CN102695463A - 具有提高的材料捕获效率的材料去除装置及使用方法 - Google Patents
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- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
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- A—HUMAN NECESSITIES
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- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
- A61B17/320783—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions through side-hole, e.g. sliding or rotating cutter inside catheter
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- A—HUMAN NECESSITIES
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- A61B17/32002—Endoscopic cutting instruments, e.g. arthroscopes, resectoscopes with continuously rotating, oscillating or reciprocating cutting instruments
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B2017/320064—Surgical cutting instruments with tissue or sample retaining means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
- A61B17/320783—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions through side-hole, e.g. sliding or rotating cutter inside catheter
- A61B2017/320791—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions through side-hole, e.g. sliding or rotating cutter inside catheter with cutter extending outside the cutting window
Abstract
本发明提供一种改进的粥样硬化斑块切除导管,其具有用于将由切割元件产生的颗粒导向到组织收集室中的装置。还提供了将切割的材料从血管管腔导向到组织收集室的方法。
Description
交叉引用
本申请要求2009年12月11日提交的名称为“Material RemovalDevice Having Improved Material Capture Efficiency and Methods ofUse”的美国临时专利申请No.61/285,768的权益,其内容在此以引用的方式并入本文中。
技术领域
本发明涉及用于从身体管腔中某个位置去除材料的导管。更具体地,本发明涉及能够捕获从所述位置去除的材料的导管。
背景技术
粥样硬化是血管系统的进行性疾病,其中,粥样斑块沉积在血管内壁上。随时间推移,粥样硬化沉积物可能变得足够大,以致于减小或堵塞通过血管的血流,导致低血流量症状,例如腿痛(走路时或静止时)、皮肤溃疡、心绞痛(静止时或劳力型)和其它症状。为了治疗该疾病,并且改善或消除这些症状,期望恢复或改善通过血管的血流。
多种装置用于恢复或改善通过粥样硬化血管的血流。粥样斑块沉积物可通过充气球囊、膨胀支架和其它方法将血管径向扩张来移走。但是,这些方法不合期望地撕裂和拉伸血管,在很大比例的患者中造成瘢痕形成。这种瘢痕组织(再狭窄材料)一旦形成,就会阻挡血管中的血流并且常常需要去除。该沉积物可使用激光或其它方法粉碎。但是仅仅粉碎粥样硬化材料会使微栓流动到下游,并且积聚在远端血管床中,进一步危及受疾病影响的组织的血流。粥样硬化斑块切除导管可用于从血管去除粥样硬化沉积物,并且当捕获从血管去除的粥样硬化碎片以及将其从身体去除时,可提供理想的解决方法。
当将材料从血管去除时出现的一个问题是,材料碎片可能由去除装置在一些情况下由切割器产生,并且这样的碎片可能留在体内,这样的碎片可能在体内栓塞并且造成问题。期望在材料从血管壁去除时,从身体去除形成的所有材料碎片。一些导管设计用于通过将材料颗粒导向到收集室而从身体去除材料,但是这些收集工作不总是100%有效。需要改进的颗粒收集装置。
发明内容
本发明提供一种粥样硬化斑块切除导管,包括:主体,其具有开口;可旋转轴,其联接到所述主体;组织收集室,其联接到所述主体,并且设置在切割元件的远侧;切割元件,其联接到所述可旋转轴,所述切割元件具有切割边缘;和管腔,其构造用于将流体导向到所述组织收集室中。
本发明提供一种粥样硬化斑块切除导管,包括:主体,其具有开口;可旋转轴,其联接到所述主体;组织收集室,其联接到所述主体,并且设置在切割元件远侧;切割元件,其联接到所述可旋转轴,所述切割元件具有切割边缘;和用于在所述组织收集室中向远侧推进流体的部件,所述部件选自包括以下部件的组:(i)驱动轴,其具有近端和远侧部分,所述近端附接到所述切割元件,推进器附接到所述远侧部分;和(ii)桨叶,其附接到所述切割元件。
本发明提供一种在粥样硬化斑块切除导管中再循环流体的方法,包括:提供一种粥样硬化斑块切除导管,所述粥样硬化斑块切除导管包括:主体,其具有开口;可旋转轴,其联接到所述主体;组织收集室,其联接到所述主体,并且设置在切割元件的远侧,所述组织收集室具有排放孔;切割元件,其联接到所述可旋转轴,所述切割元件具有切割边缘;和使流体通过所述排放孔移出组织收集室,以在组织收集室内部形成负压,并且该负压使流体通过所述导管的主体的开口进入所述组织收集室中。
本发明提供一种从身体管腔去除材料的方法,所述方法包括:提供一种粥样硬化斑块切除导管,所述粥样硬化斑块切除导管包括:主体,其具有开口;可旋转轴,其联接到所述主体;组织收集室,其联接到所述主体,并且设置在切割元件远侧;切割元件,其联接到所述可旋转轴,所述切割元件具有切割边缘;和管腔,其构造用于将流体导向到所述组织收集室;将所述导管放置在所述身体管腔中;和在所述身体管腔中移动所述导管,以将所述切割元件与所述身体管腔中的材料接触。
本发明提供一种从身体管腔去除材料的方法,所述方法包括:提供一种粥样硬化斑块切除导管,所述粥样硬化斑块切除导管包括:主体,其具有开口;可旋转轴,其联接到所述主体;组织收集室,其联接到所述主体,并且设置在切割元件远侧;切割元件,其联接到所述可旋转轴,所述切割元件具有切割边缘;和用于在所述组织收集室中向远侧推进流体的部件,所述部件选自包括以下部件的组:(i)驱动轴,其具有近端和远侧部分,所述近端附接到所述切割元件,推进器附接到所述远侧部分;和(ii)桨叶,其附接到所述切割元件;将所述导管放置到所述身体管腔中;和将所述导管在所述身体管腔中移动,以使所述切割元件与所述身体管腔中的材料接触。
从下面对优选实施例的描述、附图和权利要求,本发明的这些和其它方面将变得显而易见。本发明的一个或多个实施例的详细内容将在下面的附图和描述中说明。本发明的其它特征、目的和优点将通过所述描述和附图,并且通过所述权利要求变得显而易见。
附图说明
图1示出粥样硬化斑块切除导管的局部等距视图。
图2示出图1中所示的粥样硬化斑块切除导管在切割元件处于存储位置中的情况下的一部分的等距剖视图。
图3示出图1中所示的粥样硬化斑块切除导管在切割元件处于工作位置中的情况下的一部分的等距剖视图。
图4示出切割元件的一个实施例的等距视图。
图5,6和7示出具有改进的材料收集的导管的实施例的远侧部分的局部剖视图。
图7A示出图7中所示的导管的一部分的局部剖视侧视图。
图8示出切割元件的另一个实施例的等距视图。
图8A示出图8中所示的切割元件的剖视图。
图9示出具有改进的材料收集的导管的一个实施例的远侧部分的局部剖视图。
图9A,9B和9C示出用于图9中所示的导管的替代部件的局部剖视侧视图。
图10A和10B示出在血管中使用的图9中所示的导管。
具体实施方式
本发明提供一种粥样硬化斑块切除导管,包括主体,其具有开口;可旋转轴,其联接到所述主体;组织收集室,其联接到所述主体,并且设置在切割元件远侧;切割元件,其联接到所述可旋转轴,所述切割元件具有切割边缘;和管腔,其构造用于将流体导向到所述组织收集室中。在一个实施例中,所述管腔沿向远侧方向将流体导向到组织收集室中。在一个实施例中,切割元件具有杯状表面,所述杯状表面构造用于在所述杯状表面沿向远侧方向移动时,沿向远侧方向重新导向由所述切割边缘切割的组织。在一个实施例中,所述管腔在所述切割元件的杯状表面上具有远侧开口。在一个实施例中,所述管腔包括位于所述切割元件中的第一管腔部分,和位于所述可旋转轴中的第二管腔部分。在一个实施例中,所述远侧开口设置在所述切割元件的纵轴线处。在一个实施例中,所述管腔具有远侧开口,并且所述远侧开口不设置在所述切割元件的杯状表面上。在一个实施例中,所述远侧开口与所述切割元件的杯状表面相邻设置。
在一个实施例中,向管腔提供流体的流体源附接到导管的近侧部分。在一个实施例中,由流体源供给的流体为食盐水。在一个实施例中,由流体源供给的流体包含不透射线物质。
在一个实施例中,管腔的近侧开口设置在导管的远侧部分处,但是在切割元件的杯状表面近侧。在一个实施例中,所述近侧开口设置在可旋转轴上。在一个实施例中,可旋转轴包括管腔的两个或更多个近侧开口。在一个实施例中,可旋转轴包括在所述近侧开口近侧的推进器,所述推进器在可旋转轴旋转时,将流体推入近侧开口中。在一个实施例中,推进器具有1到10个螺旋圈。在一个实施例中,管腔在切割元件的杯状表面上具有远侧开口。在一个实施例中,远侧开口设置在所述切割元件的纵轴线处。
在一个实施例中,管腔的近侧开口设置在切割元件上。在一个实施例中,近侧开口设置在切割元件的外边缘处。在一个实施例中,切割元件具有杯状表面,所述杯状表面构造用于在杯状表面沿向远侧方向移动时,沿向远侧方向重新导向由所述切割边缘切割的组织,并且管腔在所述切割元件的杯状表面上具有远侧开口。在一个实施例中,远侧开口设置在切割元件的纵轴线处。
在一个实施例中,组织收集室包括排放孔。在一个实施例中,组织收集室包括10到200个排放孔。在一个实施例中,排放孔具有从25微米到100微米的直径。在一个实施例中,切割元件可相对于所述开口在存储位置和切割位置之间移动。
本发明提供一种粥样硬化斑块切除导管,包括:主体,其具有开口;可旋转轴,其联接到所述主体;组织收集室,其联接到所述主体,并且设置在切割元件远侧;切割元件,其联接到所述可旋转轴,所述切割元件具有切割边缘;和用于在组织收集室中向远侧推进流体的部件,所述部件选自包括以下部件的组:(i)驱动轴,其具有近端和远侧部分,所述近端附接到所述切割元件,推进器附接到所述远侧部分;和(ii)桨叶,其附接到所述切割元件。在一个实施例中,切割元件具有杯状表面,所述杯状表面构造用于在所述杯状表面沿向远侧方向移动时,沿向远侧方向重新导向由切割边缘切割的组织。在一个实施例中,用于在组织收集室中向远侧推进流体的部件选自包括以下部件的组:(i)驱动轴,其具有近端和远侧部分,所述近端附接到所述切割元件的杯状表面,推进器附接到所述远侧部分;(ii)桨叶,其附接到所述切割元件的杯状表面。
在一个实施例中,用于在组织收集室中向远侧推进流体的部件是驱动轴,其具有近端和远侧部分,所述近端附接到所述切割元件,推进器附接到所述远侧部分。在一个实施例中,所述推进器设置在所述开口的远侧,并且设置在所述收集室的远端的近侧。在一个实施例中,推进器紧接地设置在所述开口的远侧。在一个实施例中,所述推进器设置在所述收集室的远侧半部中。在一个实施例中,驱动轴的近端附接到切割元件的杯状表面,所述杯状表面构造用于在杯状表面沿向远侧方向移动时,沿向远侧方向重新导向由切割边缘切割的组织。
在一个实施例中,用于在组织收集室中向远侧推进流体的部件为桨叶,其附接到切割元件。在一个实施例中,桨叶为以螺旋结构扭绞的金属丝。在一个实施例中,金属丝具有矩形横截面。在一个实施例中,金属丝的厚度为0.002到0.020英寸(0.0051到0.051cm)。在一个实施例中,金属丝的宽度为0.010到0.075英寸(0.025到0.19cm)。在一个实施例中,桨叶的金属丝宽度为收集室内径的百分之20到95。在一个实施例中,桨叶的纵向长度为收集室的纵向长度的至少百分之50。在一个实施例中,桨叶的纵向长度为收集室的纵向长度的至少百分之70。在一个实施例中,组织收集室包括排放孔。在一个实施例中,组织收集室包括10到200个排放孔。在一个实施例中,排放孔的直径为25到200微米。在一个实施例中,桨叶附接到切割元件的杯状表面,所述杯状表面构造用于在所述杯状表面沿向远侧方向移动时,沿向远侧方向重新导向由所述切割边缘切割的组织。
在一个实施例中,收集室包括在远端的部分,其可打开来去除切割的材料和颗粒。在一个实施例中,切割元件可在存储位置和切割位置之间相对于开口移动。
本发明提供一种在粥样硬化斑块切除导管中再循环流体的方法,包括:提供一种粥样硬化斑块切除导管,所述粥样硬化斑块切除导管包括:主体,其具有开口;可旋转轴,其联接到所述主体;组织收集室,其联接到所述主体,并且设置在切割元件的远侧,所述组织收集室具有排放孔;切割元件,其联接到所述可旋转轴,所述切割元件具有切割边缘;和使流体通过所述排放孔移出组织收集室,以在组织收集室内部形成负压,并且该负压使流体通过所述导管的主体的开口进入所述组织收集室中。在一个实施例中,所述导管包括管腔,其构造用于将流体导向到所述组织收集室中。在一个实施例中,所述导管包括用于在所述组织收集室中向远侧推进流体的部件,所述部件选自包括以下部件的组:(i)驱动轴,其具有近端和远侧部分,所述近端附接到所述切割元件,推进器附接到所述远侧部分;和(ii)桨叶,其附接到所述切割元件。
本发明提供一种从身体管腔去除材料的方法,所述方法包括:提供一种粥样硬化斑块切除导管,所述粥样硬化斑块切除导管包括:主体,其具有开口;可旋转轴,其联接到所述主体;组织收集室,其联接到所述主体,并且设置在切割元件的远侧;切割元件,其联接到所述可旋转轴,所述切割元件具有切割边缘;和管腔,其构造用于将流体导向到所述组织收集室中;将所述导管放置到身体管腔中;和在身体管腔中移动所述导管来将所述切割元件与身体管腔中的材料接触。在一个实施例中,所述导管沿向远侧方向移动,以使切割边缘与身体管腔中的材料接触。在一个实施例中,在切割元件处于存储位置中的情况下,将导管放置在身体管腔中,并且在所述切割元件处于切割位置中的情况下,移动所述导管来与材料接触。在一个实施例中,身体管腔为血管。
本发明提供一种从身体管腔去除材料的方法,所述方法包括:提供一种粥样硬化斑块切除导管,所述粥样硬化斑块切除导管包括:主体,其具有开口;可旋转轴,其联接到所述主体;组织收集室,其联接到所述主体,并且设置在切割元件的远侧;切割元件,其联接到所述可旋转轴,所述切割元件具有切割边缘;和用于在所述组织收集室中向远侧推进流体的部件,所述部件选自包括以下部件的组:(i)驱动轴,其具有近端和远侧部分,所述近端附接到所述切割元件,推进器附接到所述远侧部分;和(ii)桨叶,其附接到所述切割元件;将所述导管放置到身体管腔中;和在身体管腔中移动所述导管来使所述切割元件与身体管腔中的材料接触。在一个实施例中,所述导管沿向远侧方向移动,以使切割边缘与身体管腔中的材料接触。在一个实施例中,在切割元件处于存储位置中的情况下,将导管放置在身体管腔中,并且在所述切割元件处于切割位置中的情况下,移动所述导管来与材料接触。在一个实施例中,身体管腔为血管。
本发明提供一种改进的粥样硬化斑块切除导管,其具有用于将由切割元件产生的颗粒导向到组织收集室中的结构特征。还提供了将被切割的材料从血管管腔导向到组织收集室的方法。所述切割元件具有围绕杯状表面的锋利的切割边缘。被切割的材料由所述杯状表面和流体流导向到所述组织收集室中。
参照图1到4,显示了粥样硬化斑块切除导管2,其具有切割元件4,所述切割元件4用于从血流管腔例如血管切割材料。切割元件4可在存储位置(图2)和切割位置(图3)之间在导管2的主体8中相对于开口6移动。切割元件4相对于开口6向外移动,以使元件4的一部分通过开口6从主体8向外延伸。在一个实施例中,切割元件4可相对于主体8和开口6设置成使得切割元件4的小于90度的部分露出来切割组织。在其它实施例中,更大部分的切割元件4可露出而不偏离本发明的多个方面。
导管2的远端在切割元件4处于存储位置的情况下靠近血管的处理位置设置。然后在切割元件4处于工作或切割位置中的情况下,将导管2向远侧移动通过血管,如下面进一步详细所述。当导管2在切割元件4处于工作或切割位置中的情况下移动通过血管时,组织材料由切割元件4切割,并且被导向到设置在切割元件4远侧的组织收集室12中。组织收集室12可略微细长,以容纳已经切割的组织。
为了通过开口6露出切割元件4,切割元件4从存储位置向近侧移动,以使切割元件4上的凸轮表面14与导管2的主体8上的斜坡16接合。凸轮表面14和斜坡16之间的相互作用使切割元件4移动到切割位置,并且还使端头18偏转,所述偏转倾向于朝向待切割组织移动切割元件4。
切割元件4具有杯状表面24,其将由切割边缘22切割的组织导向到组织收集室12中。切割边缘22可处于切割元件4的径向外边缘23处。在一些实施例中,对于从纵轴线LA到切割边缘22的外径的距离的至少一半而言,杯状表面24可以是没有通孔、齿、翅片或其它结构特征的光滑连续的表面,而这些通孔、齿、翅片或其它结构特征会破坏表面24的光滑属性。在一些实施例中,杯状表面24还可以在整个相对于纵轴线LA至少300度的区域没有任何这样的结构特征。在其它实施例中,杯状表面可具有有限数量的通孔、齿、翅片或其它结构特征,如下面进一步详细描述的。一个或多个突起元件26可从杯状表面24向外延伸,图4显示了两个突起元件26。突起元件26是材料构成的小楔,其从杯状表面24相对陡峭地凸起。突起元件26有助于通过向硬组织或斑块施加相对钝的冲击力来破坏硬组织或斑块,因为使用切割边缘22切割这样的组织可能不是很有效,并且这样的硬组织条可能不够柔软来由杯状表面24重新导向到组织收集室12中。全部突起元件26占据杯状表面24的较小的部分。通过以该方式设置突起元件26的尺寸和位置,突起元件26不会妨碍切割元件4的杯状表面24的切割和将大条组织重新导向到组织收集室的能力,同时仍能提供使用突起元件26破碎硬组织和斑块的能力。
切割元件4联接到轴20,所述轴20延伸穿过导管2的管腔21。导管2联接到示例性的切割器驱动装置5。切割器驱动装置5包括马达11、电源15(例如一个或多个电池)、微开关(未示出)、壳体17(如图所示,壳体的上半部被去除)、杆13和用于将轴20连接到驱动马达11的连接组件(未示出)。切割器驱动装置5可用作用于使用者操纵导管2的手柄。当杆13被致动来闭合微开关时,杆13将电源15电连接到马达11,由此使切割元件4转动。当轴20旋转时,切割元件4围绕纵轴线LA旋转。切割元件4以约1到160,000rpm的速度旋转,但是可以任何其它适当的速度旋转,取决于特定应用。类似于导管2的导管的进一步描述可见于授予Patel等人的名称为“DebulkingCatheter”的美国专利申请公开号US 2002/0077642A1,其内容在此以引用的方式并入本文中。
使用中,导管2以相对大的条从血管壁切割较柔软的斑块,杯状表面24将这些条导向通过开口6进入组织收集室12中。在一些情况下,在较硬的或钙化斑块的去除过程中产生的较小的颗粒可由杯状表面24朝向开口6导向,并且在一些情况下也可沿与旋转的切割元件外边缘23相切的方向被导向经过开口6,在该情况下没有收集到组织收集室12中。
现在参照图5,显示了导管2A,其中,导管2A的相同或相似的附图标记指代管2的相同或相似的结构,并且与导管2的相同或相似结构特征相关的所有讨论可等同应用到这里,除非另外说明。与导管2相比较,导管2A具有改进的材料收集能力,并且另外包括切割元件4中的管腔4A、连接轴20中的管腔20A、切割驱动器5处的旋转接头(未示出)、流体源(未示出)和收集室12的壁中的排放孔31。切割元件4和连接轴20通过粘合、焊接、模压、压装配合、衬垫机械密封或其它方式附接,以在管腔4A和20A之间形成防渗漏流体连接。切割器驱动器5处的旋转接头以类似方式附接到连接轴20和流体源,以在流体源和旋转连接轴20之间形成防渗漏流体连接。在一些实施例中,管腔直径和长度的尺寸使得在50psi(345千帕)下允许0.5到50cc/min的流体流动速率,包括0.5,1,2,5,10,20,或50cc/min,或其它流动速率。在其它实施例中,这些流动速率在1,5,10,20,100或150psi(6.9,35,69,140,690或1000千帕)的驱动压力下或在其之间的压力下获得。
排放孔31允许流体流出组织收集室12的内部68,而不使大量的材料颗粒从其通过。在一个实施例中,排放孔直径为50微米。在其它实施例中,排放孔直径为25到200微米,包括25,35,65,80,100,150或200微米。排放孔31的数量、间距和分布可改变。在各实施例中,可设计10到200个排放孔,并且排放孔的数量可以为从10到200,包括10,20,30,50,75,100或200。排放孔可在组织收集室12的外表面上非均匀或均匀分布。在一个实施例中,大于一半的孔分布在组织收集室12的外表面的近侧半部上,以使得当组织收集室的排放孔由颗粒和碎片堵塞时,仍维持从组织收集室12的内部68的流动。在另一个实施例中,为了促使流体优先流出排放孔31而不是流出开口6,经过全部排放孔的流体的总液压阻力小于经过开口6的流体的液压阻力。
操作中,导管2A在切割元件4通过开口6露出的情况下前进通过血管V。切割元件4将粥样硬化斑块材料M的大碎片F从血管V的管腔表面LS分离,并且切割元件4的杯状表面24将所述碎片导向通过开口6进入组织收集室12的内部68中。流体源在切割元件4旋转之前、旋转过程中或旋转之后,或在切割元件旋转之前、旋转过程中或旋转之后的任意组合时间推动加压流体(例如生理食盐水)通过管腔20A,4A。流体沿箭头A的方向离开切割元件4的管腔4A,流入组织收集室12的内部68中,并且流出排放孔31。由作用在材料M上的切割元件4产生的小颗粒P由流体流运送到组织收集室12的内部68的远侧区域68d中。
参照图6,显示了另一种导管2B,其中,导管2B的相同或相似的附图标记指代管2的相同或相似的结构,并且与导管2的相同或相似结构特征相关的所有讨论可等同应用到这里,除非另外说明。与导管2相比较,导管2B具有改进的材料收集能力,并且另外包括管7、流体源(未示出)和收集室12的壁中的排放孔31。管7在切割器驱动器5附近通过防渗漏流体连接,例如衬垫机械密封,附接到流体源。在一些实施例中,流体源仅在切割器4旋转时例如通过阀提供流动,以防止过多的流体注入患者中。流体源可在切割元件4旋转之前、旋转过程中或旋转后,或在切割元件旋转之前、旋转过程中或旋转之后的任意组合时间提供流动。在其它实施例中,流体包含不透射线物质,例如造影剂,以便于组织收集室中的材料量可视化。管7的远端可沿从朝向组织收集室12的侧壁到朝向组织收集室12的最远端这些方向范围内的任何方向取向。在一个实施例中,管7的远端朝向组织收集室12的内部68的远侧区域68d取向。在其它实施例中,管7具有单通阀,其允许向远侧通过所述管的流动,但是防止向近侧通过所述管的流动,以防止血液或碎片进入管7中,并且防止可能的对管7管腔的阻塞。在一些实施例中,管7的管腔直径和长度的尺寸使得允许50psi(345千帕)的驱动压力下0.5到50cc/min的流体流动速率,包括0.5,1,2,5,10,20,或50cc/min,或其它流动速率。在其它实施例中,这些流动速率在1,5,10,20,100或150psi(6.9,35,69,140,690或1000千帕)的驱动压力下或在其之间的压力下获得。排放孔31具有如上面针对导管2A所述的结构和功能特性。
在导管2B的另一个实施例中,流体通过导管2的管腔21注入,而不是通过管7的管腔注入。在该实施例中,流体通道(未示出)可设置在斜坡16中,以使流体向远侧流动通过斜坡16,并且从斜坡16离开进入组织收集室12的内部68中。
操作中,导管2B在切割元件4通过开口6露出的情况下前进通过血管V。切割元件4将粥样硬化斑块材料M的大碎片F从血管V的管腔表面LS分离,并且切割元件4的杯状表面24将所述碎片导向通过开口6进入组织收集室12的内部68中。流体源在切割元件4旋转之前、旋转过程中或旋转之后,或在切割元件旋转之前、旋转过程中或旋转之后的任意组合时间推动加压流体(例如生理食盐水)通过管7。在一些实施例中,流体包含不透射线染料,并且端头中的斑块量可视化。流体沿箭头B的方向离开管7的管腔,流入组织收集室12的内部68中,并且流出排放孔31。由作用在材料M上的切割元件4产生的小颗粒P由流体流运送到组织收集室12的内部68的远侧区域68d中。
参照图7,显示了另一种导管2C,其中,导管2C的相同或相似的附图标记指代管2的相同或相似的结构,并且与导管2的相同或相似结构特征相关的所有讨论可等同应用到这里,除非另外说明。与导管2相比较,导管2C具有改进的材料收集能力,并且另外包括切割元件4中的管腔4C、连接轴20中的管腔20C和孔20D、推进器9、导管2中的入口孔32和收集室12的壁中的排放孔31。切割元件4和连接轴20通过粘合、焊接、模压、压装配合、衬垫机械密封或其它方式附接,以在管腔4C和20C之间形成防渗漏流体连接。孔32允许流体从血管V的管腔L传送到管腔21中,孔20D允许流体从管腔21传送到管腔20C中。在一些实施例中,管腔直径和长度的尺寸允许在50psi(345千帕)的驱动压力下0.5到50cc/min的流体流动速率,包括0.5,1,2,5,10,20,或50cc/min,或其它流动速率。在其它实施例中,这些流动速率在1,5,10,20,100或150psi(6.9,35,69,140,690或1000千帕)的驱动压力下或在其之间的压力下获得。推进器9通过粘合剂粘合、焊接、机械互锁或其它方式牢固地附接到连接轴20。
参照图7A,推进器9由金属、塑料或其它材料构造,包括但不限于不锈钢、镍钛合金、聚甲醛(可以商标商购获得)、聚醚嵌段酰胺(可以商标商购获得)、聚酰胺、尼龙12、聚酯或其它材料。推进器可以是通过焊接、粘合剂粘合或其它方式附接到连接轴20的单独构造的部件,或可由所述轴一体形成。在一些实施例中,推进器包括1到10个或更多个螺旋圈,包括1,2,3,4,6,8,或10个螺旋圈(图7A中示出四个螺旋圈9e)。可设计10到75度的螺距角9a,包括10,20,30,45,60或75度,螺距9b沿推进器长度可相同或变化。在一些实施例中,推进器9的外径和导管2的内径之间的间隙9d可为0.000到0.010英寸(0.000到0.025cm),包括0.000,0.001,0.002,0.003,0.004,0.007或0.010英寸(0.000,0.0025,0.0051,0.0076,0.010,0.018,或0.025cm)或为在其之间的值。在其它实施例中,在推进器9的外径和导管2的内径之间可以是过盈配合或负间隙9d,大小为0.0005到0.002英寸(0.0013到0.0051cm),包括0.0005,0.001或0.002英寸(0.0013,0.0025或0.0051cm),或在其之间的值。在其它实施例中,推进器9的尺寸和管腔21的直径可改变,以当推进器以1000,2000,4000,8000,16000或24000RPM或以在其之间的旋转速度旋转时,产生0.5到50cc/min的流体流动速率,包括0.5,1,2,5,10,20,或50cm/min,或其它流动速率。排放孔31具有如上面针对导管2A所述的结构和功能特性。
操作中,导管2C在切割元件4通过开口6露出的情况下前进通过血管V。切割元件将粥样硬化斑块材料M的大碎片F从血管V的管腔表面LS分离,并且切割元件4的杯状表面24将所述碎片导向通过开口6进入组织收集室12的内部68中。在切割元件4旋转过程中,沿由箭头D指示的方向旋转的推进器9将流体(例如血液)从血管的管腔L抽吸通过孔32,进入管腔21中,为流体加压,并且将加压的流体推动通过孔20D、管腔20C和管腔4C。流体沿箭头C的方向离开切割元件4的管腔4C,流入组织收集室12的内部68中,并且流出排放孔31。由作用在材料M上的切割元件4产生的小颗粒P由流体流运送到组织收集室12的内部68的远侧区域68d中。
可使用切割元件40(参见图8和8A)代替导管2,2A,2B,2C或2D中的任一个的切割元件4。切割元件40类似于切割元件4,其中,切割元件40的相同或相似的附图标记指代切割元件4的相同或相似的结构,并且与切割元件4的所述相同或相似结构特征相关的全部讨论可等同应用到这里,除非另外说明。与切割元件4相比较,切割元件40另外包括一个或多个通道42和一个或多个孔44。在切割元件40沿方向E的旋转过程中,流体(例如血液)在切割元件40的外边缘23处进入通道42中,并且向远侧通过孔44离开。通道42和孔44可通过钻孔、放电加工(EDM)或其它方式构造在切割器40中。在一个实施例中,切割元件40以2件制成,一个具有在其中切割出的通道,另一个具有切割边缘22、杯状表面24、突起元件26(如果使用)和形成于其中的孔44,所述两件通过焊接、软钎焊、硬钎焊、粘合剂粘合、机械互锁或其它方式顺序地联接在一起。在一些实施例中,孔44没有沿切割元件40的轴线LA设置。通道和孔的数量、通道宽度42W、通道长度42L和孔44直径可改变,以在切割元件40以1000,2000,4000,8000,16000或24000RPM或其间的转速旋转时,产生0.5到50cc/min的流体流动速率,包括0.5,1,2,5,10,20或50cc/min,或其它流动速率。
如之前例如针对导管2A描述的,操作中,切割元件40在用于血管V中的过程中沿箭头E的方向旋转。切割元件40将粥样硬化斑块材料M的大碎片F从血管V的管腔表面LS分离,并且切割元件4的杯状表面24将所述碎片通过开口6导向进入组织收集室12的内部68中。在切割元件的旋转过程中,沿由箭头E指示的方向旋转的切割元件40将来自血管V的管腔L的流体(例如血液)推动到通道42中,进入孔44内。流体沿大体上纵轴线LA的方向离开切割元件40的孔44,流入组织收集室12的内部68中,并且流出排放孔31。由作用在材料M上的切割元件40产生的小颗粒P由流体流运送到组织收集室12的内部68的远侧区域68d中。
参照图9,显示了另一种导管2D,其中导管2D的相同或相似的附图标记指代管2的相同或相似的结构,并且与导管2的相同或相似结构特征相关的所有讨论可等同应用到这里,除非另外说明。与导管2相比较,导管2D具有改进的材料收集能力,并且另外包括驱动轴33和一个或多个推进器34。在各实施例中,驱动轴33和推进器34可由例如不锈钢、钴-铬-镍-钼-铁合金(可以商标商购获得)等金属,或其它金属,或例如聚酯、聚酰胺、尼龙12、液晶聚合物等聚合物或其它聚合物构造。在一些实施例中,通过焊接、硬钎焊、软钎焊、包覆模制、机械互锁、粘合剂粘合或其它附接方式,将驱动轴33附接到切割元件4的杯状表面24和将推进器34附接到驱动轴33。在一个实施例中,驱动轴33沿纵轴线LA附接到切割元件4的杯状表面24。驱动轴33具有的柔性足够在切割元件的轴线LA和收集室12的纵轴线LACC之间弯曲。在一个实施例中(图9),驱动轴33的长度足够将推进器34靠近收集室12的远端设置。在另一个实施例中(图10A),驱动轴的长度仅足够将推进器34紧接着开口6的远侧设置。驱动轴33可以具有在这两个极端位置处或之间的任何长度。推进器34取向为沿向远侧方向推进流体(例如血液)。推进器34的螺距可改变,以当推进器以1000,2000,4000,8000,16000或24000RPM或以在其之间的旋转速度旋转时,产生0.5到50cc/min的流体流动速率,包括0.5,1,2,5,10,20,或50cm/min,或其它流动速率。排放孔31具有如上面针对导管2A所述的结构和功能特性。
操作中,导管2D在切割元件4通过开口6露出的情况下前进通过血管V。切割元件4将粥样硬化斑块材料M的大碎片F从血管V的管腔表面LS分离,并且切割元件4的杯状表面24将所述碎片导向通过开口6进入收集室12的内部68中。推进器34在组织收集室12的内部68中向远侧推进流体,并且将流体通过排放孔31排出,由此使流体(例如血液)通过开口6抽吸入收集室12中。进入开口6的流体流将由作用在材料M上的切割元件4产生的小颗粒P运送到收集室12的内部68的远侧区域68d中。
在导管2D的另一个实施例中,桨叶附接到切割元件4的杯状表面24,而不是将驱动轴33和推进器34附接到杯状表面24。桨叶的一些实施例示出在图9A,9B和9C中,并且分别以桨叶35A,35B和35C标示。桨叶35A,35B,35C在切割器4处于存储位置中的情况下示出。桨叶可由金属丝构成,所述金属丝在一些实施例中具有矩形横截面。金属丝扭绞为图中所示的螺旋结构。桨叶35A,35B和35C使组织收集室12内部68中的流体在切割元件4旋转过程中向远侧移动。在一些实施例中,金属丝宽度(金属丝的在垂直于导管纵轴线的平面中的部分之间的最大距离)、长度和厚度以及螺旋的螺距可改变,以当推进器以1000,2000,4000,8000,16000或24000RPM或以在其之间的旋转速度旋转时,产生0.5到50cc/min的流体流动速率,包括0.5,1,2,5,10,20,或50cm/min,或其它流动速率。在一些实施例中,金属丝厚度可为0.002到0.020英寸(0.0051到0.051cm),包括0.002,0.003,0.004,0.005,0.007,0.009,0.011,0.015或0.020英寸(0.0051,0.0076,0.010,0.013,0.018,0.023,0.028,0.038或0.051cm),金属丝宽度可以是0.010到0.075英寸(0.025到0.19cm),包括0.010,0.015,0.020,0.025,0.030,0.040,0.050或0.075英寸(0.025,0.038,0.051,0.064,0.076,0.10,0.13或0.19cm),或在其之间的厚度、金属丝宽度或在其之间的厚度和金属丝宽度。
在一个示例性实施例中,图9A示出桨叶35A,其由已经扭绞为约与组织收集室12一样长的螺旋的矩形横截面金属丝构成,金属丝宽度D1为收集室内径的40%,并且在整个桨叶长度上具有均匀的螺距长度P1。在另一个示例性实施例中,图9B示出桨叶35B,其由已经扭绞为组织收集室12的长度的60%的螺旋的矩形横截面金属丝构成,所述桨叶35B在桨叶近侧部分上具有的金属丝宽度D2为收集室内径的40%,在桨叶远侧部分上具有的金属丝宽度D3为收集室内径的80%,并且其在桨叶长度上具有均匀的螺距长度P2。应可预期,其它实施例可具有3个或更多个不同的金属丝宽度,或金属丝宽度可在桨叶35B的至少一些部分上连续改变。而且,可设计金属丝宽度为组织收集室的内径的20%到组织收集室的内径的95%。图9C示出桨叶35C,其由已经扭绞为组织收集室12的长度的70%的螺旋的矩形横截面金属丝构成,所述桨叶35C在整个桨叶长度上具有的金属丝宽度D4为收集室内径的30%,在桨叶近侧部分上具有螺距长度P3,在桨叶远侧部分上具有螺距长度P4。应可预期,其它实施例可具有3个或更多个不同的螺距长度,或螺距长度可在桨叶35C的至少一些部分上连续改变。在其它实施例中,金属丝宽度和螺距长度可都在桨叶长度上连续或离散地变化。
可任选地,在一些实施例中,导管2,2A,2B或2C可另外包括驱动轴33和推进器34。在其它实施例中,导管2,2A,2B或2C可另外包括桨叶35A,35B或35C。
操作中,在切割元件4通过开口6露出的情况下,配备有桨叶35A,35B或35C而不是轴33和推进器34的导管2D前进通过血管V。切割元件4将粥样硬化斑块材料M的大碎片F从血管V的管腔表面LS分离,并且切割元件4的杯状表面24将所述碎片导向通过开口6进入收集室12的内部68中。桨叶35A,35B或35C在组织收集室12的内部68中向远侧推进流体,并且将流体通过排放孔31排出,由此使流体(例如血液)通过开口6抽吸入收集室12中。进入开口6的流体流将由作用在材料M上的切割元件4产生的小颗粒P运送到收集室12的内部68的远侧区域68d中。桨叶35也将碎片F运送到收集室12的内部68的远侧区域68d中。
在另一个实施例中,通过在收集室12的远端处设置开口,然后旋转桨叶34或桨叶35以由此排出碎屑,来将碎片F和颗粒P从收集室12的内部68去除。对在收集室12的远端处设置有开口的导管的进一步的描述可见于授予Simpson等人的名称为“Debulking Catheter andMethods”的美国专利申请公开号US 2005/0222663A1中,其内容在此以引用的方式并入本文中。参见[0117]到[0146]段。其它实施例中,导管2,2A,2B或2C可另外包括轴33和推进器34或桨叶35A,35B或35C,并且收集室12的内部可如上面针对导管2D所述地清除碎屑。
在导管2A,2B,2C或2D的一些实施例中,可建立流体再循环回路。这在血管中向远侧流动全部或几乎全部阻塞的情况下特别期望(参见图10A),其中,例如材料M完全堵塞材料去除导管远侧的血管。为了建立流体再循环回路,流出排放孔31的流体的流动速率必须超过通过管腔4A(导管2A)、通过管7(导管2B)、通过管腔4C(导管2C)、通过切割元件40的孔44或通过这些结构的组合(在使用的情况下)进入收集器12的内部68中的流体的体积。当出现该流动状况时,将在收集室12的内部68中建立负压,流体将通过开口6流入收集室12中,由此将由切割元件产生的颗粒P抽吸入收集室12的内部68中(图10A和10B)。
除了用于血管中,可设想本发明可用于去除其它血流管腔例如天然或人造植入物、支架植入物、吻合口、瘘管或其它血流管腔中的堵塞物。
上面的描述和附图出于描述本发明的实施例而提供,不旨在以任何方式限制本发明的范围。对本领域技术人员显而易见的是,可进行各种修改和改变而不偏离本发明的精神或范围。因而,本发明旨在覆盖落在所附权利要求及其等同方案的范围内的本发明的所有修改形式和变形形式。而且,虽然上面已经针对一些实施例描述了对材料和结构的选择,但是本领域的普通技术人员将理解,所述的材料和结构可适用于全部实施例。
Claims (59)
1.一种粥样硬化斑块切除导管,包括:
主体,所述主体具有开口;
可旋转轴,所述可旋转轴联接到所述主体;
组织收集室,所述组织收集室联接到所述主体,并且设置在切割元件的远侧;
切割元件,所述切割元件联接到所述可旋转轴,所述切割元件具有切割边缘;和
管腔,所述管腔构造用于将流体导向到所述组织收集室中。
2.根据权利要求1所述的导管,其中,所述管腔将流体沿向远侧方向导向到所述组织收集室中。
3.根据权利要求1所述的导管,其中,所述切割元件具有杯状表面,所述杯状表面构造用于在所述杯状表面沿向远侧方向移动时,沿向远侧方向重新导向由所述切割边缘切割的组织。
4.根据权利要求3所述的导管,其中,所述管腔在所述切割元件的杯状表面上具有远侧开口。
5.根据权利要求4所述的导管,其中,所述管腔包括在所述切割元件中的第一管腔部分和在所述可旋转轴中的第二管腔部分。
6.根据权利要求4所述的导管,其中,所述远侧开口设置在所述切割元件的纵轴线处。
7.根据权利要求3所述的导管,其中,所述管腔具有远侧开口,并且所述远侧开口不设置在所述切割元件的杯状表面上。
8.根据权利要求7所述的导管,其中,所述远侧开口与所述切割元件的杯状表面相邻设置。
9.根据权利要求1所述的导管,其中,将流体提供到所述管腔的流体源附接到所述导管的近侧部分。
10.根据权利要求9所述的导管,其中,由所述流体源提供的流体为食盐水。
11.根据权利要求9所述的导管,其中,由所述流体源提供的流体包含不透射线物质。
12.根据权利要求3所述的导管,其中,所述管腔的近侧开口设置在所述导管的远侧部分处,但是在所述切割元件的杯状表面的近侧。
13.根据权利要求12所述的导管,其中,所述近侧开口设置在所述可旋转轴上。
14.根据权利要求13所述的导管,其中,所述可旋转轴包括所述管腔的两个或更多个近侧开口。
15.根据权利要求13所述的导管,其中,所述可旋转轴包括在所述近侧开口近侧的推进器,当所述可旋转轴旋转时,所述推进器推动流体进入所述近侧开口中。
16.根据权利要求15所述的导管,其中,所述推进器具有1到10个螺旋圈。
17.根据权利要求12所述的导管,其中,所述管腔在所述切割元件的杯状表面上具有远侧开口。
18.根据权利要求17所述的导管,其中,所述远侧开口设置在所述切割元件的纵轴线处。
19.根据权利要求1所述的导管,其中,所述管腔的近侧开口设置在所述切割元件上。
20.根据权利要求19所述的导管,其中,所述近侧开口设置在所述切割元件的外边缘处。
21.根据权利要求20所述的导管,其中,所述切割元件具有杯状表面,所述杯状表面构造用于在所述杯状表面沿向远侧方向移动时,沿向远侧方向重新导向由所述切割边缘切割的组织,所述管腔在所述切割元件的杯状表面上具有远侧开口。
22.根据权利要求21所述的导管,其中,所述远侧开口设置在所述切割元件的纵轴线处。
23.根据权利要求1所述的导管,其中,所述组织收集室包括排放孔。
24.根据权利要求23所述的导管,其中,所述组织收集室包括10到200个排放孔。
25.根据权利要求23所述的导管,其中,所述排放孔的直径为25到200微米。
26.根据权利要求1所述的导管,其中,所述切割元件能相对于所述开口在存储位置和切割位置之间移动。
27.一种粥样硬化斑块切除导管,包括:
主体,所述主体具有开口;
可旋转轴,所述可旋转轴联接到所述主体;
组织收集室,所述组织收集室联接到所述主体,并且设置在切割元件的远侧;
切割元件,所述切割元件联接到所述可旋转轴,所述切割元件具有切割边缘;和
用于在所述组织收集室中向远侧推进流体的部件,所述部件选自包括以下部件的组:(i)驱动轴,所述驱动轴具有近端和远侧部分,所述近端附接到所述切割元件,推进器附接到所述远侧部分;和(ii)桨叶,所述桨叶附接到所述切割元件。
28.根据权利要求27所述的导管,其中,所述切割元件具有杯状表面,所述杯状表面构造用于在所述杯状表面沿向远侧方向移动时,沿向远侧方向重新导向由所述切割边缘切割的组织。
29.根据权利要求28所述的导管,其中,所述用于在所述组织收集室中向远侧推进流体的部件选自包括以下部件的组:(i)驱动轴,所述驱动轴具有近端和远侧部分,所述近端附接到所述切割元件的杯状表面,推进器附接到所述远侧部分;和(ii)桨叶,所述桨叶附接到所述切割元件的杯状表面。
30.根据权利要求27所述的导管,其中,所述用于在所述组织收集室中向远侧推进流体的部件是驱动轴,所述驱动轴具有近端和远侧部分,所述近端附接到所述切割元件,推进器附接到所述远侧部分。
31.根据权利要求30所述的导管,其中,所述推进器设置在所述开口的远侧,并且设置在所述组织收集室的远端的近侧。
32.根据权利要求31所述的导管,其中,所述推进器紧接地设置在所述开口的远侧。
33.根据权利要求31所述的导管,其中,所述推进器设置在所述组织收集室的远侧半部中。
34.根据权利要求30所述的导管,其中,所述驱动轴的近端附接到所述切割元件的杯状表面,所述杯状表面构造用于当所述杯状表面沿向远侧方向移动时,沿向远侧方向重新导向由所述切割边缘切割的组织。
35.根据权利要求27所述的导管,其中,所述用于在所述组织收集室中向远侧推进流体的部件为附接到所述切割元件的桨叶。
36.根据权利要求35所述的导管,其中,所述桨叶为以螺旋结构扭绞的金属丝。
37.根据权利要求36所述的导管,其中,所述金属丝具有矩形横截面。
38.根据权利要求36所述的导管,其中,所述金属丝的厚度为0.002到0.020英寸(0.0051到0.051cm)。
39.根据权利要求36所述的导管,其中,所述金属丝的宽度为0.010到0.075英寸(0.025到0.19cm)。
40.根据权利要求36所述的导管,其中,所述桨叶的金属丝宽度为所述组织收集室的内径的百分之20到95。
41.根据权利要求35所述的导管,其中,所述桨叶的纵向长度为所述组织收集室的纵向长度的至少百分之50。
42.根据权利要求35所述的导管,其中,所述桨叶的纵向长度为所述组织收集室的纵向长度的至少百分之70。
43.根据权利要求27所述的导管,其中,所述组织收集室包括排放孔。
44.根据权利要求43所述的导管,其中,所述组织收集室包括10到200个排放孔。
45.根据权利要求43所述的导管,其中,所述排放孔的直径为25到200微米。
46.根据权利要求35所述的导管,其中,所述桨叶附接到所述切割元件的杯状表面,所述杯状表面构造用于当所述杯状表面沿向远侧方向移动时,沿向远侧方向重新导向由所述切割边缘切割的组织。
47.根据权利要求27所述的导管,其中,所述组织收集室包括在远端处的一部分,所述在远端处的一部分可打开来去除切割的材料和颗粒。
48.根据权利要求27所述的导管,其中,所述切割元件能相对于所述开口在存储位置和切割位置之间移动。
49.一种在粥样硬化斑块切除导管中再循环流体的方法,包括:
提供一种粥样硬化斑块切除导管,所述粥样硬化斑块切除导管包括:
主体,所述主体具有开口;
可旋转轴,所述可旋转轴联接到所述主体;
组织收集室,所述组织收集室联接到所述主体,并且设置在切割元件的远侧,所述组织收集室具有排放孔;
切割元件,所述切割元件联接到所述可旋转轴,所述切割元件具有切割边缘;和
通过所述排放孔将流体移出所述组织收集室,以在所述组织收集室内部形成负压,并且该负压使流体通过所述导管的主体的开口进入所述组织收集室中。
50.根据权利要求49所述的方法,其中,所述导管包括管腔,所述管腔构造用于将流体导向到所述组织收集室中。
51.根据权利要求49所述的方法,其中,所述导管包括用于在所述组织收集室中向远侧推进流体的部件,所述部件选自包括以下部件的组:(i)驱动轴,所述驱动轴具有近端和远侧部分,所述近端附接到所述切割元件,推进器附接到所述远侧部分;和(ii)桨叶,所述桨叶附接到所述切割元件。
52.一种从身体管腔去除材料的方法,所述方法包括:
提供一种粥样硬化斑块切除导管,所述粥样硬化斑块切除导管包括:
主体,所述主体具有开口;
可旋转轴,所述可旋转轴联接到所述主体;
组织收集室,所述组织收集室联接到所述主体,并且设置在切割元件的远侧;
切割元件,所述切割元件联接到所述可旋转轴,所述切割元件具有切割边缘;和
管腔,所说管腔构造用于将流体导向到所述组织收集室;
将所述导管放置在所述身体管腔中;和
在所述身体管腔中移动所述导管,以将所述切割元件与所述身体管腔中的材料接触。
53.根据权利要求52所述的方法,其中,所述导管沿向远侧方向移动,以使所述切割边缘与所述身体管腔中的材料接触。
54.根据权利要求52所述的方法,其中,在所述切割元件处于存储位置中的情况下,将所述导管放置在所述身体管腔中,并且在所述切割元件处于切割位置中的情况下,移动所述导管来接触所述材料。
55.根据权利要求52所述的方法,其中,所述身体管腔为血管。
56.一种从身体管腔去除材料的方法,所述方法包括:
提供一种粥样硬化斑块切除导管,所述粥样硬化斑块切除导管包括:
主体,所述主体具有开口;
可旋转轴,所述可旋转轴联接到所述主体;
组织收集室,所述组织收集室联接到所述主体,并且设置在切割元件的远侧;
切割元件,所述切割元件联接到所述可旋转轴,所述切割元件具有切割边缘;和
用于在所述组织收集室中向远侧推进流体的部件,所述部件选自包括以下部件的组:(i)驱动轴,所述驱动轴具有近端和远侧部分,所述近端附接到所述切割元件,推进器附接到所述远侧部分;和(ii)桨叶,所述桨叶附接到所述切割元件;
将所述导管放置到所述身体管腔中;和
将所述导管在所述身体管腔中移动,以使所述切割元件与所述身体管腔中的材料接触。
57.根据权利要求56所述的方法,其中,所述导管沿向远侧方向移动,以使所述切割边缘与所述身体管腔中的材料接触。
58.根据权利要求56所述的方法,其中,在所述切割元件处于存储位置中的情况下,将所述导管放置在所述身体管腔中,和在所述切割元件处于切割位置中的情况下,移动所述导管来接触所述材料。
59.根据权利要求56所述的方法,其中,所述身体管腔为血管。
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103239272A (zh) * | 2012-11-03 | 2013-08-14 | 周建大 | 负压清创机 |
CN104869924A (zh) * | 2012-11-08 | 2015-08-26 | 柯惠有限合伙公司 | 具有可旋转切削件的组织移除导管 |
CN104869923A (zh) * | 2012-11-08 | 2015-08-26 | 柯惠有限合伙公司 | 包括操作控制机构的组织移除导管 |
CN109394308A (zh) * | 2013-08-23 | 2019-03-01 | 柯惠Lp公司 | 标本取出装置 |
Families Citing this family (75)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7713279B2 (en) | 2000-12-20 | 2010-05-11 | Fox Hollow Technologies, Inc. | Method and devices for cutting tissue |
US8328829B2 (en) | 1999-08-19 | 2012-12-11 | Covidien Lp | High capacity debulking catheter with razor edge cutting window |
US7708749B2 (en) | 2000-12-20 | 2010-05-04 | Fox Hollow Technologies, Inc. | Debulking catheters and methods |
US6299622B1 (en) | 1999-08-19 | 2001-10-09 | Fox Hollow Technologies, Inc. | Atherectomy catheter with aligned imager |
ATE499054T1 (de) | 2000-12-20 | 2011-03-15 | Fox Hollow Technologies Inc | Verkleinerungskatheter |
US8246640B2 (en) | 2003-04-22 | 2012-08-21 | Tyco Healthcare Group Lp | Methods and devices for cutting tissue at a vascular location |
US20070276419A1 (en) | 2006-05-26 | 2007-11-29 | Fox Hollow Technologies, Inc. | Methods and devices for rotating an active element and an energy emitter on a catheter |
US8784440B2 (en) | 2008-02-25 | 2014-07-22 | Covidien Lp | Methods and devices for cutting tissue |
US8548571B2 (en) | 2009-12-08 | 2013-10-01 | Avinger, Inc. | Devices and methods for predicting and preventing restenosis |
US9125562B2 (en) | 2009-07-01 | 2015-09-08 | Avinger, Inc. | Catheter-based off-axis optical coherence tomography imaging system |
KR101645754B1 (ko) | 2008-10-13 | 2016-08-04 | 코비디엔 엘피 | 카테테르 샤프트를 조작하는 장치 및 방법 |
WO2010129075A1 (en) | 2009-04-28 | 2010-11-11 | Avinger, Inc. | Guidewire support catheter |
CN102625673B (zh) | 2009-04-29 | 2014-12-24 | 泰科保健集团有限合伙公司 | 用于切割和研磨组织的方法及装置 |
AU2010248909B2 (en) | 2009-05-14 | 2013-03-21 | Covidien Lp | Easily cleaned atherectomy catheters and methods of use |
CA2763324C (en) | 2009-05-28 | 2018-10-23 | Avinger, Inc. | Optical coherence tomography for biological imaging |
EP2448502B1 (en) | 2009-07-01 | 2022-04-06 | Avinger, Inc. | Atherectomy catheter with laterally-displaceable tip |
AU2010326063B2 (en) | 2009-12-02 | 2013-07-04 | Covidien Lp | Methods and devices for cutting tissue |
JP5511107B2 (ja) | 2009-12-11 | 2014-06-04 | コヴィディエン リミテッド パートナーシップ | 改良された物質捕捉能率を有する物質除去デバイスおよび方法 |
US9119662B2 (en) * | 2010-06-14 | 2015-09-01 | Covidien Lp | Material removal device and method of use |
WO2014039099A1 (en) | 2012-09-06 | 2014-03-13 | Avinger, Inc. | Balloon atherectomy catheters with imaging |
US11382653B2 (en) | 2010-07-01 | 2022-07-12 | Avinger, Inc. | Atherectomy catheter |
JP2013531542A (ja) | 2010-07-01 | 2013-08-08 | アビンガー・インコーポレイテッド | 長手方向に移動可能なドライブシャフトを有するアテローム切除カテーテル |
WO2014039096A1 (en) | 2012-09-06 | 2014-03-13 | Avinger, Inc. | Re-entry stylet for catheter |
CA2815186C (en) | 2010-10-28 | 2015-12-29 | Covidien Lp | Material removal device and method of use |
AU2011326420B2 (en) | 2010-11-11 | 2014-11-27 | Covidien Lp | Flexible debulking catheters with imaging and methods of use and manufacture |
US9949754B2 (en) | 2011-03-28 | 2018-04-24 | Avinger, Inc. | Occlusion-crossing devices |
WO2012145133A2 (en) | 2011-03-28 | 2012-10-26 | Avinger, Inc. | Occlusion-crossing devices, imaging, and atherectomy devices |
US8992717B2 (en) | 2011-09-01 | 2015-03-31 | Covidien Lp | Catheter with helical drive shaft and methods of manufacture |
WO2013059363A1 (en) | 2011-10-17 | 2013-04-25 | Avinger, Inc. | Atherectomy catheters and non-contact actuation mechanism for catheters |
US9345406B2 (en) | 2011-11-11 | 2016-05-24 | Avinger, Inc. | Occlusion-crossing devices, atherectomy devices, and imaging |
CA2801744C (en) * | 2012-01-17 | 2015-10-13 | Covidien Lp | Material removal device and method of use |
EP2809098B1 (en) * | 2012-01-27 | 2019-03-06 | Kyocera Corporation | Mobile communication system, user terminal, and method at a processor of the user terminal |
EP2849661B1 (en) | 2012-05-14 | 2020-12-09 | Avinger, Inc. | Atherectomy catheters with imaging |
EP2849660B1 (en) | 2012-05-14 | 2021-08-25 | Avinger, Inc. | Atherectomy catheter drive assemblies |
EP2849636B1 (en) | 2012-05-14 | 2020-04-22 | Avinger, Inc. | Optical coherence tomography with graded index fiber for biological imaging |
JP6155516B2 (ja) * | 2012-08-02 | 2017-07-05 | ▲ホア▼▲ウェイ▼技術有限公司Huawei Technologies Co.,Ltd. | 端末、およびそのアクセス失敗後の処理方法 |
US9498247B2 (en) | 2014-02-06 | 2016-11-22 | Avinger, Inc. | Atherectomy catheters and occlusion crossing devices |
US11284916B2 (en) | 2012-09-06 | 2022-03-29 | Avinger, Inc. | Atherectomy catheters and occlusion crossing devices |
US9579157B2 (en) | 2012-09-13 | 2017-02-28 | Covidien Lp | Cleaning device for medical instrument and method of use |
WO2014093154A1 (en) | 2012-12-12 | 2014-06-19 | Covidien Lp | Tissue-removing catheter including urging mechanism |
WO2014093148A2 (en) | 2012-12-12 | 2014-06-19 | Covidien Lp | Tissue-removing catheter for body lumen |
JP6129988B2 (ja) | 2012-12-12 | 2017-05-17 | コヴィディエン リミテッド パートナーシップ | 偏心貫通カッター |
