • One promising filter design which overcomes many of these difficulties is shown in International Publication No. WO 96/01591 (the publication of PCT International Application No. PCT/US95/08613), the teachings of which are incorporated herein by reference. Generally, this reference teaches a trap which can be used to filter particles from blood or other fluid moving through a body vessel. In one illustrated embodiment, this trap includes a basket [0005] 270 which can be deployed and retracted through a catheter or the like, making it particularly suitable for use in minimally invasive procedures such as angioplasty or atherectomy procedures. The fact that this trap is optimally carried on a mandrel 260 further enhances its utility as most common angioplasty balloons and atherectomy devices are used in conjunction with such mandrels. While this trap is very useful and shows great promise in many common procedures, it may be possible to better retain the thrombi collected in the filter during retrieval of the filter.
  • SUMMARY OF THE INVENTION
  • The present invention provides a method of deploying a medical filter within a channel in a patients body and devices which are well suited for use in such procedures. In accordance with one method of the invention, a filter and retrieval catheter are provided. This filter has a radially expandable body having proximal and distal ends and which defines an enclosure. The expandable body has a distal length and a proximal length which includes an opening therein. The retrieval catheter has a lumen with a diameter less than the maximum dimension of the body's expanded configuration. This filter is urged along a length of the channel in the patient's body with the filter body in a radially reduced configuration. The body is radially expanded to its expanded configuration such that it substantially fills the lumen of the vessel and the opening in the body is oriented proximally. Body fluid is permitted to enter the enclosure through this proximally oriented opening and is permitted to pass through the distal length of the body. In so doing, the distal length of the body filters from the body fluid particulate material entrained therein (assuming, of course, that there is any such particulate material of an appropriate size). The proximal length of the body is drawn within the lumen of the catheter, thereby effectively closing the proximally oriented opening within the retrieval sheath to retain said particulate material within the enclosure. [0006]
  • Further refinements of this method are envisioned. For example, in one embodiment, the filter has a narrow proximal end which is smaller than the lumen of the catheter. In drawing the proximal length of the filter within the catheter, this narrow proximal end may be introduced into the distal end of the catheter's lumen. The filter may then be retracted until the internal surface of the catheter engages the body of the filter distally of the opening to effectively create a particulate seal therebetween. [0007]
  • As noted above, the present invention also encompasses a device well suited for use in such procedures. In one embodiment, such a device comprises a collapsible filter system including a mandrel and a filter. The mandrel has proximal and distal ends and the filter is carried along the mandrel between these ends. The filter has a radially expandable body having proximal and distal ends of its own. The body is formed of a porous, resilient fabric having pores therein through which a body fluid may pass, but which are small enough to restrict passage of particulate material over a certain, predetermined size entrained in the body fluid. A proximally oriented hole passes through the fabric along a proximal length of the filter's body. This hole is spaced distally of the proximal end of the body and being at least about five times the size of said pores. [0008]
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • FIG. 1 is a perspective view of a medical filter in accordance with one embodiment of the present invention; [0009]
  • FIG. 2 is a side elevation view of the filter of FIG. 1; [0010]
  • FIG. 3 is a cross sectional view of the medical filter of claim [0011] 1, taken along line 3-3 of FIG. 2;
  • FIG. 4 is a schematic side view in partial cross section illustrating a filter of an alternative embodiment of the invention in a radially reduced configuration within a catheter, [0012]
  • FIG. 5 is a schematic side view illustrating the filter of FIG. 4 deployed in a vessel in a patient's body; [0013]
  • FIG. 6 is a schematic side view of the filter of FIGS. 4 and 5 with collected particulate material trapped within the filter; [0014]
  • FIG. 7 is a schematic side view of the filter of FIGS. [0015] 4-6 drawn far enough into the catheter to effectively close the proximally oriented opening within the catheter, and
  • FIG. 8 is a schematic side view of the filter of FIGS. [0016] 4-7 withdrawn completely within the lumen of the catheter.
  • DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
  • FIGS. [0017] 1-3 illustrate a filter system 10 in accordance with one embodiment of the invention. This filter system can be used in any channel in a patient's body, including blood vessels, the urinary tract or biliary tract and airways. This filter system 10 is optimally designed to be deployed in a patient's vessel in a minimally invasive procedure, such as by introducing the filter system into a blood vessel through a catheter (as described in greater detail below).
  • The [0018] filter system 10 of the invention generally includes a mandrel 20 and a filter 50. Conceptually, the mandrel 20 can be thought of as having a primary function of positioning and controlling the deployment of the filter 50 while the filter can be considered the primary therapeutic or functional element of the system 10.
  • The [0019] mandrel 20 should be fairly flexible to allow the device to be deployed in a curving body passageway without kinking or otherwise inhibiting suitable deployment of the filter 50. While the mandrel can be formed of any material having any dimension suitable for the task for which the filter system 10 is to be employed, in most circumstances, the mandrel 20 will comprise an elongate metal wire. In one particularly preferred embodiment, the mandrel 20 is formed of nitinol, a roughly stoichiometric alloy of nickel and titanium having excellent “superelastic” properties. The use of nitinol in medical guidewires and related applications is well known in the art and need not be discussed in detail here. If so desired, the distal-most length of the mandrel may include a flexible helically wound coil 22 extending thereover. The use of such helical coils to enhance flexibility of the distal tip is well known in the guidewire art.
  • The [0020] mandrel 20 shown in FIGS. 1-3 has an enlarged diameter stop 40 attached thereto. The stop 40 is spaced proximally from the distal tip 25 of the mandrel 20. Desirably, the stop 40 is spaced proximally of the proximal end of the helical coil 22 of the mandrel. This permits the distal slider 60 of the filter 50 to slide relatively freely and unencumbered along the length of the mandrel distally of the stop.
  • The [0021] stop 40 can be formed of any desired material and can be attached to the mandrel 20 in any desired fashion. The stop should be attached to the mandrel relatively securely, though, as the stop will be used to urge the filter 50 within the lumen of the vessel in which the system 10 is to be deployed. As an example, the stop 40 may comprise a standard radiopaque marker band which has been securely crimped on the mandrel 20 and/or attached to the mandrel using an adhesive or solder. The precise length and shape of the stop 40 is not critical. The drawings illustrate the stop 40 as a relatively short cylindrical body attached about the circumference of the mandrel. However, the stop 40 may have a more bulbous shape and could, in theory, even be formed integrally with the mandrel.
  • The [0022] stop 40 effectively divides the mandrel into distal and proximal lengths. The distal length 30 of the mandrel can be thought of as that length which extends distally from the stop 40 to the distal tip 25 of the mandrel. Likewise, the proximal portion 35 of the mandrel 20 can be thought of as comprising the length of the mandrel extending proximally from the stop 40 to the proximal end of the mandrel.
  • The [0023] filter 50 shown in FIGS. 1-3 has an elongate, generally tubular body 52 which extends from a distal slider 60 proximally to a proximal slider 65. The body 52 of the filter can be formed of any material suitable for the application at hand. In many applications, e.g., filtering blood within a patient's vasculature, the filter body 52 typically comprises a length of a braided tubular fabric. The use of a tubular braid of nitinol to make medical devices is described in some detail in International Publication No. WO 96/01591, the teachings of which were incorporated above by reference. Briefly speaking though, this process can employ a tubular braid of a fabric comprising two sets of nitinol wires wrapped helically about a mandrel, with one set of wires being wrapped spirally about the mandrel in one direction and the other set being wrapped in the other direction. This braid is then placed in contact with a molding surface of a molding element which defines the shape of the desired functional element. By heat treating the fabric in contact with the molding surface of the molding element, one can create a functional element having virtually any desired shape.
  • The [0024] body 52 of the filter 50 desirably is made of a fairly flexible, resilient material. In particular, the filter 52 desirably has a radially expanded configuration, e.g., the shape shown in FIGS. 1-3, which the device will tend to resiliently assume in the absence of any countervailing biasing force. A body 52 formed of a nitinol tubular braid which has been heat set into the desired shape should suit this purpose well.
  • In the [0025] filter system 10 shown in FIGS. 1-3, the body 52 of the filter 50 assumes a generally tubular shape having tapered proximal and distal ends. The maximum outer diameter of the middle length of the body 52 should be sized to substantially fill the lumen of a vessel to ensure that the filter will effectively preclude any emboli (or other particulate material which may be entrained in the patient's bloodstream) from passing around the filter.
  • The body of the filter includes a [0026] distal length 53 and a proximal length 54, each of which tapers from the middle of the body's length to their respective ends. In particular, the distal length 53 tapers distally toward a narrow distal end adjacent the distal slider 60 while the proximal length 54 of the filter body tapers toward its proximal end adjacent the proximal slider 65. The rate of this tapering can be varied as desired. While FIGS. 1-3 illustrate a fairly gradual taper, the change in diameter may be more abrupt. The filter body 52 of FIGS. 1-3 is also fairly symmetrical, with the tapers of the proximal and distal lengths being about the same. In some circumstances it may be advantageous to have the two lengths taper differently, e.g. where the proximal length tapers more gradually while the distal length changes diameter more abruptly.
  • The [0027] proximal length 54 of the filter body has at least one proximally oriented opening 56 therein. This opening passes through the flexible, resilient fabric of which the body 52 desirably is formed. The fabric has pores therein which allow fluids to pass therethrough, but the pores are small enough to prevent passage of particles larger than a predetermined size. If the body is formed of a metallic tubular braid as mentioned above, the maximum sizes of these pores can be controlled by adjusting the number of wires in the braid and the pick and pitch of the braid. For example, if the filter 50 is to be employed as a vascular filter, a pore size of 20-1500 microns is desirable. If such a filter body has a maximum diameter of about 4 mm, it may be formed of 48 wires each having a diameter of about 0.002 inches (about 50 microns) and a pick rate of about 90 per inch (about 35 per centimer).
  • The size of the proximally oriented opening [0028] 56 should be sufficient to permit body fluid with particulate material entrained therein to enter the enclosure within the body 52 of the filter. At a minimum, it is expected that the opening will be at leas five times the maximum pore size of the fabric of which the body is formed, with an opening of at least ten times the maximum pore size being preferred.
  • The [0029] opening 56 can be formed in any suitable fashion. If the filter is formed from a preformed flat sheet of fabric wrapped into the desired shape, the opening can be cut through the fabric before the fabric is shaped into the filter body. If the body 52 is formed of a tubular metallic braid, it may instead be cut through the fabric after the braid is heat set in the desired shape.
  • In one particularly preferred method of forming the filter (which method comprises another embodiment of the invention), a tubular metal braid is provided. The distal and [0030] proximal sliders 60, 65 are attached to the braid a suitable distance from one another. The braid is trimmed at the distal end of the distal slider 60 and at the proximal end of the proximal slider 65. A forming mandrel (not shown) is passed between the wire strands of the braid and positioned within the tubular braid.
  • The forming mandrel has an external molding surface which generally coincides with the desired shape of the filter body. The forming mandrel may have a larger diameter than the inner diameter of the tubular braid and the braid may be drawn down against the forming mandrel by applying axial tension to the braid. This structure may be heated at an elevated temperature to heat-set the [0031] filter body 52 in this shape and the forming mandrel may be removed.
