CN102695462B - 用于切割组织的方法和装置 - Google Patents
用于切割组织的方法和装置 Download PDFInfo
- Publication number
- CN102695462B CN102695462B CN201080054485.2A CN201080054485A CN102695462B CN 102695462 B CN102695462 B CN 102695462B CN 201080054485 A CN201080054485 A CN 201080054485A CN 102695462 B CN102695462 B CN 102695462B
- Authority
- CN
- China
- Prior art keywords
- cutting element
- cutting
- atherosis
- edge
- ablation catheter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
- A61B17/320783—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions through side-hole, e.g. sliding or rotating cutter inside catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
- A61B17/320758—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with a rotating cutting instrument, e.g. motor driven
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
- A61B17/320758—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with a rotating cutting instrument, e.g. motor driven
- A61B2017/320775—Morcellators, impeller or propeller like means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
- A61B17/320783—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions through side-hole, e.g. sliding or rotating cutter inside catheter
- A61B2017/320791—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions through side-hole, e.g. sliding or rotating cutter inside catheter with cutter extending outside the cutting window
Abstract
本发明提供了一种导管，所述导管包括切割元件（4B），所述切割元件具有一个或多个凸出元件（26B）。切割元件在远端处具有杯形表面，所述杯形表面除了凸出元件之外是光滑且连续的。凸出元件具有弯曲表面（30B），当所述弯曲表面旋转，所述弯曲表面适于重新引导所述切割下的材料颗粒，以使得产生朝向切割元件的旋转轴线、导管的轴线、或颗粒物收集室中的一个或多个引导切割下的颗粒的流体涡旋。在本发明的其它方面中，切割元件沿着大体平行于切割元件的旋转轴线的方向振动。
Description
本发明要求2009年12月2日提交的名为“用于切割组织的方法和装置”的美国临时专利申请No.61/265,863的优先权，其内容以引用的方式并入本文中。
技术领域
本发明涉及用于粥样硬化切除导管的切割元件以及使用旋转切割元件从血流腔切割材料的方法。
背景技术
导管被用于从身体上移除不想要的组织。粥样硬化切除导管被用于从血管移除材料，以便使血管通畅并且提高通过血管的血流量。
在从血管移除材料时发生的一个问题是材料可以是软的或者硬的，并且可以在切割过程中发生变化。因此，切割元件应当既能够切割硬组织又能够切割软组织。在使用旋转切割件时发生的另一个问题是材料颗粒趋于远离导管以及远离基于导管的颗粒收集结构沿着切向于切割件的方向发生位移。因此，也期望的是朝向导管并且尤其朝向基于导管的颗粒收集结构引导切割下的颗粒。
发明内容
本发明提供了一种粥样硬化切除导管，所述粥样硬化切除导管包括：主体，所述主体具有开口；能够旋转的轴，所述能够旋转的轴联接到所述主体；组织收集室，所述组织收集室联接到所述主体并且定位在切割元件的远侧处；切割元件，所述切割元件联接到所述能够旋转的轴，以用于使所述切割元件围绕旋转轴线旋转，所述切割元件具有杯形表面和切割刃，所述杯形表面构造成当所述杯形表面沿着远侧方向运动时沿着远侧方向重新引导由所述切割刃切割下的组织；以及凸出元件，所述凸出元件从所述切割元件的所述杯形表面向外延伸，所述凸出元件构造成朝向所述切割元件的所述旋转轴线、导管的纵向轴线、或者所述组织收集室中的一个或多个引导切割下的材料颗粒。
本发明提供了一种粥样硬化切除导管，所述粥样硬化切除导管包括：主体，所述主体具有开口；能够旋转的轴，所述能够旋转的轴联接到所述主体；组织收集室，所述组织收集室联接到所述主体并且定位于所述切割元件的远侧处；和切割元件，所述切割元件联接到所述能够旋转的轴，以用于使所述切割元件围绕旋转轴线旋转，所述切割元件具有切割刃，并且所述切割元件构造成沿着基本平行于所述切割元件的所述旋转轴线的方向振动。
本发明提供了一种从体腔中移除材料的方法，所述方法包括：提供粥样硬化切除导管，所述粥样硬化切除导管包括：具有开口的主体；联接到所述主体的能够旋转的轴；联接到所述主体并且定位在切割元件的远侧处的组织收集室；切割元件，所述切割元件联接到所述能够旋转的轴，以用于使所述切割元件围绕旋转轴线旋转，所述切割元件具有杯形表面和切割刃，所述杯形表面构造成当所述杯形表面沿着远侧方向运动时沿着所述远侧方向重新引导被所述切割刃切割下的组织；以及凸出元件，所述凸出元件从所述切割元件的所述杯形表面向外延伸，所述凸出元件构造成朝向所述切割元件的所述旋转轴线、导管的纵向轴线、或者所述组织收集室中的一个或多个引导切割下的材料颗粒；将所述导管放置在体腔中；以及使所述导管在所述体腔中运动，以便使所述切割元件与所述体腔中的所述材料相接触。
本发明提供了一种从体腔移除材料的方法，所述方法包括：提供粥样硬化切除导管，所述粥样硬化切除导管包括：具有开口的主体；联接到所述主体的能够旋转的轴；联接到所述主体并且定位到所述切割元件的远侧处的组织收集室；和切割元件，所述切割元件联接到所述能够旋转的轴，以用于使所述切割元件围绕旋转轴线旋转，所述切割元件具有切割刃，并且所述切割元件构造成沿着基本平行于所述切割元件的所述旋转轴线的方向振动；将所述导管放置在所述体腔中；以及使所述导管在所述体腔中运动，以便使所述切割元件与所述体腔中的所述材料相接触。在一个实施例中，使所述导管沿着远侧方向运动，以便使所述切割刃与所述体腔中的所述材料相接触。
从以下优选实施例的描述、附图以及权利要求中本发明的这些和其它方面将变得显而易见。在附图和以下描述中陈述了本发明的一个或多个实施例的细节。从描述和附图，以及从权利要求中本发明的其它特征、目的和优势将变得显而易见。
附图说明
图1示出了粥样硬化切除导管的远端的等距视图；
图2是图1的粥样硬化切除导管的一部分的等距剖视图，且切割元件处于储存位置中；
图3是图1的粥样硬化切除导管的一部分的等距剖视图，且切割元件处于工作位置中；
图4示出了切割元件的实施例的等距视图；
图5示出了切割元件的实施例的端视图；
图6是切割元件的实施例的等距剖视图；
图7示出了切割元件的另一个实施例的端视图，所述切割元件可以与图1所示的粥样硬化切除导管一起使用；
图8示出了图7中图解的切割元件的实施例的等距视图；
图8A示出了图8中图解的切割元件实施例的凸出元件中的一个的等距视图；
图9示出了切割元件的另一个实施例的端视图，所述切割元件可以与图1所示的粥样硬化切除导管一起使用；
图10示出了图9中图解的切割元件的实施例的等距视图；
图10A示出了图10中图解的切割元件实施例的凸出元件中的一个的等距视图；
图11示出了图8中图解的切割元件的实施例的变型的等距视图；
图11A示出了图11中图解的切割元件实施例的凸出元件中的一个的等距视图；
图12图解了粥样硬化切除导管的具有切割元件的部分的等距剖视图，所述切割元件在大体沿着切割元件的轴线的方向上振动；
图13图解了图12所示的导管的部件的等距视图。
具体实施方式
本发明提供了一种粥样硬化切除导管，所述粥样硬化切除导管包括：主体，所述主体具有开口；能够旋转的轴，所述能够旋转的轴联接到所述主体；组织收集室，所述组织收集室联接到所述主体并且定位在切割元件的远侧处；切割元件，所述切割元件联接到所述能够旋转的轴，以用于使所述切割元件围绕旋转轴线旋转，所述切割元件具有杯形表面和切割刃，所述杯形表面构造成当所述杯形表面沿着远侧方向运动时沿着远侧方向重新引导由所述切割刃切割下的组织；以及凸出元件，所述凸出元件从所述切割元件的所述杯形表面向外延伸，所述凸出元件构造成朝向所述切割元件的所述旋转轴线、导管的纵向轴线、或者所述组织收集室中的一个或多个引导切割下的材料颗粒。在实施例中，所述凸出元件构造成朝向所述切割元件的所述旋转轴线引导切割下的材料颗粒。在一个实施例中，所述切割刃位于所述切割元件的径向外边缘处。在实施例中，所述凸出元件包括弯曲凸出元件切割刃。在实施例中，所述凸出元件包括第一壁，所述第一壁从所述弯曲凸出元件切割刃延伸到所述杯形表面，所述第一壁朝向所述切割元件的旋转轴线引导切割下的材料颗粒。
在实施例中，所述第一壁从在所述切割元件的径向外边缘处与所述切割刃成相对切向的角度弯曲到更靠近所述切割元件的所述旋转轴线的相对径向的角度。在一个实施例中，所述凸出元件包括远侧壁，所述远侧壁从第一弯曲凸出元件切割刃延伸到第二边缘，所述远侧壁相对于所述切割元件的所述旋转轴线形成小于90度的角。在实施例中，所述第一弯曲凸出元件切割刃与所述第二边缘相比位于更远侧。在一个实施例中，所述第一弯曲凸出元件切割刃和所述切割元件的切割刃之间的最小径向距离小于所述第二边缘和所述切割元件的所述切割刃之间的最小径向距离。在一个实施例中，其中，所述第一壁和所述远侧壁之间的夹角是钝角。
在一个实施例中，所述凸出元件从所述切割刃向近侧凹陷一纵向距离。例如，所述凸出元件能够从所述切割刃向近侧凹陷0.0010至0.0050英寸（0.0025至0.0127cm）的纵向距离。在实施例中，所述凸出元件从所述切割刃凹陷0.0010至0.0050英寸（0.0025至0.0127cm）的径向距离。
在一个实施例中，所述凸出元件包括第一壁，所述第一壁从凸出元件切割刃延伸到杯形表面，所述第一壁朝向所述切割元件的所述旋转轴线引导切割下的材料颗粒，并且其中，所述第一壁与所述杯形表面形成锐角，以便形成底切。在实施例中，所述凸出元件包括远侧壁，所述远侧壁从所述第一凸出元件切割刃延伸到第二边缘，所述远侧壁相对于所述切割元件的所述旋转轴线形成小于90度的角。在一个实施例中，所述第一凸出元件切割刃与所述第二边缘相比位于更远侧。在实施例中，所述第一凸出元件切割刃和所述切割元件的切割刃之间的最小径向距离小于所述第二边缘和所述切割元件的所述切割刃之间的最小径向距离。在实施例中，具有前角的壁散置在所述第一壁和所述远侧壁的相交部之间。在一个实施例中，所述前角是负的。
在实施例中，当沿着所述切割元件的所述旋转轴线观察时，所述切割元件的所述杯形表面在至少300度的整个区域上是光滑且不间断的。在一个实施例中，当沿着所述切割元件的所述旋转轴线观察时，对于所述切割元件的表面面积的至少90%来说，所述切割元件的所述杯形表面是光滑且不间断的。在实施例中，当沿着所述切割元件的所述旋转轴线观察时，所述切割元件的所述杯形表面具有外半径，所述杯形表面从所述旋转轴线到距所述外半径的距离的至少一半处是连续且不间断的。在一个实施例中，所述粥样硬化切除导管还包括多个凸出元件，当沿着所述切割元件的所述旋转轴线观察时，所述多个凸出元件共同占据小于60度且小于表面面积的5%的区域，并且对于所述表面面积的至少90%来说，所述杯形表面是光滑且不间断的。在一个实施例中，粥样硬化切除导管包括多个凸出元件，所述多个凸出元件从所述杯形表面向外延伸，所述多个凸出元件是1、2、3、4、6或8个凸出元件。
在一个实施例中，所述切割元件能够相对于所述开口在储存位置和切割位置之间运动。在实施例中，所述切割元件通过抵靠凸轮表面滑动所述切割元件而在所述储存位置和所述切割位置之间运动。在实施例中，所述导管的相对于近侧部分的远侧部分通过抵靠所述凸轮表面滑动所述切割元件而偏斜。在实施例中，所述切割元件构造成沿着基本平行于所述切割元件的所述旋转轴线的方向振动。
本发明提供了一种粥样硬化切除导管，所述粥样硬化切除导管包括：主体，所述主体具有开口；能够旋转的轴，所述能够旋转的轴联接到所述主体；组织收集室，所述组织收集室联接到所述主体并且定位于所述切割元件的远侧处；和切割元件，所述切割元件联接到所述能够旋转的轴，以用于使所述切割元件围绕旋转轴线旋转，所述切割元件具有切割刃，并且所述切割元件构造成沿着基本平行于所述切割元件的所述旋转轴线的方向振动。在一个实施例中，所述粥样硬化切除导管包括具有一个或多个凹陷部的斜坡，所述切割元件包括在所述切割元件的凸轮表面上的一个或多个凸出部分，当所述凸出部分和所述凹陷部对准时，所述一个或多个凸出部分配合在所述一个或多个凹陷部中，并且当所述切割元件旋转时所述凸出部分离开和进入所述凹陷部，从而致使所述切割元件振动。在一个实施例中，所述粥样硬化切除导管包括具有一个或多个凸出部分的斜坡，所述切割元件包括在所述切割元件的凸轮表面上的一个或多个凹陷部，当所述凸出部分和所述凹陷部对准时，所述一个或多个凸出部分配合在所述一个或多个凹陷部中，并且当所述切割元件旋转时所述凸出部分离开和进入所述凹陷部，从而致使所述切割元件振动。在一个实施例中，所述粥样硬化切除导管包括具有一个或多个凸出部分的斜坡，所述切割元件包括在所述切割元件的凸轮表面上的一个或多个凸出部分，并且当所述切割元件旋转时，所述凸出部分致使所述切割元件振动。
在一个实施例中，所述切割元件具有杯形表面，所述杯形表面构造成当所述杯形表面沿着远侧方向运动时沿着所述远侧方向重新引导由所述切割刃切割下的组织。在实施例中，所述切割刃是所述切割元件的径向外边缘。在实施例中，所述导管包括凸出元件，所述凸出元件从所述切割元件的所述杯形表面向外延伸。在实施例中，所述切割刃是所述切割元件的径向外边缘，并且当沿着所述切割元件的旋转轴线观察时，所述凸出元件从所述切割刃向近侧凹陷。在一个实施例中，所述切割元件能够相对于所述开口在储存位置和切割位置之间运动。在一个实施例中，所述切割元件通过抵靠凸轮表面滑动所述切割元件而在所述储存位置和所述切割位置之间运动。在一个实施例中，所述导管的相对于近侧部分的远侧部分通过抵靠所述凸轮表面滑动所述切割元件而偏斜。
本发明提供了一种从体腔中移除材料的方法，所述方法包括：提供粥样硬化切除导管，所述粥样硬化切除导管包括：具有开口的主体；联接到所述主体的能够旋转的轴；联接到所述主体并且定位在切割元件的远侧处的组织收集室；切割元件，所述切割元件联接到所述能够旋转的轴，以用于使所述切割元件围绕旋转轴线旋转，所述切割元件具有杯形表面和切割刃，所述杯形表面构造成当所述杯形表面沿着远侧方向运动时沿着所述远侧方向重新引导被所述切割刃切割下的组织；以及凸出元件，所述凸出元件从所述切割元件的所述杯形表面向外延伸，所述凸出元件构造成朝向所述切割元件的所述旋转轴线、导管的纵向轴线、或者所述组织收集室中的一个或多个引导切割下的材料颗粒；将所述导管放置在体腔中；以及使所述导管在所述体腔中运动，以便使所述切割元件与所述体腔中的所述材料相接触。在一个实施例中，所述导管沿着远侧方向运动，以便使所述切割刃与所述体腔中的所述材料相接触。在一个实施例中，所述导管放置在所述体腔中且所述切割元件位于储存位置中，并且使所述导管运动，以便使所述材料与处于切割位置中的所述切割元件相接触。在一个实施例中，体腔是血管。
本发明提供了一种从体腔移除材料的方法，所述方法包括：提供粥样硬化切除导管，所述粥样硬化切除导管包括：具有开口的主体；联接到所述主体的能够旋转的轴；联接到所述主体并且定位到所述切割元件的远侧处的组织收集室；和切割元件，所述切割元件联接到所述能够旋转的轴，以用于使所述切割元件围绕旋转轴线旋转，所述切割元件具有切割刃，并且所述切割元件构造成沿着基本平行于所述切割元件的所述旋转轴线的方向振动；将所述导管放置在所述体腔中；以及使所述导管在所述体腔中运动，以便使所述切割元件与所述体腔中的所述材料相接触。在一个实施例中，使所述导管沿着远侧方向运动，以便使所述切割刃与所述体腔中的所述材料相接触。在实施例中，将所述导管放置在所述体腔中且所述切割元件处于储存位置中，并且使所述导管运动，以便使所述材料与处于切割位置中的所述切割元件相接触。在实施例中，所述体腔是血管。
本发明提供了一种粥样硬化切除导管，所述粥样硬化切除导管具有能够既切除软组织也能够切除硬组织的切割元件。切割元件具有环绕杯形表面的锋利的切割刃。杯形表面将已切割的材料引导到组织室中。周向切割刃和杯形表面一起也适于切割并且移除相对较软的组织。
在本发明的一个方面中，提供了一种粥样硬化切除导管，所述粥样硬化切除导管具有从杯形表面延伸的一个或多个凸出元件。凸出元件可以从外切割刃纵向地和径向地凹陷诸如0.0010-0.0020英寸（0.0025至0.0051cm）的受控距离，但是在另一个实施例中，取决于应用，所述凸出元件可以更加靠近或更加远离外切割刃。凸出元件有助于打碎诸如钙化斑的硬组织。凸出元件略微从远端凹陷，以便使切割刃保持露出，以切割软组织。当切割元件遭遇太硬无法用切割刃充分切割的组织时，凸出元件施加更钝的力来帮助破坏较硬的组织。
在本发明的另一个方面中，凸出元件略微较小，以便杯形表面的相对较大的部分光滑并且不间断。这样，凸出元件不会过度妨碍切割元件利用杯形表面将组织引导到组织室中的能力。例如，当沿着纵向轴线观察时，凸出元件可以占据小于60度的区域。换言之，当沿着纵向轴线观察时，切割元件的杯形表面在至少300度的整个区域上是光滑且不间断的。换言之，当沿着纵向轴线观察时，对于切割元件的表面面积的至少95%来说，杯形表面可以是光滑且不间断的。
在本发明的又一个方面中，凸出元件具有的表面趋于朝向切割件的旋转轴线、导管轴线、或颗粒收集室中的一个或多个引导切割下的材料颗粒。
在本发明的再一个方面中，切割件沿着大体平行于所述切割件的轴线的方向振动，以便将力施加在切割下的材料颗粒上，这将沿着远侧方向朝向收集室引导所述切割下的材料颗粒或者双向引导所述切割下的材料颗粒。
参照图1至图4，示出了粥样硬化切除导管2，所述粥样硬化切除导管2具有用于从血流腔切割材料的切割元件4。切割元件4能够相对于导管2的主体8中的开口6在储存位置（图2）和切割位置（图3）之间运动。切割元件4相对于开口6向外运动，使得元件4的一部分从主体8向外延伸通过开口6。切割元件4可以相对于主体8和开口6定位，使得切割元件4小于90度露出以切割组织。当然，在不背离本发明的多个方面的前提下，可以露出切割元件4的更多部分。
取决于预期使用导管的解剖位置的要求，导管2可以具有3、4、5、6、7、8、9、10或12French（1、1.3、1.7、2、2.3、2.7、3、3.3、或4mm）的最大尺寸以及可以具有在20、30、40、60、80、100、120、150、180或210cm的范围内变化的工作长度。切割件4的直径优选地略小于最大尺寸的导管2的直径，典型地小于0.010″（0.025cm）、0.015″（0.038cm）、0.020″（0.051cm）、0.025″（0.064cm）或0.030″（0.076cm）。然而，这些相对的尺寸并不意味着是限制。
导管2向远侧运动通过血管，其中切割元件4处于如以下进一步详细描述的工作或切割位置中。当导管2运动通过血管时，组织由切割元件4切割并被引导到定位于切割元件4的远侧处的组织室12中。组织室12可以是略微细长的，以便容纳已切割的组织。
切割元件4从储存位置向近侧运动，以便切割元件4上的凸轮表面14接合导管2的主体8上的斜坡16。凸轮表面14和斜坡16之间的相互作用致使切割元件4运动到切割位置，并且也致使尖端18发生偏斜，这趋于使切割元件4朝向待切割的组织运动。
切割元件4联接到轴20，所述轴20延伸通过导管2中的管腔21。当轴旋转时，切割元件4围绕纵向轴线LA旋转。切割元件4以大约1至160,000转/分旋转，但是取决于具体应用，也可以以任何适当的速度旋转。
参照图2、4和5，示出了切割元件4。本文所使用的术语“沿着纵向轴线”将指的是图5的视图，所述视图示出了当沿着纵向轴线和/或旋转轴线的方向观察时切割元件4的远端。切割元件4具有切割刃22，所述切割刃22可以是连续无间断的圆形边缘，尽管在不背离本发明的范围的前提下，所述切割刃22也可以包括脊、齿、锯齿或其它特征。当切割元件4处于切割位置时，切割刃22可以位于切割元件4的径向外边缘23处。
切割元件4具有杯形表面24，所述杯形表面24将由切割刃22切割下的组织引导到组织室12中。杯形表面24可以是光滑且连续的表面，没有从纵向轴线LA到距切割刃22的外半径的距离的至少一半处中断表面24的光滑特性的通孔、齿、翅片或其它特征。杯形表面24也可以在相对于纵向轴线LA的至少300度的整个区域中没有任何这种特征。
切割件4可以由钢、碳化钨、碳化钨钴、碳化钨钼、碳化硅、氮化硅、陶瓷、非晶态金属或其它材料构成，以及可以通过包括车削、磨削、烧结、放电加工（EDM）、激光切割、热处理、沉淀硬化、铸造的方法或其它方法制造而成。
参照图4至图6，一个或多个凸出元件26从杯形表面24向外延伸，其中图5示出了两个凸出元件26。突出元件26是从杯形表面24突然相对凸起的小楔形材料。凸出元件26具有第一壁30和第二壁32，所述第一壁30和所述第二壁32皆径向延伸并且在所述第一壁30和所述第二壁32之间形成大约20度的角，使得两个凸出元件26一起占据大约40度的区域并且总共可以小于60度。第三壁34在第一壁30和第二壁32的径向内部分之间延伸。凸出元件26通过将相对较钝的力施加到硬组织或斑块上而有助于打碎硬组织和斑块，这是因为利用切割刃22切割这种组织通常并不有效。
凸出元件26总共占据杯形表面24的相对较小的部分。凸出元件26可以共同占据切割元件4的小于5%的表面区域。在本文中使用的术语“切割元件的表面区域”应当指的是从外部或切割刃22径向向内并且当沿着纵向轴线LA观察时露出的表面区域。换言之，当沿着纵向轴线观察时，切割元件的表面区域的至少95%是光滑的杯形表面。通过以此种方式设定凸出元件26的尺寸和定位，凸出元件26不会干扰切割元件4切割组织并且将所述组织重新引导到组织室中的能力，同时仍然利用凸出元件26提供打碎硬组织和斑块的能力。
凸出元件26可以从切割刃22纵向和/或径向地凹陷。凸出元件26可以从切割刃纵向（沿着轴线LA）凹陷0.0010至0.0020英寸（0.0025至0.0051cm）以及可以凹陷大约0.0015英寸（0.0038cm）。凸出元件26可以从切割刃22径向地凹陷大约相同的量。切割元件4的远侧壁38形成平坦表面40，所述平坦表面40垂直于纵向轴线LA，以便整个表面从切割刃凹陷相同的距离。远侧壁38可以呈现任何其它形状，诸如本文所述的弯曲形状或可以是有倾度、有斜度或有坡度的形状。
参照图7、8和8A，示出了另一个切割元件4A，其中，相同或相似的附图标记指代相同或相似的结构，并且除非另有说明，关于切割元件4的相同或相似特征的所有讨论均同样可应用于此。切割元件4A具有切割刃22A，所述切割刃22A可以是连续不间断的圆形边缘，尽管在不背离本发明的范围的前提下，所述切割刃22A也可以包括脊、齿、锯齿或其它特征。当切割元件4A位于切割位置时，切割刃22A可以位于切割元件4A的径向外边缘23A处。切割元件4A具有杯形表面24A，所述杯形表面24A将由切割刃22A切割下的组织引导到组织室12中（见图2）。杯形表面24A可以是如上关于切割元件4所述的基本光滑并且连续的表面。
一个或多个凸出元件26A从杯形表面24A向外延伸。图8示出了四个凸出元件26A，但是可以包括诸如1、2、3、4、6或8个的任何数量的凸出元件。凸出元件26A是从杯形表面24A突然相对凸起的小楔形材料。凸出元件26A具有第一壁30A和第二壁32A，所述第一壁30A和所述第二壁32A在一个实施例中皆径向延伸并且在所述第一壁30A和所述第二壁32A之间形成大约1至30度的角，使得四个凸出元件26A共同占据大约4至60度的区域并且总共可以小于60度。第三壁34A在第一壁30A和第二壁32A的径向内部分之间延伸。在一些实施例中，凸出元件26A可以占据杯形表面24A的相对较小的部分，并且按照如上关于切割元件4所述的方式，所述凸出元件26A可以从切割刃22A凹陷。在其它实施例中，切割元件的表面区域的至少60%、70%、80%或90%是光滑的杯形表面。
切割元件4A的远侧壁38A具有表面40A，所述表面40A相对于纵向轴线LA形成大约30至90度的角。整个表面40A仍可略微靠近切割刃22A但是从切割刃22A凹陷，使得整个表面40A距切割刃至少0.0010、0.0020、0.0030、0.0040或0.0050英寸（0.0025、0.0051、0.0076、0.0101、或0.0127cm）。与形成在壁32A和远侧壁38A的相交部处的边缘52相比，形成在壁30A和远侧壁38A的相交部处的边缘50更靠近切割刃22A。切割元件4A可以沿着任意方向旋转，使得凸出边缘50可以是前边缘或后边缘。在一些实施例中，凸出边缘可以距切割刃0.0010至0.0020英寸（0.0025至0.0051cm）。凸出元件26A可以全部以相同的方式形成或者彼此不同。例如，元件26A中的一些能够沿着不同的方向成角度，使得元件中的两个具有作为前边缘的凸出边缘50以及元件26A中的两个具有作为后边缘的凸出边缘50。在不背离本发明的各方面的前提下，凸出元件26A也可以对着不同的角度，具有不同高度或可以具有不同的径向长度。
参照图9、10和10A，示出了另一个切割元件4B，其中，相同或相似的附图标记指代相同或相似的结构，并且除非另有说明，关于切割元件4的相同或相似的特征的所有讨论同样可应用于此。切割元件4B具有切割刃22B，所述切割刃22B可以是连续不间断的圆形边缘，尽管在不背离本发明的范围的前提下，所述切割刃22B也可以包括脊、齿、锯齿或其它特征。当切割元件4B位于切割位置时，切割刃22B可以位于切割元件4B的径向外边缘23B处。切割元件4B具有杯形表面24B，所述杯形表面24B将由切割刃22B切割下的组织引导到组织室12中（见图2）。在一个实施例中，杯形表面24B可以是如以上关于切割元件4所述的基本光滑且连续的表面。
一个或多个凸出元件26B从杯形表面24B向外延伸。图9和图10示出了四个凸出元件26B，但是可以包括诸如1、2、3、4、6或8个的任何数量的凸出元件。凸出元件26B是从杯形表面24B突然相对凸起的小楔形材料并且对着相对于轴线LA大约为1至30度的弧，四个凸出元件26B总共对着大约4至60度的弧。凸出元件26B具有第一壁30B，所述第一壁30B在弯曲的切割刃50B和杯形表面24B之间延伸，并且所述凸出元件26B还具有第二壁32B，所述第二壁32B相对于轴线LA径向延伸。第三壁34B在第一壁30B和第二壁32B的径向内部分之间延伸。在一些实施例中，凸出元件26B可以占据杯形表面24B的相对较小的部分并且按照如上关于切割元件4所述的方式从切割刃22B凹陷。在其它实施例中，切割元件的表面区域的至少60%、70%、80%或90%是光滑的杯形表面。
切割元件4B的远侧壁38B具有表面40B，所述表面40B相对于纵向轴线LA形成小于90度的角。在一些实施例中，表面40B所成的角度使得与边缘52B相比，边缘50B处于更远侧。整个表面40B仍可略微靠近切割刃22B但是从切割刃22B凹陷，使得整个表面40B与切割刃相距0.0010至0.0050英寸（0.0025至0.0127cm）的距离，所述距离包括0.0010、0.0020、0.0030、0.0040或0.0050英寸（0.0025、0.0051、0.0076、0.0101、或0.0127cm）。与形成在壁32B和远侧壁38B的相交部处的边缘52B相比，形成在壁30B和远侧壁38B的相交部处的边缘50B更靠近切割刃22B。在边缘50B附近，壁30B和表面40B之间的夹角大于90度。切割元件4B可以沿着任意方向旋转，使得凸出边缘50B可以是前边缘或后边缘。在一个实施例中，切割件4B沿着箭头R的方向旋转，使得边缘50B是前边缘。凸出边缘50B、52B可以距切割刃0.0010至0.0020英寸（0.0025至0.0051cm）。凸出元件26B可以全部以相同的方式形成或者彼此不同。例如，元件26B中的一些能够沿着不同的方向成角度，使得所述元件中的两个具有作为前边缘的凸出边缘50B以及元件26A中的两个具有作为后边缘的凸出边缘50B。在不背离本发明的各方面的前提下，凸出元件26B也可以对着不同的角度，具有不同高度或可以具有不同的径向长度。
在一个实施例中，切割件4B沿着箭头R的方向旋转，并且被向远侧推动，以便迫使杯形表面24B和凸出元件26B与诸如粥瘤或斑块的材料相接触。由于切割件轴线LA和表面40B之间的后角（reliefangle），因此凸出元件26B将趋于沿着边缘50B集中切割力。由于在边缘50B附近，壁30B和表面40B之间的夹角是钝角，因此切割件4B将趋于刮离诸如粥瘤或斑块的材料，而非切割进这种材料中。凸出元件26B所接触的材料将趋于被表面30B朝向轴线LA引导，所述表面30B从靠近边缘22B的相对切向的角度弯曲成靠近边缘34B的相对径向的角度。
参照图11和11A，示出了另一个切割元件4C。切割元件4C是切割元件4A的变型。该变型包括将底切41C添加到一个或多个凸出元件26A的前沿面，从而导致修改的凸出元件26C。当切割件4C沿着箭头T的方向旋转时，底切将材料颗粒引导到由切割件的杯形表面24A所限定的凹腔中并且朝向切割件的轴线LA。任选地，能够将底切分别应用到切割元件4、4B的一个或多个凸出元件26、26B的前沿面以及应用到切割元件4A的一个或多个凸出元件26A。
底切41C由壁30C限定，所述壁30C定向成与表面40A成锐角，所述表面40A与杯形表面24A相交并且与壁34A汇合。壁30C的平面也与轴线LA以小于5、10、15、或20度相交，使得当切割件4C沿着方向T旋转时，材料颗粒趋于在远离切割刃22A并且朝向轴线LA的方向上沿着壁30C行进。在一些实施例中，壁43C可以散置在壁30C和壁40A的相交部之间。可以以任何期望的前角定向壁43C，诸如例如，在凸出元件将趋于不刺入正被切割的材料的情况下，所述前角是负前角。
现在结合切割元件4来描述导管2的使用，但是这同样可应用于具有切割元件4A、切割元件4B、或者切割元件4C的导管2的使用。使用导丝（未示出）等以传统方式将导管2引入到患者体内。在切割元件处于图2的储存位置的情况下使导管2行进，直到导管定位于接近材料待移除的位置为止。然后，使切割元件4向近侧运动，使得斜坡16和凸轮表面14接合，以便使切割元件4运动到图3的切割位置，并且使导管2的尖端偏斜以使切割元件4朝向待切割的组织运动。切割元件4围绕纵向轴线LA旋转，并且然后导管2向远侧运动通过血管，使得切割元件4切割组织。由杯形表面24、一个或多个凸出元件26、由（切割元件4B的）弯曲表面30B、或由杯形表面、凸出元件、或弯曲表面的任何组合将已切割的组织引导到组织室12中。
更加具体地，当使用切割元件4B并且沿着箭头R的方向（图9）旋转切割元件时，切割刃22B切下较软的材料并且杯形表面将切下的材料引导到组织室12中；后角确保作用于导管上向远侧引导的力集中在凸出元件的边缘50B处而非分布在表面40B上；由于在边缘50B附近壁30B和表面40B之间的夹角是钝角，因此凸出元件26B将趋于刮离或粉碎诸如钙的较硬材料；弯曲表面30B朝向切割件轴线LA引导材料颗粒；并且弯曲表面30B在旋转时产生流体涡旋，所述流体涡旋趋于朝向切割件轴线LA引导材料颗粒并且向远侧进入组织室12中。
更加具体地，当使用诸如示出用于切割元件4C的底切并且沿着箭头T的方向旋转切割元件时（图11），底切41C朝向轴线LA沿着杯形表面远离切割刃22A、并且朝向切割元件的轴线LA径向地引导材料。
在另一个实施例中，图12和图13示出了具有切割元件104的粥样硬化切除导管102，所述切割元件104在大体沿着切割元件的轴线LA的方向上振动。粥样硬化切除导管102与粥样硬化切除导管2相似，其中相同或相似的附图标记指代相同或相似的结构，并且除非另有说明，关于粥样硬化切除导管2的相同或相似特征的所有讨论同样可应用于此。
粥样硬化切除导管102包括斜坡116和切割件104。切割元件104从储存位置向近侧运动（图12），使得切割元件104上的凸轮表面14接合导管102的主体8上的斜坡116。凸轮表面14和斜坡116之间的相互作用致使切割元件104运动到切割位置（图3）并且还致使尖端18发生偏斜，这趋于使切割元件104朝向待切割的组织运动。
切割件104包括凸轮表面14上的一个或多个凸出部分14a；此外，斜坡116包括斜坡表面116b中的一个或多个凹陷部116a。凹陷部和凸出部分的相对尺寸设计成使得凸出部分14a能够配合在凹陷部116a中。凹陷部116a还包括至少一个边缘116c。切割元件104的凸轮表面14被预载成与斜坡116压力接触。在一个实施例中，组装导管102，其中通过本领域中已知的手段使轴20处于拉伸状态以及导管主体8处于压缩状态，以便提供这种预载。在另一个实施例中，导管102包括弹簧（未示出），所述弹簧迫使凸出部分14a抵靠在斜坡表面116b上。切割件104包括杯形表面24和切割刃22并且可以以凸出元件26、26A、26B、或26C的任何混合和组合的方式包括0、1、2、3、4、6、或8个凸出元件。
在替代实施例中（未示出），切割件104包括一个或多个凸轮表面14上的凹陷部，并且斜坡116包括一个或多个斜坡表面116b上的凸出部分。在又一个实施例中（未示出），切割件104包括一个或多个凸轮表面14上的凸出部分，并且斜坡116包括一个或多个斜坡表面116b上的凸出部分。
在使用期间，使用导丝（未示出）等以传统方式将导管102引入到患者体内。导管2在切割元件处于图12的储存位置的情况下行进，直到导管定位在材料待移除的位置处。然后，使切割元件104向近侧运动，使得斜坡116和凸轮表面14接合，以使切割元件104运动到切割位置，并且使导管2的尖端偏斜，以便使切割元件104朝向待切割的组织运动（图3）。切割元件104围绕纵向轴线LA旋转，并且然后，导管102向远侧运动通过血管，以使切割元件104切割组织。杯形表面24将已切割的组织引导到组织室12中。在切割元件104围绕纵向轴线LA（沿着例如箭头S的方向）旋转的同时，凸出部分14a将沿着斜坡116的表面116b滑动，直到切割件104抵靠斜坡116的预载致使凸出部分14a进入到斜坡116的凹陷部116a中。切割元件104的进一步旋转致使凸出部分14a接触凹陷边缘116c并且从斜坡116的凹陷部116a弹出，从而使得切割件104对待移除的材料产生锤击状撞击。在待移除的材料具有易碎特征的情况中，材料将被压碎成更小的颗粒，从而有助于其移除。切割件104的重复旋转将使切割件104对待移除的材料产生重复锤击状击打。沿着大体平行于切割元件的轴线方向的振动将力施加在切割下的材料颗粒上，这将所述切割下的材料颗粒沿着远侧方向朝向收集室引导或者沿着双向引导。
以上描述和附图用于描述本发明的实施例并且并不旨在以任何方式限制本发明的范围。对本领域中的那些技术人员显而易见的是，在不背离本发明的精神和范围的前提下，可以做出多种变型和修改。因此，这表示，如果变型和修改落入随附权利要求及其等同物的范围内，则本发明涵盖该发明的变型和修改。而且，尽管相对于特定实施例，以上已经描述了材料和构造的选择方案，但是本领域的技术人员将理解的是，所述材料和构造可应用到所有实施例中。
Claims (14)
1.一种粥样硬化切除导管，所述粥样硬化切除导管包括：
主体，所述主体具有开口；
能够旋转的轴，所述能够旋转的轴联接到所述主体；
切割元件，所述切割元件联接到所述能够旋转的轴，以用于使所述切割元件围绕旋转轴线旋转，所述切割元件具有杯形表面和切割刃，所述杯形表面构造成当所述杯形表面沿着远侧方向运动时沿着远侧方向重新引导由所述切割刃切割下的组织；
组织收集室，所述组织收集室联接到所述主体并且定位在所述切割元件的远侧处；以及
凸出元件，所述凸出元件从所述切割元件的所述杯形表面向外延伸，所述凸出元件包括从所述杯形表面大体径向向外延伸的第一壁、远侧壁、以及形成在第一壁和远侧壁的相交部处的弯曲凸出元件切割刃，所述凸出元件构造成朝向所述切割元件的所述旋转轴线、导管的纵向轴线、或者所述组织收集室中的一个或多个引导切割下的材料颗粒。
2.根据权利要求1所述的粥样硬化切除导管，其中，所述凸出元件构造成朝向所述切割元件的所述旋转轴线引导切割下的材料颗粒。
3.根据权利要求2所述的粥样硬化切除导管，其中，所述切割刃位于所述切割元件的径向外边缘处。
4.根据权利要求3所述的粥样硬化切除导管，其中，所述第一壁是弯曲的，以朝向所述切割元件的旋转轴线引导切割下的材料颗粒。
5.根据权利要求4所述的粥样硬化切除导管，其中，所述第一壁从在所述切割元件的径向外边缘处与所述切割刃成相对切向的角度弯曲到更靠近所述切割元件的所述旋转轴线的相对径向的角度。
6.根据权利要求5所述的粥样硬化切除导管，其中，所述远侧壁从弯曲凸出元件切割刃延伸到后边缘，所述远侧壁相对于所述切割元件的所述旋转轴线形成小于90度的角。
7.根据权利要求6所述的粥样硬化切除导管，其中，所述弯曲凸出元件切割刃与所述后边缘相比位于更远侧。
8.根据权利要求7所述的粥样硬化切除导管，其中，所述弯曲凸出元件切割刃和所述切割元件的切割刃之间的最小径向距离小于所述后边缘和所述切割元件的所述切割刃之间的最小径向距离。
9.根据权利要求6所述的粥样硬化切除导管，其中，所述第一壁和所述远侧壁之间的夹角是钝角。
10.根据权利要求3所述的粥样硬化切除导管，其中，所述凸出元件从所述切割刃向近侧凹陷一纵向距离。
11.根据权利要求2所述的粥样硬化切除导管，其中，所述第一壁朝向所述切割元件的所述旋转轴线引导切割下的材料颗粒，并且其中，所述第一壁与所述杯形表面形成锐角，以便形成底切。
12.根据权利要求1所述的粥样硬化切除导管，其中，当沿着所述切割元件的所述旋转轴线观察时，对于所述切割元件的表面面积的至少90％来说，所述切割元件的所述杯形表面是光滑且不间断的。
13.根据权利要求1所述的粥样硬化切除导管，其中，所述多个凸出元件从所述杯形表面向外延伸，所述多个凸出元件是2、3、4、6或8个凸出元件。
14.根据权利要求1所述的粥样硬化切除导管，其中，所述切割元件构造成沿着基本平行于所述切割元件的所述旋转轴线的方向振动。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26586309P | 2009-12-02 | 2009-12-02 | |
| US61/265,863 | 2009-12-02 | ||
| PCT/US2010/058654 WO2011068932A1 (en) | 2009-12-02 | 2010-12-02 | Methods and devices for cutting tissue |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410823141.3A Division CN104490454A (zh) | 2009-12-02 | 2010-12-02 | 用于切割组织的方法和装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102695462A CN102695462A (zh) | 2012-09-26 |
| CN102695462B true CN102695462B (zh) | 2015-01-14 |
Family
ID=43646466
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201080054485.2A Active CN102695462B (zh) | 2009-12-02 | 2010-12-02 | 用于切割组织的方法和装置 |
| CN201410823141.3A Pending CN104490454A (zh) | 2009-12-02 | 2010-12-02 | 用于切割组织的方法和装置 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410823141.3A Pending CN104490454A (zh) | 2009-12-02 | 2010-12-02 | 用于切割组织的方法和装置 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US8496677B2 (zh) |
| EP (2) | EP2506783B1 (zh) |
| JP (1) | JP5499180B2 (zh) |
| KR (1) | KR20120079479A (zh) |
| CN (2) | CN102695462B (zh) |
| AU (1) | AU2010326063B2 (zh) |
| BR (1) | BR112012013389A2 (zh) |
| CA (1) | CA2781046C (zh) |
| RU (1) | RU2526915C2 (zh) |
| WO (1) | WO2011068932A1 (zh) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8328829B2 (en) | 1999-08-19 | 2012-12-11 | Covidien Lp | High capacity debulking catheter with razor edge cutting window |
| US7708749B2 (en) | 2000-12-20 | 2010-05-04 | Fox Hollow Technologies, Inc. | Debulking catheters and methods |
| US7713279B2 (en) | 2000-12-20 | 2010-05-11 | Fox Hollow Technologies, Inc. | Method and devices for cutting tissue |
| US6299622B1 (en) | 1999-08-19 | 2001-10-09 | Fox Hollow Technologies, Inc. | Atherectomy catheter with aligned imager |
| EP2353526B1 (en) | 2000-12-20 | 2013-09-04 | Covidien LP | Catheter for removing atheromatous or thrombotic occlusive material |
| US8246640B2 (en) | 2003-04-22 | 2012-08-21 | Tyco Healthcare Group Lp | Methods and devices for cutting tissue at a vascular location |
| US20070276419A1 (en) | 2006-05-26 | 2007-11-29 | Fox Hollow Technologies, Inc. | Methods and devices for rotating an active element and an energy emitter on a catheter |
| US8784440B2 (en) | 2008-02-25 | 2014-07-22 | Covidien Lp | Methods and devices for cutting tissue |
| US9788790B2 (en) | 2009-05-28 | 2017-10-17 | Avinger, Inc. | Optical coherence tomography for biological imaging |
| US8644913B2 (en) | 2011-03-28 | 2014-02-04 | Avinger, Inc. | Occlusion-crossing devices, imaging, and atherectomy devices |
| US9125562B2 (en) | 2009-07-01 | 2015-09-08 | Avinger, Inc. | Catheter-based off-axis optical coherence tomography imaging system |
| US8414604B2 (en) | 2008-10-13 | 2013-04-09 | Covidien Lp | Devices and methods for manipulating a catheter shaft |
| WO2010129075A1 (en) | 2009-04-28 | 2010-11-11 | Avinger, Inc. | Guidewire support catheter |
| AU2010241801B2 (en) | 2009-04-29 | 2013-04-11 | Covidien Lp | Methods and devices for cutting and abrading tissue |
| US8192452B2 (en) | 2009-05-14 | 2012-06-05 | Tyco Healthcare Group Lp | Easily cleaned atherectomy catheters and methods of use |
| WO2011003006A2 (en) | 2009-07-01 | 2011-01-06 | Avinger, Inc. | Atherectomy catheter with laterally-displaceable tip |
| CN102695462B (zh) | 2009-12-02 | 2015-01-14 | 泰科保健集团有限合伙公司 | 用于切割组织的方法和装置 |
| EP2509498B1 (en) | 2009-12-08 | 2020-09-16 | Avinger, Inc. | Devices for predicting and preventing restenosis |
| KR101398384B1 (ko) | 2009-12-11 | 2014-05-23 | 코비디엔 엘피 | 물질 포획 효율이 향상된 물질 제거 장치 및 사용 방법 |
| AU2011267862B2 (en) | 2010-06-14 | 2013-11-07 | Covidien Lp | Material removal device |
| WO2014039096A1 (en) | 2012-09-06 | 2014-03-13 | Avinger, Inc. | Re-entry stylet for catheter |
| US10548478B2 (en) | 2010-07-01 | 2020-02-04 | Avinger, Inc. | Balloon atherectomy catheters with imaging |
| US9345510B2 (en) | 2010-07-01 | 2016-05-24 | Avinger, Inc. | Atherectomy catheters with longitudinally displaceable drive shafts |
| US11382653B2 (en) | 2010-07-01 | 2022-07-12 | Avinger, Inc. | Atherectomy catheter |
| RU2539720C2 (ru) | 2010-10-28 | 2015-01-27 | Ковидиен Лп | Устройство для удаления материала и способ применения |
| CA2817213C (en) | 2010-11-11 | 2016-06-14 | Covidien Lp | Flexible debulking catheters with imaging and methods of use and manufacture |
| US9949754B2 (en) | 2011-03-28 | 2018-04-24 | Avinger, Inc. | Occlusion-crossing devices |
| JP5806407B2 (ja) | 2011-09-01 | 2015-11-10 | コヴィディエン リミテッド パートナーシップ | 螺旋駆動軸を有するカテーテルおよび製造方法 |
| WO2013059363A1 (en) | 2011-10-17 | 2013-04-25 | Avinger, Inc. | Atherectomy catheters and non-contact actuation mechanism for catheters |
| US9345406B2 (en) | 2011-11-11 | 2016-05-24 | Avinger, Inc. | Occlusion-crossing devices, atherectomy devices, and imaging |
| US9351757B2 (en) | 2012-01-17 | 2016-05-31 | Covidien Lp | Material removal device and method of use |
| EP2849636B1 (en) | 2012-05-14 | 2020-04-22 | Avinger, Inc. | Optical coherence tomography with graded index fiber for biological imaging |
| US11406412B2 (en) | 2012-05-14 | 2022-08-09 | Avinger, Inc. | Atherectomy catheters with imaging |
| US9345398B2 (en) | 2012-05-14 | 2016-05-24 | Avinger, Inc. | Atherectomy catheter drive assemblies |
| US9498247B2 (en) | 2014-02-06 | 2016-11-22 | Avinger, Inc. | Atherectomy catheters and occlusion crossing devices |
| US11284916B2 (en) | 2012-09-06 | 2022-03-29 | Avinger, Inc. | Atherectomy catheters and occlusion crossing devices |
| US9532844B2 (en) | 2012-09-13 | 2017-01-03 | Covidien Lp | Cleaning device for medical instrument and method of use |
| US9943329B2 (en) * | 2012-11-08 | 2018-04-17 | Covidien Lp | Tissue-removing catheter with rotatable cutter |
| WO2014093068A1 (en) | 2012-12-12 | 2014-06-19 | Covidien Lp | Tissue-removing catheter including screw blade and cutter driveshaft |
| US9636139B2 (en) | 2012-12-12 | 2017-05-02 | Covidien Lp | Tissue-removing catheter with ball and socket deployment mechanism |
| US9636138B2 (en) | 2012-12-12 | 2017-05-02 | Covidien Lp | Tissue-removing catheter including force-transmitting member for actuating a cutter housing |
| WO2014093154A1 (en) | 2012-12-12 | 2014-06-19 | Covidien Lp | Tissue-removing catheter including urging mechanism |
| JP6096318B2 (ja) * | 2012-12-12 | 2017-03-15 | コヴィディエン リミテッド パートナーシップ | 組織除去カテーテルのためのカッター |
| JP6502260B2 (ja) | 2012-12-12 | 2019-04-17 | コヴィディエン リミテッド パートナーシップ | 身体管腔のための組織除去カテーテル |
| EP2967367B1 (en) | 2013-03-15 | 2019-02-20 | Avinger, Inc. | Optical pressure sensor assembly |
| US9854979B2 (en) | 2013-03-15 | 2018-01-02 | Avinger, Inc. | Chronic total occlusion crossing devices with imaging |
| EP2967507B1 (en) | 2013-03-15 | 2018-09-05 | Avinger, Inc. | Tissue collection device for catheter |
| JP6517198B2 (ja) | 2013-07-08 | 2019-05-22 | アビンガー・インコーポレイテッドＡｖｉｎｇｅｒ， Ｉｎｃ． | 介入療法を案内する弾性層の識別 |
| US9526519B2 (en) * | 2014-02-03 | 2016-12-27 | Covidien Lp | Tissue-removing catheter with improved angular tissue-removing positioning within body lumen |
| EP3102127B1 (en) | 2014-02-06 | 2019-10-09 | Avinger, Inc. | Atherectomy catheter |
| WO2015200702A1 (en) | 2014-06-27 | 2015-12-30 | Covidien Lp | Cleaning device for catheter and catheter including the same |
| EP3166512B1 (en) | 2014-07-08 | 2020-08-19 | Avinger, Inc. | High speed chronic total occlusion crossing devices |
| JP6772161B2 (ja) * | 2015-02-20 | 2020-10-21 | コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． | 撮像を伴うアテローム切除装置 |
| US10314667B2 (en) | 2015-03-25 | 2019-06-11 | Covidien Lp | Cleaning device for cleaning medical instrument |
| US10905459B2 (en) * | 2015-06-08 | 2021-02-02 | Covidien Lp | Tissue-removing catheter, tissue-removing element, and method of making same |
| US10905458B2 (en) * | 2015-06-08 | 2021-02-02 | Covidien Lp | Tissue-removing catheter, tissue-removing element, and method of making same |
