DE69828793D1 - Fluoreszierender polymer-sensor zur erfassung von harnstoff - Google Patents

Fluoreszierender polymer-sensor zur erfassung von harnstoff

Info

Publication number
DE69828793D1
DE69828793D1 DE69828793T DE69828793T DE69828793D1 DE 69828793 D1 DE69828793 D1 DE 69828793D1 DE 69828793 T DE69828793 T DE 69828793T DE 69828793 T DE69828793 T DE 69828793T DE 69828793 D1 DE69828793 D1 DE 69828793D1
Authority
DE
Germany
Prior art keywords
urea
detection
layer
fluorophore
sensor material
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69828793T
Other languages
English (en)
Other versions
DE69828793T2 (de
Inventor
Christiane Munkholm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Application granted granted Critical
Publication of DE69828793D1 publication Critical patent/DE69828793D1/de
Publication of DE69828793T2 publication Critical patent/DE69828793T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/58—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving urea or urease
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/17—Nitrogen containing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/17—Nitrogen containing
    • Y10T436/171538—Urea or blood urea nitrogen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/17—Nitrogen containing
    • Y10T436/173845—Amine and quaternary ammonium
    • Y10T436/175383—Ammonia
DE69828793T 1997-08-05 1998-08-03 Fluoreszierender polymer-sensor zur erfassung von harnstoff Expired - Fee Related DE69828793T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/906,518 US5945343A (en) 1997-08-05 1997-08-05 Fluorescent polymeric sensor for the detection of urea
US906518 1997-08-05
PCT/IB1998/001183 WO1999007882A1 (en) 1997-08-05 1998-08-03 Fluorescent polymeric sensor for the detection of urea

Publications (2)

Publication Number Publication Date
DE69828793D1 true DE69828793D1 (de) 2005-03-03
DE69828793T2 DE69828793T2 (de) 2006-01-05

Family

ID=25422583

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69828793T Expired - Fee Related DE69828793T2 (de) 1997-08-05 1998-08-03 Fluoreszierender polymer-sensor zur erfassung von harnstoff

Country Status (9)

Country Link
US (1) US5945343A (de)
EP (1) EP1000171B1 (de)
JP (1) JP2001512693A (de)
AT (1) ATE287967T1 (de)
AU (1) AU8354198A (de)
DE (1) DE69828793T2 (de)
DK (1) DK1000171T3 (de)
ES (1) ES2236917T3 (de)
WO (1) WO1999007882A1 (de)

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US6254830B1 (en) * 1999-11-05 2001-07-03 The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations Magnetic focusing immunosensor for the detection of pathogens
US6291200B1 (en) 1999-11-17 2001-09-18 Agentase, Llc Enzyme-containing polymeric sensors
US6750033B2 (en) 2001-05-07 2004-06-15 Agentase, Llc Positive response biosensors and other sensors
DE10143517A1 (de) * 2001-09-05 2003-03-27 Hte Ag The High Throughput Exp Verfahren und Vorrichtung zur Analyse eines fluiden Mediums
CA2582504A1 (en) 2004-10-06 2006-04-20 Agentase, Llc Enzyme-based device for environmental monitoring
US7422892B2 (en) 2004-10-06 2008-09-09 Agentase, Llc Enzyme-based device for environmental monitoring
US20060134716A1 (en) * 2004-12-16 2006-06-22 Pelagia-Irene Gouma Electrospun enzyme-nanocomposite biosensing material
US8617366B2 (en) * 2005-12-12 2013-12-31 Nova Biomedical Corporation Disposable urea sensor and system for determining creatinine and urea nitrogen-to-creatinine ratio in a single device
US8409864B2 (en) * 2006-01-06 2013-04-02 Renal Solutions, Inc. Ammonia sensor and system for use
US7449579B1 (en) 2006-05-02 2008-11-11 Sandia Corporation Detection of electrophilic and nucleophilic chemical agents
US8105487B2 (en) 2007-09-25 2012-01-31 Fresenius Medical Care Holdings, Inc. Manifolds for use in conducting dialysis
US9199022B2 (en) 2008-09-12 2015-12-01 Fresenius Medical Care Holdings, Inc. Modular reservoir assembly for a hemodialysis and hemofiltration system
US8240636B2 (en) 2009-01-12 2012-08-14 Fresenius Medical Care Holdings, Inc. Valve system
US8040493B2 (en) 2007-10-11 2011-10-18 Fresenius Medical Care Holdings, Inc. Thermal flow meter
US8597505B2 (en) 2007-09-13 2013-12-03 Fresenius Medical Care Holdings, Inc. Portable dialysis machine
US9308307B2 (en) 2007-09-13 2016-04-12 Fresenius Medical Care Holdings, Inc. Manifold diaphragms
US8535522B2 (en) 2009-02-12 2013-09-17 Fresenius Medical Care Holdings, Inc. System and method for detection of disconnection in an extracorporeal blood circuit
US9358331B2 (en) 2007-09-13 2016-06-07 Fresenius Medical Care Holdings, Inc. Portable dialysis machine with improved reservoir heating system
CA3057807C (en) 2007-11-29 2021-04-20 Thomas P. Robinson System and method for conducting hemodialysis and hemofiltration
US20100084558A1 (en) * 2008-10-02 2010-04-08 Wang Su-Chee S Systems and methods for determining a concentration of urea in an aqueous solution
CN105148344B (zh) 2008-10-07 2019-06-11 弗雷塞尼斯医疗保健控股公司 用于透析系统的充灌系统和方法
WO2010062698A2 (en) 2008-10-30 2010-06-03 Xcorporeal, Inc. Modular, portable dialysis system
GB0915775D0 (en) 2009-09-09 2009-10-07 Univ Gent Implantable sensor
US10105081B2 (en) 2009-09-09 2018-10-23 Indigo Diabetes Nv Implantable sensor
DE102012021933B4 (de) * 2012-11-09 2015-12-31 Airbus Defence and Space GmbH Optischer pH-Wert-Sensor
US9201036B2 (en) 2012-12-21 2015-12-01 Fresenius Medical Care Holdings, Inc. Method and system of monitoring electrolyte levels and composition using capacitance or induction
US9157786B2 (en) 2012-12-24 2015-10-13 Fresenius Medical Care Holdings, Inc. Load suspension and weighing system for a dialysis machine reservoir
US9354640B2 (en) 2013-11-11 2016-05-31 Fresenius Medical Care Holdings, Inc. Smart actuator for valve

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DE2821469A1 (de) * 1978-05-17 1979-11-22 Boehringer Mannheim Gmbh Diagnostisches mittel zur bestimmung von harnstoff
JPS5877661A (ja) * 1981-11-02 1983-05-11 Fuji Photo Film Co Ltd アンモニアまたはアンモニア生成基質分析用一体型多層分析材料および検出法
US5198335A (en) * 1985-06-04 1993-03-30 Fuji Photo Film Co., Ltd. Integral multilayer analytical element for analysis of ammonia-forming substrate
JPH0664056B2 (ja) * 1987-04-16 1994-08-22 富士写真フイルム株式会社 アンモニア生成物質定量用一体型多層分析要素
US5005572A (en) * 1988-02-26 1991-04-09 Brigham & Women's Hospital CO2 indicator and the use thereof to evaluate placement of tracheal tubes
US5173434A (en) * 1990-11-05 1992-12-22 Baxter Diagnostics Inc. Measurement of color reactions by monitoring a change of fluorescence
US5372784A (en) * 1988-08-31 1994-12-13 Baxter Diagnostics Inc. Measurement of bacterial CO2 production in an isolated fluorophore by monitoring an absorbance regulated change of fluorescence
JP2552199B2 (ja) * 1990-10-19 1996-11-06 富士写真フイルム株式会社 アンモニア又はアンモニア生成物質定量用一体型多層分析要素
US5176980A (en) * 1991-08-08 1993-01-05 Eastman Kodak Company Electrographic liquid developer and method of making same
AT399229B (de) * 1992-04-23 1995-04-25 Avl Verbrennungskraft Messtech Sensoranordnung zur direkten oder indirekten optischen bestimmung physikalischer oder chemischer parameter
US5387525A (en) * 1993-09-03 1995-02-07 Ciba Corning Diagnostics Corp. Method for activation of polyanionic fluorescent dyes in low dielectric media with quaternary onium compounds
JP3406089B2 (ja) * 1994-10-19 2003-05-12 富士写真フイルム株式会社 両性電解質を含む乾式分析素子
US5577137A (en) * 1995-02-22 1996-11-19 American Research Corporation Of Virginia Optical chemical sensor and method using same employing a multiplicity of fluorophores contained in the free volume of a polymeric optical waveguide or in pores of a ceramic waveguide

Also Published As

Publication number Publication date
JP2001512693A (ja) 2001-08-28
EP1000171A1 (de) 2000-05-17
DE69828793T2 (de) 2006-01-05
DK1000171T3 (da) 2005-05-23
WO1999007882A1 (en) 1999-02-18
ATE287967T1 (de) 2005-02-15
ES2236917T3 (es) 2005-07-16
US5945343A (en) 1999-08-31
EP1000171B1 (de) 2005-01-26
AU8354198A (en) 1999-03-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee