CN1679768A - Ginger extract preparation and use for preventing cholelithiasis - Google Patents
Ginger extract preparation and use for preventing cholelithiasis Download PDFInfo
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- CN1679768A CN1679768A CN 200510023861 CN200510023861A CN1679768A CN 1679768 A CN1679768 A CN 1679768A CN 200510023861 CN200510023861 CN 200510023861 CN 200510023861 A CN200510023861 A CN 200510023861A CN 1679768 A CN1679768 A CN 1679768A
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- rhizoma zingiberis
- zingiberis recens
- preparation
- extract
- cholelithiasis
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Abstract
A Chinese medicine for preventing and treating cholelithiasis is prepared from the ginger extract or fresh or dried ginger and medicinal additive.
Description
Technical field:
The present invention relates to a kind of application of Rhizoma Zingiberis Recens extract.Be specifically related to a kind of ginger extract preparation and the application in the control cholelithiasis.
Background technology:
Rhizoma Zingiberis Recens is commonly called as HUANGJIANG, belong to the Zingiberaceae herbaceos perennial, originate in China and torrid areas, Southeast Asia, Rhizoma Zingiberis Recens contains fragrance strong volatile oil and gingerol, has unique peppery local flavor, be the important flavoring agent that people like, can be processed into numerous food such as Jiang Gan, Rhizoma Zingiberis powder, Sucus Zingberis, sugared ginger slices, ginger slice, oil of ginger, sugaring and saucing, the factory of domestic special exploitation ginger products still belongs to blank at present.
Rhizoma Zingiberis Recens has physiological action very widely: it can prevent carsickness, and it can treat the serious symptom vomiting, gastric and duodenal ulcers, and seborrheic dermatitis, acute inflammation, vitiligo, toothache and extreme misery are burnt or the like.Kind energy of Rhizoma Zingiberis Recens and middle preventing or arresting vomitting, the treatment cancer of the esophagus can be used as the preventing or arresting vomiting anti-emetic; Rhizoma Zingiberis Recens again can cold expelling, and dehumidifying is reduced phlegm, and invigorates blood circulation, and therefore multiple efficacies such as detoxifcation can make the medicine or the cold expelling medicine for the treatment of rheumatism; Rhizoma Zingiberis Recens is found the Rhizoma Zingiberis Recens juice growth of anticancer to a certain extent aspect the treatment tumor.According to the Japan Patent introduction, in some antitumor drug, add Rhizoma Zingiberis Recens extract, energy ameliorate tumor side effects of pharmaceutical drugs; This shows that Rhizoma Zingiberis Recens seemingly has certain " detoxifcation " effect for the poison of carcinoma.Scientists points out, " edible oil of ginger " both can analgesic wind dispelling cold expelling, and preventing or arresting vomiting is controlled headache, and preventing cold can also have stimulation to gastrointestinal mucosa, and secretion of digestive juice in the time of urging makes the appetite enhancing.Specifically, following effect is arranged usually:
(1) to the effect of digestive system: Rhizoma Zingiberis Recens has anti-hydrochloric acid-ethanol ulcer, and it can act on sympathetic nervous system, and the effect that suppresses stomach function effect and direct excited smooth muscle is arranged; (2) protect the liver the effect of function of gallbladder promoting: the gingerol of Rhizoma Zingiberis Recens all has inhibitory action to four carbonoxides and the made hepatic injury of cattle colostrums osamine, and the extracting solution of Rhizoma Zingiberis Recens has very strong choleretic effect to rat; (3) effect is told in the town: Rhizoma Zingiberis Recens has the tip town to tell effect; (4) antiinflammatory action: rat is drawn in green grass or young crops property to the fresh ginger injection and the formaldehyde swelling of the feet has tangible antiinflammatory action; (5) many central nervous system's effect: Rhizoma Zingiberis Recens has inhibitory action to the central nervous system; (6) influence of many blood circulation and respiratory system effect: the shogaol extract has excitation to pure cat vasomotor center of fiber crops and respiratory center, and heart and gallbladder is also had direct excitation; (7) antipathogen effect: to staphylococcus aureus, Staphylococcus albus, Bacillus typhi, Zhu You Shi dysentery bacterium, bacillus pyocyaneus all has obvious inhibitory action; (8) other effects: shogaol and piperic piquancy component can impel some active substance of teleneuron to discharge.
Be rich in gingerol in the Rhizoma Zingiberis Recens extract, the application of gingerol on flavoring agent is relatively more extensive, but the relevant as yet report that is used to prevent and treat cholelithiasis.
Yet when people increased fatty foodstuff day by day, the dietary habit that some are bad and other unhealthy reason caused the sickness rate of cholelithiasis to rise year by year.At present, adopt operation to solve for the treatment of cholelithiasis more, but operation often brings bigger misery to the patient, and with certain risk, the patient who has also should not undergo surgery, and when Drug therapy, act on not too obvious, the side effect that has is bigger, and new purposes is developed in the hepatic cholagogic effect how inventor's consideration uses Rhizoma Zingiberis Recens extract.
Summary of the invention:
Technical problem to be solved by this invention is the effect of postgraduate's Rhizoma Zingiberis Recens extract, is designed for the ginger extract preparation of control cholelithiasis.
The invention provides a kind of ginger extract preparation that is used to prevent and treat cholelithiasis.