| WO2017011587A1 (en) | 2015-07-13 | 2017-01-19 | Avinger, Inc. | Micro-molded anamorphic reflector lens for image guided therapeutic/diagnostic catheters |
| US10292721B2 (en) | 2015-07-20 | 2019-05-21 | Covidien Lp | Tissue-removing catheter including movable distal tip |
| US10314664B2 (en) | 2015-10-07 | 2019-06-11 | Covidien Lp | Tissue-removing catheter and tissue-removing element with depth stop |
| WO2017091445A1 (en) * | 2015-11-25 | 2017-06-01 | George Crawford | Surgical instrument for penetration of tissue layers |
| JP6927986B2 (ja) | 2016-01-25 | 2021-09-01 | アビンガー・インコーポレイテッドＡｖｉｎｇｅｒ， Ｉｎｃ． | 遅延補正を備えたｏｃｔイメージングカテーテル |
| WO2017173370A1 (en) | 2016-04-01 | 2017-10-05 | Avinger, Inc. | Atherectomy catheter with serrated cutter |
| US10456161B2 (en) | 2016-04-14 | 2019-10-29 | Covidien Lp | Tissue-removing catheter with adjustment mechanism |
| US9962180B2 (en) | 2016-04-27 | 2018-05-08 | Covidien Lp | Catheter including drive assembly for rotating and reciprocating tissue-removing element |
| JP2019518543A (ja) | 2016-06-03 | 2019-07-04 | アビンガー・インコーポレイテッドＡｖｉｎｇｅｒ， Ｉｎｃ． | 着脱可能な遠位端部を有するカテーテル装置 |
| CN109414273B (zh) | 2016-06-30 | 2023-02-17 | 阿维格公司 | 具有可塑形的远侧头端的斑块切除导管 |
| EP3508149A4 (en) * | 2016-08-30 | 2020-04-29 | Terumo Kabushiki Kaisha | MEDICAL DEVICE AND TREATMENT METHOD |
| US10588656B2 (en) | 2017-11-10 | 2020-03-17 | Penumbra, Inc. | Thrombectomy catheter |
| US11793400B2 (en) | 2019-10-18 | 2023-10-24 | Avinger, Inc. | Occlusion-crossing devices |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4749376A (en) * | 1986-10-24 | 1988-06-07 | Intravascular Surgical Instruments, Inc. | Reciprocating working head catheter |
| US5507760A (en) * | 1993-11-09 | 1996-04-16 | Devices For Vascular Intervention, Inc. | Cutter device |
| CN1758880A (zh) * | 2003-03-10 | 2006-04-12 | 路径医学科技公司 | 具有不同的切割表面的介入导管 |
| CN201341930Y (zh) * | 2009-02-12 | 2009-11-11 | 王文华 | 血管腔内旋切导管 |
Family Cites Families (585)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1481078A (en) | 1922-11-24 | 1924-01-15 | Albertson & Company | Flexible shafting |
| US2178790A (en) | 1938-05-07 | 1939-11-07 | Abner E Henry | Cutting implement |
| US2701559A (en) | 1951-08-02 | 1955-02-08 | William A Cooper | Apparatus for exfoliating and collecting diagnostic material from inner walls of hollow viscera |
| US2850007A (en) | 1956-05-31 | 1958-09-02 | American Cyanamid Co | Biopsy device |
| US3064651A (en) | 1959-05-26 | 1962-11-20 | Henderson Edward | Hypodermic needle |
| US3082805A (en) | 1960-12-21 | 1963-03-26 | John H Royce | Tissue macerator |
| US3320957A (en) | 1964-05-21 | 1967-05-23 | Sokolik Edward | Surgical instrument |
| GB1235321A (en) | 1968-01-30 | 1971-06-09 | Nat Res Dev | Improvements in or relating to drills for clearing obstructions |
| US3732858A (en) | 1968-09-16 | 1973-05-15 | Surgical Design Corp | Apparatus for removing blood clots, cataracts and other objects from the eye |
| ES152231Y (es) | 1969-10-02 | 1970-07-01 | Ballestero Sierra | Un trocar perfeccionado. |
| US3749085A (en) | 1970-06-26 | 1973-07-31 | J Willson | Vascular tissue removing device |
| US3683891A (en) | 1970-06-26 | 1972-08-15 | Marshall Eskridge | Tissue auger |
| US3945375A (en) | 1972-04-04 | 1976-03-23 | Surgical Design Corporation | Rotatable surgical instrument |
| SU442795A1 (ru) | 1972-04-27 | 1974-09-15 | Л.С. Юхин | Устройство дл внутрисосудистых операций |
| US3815604A (en) | 1972-06-19 | 1974-06-11 | Malley C O | Apparatus for intraocular surgery |
| US3800783A (en) | 1972-06-22 | 1974-04-02 | K Jamshidi | Muscle biopsy device |
| US3831585A (en) | 1972-07-19 | 1974-08-27 | T Brondy | Retrograde renal biopsy device |
| JPS5042162A (zh) | 1973-08-21 | 1975-04-17 | ||
| US3837345A (en) | 1973-08-31 | 1974-09-24 | A Matar | Venous valve snipper |
| JPS5529376B2 (zh) | 1973-09-17 | 1980-08-02 | ||
| US3937222A (en) | 1973-11-09 | 1976-02-10 | Surgical Design Corporation | Surgical instrument employing cutter means |
| US3845375A (en) | 1973-11-09 | 1974-10-29 | Mclaughlin Ward & Co | Electronic rotational sensor |
| SU602175A1 (ru) * | 1974-06-24 | 1978-04-15 | Киевский научно-исследовательский институт клинической и экспериментальной хирургии | Устройство дл отслоени тромбов и атеросклеротических секвестров |
| US3976077A (en) | 1975-02-03 | 1976-08-24 | Kerfoot Jr Franklin W | Eye surgery device |
| US4007732A (en) | 1975-09-02 | 1977-02-15 | Robert Carl Kvavle | Method for location and removal of soft tissue in human biopsy operations |
| US4038985A (en) | 1975-10-07 | 1977-08-02 | Medico Developments, Inc. | Device for repairing arteries |
| US3995619A (en) | 1975-10-14 | 1976-12-07 | Glatzer Stephen G | Combination subcutaneous suture remover, biopsy sampler and syringe |
| US4020847A (en) | 1975-11-05 | 1977-05-03 | Clark Iii William T | Rotating cutter catheter |
| US4030503A (en) | 1975-11-05 | 1977-06-21 | Clark Iii William T | Embolectomy catheter |
| US4034744A (en) | 1975-11-13 | 1977-07-12 | Smith Kline Instruments, Inc. | Ultrasonic scanning system with video recorder |
| US4177797A (en) | 1977-03-04 | 1979-12-11 | Shelby M. Baylis | Rotary biopsy device and method of using same |
| US4112708A (en) | 1976-06-21 | 1978-09-12 | Nippon Cable Systems Inc. | Flexible drive cable |
| SU665908A1 (ru) | 1977-11-09 | 1979-06-05 | Silin Semen A | Устройство дл внутрисосудистых операций |
| US4210146A (en) | 1978-06-01 | 1980-07-01 | Anton Banko | Surgical instrument with flexible blade |
| US4306562A (en) | 1978-12-01 | 1981-12-22 | Cook, Inc. | Tear apart cannula |
| JPS5581633A (en) | 1978-12-15 | 1980-06-19 | Olympus Optical Co | Endoscope |
| US4273128A (en) | 1980-01-14 | 1981-06-16 | Lary Banning G | Coronary cutting and dilating instrument |
| US4306570A (en) | 1980-08-20 | 1981-12-22 | Matthews Larry S | Counter rotating biopsy needle |
| US4368730A (en) | 1981-02-12 | 1983-01-18 | Nigel Sharrock | Intravenous catheter |
| GB2093353B (en) | 1981-02-25 | 1984-09-19 | Dyonics Inc | A surgical instrument for arthroscopic arthroplasty |
| US4436091A (en) | 1981-03-20 | 1984-03-13 | Surgical Design Corporation | Surgical cutting instrument with release mechanism |
| JPS5887494U (ja) | 1981-12-05 | 1983-06-14 | 株式会社モリタ製作所 | 医療用小型モ−タの速度制御装置 |
| CH660015A5 (de) | 1982-02-01 | 1987-03-13 | Sandoz Ag | Polymerisat- und tensidhaltige praeparate, deren herstellung und verwendung. |
| US4445509A (en) | 1982-02-04 | 1984-05-01 | Auth David C | Method and apparatus for removal of enclosed abnormal deposits |
| US4692141A (en) | 1982-03-08 | 1987-09-08 | Mahurkar Sakharam D | Double lumen catheter |
| US4512344A (en) | 1982-05-12 | 1985-04-23 | Barber Forest C | Arthroscopic surgery dissecting apparatus |
| US4424045A (en) | 1982-05-24 | 1984-01-03 | Pennwalt Corporation | Rigid high speed flexible shaft casing assembly for tight radii installations |
| DE3235612A1 (de) | 1982-09-25 | 1984-03-29 | Bayer Ag, 5090 Leverkusen | Mikroemulsionen |
| US4490139A (en) | 1983-01-28 | 1984-12-25 | Eli Lilly And Company | Implant needle and method |
| US4936987A (en) | 1983-03-07 | 1990-06-26 | Calgon Corporation | Synergistic scale and corrosion inhibiting admixtures containing carboxylic acid/sulfonic acid polymers |
| US4603694A (en) | 1983-03-08 | 1986-08-05 | Richards Medical Company | Arthroscopic shaver |
| US4730616A (en) | 1983-08-12 | 1988-03-15 | Advanced Cardiovascular Systems, Inc. | Multiple probe angioplasty apparatus and method |
| FR2553851B1 (fr) | 1983-10-21 | 1988-10-14 | Aubecq Auxi Sa | Procede de fabrication d'une poulie a gorges multiples en v et poulie ainsi realisee |
| US5669936A (en) | 1983-12-09 | 1997-09-23 | Endovascular Technologies, Inc. | Endovascular grafting system and method for use therewith |
| US5104399A (en) | 1986-12-10 | 1992-04-14 | Endovascular Technologies, Inc. | Artificial graft and implantation method |
| DE3347671A1 (de) | 1983-12-31 | 1985-07-11 | Richard Wolf Gmbh, 7134 Knittlingen | Instrument zur entnahme von gewebeproben |
| US4631052A (en) | 1984-01-03 | 1986-12-23 | Intravascular Surgical Instruments, Inc. | Method and apparatus for surgically removing remote deposits |
| US4589412A (en) | 1984-01-03 | 1986-05-20 | Intravascular Surgical Instruments, Inc. | Method and apparatus for surgically removing remote deposits |
| US4842579B1 (en) | 1984-05-14 | 1995-10-31 | Surgical Systems & Instr Inc | Atherectomy device |
| US5007896A (en) | 1988-12-19 | 1991-04-16 | Surgical Systems & Instruments, Inc. | Rotary-catheter for atherectomy |
| US5002553A (en) | 1984-05-14 | 1991-03-26 | Surgical Systems & Instruments, Inc. | Atherectomy system with a clutch |
| US4732154A (en) | 1984-05-14 | 1988-03-22 | Surgical Systems & Instruments, Inc. | Rotary catheter system |
| US4894051A (en) | 1984-05-14 | 1990-01-16 | Surgical Systems & Instruments, Inc. | Atherectomy system with a biasing sleeve and method of using the same |
| US5024651A (en) | 1984-05-14 | 1991-06-18 | Surgical Systems & Instruments, Inc. | Atherectomy system with a sleeve |
| US4886490A (en) | 1984-05-14 | 1989-12-12 | Surgical Systems & Instruments, Inc. | Atherectomy catheter system and method of using the same |
| US4957482A (en) | 1988-12-19 | 1990-09-18 | Surgical Systems & Instruments, Inc. | Atherectomy device with a positive pump means |
| US4754755A (en) | 1984-05-14 | 1988-07-05 | Husted Royce Hill | Catheter with a rotary blade |
| US4883458A (en) | 1987-02-24 | 1989-11-28 | Surgical Systems & Instruments, Inc. | Atherectomy system and method of using the same |
| US5135531A (en) | 1984-05-14 | 1992-08-04 | Surgical Systems & Instruments, Inc. | Guided atherectomy system |
| US4979939A (en) | 1984-05-14 | 1990-12-25 | Surgical Systems & Instruments, Inc. | Atherectomy system with a guide wire |
| US4819634A (en) | 1984-05-14 | 1989-04-11 | Surgical Systems & Instruments | Rotary-catheter for atherectomy system |
| US4926858A (en) | 1984-05-30 | 1990-05-22 | Devices For Vascular Intervention, Inc. | Atherectomy device for severe occlusions |
| US4781186A (en) | 1984-05-30 | 1988-11-01 | Devices For Vascular Intervention, Inc. | Atherectomy device having a flexible housing |
| US4979951A (en) | 1984-05-30 | 1990-12-25 | Simpson John B | Atherectomy device and method |
| US4646719A (en) | 1984-06-11 | 1987-03-03 | Aries Medical Incorporated | Intra-aortic balloon catheter having flexible torque transmitting tube |
| USRE33258E (en) | 1984-07-23 | 1990-07-10 | Surgical Dynamics Inc. | Irrigating, cutting and aspirating system for percutaneous surgery |
| US4646736A (en) | 1984-09-10 | 1987-03-03 | E. R. Squibb & Sons, Inc. | Transluminal thrombectomy apparatus |
| US4705038A (en) | 1985-01-23 | 1987-11-10 | Dyonics, Inc. | Surgical system for powered instruments |
| US4649919A (en) | 1985-01-23 | 1987-03-17 | Precision Surgical Instruments, Inc. | Surgical instrument |
| US4653496A (en) | 1985-02-01 | 1987-03-31 | Bundy Mark A | Transluminal lysing system |
| US4745919A (en) | 1985-02-01 | 1988-05-24 | Bundy Mark A | Transluminal lysing system |
| US4686982A (en) | 1985-06-19 | 1987-08-18 | John Nash | Spiral wire bearing for rotating wire drive catheter |
| US4747406A (en) | 1985-02-13 | 1988-05-31 | Intravascular Surgical Instruments, Inc. | Shaft driven, flexible intravascular recanalization catheter |
| US4706671A (en) | 1985-05-02 | 1987-11-17 | Weinrib Harry P | Catheter with coiled tip |
| US4594057A (en) | 1985-06-10 | 1986-06-10 | Morgan Products, Inc. | Injector pump |
| US4664112A (en) | 1985-08-12 | 1987-05-12 | Intravascular Surgical Instruments, Inc. | Catheter based surgical methods and apparatus therefor |
| US4679558A (en) | 1985-08-12 | 1987-07-14 | Intravascular Surgical Instruments, Inc. | Catheter based surgical methods and apparatus therefor |
| US4790812A (en) | 1985-11-15 | 1988-12-13 | Hawkins Jr Irvin F | Apparatus and method for removing a target object from a body passsageway |
| US4696298A (en) | 1985-11-19 | 1987-09-29 | Storz Instrument Company | Vitrectomy cutting mechanism |
| US4646738A (en) | 1985-12-05 | 1987-03-03 | Concept, Inc. | Rotary surgical tool |
| AU607692B2 (en) | 1986-01-06 | 1991-03-14 | Boston Scientific Corporation Northwest Technology Center, Inc. | Transluminal microdissection device |
| CA1293663C (en) | 1986-01-06 | 1991-12-31 | David Christopher Auth | Transluminal microdissection device |
| US4669469A (en) | 1986-02-28 | 1987-06-02 | Devices For Vascular Intervention | Single lumen atherectomy catheter device |
| US4794931A (en) | 1986-02-28 | 1989-01-03 | Cardiovascular Imaging Systems, Inc. | Catheter apparatus, system and method for intravascular two-dimensional ultrasonography |
| US5000185A (en) | 1986-02-28 | 1991-03-19 | Cardiovascular Imaging Systems, Inc. | Method for intravascular two-dimensional ultrasonography and recanalization |
| US4771774A (en) | 1986-02-28 | 1988-09-20 | Devices For Vascular Intervention, Inc. | Motor drive unit |
| US4696667A (en) | 1986-03-20 | 1987-09-29 | Helmut Masch | Intravascular catheter and method |
| US4728319A (en) | 1986-03-20 | 1988-03-01 | Helmut Masch | Intravascular catheter |
| US5350395A (en) | 1986-04-15 | 1994-09-27 | Yock Paul G | Angioplasty apparatus facilitating rapid exchanges |
| US4757819A (en) | 1986-05-21 | 1988-07-19 | Olympus Optical Co., Ltd. | Ultrasonic endoscope |
| US4729763A (en) * | 1986-06-06 | 1988-03-08 | Henrie Rodney A | Catheter for removing occlusive material |
| US4765332A (en) | 1986-07-14 | 1988-08-23 | Medinnovations, Inc. | Pullback atherectomy catheter system |
| US4747821A (en) | 1986-10-22 | 1988-05-31 | Intravascular Surgical Instruments, Inc. | Catheter with high speed moving working head |
| SE455834B (sv) | 1986-10-31 | 1988-08-15 | Medinvent Sa | Anordning for transluminal implantation av en i huvudsak rorformig, radiellt expanderbar protes |
| US4733662A (en) | 1987-01-20 | 1988-03-29 | Minnesota Mining And Manufacturing Company | Tissue gripping and cutting assembly for surgical instrument |
| US4733622A (en) * | 1987-02-24 | 1988-03-29 | Ssmc Inc. | Thread end holder for sewing machine with thread winding bobbin |
| US4923462A (en) | 1987-03-17 | 1990-05-08 | Cordis Corporation | Catheter system having a small diameter rotatable drive member |
| US4846192A (en) | 1987-04-17 | 1989-07-11 | Eastman Kodak Company | Rearwardly acting surgical catheter |
| US4784636A (en) | 1987-04-30 | 1988-11-15 | Schneider-Shiley (U.S.A.) Inc. | Balloon atheroectomy catheter |
| US4817613A (en) | 1987-07-13 | 1989-04-04 | Devices For Vascular Intervention, Inc. | Guiding catheter |
| US4954338A (en) | 1987-08-05 | 1990-09-04 | Rohm And Haas Company | Microbicidal microemulsion |
| US4867157A (en) | 1987-08-13 | 1989-09-19 | Baxter Travenol Laboratories, Inc. | Surgical cutting instrument |
| US4819635A (en) | 1987-09-18 | 1989-04-11 | Henry Shapiro | Tubular microsurgery cutting apparatus |
| DE3732236C1 (de) | 1987-09-24 | 1988-12-15 | Rainer Dr Baumgart | Rekanalisationskatheter |
| US4844064A (en) | 1987-09-30 | 1989-07-04 | Baxter Travenol Laboratories, Inc. | Surgical cutting instrument with end and side openings |
| US5154705A (en) | 1987-09-30 | 1992-10-13 | Lake Region Manufacturing Co., Inc. | Hollow lumen cable apparatus |
| US5165421A (en) | 1987-09-30 | 1992-11-24 | Lake Region Manufacturing Co., Inc. | Hollow lumen cable apparatus |
| US4857046A (en) | 1987-10-21 | 1989-08-15 | Cordis Corporation | Drive catheter having helical pump drive shaft |
| US5047040A (en) | 1987-11-05 | 1991-09-10 | Devices For Vascular Intervention, Inc. | Atherectomy device and method |
| US4870953A (en) | 1987-11-13 | 1989-10-03 | Donmicheal T Anthony | Intravascular ultrasonic catheter/probe and method for treating intravascular blockage |
| US4887613A (en) | 1987-11-23 | 1989-12-19 | Interventional Technologies Inc. | Cutter for atherectomy device |
| NZ222930A (en) | 1987-12-15 | 1990-08-28 | Moffat Appliances Ltd | Gas infra-red burner in heat exchanger |
| US5053044A (en) | 1988-01-11 | 1991-10-01 | Devices For Vascular Intervention, Inc. | Catheter and method for making intravascular incisions |
| US4850957A (en) | 1988-01-11 | 1989-07-25 | American Biomed, Inc. | Atherectomy catheter |
| DE3801318A1 (de) | 1988-01-19 | 1989-07-27 | Stocksmeier Uwe | Medizinischer katheter mit schneidvorrichtung |
| US4886061A (en) * | 1988-02-09 | 1989-12-12 | Medinnovations, Inc. | Expandable pullback atherectomy catheter system |
| US4899757A (en) | 1988-02-22 | 1990-02-13 | Intertherapy, Inc. | Ultrasound imaging probe with zero dead space |
| ES2047586T3 (es) | 1988-03-04 | 1994-03-01 | Angiomed Ag | Procedimiento y dispositivo para retirar depositos de material en vasos y organos de seres vivos. |
| US4838268A (en) | 1988-03-07 | 1989-06-13 | Scimed Life Systems, Inc. | Non-over-the wire balloon catheter |
| US5183432A (en) | 1988-03-19 | 1993-02-02 | Nihonmatai Co., Ltd. | Floating body of sophisticated shape produced from a single sheet of film with a single sealing |
| US5372138A (en) | 1988-03-21 | 1994-12-13 | Boston Scientific Corporation | Acousting imaging catheters and the like |
| US5368035A (en) | 1988-03-21 | 1994-11-29 | Boston Scientific Corporation | Ultrasound imaging guidewire |
| US4935017A (en) | 1988-04-29 | 1990-06-19 | C. R. Bard, Inc. | Variable shaped catheter system and method for catheterization |
| US4950238A (en) | 1988-07-07 | 1990-08-21 | Clarence E. Sikes | Hydro-rotary vascular catheter |
| US4919133A (en) | 1988-08-18 | 1990-04-24 | Chiang Tien Hon | Catheter apparatus employing shape memory alloy structures |
| US5071425A (en) * | 1988-09-12 | 1991-12-10 | Devices For Vascular Intervention, Inc. | Atherectomy catheter and method of forming the same |
| GB8822149D0 (en) | 1988-09-21 | 1988-10-26 | Ciba Geigy Ag | Treatment of aqueous systems |
| DE8813144U1 (zh) | 1988-10-19 | 1988-12-15 | Guenther, Rolf W., Prof. Dr., 5100 Aachen, De | |
| GB8829182D0 (en) | 1988-12-14 | 1989-01-25 | Univ Birmingham | Surgical instrument |
| DE8900059U1 (zh) | 1989-01-04 | 1989-05-24 | Schneider (Europe) Ag, Zuerich, Ch | |
| WO1990007303A1 (en) | 1989-01-06 | 1990-07-12 | Angioplasty Systems, Inc. | Electrosurgical catheter for resolving atherosclerotic plaque |
| US4966604A (en) | 1989-01-23 | 1990-10-30 | Interventional Technologies Inc. | Expandable atherectomy cutter with flexibly bowed blades |
| US4986807A (en) | 1989-01-23 | 1991-01-22 | Interventional Technologies, Inc. | Atherectomy cutter with radially projecting blade |
| US5077506A (en) | 1989-02-03 | 1991-12-31 | Dyonics, Inc. | Microprocessor controlled arthroscopic surgical system |
| US5431673A (en) | 1989-02-17 | 1995-07-11 | American Biomed, Inc. | Distal atherectomy catheter |
| US5087265A (en) | 1989-02-17 | 1992-02-11 | American Biomed, Inc. | Distal atherectomy catheter |
| US4994067A (en) | 1989-02-17 | 1991-02-19 | American Biomed, Inc. | Distal atherectomy catheter |
| US4928693A (en) | 1989-03-13 | 1990-05-29 | Schneider (Usa), Inc. | Pressure monitor catheter |
| US5078723A (en) | 1989-05-08 | 1992-01-07 | Medtronic, Inc. | Atherectomy device |
| ATE134492T1 (de) | 1989-06-01 | 1996-03-15 | Schneider Europ Ag | Katheteranordnung mit einem führungsdraht sowie verfahren zur herstellung eines solchen führungsdrahtes |
| US5029588A (en) | 1989-06-15 | 1991-07-09 | Cardiovascular Imaging Systems, Inc. | Laser catheter with imaging capability |
| US5226910A (en) | 1989-07-05 | 1993-07-13 | Kabushiki Kaisha Topcon | Surgical cutter |
| US5269793A (en) | 1989-07-20 | 1993-12-14 | Devices For Vascular Intervention, Inc. | Guide wire systems for intravascular catheters |
| US5100426A (en) | 1989-07-26 | 1992-03-31 | Fts Engineering, Inc. | Catheter for performing an atherectomy procedure |
| US5115814A (en) | 1989-08-18 | 1992-05-26 | Intertherapy, Inc. | Intravascular ultrasonic imaging probe and methods of using same |
| US5211651A (en) | 1989-08-18 | 1993-05-18 | Evi Corporation | Catheter atherotome |
| US5282484A (en) | 1989-08-18 | 1994-02-01 | Endovascular Instruments, Inc. | Method for performing a partial atherectomy |
| US5226909A (en) | 1989-09-12 | 1993-07-13 | Devices For Vascular Intervention, Inc. | Atherectomy device having helical blade and blade guide |
| US4997435A (en) | 1989-09-25 | 1991-03-05 | Methodist Hospital Of Indiana Inc. | Percutaneous catheter with encapsulating receptacle |
| US5092839A (en) | 1989-09-29 | 1992-03-03 | Kipperman Robert M | Coronary thrombectomy |
| US5116352A (en) | 1989-10-06 | 1992-05-26 | Angiomed Ag | Apparatus for removing deposits from vessels |
| US5049124A (en) | 1989-10-14 | 1991-09-17 | Dow Corning Wright Corporation | Catheter drive apparatus having fluid delivery bearing |
| US5024234A (en) | 1989-10-17 | 1991-06-18 | Cardiovascular Imaging Systems, Inc. | Ultrasonic imaging catheter with guidewire channel |
| US5009659A (en) | 1989-10-30 | 1991-04-23 | Schneider (Usa) Inc. | Fiber tip atherectomy catheter |
| ZA908425B (en) | 1989-11-03 | 1991-07-31 | Rohm & Haas | Synergistic microbicidal combinations |
| US5505210A (en) | 1989-11-06 | 1996-04-09 | Mectra Labs, Inc. | Lavage with tissue cutting cannula |
| US5026384A (en) | 1989-11-07 | 1991-06-25 | Interventional Technologies, Inc. | Atherectomy systems and methods |
| US5019088A (en) | 1989-11-07 | 1991-05-28 | Interventional Technologies Inc. | Ovoid atherectomy cutter |
| US5085662A (en) | 1989-11-13 | 1992-02-04 | Scimed Life Systems, Inc. | Atherectomy catheter and related components |
| US5030201A (en) | 1989-11-24 | 1991-07-09 | Aubrey Palestrant | Expandable atherectomy catheter device |
| US5011490A (en) | 1989-12-07 | 1991-04-30 | Medical Innovative Technologies R&D Limited Partnership | Endoluminal tissue excision catheter system and method |
| US5178625A (en) | 1989-12-07 | 1993-01-12 | Evi Corporation | Catheter atherotome |
| US5003918A (en) | 1989-12-28 | 1991-04-02 | Interventional Technologies, Inc. | Apparatus for manufacturing atherectomy torque tubes |
| US5120323A (en) | 1990-01-12 | 1992-06-09 | Schneider (Usa) Inc. | Telescoping guide catheter system |
| US5916210A (en) | 1990-01-26 | 1999-06-29 | Intraluminal Therapeutics, Inc. | Catheter for laser treatment of atherosclerotic plaque and other tissue abnormalities |
| US5074841A (en) | 1990-01-30 | 1991-12-24 | Microcision, Inc. | Atherectomy device with helical cutter |
| US5152744A (en) | 1990-02-07 | 1992-10-06 | Smith & Nephew Dyonics | Surgical instrument |
| US5084010A (en) | 1990-02-20 | 1992-01-28 | Devices For Vascular Intervention, Inc. | System and method for catheter construction |
| US5092873A (en) | 1990-02-28 | 1992-03-03 | Devices For Vascular Intervention, Inc. | Balloon configuration for atherectomy catheter |
| US5222966A (en) | 1990-02-28 | 1993-06-29 | Devices For Vascular Intervention, Inc. | Balloon connection and inflation lumen for atherectomy catheter |
| US5366463A (en) | 1990-05-02 | 1994-11-22 | Ryan William J | Atherectomy catheter for the removal of atherosclerosis from within blood vessels |
| US5267955A (en) | 1990-05-10 | 1993-12-07 | Lake Region Manufacturing Company, Inc. | Atherectomy device |
| US5154724A (en) | 1990-05-14 | 1992-10-13 | Andrews Winston A | Atherectomy catheter |
| US5395311A (en) | 1990-05-14 | 1995-03-07 | Andrews; Winston A. | Atherectomy catheter |
| US5095911A (en) | 1990-05-18 | 1992-03-17 | Cardiovascular Imaging Systems, Inc. | Guidewire with imaging capability |
| US5558093A (en) | 1990-05-18 | 1996-09-24 | Cardiovascular Imaging Systems, Inc. | Guidewire with imaging capability |
| US5100424A (en) | 1990-05-21 | 1992-03-31 | Cardiovascular Imaging Systems, Inc. | Intravascular catheter having combined imaging abrasion head |
| US5674232A (en) | 1990-06-05 | 1997-10-07 | Halliburton; Alexander George | Catheter and method of use thereof |
| US5181920A (en) | 1990-06-08 | 1993-01-26 | Devices For Vascular Intervention, Inc. | Atherectomy device with angioplasty balloon and method |
| US5527298A (en) | 1990-06-11 | 1996-06-18 | Schneider (Usa) Inc. | Tracking guidewire |
| US5360443A (en) | 1990-06-11 | 1994-11-01 | Barone Hector D | Aortic graft for repairing an abdominal aortic aneurysm |
| JPH06114070A (ja) | 1990-06-22 | 1994-04-26 | Vance Prod Inc | 外科用組織切除装置 |
| US5064435A (en) | 1990-06-28 | 1991-11-12 | Schneider (Usa) Inc. | Self-expanding prosthesis having stable axial length |
| US5520189A (en) | 1990-07-13 | 1996-05-28 | Coraje, Inc. | Intravascular ultrasound imaging guidewire |
| CA2048120A1 (en) | 1990-08-06 | 1992-02-07 | William J. Drasler | Thrombectomy method and device |
| US5078722A (en) | 1990-08-14 | 1992-01-07 | Cordis Corporation | Method and apparatus for removing deposits from a vessel |
| US5100423A (en) | 1990-08-21 | 1992-03-31 | Medical Engineering & Development Institute, Inc. | Ablation catheter |
| US5127902A (en) | 1990-09-05 | 1992-07-07 | Medical Innovative Technologies R&D Limited Partnership | Apparatus and method for precisely controlling the excision of obstructive tissue in a human blood vessel |
| US5250065A (en) | 1990-09-11 | 1993-10-05 | Mectra Labs, Inc. | Disposable lavage tip assembly |
| US5114399A (en) | 1990-10-01 | 1992-05-19 | Intramed Laboratories | Surgical device |
| US5190528A (en) | 1990-10-19 | 1993-03-02 | Boston University | Percutaneous transseptal left atrial cannulation system |
| US5242460A (en) | 1990-10-25 | 1993-09-07 | Devices For Vascular Intervention, Inc. | Atherectomy catheter having axially-disposed cutting edge |
| US5527292A (en) | 1990-10-29 | 1996-06-18 | Scimed Life Systems, Inc. | Intravascular device for coronary heart treatment |
| US5496267A (en) | 1990-11-08 | 1996-03-05 | Possis Medical, Inc. | Asymmetric water jet atherectomy |
| DE4036570A1 (de) | 1990-11-16 | 1992-05-21 | Osypka Peter | Katheter zur verminderung oder beseitigung von verengungen in gefaessen |
| JP2550778B2 (ja) | 1990-11-30 | 1996-11-06 | 富士写真光機株式会社 | 超音波検査装置 |
| US5108500A (en) | 1990-12-10 | 1992-04-28 | Rohm And Haas Company | Stabilization of water insoluble 3-isothiazolones |
| US5112345A (en) | 1990-12-17 | 1992-05-12 | Interventional Technologies | Atherectomy cutter with arcuate blades |
| US5054492A (en) | 1990-12-17 | 1991-10-08 | Cardiovascular Imaging Systems, Inc. | Ultrasonic imaging catheter having rotational image correlation |
| US5110822A (en) | 1991-01-03 | 1992-05-05 | Rohm And Haas Company | Synergistic combinations of 4,5-dichloro-2-n-octyl-3-isothiazolone or 2-methyl-3-isothiazolone with ferric dimethyl dithiocarbamate fungicide |
| EP0525176A4 (en) | 1991-02-19 | 1994-07-13 | Fischell Robert | Improved apparatus and method for atherectomy |
| US5445155A (en) | 1991-03-13 | 1995-08-29 | Scimed Life Systems Incorporated | Intravascular imaging apparatus and methods for use and manufacture |
| US5295958A (en) | 1991-04-04 | 1994-03-22 | Shturman Cardiology Systems, Inc. | Method and apparatus for in vivo heart valve decalcification |
| CA2065634C (en) | 1991-04-11 | 1997-06-03 | Alec A. Piplani | Endovascular graft having bifurcation and apparatus and method for deploying the same |
| US6134003A (en) | 1991-04-29 | 2000-10-17 | Massachusetts Institute Of Technology | Method and apparatus for performing optical measurements using a fiber optic imaging guidewire, catheter or endoscope |
| DE69227902T3 (de) | 1991-04-29 | 2010-04-22 | Massachusetts Institute Of Technology, Cambridge | Vorrichtung für optische abbildung und messung |
| US6501551B1 (en) | 1991-04-29 | 2002-12-31 | Massachusetts Institute Of Technology | Fiber optic imaging endoscope interferometer with at least one faraday rotator |
| IT1249059B (it) | 1991-05-22 | 1995-02-11 | Rosa Antonio | Dissettore-scollatore ad ultrasuoni di placche aterosclerotiche |
| US5395335A (en) | 1991-05-24 | 1995-03-07 | Jang; G. David | Universal mode vascular catheter system |
| US5569275A (en) | 1991-06-11 | 1996-10-29 | Microvena Corporation | Mechanical thrombus maceration device |
| US5284486A (en) | 1991-06-11 | 1994-02-08 | Microvena Corporation | Self-centering mechanical medical device |
| US5263928A (en) | 1991-06-14 | 1993-11-23 | Baxter International Inc. | Catheter and endoscope assembly and method of use |
| US5273526A (en) | 1991-06-21 | 1993-12-28 | Lake Region Manufacturing Company, Inc. | Vascular occulusion removal devices and method |
| US5217474A (en) | 1991-07-15 | 1993-06-08 | Zacca Nadim M | Expandable tip atherectomy method and apparatus |
| US5336167A (en) | 1991-07-22 | 1994-08-09 | Theratek International, Inc. | Controller for intravascular catheter system |
| US5261877A (en) | 1991-07-22 | 1993-11-16 | Dow Corning Wright | Method of performing a thrombectomy procedure |
| US5242461A (en) | 1991-07-22 | 1993-09-07 | Dow Corning Wright | Variable diameter rotating recanalization catheter and surgical method |
| JPH0542162A (ja) | 1991-08-15 | 1993-02-23 | Nissho Corp | 塞栓切除カテ−テル |
| JP3084830B2 (ja) | 1991-08-29 | 2000-09-04 | 株式会社ニッショー | 塞栓切除カテ−テル |
| US5377682A (en) | 1991-09-05 | 1995-01-03 | Matsushita Electric Industrial Co., Ltd. | Ultrasonic probe for transmission and reception of ultrasonic wave and ultrasonic diagnostic apparatus including ultrasonic probe |
| US5285795A (en) | 1991-09-12 | 1994-02-15 | Surgical Dynamics, Inc. | Percutaneous discectomy system having a bendable discectomy probe and a steerable cannula |
| US5423846A (en) | 1991-10-21 | 1995-06-13 | Cathco, Inc. | Dottering auger catheter system |
| US5263959A (en) | 1991-10-21 | 1993-11-23 | Cathco, Inc. | Dottering auger catheter system and method |
| CA2081424C (en) | 1991-10-25 | 2008-12-30 | Timothy A. Chuter | Expandable transluminal graft prosthesis for repair of aneurysm |
| JPH0775611A (ja) | 1991-12-05 | 1995-03-20 | Daitoubou Shinsou Kk | 枕 |
| US5316023A (en) | 1992-01-08 | 1994-05-31 | Expandable Grafts Partnership | Method for bilateral intra-aortic bypass |
| US5224949A (en) | 1992-01-13 | 1993-07-06 | Interventional Technologies, Inc. | Camming device |
| US5224945A (en) | 1992-01-13 | 1993-07-06 | Interventional Technologies, Inc. | Compressible/expandable atherectomy cutter |
| DE69225812T2 (de) | 1992-01-13 | 1998-10-01 | Schneider Usa Inc | Schneideinrichtung für atherektomie-katheter |
| US5192291A (en) | 1992-01-13 | 1993-03-09 | Interventional Technologies, Inc. | Rotationally expandable atherectomy cutter assembly |
| ATE150953T1 (de) | 1992-01-13 | 1997-04-15 | Schneider Usa Inc | Chirurgisches schneidinstrument |
| US5250059A (en) * | 1992-01-22 | 1993-10-05 | Devices For Vascular Intervention, Inc. | Atherectomy catheter having flexible nose cone |
| US5318032A (en) | 1992-02-05 | 1994-06-07 | Devices For Vascular Intervention | Guiding catheter having soft tip |
| EP0626823B1 (en) | 1992-02-21 | 2000-04-19 | Boston Scientific Limited | Ultrasound imaging guidewire |
| US5295493A (en) | 1992-03-19 | 1994-03-22 | Interventional Technologies, Inc. | Anatomical guide wire |
| US5350390A (en) | 1992-03-25 | 1994-09-27 | Arieh Sher | Device for removal of intraluminal occlusions |
| US5176693A (en) | 1992-05-11 | 1993-01-05 | Interventional Technologies, Inc. | Balloon expandable atherectomy cutter |
| US5269759A (en) | 1992-07-28 | 1993-12-14 | Cordis Corporation | Magnetic guidewire coupling for vascular dilatation apparatus |
| US5306294A (en) | 1992-08-05 | 1994-04-26 | Ultrasonic Sensing And Monitoring Systems, Inc. | Stent construction of rolled configuration |
| US5707376A (en) | 1992-08-06 | 1998-01-13 | William Cook Europe A/S | Stent introducer and method of use |
| US5224488A (en) | 1992-08-31 | 1993-07-06 | Neuffer Francis H | Biopsy needle with extendable cutting means |
| US5383460A (en) | 1992-10-05 | 1995-01-24 | Cardiovascular Imaging Systems, Inc. | Method and apparatus for ultrasound imaging and atherectomy |
| US5312427A (en) | 1992-10-16 | 1994-05-17 | Shturman Cardiology Systems, Inc. | Device and method for directional rotational atherectomy |
| US5360432A (en) | 1992-10-16 | 1994-11-01 | Shturman Cardiology Systems, Inc. | Abrasive drive shaft device for directional rotational atherectomy |
| US5356418A (en) | 1992-10-28 | 1994-10-18 | Shturman Cardiology Systems, Inc. | Apparatus and method for rotational atherectomy |
| US5531690A (en) | 1992-10-30 | 1996-07-02 | Cordis Corporation | Rapid exchange catheter |
| US5336178A (en) | 1992-11-02 | 1994-08-09 | Localmed, Inc. | Intravascular catheter with infusion array |
| US5571122A (en) | 1992-11-09 | 1996-11-05 | Endovascular Instruments, Inc. | Unitary removal of plaque |
| US5643297A (en) | 1992-11-09 | 1997-07-01 | Endovascular Instruments, Inc. | Intra-artery obstruction clearing apparatus and methods |