US9636139B2 (en) | 2012-12-12 | 2017-05-02 | Covidien Lp | Tissue-removing catheter with ball and socket deployment mechanism |
US9636138B2 (en) | 2012-12-12 | 2017-05-02 | Covidien Lp | Tissue-removing catheter including force-transmitting member for actuating a cutter housing |
JP6096318B2 (ja) | 2012-12-12 | 2017-03-15 | コヴィディエン リミテッド パートナーシップ | 組織除去カテーテルのためのカッター |
WO2014093068A1 (en) * | 2012-12-12 | 2014-06-19 | Covidien Lp | Tissue-removing catheter including screw blade and cutter driveshaft |
EP3202340A1 (en) | 2013-03-15 | 2017-08-09 | National University of Ireland Galway | A device suitable for removing matter from inside the lumen and the wall of a body lumen |
US11096717B2 (en) * | 2013-03-15 | 2021-08-24 | Avinger, Inc. | Tissue collection device for catheter |
WO2014143064A1 (en) | 2013-03-15 | 2014-09-18 | Avinger, Inc. | Chronic total occlusion crossing devices with imaging |
US10932670B2 (en) | 2013-03-15 | 2021-03-02 | Avinger, Inc. | Optical pressure sensor assembly |
WO2014204420A2 (en) * | 2013-06-22 | 2014-12-24 | Ihsan Tasci | System for excising anal fistula traces |
EP3019096B1 (en) | 2013-07-08 | 2023-07-05 | Avinger, Inc. | System for identification of elastic lamina to guide interventional therapy |
CN106102608B (zh) | 2014-02-06 | 2020-03-24 | 阿维格公司 | 旋切术导管和闭塞穿越设备 |
WO2015200702A1 (en) | 2014-06-27 | 2015-12-30 | Covidien Lp | Cleaning device for catheter and catheter including the same |
EP3166512B1 (en) | 2014-07-08 | 2020-08-19 | Avinger, Inc. | High speed chronic total occlusion crossing devices |
JP5813193B1 (ja) * | 2014-09-02 | 2015-11-17 | 株式会社モリタ製作所 | 医療用小型吸引装置 |
US10314667B2 (en) | 2015-03-25 | 2019-06-11 | Covidien Lp | Cleaning device for cleaning medical instrument |
US10568520B2 (en) | 2015-07-13 | 2020-02-25 | Avinger, Inc. | Micro-molded anamorphic reflector lens for image guided therapeutic/diagnostic catheters |
AT516604B1 (de) * | 2015-07-13 | 2016-07-15 | Ami Agency Medical Innovations Gmbh | Instrument zum Entfernen von Körpergewebe aus einem Fistelgang |
US10292721B2 (en) | 2015-07-20 | 2019-05-21 | Covidien Lp | Tissue-removing catheter including movable distal tip |
US10314664B2 (en) | 2015-10-07 | 2019-06-11 | Covidien Lp | Tissue-removing catheter and tissue-removing element with depth stop |
EP3407777B1 (en) | 2016-01-25 | 2020-12-30 | Avinger, Inc. | Oct imaging catheter with lag correction |
CN113855176A (zh) * | 2016-02-15 | 2021-12-31 | 泰尔茂株式会社 | 医疗器械 |
CN108882948A (zh) | 2016-04-01 | 2018-11-23 | 阿维格公司 | 具有锯齿状切割器的旋切术导管 |
US10456161B2 (en) | 2016-04-14 | 2019-10-29 | Covidien Lp | Tissue-removing catheter with adjustment mechanism |
US9962180B2 (en) | 2016-04-27 | 2018-05-08 | Covidien Lp | Catheter including drive assembly for rotating and reciprocating tissue-removing element |
WO2017210466A1 (en) | 2016-06-03 | 2017-12-07 | Avinger, Inc. | Catheter device with detachable distal end |
CN109414273B (zh) | 2016-06-30 | 2023-02-17 | 阿维格公司 | 具有可塑形的远侧头端的斑块切除导管 |
EP3634528B1 (en) | 2017-06-07 | 2023-06-07 | Shifamed Holdings, LLC | Intravascular fluid movement devices, systems, and methods of use |
CN111556763B (zh) | 2017-11-13 | 2023-09-01 | 施菲姆德控股有限责任公司 | 血管内流体运动装置、系统 |
JP7410034B2 (ja) | 2018-02-01 | 2024-01-09 | シファメド・ホールディングス・エルエルシー | 血管内血液ポンプならびに使用および製造の方法 |
WO2021016372A1 (en) | 2019-07-22 | 2021-01-28 | Shifamed Holdings, Llc | Intravascular blood pumps with struts and methods of use and manufacture |
EP4034192A4 (en) | 2019-09-25 | 2023-11-29 | Shifamed Holdings, LLC | INTRAVASCULAR BLOOD PUMP SYSTEMS AND METHODS OF USE AND CONTROL THEREOF |
EP4044942A4 (en) | 2019-10-18 | 2023-11-15 | Avinger, Inc. | CROSSING OCCLUSION DEVICES |
WO2023084305A1 (en) | 2021-11-12 | 2023-05-19 | Petrus Antonius Besselink | A multifunctional device for use in atherectomies and related endoluminal procedures |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0526042A1 (en) * | 1991-07-22 | 1993-02-03 | Theratek International, Inc. | Catheter with improved fluid infusion |
US5507795A (en) * | 1994-04-29 | 1996-04-16 | Devices For Vascular Intervention, Inc. | Catheter with perfusion system |
US5632754A (en) * | 1994-12-23 | 1997-05-27 | Devices For Vascular Intervention | Universal catheter with interchangeable work element |
US20090216180A1 (en) * | 2008-02-25 | 2009-08-27 | Fox Hollow Technologies, Inc. | Methods and devices for cutting tissue |
Family Cites Families (586)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1481078A (en) * | 1922-11-24 | 1924-01-15 | Albertson & Company | Flexible shafting |
US2178790A (en) * | 1938-05-07 | 1939-11-07 | Abner E Henry | Cutting implement |
US2701559A (en) * | 1951-08-02 | 1955-02-08 | William A Cooper | Apparatus for exfoliating and collecting diagnostic material from inner walls of hollow viscera |
US2850007A (en) * | 1956-05-31 | 1958-09-02 | American Cyanamid Co | Biopsy device |
US3064851A (en) | 1957-08-06 | 1962-11-20 | Canning Pekara Inc | Latch and hinge mechanism |
US3064651A (en) * | 1959-05-26 | 1962-11-20 | Henderson Edward | Hypodermic needle |
US3082805A (en) * | 1960-12-21 | 1963-03-26 | John H Royce | Tissue macerator |
US3320957A (en) * | 1964-05-21 | 1967-05-23 | Sokolik Edward | Surgical instrument |
GB1235321A (en) * | 1968-01-30 | 1971-06-09 | Nat Res Dev | Improvements in or relating to drills for clearing obstructions |
US3732858A (en) * | 1968-09-16 | 1973-05-15 | Surgical Design Corp | Apparatus for removing blood clots, cataracts and other objects from the eye |
ES152231Y (es) * | 1969-10-02 | 1970-07-01 | Ballestero Sierra | Un trocar perfeccionado. |
US3683891A (en) * | 1970-06-26 | 1972-08-15 | Marshall Eskridge | Tissue auger |
US3749085A (en) * | 1970-06-26 | 1973-07-31 | J Willson | Vascular tissue removing device |
US3945375A (en) * | 1972-04-04 | 1976-03-23 | Surgical Design Corporation | Rotatable surgical instrument |
SU442795A1 (ru) | 1972-04-27 | 1974-09-15 | Л.С. Юхин | Устройство дл внутрисосудистых операций |
US3815604A (en) * | 1972-06-19 | 1974-06-11 | Malley C O | Apparatus for intraocular surgery |
US3800783A (en) * | 1972-06-22 | 1974-04-02 | K Jamshidi | Muscle biopsy device |
US3831585A (en) * | 1972-07-19 | 1974-08-27 | T Brondy | Retrograde renal biopsy device |
US3837345A (en) * | 1973-08-31 | 1974-09-24 | A Matar | Venous valve snipper |
US3845375A (en) * | 1973-11-09 | 1974-10-29 | Mclaughlin Ward & Co | Electronic rotational sensor |
US3937222A (en) * | 1973-11-09 | 1976-02-10 | Surgical Design Corporation | Surgical instrument employing cutter means |
US3976077A (en) * | 1975-02-03 | 1976-08-24 | Kerfoot Jr Franklin W | Eye surgery device |
US4007732A (en) * | 1975-09-02 | 1977-02-15 | Robert Carl Kvavle | Method for location and removal of soft tissue in human biopsy operations |
US4038985A (en) * | 1975-10-07 | 1977-08-02 | Medico Developments, Inc. | Device for repairing arteries |
US3995619A (en) * | 1975-10-14 | 1976-12-07 | Glatzer Stephen G | Combination subcutaneous suture remover, biopsy sampler and syringe |
US4030503A (en) * | 1975-11-05 | 1977-06-21 | Clark Iii William T | Embolectomy catheter |
US4020847A (en) * | 1975-11-05 | 1977-05-03 | Clark Iii William T | Rotating cutter catheter |
US4034744A (en) * | 1975-11-13 | 1977-07-12 | Smith Kline Instruments, Inc. | Ultrasonic scanning system with video recorder |
US4177797A (en) * | 1977-03-04 | 1979-12-11 | Shelby M. Baylis | Rotary biopsy device and method of using same |
US4112708A (en) * | 1976-06-21 | 1978-09-12 | Nippon Cable Systems Inc. | Flexible drive cable |
SU665908A1 (ru) | 1977-11-09 | 1979-06-05 | Silin Semen A | Устройство дл внутрисосудистых операций |
US4210146A (en) * | 1978-06-01 | 1980-07-01 | Anton Banko | Surgical instrument with flexible blade |
US4306562A (en) * | 1978-12-01 | 1981-12-22 | Cook, Inc. | Tear apart cannula |
JPS5581633A (en) * | 1978-12-15 | 1980-06-19 | Olympus Optical Co | Endoscope |
US4273128A (en) * | 1980-01-14 | 1981-06-16 | Lary Banning G | Coronary cutting and dilating instrument |
US4306570A (en) * | 1980-08-20 | 1981-12-22 | Matthews Larry S | Counter rotating biopsy needle |
US4368730A (en) * | 1981-02-12 | 1983-01-18 | Nigel Sharrock | Intravenous catheter |
GB2093353B (en) | 1981-02-25 | 1984-09-19 | Dyonics Inc | A surgical instrument for arthroscopic arthroplasty |
US4436091A (en) * | 1981-03-20 | 1984-03-13 | Surgical Design Corporation | Surgical cutting instrument with release mechanism |
DE3126703A1 (de) | 1981-07-07 | 1983-01-27 | Dr. Karl Thomae Gmbh, 7950 Biberach | Bromhexin-retardform und verfahren zu ihrer herstellung |
JPS5887494U (ja) * | 1981-12-05 | 1983-06-14 | 株式会社モリタ製作所 | 医療用小型モ−タの速度制御装置 |
CH660015A5 (de) | 1982-02-01 | 1987-03-13 | Sandoz Ag | Polymerisat- und tensidhaltige praeparate, deren herstellung und verwendung. |
US4445509A (en) * | 1982-02-04 | 1984-05-01 | Auth David C | Method and apparatus for removal of enclosed abnormal deposits |
US4692141A (en) * | 1982-03-08 | 1987-09-08 | Mahurkar Sakharam D | Double lumen catheter |
US4512344A (en) * | 1982-05-12 | 1985-04-23 | Barber Forest C | Arthroscopic surgery dissecting apparatus |
US4424045A (en) * | 1982-05-24 | 1984-01-03 | Pennwalt Corporation | Rigid high speed flexible shaft casing assembly for tight radii installations |
DE3235612A1 (de) | 1982-09-25 | 1984-03-29 | Bayer Ag, 5090 Leverkusen | Mikroemulsionen |
US4490139A (en) * | 1983-01-28 | 1984-12-25 | Eli Lilly And Company | Implant needle and method |
US4936987A (en) * | 1983-03-07 | 1990-06-26 | Calgon Corporation | Synergistic scale and corrosion inhibiting admixtures containing carboxylic acid/sulfonic acid polymers |
US4603694A (en) * | 1983-03-08 | 1986-08-05 | Richards Medical Company | Arthroscopic shaver |
US4730616A (en) * | 1983-08-12 | 1988-03-15 | Advanced Cardiovascular Systems, Inc. | Multiple probe angioplasty apparatus and method |
US5669936A (en) | 1983-12-09 | 1997-09-23 | Endovascular Technologies, Inc. | Endovascular grafting system and method for use therewith |
US5104399A (en) | 1986-12-10 | 1992-04-14 | Endovascular Technologies, Inc. | Artificial graft and implantation method |
DE3347671A1 (de) * | 1983-12-31 | 1985-07-11 | Richard Wolf Gmbh, 7134 Knittlingen | Instrument zur entnahme von gewebeproben |
US4631052A (en) * | 1984-01-03 | 1986-12-23 | Intravascular Surgical Instruments, Inc. | Method and apparatus for surgically removing remote deposits |
US4589412A (en) * | 1984-01-03 | 1986-05-20 | Intravascular Surgical Instruments, Inc. | Method and apparatus for surgically removing remote deposits |
US5024651A (en) | 1984-05-14 | 1991-06-18 | Surgical Systems & Instruments, Inc. | Atherectomy system with a sleeve |
US4979939A (en) | 1984-05-14 | 1990-12-25 | Surgical Systems & Instruments, Inc. | Atherectomy system with a guide wire |
US4754755A (en) * | 1984-05-14 | 1988-07-05 | Husted Royce Hill | Catheter with a rotary blade |
US4732154A (en) * | 1984-05-14 | 1988-03-22 | Surgical Systems & Instruments, Inc. | Rotary catheter system |
US5007896A (en) | 1988-12-19 | 1991-04-16 | Surgical Systems & Instruments, Inc. | Rotary-catheter for atherectomy |
US4957482A (en) | 1988-12-19 | 1990-09-18 | Surgical Systems & Instruments, Inc. | Atherectomy device with a positive pump means |
US5135531A (en) | 1984-05-14 | 1992-08-04 | Surgical Systems & Instruments, Inc. | Guided atherectomy system |
US4819634A (en) * | 1984-05-14 | 1989-04-11 | Surgical Systems & Instruments | Rotary-catheter for atherectomy system |
US4842579B1 (en) * | 1984-05-14 | 1995-10-31 | Surgical Systems & Instr Inc | Atherectomy device |
US4894051A (en) * | 1984-05-14 | 1990-01-16 | Surgical Systems & Instruments, Inc. | Atherectomy system with a biasing sleeve and method of using the same |
US4883458A (en) * | 1987-02-24 | 1989-11-28 | Surgical Systems & Instruments, Inc. | Atherectomy system and method of using the same |
US4886490A (en) * | 1984-05-14 | 1989-12-12 | Surgical Systems & Instruments, Inc. | Atherectomy catheter system and method of using the same |
US5002553A (en) | 1984-05-14 | 1991-03-26 | Surgical Systems & Instruments, Inc. | Atherectomy system with a clutch |
US4979951A (en) | 1984-05-30 | 1990-12-25 | Simpson John B | Atherectomy device and method |
US4781186A (en) * | 1984-05-30 | 1988-11-01 | Devices For Vascular Intervention, Inc. | Atherectomy device having a flexible housing |
US4926858A (en) * | 1984-05-30 | 1990-05-22 | Devices For Vascular Intervention, Inc. | Atherectomy device for severe occlusions |
US4646719A (en) * | 1984-06-11 | 1987-03-03 | Aries Medical Incorporated | Intra-aortic balloon catheter having flexible torque transmitting tube |
USRE33258E (en) * | 1984-07-23 | 1990-07-10 | Surgical Dynamics Inc. | Irrigating, cutting and aspirating system for percutaneous surgery |
US4646736A (en) * | 1984-09-10 | 1987-03-03 | E. R. Squibb & Sons, Inc. | Transluminal thrombectomy apparatus |
US4705038A (en) * | 1985-01-23 | 1987-11-10 | Dyonics, Inc. | Surgical system for powered instruments |
US4649919A (en) * | 1985-01-23 | 1987-03-17 | Precision Surgical Instruments, Inc. | Surgical instrument |
US4653496A (en) * | 1985-02-01 | 1987-03-31 | Bundy Mark A | Transluminal lysing system |
US4745919A (en) * | 1985-02-01 | 1988-05-24 | Bundy Mark A | Transluminal lysing system |
US4747406A (en) * | 1985-02-13 | 1988-05-31 | Intravascular Surgical Instruments, Inc. | Shaft driven, flexible intravascular recanalization catheter |
US4686982A (en) * | 1985-06-19 | 1987-08-18 | John Nash | Spiral wire bearing for rotating wire drive catheter |
US4706671A (en) * | 1985-05-02 | 1987-11-17 | Weinrib Harry P | Catheter with coiled tip |
US5628781A (en) | 1985-06-06 | 1997-05-13 | Thomas Jefferson University | Implant materials, methods of treating the surface of implants with microvascular endothelial cells, and the treated implants themselves |
US4679558A (en) * | 1985-08-12 | 1987-07-14 | Intravascular Surgical Instruments, Inc. | Catheter based surgical methods and apparatus therefor |
US4664112A (en) * | 1985-08-12 | 1987-05-12 | Intravascular Surgical Instruments, Inc. | Catheter based surgical methods and apparatus therefor |
US4790812A (en) * | 1985-11-15 | 1988-12-13 | Hawkins Jr Irvin F | Apparatus and method for removing a target object from a body passsageway |
US4696298A (en) * | 1985-11-19 | 1987-09-29 | Storz Instrument Company | Vitrectomy cutting mechanism |
US4646738A (en) * | 1985-12-05 | 1987-03-03 | Concept, Inc. | Rotary surgical tool |
CA1293663C (en) | 1986-01-06 | 1991-12-31 | David Christopher Auth | Transluminal microdissection device |
AU607692B2 (en) | 1986-01-06 | 1991-03-14 | Boston Scientific Corporation Northwest Technology Center, Inc. | Transluminal microdissection device |
US4771774A (en) * | 1986-02-28 | 1988-09-20 | Devices For Vascular Intervention, Inc. | Motor drive unit |
US4669469A (en) * | 1986-02-28 | 1987-06-02 | Devices For Vascular Intervention | Single lumen atherectomy catheter device |
US5000185A (en) | 1986-02-28 | 1991-03-19 | Cardiovascular Imaging Systems, Inc. | Method for intravascular two-dimensional ultrasonography and recanalization |
US4794931A (en) * | 1986-02-28 | 1989-01-03 | Cardiovascular Imaging Systems, Inc. | Catheter apparatus, system and method for intravascular two-dimensional ultrasonography |
US4696667A (en) * | 1986-03-20 | 1987-09-29 | Helmut Masch | Intravascular catheter and method |
US4728319A (en) * | 1986-03-20 | 1988-03-01 | Helmut Masch | Intravascular catheter |
US5350395A (en) | 1986-04-15 | 1994-09-27 | Yock Paul G | Angioplasty apparatus facilitating rapid exchanges |
US4757819A (en) * | 1986-05-21 | 1988-07-19 | Olympus Optical Co., Ltd. | Ultrasonic endoscope |
US4729763A (en) * | 1986-06-06 | 1988-03-08 | Henrie Rodney A | Catheter for removing occlusive material |
US4765332A (en) * | 1986-07-14 | 1988-08-23 | Medinnovations, Inc. | Pullback atherectomy catheter system |
US4747821A (en) * | 1986-10-22 | 1988-05-31 | Intravascular Surgical Instruments, Inc. | Catheter with high speed moving working head |
SE455834B (sv) * | 1986-10-31 | 1988-08-15 | Medinvent Sa | Anordning for transluminal implantation av en i huvudsak rorformig, radiellt expanderbar protes |
US4733662A (en) | 1987-01-20 | 1988-03-29 | Minnesota Mining And Manufacturing Company | Tissue gripping and cutting assembly for surgical instrument |
FR2610525A1 (fr) | 1987-02-05 | 1988-08-12 | Salomon Sa | Ski de fond presentant une nervure longitudinale en saillie par rapport a sa face superieure |
US4733622A (en) * | 1987-02-24 | 1988-03-29 | Ssmc Inc. | Thread end holder for sewing machine with thread winding bobbin |
US4923462A (en) * | 1987-03-17 | 1990-05-08 | Cordis Corporation | Catheter system having a small diameter rotatable drive member |
US4846192A (en) | 1987-04-17 | 1989-07-11 | Eastman Kodak Company | Rearwardly acting surgical catheter |
US4784636A (en) * | 1987-04-30 | 1988-11-15 | Schneider-Shiley (U.S.A.) Inc. | Balloon atheroectomy catheter |
US4817613A (en) * | 1987-07-13 | 1989-04-04 | Devices For Vascular Intervention, Inc. | Guiding catheter |
US4954338A (en) | 1987-08-05 | 1990-09-04 | Rohm And Haas Company | Microbicidal microemulsion |
US4867157A (en) * | 1987-08-13 | 1989-09-19 | Baxter Travenol Laboratories, Inc. | Surgical cutting instrument |
US4819635A (en) * | 1987-09-18 | 1989-04-11 | Henry Shapiro | Tubular microsurgery cutting apparatus |
DE3732236C1 (de) | 1987-09-24 | 1988-12-15 | Rainer Dr Baumgart | Rekanalisationskatheter |
US4844064A (en) * | 1987-09-30 | 1989-07-04 | Baxter Travenol Laboratories, Inc. | Surgical cutting instrument with end and side openings |
US5154705A (en) | 1987-09-30 | 1992-10-13 | Lake Region Manufacturing Co., Inc. | Hollow lumen cable apparatus |
US5165421A (en) | 1987-09-30 | 1992-11-24 | Lake Region Manufacturing Co., Inc. | Hollow lumen cable apparatus |
US4857046A (en) * | 1987-10-21 | 1989-08-15 | Cordis Corporation | Drive catheter having helical pump drive shaft |
US5047040A (en) | 1987-11-05 | 1991-09-10 | Devices For Vascular Intervention, Inc. | Atherectomy device and method |
US4870953A (en) * | 1987-11-13 | 1989-10-03 | Donmicheal T Anthony | Intravascular ultrasonic catheter/probe and method for treating intravascular blockage |
US4887613A (en) * | 1987-11-23 | 1989-12-19 | Interventional Technologies Inc. | Cutter for atherectomy device |
NZ222930A (en) | 1987-12-15 | 1990-08-28 | Moffat Appliances Ltd | Gas infra-red burner in heat exchanger |
US4850957A (en) * | 1988-01-11 | 1989-07-25 | American Biomed, Inc. | Atherectomy catheter |
US5053044A (en) | 1988-01-11 | 1991-10-01 | Devices For Vascular Intervention, Inc. | Catheter and method for making intravascular incisions |
DE3801318A1 (de) | 1988-01-19 | 1989-07-27 | Stocksmeier Uwe | Medizinischer katheter mit schneidvorrichtung |
US4886061A (en) * | 1988-02-09 | 1989-12-12 | Medinnovations, Inc. | Expandable pullback atherectomy catheter system |
US4899757A (en) * | 1988-02-22 | 1990-02-13 | Intertherapy, Inc. | Ultrasound imaging probe with zero dead space |
DE58906466D1 (de) | 1988-03-04 | 1994-02-03 | Angiomed Ag | Verfahren und Vorrichtung zum Entfernen von Ablagerungen in Gefässen und Organen von Lebewesen. |
US4838268A (en) * | 1988-03-07 | 1989-06-13 | Scimed Life Systems, Inc. | Non-over-the wire balloon catheter |
US5183432A (en) | 1988-03-19 | 1993-02-02 | Nihonmatai Co., Ltd. | Floating body of sophisticated shape produced from a single sheet of film with a single sealing |
US5372138A (en) | 1988-03-21 | 1994-12-13 | Boston Scientific Corporation | Acousting imaging catheters and the like |
US5368035A (en) | 1988-03-21 | 1994-11-29 | Boston Scientific Corporation | Ultrasound imaging guidewire |
US4935017A (en) | 1988-04-29 | 1990-06-19 | C. R. Bard, Inc. | Variable shaped catheter system and method for catheterization |
US4950238A (en) * | 1988-07-07 | 1990-08-21 | Clarence E. Sikes | Hydro-rotary vascular catheter |
US4919133A (en) * | 1988-08-18 | 1990-04-24 | Chiang Tien Hon | Catheter apparatus employing shape memory alloy structures |
US5071425A (en) | 1988-09-12 | 1991-12-10 | Devices For Vascular Intervention, Inc. | Atherectomy catheter and method of forming the same |
GB8822149D0 (en) | 1988-09-21 | 1988-10-26 | Ciba Geigy Ag | Treatment of aqueous systems |
DE8813144U1 (zh) | 1988-10-19 | 1988-12-15 | Guenther, Rolf W., Prof. Dr., 5100 Aachen, De | |
GB8829182D0 (en) | 1988-12-14 | 1989-01-25 | Univ Birmingham | Surgical instrument |
DE8900059U1 (zh) | 1989-01-04 | 1989-05-24 | Schneider (Europe) Ag, Zuerich, Ch | |
AU4945490A (en) | 1989-01-06 | 1990-08-01 | Angioplasty Systems Inc. | Electrosurgical catheter for resolving atherosclerotic plaque |
US4966604A (en) | 1989-01-23 | 1990-10-30 | Interventional Technologies Inc. | Expandable atherectomy cutter with flexibly bowed blades |
US4986807A (en) | 1989-01-23 | 1991-01-22 | Interventional Technologies, Inc. | Atherectomy cutter with radially projecting blade |
US5077506A (en) | 1989-02-03 | 1991-12-31 | Dyonics, Inc. | Microprocessor controlled arthroscopic surgical system |
US5087265A (en) | 1989-02-17 | 1992-02-11 | American Biomed, Inc. | Distal atherectomy catheter |
US5431673A (en) | 1989-02-17 | 1995-07-11 | American Biomed, Inc. | Distal atherectomy catheter |
US4994067A (en) | 1989-02-17 | 1991-02-19 | American Biomed, Inc. | Distal atherectomy catheter |
US4928693A (en) * | 1989-03-13 | 1990-05-29 | Schneider (Usa), Inc. | Pressure monitor catheter |
US5078723A (en) | 1989-05-08 | 1992-01-07 | Medtronic, Inc. | Atherectomy device |
ATE134492T1 (de) | 1989-06-01 | 1996-03-15 | Schneider Europ Ag | Katheteranordnung mit einem führungsdraht sowie verfahren zur herstellung eines solchen führungsdrahtes |
US5029588A (en) | 1989-06-15 | 1991-07-09 | Cardiovascular Imaging Systems, Inc. | Laser catheter with imaging capability |
US5226910A (en) | 1989-07-05 | 1993-07-13 | Kabushiki Kaisha Topcon | Surgical cutter |
US5269793A (en) | 1989-07-20 | 1993-12-14 | Devices For Vascular Intervention, Inc. | Guide wire systems for intravascular catheters |
US5100426A (en) | 1989-07-26 | 1992-03-31 | Fts Engineering, Inc. | Catheter for performing an atherectomy procedure |
US5211651A (en) | 1989-08-18 | 1993-05-18 | Evi Corporation | Catheter atherotome |
US5115814A (en) | 1989-08-18 | 1992-05-26 | Intertherapy, Inc. | Intravascular ultrasonic imaging probe and methods of using same |
US5282484A (en) | 1989-08-18 | 1994-02-01 | Endovascular Instruments, Inc. | Method for performing a partial atherectomy |
US5226909A (en) | 1989-09-12 | 1993-07-13 | Devices For Vascular Intervention, Inc. | Atherectomy device having helical blade and blade guide |
US4997435A (en) | 1989-09-25 | 1991-03-05 | Methodist Hospital Of Indiana Inc. | Percutaneous catheter with encapsulating receptacle |
US5092839A (en) | 1989-09-29 | 1992-03-03 | Kipperman Robert M | Coronary thrombectomy |
US5116352A (en) | 1989-10-06 | 1992-05-26 | Angiomed Ag | Apparatus for removing deposits from vessels |
US5049124A (en) | 1989-10-14 | 1991-09-17 | Dow Corning Wright Corporation | Catheter drive apparatus having fluid delivery bearing |
US5024234A (en) | 1989-10-17 | 1991-06-18 | Cardiovascular Imaging Systems, Inc. | Ultrasonic imaging catheter with guidewire channel |
US5009659A (en) | 1989-10-30 | 1991-04-23 | Schneider (Usa) Inc. | Fiber tip atherectomy catheter |
ZA908425B (en) | 1989-11-03 | 1991-07-31 | Rohm & Haas | Synergistic microbicidal combinations |
US5505210A (en) | 1989-11-06 | 1996-04-09 | Mectra Labs, Inc. | Lavage with tissue cutting cannula |
US5019088A (en) | 1989-11-07 | 1991-05-28 | Interventional Technologies Inc. | Ovoid atherectomy cutter |
US5026384A (en) | 1989-11-07 | 1991-06-25 | Interventional Technologies, Inc. | Atherectomy systems and methods |
US5085662A (en) | 1989-11-13 | 1992-02-04 | Scimed Life Systems, Inc. | Atherectomy catheter and related components |
US5030201A (en) | 1989-11-24 | 1991-07-09 | Aubrey Palestrant | Expandable atherectomy catheter device |
US5011490A (en) | 1989-12-07 | 1991-04-30 | Medical Innovative Technologies R&D Limited Partnership | Endoluminal tissue excision catheter system and method |
US5178625A (en) | 1989-12-07 | 1993-01-12 | Evi Corporation | Catheter atherotome |
GB8928076D0 (en) | 1989-12-12 | 1990-02-14 | Owen Mumford Ltd | Improvements relating to blood sampling devices |
US5003918A (en) | 1989-12-28 | 1991-04-02 | Interventional Technologies, Inc. | Apparatus for manufacturing atherectomy torque tubes |
US5120323A (en) | 1990-01-12 | 1992-06-09 | Schneider (Usa) Inc. | Telescoping guide catheter system |
US5916210A (en) | 1990-01-26 | 1999-06-29 | Intraluminal Therapeutics, Inc. | Catheter for laser treatment of atherosclerotic plaque and other tissue abnormalities |
US5074841A (en) | 1990-01-30 | 1991-12-24 | Microcision, Inc. | Atherectomy device with helical cutter |
US5152744A (en) | 1990-02-07 | 1992-10-06 | Smith & Nephew Dyonics | Surgical instrument |
US5084010A (en) | 1990-02-20 | 1992-01-28 | Devices For Vascular Intervention, Inc. | System and method for catheter construction |
US5092873A (en) | 1990-02-28 | 1992-03-03 | Devices For Vascular Intervention, Inc. | Balloon configuration for atherectomy catheter |
US5222966A (en) | 1990-02-28 | 1993-06-29 | Devices For Vascular Intervention, Inc. | Balloon connection and inflation lumen for atherectomy catheter |
US5366463A (en) | 1990-05-02 | 1994-11-22 | Ryan William J | Atherectomy catheter for the removal of atherosclerosis from within blood vessels |
US5267955A (en) | 1990-05-10 | 1993-12-07 | Lake Region Manufacturing Company, Inc. | Atherectomy device |
US5395311A (en) | 1990-05-14 | 1995-03-07 | Andrews; Winston A. | Atherectomy catheter |
US5154724A (en) | 1990-05-14 | 1992-10-13 | Andrews Winston A | Atherectomy catheter |
US5095911A (en) | 1990-05-18 | 1992-03-17 | Cardiovascular Imaging Systems, Inc. | Guidewire with imaging capability |
US5558093A (en) | 1990-05-18 | 1996-09-24 | Cardiovascular Imaging Systems, Inc. | Guidewire with imaging capability |
US5100424A (en) | 1990-05-21 | 1992-03-31 | Cardiovascular Imaging Systems, Inc. | Intravascular catheter having combined imaging abrasion head |
US5674232A (en) | 1990-06-05 | 1997-10-07 | Halliburton; Alexander George | Catheter and method of use thereof |
US5181920A (en) * | 1990-06-08 | 1993-01-26 | Devices For Vascular Intervention, Inc. | Atherectomy device with angioplasty balloon and method |
US5360443A (en) | 1990-06-11 | 1994-11-01 | Barone Hector D | Aortic graft for repairing an abdominal aortic aneurysm |
US5527298A (en) | 1990-06-11 | 1996-06-18 | Schneider (Usa) Inc. | Tracking guidewire |
JPH06114070A (ja) | 1990-06-22 | 1994-04-26 | Vance Prod Inc | 外科用組織切除装置 |
US5064435A (en) | 1990-06-28 | 1991-11-12 | Schneider (Usa) Inc. | Self-expanding prosthesis having stable axial length |
US5520189A (en) | 1990-07-13 | 1996-05-28 | Coraje, Inc. | Intravascular ultrasound imaging guidewire |
CA2048120A1 (en) | 1990-08-06 | 1992-02-07 | William J. Drasler | Thrombectomy method and device |
US5078722A (en) | 1990-08-14 | 1992-01-07 | Cordis Corporation | Method and apparatus for removing deposits from a vessel |
US5100423A (en) | 1990-08-21 | 1992-03-31 | Medical Engineering & Development Institute, Inc. | Ablation catheter |
US5127902A (en) | 1990-09-05 | 1992-07-07 | Medical Innovative Technologies R&D Limited Partnership | Apparatus and method for precisely controlling the excision of obstructive tissue in a human blood vessel |
US5250065A (en) | 1990-09-11 | 1993-10-05 | Mectra Labs, Inc. | Disposable lavage tip assembly |
US5114399A (en) | 1990-10-01 | 1992-05-19 | Intramed Laboratories | Surgical device |
US5190528A (en) | 1990-10-19 | 1993-03-02 | Boston University | Percutaneous transseptal left atrial cannulation system |
US5242460A (en) | 1990-10-25 | 1993-09-07 | Devices For Vascular Intervention, Inc. | Atherectomy catheter having axially-disposed cutting edge |
US5527292A (en) | 1990-10-29 | 1996-06-18 | Scimed Life Systems, Inc. | Intravascular device for coronary heart treatment |
US5496267A (en) | 1990-11-08 | 1996-03-05 | Possis Medical, Inc. | Asymmetric water jet atherectomy |
DE4036570A1 (de) | 1990-11-16 | 1992-05-21 | Osypka Peter | Katheter zur verminderung oder beseitigung von verengungen in gefaessen |
JP2550778B2 (ja) | 1990-11-30 | 1996-11-06 | 富士写真光機株式会社 | 超音波検査装置 |
US5108500A (en) | 1990-12-10 | 1992-04-28 | Rohm And Haas Company | Stabilization of water insoluble 3-isothiazolones |
US5054492A (en) | 1990-12-17 | 1991-10-08 | Cardiovascular Imaging Systems, Inc. | Ultrasonic imaging catheter having rotational image correlation |
US5112345A (en) | 1990-12-17 | 1992-05-12 | Interventional Technologies | Atherectomy cutter with arcuate blades |
US5110822A (en) | 1991-01-03 | 1992-05-05 | Rohm And Haas Company | Synergistic combinations of 4,5-dichloro-2-n-octyl-3-isothiazolone or 2-methyl-3-isothiazolone with ferric dimethyl dithiocarbamate fungicide |
CA2075973A1 (en) | 1991-02-19 | 1992-08-20 | Robert E. Fischell | Apparatus and method for atherectomy |
US5445155A (en) | 1991-03-13 | 1995-08-29 | Scimed Life Systems Incorporated | Intravascular imaging apparatus and methods for use and manufacture |
US5295958A (en) | 1991-04-04 | 1994-03-22 | Shturman Cardiology Systems, Inc. | Method and apparatus for in vivo heart valve decalcification |
CA2065634C (en) | 1991-04-11 | 1997-06-03 | Alec A. Piplani | Endovascular graft having bifurcation and apparatus and method for deploying the same |
US6134003A (en) | 1991-04-29 | 2000-10-17 | Massachusetts Institute Of Technology | Method and apparatus for performing optical measurements using a fiber optic imaging guidewire, catheter or endoscope |
WO1992019930A1 (en) | 1991-04-29 | 1992-11-12 | Massachusetts Institute Of Technology | Method and apparatus for optical imaging and measurement |
US6501551B1 (en) | 1991-04-29 | 2002-12-31 | Massachusetts Institute Of Technology | Fiber optic imaging endoscope interferometer with at least one faraday rotator |
IT1249059B (it) | 1991-05-22 | 1995-02-11 | Rosa Antonio | Dissettore-scollatore ad ultrasuoni di placche aterosclerotiche |
US5395335A (en) | 1991-05-24 | 1995-03-07 | Jang; G. David | Universal mode vascular catheter system |
US5569275A (en) | 1991-06-11 | 1996-10-29 | Microvena Corporation | Mechanical thrombus maceration device |
US5284486A (en) | 1991-06-11 | 1994-02-08 | Microvena Corporation | Self-centering mechanical medical device |
US5263928A (en) | 1991-06-14 | 1993-11-23 | Baxter International Inc. | Catheter and endoscope assembly and method of use |
US5273526A (en) | 1991-06-21 | 1993-12-28 | Lake Region Manufacturing Company, Inc. | Vascular occulusion removal devices and method |
US5217474A (en) | 1991-07-15 | 1993-06-08 | Zacca Nadim M | Expandable tip atherectomy method and apparatus |
US5242461A (en) | 1991-07-22 | 1993-09-07 | Dow Corning Wright | Variable diameter rotating recanalization catheter and surgical method |
US5336167A (en) | 1991-07-22 | 1994-08-09 | Theratek International, Inc. | Controller for intravascular catheter system |
JPH0542162A (ja) | 1991-08-15 | 1993-02-23 | Nissho Corp | 塞栓切除カテ−テル |
JP3084830B2 (ja) | 1991-08-29 | 2000-09-04 | 株式会社ニッショー | 塞栓切除カテ−テル |
US5377682A (en) | 1991-09-05 | 1995-01-03 | Matsushita Electric Industrial Co., Ltd. | Ultrasonic probe for transmission and reception of ultrasonic wave and ultrasonic diagnostic apparatus including ultrasonic probe |
US5285795A (en) | 1991-09-12 | 1994-02-15 | Surgical Dynamics, Inc. | Percutaneous discectomy system having a bendable discectomy probe and a steerable cannula |
US5263959A (en) | 1991-10-21 | 1993-11-23 | Cathco, Inc. | Dottering auger catheter system and method |
US5423846A (en) | 1991-10-21 | 1995-06-13 | Cathco, Inc. | Dottering auger catheter system |
AU669338B2 (en) | 1991-10-25 | 1996-06-06 | Cook Incorporated | Expandable transluminal graft prosthesis for repair of aneurysm and method for implanting |
US5316023A (en) | 1992-01-08 | 1994-05-31 | Expandable Grafts Partnership | Method for bilateral intra-aortic bypass |
US5224945A (en) | 1992-01-13 | 1993-07-06 | Interventional Technologies, Inc. | Compressible/expandable atherectomy cutter |
US5224949A (en) | 1992-01-13 | 1993-07-06 | Interventional Technologies, Inc. | Camming device |
DE9290166U1 (de) | 1992-01-13 | 1994-10-13 | Schneider Usa Inc | Chirurgisches Schneidwerkzeug |
ES2116355T3 (es) | 1992-01-13 | 1998-07-16 | Schneider Usa Inc | Dispositivo de corte para cateter de aterectomia. |
US5192291A (en) | 1992-01-13 | 1993-03-09 | Interventional Technologies, Inc. | Rotationally expandable atherectomy cutter assembly |
US5250059A (en) | 1992-01-22 | 1993-10-05 | Devices For Vascular Intervention, Inc. | Atherectomy catheter having flexible nose cone |
US5318032A (en) | 1992-02-05 | 1994-06-07 | Devices For Vascular Intervention | Guiding catheter having soft tip |
US5295493A (en) | 1992-03-19 | 1994-03-22 | Interventional Technologies, Inc. | Anatomical guide wire |
US5350390A (en) | 1992-03-25 | 1994-09-27 | Arieh Sher | Device for removal of intraluminal occlusions |
US5176693A (en) | 1992-05-11 | 1993-01-05 | Interventional Technologies, Inc. | Balloon expandable atherectomy cutter |
US5222956A (en) | 1992-07-06 | 1993-06-29 | Altair Instruments, Inc. | Surgical drill collet mechanism and bur |
JPH0630943A (ja) * | 1992-07-10 | 1994-02-08 | Nissho Corp | 塞栓切除カテ−テル |
US5269759A (en) | 1992-07-28 | 1993-12-14 | Cordis Corporation | Magnetic guidewire coupling for vascular dilatation apparatus |
US5306294A (en) | 1992-08-05 | 1994-04-26 | Ultrasonic Sensing And Monitoring Systems, Inc. | Stent construction of rolled configuration |
US5707376A (en) | 1992-08-06 | 1998-01-13 | William Cook Europe A/S | Stent introducer and method of use |
US5224488A (en) | 1992-08-31 | 1993-07-06 | Neuffer Francis H | Biopsy needle with extendable cutting means |
US5383460A (en) | 1992-10-05 | 1995-01-24 | Cardiovascular Imaging Systems, Inc. | Method and apparatus for ultrasound imaging and atherectomy |
US5356418A (en) | 1992-10-28 | 1994-10-18 | Shturman Cardiology Systems, Inc. | Apparatus and method for rotational atherectomy |
US5312427A (en) | 1992-10-16 | 1994-05-17 | Shturman Cardiology Systems, Inc. | Device and method for directional rotational atherectomy |
US5360432A (en) | 1992-10-16 | 1994-11-01 | Shturman Cardiology Systems, Inc. | Abrasive drive shaft device for directional rotational atherectomy |
JP3186256B2 (ja) | 1992-10-21 | 2001-07-11 | セイコーエプソン株式会社 | Tab用フレキシブル回路基板の製造方法 |
US5531690A (en) | 1992-10-30 | 1996-07-02 | Cordis Corporation | Rapid exchange catheter |
US5336178A (en) | 1992-11-02 | 1994-08-09 | Localmed, Inc. | Intravascular catheter with infusion array |
US5643297A (en) | 1992-11-09 | 1997-07-01 | Endovascular Instruments, Inc. | Intra-artery obstruction clearing apparatus and methods |
US5571122A (en) | 1992-11-09 | 1996-11-05 | Endovascular Instruments, Inc. | Unitary removal of plaque |
US5501694A (en) | 1992-11-13 | 1996-03-26 | Scimed Life Systems, Inc. | Expandable intravascular occlusion material removal devices and methods of use |
US5792157A (en) | 1992-11-13 | 1998-08-11 | Scimed Life Systems, Inc. | Expandable intravascular occlusion material removal devices and methods of use |
US5540707A (en) | 1992-11-13 | 1996-07-30 | Scimed Life Systems, Inc. | Expandable intravascular occlusion material removal devices and methods of use |
US5372602A (en) | 1992-11-30 | 1994-12-13 | Device For Vascular Intervention, Inc. | Method of removing plaque using catheter cutter with torque control |
AU677808B2 (en) | 1992-12-01 | 1997-05-08 | Intella Interventional Systems, Inc. | Vibratory element for crossing stenoses |
US5584842A (en) | 1992-12-02 | 1996-12-17 | Intramed Laboratories, Inc. | Valvulotome and method of using |
US5318576A (en) | 1992-12-16 | 1994-06-07 | Plassche Jr Walter M | Endovascular surgery systems |
US5373849A (en) | 1993-01-19 | 1994-12-20 | Cardiovascular Imaging Systems, Inc. | Forward viewing imaging catheter |
US5620447A (en) | 1993-01-29 | 1997-04-15 | Smith & Nephew Dyonics Inc. | Surgical instrument |
CA2114330A1 (en) | 1993-01-29 | 1994-07-30 | Smith & Nephew Endoscopy, Inc. | Rotatable curved instrument |
DE9303531U1 (de) | 1993-03-11 | 1994-07-14 | Redha Falah | Medizinisches Instrument |
US5378234A (en) | 1993-03-15 | 1995-01-03 | Pilot Cardiovascular Systems, Inc. | Coil polymer composite |
CH685738A5 (fr) | 1993-03-25 | 1995-09-29 | Ferromec Sa | Instrument médical pour l'élimination de dépôts formés sur les parois intérieures des artères ou des veines. |
US5372601A (en) | 1993-03-30 | 1994-12-13 | Lary; Banning G. | Longitudinal reciprocating incisor |
US5322508A (en) | 1993-04-08 | 1994-06-21 | Cordis Corporation | Guidewire fluid delivery system and method of use |
US5318528A (en) | 1993-04-13 | 1994-06-07 | Advanced Surgical Inc. | Steerable surgical devices |
US5429136A (en) | 1993-04-21 | 1995-07-04 | Devices For Vascular Intervention, Inc. | Imaging atherectomy apparatus |
US5716410A (en) | 1993-04-30 | 1998-02-10 | Scimed Life Systems, Inc. | Temporary stent and method of use |
US5456667A (en) | 1993-05-20 | 1995-10-10 | Advanced Cardiovascular Systems, Inc. | Temporary stenting catheter with one-piece expandable segment |
WO1994027501A1 (en) | 1993-05-24 | 1994-12-08 | Boston Scientific Corporation | Medical acoustic imaging catheter and guidewire |
US5531685A (en) | 1993-06-11 | 1996-07-02 | Catheter Research, Inc. | Steerable variable stiffness device |
AU678263B2 (en) | 1993-07-03 | 1997-05-22 | Medical Miracles Company Limited | Angioplasty catheter with guidewire |
US5514115A (en) * | 1993-07-07 | 1996-05-07 | Device For Vascular Intervention, Inc. | Flexible housing for intracorporeal use |
US5527325A (en) | 1993-07-09 | 1996-06-18 | Device For Vascular Intervention, Inc. | Atherectomy catheter and method |
US5419774A (en) | 1993-07-13 | 1995-05-30 | Scimed Life Systems, Inc. | Thrombus extraction device |
US5458585A (en) | 1993-07-28 | 1995-10-17 | Cardiovascular Imaging Systems, Inc. | Tracking tip for a work element in a catheter system |
US5395313A (en) | 1993-08-13 | 1995-03-07 | Naves; Neil H. | Reciprocating arthroscopic shaver |
US5441510A (en) | 1993-09-01 | 1995-08-15 | Technology Development Center | Bi-axial cutter apparatus for catheter |
US5626516A (en) | 1993-09-17 | 1997-05-06 | Phillips Plastics Corporation | Pressure actuated door |
US5573008A (en) | 1993-10-29 | 1996-11-12 | Boston Scientific Corporation | Multiple biopsy sampling coring device |
US5444078A (en) | 1993-10-01 | 1995-08-22 | Rohm And Haas Company | Fully water-dilutable microemulsions |
US5456689A (en) | 1993-10-13 | 1995-10-10 | Arnold J. Kresch | Method and device for tissue resection |
DE4335931B4 (de) | 1993-10-21 | 2006-10-12 | Cerasiv Gmbh Innovatives Keramik-Engineering | Hüftgelenkpfanne |
WO1995013033A1 (en) | 1993-11-08 | 1995-05-18 | Lazarus Harrison M | Intraluminal vascular graft and method |
US5507760A (en) | 1993-11-09 | 1996-04-16 | Devices For Vascular Intervention, Inc. | Cutter device |
US5443497A (en) | 1993-11-22 | 1995-08-22 | The Johns Hopkins University | Percutaneous prosthetic by-pass graft and method of use |
US5427107A (en) | 1993-12-07 | 1995-06-27 | Devices For Vascular Intervention, Inc. | Optical encoder for catheter device |
AU1399995A (en) | 1993-12-09 | 1995-06-27 | Devices For Vascular Intervention, Inc. | Composite drive shaft |
US5503155A (en) | 1994-01-26 | 1996-04-02 | Cardiovascular Imaging Systems, Inc. | Drive cable having internal lead wires |
US5591127A (en) | 1994-01-28 | 1997-01-07 | Barwick, Jr.; Billie J. | Phacoemulsification method and apparatus |
US5507769A (en) | 1994-10-18 | 1996-04-16 | Stentco, Inc. | Method and apparatus for forming an endoluminal bifurcated graft |
US5413107A (en) | 1994-02-16 | 1995-05-09 | Tetrad Corporation | Ultrasonic probe having articulated structure and rotatable transducer head |
US5485840A (en) | 1994-03-15 | 1996-01-23 | Bauman; Robert P. | Method of precise guidance for directional atherectomy using ultrasound |
US5624457A (en) | 1994-04-07 | 1997-04-29 | Devices For Vascular Intervention | Directional atherectomy device with flexible housing |
US5569279A (en) | 1994-04-29 | 1996-10-29 | Rainin; Edgar A. | Surgical abrading device |
US5466382A (en) | 1994-05-03 | 1995-11-14 | Rohm And Haas Company | Synergistic microbicidal combinations containing 4,5-dichloro-2-n-octyl-3-isothiazolone and certain commercial biocides |
USRE38335E1 (en) | 1994-05-24 | 2003-11-25 | Endius Incorporated | Surgical instrument |
US5628761A (en) | 1994-07-08 | 1997-05-13 | Rizik; David G. | Guide wire passage creation device |
US5531700A (en) | 1994-07-29 | 1996-07-02 | Cardiovascular Imaging Systems, Inc. | Convertible tip catheters and sheaths |
US5575817A (en) | 1994-08-19 | 1996-11-19 | Martin; Eric C. | Aorto femoral bifurcation graft and method of implantation |
US5609605A (en) | 1994-08-25 | 1997-03-11 | Ethicon, Inc. | Combination arterial stent |
WO1996010366A1 (en) | 1994-10-03 | 1996-04-11 | Heart Technology, Inc. | Transluminal thrombectomy apparatus |
US5571130A (en) | 1994-10-04 | 1996-11-05 | Advanced Cardiovascular Systems, Inc. | Atherectomy and prostectomy system |
US5491524A (en) | 1994-10-05 | 1996-02-13 | Carl Zeiss, Inc. | Optical coherence tomography corneal mapping apparatus |
US5549601A (en) | 1994-10-11 | 1996-08-27 | Devices For Vascular Intervention, Inc. | Delivery of intracorporeal probes |
US5507761A (en) | 1994-10-11 | 1996-04-16 | Duer; Edward Y. | Embolic cutting catheter |
US5512044A (en) | 1994-10-11 | 1996-04-30 | Duer; Edward Y. | Embolic cutting catheter |
US6032673A (en) | 1994-10-13 | 2000-03-07 | Femrx, Inc. | Methods and devices for tissue removal |
AU3783295A (en) | 1994-11-16 | 1996-05-23 | Advanced Cardiovascular Systems Inc. | Shape memory locking mechanism for intravascular stent |
US5626562A (en) | 1994-11-28 | 1997-05-06 | Devices For Vascular Intervention | Drug delivery catheter |
DE4444166C2 (de) | 1994-12-12 | 1998-09-24 | Urotech Med Tech Gmbh | Flexible Messervorrichtung für chirurgische Zwecke |
US5643296A (en) | 1994-12-16 | 1997-07-01 | Devices For Vasclar Intervention | Intravascular catheter with guiding structure |
US5584843A (en) | 1994-12-20 | 1996-12-17 | Boston Scientific Corporation | Shaped wire multi-burr rotational ablation device |
US5836957A (en) | 1994-12-22 | 1998-11-17 | Devices For Vascular Intervention, Inc. | Large volume atherectomy device |
US6027450A (en) | 1994-12-30 | 2000-02-22 | Devices For Vascular Intervention | Treating a totally or near totally occluded lumen |
CA2157697C (en) | 1995-01-10 | 2007-03-13 | Banning Gray Lary | Vascular incisor/dilator |
US5700687A (en) | 1995-01-30 | 1997-12-23 | Bedminster Bioconversion Corporation | Odor control system |
US5683449A (en) | 1995-02-24 | 1997-11-04 | Marcade; Jean Paul | Modular bifurcated intraluminal grafts and methods for delivering and assembling same |
US5985397A (en) | 1995-03-20 | 1999-11-16 | Witt; Alvin E. | Coated synthetic resin board tiles |
WO1996029941A1 (de) | 1995-03-28 | 1996-10-03 | Straub Federnfabrik Ag | Katheter zum ablösen von abnormalen ablagerungen in menschlichen blutgefässen |
WO1996029942A1 (de) | 1995-03-28 | 1996-10-03 | Straub Federnfabrik Ag | Katheter zum ablösen von abnormalen ablagerungen in menschlichen blutgefässen |
US5728123A (en) | 1995-04-26 | 1998-03-17 | Lemelson; Jerome H. | Balloon actuated catheter |
US5556408A (en) | 1995-04-27 | 1996-09-17 | Interventional Technologies Inc. | Expandable and compressible atherectomy cutter |
US5554163A (en) | 1995-04-27 | 1996-09-10 | Shturman Cardiology Systems, Inc. | Atherectomy device |
US5938645A (en) | 1995-05-24 | 1999-08-17 | Boston Scientific Corporation Northwest Technology Center Inc. | Percutaneous aspiration catheter system |
US5827229A (en) | 1995-05-24 | 1998-10-27 | Boston Scientific Corporation Northwest Technology Center, Inc. | Percutaneous aspiration thrombectomy catheter system |
US5596990A (en) | 1995-06-06 | 1997-01-28 | Yock; Paul | Rotational correlation of intravascular ultrasound image with guide catheter position |
US5618293A (en) | 1995-06-06 | 1997-04-08 | Smith & Nephews Dyonics, Inc. | Surgical instrument |
JPH11507251A (ja) | 1995-06-07 | 1999-06-29 | カーディマ・インコーポレイテッド | 冠状静脈洞用のガイドカテーテル |
US5779673A (en) | 1995-06-26 | 1998-07-14 | Focal, Inc. | Devices and methods for application of intraluminal photopolymerized gels |
US5883458A (en) | 1995-07-31 | 1999-03-16 | Murata Manufacturing Co., Ltd. | Terminal for a piezoelectric device |
US5681336A (en) | 1995-09-07 | 1997-10-28 | Boston Scientific Corporation | Therapeutic device for treating vien graft lesions |
US6027460A (en) | 1995-09-14 | 2000-02-22 | Shturman Cardiology Systems, Inc. | Rotatable intravascular apparatus |
US5707383A (en) | 1995-10-05 | 1998-01-13 | Xomed Surgical Products, Inc. | Method of removing soft tissue in the middle ear |
US6375615B1 (en) | 1995-10-13 | 2002-04-23 | Transvascular, Inc. | Tissue penetrating catheters having integral imaging transducers and their methods of use |
US6283983B1 (en) | 1995-10-13 | 2001-09-04 | Transvascular, Inc. | Percutaneous in-situ coronary bypass method and apparatus |
IL151563A0 (en) | 1995-10-13 | 2003-04-10 | Transvascular Inc | A longitudinal compression apparatus for compressing tissue |
US6302875B1 (en) | 1996-10-11 | 2001-10-16 | Transvascular, Inc. | Catheters and related devices for forming passageways between blood vessels or other anatomical structures |
US5830222A (en) | 1995-10-13 | 1998-11-03 | Transvascular, Inc. | Device, system and method for intersititial transvascular intervention |
US6283951B1 (en) | 1996-10-11 | 2001-09-04 | Transvascular, Inc. | Systems and methods for delivering drugs to selected locations within the body |
US5766192A (en) | 1995-10-20 | 1998-06-16 | Zacca; Nadim M. | Atherectomy, angioplasty and stent method and apparatus |
US5843022A (en) | 1995-10-25 | 1998-12-01 | Scimied Life Systems, Inc. | Intravascular device utilizing fluid to extract occlusive material |
US5989281A (en) | 1995-11-07 | 1999-11-23 | Embol-X, Inc. | Cannula with associated filter and methods of use during cardiac surgery |
US5868685A (en) | 1995-11-14 | 1999-02-09 | Devices For Vascular Intervention | Articulated guidewire |
US5697944A (en) | 1995-11-15 | 1997-12-16 | Interventional Technologies Inc. | Universal dilator with expandable incisor |
US5827304A (en) | 1995-11-16 | 1998-10-27 | Applied Medical Resources Corporation | Intraluminal extraction catheter |
US5688234A (en) | 1996-01-26 | 1997-11-18 | Cardiometrics Inc. | Apparatus and method for the treatment of thrombotic occlusions in vessels |
US5695506A (en) | 1996-02-06 | 1997-12-09 | Devices For Vascular Intervention | Catheter device with a flexible housing |
US5733296A (en) | 1996-02-06 | 1998-03-31 | Devices For Vascular Intervention | Composite atherectomy cutter |
JPH09215753A (ja) | 1996-02-08 | 1997-08-19 | Schneider Usa Inc | チタン合金製自己拡張型ステント |
US5800389A (en) | 1996-02-09 | 1998-09-01 | Emx, Inc. | Biopsy device |
US5855583A (en) | 1996-02-20 | 1999-01-05 | Computer Motion, Inc. | Method and apparatus for performing minimally invasive cardiac procedures |
US5709698A (en) | 1996-02-26 | 1998-01-20 | Linvatec Corporation | Irrigating/aspirating shaver blade assembly |
US6036707A (en) | 1996-03-07 | 2000-03-14 | Devices For Vascular Intervention | Catheter device having a selectively flexible housing |
US5830224A (en) | 1996-03-15 | 1998-11-03 | Beth Israel Deaconess Medical Center | Catheter apparatus and methodology for generating a fistula on-demand between closely associated blood vessels at a pre-chosen anatomic site in-vivo |
US5807329A (en) | 1996-05-07 | 1998-09-15 | Gelman; Martin L. | Displaceable catheter device |
US6152909A (en) | 1996-05-20 | 2000-11-28 | Percusurge, Inc. | Aspiration system and method |
US20010049517A1 (en) | 1997-03-06 | 2001-12-06 | Gholam-Reza Zadno-Azizi | Method for containing and removing occlusions in the carotid arteries |
US5709701A (en) | 1996-05-30 | 1998-01-20 | Parodi; Juan C. | Apparatus for implanting a prothesis within a body passageway |
US5779643A (en) | 1996-11-26 | 1998-07-14 | Hewlett-Packard Company | Imaging guidewire with back and forth sweeping ultrasonic source |
JP3658862B2 (ja) | 1996-06-03 | 2005-06-08 | ヤマハ株式会社 | 楽器用ホルダー |
WO1997046164A1 (en) | 1996-06-07 | 1997-12-11 | Scieran Technologies, Inc. | An apparatus and method for performing ophthalmic procedures |
US5843161A (en) | 1996-06-26 | 1998-12-01 | Cordis Corporation | Endoprosthesis assembly for percutaneous deployment and method of deploying same |
US5819738A (en) | 1996-07-03 | 1998-10-13 | Symbiosis Corporation | Jaw assembly having progressively larger teeth and endoscopic biopsy forceps instrument incorporating same |
US5820592A (en) | 1996-07-16 | 1998-10-13 | Hammerslag; Gary R. | Angiographic and/or guide catheter |
US5662671A (en) | 1996-07-17 | 1997-09-02 | Embol-X, Inc. | Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries |
US5735816A (en) | 1996-07-23 | 1998-04-07 | Medtronic, Inc. | Spiral sheath retainer for autoperfusion dilatation catheter balloon |
US5972019A (en) | 1996-07-25 | 1999-10-26 | Target Therapeutics, Inc. | Mechanical clot treatment device |
US6080170A (en) | 1996-07-26 | 2000-06-27 | Kensey Nash Corporation | System and method of use for revascularizing stenotic bypass grafts and other occluded blood vessels |
US5779721A (en) | 1996-07-26 | 1998-07-14 | Kensey Nash Corporation | System and method of use for revascularizing stenotic bypass grafts and other blood vessels |
US5827201A (en) | 1996-07-26 | 1998-10-27 | Target Therapeutics, Inc. | Micro-braided guidewire |
US6830577B2 (en) | 1996-07-26 | 2004-12-14 | Kensey Nash Corporation | System and method of use for treating occluded vessels and diseased tissue |
US5676697A (en) | 1996-07-29 | 1997-10-14 | Cardiovascular Dynamics, Inc. | Two-piece, bifurcated intraluminal graft for repair of aneurysm |
US7603166B2 (en) | 1996-09-20 | 2009-10-13 | Board Of Regents University Of Texas System | Method and apparatus for detection of vulnerable atherosclerotic plaque |
US6682536B2 (en) | 2000-03-22 | 2004-01-27 | Advanced Stent Technologies, Inc. | Guidewire introducer sheath |
US5713913A (en) | 1996-11-12 | 1998-02-03 | Interventional Technologies Inc. | Device and method for transecting a coronary artery |
US6217595B1 (en) | 1996-11-18 | 2001-04-17 | Shturman Cardiology Systems, Inc. | Rotational atherectomy device |
EP1011460A4 (en) | 1996-12-02 | 2001-09-19 | Angiotrax Inc | APPARATUS AND METHODS SUITABLE FOR PERCUTANEOUS SURGERY |
US5931848A (en) | 1996-12-02 | 1999-08-03 | Angiotrax, Inc. | Methods for transluminally performing surgery |
JP4200459B2 (ja) | 1997-01-06 | 2008-12-24 | 二郎 北村 | 免震装置または免震構造 |
US5893857A (en) | 1997-01-21 | 1999-04-13 | Shturman Cardiology Systems, Inc. | Handle for atherectomy device |
US6129734A (en) | 1997-01-21 | 2000-10-10 | Shturman Cardiology Systems, Inc. | Rotational atherectomy device with radially expandable prime mover coupling |
DE19703779C2 (de) | 1997-02-01 | 2003-06-05 | Karlsruhe Forschzent | Verfahren und Vorrichtung zur Herstellung eines dispersen Gemisches |
US5882329A (en) | 1997-02-12 | 1999-03-16 | Prolifix Medical, Inc. | Apparatus and method for removing stenotic material from stents |
US5720735A (en) | 1997-02-12 | 1998-02-24 | Dorros; Gerald | Bifurcated endovascular catheter |
EP1007139A4 (en) | 1997-02-12 | 2000-06-14 | Prolifix Medical Inc | ENDOVASCULAR PROSTHESIS EXTRACTION APPARATUS |
US6120516A (en) | 1997-02-28 | 2000-09-19 | Lumend, Inc. | Method for treating vascular occlusion |
US5741270A (en) | 1997-02-28 | 1998-04-21 | Lumend, Inc. | Manual actuator for a catheter system for treating a vascular occlusion |
US5968064A (en) | 1997-02-28 | 1999-10-19 | Lumend, Inc. | Catheter system for treating a vascular occlusion |
US6010449A (en) | 1997-02-28 | 2000-01-04 | Lumend, Inc. | Intravascular catheter system for treating a vascular occlusion |
US6217549B1 (en) | 1997-02-28 | 2001-04-17 | Lumend, Inc. | Methods and apparatus for treating vascular occlusions |
US6849068B1 (en) | 1997-03-06 | 2005-02-01 | Medtronic Ave, Inc. | Aspiration catheter |
US5843103A (en) | 1997-03-06 | 1998-12-01 | Scimed Life Systems, Inc. | Shaped wire rotational atherectomy device |
US5824055A (en) | 1997-03-25 | 1998-10-20 | Endotex Interventional Systems, Inc. | Stent graft delivery system and methods of use |
US5772674A (en) | 1997-03-31 | 1998-06-30 | Nakhjavan; Fred K. | Catheter for removal of clots in blood vessels |
US5810867A (en) | 1997-04-28 | 1998-09-22 | Medtronic, Inc. | Dilatation catheter with varied stiffness |
US5911734A (en) | 1997-05-08 | 1999-06-15 | Embol-X, Inc. | Percutaneous catheter and guidewire having filter and medical device deployment capabilities |
US5922003A (en) | 1997-05-09 | 1999-07-13 | Xomed Surgical Products, Inc. | Angled rotary tissue cutting instrument and method of fabricating the same |
US5954745A (en) | 1997-05-16 | 1999-09-21 | Gertler; Jonathan | Catheter-filter set having a compliant seal |
US6013072A (en) | 1997-07-09 | 2000-01-11 | Intraluminal Therapeutics, Inc. | Systems and methods for steering a catheter through body tissue |
US6048349A (en) | 1997-07-09 | 2000-04-11 | Intraluminal Therapeutics, Inc. | Systems and methods for guiding a medical instrument through a body |
US6159442A (en) | 1997-08-05 | 2000-12-12 | Mfic Corporation | Use of multiple stream high pressure mixer/reactor |
GB9717580D0 (en) | 1997-08-19 | 1997-10-22 | Curry Paul | Device for opening blocked tubes |
US6050949A (en) | 1997-09-22 | 2000-04-18 | Scimed Life Systems, Inc. | Catheher system having connectable distal and proximal portions |
US6361545B1 (en) | 1997-09-26 | 2002-03-26 | Cardeon Corporation | Perfusion filter catheter |
US5951480A (en) | 1997-09-29 | 1999-09-14 | Boston Scientific Corporation | Ultrasound imaging guidewire with static central core and tip |
US6066149A (en) | 1997-09-30 | 2000-05-23 | Target Therapeutics, Inc. | Mechanical clot treatment device with distal filter |
US5951482A (en) | 1997-10-03 | 1999-09-14 | Intraluminal Therapeutics, Inc. | Assemblies and methods for advancing a guide wire through body tissue |
US6193676B1 (en) | 1997-10-03 | 2001-02-27 | Intraluminal Therapeutics, Inc. | Guide wire assembly |
US6156046A (en) | 1997-11-07 | 2000-12-05 | Prolifix Medical, Inc. | Methods and systems for treating obstructions in a body lumen |
US5947985A (en) | 1997-11-12 | 1999-09-07 | Imran; Mir A. | Apparatus and method for cleaning diseased vein grafts |
US6183432B1 (en) | 1997-11-13 | 2001-02-06 | Lumend, Inc. | Guidewire and catheter with rotating and reciprocating symmetrical or asymmetrical distal tip |
US5938671A (en) | 1997-11-14 | 1999-08-17 | Reflow, Inc. | Recanalization apparatus and devices for use therein and method |
US5935108A (en) | 1997-11-14 | 1999-08-10 | Reflow, Inc. | Recanalization apparatus and devices for use therein and method |
US6330884B1 (en) | 1997-11-14 | 2001-12-18 | Transvascular, Inc. | Deformable scaffolding multicellular stent |
DE29722136U1 (de) | 1997-12-15 | 1999-04-15 | Ischinger Thomas Prof Dr | Vaskulärer Thrombektomiekatheter zur Entfernung von endoluminalem Thrombus |
US6027514A (en) | 1997-12-17 | 2000-02-22 | Fox Hollow Technologies, Inc. | Apparatus and method for removing occluding material from body lumens |
US6217527B1 (en) | 1998-09-30 | 2001-04-17 | Lumend, Inc. | Methods and apparatus for crossing vascular occlusions |
US6231546B1 (en) | 1998-01-13 | 2001-05-15 | Lumend, Inc. | Methods and apparatus for crossing total occlusions in blood vessels |
US6081738A (en) | 1998-01-15 | 2000-06-27 | Lumend, Inc. | Method and apparatus for the guided bypass of coronary occlusions |
AU1927399A (en) | 1998-01-16 | 1999-08-02 | Lumend, Inc. | Catheter apparatus for treating arterial occlusions |
US5865748A (en) | 1998-01-16 | 1999-02-02 | Guidant Corporation | Guided directional coronary atherectomy distal linear encoder |
JP2002502626A (ja) | 1998-02-10 | 2002-01-29 | アーテミス・メディカル・インコーポレイテッド | 補足装置およびその使用方法 |
JP4157183B2 (ja) | 1998-02-17 | 2008-09-24 | オリンパス株式会社 | 内視鏡用処置具 |
US6159195A (en) | 1998-02-19 | 2000-12-12 | Percusurge, Inc. | Exchange catheter and method of use |
US6398798B2 (en) | 1998-02-28 | 2002-06-04 | Lumend, Inc. | Catheter system for treating a vascular occlusion |
US6454727B1 (en) | 1998-03-03 | 2002-09-24 | Senorx, Inc. | Tissue acquisition system and method of use |
US6019778A (en) | 1998-03-13 | 2000-02-01 | Cordis Corporation | Delivery apparatus for a self-expanding stent |
US6561998B1 (en) | 1998-04-07 | 2003-05-13 | Transvascular, Inc. | Transluminal devices, systems and methods for enlarging interstitial penetration tracts |
US6482217B1 (en) | 1998-04-10 | 2002-11-19 | Endicor Medical, Inc. | Neuro thrombectomy catheter |
US6001112A (en) | 1998-04-10 | 1999-12-14 | Endicor Medical, Inc. | Rotational atherectomy device |
US6666874B2 (en) | 1998-04-10 | 2003-12-23 | Endicor Medical, Inc. | Rotational atherectomy system with serrated cutting tip |
US6383195B1 (en) | 1998-04-13 | 2002-05-07 | Endoline, Inc. | Laparoscopic specimen removal apparatus |
US6036646A (en) | 1998-07-10 | 2000-03-14 | Guided Therapy Systems, Inc. | Method and apparatus for three dimensional ultrasound imaging |
US6106515A (en) | 1998-08-13 | 2000-08-22 | Intraluminal Therapeutics, Inc. | Expandable laser catheter |
US6241744B1 (en) | 1998-08-14 | 2001-06-05 | Fox Hollow Technologies, Inc. | Apparatus for deploying a guidewire across a complex lesion |
US6095990A (en) | 1998-08-31 | 2000-08-01 | Parodi; Juan Carlos | Guiding device and method for inserting and advancing catheters and guidewires into a vessel of a patient in endovascular treatments |
US6440147B1 (en) | 1998-09-03 | 2002-08-27 | Rubicor Medical, Inc. | Excisional biopsy devices and methods |
US6022362A (en) | 1998-09-03 | 2000-02-08 | Rubicor Medical, Inc. | Excisional biopsy devices and methods |
US6620180B1 (en) | 1998-09-09 | 2003-09-16 | Medtronic Xomed, Inc. | Powered laryngeal cutting blade |
US6428551B1 (en) | 1999-03-30 | 2002-08-06 | Stereotaxis, Inc. | Magnetically navigable and/or controllable device for removing material from body lumens and cavities |
AU6279299A (en) | 1998-10-02 | 2000-04-26 | Stereotaxis, Inc. | Magnetically navigable and/or controllable device for removing material from body lumens and cavities |
US6264611B1 (en) | 1998-11-25 | 2001-07-24 | Ball Semiconductor, Inc. | Monitor for interventional procedures |
US6228076B1 (en) | 1999-01-09 | 2001-05-08 | Intraluminal Therapeutics, Inc. | System and method for controlling tissue ablation |
US6165199A (en) | 1999-01-12 | 2000-12-26 | Coaxia, Inc. | Medical device for removing thromboembolic material from cerebral arteries and methods of use |
US6191862B1 (en) | 1999-01-20 | 2001-02-20 | Lightlab Imaging, Llc | Methods and apparatus for high speed longitudinal scanning in imaging systems |
US7524289B2 (en) | 1999-01-25 | 2009-04-28 | Lenker Jay A | Resolution optical and ultrasound devices for imaging and treatment of body lumens |
US6110121A (en) | 1999-01-25 | 2000-08-29 | Lenker; Jay Alan | Method and apparatus for obtaining improved resolution from intraluminal ultrasound |
US6592526B1 (en) | 1999-01-25 | 2003-07-15 | Jay Alan Lenker | Resolution ultrasound devices for imaging and treatment of body lumens |
US6113615A (en) | 1999-02-03 | 2000-09-05 | Scimed Life Systems, Inc. | Atherectomy burr including a bias wire |
US6475226B1 (en) | 1999-02-03 | 2002-11-05 | Scimed Life Systems, Inc. | Percutaneous bypass apparatus and method |
WO2000045691A2 (en) | 1999-02-04 | 2000-08-10 | Da Silva Branco Antonio Carlos | Kit for endovascular venous surgery |
US6196963B1 (en) | 1999-03-02 | 2001-03-06 | Medtronic Ave, Inc. | Brachytherapy device assembly and method of use |
DE19911777A1 (de) | 1999-03-17 | 2000-09-21 | Merck Patent Gmbh | Verfahren zur Herstellung von kosmetischen Formulierungen |
US6245012B1 (en) | 1999-03-19 | 2001-06-12 | Nmt Medical, Inc. | Free standing filter |
US6911026B1 (en) | 1999-07-12 | 2005-06-28 | Stereotaxis, Inc. | Magnetically guided atherectomy |
US6066153A (en) | 1999-03-31 | 2000-05-23 | Lev; Avigdor | Device and method for resecting body tissues |
US6277138B1 (en) | 1999-08-17 | 2001-08-21 | Scion Cardio-Vascular, Inc. | Filter for embolic material mounted on expandable frame |
US6319275B1 (en) | 1999-04-07 | 2001-11-20 | Medtronic Ave, Inc. | Endolumenal prosthesis delivery assembly and method of use |
DE19917148C2 (de) | 1999-04-16 | 2002-01-10 | Inst Mikrotechnik Mainz Gmbh | Verfahren und Mikrovermischer zur Herstellung einer Dispersion |
US7526481B1 (en) | 1999-04-19 | 2009-04-28 | Oracle International Corporation | Web servers with queryable dynamic caches |
US6790215B2 (en) | 1999-04-30 | 2004-09-14 | Edwards Lifesciences Corporation | Method of use for percutaneous material removal device and tip |
US6238405B1 (en) | 1999-04-30 | 2001-05-29 | Edwards Lifesciences Corp. | Percutaneous material removal device and method |
DE19925184A1 (de) | 1999-05-26 | 2000-11-30 | Schering Ag | Kontinuierliches Verfahren zur Herstellung von morphologisch einheitlichen Mikro- und Nanopartikeln mittels Mikromischer sowie nach diesem Verfahren hergestellte Partikel |
US6126649A (en) | 1999-06-10 | 2000-10-03 | Transvascular, Inc. | Steerable catheter with external guidewire as catheter tip deflector |
US20030150821A1 (en) * | 1999-07-16 | 2003-08-14 | Bates Mark C. | Emboli filtration system and methods of use |
US6179859B1 (en) | 1999-07-16 | 2001-01-30 | Baff Llc | Emboli filtration system and methods of use |
US6142987A (en) | 1999-08-03 | 2000-11-07 | Scimed Life Systems, Inc. | Guided filter with support wire and methods of use |
US6445939B1 (en) | 1999-08-09 | 2002-09-03 | Lightlab Imaging, Llc | Ultra-small optical probes, imaging optics, and methods for using same |
US6231549B1 (en) | 1999-08-17 | 2001-05-15 | Sherwood Services, Ag | Shim device for enteral feeding system |
US6299622B1 (en) | 1999-08-19 | 2001-10-09 | Fox Hollow Technologies, Inc. | Atherectomy catheter with aligned imager |
US7713279B2 (en) | 2000-12-20 | 2010-05-11 | Fox Hollow Technologies, Inc. | Method and devices for cutting tissue |
US7887556B2 (en) | 2000-12-20 | 2011-02-15 | Fox Hollow Technologies, Inc. | Debulking catheters and methods |
US6638233B2 (en) | 1999-08-19 | 2003-10-28 | Fox Hollow Technologies, Inc. | Apparatus and methods for material capture and removal |
US20030125757A1 (en) | 2000-12-20 | 2003-07-03 | Fox Hollow Technologies, Inc. | Debulking catheters and methods |
US7708749B2 (en) | 2000-12-20 | 2010-05-04 | Fox Hollow Technologies, Inc. | Debulking catheters and methods |
US20030120295A1 (en) | 2000-12-20 | 2003-06-26 | Fox Hollow Technologies, Inc. | Debulking catheters and methods |
US6447525B2 (en) | 1999-08-19 | 2002-09-10 | Fox Hollow Technologies, Inc. | Apparatus and methods for removing material from a body lumen |
US8328829B2 (en) | 1999-08-19 | 2012-12-11 | Covidien Lp | High capacity debulking catheter with razor edge cutting window |
WO2001015609A1 (en) | 1999-08-31 | 2001-03-08 | Fox Hollow Technologies | Atherectomy catheter with a rotating and telescoping cutter |
US6187025B1 (en) | 1999-09-09 | 2001-02-13 | Noble-Met, Ltd. | Vascular filter |
WO2001019444A1 (en) * | 1999-09-17 | 2001-03-22 | Bacchus Vascular Inc. | Mechanical pump for removal of fragmented matter and methods of manufacture and use |
US6533749B1 (en) | 1999-09-24 | 2003-03-18 | Medtronic Xomed, Inc. | Angled rotary tissue cutting instrument with flexible inner member |
AU1313301A (en) | 1999-10-26 | 2001-05-08 | Mark Wilson Ian Webster | A guidewire positioning device |
ATE291738T1 (de) | 1999-10-28 | 2005-04-15 | Agensys Inc | Diagnose und behandlung von krebs unter verwendung von sgp28-ähnlichen molekülen |
US6263236B1 (en) | 1999-11-29 | 2001-07-17 | Illumenex Corporation | Non-occlusive expandable catheter |
WO2001043809A1 (en) | 1999-12-16 | 2001-06-21 | Advanced Cardiovascular Systems, Inc. | Catheter assembly and method for positioning the same at a bifurcated vessel |
DE19961257C2 (de) | 1999-12-18 | 2002-12-19 | Inst Mikrotechnik Mainz Gmbh | Mikrovermischer |
US6394976B1 (en) | 2000-01-31 | 2002-05-28 | Intraluminal Therapeutics, Inc. | Catheter for controlling the advancement of a guide wire |
US6629953B1 (en) | 2000-02-18 | 2003-10-07 | Fox Hollow Technologies, Inc. | Methods and devices for removing material from a vascular site |
GB2357762B (en) | 2000-03-13 | 2002-01-30 | Lundbeck & Co As H | Crystalline base of citalopram |
US20010031981A1 (en) | 2000-03-31 | 2001-10-18 | Evans Michael A. | Method and device for locating guidewire and treating chronic total occlusions |
CA2403925C (en) | 2000-04-05 | 2008-09-16 | Stx Medical, Inc. | Intralumenal material removal systems and methods |
US7344546B2 (en) | 2000-04-05 | 2008-03-18 | Pathway Medical Technologies | Intralumenal material removal using a cutting device for differential cutting |
US6565588B1 (en) | 2000-04-05 | 2003-05-20 | Pathway Medical Technologies, Inc. | Intralumenal material removal using an expandable cutting device |
US6627784B2 (en) | 2000-05-17 | 2003-09-30 | Hydro Dynamics, Inc. | Highly efficient method of mixing dissimilar fluids using mechanically induced cavitation |
US6422736B1 (en) | 2000-06-21 | 2002-07-23 | Eastman Kodak Company | Scalable impeller apparatus for preparing silver halide grains |
US6532380B1 (en) | 2000-06-30 | 2003-03-11 | Cedars Sinai Medical Center | Image guidance for coronary stent deployment |
US6425870B1 (en) | 2000-07-11 | 2002-07-30 | Vermon | Method and apparatus for a motorized multi-plane transducer tip |
US6497711B1 (en) | 2000-08-16 | 2002-12-24 | Scimed Life Systems, Inc. | Therectomy device having a light weight drive shaft and an imaging device |
DE10041823C2 (de) | 2000-08-25 | 2002-12-19 | Inst Mikrotechnik Mainz Gmbh | Verfahren und statischer Mikrovermischer zum Mischen mindestens zweier Fluide |
US6656195B2 (en) | 2000-09-22 | 2003-12-02 | Medtronic Xomed, Inc. | Flexible inner tubular members and rotary tissue cutting instruments having flexible inner tubular members |
US20020058904A1 (en) | 2000-11-08 | 2002-05-16 | Robert Boock | Thrombus removal device |
US7004173B2 (en) | 2000-12-05 | 2006-02-28 | Lumend, Inc. | Catheter system for vascular re-entry from a sub-intimal space |
US20070049958A1 (en) | 2005-08-30 | 2007-03-01 | Arthrex, Inc. | Spiral cut curved blade |
ATE499054T1 (de) | 2000-12-20 | 2011-03-15 | Fox Hollow Technologies Inc | Verkleinerungskatheter |
US20040167554A1 (en) | 2000-12-20 | 2004-08-26 | Fox Hollow Technologies, Inc. | Methods and devices for reentering a true lumen from a subintimal space |
US7699790B2 (en) | 2000-12-20 | 2010-04-20 | Ev3, Inc. | Debulking catheters and methods |
EP1767159A1 (en) | 2000-12-20 | 2007-03-28 | Fox Hollow Technologies Inc. | Catheter for removing atheromatous or thrombotic occlusive material |
US7169165B2 (en) | 2001-01-16 | 2007-01-30 | Boston Scientific Scimed, Inc. | Rapid exchange sheath for deployment of medical devices and methods of use |
US6569177B1 (en) | 2001-01-19 | 2003-05-27 | Scimed Life Systems, Inc. | Ablation atherectomy burr |
US6428552B1 (en) | 2001-01-22 | 2002-08-06 | Lumend, Inc. | Method and apparatus for crossing intravascular occlusions |
WO2002083229A2 (en) | 2001-04-16 | 2002-10-24 | Medtronic Percusurge, Inc. | Aspiration catheters and method of use |
US20030023263A1 (en) | 2001-07-24 | 2003-01-30 | Incept Llc | Apparatus and methods for aspirating emboli |
US6623437B2 (en) | 2001-08-28 | 2003-09-23 | Rex Medical, L.P. | Tissue biopsy apparatus |
US20030199747A1 (en) | 2002-04-19 | 2003-10-23 | Michlitsch Kenneth J. | Methods and apparatus for the identification and stabilization of vulnerable plaque |
US6932502B2 (en) | 2002-05-01 | 2005-08-23 | Hewlett-Packard Development Company, L.P. | Mixing apparatus |
US7153315B2 (en) | 2002-06-11 | 2006-12-26 | Boston Scientific Scimed, Inc. | Catheter balloon with ultrasonic microscalpel blades |
EP1534152A1 (en) | 2002-07-13 | 2005-06-01 | Stryker Corporation | System and method for performing irrigated nose and throat surgery |
US20040210245A1 (en) | 2002-07-26 | 2004-10-21 | John Erickson | Bendable needle with removable stylet |
US20040049225A1 (en) | 2002-09-11 | 2004-03-11 | Denison Andy E. | Aspiration catheter |
US7734332B2 (en) | 2002-10-18 | 2010-06-08 | Ariomedica Ltd. | Atherectomy system with imaging guidewire |
JP2006514369A (ja) | 2003-02-21 | 2006-04-27 | センサーマチック・エレクトロニックス・コーポレーション | 統合電子商品監視(eas)および販売時点管理(pos)システムとその方法 |
US20040193034A1 (en) | 2003-03-28 | 2004-09-30 | Lawrence Wasicek | Combined long rail/short rail IVUS catheter |
US8246640B2 (en) | 2003-04-22 | 2012-08-21 | Tyco Healthcare Group Lp | Methods and devices for cutting tissue at a vascular location |
US20050004594A1 (en) | 2003-07-02 | 2005-01-06 | Jeffrey Nool | Devices and methods for aspirating from filters |
JP4026829B2 (ja) | 2003-07-24 | 2007-12-26 | ローム アンド ハース カンパニー | 殺微生物組成物 |
JP2005068125A (ja) | 2003-08-21 | 2005-03-17 | Rohm & Haas Co | 殺生物剤配合物の調製方法 |
US20050090849A1 (en) | 2003-10-22 | 2005-04-28 | Adams Kenneth M. | Angled tissue cutting instruments and method of fabricating angled tissue cutting instrument having flexible inner tubular members of tube and single wrap construction |
US7338495B2 (en) | 2003-10-22 | 2008-03-04 | Medtronic Xomed, Inc. | Angled tissue cutting instruments having flexible inner tubular members of tube and sleeve construction |
US7488322B2 (en) | 2004-02-11 | 2009-02-10 | Medtronic, Inc. | High speed surgical cutting instrument |
WO2005084562A2 (de) | 2004-03-04 | 2005-09-15 | Straub Medical Ag | Katheter zum ansaugen, fragmentieren und hinausfördern von entfernbarem material aus blutgefässen |
US7959634B2 (en) | 2004-03-29 | 2011-06-14 | Soteira Inc. | Orthopedic surgery access devices |
DE102004015639B4 (de) | 2004-03-31 | 2007-05-03 | Siemens Ag | Vorrichtung zum Durchführen einer "Cutting-Balloon"-Intervention mit IVUS-Überwachung |
US7479148B2 (en) | 2004-11-08 | 2009-01-20 | Crescendo Technologies, Llc | Ultrasonic shear with asymmetrical motion |
JP2008543511A (ja) | 2005-06-24 | 2008-12-04 | ヴォルケイノウ・コーポレーション | 脈管の画像作製方法 |
KR100668852B1 (ko) | 2005-06-30 | 2007-01-16 | 주식회사 하이닉스반도체 | 듀티비 보정 장치 |
DE102005045373A1 (de) | 2005-09-22 | 2007-04-05 | Siemens Ag | Kathetervorrichtung |
US20080051812A1 (en) | 2006-08-01 | 2008-02-28 | Baxano, Inc. | Multi-Wire Tissue Cutter |
DE102005059271B4 (de) | 2005-12-12 | 2019-02-21 | Siemens Healthcare Gmbh | Kathetervorrichtung |
DE102005059262B4 (de) | 2005-12-12 | 2008-02-07 | Siemens Ag | Kathetervorrichtung |
US7951161B2 (en) | 2006-05-09 | 2011-05-31 | Medrad, Inc. | Atherectomy system having a variably exposed cutter |
US20070276419A1 (en) | 2006-05-26 | 2007-11-29 | Fox Hollow Technologies, Inc. | Methods and devices for rotating an active element and an energy emitter on a catheter |
US8007506B2 (en) | 2006-06-30 | 2011-08-30 | Atheromed, Inc. | Atherectomy devices and methods |
US20080045986A1 (en) | 2006-06-30 | 2008-02-21 | Atheromed, Inc. | Atherectomy devices and methods |
US8361094B2 (en) | 2006-06-30 | 2013-01-29 | Atheromed, Inc. | Atherectomy devices and methods |
US20080004645A1 (en) | 2006-06-30 | 2008-01-03 | Atheromed, Inc. | Atherectomy devices and methods |
US8628549B2 (en) | 2006-06-30 | 2014-01-14 | Atheromed, Inc. | Atherectomy devices, systems, and methods |
US20090018566A1 (en) | 2006-06-30 | 2009-01-15 | Artheromed, Inc. | Atherectomy devices, systems, and methods |
JP4776032B2 (ja) | 2006-07-26 | 2011-09-21 | 古河スカイ株式会社 | 熱交換器 |
WO2008042987A2 (en) | 2006-10-04 | 2008-04-10 | Pathway Medical Technologies, Inc. | Interventional catheters |
US20080161840A1 (en) | 2006-12-29 | 2008-07-03 | Vascure Ltd. | Atherectomy methods and apparatus |
CA2675619C (en) | 2007-01-19 | 2016-08-16 | Sunnybrook Health Sciences Centre | Scanning mechanisms for imaging probe |
US20080208227A1 (en) | 2007-02-23 | 2008-08-28 | Terumo Cardiovascular Systems Corporation | Self-contained dissector/harvester device |
US8574253B2 (en) | 2007-04-06 | 2013-11-05 | Hologic, Inc. | Method, system and device for tissue removal |
US20080312673A1 (en) | 2007-06-05 | 2008-12-18 | Viswanathan Raju R | Method and apparatus for CTO crossing |
US8475478B2 (en) | 2007-07-05 | 2013-07-02 | Cardiovascular Systems, Inc. | Cleaning apparatus and method for high-speed rotational atherectomy devices |
US8236016B2 (en) | 2007-10-22 | 2012-08-07 | Atheromed, Inc. | Atherectomy devices and methods |
US8070762B2 (en) | 2007-10-22 | 2011-12-06 | Atheromed Inc. | Atherectomy devices and methods |
US20090138031A1 (en) | 2007-11-24 | 2009-05-28 | Tsukernik Vladimir B | Thrombectomy catheter with a helical cutter |
US20090163851A1 (en) * | 2007-12-19 | 2009-06-25 | Holloway Kenneth A | Occlusive material removal device having selectively variable stiffness |
EP2262423B1 (en) | 2008-03-06 | 2018-01-10 | Covidien LP | Image enhancement and application functionality for medical and other uses |
US8062316B2 (en) | 2008-04-23 | 2011-11-22 | Avinger, Inc. | Catheter system and method for boring through blocked vascular passages |
US20090275966A1 (en) | 2008-05-05 | 2009-11-05 | Miroslav Mitusina | Flexible inner members having flexible regions comprising a plurality of intertwined helical cuts |
US9186170B2 (en) | 2008-06-05 | 2015-11-17 | Cardiovascular Systems, Inc. | Bidirectional expandable head for rotational atherectomy device |
US20100030216A1 (en) | 2008-07-30 | 2010-02-04 | Arcenio Gregory B | Discectomy tool having counter-rotating nucleus disruptors |
JP5042162B2 (ja) | 2008-08-12 | 2012-10-03 | 株式会社日立ハイテクノロジーズ | 半導体加工方法 |
KR101645754B1 (ko) | 2008-10-13 | 2016-08-04 | 코비디엔 엘피 | 카테테르 샤프트를 조작하는 장치 및 방법 |
DE102009014489B4 (de) | 2009-03-23 | 2011-03-10 | Siemens Aktiengesellschaft | Katheter und medizinische Vorrichtung |
CN102625673B (zh) | 2009-04-29 | 2014-12-24 | 泰科保健集团有限合伙公司 | 用于切割和研磨组织的方法及装置 |
AU2010248909B2 (en) | 2009-05-14 | 2013-03-21 | Covidien Lp | Easily cleaned atherectomy catheters and methods of use |
EP2448502B1 (en) | 2009-07-01 | 2022-04-06 | Avinger, Inc. | Atherectomy catheter with laterally-displaceable tip |
US8142464B2 (en) | 2009-07-21 | 2012-03-27 | Miroslav Mitusina | Flexible inner member having a flexible region composed of longitudinally and rotationally offset partial circumferential cuts |
WO2011040250A1 (ja) | 2009-09-29 | 2011-04-07 | コニカミノルタホールディングス株式会社 | アクチュエータ、駆動装置、およびカメラモジュール |
AU2010326063B2 (en) | 2009-12-02 | 2013-07-04 | Covidien Lp | Methods and devices for cutting tissue |
JP5511107B2 (ja) | 2009-12-11 | 2014-06-04 | コヴィディエン リミテッド パートナーシップ | 改良された物質捕捉能率を有する物質除去デバイスおよび方法 |
JP6269460B2 (ja) | 2014-12-10 | 2018-01-31 | 京セラドキュメントソリューションズ株式会社 | 画像形成装置 |
-
2010
- 2010-12-09 JP JP2012543286A patent/JP5511107B2/ja active Active
- 2010-12-09 RU RU2012121843/14A patent/RU2520801C2/ru not_active IP Right Cessation
- 2010-12-09 AU AU2010328078A patent/AU2010328078B2/en not_active Ceased
- 2010-12-09 KR KR1020137032766A patent/KR20140006106A/ko not_active Application Discontinuation
- 2010-12-09 CA CA2783301A patent/CA2783301C/en not_active Expired - Fee Related
- 2010-12-09 EP EP10796232.6A patent/EP2509519B1/en active Active
- 2010-12-09 US US12/964,544 patent/US20110144673A1/en not_active Abandoned
- 2010-12-09 CN CN201080055972.0A patent/CN102695463B/zh active Active
- 2010-12-09 KR KR1020127017894A patent/KR101398384B1/ko active IP Right Grant
- 2010-12-09 IN IN4977DEN2012 patent/IN2012DN04977A/en unknown
- 2010-12-09 WO PCT/US2010/059740 patent/WO2011072149A1/en active Application Filing
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- 2012-09-18 US US13/622,073 patent/US9028512B2/en active Active
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2013
- 2013-12-04 JP JP2013250793A patent/JP5750492B2/ja active Active
-
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- 2015-04-13 US US14/684,972 patent/US9913659B2/en active Active
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- 2018-01-29 US US15/882,320 patent/US10751082B2/en active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0526042A1 (en) * | 1991-07-22 | 1993-02-03 | Theratek International, Inc. | Catheter with improved fluid infusion |
US5507795A (en) * | 1994-04-29 | 1996-04-16 | Devices For Vascular Intervention, Inc. | Catheter with perfusion system |
US5632754A (en) * | 1994-12-23 | 1997-05-27 | Devices For Vascular Intervention | Universal catheter with interchangeable work element |
US20090216180A1 (en) * | 2008-02-25 | 2009-08-27 | Fox Hollow Technologies, Inc. | Methods and devices for cutting tissue |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103239272A (zh) * | 2012-11-03 | 2013-08-14 | 周建大 | 负压清创机 |
CN104869924A (zh) * | 2012-11-08 | 2015-08-26 | 柯惠有限合伙公司 | 具有可旋转切削件的组织移除导管 |
CN104869923A (zh) * | 2012-11-08 | 2015-08-26 | 柯惠有限合伙公司 | 包括操作控制机构的组织移除导管 |
CN104869923B (zh) * | 2012-11-08 | 2017-06-27 | 柯惠有限合伙公司 | 包括操作控制机构的组织移除导管 |
CN109394308A (zh) * | 2013-08-23 | 2019-03-01 | 柯惠Lp公司 | 标本取出装置 |
CN109394308B (zh) * | 2013-08-23 | 2021-08-20 | 柯惠Lp公司 | 标本取出装置 |
Also Published As
Publication number | Publication date |
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JP5511107B2 (ja) | 2014-06-04 |
IN2012DN04977A (zh) | 2015-09-25 |
CA2783301C (en) | 2015-02-24 |
US9913659B2 (en) | 2018-03-13 |
CN102695463B (zh) | 2015-01-14 |
AU2010328078A1 (en) | 2012-06-14 |
US20130018397A1 (en) | 2013-01-17 |
JP2014042847A (ja) | 2014-03-13 |
JP5750492B2 (ja) | 2015-07-22 |
RU2520801C2 (ru) | 2014-06-27 |
US20150216555A1 (en) | 2015-08-06 |
EP2509519A1 (en) | 2012-10-17 |
US20110144673A1 (en) | 2011-06-16 |
KR20120102108A (ko) | 2012-09-17 |
AU2010328078B2 (en) | 2013-07-04 |
US9028512B2 (en) | 2015-05-12 |
KR101398384B1 (ko) | 2014-05-23 |
US10751082B2 (en) | 2020-08-25 |
CA2783301A1 (en) | 2011-06-16 |
EP2509519B1 (en) | 2019-08-07 |
KR20140006106A (ko) | 2014-01-15 |
JP2013513442A (ja) | 2013-04-22 |
RU2012121843A (ru) | 2014-01-20 |
US20180146980A1 (en) | 2018-05-31 |
WO2011072149A1 (en) | 2011-06-16 |
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