  • The forming mandrel includes a proximal projection having a periphery the size and shape of the desired [0032] proximal opening 56. This projection extends through the wire mesh of the tubular braid during heat treatment, forcing the wire strands to extend about the periphery of the projection. As a consequence of the heat treatment, when the forming mandrel is removed, the wires will retain the proximal opening without requiring cutting the fabric.
  • In FIGS. [0033] 1-3, the filter 50 is shown as having a single opening 56 extending over only one side of the proximal length 54 of the filter body (i.e., above the mandrel 20 in FIG. 2). To increase the percentage of body fluid which passes into the enclosure of the filter body, the number of openings or the shape of the opening(s) can be adjusted to maximize the cross sectional area of the vessel covered by the openings. For example, a plurality of openings can be spaced equiangularly about the proximal length 54, such as three openings arranged about 120 degrees from one another.
  • The [0034] opening 56 in FIGS. 1-3 is generally elliptical with a major axis extending generally in a plane which contains the axis of the mandrel 20. If one were to increase coverage of the opening 56 by adjusting its shape, the strength of the filter and its connection to the proximal slider 65 should not be compromised. One way to accomplish this is to offset the filter 50 with respect to the mandrel 20. In FIGS. 1-3, the body 52 of the filter is generally symmetrical about a central longitudinal axis and this axis generally coincides with the axis of the mandrel. One could instead make the filter asymmetrical, with the axis of the mandrel 20 spaced radially outwardly from the central axis of the body 52. In such a design, the mandrel could extend adjacent to one side of the body and the opposite side of the body would extend farther from the mandrel. By positioning the opening 56 on the larger side of the body, the opening can be made larger and cover more of the cross sectional area of the vessel in which the filter is deployed.
  • While the [0035] opening 56 can extend up to or even into the proximal slider 65, in a preferred embodiment the opening 56 is spaced distally from the slider 65 and the proximal end of the body 52. This will enable a more secure connection between the slider 65 and the body. The distal end of the opening desirably terminates proximally of the location where the filter body has its maximum diameter. This will minimize the chance that body fluid could slip between the filter and the wall of the vessel in which the filter is deployed. This will also provide a more effective seal between the filter body 52 and the catheter in which it is retrieved. (Such retrieval is discussed below in connection with FIGS. 7 and 8.)
  • The [0036] filter 50 is attached to or carried by the mandrel 20 by means of a proximal slider 65 attached to the body 52 adjacent its proximal end and a distal slider 60 attached adjacent the distal end of the body 52. The distal slider 60 should be free to slide along at least a proximal portion of the distal length 30 of the mandrel while the proximal slider 65 should be free to slide along at least a distal portion of the proximal length 35 of the mandrel. In use, the stop 40 of the mandrel effectively defines a limit on the range of motion of these sliders 60, 65.
  • While each of the [0037] sliders 60, 65 should be slidable along its respective length of the mandrel, the sliders can take any desired shape. In the illustrated embodiments, each slider comprises a relatively thin ring which is carried about the mandrel. The thin ring can be attached to the body 52 in any desired fashion, such as by crimping or swaging the fabric of the body between two layers of the ring or soldering, welding or otherwise adhering the fabric to the ring.
  • The [0038] stop 40 of the mandrel is positioned within the body 52 of the filter and is not exerting any biasing force on either of the sliders 60, 65. In this configuration, the mandrel 20 can be moved proximally and distally with respect to the filter 50 without substantially affecting the shape or position of the filter. The limits of this range of free movement of the mandrel with respect to the filter are generally defined by the relationship between the stop 40 and the sliders 60, 65. In particular, the mandrel can be moved from a distal position wherein the stop 40 abuts but does not exert any force on the distal slider 60 and a proximal position wherein the stop 40 abuts, but does not exert any significant force on, the proximal slider 65. This allows the filter 50 (or any other functional element which is carried by the mandrel) to be fairly precisely positioned within a patient's vessel and retain that position even if the guidewire is moved slightly during use. This can be advantageous in circumstances where other devices are exchanged over the guidewire (e.g., during angioplasty and atherectomy procedures).
  • The inner diameter of the generally annular collars defining the [0039] sliders 60, 65 is desirably larger than the outer diameter of the mandrel, but should be smaller than the outer diameter of the stop 40. In this fashion, the stop serves as an effective limit on proximal movement of the distal slider 60 and distal movement of the proximal slider 65. Apart from this relationship with the slider 40 and the fact that both sliders are indirectly linked to one another by the body 52 of the filter, the proximal and distal sliders are slidable along the mandrel essentially independently of one another.
  • When the [0040] mandrel 20 is urged distally (to the left in FIGS. 2 and 3) against the distal slider 60, the stop will exert a distal biasing force against the distal end of the body 52 of the filter. In theory, if the filter were used in a frictionless environment, the filter would travel with the mandrel without any appreciable alteration in the shape of the body 52. In most clinical applications, though, this is not the case. Instead, there is typically some force restraining completely free movement of the filter within the channel of the patient's body. Typically (and. as suggested in FIGS. 5 and 6, for example), the body 52 of the filter will resiliently expand into physical contact with the interior surface of the vessel within which it is deployed. This contact with the vessel wall will tend to hold the filter 50 in place as the stop of the mandrel slides proximally and distally between the two sliders 60, 65. When the mandrel is urged distally until it exerts a distal force against the distal slider 60, this force will tend to axially elongate the body 52.
  • Resilient tubular braids tend to assume a radially reduced profile upon axial elongation. (This property and some of its implications are discussed in International Publication No. WO 96/01591, mentioned previously.) As a consequence, when the [0041] mandrel 20 is urged distally to push distally against the distal slider 60, this distal force acts against the restorative force of the resilient braid, which would otherwise bias the braid into its expanded configuration (FIGS. 1-3). By overcoming this restorative force with a countervailing distal force, the body 52 will tend to both axially elongate and assume a radially reduced profile. This, in turn, reduces the force with which the body engages the wall of the vessel or catheter in which the filter is positioned and reduces friction between the filter 50 and the vessel or catheter. Hence, urging the mandrel distally to move the filter 50 distally will, at the same time, reduce friction between the filter and the vessel wall to further facilitate advancement of the filter along the vessel's lumen. This requires less force to push the filter distally, enabling the mandrel to be smaller and reducing the outer diameter of the collapsed device, making deployment in smaller vessels feasible. In addition, the reduced friction between the filter and the vessel wall limits damage to the intima of the vessel, permitting the filter to be deployed and moved with a minimum of trauma.
  • When the mandrel is retracted proximally, the [0042] stop 40 of the mandrel will abut against, and exert a proximal biasing force on, the proximal slider 65 of the filter 50. This proximal biasing force will act against the restorative force of the body 52 to axially elongate and radially reduce that body. This permits the device to be withdrawn proximally along the lumen of the vessel either for repositioning at a more proximal location or for withdrawal from the patient's body at the end of the procedure.
  • In the embodiment of FIGS. [0043] 1-3, the proximal and distal sliders 60, 65 are free to move relatively independently of one another, limited primarily by their indirect link to one another through the body 52 of the filter. For example, when the mandrel 20 is urged distally against the distal slider 60 (FIG. 4), the proximal slider will slide proximally along the proximal length 35 of the mandrel. Similarly, when the mandrel is withdrawn proximally to urge proximally against the proximal slider 65, the distal slider will be free to drift distally along the distal length 30 of the mandrel. Ideally, there should be a sufficient distance between the distal shoulder of the stop 40 and the proximal end of the helical coil 22 at the distal end of the mandrel.
  • FIGS. [0044] 4-8 schematically depict one method of the invention utilizing an alternative filter design. Most of the elements of the filter 50′ in FIGS. 4-8 are essentially the same as like elements in FIGS. 1-3, so the same reference numbers have been used for most elements in both sets of drawings. The primary differences between the filter 50′ of FIGS. 4-8 and the filter 50 described above is that the stop 40 has been omitted in FIGS. 4-8 and the proximal slider 65′ has been secured to the mandrel 20 at a fixed location. The distal slider 60 remains free to slide along the mandrel.
  • The [0045] body 52′ of the filter 50′ is shaped a little differently from the filter body 52 of FIGS. 1-3. This difference is not crucial and does not yield significantly different properties. Instead, the differences in the fully deployed shapes of the two filters 50, 50′ are intended to highlight that the shape can vary without compromising the filter's function.
  • FIG. 4 schematically illustrates the [0046] filter 50′ collapsed within the lumen of a catheter C. The body 52′ of the filter has been collapsed under the biasing force of the catheter walls into an axially elongated, radially reduced configuration. This catheter and filter combination may be advanced through a patient's body as a unit until a specific treatment site has been reached, but this combined unit may be difficult to steer through a more tortuous path. For many applications (e.g., deployment at a remote site within a patient's vasculature), the catheter will first be positioned adjacent the treatment site. Only then will the filter system be inroduced into the distal end of the catheter C and urged along the catheters lumen and the vessel V until the distal end 25 of the mandrel and the distal slider 65 are positioned adjacent the distal end of the catheter, as shown in FIG. 4.
  • Regardless of how the system reaches the state illustrated in FIG. 4, once the catheter is in place the [0047] filter 50′ can be deployed out the distal end of the catheter. In particular, the filter 50′ may be urged out of the distal end of the catheter, e.g., by holding the catheter C still and urging the mandrel 20 distally or by holding the mandrel 20 stationary and withdrawing the catheter C proximally.
  • Upon exiting the distal end of the catheter C, the [0048] flexible body 52 will resiliently expand radially outwardly, desirably until it engages the wall of the vessel V or, less desirably, is positioned adjacent to the vessel wall. (Such a configuration is shown in FIG. 5.) This will help ensure that all fluid passing along the vessel V will have to pass through the filter body 52′.
  • A substantial portion (ideally, all or at least a vast majority) of the body fluid in the vessel should pass through the proximally oriented opening [0049] 56 in the filter body. Since the opening is fairly large, it is anticipated that any particulate material entrained in the body fluid travelling through the vessel will enter the interior of the filter through the opening 56. The pores in the distal length 53 of the filter body are significantly smaller, though, so most oversized particles will be trapped within the enclosure of the filter body. FIG. 6 schematically depicts such a situation, with a number of individual particles P being shown trapped within the filter body. If the filter 50 or 50′ is to be used in a vascular procedure, the pores should be large enough to permit red blood cells to pass therethrough, but small enough to trap thrombi or emboli above a certain predetermined size.