Ginger extract preparation of the present invention comprises following component, in weight %:
Rhizoma Zingiberis Recens extract 0.01%-100%
Rhizoma Zingiberis Recens 0%-97%
Rhizoma Zingiberis 0%-96%
Pharmaceutic adjuvant is added into 100%
Prepare according to 22 editions disclosed methods of American Pharmacopeia at the Rhizoma Zingiberis Recens extract described in the ginger extract preparation of the present invention:
Rhizoma Zingiberis Recens, Rhizoma Zingiberis → chopping → extraction → precipitation → drying → extract
The content of gingerol is 0.7-3.0% in the preparation of the present invention, and relevant gingerol content assaying method is measured with reference to 22 editions disclosed assay methods of American Pharmacopeia.
Pharmaceutic adjuvant described in the preparation of the present invention is the required conventional adjuvant of this area pharmaceutical preparation.
Ginger extract preparation of the present invention comprises oral formulations such as capsule (smart special capsule), electuary, tablet, medicinal tea etc.
Another object of the present invention has provided the application of above-mentioned ginger extract preparation in the preparation of preparation control cholelithiasis.
Ginger extract preparation of the present invention through Shanghai * * 30 routine patient's application tests of hospital, wherein 27 examples are effectively.Following several routine patient is to show explanation:
Huang, the male suffered from cholelithiasis 5 years, took to contain gingerol capsule 9 months, and cholelithiasis narrows down to 6-9mm from 15mm, and cholelithiasis pain disappears during taking.
Xu certain, the women suffered from cholelithiasis 10 years, took to contain gingerol capsule two weeks, the cholelithiasis pain disappears.
Turn round and look at certain, the male suffered from cholelithiasis 10 years, took gingerol capsule two weeks, and the cholelithiasis pain disappears.
Ginger extract preparation of the present invention is a kind of composite preparation of plant extract, aspect the control cholelithiasis purposes is preferably being arranged, and having no side effect, the preparation method of preparation is simple and easy to do, be suitable for extensive workerization production, good using value and economic benefit are arranged.
The specific embodiment:
Embodiment 1, tablet
Rhizoma Zingiberis Recens extract 0.5g Rhizoma Zingiberis Recens 32g Rhizoma Zingiberis 57.5g cyclodextrin 9g microcrystalline Cellulose 5g polyvinylpyrrolidone 2g magnesium stearate 1g
Preparation method: 100 orders, mix homogeneously were pulverized in former dressing.Add 50% alcoholic solution that includes 5% polyvinylpyrrolidone in blended material, Bian Jialian stirs, and makes soft material, and 16 mesh sieve granulate are crossed in dry back, add the magnesium stearate mixing, regulates the heavy and pressure of sheet and carries out tabletting.Gingerol content 18mg/ sheet.
Embodiment 2, capsule
Rhizoma Zingiberis Recens 50g Rhizoma Zingiberis 40g Rhizoma Zingiberis Recens extract 0.1g magnesium stearate 1g
Fully mixed encapsulated gingerol content 12mg/ grain
Embodiment 3, capsule
Rhizoma Zingiberis Recens 97g Rhizoma Zingiberis Recens extract 0.5g magnesium stearate 2.5g
Fully mixed encapsulated gingerol content 18mg/ grain
Embodiment 4, capsule
Rhizoma Zingiberis Recens 96g Rhizoma Zingiberis Recens extract 1g cyclodextrin 2.9g magnesium stearate 1g
Fully mixed encapsulated gingerol content 13mg/ grain
Embodiment 5, electuary
Rhizoma Zingiberis Recens extract 1g cyclodextrin 20g
Fully mixed dress paper bag gingerol content 10mg/ bag
Embodiment 6, medicinal tea
Rhizoma Zingiberis Recens extract 100g directly pack makes tea
Claims (4)
1, a kind of ginger extract preparation is characterized in that said preparation comprises following component, in weight %:
Rhizoma Zingiberis Recens extract 0.01%-100%
Rhizoma Zingiberis Recens 0%-97%
Rhizoma Zingiberis 0%-96%
Pharmaceutic adjuvant is added into 100%.
2, a kind of ginger extract preparation according to claim 1 is characterized in that the gingerol content in the said preparation is 1.0-3.5%.
3, place's ginger extract preparation according to claim 1 is characterized in that comprising in the said preparation Rhizoma Zingiberis Recens and Rhizoma Zingiberis or chooses any one kind of them and Rhizoma Zingiberis Recens extract is formed active ingredient.
4, the application of the described Rhizoma Zingiberis Recens extract of a kind of claim 1 in the preparation of preparation control cholelithiasis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510023861 CN1679768A (en) | 2005-02-05 | 2005-02-05 | Ginger extract preparation and use for preventing cholelithiasis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510023861 CN1679768A (en) | 2005-02-05 | 2005-02-05 | Ginger extract preparation and use for preventing cholelithiasis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1679768A true CN1679768A (en) | 2005-10-12 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200510023861 Pending CN1679768A (en) | 2005-02-05 | 2005-02-05 | Ginger extract preparation and use for preventing cholelithiasis |
Country Status (1)
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| CN (1) | CN1679768A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9722158B2 (en) | 2009-01-14 | 2017-08-01 | Cree Huizhou Solid State Lighting Company Limited | Aligned multiple emitter package |
-
2005
- 2005-02-05 CN CN 200510023861 patent/CN1679768A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9722158B2 (en) | 2009-01-14 | 2017-08-01 | Cree Huizhou Solid State Lighting Company Limited | Aligned multiple emitter package |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |