DE69938013D1 - Vorrichtung zur Elektroporation ohne Gewebepenetration - Google Patents
Vorrichtung zur Elektroporation ohne GewebepenetrationInfo
- Publication number
- DE69938013D1 DE69938013D1 DE69938013T DE69938013T DE69938013D1 DE 69938013 D1 DE69938013 D1 DE 69938013D1 DE 69938013 T DE69938013 T DE 69938013T DE 69938013 T DE69938013 T DE 69938013T DE 69938013 D1 DE69938013 D1 DE 69938013D1
- Authority
- DE
- Germany
- Prior art keywords
- target tissue
- electrodes
- establish
- electromagnetic field
- support
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
- A61N1/0416—Anode and cathode
- A61N1/0424—Shape of the electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/0476—Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/213,218 US6314316B1 (en) | 1998-12-17 | 1998-12-17 | Nonpenetrating electroporation device and method |
US213218 | 1998-12-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69938013D1 true DE69938013D1 (de) | 2008-03-06 |
DE69938013T2 DE69938013T2 (de) | 2009-01-15 |
Family
ID=22794209
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69923787T Expired - Lifetime DE69923787T2 (de) | 1998-12-17 | 1999-12-15 | Vorrichtung zur elektroporation ohne gewebepenetration |
DE69938013T Expired - Lifetime DE69938013T2 (de) | 1998-12-17 | 1999-12-15 | Vorrichtung zur Elektroporation ohne Gewebepenetration |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69923787T Expired - Lifetime DE69923787T2 (de) | 1998-12-17 | 1999-12-15 | Vorrichtung zur elektroporation ohne gewebepenetration |
Country Status (8)
Country | Link |
---|---|
US (1) | US6314316B1 (de) |
EP (2) | EP1140282B1 (de) |
JP (1) | JP2002532166A (de) |
AT (1) | ATE289215T1 (de) |
AU (1) | AU768451B2 (de) |
CA (1) | CA2355051C (de) |
DE (2) | DE69923787T2 (de) |
WO (1) | WO2000035532A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6714816B1 (en) * | 2000-02-22 | 2004-03-30 | University Of South Florida | Electroporation and electrophoresis system and method for achieving molecular penetration into cells in vivo |
AU2002245675A1 (en) * | 2001-03-13 | 2002-09-24 | University Of South Florida | Electromanipulation device and method |
US8209006B2 (en) * | 2002-03-07 | 2012-06-26 | Vgx Pharmaceuticals, Inc. | Constant current electroporation device and methods of use |
US7245963B2 (en) * | 2002-03-07 | 2007-07-17 | Advisys, Inc. | Electrode assembly for constant-current electroporation and use |
WO2006080934A2 (en) * | 2004-04-19 | 2006-08-03 | Invitrogen Corporation | Electroporation apparatus and methods |
ES2367921T3 (es) * | 2005-04-18 | 2011-11-10 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Procedimiento y dispositivos para el suministro de un producto terapéutico a la esfera ocular de un paciente. |
WO2007117651A2 (en) | 2006-04-07 | 2007-10-18 | University Of South Florida | Passive electric field focus system for in vivo and in vitro applications |
DE102006022554B4 (de) * | 2006-05-15 | 2014-12-04 | Roche Diagnostics Gmbh | Verfahren und Vorrichtung zum Stimulieren eines Gewebes für die subkutane Verabreichung von Wirkstoffen |
EP4328297A2 (de) * | 2008-01-17 | 2024-02-28 | Inovio Pharmaceuticals, Inc. | Einzelnadelelektroporationssystem und -verfahren mit variabler stromdichte |
WO2010106544A1 (en) * | 2009-03-16 | 2010-09-23 | Rajah Vijay Kumar | A method and apparatus for - focused resonance nanopermeabilization (forn) |
WO2016017045A1 (ja) * | 2014-07-28 | 2016-02-04 | ネッパジーン株式会社 | エレクトロポレーター用電気パルス発生器及び前記電気パルス発生器を備えたエレクトロポレーター装置 |
JP5822247B1 (ja) * | 2014-07-28 | 2015-11-24 | ネッパジーン株式会社 | エレクトロポレーター用電気パルス発生器及び前記電気パルス発生器を備えたエレクトロポレーター装置 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1099062A (en) * | 1913-12-10 | 1914-06-02 | Peter P Laposkey | Electric scalp appliance. |
US4970154A (en) * | 1987-10-09 | 1990-11-13 | Baylor College Of Medicine | Method for inserting foreign genes into cells using pulsed radiofrequency |
US5318514A (en) | 1992-08-17 | 1994-06-07 | Btx, Inc. | Applicator for the electroporation of drugs and genes into surface cells |
US6009345A (en) * | 1992-08-17 | 1999-12-28 | Genetronics, Inc. | Method and apparatus for a combination of electroporation and iontophoresis for the delivery of drugs and genes |
FR2703253B1 (fr) | 1993-03-30 | 1995-06-23 | Centre Nat Rech Scient | Applicateur d'impulsions electriques pour traitement de tissus biologiques. |
US5993434A (en) | 1993-04-01 | 1999-11-30 | Genetronics, Inc. | Method of treatment using electroporation mediated delivery of drugs and genes |
US5439440A (en) | 1993-04-01 | 1995-08-08 | Genetronics, Inc. | Electroporation system with voltage control feedback for clinical applications |
US5707349A (en) * | 1994-05-09 | 1998-01-13 | Somnus Medical Technologies, Inc. | Method for treatment of air way obstructions |
US5983130A (en) * | 1995-06-07 | 1999-11-09 | Alza Corporation | Electrotransport agent delivery method and apparatus |
JPH09266954A (ja) * | 1996-04-03 | 1997-10-14 | Meiwa Shoji Kk | 電極付治療器具 |
US5869326A (en) * | 1996-09-09 | 1999-02-09 | Genetronics, Inc. | Electroporation employing user-configured pulsing scheme |
US5873849A (en) * | 1997-04-24 | 1999-02-23 | Ichor Medical Systems, Inc. | Electrodes and electrode arrays for generating electroporation inducing electrical fields |
-
1998
- 1998-12-17 US US09/213,218 patent/US6314316B1/en not_active Expired - Lifetime
-
1999
- 1999-12-15 DE DE69923787T patent/DE69923787T2/de not_active Expired - Lifetime
- 1999-12-15 JP JP2000587848A patent/JP2002532166A/ja active Pending
- 1999-12-15 EP EP99964257A patent/EP1140282B1/de not_active Expired - Lifetime
- 1999-12-15 CA CA002355051A patent/CA2355051C/en not_active Expired - Fee Related
- 1999-12-15 EP EP04078056A patent/EP1504787B1/de not_active Expired - Lifetime
- 1999-12-15 DE DE69938013T patent/DE69938013T2/de not_active Expired - Lifetime
- 1999-12-15 WO PCT/US1999/029722 patent/WO2000035532A1/en active IP Right Grant
- 1999-12-15 AT AT99964257T patent/ATE289215T1/de not_active IP Right Cessation
- 1999-12-15 AU AU20536/00A patent/AU768451B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
JP2002532166A (ja) | 2002-10-02 |
AU768451B2 (en) | 2003-12-11 |
EP1504787A1 (de) | 2005-02-09 |
EP1140282A1 (de) | 2001-10-10 |
WO2000035532A1 (en) | 2000-06-22 |
EP1140282B1 (de) | 2005-02-16 |
CA2355051C (en) | 2003-12-09 |
DE69923787D1 (de) | 2005-03-24 |
AU2053600A (en) | 2000-07-03 |
DE69938013T2 (de) | 2009-01-15 |
DE69923787T2 (de) | 2006-01-05 |
US6314316B1 (en) | 2001-11-06 |
CA2355051A1 (en) | 2000-06-22 |
ATE289215T1 (de) | 2005-03-15 |
EP1504787B1 (de) | 2008-01-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |