EP1631577A4 - Method and apparatus for recognizing molecular compounds - Google Patents

Method and apparatus for recognizing molecular compounds

Info

Publication number
EP1631577A4
EP1631577A4 EP03741837A EP03741837A EP1631577A4 EP 1631577 A4 EP1631577 A4 EP 1631577A4 EP 03741837 A EP03741837 A EP 03741837A EP 03741837 A EP03741837 A EP 03741837A EP 1631577 A4 EP1631577 A4 EP 1631577A4
Authority
EP
European Patent Office
Prior art keywords
molecular compounds
recognizing molecular
recognizing
compounds
molecular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03741837A
Other languages
German (de)
French (fr)
Other versions
EP1631577A1 (en
Inventor
William Rassman
David Ralin
Feimeng Zhou
Shubo Han
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Maven Technologies LLC
Original Assignee
Maven Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maven Technologies LLC filed Critical Maven Technologies LLC
Publication of EP1631577A1 publication Critical patent/EP1631577A1/en
Publication of EP1631577A4 publication Critical patent/EP1631577A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/21—Polarisation-affecting properties
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N2021/757—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated using immobilised reagents
EP03741837A 2003-05-28 2003-05-28 Method and apparatus for recognizing molecular compounds Withdrawn EP1631577A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15899503A 2003-05-28 2003-05-28
PCT/US2003/017137 WO2004106357A1 (en) 2003-05-28 2003-05-28 Method and apparatus for recognizing molecular compounds

Publications (2)

Publication Number Publication Date
EP1631577A1 EP1631577A1 (en) 2006-03-08
EP1631577A4 true EP1631577A4 (en) 2008-07-23

Family

ID=33488861

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03741837A Withdrawn EP1631577A4 (en) 2003-05-28 2003-05-28 Method and apparatus for recognizing molecular compounds

Country Status (5)

Country Link
EP (1) EP1631577A4 (en)
JP (1) JP2007528692A (en)
CN (1) CN1823085A (en)
AU (1) AU2003304150A1 (en)
WO (1) WO2004106357A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005041584B4 (en) * 2005-09-01 2007-08-16 Universität Karlsruhe (Th) Differential measurement method for determining concentration differences for supersaturation determination
US9803236B2 (en) 2010-08-06 2017-10-31 Tsinghua University Microarray-based assay integrated with particles for analyzing molecular interactions
CN103760355B (en) 2013-12-05 2015-09-16 博奥生物集团有限公司 Micro-array chip detects the particle marker method of nucleotide sequence
US10900030B2 (en) 2015-04-14 2021-01-26 Illumina, Inc. Structured substrates for improving detection of light emissions and methods relating to the same
KR101663910B1 (en) * 2015-09-01 2016-10-07 고려대학교 산학협력단 Sensor for detection of zinc oxide nanowire in water and method for detection of zinc oxide nanowire using the sensor
CN105891306B (en) * 2016-06-24 2019-04-26 北京化工大学 A kind of method of antibody modification nanosphere electrophoresis flow model ELISA
CN107101981A (en) * 2017-03-03 2017-08-29 南京农业大学 A kind of method that utilization utilizing total internal reflection fluorescence microscope detects single biological marker

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4608344A (en) * 1981-09-18 1986-08-26 Battelle Memorial Institute Method for the determination of species in solution with an optical wave-guide
WO1998009156A1 (en) * 1996-08-29 1998-03-05 Novartis Ag Optical chemical / biochemical sensor
WO1998037066A1 (en) * 1996-02-26 1998-08-27 California Institute Of Technology Improved polyamides for binding in the minor groove of double stranded dna
WO2005035790A1 (en) * 2003-09-12 2005-04-21 Maven Technologies, Llc Method and apparatus for recognizing molecular compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0067921B1 (en) * 1981-06-22 1987-11-11 Prutec Limited A method for determining bioactive substances
DK0667918T3 (en) * 1991-11-14 2000-06-05 Dgi Inc Non-radioactive hybridization assay and kit
DE19628002C1 (en) * 1996-07-11 1997-12-18 Inst Chemo Biosensorik Device and method for carrying out fluorescence immunoassays
US7023547B2 (en) * 2000-07-11 2006-04-04 Maven Technologies, Llc Apparatus including a biochip for imaging of biological samples and method
US6594011B1 (en) * 2000-07-11 2003-07-15 Maven Technologies, Llc Imaging apparatus and method
US20020093654A1 (en) * 2000-07-11 2002-07-18 Lieberman Robert A. Apparatus and method for imaging

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4608344A (en) * 1981-09-18 1986-08-26 Battelle Memorial Institute Method for the determination of species in solution with an optical wave-guide
WO1998037066A1 (en) * 1996-02-26 1998-08-27 California Institute Of Technology Improved polyamides for binding in the minor groove of double stranded dna
WO1998009156A1 (en) * 1996-08-29 1998-03-05 Novartis Ag Optical chemical / biochemical sensor
WO2005035790A1 (en) * 2003-09-12 2005-04-21 Maven Technologies, Llc Method and apparatus for recognizing molecular compounds

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
BIER F F ET AL: "Label-free observation of DNA-hybridisation and endonuclease activity on a wave guide surface using a grating coupler", BIOSENSORS & BIOELECTRONICS, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 11, no. 6-7, 1996, pages 669 - 674, XP002281013, ISSN: 0956-5663 *
BOHRMANN B ET AL: "Immunostraining of DNA in electron microscopy: an amplification and straining procedure for thin sections aa alternative to gold labeling", JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY, HISTOCHEMICAL SOCIETY, NEW YORK, NY, US, vol. 42, no. 5, 1994, pages 635 - 643, XP008030957, ISSN: 0022-1554 *
HE L ET AL: "Colloidal Au-enhanced surface plasmon resonance for ultrasensitive detection of DNA hybridization", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, vol. 122, 2000, pages 9071 - 9077, XP002206375, ISSN: 0002-7863 *
POLZIUS R ET AL: "Real-time observation of affinity reactions using grating couplers: Determination of the detection limit and calculation of kinetic rate constants", ANALYTICAL BIOCHEMISTRY, ACADEMIC PRESS, SAN DIEGO, CA, US, vol. 248, no. 2, 1997, pages 269 - 276, XP002281014, ISSN: 0003-2697 *
SCHNEIDER B H ET AL: "Hartman interferometer: Versatile integrated optic sensor for label-free, real-time quantification of nucleic acids, proteins, and pathogens", CLINICAL CHEMISTRY, AMERICAN ASSOCIATION FOR CLINICAL CHEMISTRY, WASHINGTON, DC, US, vol. 43, no. 9, 1997, pages 1757 - 1763, XP002281012, ISSN: 0009-9147 *
SCHNEIDER B H ET AL: "Optical chip immunoassay for hCG in human whole blood", BIOSENSORS & BIOELECTRONICS, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 15, no. 11-12, December 2000 (2000-12-01), pages 597 - 604, XP002281252, ISSN: 0956-5663 *
See also references of WO2004106357A1 *
WINK T ET AL: "Liposome-mediated enhancement of the sensitivity in immunoassays of proteins and peptides in surface plasmon resonance spectrometry", 1 March 1998, ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. COLUMBUS, US, PAGE(S) 827-832, ISSN: 0003-2700, XP002206192 *

Also Published As

Publication number Publication date
CN1823085A (en) 2006-08-23
WO2004106357A1 (en) 2004-12-09
JP2007528692A (en) 2007-10-18
AU2003304150A1 (en) 2005-01-21
EP1631577A1 (en) 2006-03-08

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