  • A wide variety of vascular filters are known in the art and thee with which such filters can be deployed varies. One of the primary distinguishing characteristics between these various filter designs is the ease with which the filters can be withdrawn from or repositioned within the patient's body. For example, most commercially available vena cava filters are provided with sharp barbs or other structures which firmly seat the devices in a wall of the vessel, but which effectively preclude retraction of the device. Temporary filters avoid such tenacious attachments to the vessel wall, permitting them to be retracted or moved after initial deployment. As noted above, though, one of the primary difficulties encountered in using such temporary filters is the risk of dumping the captured particulate material back into the vessel from which it was filtered. Many designs require that the physician first aspirate the particulate material or, in the case of thrombi captured in vascular procedures, use drugs which help break down the particles to clinically acceptable sizes. [0050]
  • International Publication No. WO 96/01591, mentioned previously, provides a particularly useful filter. This filter, which may be generally dome-shaped and have a proximally-facing lip, enables a physician to close the filter prior to retraction, keeping the captured particles within the filter during removal or repositioning. Unfortunately, this design is mechanically complex. In one embodiment disclosed therein, the filter is provided with a drawstring which can be used to draw the proximal edge of the filter down toward the wire on which it is carried, minimizing the risk of losing the particles. A second design proposed in this reference employs a separately deployable cover which can be brought into sealing engagement with the filter. While this may further reduce the risk of dumping particles back into the vessel, the increased mechanical complexity makes it difficult to provide a highly reliable, cost-effective device. [0051]
  • The present invention provides an elegant solution to these difficulties which minimizes mechanical complexity and promises to provide very effective containment of filtered particles. FIG. 7 shows the [0052] filter 50′ of FIGS. 4-6 partially retracted into the catheter C. If the filter is being used for only a short period of time, the catheter C may be the same catheter used to initially deploy the filter in the vessel. If the filter is to be left in place for a longer period of time, though, it may be preferred to remove the deployment catheter (FIG. 4) from the patient's body and later introduce a separate retrieval catheter by advancing the retrieval catheter along the mandrel 20.
  • The lumen of the retrieval catheter C in FIG. 7 has a diameter smaller than the maximum cross-sectional dimension of the body's expanded configuration. The lumen is larger than the narrow proximal end of the [0053] filter body 52′ adjacent the proximal slider 65′, though, and the illustrated filter body is spaced from the vessel wall about its entire periphery. As a consequence, the distal tip of the catheter can be positioned between the proximal end of the body 52′ and the wall of the vessel V before the catheter engages the body of the filter adjacent the slider. This can be done by holding the catheter in place and withdrawing the mandrel proximally, by holding the mandrel stationary and moving the catheter distally, or moving both the catheter and the mandrel.
  • Once the proximal end of the [0054] body 52′ is introduced into the catheter's lumen, the rest of the body can be drawn into the lumen of the catheter. Again, the body can be drawn into the catheter by advancing the catheter distally or retracing the filter proximally. At some point, the wall of the catheter C will engage the larger diameter body 52. Ideally, the lumen of the catheter is notably smaller than the deployed diameter of the filter body. As shown in FIG. 7, in this case the walls of the catheter will exert a biasing force to urge the body toward the radially reduced configuration in which it was initially deployed (FIG. 4).
  • Perhaps more importantly, though, the internal surface of the catheter engages the body of the filter distally of the filter's proximally oriented [0055] opening 56. While the opening may still be open to the lumen of the catheter, the engagement between the filer body and the catheter wall distally of the opening effectively creates a particulate seal therebetween. As a consequence, simply by advancing the catheter C with respect to the filter 50′, one can seal within the combined catheter and filter all of the captured particles above the predetermined minimum size. This combination can then be moved as a unit either to remove it from or reposition it within the patient's body with minimal risk of losing any of the captured particles.
  • If the filter is to be completely withdrawn from the vessel, it is preferred that the [0056] filter body 52′ be completely withdrawn into the lumen of the catheter (as shown in FIG. 8) rather than leaving a distal section of the filter extending out of the catheter (as shown in FIG. 7). This will reduce friction against the vessel wall, making withdrawal easier and reducing trauma to the intima of the vessel.
  • While a preferred embodiment of the present invention has been described, it should be understood that various changes, adaptations and modifications may be made therein without departing from the spirit of the invention and the scope of the appended claims. [0057]

Claims (22)

What is claimed is:
1. A method of deploying a medical filter within a channel in a patient's body, the method comprising:
a) providing a filter having a radially expandable body having proximal and distal ends and defining an enclosure, the body having a distal length and a proximal length which has an opening therein; and a retrieval catheter having a lumen with a diameter less than a maximum dimension of the body's expanded configuration;
b) urging the filter along a length of the channel with the filter body in a radially reduced configuration;
c) radially expanding the body to its expanded configuration such that it substantially fills the lumen of the vessel and the opening in the body is oriented proximally;
d) permitting body fluid to enter the enclosure through the proximally oriented opening and pass distally through the distal length of the body, the distal length of the body filtering from the body fluid particulate material entrained therein; and
e) drawing the proximal length of the body within the lumen of the retrieval catheter, thereby effectively closing the proximally oriented opening within the catheter to retain said particulate material within the enclosure.
2. The method of claim 1 wherein the proximal length of the filter's body tapers proximally to a narrow proximal end which is smaller than the lumen of the catheter, the step of drawing the proximal length within the catheter comprising receiving a narrow proximal end of the body in the lumen of the catheter then retracting the filter until the internal surface of the catheter engages the body of the filter distally of the opening to effectively create a particulate seal therebetween.
3. The method of claim 2 wherein the narrow proximal end of the body is spaced from a wall of the vessel when the filter is expanded into its expanded configuration.
4. The method of claim 3 wherein a wall of the catheter is positioned between the narrow proximal end of the body and the wall of the vessel as the proximal length of the body is drawn into the lumen of the catheter.
5. The method of claim 1 wherein a wall of the catheter urges the filter's body radially inwardly toward said radially reduced configuration as the body is drawn into the lumen thereof.
6. The method of claim 1 wherein the filter is urged along the channel in said radially reduced configuration within a deployment catheter.
7. The method of claim 6 wherein the same catheter is used as both the deployment catheter and the retrieval catheter.
8. The method of claim 6 wherein the deployment catheter's wall constrains the filter body in said radially reduced configuration when the body is received in the lumen thereof, body being radially expanded by deploying the filter out of the distal end of the catheter, whereupon the body resiliently expands radially outwardly upon removal of the constraint.
9. The method of claim 1 wherein the retrieval catheter is held substantially stationary as the proximal length of the filter's body is drawn therewithin.
10. The method of claim 1 wherein the proximal length of the filter's body is drawn into the catheter's lumen by holding the body substantially stationary and advancing the catheter distally over the proximal length thereof.
11. The method of claim 1 wherein the filter is carried by a mandrel, the catheter being advanced along the mandrel prior to drawing the body of the filter into the lumen thereof.
12. A collapsible filter system comprising:
a) a mandrel having a distal end and a proximal end; and
b) a filter carried along the mandrel, the filter comprising a radially expandable body having a proximal end and a distal end, the body being formed of a porous, resilient fabric having pores therein through which a body fluid may pass, but which restrict passage therethrough of particulate material entrained in the body fluid;
c) a proximally oriented hole passing through the fabric along a proximal length of the filter's body, the hole being spaced distally of the proximal end of the body and being at least about ten times the size of said pores.
13. The medical filter of claim 12 wherein the proximal length of the body tapers toward the body's proximal end.
14. The medical filter of claim 12 wherein one of the proximal end and the distal end of the body is secured to the mandrel at a fixed location therealong while the other end of the body is slidably carried by the mandrel.
15. The medical filter of claim 12 wherein the proximal end of the body is secured to the mandrel at a fixed location therealong while the distal end of the body is slidably carried by the mandrel.
16. The medical filter of claim 12 wherein the mandrel includes a stop spaced proximally of its distal end and positioned between the proximal and distal ends of the body, a proximal length of the mandrel extending proximally of the stop and a distal length of the mandrel extending distally of the stop.
17. The medical filter of claim 16 wherein the proximal end of the body is slidably carried along the proximal length of the mandrel and the distal end of the body is slidably carried along the distal length of the mandrel, the proximal and distal ends being slidable along the mandrel independently of one another such that the distance between the proximal and distal ends can be varied to effect different configurations of the filter.
18. The medical filter of claim 12 wherein the proximal end of the body is affixed to the mandrel adjacent a distal end thereof.
19. The medical filter of claim 12 wherein the proximal length of the filter's body includes a plurality of proximally oriented holes through the fabric.
20. The medical filter of claim 12 wherein the filter body defines an enclosure for retaining particulate material therein, the mandrel extending through the enclosure.
21. The medical filter of claim 20 wherein the enclosure has a central axis, the mandrel being spaced radially outward from the central axis and extending closer to one side of the body than to an opposite side of the body.
22. A method of using the medical filter of claim 12 wherein the radially expandable body is placed in a radially reduced configuration for deployment; the body is radially expanded to an expanded configuration at a treatment site; and a retrieval sheath is urged distally with respect to the filter, the retrieval sheath receiving therewithin the proximal length of the filter's body while engaging a periphery of the body distally of the opening, thereby effectively closing the proximally oriented opening within the retrieval sheath.
US10/060,854 1999-09-21 2002-01-30 Temporary vascular filter Abandoned US20020133192A1 (en)

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US09/400,159 US6325815B1 (en) 1999-09-21 1999-09-21 Temporary vascular filter
US09/824,910 US20020032460A1 (en) 1999-09-21 2001-04-03 Temporary vascular filter
US10/060,854 US20020133192A1 (en) 1999-09-21 2002-01-30 Temporary vascular filter

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US09/824,910 Abandoned US20020032460A1 (en) 1999-09-21 2001-04-03 Temporary vascular filter
US10/060,854 Abandoned US20020133192A1 (en) 1999-09-21 2002-01-30 Temporary vascular filter
US10/682,696 Active 2028-08-30 US8562637B2 (en) 1999-09-21 2003-10-09 Temporary vascular filter
US11/517,222 Abandoned US20070005105A1 (en) 1999-09-21 2006-09-07 Temporary vascular filter
US11/842,316 Abandoned US20080045998A1 (en) 1999-09-21 2007-08-21 Temporary vascular filter
US12/712,774 Abandoned US20100152768A1 (en) 1999-09-21 2010-02-25 Temporary vascular filter
US13/270,794 Expired - Fee Related US9039727B2 (en) 1999-09-21 2011-10-11 Temporary vascular filter

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US11/842,316 Abandoned US20080045998A1 (en) 1999-09-21 2007-08-21 Temporary vascular filter
US12/712,774 Abandoned US20100152768A1 (en) 1999-09-21 2010-02-25 Temporary vascular filter
US13/270,794 Expired - Fee Related US9039727B2 (en) 1999-09-21 2011-10-11 Temporary vascular filter

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Cited By (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080119889A1 (en) * 1999-08-27 2008-05-22 Ev3 Inc. Slideable vascular filter
US20090052804A1 (en) * 2007-08-22 2009-02-26 Prospect Technologies, Inc. Method process and apparatus for automated document scanning and management system
US7670355B2 (en) 1994-07-08 2010-03-02 Ev3 Inc. Method and device for filtering body fluid
US7766934B2 (en) 2005-07-12 2010-08-03 Cook Incorporated Embolic protection device with an integral basket and bag
US7771452B2 (en) 2005-07-12 2010-08-10 Cook Incorporated Embolic protection device with a filter bag that disengages from a basket
US7850708B2 (en) 2005-06-20 2010-12-14 Cook Incorporated Embolic protection device having a reticulated body with staggered struts
US7942893B2 (en) * 2001-02-28 2011-05-17 Boston Scientific Scimed, Inc. Filter retrieval catheter
US20110130784A1 (en) * 2002-07-12 2011-06-02 Ev3 Inc. Catheter with occluding cuff
US8052640B2 (en) 2006-02-01 2011-11-08 The Cleveland Clinic Foundation Method and apparatus for increasing blood flow through an obstructed blood vessel
US8083762B2 (en) 2002-03-08 2011-12-27 Tyco Healthcare Group Lp Distal protection devices having controllable wire motion
US8109962B2 (en) 2005-06-20 2012-02-07 Cook Medical Technologies Llc Retrievable device having a reticulation portion with staggered struts
US8152831B2 (en) 2005-11-17 2012-04-10 Cook Medical Technologies Llc Foam embolic protection device
US8182508B2 (en) 2005-10-04 2012-05-22 Cook Medical Technologies Llc Embolic protection device
US8187298B2 (en) 2005-08-04 2012-05-29 Cook Medical Technologies Llc Embolic protection device having inflatable frame
US8216269B2 (en) 2005-11-02 2012-07-10 Cook Medical Technologies Llc Embolic protection device having reduced profile
US8221446B2 (en) 2005-03-15 2012-07-17 Cook Medical Technologies Embolic protection device
US8252018B2 (en) 2007-09-14 2012-08-28 Cook Medical Technologies Llc Helical embolic protection device
US8252017B2 (en) 2005-10-18 2012-08-28 Cook Medical Technologies Llc Invertible filter for embolic protection
US8377092B2 (en) 2005-09-16 2013-02-19 Cook Medical Technologies Llc Embolic protection device
US8388644B2 (en) 2008-12-29 2013-03-05 Cook Medical Technologies Llc Embolic protection device and method of use
US8419748B2 (en) 2007-09-14 2013-04-16 Cook Medical Technologies Llc Helical thrombus removal device
US8632562B2 (en) 2005-10-03 2014-01-21 Cook Medical Technologies Llc Embolic protection device
US8795315B2 (en) 2004-10-06 2014-08-05 Cook Medical Technologies Llc Emboli capturing device having a coil and method for capturing emboli
US8945169B2 (en) 2005-03-15 2015-02-03 Cook Medical Technologies Llc Embolic protection device
US9138307B2 (en) 2007-09-14 2015-09-22 Cook Medical Technologies Llc Expandable device for treatment of a stricture in a body vessel
US9468514B2 (en) 2002-03-12 2016-10-18 Covidien Lp Everted filter device
US9901434B2 (en) 2007-02-27 2018-02-27 Cook Medical Technologies Llc Embolic protection device including a Z-stent waist band
US9907639B2 (en) 2006-09-19 2018-03-06 Cook Medical Technologies Llc Apparatus and methods for in situ embolic protection

Families Citing this family (232)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE382309T1 (en) 1997-11-07 2008-01-15 Salviac Ltd EMBOLIC PROTECTION DEVICE
US7491216B2 (en) 1997-11-07 2009-02-17 Salviac Limited Filter element with retractable guidewire tip
AU751056B2 (en) * 1998-04-02 2002-08-08 Salviac Limited Delivery catheter
US7314477B1 (en) 1998-09-25 2008-01-01 C.R. Bard Inc. Removable embolus blood clot filter and filter delivery unit
US6896690B1 (en) 2000-01-27 2005-05-24 Viacor, Inc. Cardiac valve procedure methods and devices
US6171327B1 (en) 1999-02-24 2001-01-09 Scimed Life Systems, Inc. Intravascular filter and method
US6964672B2 (en) 1999-05-07 2005-11-15 Salviac Limited Support frame for an embolic protection device
US7037320B2 (en) * 2001-12-21 2006-05-02 Salviac Limited Support frame for an embolic protection device
AU4606400A (en) 1999-05-07 2000-11-21 Salviac Limited Improved filter element for embolic protection device
WO2000067666A1 (en) * 1999-05-07 2000-11-16 Salviac Limited Improved filter element for embolic protection device
US6918921B2 (en) 1999-05-07 2005-07-19 Salviac Limited Support frame for an embolic protection device
US20030150821A1 (en) * 1999-07-16 2003-08-14 Bates Mark C. Emboli filtration system and methods of use
US6544279B1 (en) 2000-08-09 2003-04-08 Incept, Llc Vascular device for emboli, thrombus and foreign body removal and methods of use
US6346116B1 (en) * 1999-08-03 2002-02-12 Medtronic Ave, Inc. Distal protection device
US6146404A (en) * 1999-09-03 2000-11-14 Scimed Life Systems, Inc. Removable thrombus filter
US6325815B1 (en) * 1999-09-21 2001-12-04 Microvena Corporation Temporary vascular filter
US6217589B1 (en) 1999-10-27 2001-04-17 Scimed Life Systems, Inc. Retrieval device made of precursor alloy cable and method of manufacturing
US6371971B1 (en) * 1999-11-15 2002-04-16 Scimed Life Systems, Inc. Guidewire filter and methods of use
US6660021B1 (en) 1999-12-23 2003-12-09 Advanced Cardiovascular Systems, Inc. Intravascular device and system
US6402771B1 (en) 1999-12-23 2002-06-11 Guidant Endovascular Solutions Snare
US6575997B1 (en) 1999-12-23 2003-06-10 Endovascular Technologies, Inc. Embolic basket
US7918820B2 (en) 1999-12-30 2011-04-05 Advanced Cardiovascular Systems, Inc. Device for, and method of, blocking emboli in vessels such as blood arteries
US6695813B1 (en) 1999-12-30 2004-02-24 Advanced Cardiovascular Systems, Inc. Embolic protection devices
US7749245B2 (en) 2000-01-27 2010-07-06 Medtronic, Inc. Cardiac valve procedure methods and devices
GB2369575A (en) * 2000-04-20 2002-06-05 Salviac Ltd An embolic protection system
US6602271B2 (en) 2000-05-24 2003-08-05 Medtronic Ave, Inc. Collapsible blood filter with optimal braid geometry
US6565591B2 (en) 2000-06-23 2003-05-20 Salviac Limited Medical device
GB2368529B (en) * 2000-06-23 2004-05-12 Salviac Ltd Improved filter element for embolic protection device
US6964670B1 (en) 2000-07-13 2005-11-15 Advanced Cardiovascular Systems, Inc. Embolic protection guide wire
US6656202B2 (en) * 2000-07-14 2003-12-02 Advanced Cardiovascular Systems, Inc. Embolic protection systems
US6740061B1 (en) * 2000-07-28 2004-05-25 Ev3 Inc. Distal protection device
US6506203B1 (en) 2000-12-19 2003-01-14 Advanced Cardiovascular Systems, Inc. Low profile sheathless embolic protection system
US6610077B1 (en) * 2001-01-23 2003-08-26 Endovascular Technologies, Inc. Expandable emboli filter and thrombectomy device
US6506205B2 (en) 2001-02-20 2003-01-14 Mark Goldberg Blood clot filtering system
US6911036B2 (en) * 2001-04-03 2005-06-28 Medtronic Vascular, Inc. Guidewire apparatus for temporary distal embolic protection
US6706055B2 (en) 2001-04-03 2004-03-16 Medtronic Ave Inc. Guidewire apparatus for temporary distal embolic protection
US7338514B2 (en) 2001-06-01 2008-03-04 St. Jude Medical, Cardiology Division, Inc. Closure devices, related delivery methods and tools, and related methods of use
US20020188314A1 (en) * 2001-06-07 2002-12-12 Microvena Corporation Radiopaque distal embolic protection device
US6599307B1 (en) 2001-06-29 2003-07-29 Advanced Cardiovascular Systems, Inc. Filter device for embolic protection systems
US7338510B2 (en) 2001-06-29 2008-03-04 Advanced Cardiovascular Systems, Inc. Variable thickness embolic filtering devices and method of manufacturing the same
US6638294B1 (en) 2001-08-30 2003-10-28 Advanced Cardiovascular Systems, Inc. Self furling umbrella frame for carotid filter
US6592606B2 (en) 2001-08-31 2003-07-15 Advanced Cardiovascular Systems, Inc. Hinged short cage for an embolic protection device
US8262689B2 (en) 2001-09-28 2012-09-11 Advanced Cardiovascular Systems, Inc. Embolic filtering devices
US6887257B2 (en) 2001-10-19 2005-05-03 Incept Llc Vascular embolic filter exchange devices and methods of use thereof
US7749243B2 (en) * 2001-10-19 2010-07-06 Boston Scientific Scimed, Inc. Embolus extractor
US20050021075A1 (en) * 2002-12-30 2005-01-27 Bonnette Michael J. Guidewire having deployable sheathless protective filter
US6837898B2 (en) 2001-11-30 2005-01-04 Advanced Cardiovascular Systems, Inc. Intraluminal delivery system for an attachable treatment device
US7241304B2 (en) * 2001-12-21 2007-07-10 Advanced Cardiovascular Systems, Inc. Flexible and conformable embolic filtering devices
US9204956B2 (en) 2002-02-20 2015-12-08 C. R. Bard, Inc. IVC filter with translating hooks
US7144408B2 (en) * 2002-03-05 2006-12-05 Salviac Limited Embolic protection system
US7063707B2 (en) * 2002-03-06 2006-06-20 Scimed Life Systems, Inc. Medical retrieval device
US7192434B2 (en) * 2002-03-08 2007-03-20 Ev3 Inc. Vascular protection devices and methods of use
US20030187495A1 (en) 2002-04-01 2003-10-02 Cully Edward H. Endoluminal devices, embolic filters, methods of manufacture and use
US7976564B2 (en) 2002-05-06 2011-07-12 St. Jude Medical, Cardiology Division, Inc. PFO closure devices and related methods of use
AU2003234601A1 (en) 2002-05-14 2003-12-02 Bacchus Vascular, Inc. Apparatus and method for removing occlusive material within blood vessels
US7001406B2 (en) * 2002-05-23 2006-02-21 Scimed Life Systems Inc. Cartridge embolic protection filter and methods of use
US7717934B2 (en) 2002-06-14 2010-05-18 Ev3 Inc. Rapid exchange catheters usable with embolic protection devices
US7232452B2 (en) * 2002-07-12 2007-06-19 Ev3 Inc. Device to create proximal stasis
DE10233085B4 (en) 2002-07-19 2014-02-20 Dendron Gmbh Stent with guide wire
US8425549B2 (en) 2002-07-23 2013-04-23 Reverse Medical Corporation Systems and methods for removing obstructive matter from body lumens and treating vascular defects
US8444666B2 (en) 2002-09-12 2013-05-21 Cook Medical Technologies Llc Retrievable filter
US7331973B2 (en) 2002-09-30 2008-02-19 Avdanced Cardiovascular Systems, Inc. Guide wire with embolic filtering attachment
US7252675B2 (en) 2002-09-30 2007-08-07 Advanced Cardiovascular, Inc. Embolic filtering devices
US8468678B2 (en) 2002-10-02 2013-06-25 Boston Scientific Scimed, Inc. Expandable retrieval device
US7998163B2 (en) 2002-10-03 2011-08-16 Boston Scientific Scimed, Inc. Expandable retrieval device
US20040093012A1 (en) 2002-10-17 2004-05-13 Cully Edward H. Embolic filter frame having looped support strut elements
US20040088000A1 (en) 2002-10-31 2004-05-06 Muller Paul F. Single-wire expandable cages for embolic filtering devices
US7128752B2 (en) * 2002-12-23 2006-10-31 Syntheon, Llc Emboli and thrombi filter device and method of using the same
US7323001B2 (en) * 2003-01-30 2008-01-29 Ev3 Inc. Embolic filters with controlled pore size
US7220271B2 (en) 2003-01-30 2007-05-22 Ev3 Inc. Embolic filters having multiple layers and controlled pore size
US20040153119A1 (en) 2003-01-30 2004-08-05 Kusleika Richard S. Embolic filters with a distal loop or no loop
US7763045B2 (en) 2003-02-11 2010-07-27 Cook Incorporated Removable vena cava filter
US6878291B2 (en) 2003-02-24 2005-04-12 Scimed Life Systems, Inc. Flexible tube for cartridge filter
US7740644B2 (en) 2003-02-24 2010-06-22 Boston Scientific Scimed, Inc. Embolic protection filtering device that can be adapted to be advanced over a guidewire
US8591540B2 (en) 2003-02-27 2013-11-26 Abbott Cardiovascular Systems Inc. Embolic filtering devices
US20040193208A1 (en) * 2003-03-27 2004-09-30 Scimed Life Systems, Inc. Radiopaque embolic protection filter membrane
EP1608295B1 (en) 2003-03-28 2017-05-03 Covidien LP Double ended intravascular medical device
US8372112B2 (en) 2003-04-11 2013-02-12 St. Jude Medical, Cardiology Division, Inc. Closure devices, related delivery methods, and related methods of use
US20040267306A1 (en) 2003-04-11 2004-12-30 Velocimed, L.L.C. Closure devices, related delivery methods, and related methods of use
US7122043B2 (en) 2003-05-19 2006-10-17 Stout Medical Group, L.P. Tissue distention device and related methods for therapeutic intervention
US9301829B2 (en) 2003-07-30 2016-04-05 Boston Scientific Scimed, Inc. Embolic protection aspirator
US7056286B2 (en) 2003-11-12 2006-06-06 Adrian Ravenscroft Medical device anchor and delivery system
US7892251B1 (en) 2003-11-12 2011-02-22 Advanced Cardiovascular Systems, Inc. Component for delivering and locking a medical device to a guide wire
US7716801B2 (en) * 2003-11-24 2010-05-18 Medtronic Vascular, Inc. Low-profile distal protection device
US7678129B1 (en) 2004-03-19 2010-03-16 Advanced Cardiovascular Systems, Inc. Locking component for an embolic filter assembly
WO2005094283A2 (en) 2004-03-25 2005-10-13 Hauser David L Vascular filter device
US20050234501A1 (en) * 2004-04-15 2005-10-20 Barone David D Braided intraluminal filter
DE602005017599D1 (en) 2004-04-16 2009-12-24 Cook William Europ REMOVABLE VENA CAVA FILTER WITH ANCHORED HOOKS LAYING DOWN IN FOLDED CONDITION
WO2005102213A1 (en) 2004-04-16 2005-11-03 Cook, Inc. Removable vena cava filter having primary struts for enhanced retrieval and delivery
AU2005235301B2 (en) 2004-04-16 2010-07-22 Cook, Inc. Removable vena cava filter for reduced trauma in collapsed configuration
EP1737385B1 (en) 2004-04-16 2010-12-15 Cook Incorporated Removable vena cava filter with anchoring feature for reduced trauma
US20050251198A1 (en) * 2004-05-06 2005-11-10 Scimed Life Systems, Inc. Intravascular filter membrane and method of forming
US7704267B2 (en) 2004-08-04 2010-04-27 C. R. Bard, Inc. Non-entangling vena cava filter
CA2580209C (en) * 2004-09-17 2013-11-12 Nitinol Development Corporation Shape memory thin film embolic protection device with frame
US8167901B2 (en) 2004-09-27 2012-05-01 Cook Medical Technologies Llc Removable vena cava filter comprising struts having axial bends
US7976517B2 (en) * 2004-09-30 2011-07-12 Codman & Shurtleff, Inc. Fluid management flow implants of improved occlusion resistance
US7794473B2 (en) 2004-11-12 2010-09-14 C.R. Bard, Inc. Filter delivery system
US9707071B2 (en) 2004-11-24 2017-07-18 Contego Medical Llc Percutaneous transluminal angioplasty device with integral embolic filter
US8029529B1 (en) 2005-01-19 2011-10-04 C. R. Bard, Inc. Retrievable filter
US8267954B2 (en) * 2005-02-04 2012-09-18 C. R. Bard, Inc. Vascular filter with sensing capability
US20060184194A1 (en) * 2005-02-15 2006-08-17 Cook Incorporated Embolic protection device
US7993362B2 (en) * 2005-02-16 2011-08-09 Boston Scientific Scimed, Inc. Filter with positioning and retrieval devices and methods
ATE539789T1 (en) 2005-02-18 2012-01-15 Tyco Healthcare QUICKLY REPLACEABLE CATHETER
US9259305B2 (en) 2005-03-31 2016-02-16 Abbott Cardiovascular Systems Inc. Guide wire locking mechanism for rapid exchange and other catheter systems
US8025668B2 (en) * 2005-04-28 2011-09-27 C. R. Bard, Inc. Medical device removal system
US7967838B2 (en) 2005-05-12 2011-06-28 C. R. Bard, Inc. Removable embolus blood clot filter
EP1912696A1 (en) 2005-08-09 2008-04-23 C.R.Bard, Inc. Embolus blood clot filter and delivery system
US20070100372A1 (en) * 2005-11-02 2007-05-03 Cook Incorporated Embolic protection device having a filter
CA2940038C (en) 2005-11-18 2018-08-28 C.R. Bard, Inc. Vena cava filter with filament
WO2007126931A2 (en) * 2006-03-31 2007-11-08 Ev3 Inc. Embolic protection devices having radiopaque markers
US7846175B2 (en) * 2006-04-03 2010-12-07 Medrad, Inc. Guidewire and collapsable filter system
WO2007133366A2 (en) * 2006-05-02 2007-11-22 C. R. Bard, Inc. Vena cava filter formed from a sheet
US9326842B2 (en) 2006-06-05 2016-05-03 C. R . Bard, Inc. Embolus blood clot filter utilizable with a single delivery system or a single retrieval system in one of a femoral or jugular access
US20080234722A1 (en) * 2006-06-14 2008-09-25 Possis Medical, Inc. Inferior vena cava filter on guidewire
JP4483835B2 (en) * 2006-08-01 2010-06-16 ニプロ株式会社 Thrombus capture member recovery sheath and thrombus capture catheter
US9149609B2 (en) * 2006-10-16 2015-10-06 Embolitech, Llc Catheter for removal of an organized embolic thrombus
US20080269774A1 (en) 2006-10-26 2008-10-30 Chestnut Medical Technologies, Inc. Intracorporeal Grasping Device
WO2008086511A2 (en) * 2007-01-11 2008-07-17 Ev3 Inc. Convertible embolic protection devices and methods of use
WO2008094827A1 (en) 2007-02-02 2008-08-07 Ev3 Inc. Embolic protection devices having short landing zones
US8052639B2 (en) * 2007-04-10 2011-11-08 Wilson David B Clampless anastomotic device
US8864789B2 (en) * 2007-04-27 2014-10-21 DePuy Synthes Products, LLC Interventional medical device system having a spiral section and radiopaque marker and method of making the same
US8197442B2 (en) * 2007-04-27 2012-06-12 Codman & Shurtleff, Inc. Interventional medical device system having a slotted section and radiopaque marker and method of making the same
US8216209B2 (en) 2007-05-31 2012-07-10 Abbott Cardiovascular Systems Inc. Method and apparatus for delivering an agent to a kidney
EP2157937B1 (en) 2007-06-04 2017-03-22 Sequent Medical, Inc. Devices for treatment of vascular defects
US7867273B2 (en) 2007-06-27 2011-01-11 Abbott Laboratories Endoprostheses for peripheral arteries and other body vessels
US8585713B2 (en) 2007-10-17 2013-11-19 Covidien Lp Expandable tip assembly for thrombus management
US10123803B2 (en) 2007-10-17 2018-11-13 Covidien Lp Methods of managing neurovascular obstructions
US8545514B2 (en) 2008-04-11 2013-10-01 Covidien Lp Monorail neuro-microcatheter for delivery of medical devices to treat stroke, processes and products thereby
US8926680B2 (en) 2007-11-12 2015-01-06 Covidien Lp Aneurysm neck bridging processes with revascularization systems methods and products thereby
US9198687B2 (en) 2007-10-17 2015-12-01 Covidien Lp Acute stroke revascularization/recanalization systems processes and products thereby
US8066757B2 (en) 2007-10-17 2011-11-29 Mindframe, Inc. Blood flow restoration and thrombus management methods
US9220522B2 (en) 2007-10-17 2015-12-29 Covidien Lp Embolus removal systems with baskets
US11337714B2 (en) 2007-10-17 2022-05-24 Covidien Lp Restoring blood flow and clot removal during acute ischemic stroke
US8088140B2 (en) 2008-05-19 2012-01-03 Mindframe, Inc. Blood flow restorative and embolus removal methods
WO2009055782A1 (en) 2007-10-26 2009-04-30 Possis Medical, Inc. Intravascular guidewire filter system for pulmonary embolism protection and embolism removal or maceration
US8246672B2 (en) 2007-12-27 2012-08-21 Cook Medical Technologies Llc Endovascular graft with separately positionable and removable frame units
ES2647310T3 (en) 2008-02-22 2017-12-20 Covidien Lp Device for flow restoration
US20110264132A1 (en) * 2008-04-04 2011-10-27 Reverse Medical Corporation Multi-utilitarian microcatheter system and method of use
US9597087B2 (en) 2008-05-02 2017-03-21 Sequent Medical, Inc. Filamentary devices for treatment of vascular defects
US20090292307A1 (en) * 2008-05-22 2009-11-26 Nasser Razack Mechanical embolectomy device and method
US9402707B2 (en) 2008-07-22 2016-08-02 Neuravi Limited Clot capture systems and associated methods
US20100087850A1 (en) * 2008-10-03 2010-04-08 Nasser Razack Mechanical Embolectomy Device and Method
US20100114135A1 (en) * 2008-10-31 2010-05-06 Scott Wilson Devices and methods for temporarily opening a blood vessel
US8246648B2 (en) 2008-11-10 2012-08-21 Cook Medical Technologies Llc Removable vena cava filter with improved leg
US20100137899A1 (en) * 2008-12-02 2010-06-03 Nasser Razack Mechanical Embolectomy Device and Method
WO2011034718A2 (en) 2009-09-21 2011-03-24 Claret Medical, Inc. Intravascular blood filters and methods of use
ES2516066T3 (en) 2009-01-16 2014-10-30 Claret Medical, Inc. Intravascular blood filter
US20170202657A1 (en) 2009-01-16 2017-07-20 Claret Medical, Inc. Intravascular blood filters and methods of use
US9326843B2 (en) 2009-01-16 2016-05-03 Claret Medical, Inc. Intravascular blood filters and methods of use
EP2391303A4 (en) 2009-01-29 2020-09-09 Boston Scientific Scimed, Inc. Illuminated intravascular blood filter
US20100286722A1 (en) * 2009-05-11 2010-11-11 Intersect Partners, Llc Temporary venous filter system
US8974489B2 (en) 2009-07-27 2015-03-10 Claret Medical, Inc. Dual endovascular filter and methods of use
MX2012001288A (en) 2009-07-29 2012-06-19 Bard Inc C R Tubular filter.
US20110054504A1 (en) * 2009-08-31 2011-03-03 Boston Scientific Scimed, Inc. Recanalization device with expandable cage
US10092427B2 (en) 2009-11-04 2018-10-09 Confluent Medical Technologies, Inc. Alternating circumferential bridge stent design and methods for use thereof
US9649211B2 (en) 2009-11-04 2017-05-16 Confluent Medical Technologies, Inc. Alternating circumferential bridge stent design and methods for use thereof
US20110152993A1 (en) 2009-11-05 2011-06-23 Sequent Medical Inc. Multiple layer filamentary devices or treatment of vascular defects
WO2011106426A1 (en) 2010-02-23 2011-09-01 Maria Aboytes Devices and methods for vascular recanalization
US9039749B2 (en) 2010-10-01 2015-05-26 Covidien Lp Methods and apparatuses for flow restoration and implanting members in the human body
WO2012052982A1 (en) 2010-10-22 2012-04-26 Neuravi Limited Clot engagement and removal system
AU2010364209B2 (en) * 2010-11-15 2016-05-19 Endovascular Development AB An assembly with a guide wire and a fixator for attaching to a blood vessel
US9345565B2 (en) 2010-12-30 2016-05-24 Claret Medical, Inc. Steerable dual filter cerebral protection system
US10022212B2 (en) 2011-01-13 2018-07-17 Cook Medical Technologies Llc Temporary venous filter with anti-coagulant delivery method
WO2012120490A2 (en) 2011-03-09 2012-09-13 Neuravi Limited A clot retrieval device for removing occlusive clot from a blood vessel
US11259824B2 (en) 2011-03-09 2022-03-01 Neuravi Limited Clot retrieval device for removing occlusive clot from a blood vessel
WO2013071173A1 (en) * 2011-11-11 2013-05-16 Dacuycuy Nathan John Devices for removing vessel occlusions
EP2802374B1 (en) * 2012-01-09 2016-11-30 BiO2 Medical, Inc. Connector hub apparatus for catheter and methods of use
US9308007B2 (en) 2012-08-14 2016-04-12 W. L. Gore & Associates, Inc. Devices and systems for thrombus treatment
US9572960B2 (en) 2012-10-01 2017-02-21 C.R. Bard, Inc. Balloon catheter having multiple inflation lumens and related methods
US9433429B2 (en) 2013-03-14 2016-09-06 Neuravi Limited Clot retrieval devices
CN105208950A (en) 2013-03-14 2015-12-30 尼尔拉维有限公司 A clot retrieval device for removing occlusive clot from a blood vessel
WO2014140092A2 (en) 2013-03-14 2014-09-18 Neuravi Limited Devices and methods for removal of acute blockages from blood vessels
US8715315B1 (en) 2013-03-15 2014-05-06 Insera Therapeutics, Inc. Vascular treatment systems
US8679150B1 (en) 2013-03-15 2014-03-25 Insera Therapeutics, Inc. Shape-set textile structure based mechanical thrombectomy methods
WO2014150288A2 (en) 2013-03-15 2014-09-25 Insera Therapeutics, Inc. Vascular treatment devices and methods
US8715314B1 (en) 2013-03-15 2014-05-06 Insera Therapeutics, Inc. Vascular treatment measurement methods
EP2996630B1 (en) * 2013-05-14 2022-04-06 Transverse Medical, Inc. Catheter-based apparatuses
WO2014201043A1 (en) 2013-06-10 2014-12-18 Myla Subbarao V Methods and devices for embolic protection
US9955976B2 (en) 2013-08-16 2018-05-01 Sequent Medical, Inc. Filamentary devices for treatment of vascular defects
US9078658B2 (en) 2013-08-16 2015-07-14 Sequent Medical, Inc. Filamentary devices for treatment of vascular defects
US10076399B2 (en) 2013-09-13 2018-09-18 Covidien Lp Endovascular device engagement
US9629635B2 (en) 2014-04-14 2017-04-25 Sequent Medical, Inc. Devices for therapeutic vascular procedures
US20150297250A1 (en) * 2014-04-16 2015-10-22 Covidien Lp Systems and methods for catheter advancement
US10202714B2 (en) * 2014-10-30 2019-02-12 Federal-Mogul Powertrain Llc Braided textile sleeve with self-sustaining expanded and contracted states and method of construction thereof
US11253278B2 (en) 2014-11-26 2022-02-22 Neuravi Limited Clot retrieval system for removing occlusive clot from a blood vessel
US10617435B2 (en) 2014-11-26 2020-04-14 Neuravi Limited Clot retrieval device for removing clot from a blood vessel
CN106999196B (en) 2014-11-26 2020-07-28 尼尔拉维有限公司 Thrombus retrieval device for removing obstructive thrombus from blood vessel
US10182834B2 (en) 2015-01-08 2019-01-22 Cook Medical Technologies Llc Delivery of thrombolytic agent through actuation member of thrombus retrieval device
US10292805B2 (en) 2015-01-23 2019-05-21 Contego Medical, Llc Interventional device having an integrated embolic filter and associated methods
US9566144B2 (en) 2015-04-22 2017-02-14 Claret Medical, Inc. Vascular filters, deflectors, and methods
CN107690314B (en) * 2015-07-16 2020-06-09 珀弗娄医疗有限公司 Device and method for removing vessel occlusion
EP4272660A3 (en) 2015-07-24 2024-01-03 Ichor Vascular Inc. Embolectomy system
ES2770017T3 (en) * 2015-09-10 2020-06-30 Endovascular Dev Ab An extensible and recoverable endovascular element
US10478194B2 (en) * 2015-09-23 2019-11-19 Covidien Lp Occlusive devices
AU2016341439B2 (en) 2015-10-23 2021-07-08 Inari Medical, Inc. Intravascular treatment of vascular occlusion and associated devices, systems, and methods
FR3047406B1 (en) * 2016-02-09 2021-06-18 Antonino Machi THROMBECTOMY DEVICE
JP2017140230A (en) 2016-02-10 2017-08-17 テルモ株式会社 Medical device and treatment method
EP3416568A4 (en) 2016-02-16 2019-10-16 Insera Therapeutics, Inc. Aspiration devices and anchored flow diverting devices
JP2019062932A (en) 2016-02-23 2019-04-25 テルモ株式会社 Medical device and treatment method
US10357363B2 (en) * 2016-06-09 2019-07-23 Medtronic Vascular, Inc. Transcatheter valve delivery system with crimped prosthetic heart valve
CA3035706A1 (en) 2016-09-06 2018-03-15 Neuravi Limited A clot retrieval device for removing occlusive clot from a blood vessel
WO2018080590A1 (en) 2016-10-24 2018-05-03 Inari Medical Devices and methods for treating vascular occlusion
WO2018148239A1 (en) * 2017-02-07 2018-08-16 The Cleveland Clinic Foundation System, method, and apparatus for collecting emboli
CN110831545B (en) 2017-02-22 2022-06-07 波士顿科学国际有限公司 System and method for protecting cerebral blood vessels
US10595842B2 (en) * 2017-03-16 2020-03-24 William Joseph Drasler Expandable cardiac access catheter
US11000682B2 (en) 2017-09-06 2021-05-11 Inari Medical, Inc. Hemostasis valves and methods of use
CN111565673A (en) 2017-10-27 2020-08-21 波士顿科学医学有限公司 System and method for protecting cerebral blood vessels
US11229451B2 (en) 2017-12-13 2022-01-25 Eric Raul GUERRA Thrombectomy catheter and methods of use
US11134967B2 (en) 2017-12-13 2021-10-05 Eric Raul GUERRA Thrombectomy catheter and methods of use
EP3727192B1 (en) 2017-12-19 2023-03-08 Boston Scientific Scimed, Inc. System for protecting the cerebral vasculature
US11154314B2 (en) 2018-01-26 2021-10-26 Inari Medical, Inc. Single insertion delivery system for treating embolism and associated systems and methods
JP7137933B2 (en) * 2018-02-20 2022-09-15 テルモ株式会社 filter device
CN112334093A (en) 2018-04-26 2021-02-05 波士顿科学国际有限公司 System for protecting cerebral blood vessels
EP3836855A4 (en) 2018-08-13 2022-08-10 Inari Medical, Inc. System for treating embolism and associated devices and methods
JP2021535778A (en) 2018-08-21 2021-12-23 ボストン サイエンティフィック サイムド, インコーポレイテッドBoston Scientific Scimed, Inc. A system to protect the cerebrovascular system
US10842498B2 (en) 2018-09-13 2020-11-24 Neuravi Limited Systems and methods of restoring perfusion to a vessel
US11406416B2 (en) 2018-10-02 2022-08-09 Neuravi Limited Joint assembly for vasculature obstruction capture device
US11317921B2 (en) 2019-03-15 2022-05-03 Sequent Medical, Inc. Filamentary devices for treatment of vascular defects
JP2022525316A (en) 2019-03-15 2022-05-12 シークエント メディカル インコーポレイテッド Filamentous devices for the treatment of angiopathy
EP3908208A4 (en) 2019-03-15 2022-10-19 Sequent Medical, Inc. Filamentary devices having a flexible joint for treatment of vascular defects
US11523838B2 (en) 2019-06-12 2022-12-13 Covidien Lp Retrieval of material from corporeal lumens
EP4044938A4 (en) 2019-10-16 2023-11-15 Inari Medical, Inc. Systems, devices, and methods for treating vascular occlusions
US11712231B2 (en) 2019-10-29 2023-08-01 Neuravi Limited Proximal locking assembly design for dual stent mechanical thrombectomy device
US11517340B2 (en) 2019-12-03 2022-12-06 Neuravi Limited Stentriever devices for removing an occlusive clot from a vessel and methods thereof
US11730501B2 (en) 2020-04-17 2023-08-22 Neuravi Limited Floating clot retrieval device for removing clots from a blood vessel
US11871946B2 (en) 2020-04-17 2024-01-16 Neuravi Limited Clot retrieval device for removing clot from a blood vessel
US11717308B2 (en) 2020-04-17 2023-08-08 Neuravi Limited Clot retrieval device for removing heterogeneous clots from a blood vessel
US11737771B2 (en) 2020-06-18 2023-08-29 Neuravi Limited Dual channel thrombectomy device
US11439418B2 (en) 2020-06-23 2022-09-13 Neuravi Limited Clot retrieval device for removing clot from a blood vessel
US11395669B2 (en) 2020-06-23 2022-07-26 Neuravi Limited Clot retrieval device with flexible collapsible frame
US11864781B2 (en) 2020-09-23 2024-01-09 Neuravi Limited Rotating frame thrombectomy device
CN115844491B (en) * 2022-12-06 2023-05-16 杭州亿科医疗科技有限公司 Thrombolysis device with controllable retraction and expansion of thrombolysis net

Citations (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4619246A (en) * 1984-05-23 1986-10-28 William Cook, Europe A/S Collapsible filter basket
US4665906A (en) * 1983-10-14 1987-05-19 Raychem Corporation Medical devices incorporating sim alloy elements
US4873978A (en) * 1987-12-04 1989-10-17 Robert Ginsburg Device and method for emboli retrieval
US5067957A (en) * 1983-10-14 1991-11-26 Raychem Corporation Method of inserting medical devices incorporating SIM alloy elements
US5071407A (en) * 1990-04-12 1991-12-10 Schneider (U.S.A.) Inc. Radially expandable fixation member
US5108419A (en) * 1990-08-16 1992-04-28 Evi Corporation Endovascular filter and method for use thereof
US5160342A (en) * 1990-08-16 1992-11-03 Evi Corp. Endovascular filter and method for use thereof
US5171233A (en) * 1990-04-25 1992-12-15 Microvena Corporation Snare-type probe
US5190546A (en) * 1983-10-14 1993-03-02 Raychem Corporation Medical devices incorporating SIM alloy elements
US5192286A (en) * 1991-07-26 1993-03-09 Regents Of The University Of California Method and device for retrieving materials from body lumens
US5496277A (en) * 1990-04-12 1996-03-05 Schneider (Usa) Inc. Radially expandable body implantable device
US5695519A (en) * 1995-11-30 1997-12-09 American Biomed, Inc. Percutaneous filter for carotid angioplasty
US5814064A (en) * 1997-03-06 1998-09-29 Scimed Life Systems, Inc. Distal protection device
US5827324A (en) * 1997-03-06 1998-10-27 Scimed Life Systems, Inc. Distal protection device
US5910154A (en) * 1997-05-08 1999-06-08 Embol-X, Inc. Percutaneous catheter and guidewire having filter and medical device deployment
US6050972A (en) * 1996-05-20 2000-04-18 Percusurge, Inc. Guidewire inflation system
US6096053A (en) * 1996-05-03 2000-08-01 Scimed Life Systems, Inc. Medical retrieval basket
US6123715A (en) * 1994-07-08 2000-09-26 Amplatz; Curtis Method of forming medical devices; intravascular occlusion devices
US6129739A (en) * 1999-07-30 2000-10-10 Incept Llc Vascular device having one or more articulation regions and methods of use
US6171327B1 (en) * 1999-02-24 2001-01-09 Scimed Life Systems, Inc. Intravascular filter and method
US6179861B1 (en) * 1999-07-30 2001-01-30 Incept Llc Vascular device having one or more articulation regions and methods of use
US6179859B1 (en) * 1999-07-16 2001-01-30 Baff Llc Emboli filtration system and methods of use
US6214026B1 (en) * 1999-07-30 2001-04-10 Incept Llc Delivery system for a vascular device with articulation region
US6231588B1 (en) * 1998-08-04 2001-05-15 Percusurge, Inc. Low profile catheter for angioplasty and occlusion
US6245012B1 (en) * 1999-03-19 2001-06-12 Nmt Medical, Inc. Free standing filter
US6270477B1 (en) * 1996-05-20 2001-08-07 Percusurge, Inc. Catheter for emboli containment
US6287321B1 (en) * 1998-10-13 2001-09-11 Embol-X, Inc. Percutaneous filtration catheter for valve repair surgery
US6325815B1 (en) * 1999-09-21 2001-12-04 Microvena Corporation Temporary vascular filter
US6336934B1 (en) * 1997-11-07 2002-01-08 Salviac Limited Embolic protection device
US6371971B1 (en) * 1999-11-15 2002-04-16 Scimed Life Systems, Inc. Guidewire filter and methods of use

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2821048C2 (en) 1978-05-13 1980-07-17 Willy Ruesch Gmbh & Co Kg, 7053 Kernen Medical instrument
US4425908A (en) 1981-10-22 1984-01-17 Beth Israel Hospital Blood clot filter
US4926858A (en) 1984-05-30 1990-05-22 Devices For Vascular Intervention, Inc. Atherectomy device for severe occlusions
US4723549A (en) 1986-09-18 1988-02-09 Wholey Mark H Method and apparatus for dilating blood vessels
FR2624747A1 (en) * 1987-12-18 1989-06-23 Delsanti Gerard REMOVABLE ENDO-ARTERIAL DEVICES FOR REPAIRING ARTERIAL WALL DECOLLEMENTS
US4921484A (en) * 1988-07-25 1990-05-01 Cordis Corporation Mesh balloon catheter device
US5152777A (en) 1989-01-25 1992-10-06 Uresil Corporation Device and method for providing protection from emboli and preventing occulsion of blood vessels
US5041093A (en) 1990-01-31 1991-08-20 Boston Scientific Corp. Catheter with foraminous anchor
US5341818A (en) 1992-12-22 1994-08-30 Advanced Cardiovascular Systems, Inc. Guidewire with superelastic distal portion
US5224945A (en) * 1992-01-13 1993-07-06 Interventional Technologies, Inc. Compressible/expandable atherectomy cutter
US5792157A (en) * 1992-11-13 1998-08-11 Scimed Life Systems, Inc. Expandable intravascular occlusion material removal devices and methods of use
EP0794734B1 (en) 1993-04-29 2002-08-28 SciMed Life Systems, Inc. Expandable intravascular occlusion material removal device
US5556389A (en) 1994-03-31 1996-09-17 Liprie; Samuel F. Method and apparatus for treating stenosis or other constriction in a bodily conduit
DE69536046D1 (en) 1994-07-08 2010-04-01 Ev3 Inc System for performing an intravascular procedure
US5681347A (en) 1995-05-23 1997-10-28 Boston Scientific Corporation Vena cava filter delivery system
FR2737654B1 (en) 1995-08-10 1997-11-21 Braun Celsa Sa FILTRATION UNIT FOR THE RETENTION OF BLOOD CLOTS
US6544276B1 (en) 1996-05-20 2003-04-08 Medtronic Ave. Inc. Exchange method for emboli containment
US5972019A (en) * 1996-07-25 1999-10-26 Target Therapeutics, Inc. Mechanical clot treatment device
US5882329A (en) * 1997-02-12 1999-03-16 Prolifix Medical, Inc. Apparatus and method for removing stenotic material from stents
US6152946A (en) 1998-03-05 2000-11-28 Scimed Life Systems, Inc. Distal protection device and method
US6974469B2 (en) 1997-03-06 2005-12-13 Scimed Life Systems, Inc. Distal protection device and method
EP0934092A4 (en) 1997-03-06 2008-03-26 Boston Scient Scimed Inc Distal protection device and method
US7094249B1 (en) 1997-03-06 2006-08-22 Boston Scientific Scimed, Inc. Distal protection device and method
WO1998047447A1 (en) * 1997-04-23 1998-10-29 Dubrul William R Bifurcated stent and distal protection system
US6676682B1 (en) 1997-05-08 2004-01-13 Scimed Life Systems, Inc. Percutaneous catheter and guidewire having filter and medical device deployment capabilities
US5954745A (en) * 1997-05-16 1999-09-21 Gertler; Jonathan Catheter-filter set having a compliant seal
US6761727B1 (en) 1997-06-02 2004-07-13 Medtronic Ave, Inc. Filter assembly
US6059814A (en) * 1997-06-02 2000-05-09 Medtronic Ave., Inc. Filter for filtering fluid in a bodily passageway
DE19723700A1 (en) 1997-06-06 1998-12-10 Sherine Med Ag Device for sealing hollow vessels
AU751056B2 (en) 1998-04-02 2002-08-08 Salviac Limited Delivery catheter
US6237295B1 (en) * 1999-02-04 2001-05-29 Ballard International Distributing Flooring assembly and fastener therefor
US6537296B2 (en) 1999-04-01 2003-03-25 Scion Cardio-Vascular, Inc. Locking frame, filter and deployment system
US6277139B1 (en) 1999-04-01 2001-08-21 Scion Cardio-Vascular, Inc. Vascular protection and embolic material retriever
US6277138B1 (en) * 1999-08-17 2001-08-21 Scion Cardio-Vascular, Inc. Filter for embolic material mounted on expandable frame
AU3844799A (en) 1999-05-07 2000-11-21 Salviac Limited A filter element with retractable guidewire tip
AU3844399A (en) 1999-05-07 2000-11-21 Salviac Limited Support frame for embolic protection device
US6468291B2 (en) 1999-07-16 2002-10-22 Baff Llc Emboli filtration system having integral strut arrangement and methods of use
US6589263B1 (en) 1999-07-30 2003-07-08 Incept Llc Vascular device having one or more articulation regions and methods of use
US6346116B1 (en) 1999-08-03 2002-02-12 Medtronic Ave, Inc. Distal protection device
US6142987A (en) 1999-08-03 2000-11-07 Scimed Life Systems, Inc. Guided filter with support wire and methods of use
ATE410975T1 (en) * 1999-08-27 2008-10-15 Ev3 Inc SLIDING VASCULAR FILTER
US6540722B1 (en) 1999-12-30 2003-04-01 Advanced Cardiovascular Systems, Inc. Embolic protection devices
US6361546B1 (en) 2000-01-13 2002-03-26 Endotex Interventional Systems, Inc. Deployable recoverable vascular filter and methods for use
GB2369575A (en) 2000-04-20 2002-06-05 Salviac Ltd An embolic protection system
US6602271B2 (en) 2000-05-24 2003-08-05 Medtronic Ave, Inc. Collapsible blood filter with optimal braid geometry
US7285126B2 (en) 2000-06-29 2007-10-23 Concentric Medical, Inc. Systems, methods and devices for removing obstructions from a blood vessel
US6740061B1 (en) 2000-07-28 2004-05-25 Ev3 Inc. Distal protection device
US6616680B1 (en) 2000-11-01 2003-09-09 Joseph M. Thielen Distal protection and delivery system and method
US7169165B2 (en) 2001-01-16 2007-01-30 Boston Scientific Scimed, Inc. Rapid exchange sheath for deployment of medical devices and methods of use
US6537295B2 (en) 2001-03-06 2003-03-25 Scimed Life Systems, Inc. Wire and lock mechanism
US6890340B2 (en) 2001-11-29 2005-05-10 Medtronic Vascular, Inc. Apparatus for temporary intraluminal protection
US6773448B2 (en) 2002-03-08 2004-08-10 Ev3 Inc. Distal protection devices having controllable wire motion
US7192434B2 (en) * 2002-03-08 2007-03-20 Ev3 Inc. Vascular protection devices and methods of use
US20030176884A1 (en) 2002-03-12 2003-09-18 Marwane Berrada Everted filter device
US7166120B2 (en) 2002-07-12 2007-01-23 Ev3 Inc. Catheter with occluding cuff
US7232452B2 (en) 2002-07-12 2007-06-19 Ev3 Inc. Device to create proximal stasis
KR102177210B1 (en) 2013-08-19 2020-11-11 삼성디스플레이 주식회사 Method for testing susceptor of chemical vapor deposition apparatus and method for manufacturing organic light emitting display apparatus by using the same

Patent Citations (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4665906A (en) * 1983-10-14 1987-05-19 Raychem Corporation Medical devices incorporating sim alloy elements
US5067957A (en) * 1983-10-14 1991-11-26 Raychem Corporation Method of inserting medical devices incorporating SIM alloy elements
US5597378A (en) * 1983-10-14 1997-01-28 Raychem Corporation Medical devices incorporating SIM alloy elements
US5190546A (en) * 1983-10-14 1993-03-02 Raychem Corporation Medical devices incorporating SIM alloy elements
US4619246A (en) * 1984-05-23 1986-10-28 William Cook, Europe A/S Collapsible filter basket
US4873978A (en) * 1987-12-04 1989-10-17 Robert Ginsburg Device and method for emboli retrieval
US5496277A (en) * 1990-04-12 1996-03-05 Schneider (Usa) Inc. Radially expandable body implantable device
US5071407A (en) * 1990-04-12 1991-12-10 Schneider (U.S.A.) Inc. Radially expandable fixation member
US5171233A (en) * 1990-04-25 1992-12-15 Microvena Corporation Snare-type probe
US5108419A (en) * 1990-08-16 1992-04-28 Evi Corporation Endovascular filter and method for use thereof
US5160342A (en) * 1990-08-16 1992-11-03 Evi Corp. Endovascular filter and method for use thereof
US5192286A (en) * 1991-07-26 1993-03-09 Regents Of The University Of California Method and device for retrieving materials from body lumens
US6123715A (en) * 1994-07-08 2000-09-26 Amplatz; Curtis Method of forming medical devices; intravascular occlusion devices
US5695519A (en) * 1995-11-30 1997-12-09 American Biomed, Inc. Percutaneous filter for carotid angioplasty
US6096053A (en) * 1996-05-03 2000-08-01 Scimed Life Systems, Inc. Medical retrieval basket
US6270477B1 (en) * 1996-05-20 2001-08-07 Percusurge, Inc. Catheter for emboli containment
US6050972A (en) * 1996-05-20 2000-04-18 Percusurge, Inc. Guidewire inflation system
US5814064A (en) * 1997-03-06 1998-09-29 Scimed Life Systems, Inc. Distal protection device
US5827324A (en) * 1997-03-06 1998-10-27 Scimed Life Systems, Inc. Distal protection device
US6001118A (en) * 1997-03-06 1999-12-14 Scimed Life Systems, Inc. Distal protection device and method
US6245089B1 (en) * 1997-03-06 2001-06-12 Scimed Life Systems, Inc. Distal protection device and method
US5911734A (en) * 1997-05-08 1999-06-15 Embol-X, Inc. Percutaneous catheter and guidewire having filter and medical device deployment capabilities
US6027520A (en) * 1997-05-08 2000-02-22 Embol-X, Inc. Percutaneous catheter and guidewire having filter and medical device deployment capabilities
US5910154A (en) * 1997-05-08 1999-06-08 Embol-X, Inc. Percutaneous catheter and guidewire having filter and medical device deployment
US6336934B1 (en) * 1997-11-07 2002-01-08 Salviac Limited Embolic protection device
US6231588B1 (en) * 1998-08-04 2001-05-15 Percusurge, Inc. Low profile catheter for angioplasty and occlusion
US6287321B1 (en) * 1998-10-13 2001-09-11 Embol-X, Inc. Percutaneous filtration catheter for valve repair surgery
US6171327B1 (en) * 1999-02-24 2001-01-09 Scimed Life Systems, Inc. Intravascular filter and method
US6245012B1 (en) * 1999-03-19 2001-06-12 Nmt Medical, Inc. Free standing filter
US6179859B1 (en) * 1999-07-16 2001-01-30 Baff Llc Emboli filtration system and methods of use
US6129739A (en) * 1999-07-30 2000-10-10 Incept Llc Vascular device having one or more articulation regions and methods of use
US6214026B1 (en) * 1999-07-30 2001-04-10 Incept Llc Delivery system for a vascular device with articulation region
US6179861B1 (en) * 1999-07-30 2001-01-30 Incept Llc Vascular device having one or more articulation regions and methods of use
US6325815B1 (en) * 1999-09-21 2001-12-04 Microvena Corporation Temporary vascular filter
US6371971B1 (en) * 1999-11-15 2002-04-16 Scimed Life Systems, Inc. Guidewire filter and methods of use

Cited By (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7828816B2 (en) 1994-07-08 2010-11-09 Ev3 Inc. Method and device for filtering body fluid
US7947060B2 (en) 1994-07-08 2011-05-24 Tyco Healthcare Group Lp Method and device for filtering body fluid
US7670355B2 (en) 1994-07-08 2010-03-02 Ev3 Inc. Method and device for filtering body fluid
US7670356B2 (en) 1994-07-08 2010-03-02 Ev3 Inc. Method and device for filtering body fluid
US7678130B2 (en) 1994-07-08 2010-03-16 Ev3 Inc. Method and device for filtering body fluid
US7686815B2 (en) 1994-07-08 2010-03-30 Ev3 Inc. Method and device for filtering body fluid
US7922732B2 (en) 1994-07-08 2011-04-12 Tyco Healthcare Group Lp Method and device for filtering body fluid
US8956382B2 (en) 1999-08-27 2015-02-17 Covidien Lp Slideable vascular filter
US9649184B2 (en) 1999-08-27 2017-05-16 Covidien Lp Slidable vascular filter
US20080119889A1 (en) * 1999-08-27 2008-05-22 Ev3 Inc. Slideable vascular filter
US7942893B2 (en) * 2001-02-28 2011-05-17 Boston Scientific Scimed, Inc. Filter retrieval catheter
US8083762B2 (en) 2002-03-08 2011-12-27 Tyco Healthcare Group Lp Distal protection devices having controllable wire motion
US10555799B2 (en) 2002-03-08 2020-02-11 Covidien Lp Distal protection devices having controllable wire motion
US9775701B2 (en) 2002-03-08 2017-10-03 Covidien Lp Distal protection devices having controllable wire motion
US9468514B2 (en) 2002-03-12 2016-10-18 Covidien Lp Everted filter device
US20110130784A1 (en) * 2002-07-12 2011-06-02 Ev3 Inc. Catheter with occluding cuff
US10136906B2 (en) 2002-07-12 2018-11-27 Covidien Lp Catheter with occluding cuff
US8721674B2 (en) 2002-07-12 2014-05-13 Covidien Lp Catheter with occluding cuff
US8795315B2 (en) 2004-10-06 2014-08-05 Cook Medical Technologies Llc Emboli capturing device having a coil and method for capturing emboli
US8221446B2 (en) 2005-03-15 2012-07-17 Cook Medical Technologies Embolic protection device
US8945169B2 (en) 2005-03-15 2015-02-03 Cook Medical Technologies Llc Embolic protection device
US8845677B2 (en) 2005-06-20 2014-09-30 Cook Medical Technologies Llc Retrievable device having a reticulation portion with staggered struts
US7850708B2 (en) 2005-06-20 2010-12-14 Cook Incorporated Embolic protection device having a reticulated body with staggered struts
US8109962B2 (en) 2005-06-20 2012-02-07 Cook Medical Technologies Llc Retrievable device having a reticulation portion with staggered struts
US7766934B2 (en) 2005-07-12 2010-08-03 Cook Incorporated Embolic protection device with an integral basket and bag
US7867247B2 (en) 2005-07-12 2011-01-11 Cook Incorporated Methods for embolic protection during treatment of a stenotic lesion in a body vessel
US7771452B2 (en) 2005-07-12 2010-08-10 Cook Incorporated Embolic protection device with a filter bag that disengages from a basket
US8187298B2 (en) 2005-08-04 2012-05-29 Cook Medical Technologies Llc Embolic protection device having inflatable frame
US8377092B2 (en) 2005-09-16 2013-02-19 Cook Medical Technologies Llc Embolic protection device
US8632562B2 (en) 2005-10-03 2014-01-21 Cook Medical Technologies Llc Embolic protection device
US8182508B2 (en) 2005-10-04 2012-05-22 Cook Medical Technologies Llc Embolic protection device
US8252017B2 (en) 2005-10-18 2012-08-28 Cook Medical Technologies Llc Invertible filter for embolic protection
US8216269B2 (en) 2005-11-02 2012-07-10 Cook Medical Technologies Llc Embolic protection device having reduced profile
US8152831B2 (en) 2005-11-17 2012-04-10 Cook Medical Technologies Llc Foam embolic protection device
US8696622B2 (en) 2006-02-01 2014-04-15 DePuy Synthes Products, LLC Method and apparatus for increasing blood flow through an obstructed blood vessel
US8366663B2 (en) 2006-02-01 2013-02-05 The Cleveland Clinic Foundation Method and apparatus for increasing blood flow through an obstructed blood vessel
US8702652B2 (en) 2006-02-01 2014-04-22 DePuy Synthes Products, LLC Method and apparatus for increasing blood flow through an obstructed blood vessel
US8317748B2 (en) 2006-02-01 2012-11-27 The Cleveland Clinic Foundation Method and apparatus for increasing blood flow through an obstructed blood vessel
US8052640B2 (en) 2006-02-01 2011-11-08 The Cleveland Clinic Foundation Method and apparatus for increasing blood flow through an obstructed blood vessel
US10201359B2 (en) 2006-02-01 2019-02-12 Cleveland Clinic Foundation, The Method and apparatus for increasing blood flow through an obstructed blood vessel
US9907639B2 (en) 2006-09-19 2018-03-06 Cook Medical Technologies Llc Apparatus and methods for in situ embolic protection
US9901434B2 (en) 2007-02-27 2018-02-27 Cook Medical Technologies Llc Embolic protection device including a Z-stent waist band
US20090052804A1 (en) * 2007-08-22 2009-02-26 Prospect Technologies, Inc. Method process and apparatus for automated document scanning and management system
US9398946B2 (en) 2007-09-14 2016-07-26 Cook Medical Technologies Llc Expandable device for treatment of a stricture in a body vessel
US9138307B2 (en) 2007-09-14 2015-09-22 Cook Medical Technologies Llc Expandable device for treatment of a stricture in a body vessel
US8419748B2 (en) 2007-09-14 2013-04-16 Cook Medical Technologies Llc Helical thrombus removal device
US8252018B2 (en) 2007-09-14 2012-08-28 Cook Medical Technologies Llc Helical embolic protection device
US8657849B2 (en) 2008-12-29 2014-02-25 Cook Medical Technologies Llc Embolic protection device and method of use
US8388644B2 (en) 2008-12-29 2013-03-05 Cook Medical Technologies Llc Embolic protection device and method of use

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US20070005105A1 (en) 2007-01-04
WO2001021100A1 (en) 2001-03-29
ES2376750T3 (en) 2012-03-16
ATE365516T1 (en) 2007-07-15
US20120035649A1 (en) 2012-02-09
US20080045998A1 (en) 2008-02-21
EP1214016B1 (en) 2007-06-27
EP1214016A1 (en) 2002-06-19
EP1825833B1 (en) 2011-11-02
US20020032460A1 (en) 2002-03-14
US8562637B2 (en) 2013-10-22
US6325815B1 (en) 2001-12-04
DE60035353D1 (en) 2007-08-09
DE60035353T2 (en) 2008-03-06
EP1825833A3 (en) 2009-09-02
US20100152768A1 (en) 2010-06-17
US9039727B2 (en) 2015-05-26
JP2003509155A (en) 2003-03-11
AU7375800A (en) 2001-04-24
ES2287030T3 (en) 2007-12-16
ATE531337T1 (en) 2011-11-15
US20040102807A1 (en) 2004-05-27
EP1825833A2 (en) 2007-08-29

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