| US5540707A (en) | 1992-11-13 | 1996-07-30 | Scimed Life Systems, Inc. | Expandable intravascular occlusion material removal devices and methods of use |
| US5501694A (en) | 1992-11-13 | 1996-03-26 | Scimed Life Systems, Inc. | Expandable intravascular occlusion material removal devices and methods of use |
| US5792157A (en) | 1992-11-13 | 1998-08-11 | Scimed Life Systems, Inc. | Expandable intravascular occlusion material removal devices and methods of use |
| US5372602A (en) | 1992-11-30 | 1994-12-13 | Device For Vascular Intervention, Inc. | Method of removing plaque using catheter cutter with torque control |
| EP0746373A1 (en) | 1992-12-01 | 1996-12-11 | Intelliwire, Inc. | Vibratory element for crossing stenoses |
| US5584842A (en) | 1992-12-02 | 1996-12-17 | Intramed Laboratories, Inc. | Valvulotome and method of using |
| US5318576A (en) | 1992-12-16 | 1994-06-07 | Plassche Jr Walter M | Endovascular surgery systems |
| US5373849A (en) | 1993-01-19 | 1994-12-20 | Cardiovascular Imaging Systems, Inc. | Forward viewing imaging catheter |
| US5620447A (en) | 1993-01-29 | 1997-04-15 | Smith & Nephew Dyonics Inc. | Surgical instrument |
| DE69409565T2 (de) | 1993-01-29 | 1998-10-01 | Smith & Nephew Inc | Schwenkbares gekrümmtes Instrument |
| DE9303531U1 (de) | 1993-03-11 | 1994-07-14 | Redha Falah | Medizinisches Instrument |
| US5378234A (en) | 1993-03-15 | 1995-01-03 | Pilot Cardiovascular Systems, Inc. | Coil polymer composite |
| CH685738A5 (fr) | 1993-03-25 | 1995-09-29 | Ferromec Sa | Instrument médical pour l'élimination de dépôts formés sur les parois intérieures des artères ou des veines. |
| US5372601A (en) | 1993-03-30 | 1994-12-13 | Lary; Banning G. | Longitudinal reciprocating incisor |
| US5322508A (en) | 1993-04-08 | 1994-06-21 | Cordis Corporation | Guidewire fluid delivery system and method of use |
| US5318528A (en) | 1993-04-13 | 1994-06-07 | Advanced Surgical Inc. | Steerable surgical devices |
| US5429136A (en) | 1993-04-21 | 1995-07-04 | Devices For Vascular Intervention, Inc. | Imaging atherectomy apparatus |
| US5716410A (en) | 1993-04-30 | 1998-02-10 | Scimed Life Systems, Inc. | Temporary stent and method of use |
| US5456667A (en) | 1993-05-20 | 1995-10-10 | Advanced Cardiovascular Systems, Inc. | Temporary stenting catheter with one-piece expandable segment |
| WO1994027501A1 (en) | 1993-05-24 | 1994-12-08 | Boston Scientific Corporation | Medical acoustic imaging catheter and guidewire |
| US5531685A (en) | 1993-06-11 | 1996-07-02 | Catheter Research, Inc. | Steerable variable stiffness device |
| CA2166466C (en) | 1993-07-03 | 2002-02-05 | Michael Ralph Rees | Improvements in or relating to angioplasty |
| US5514115A (en) | 1993-07-07 | 1996-05-07 | Device For Vascular Intervention, Inc. | Flexible housing for intracorporeal use |
| US5527325A (en) | 1993-07-09 | 1996-06-18 | Device For Vascular Intervention, Inc. | Atherectomy catheter and method |
| US5419774A (en) | 1993-07-13 | 1995-05-30 | Scimed Life Systems, Inc. | Thrombus extraction device |
| US5458585A (en) | 1993-07-28 | 1995-10-17 | Cardiovascular Imaging Systems, Inc. | Tracking tip for a work element in a catheter system |
| US5395313A (en) | 1993-08-13 | 1995-03-07 | Naves; Neil H. | Reciprocating arthroscopic shaver |
| US5441510A (en) | 1993-09-01 | 1995-08-15 | Technology Development Center | Bi-axial cutter apparatus for catheter |
| US5573008A (en) | 1993-10-29 | 1996-11-12 | Boston Scientific Corporation | Multiple biopsy sampling coring device |
| US5444078A (en) | 1993-10-01 | 1995-08-22 | Rohm And Haas Company | Fully water-dilutable microemulsions |
| US5456689A (en) | 1993-10-13 | 1995-10-10 | Arnold J. Kresch | Method and device for tissue resection |
| DE4335931B4 (de) | 1993-10-21 | 2006-10-12 | Cerasiv Gmbh Innovatives Keramik-Engineering | Hüftgelenkpfanne |
| AU1091095A (en) | 1993-11-08 | 1995-05-29 | Harrison M. Lazarus | Intraluminal vascular graft and method |
| US5443497A (en) | 1993-11-22 | 1995-08-22 | The Johns Hopkins University | Percutaneous prosthetic by-pass graft and method of use |
| US5427107A (en) | 1993-12-07 | 1995-06-27 | Devices For Vascular Intervention, Inc. | Optical encoder for catheter device |
| WO1995016141A1 (en) | 1993-12-09 | 1995-06-15 | Devices For Vascular Intervention, Inc. | Composite drive shaft |
| US5503155A (en) | 1994-01-26 | 1996-04-02 | Cardiovascular Imaging Systems, Inc. | Drive cable having internal lead wires |
| US5591127A (en) | 1994-01-28 | 1997-01-07 | Barwick, Jr.; Billie J. | Phacoemulsification method and apparatus |
| US5507769A (en) | 1994-10-18 | 1996-04-16 | Stentco, Inc. | Method and apparatus for forming an endoluminal bifurcated graft |
| US5413107A (en) | 1994-02-16 | 1995-05-09 | Tetrad Corporation | Ultrasonic probe having articulated structure and rotatable transducer head |
| US5485840A (en) | 1994-03-15 | 1996-01-23 | Bauman; Robert P. | Method of precise guidance for directional atherectomy using ultrasound |
| US5624457A (en) | 1994-04-07 | 1997-04-29 | Devices For Vascular Intervention | Directional atherectomy device with flexible housing |
| US5507795A (en) | 1994-04-29 | 1996-04-16 | Devices For Vascular Intervention, Inc. | Catheter with perfusion system |
| US5569279A (en) | 1994-04-29 | 1996-10-29 | Rainin; Edgar A. | Surgical abrading device |
| US5466382A (en) | 1994-05-03 | 1995-11-14 | Rohm And Haas Company | Synergistic microbicidal combinations containing 4,5-dichloro-2-n-octyl-3-isothiazolone and certain commercial biocides |
| USRE38335E1 (en) | 1994-05-24 | 2003-11-25 | Endius Incorporated | Surgical instrument |
| US5628761A (en) | 1994-07-08 | 1997-05-13 | Rizik; David G. | Guide wire passage creation device |
| US5531700A (en) | 1994-07-29 | 1996-07-02 | Cardiovascular Imaging Systems, Inc. | Convertible tip catheters and sheaths |
| US5575817A (en) | 1994-08-19 | 1996-11-19 | Martin; Eric C. | Aorto femoral bifurcation graft and method of implantation |
| US5609605A (en) | 1994-08-25 | 1997-03-11 | Ethicon, Inc. | Combination arterial stent |
| WO1996010366A1 (en) | 1994-10-03 | 1996-04-11 | Heart Technology, Inc. | Transluminal thrombectomy apparatus |
| US5571130A (en) | 1994-10-04 | 1996-11-05 | Advanced Cardiovascular Systems, Inc. | Atherectomy and prostectomy system |
| US5491524A (en) | 1994-10-05 | 1996-02-13 | Carl Zeiss, Inc. | Optical coherence tomography corneal mapping apparatus |
| US5549601A (en) | 1994-10-11 | 1996-08-27 | Devices For Vascular Intervention, Inc. | Delivery of intracorporeal probes |
| US5512044A (en) | 1994-10-11 | 1996-04-30 | Duer; Edward Y. | Embolic cutting catheter |
| US5507761A (en) | 1994-10-11 | 1996-04-16 | Duer; Edward Y. | Embolic cutting catheter |
| US6032673A (en) | 1994-10-13 | 2000-03-07 | Femrx, Inc. | Methods and devices for tissue removal |
| AU3783295A (en) | 1994-11-16 | 1996-05-23 | Advanced Cardiovascular Systems Inc. | Shape memory locking mechanism for intravascular stent |
| US5626562A (en) | 1994-11-28 | 1997-05-06 | Devices For Vascular Intervention | Drug delivery catheter |
| DE4444166C2 (de) | 1994-12-12 | 1998-09-24 | Urotech Med Tech Gmbh | Flexible Messervorrichtung für chirurgische Zwecke |
| US5643296A (en) | 1994-12-16 | 1997-07-01 | Devices For Vasclar Intervention | Intravascular catheter with guiding structure |
| US5584843A (en) | 1994-12-20 | 1996-12-17 | Boston Scientific Corporation | Shaped wire multi-burr rotational ablation device |
| US5836957A (en) | 1994-12-22 | 1998-11-17 | Devices For Vascular Intervention, Inc. | Large volume atherectomy device |
| US5632754A (en) | 1994-12-23 | 1997-05-27 | Devices For Vascular Intervention | Universal catheter with interchangeable work element |
| US6027450A (en) | 1994-12-30 | 2000-02-22 | Devices For Vascular Intervention | Treating a totally or near totally occluded lumen |
| CA2157697C (en) | 1995-01-10 | 2007-03-13 | Banning Gray Lary | Vascular incisor/dilator |
| US5700687A (en) | 1995-01-30 | 1997-12-23 | Bedminster Bioconversion Corporation | Odor control system |
| US5683449A (en) | 1995-02-24 | 1997-11-04 | Marcade; Jean Paul | Modular bifurcated intraluminal grafts and methods for delivering and assembling same |
| US5985397A (en) | 1995-03-20 | 1999-11-16 | Witt; Alvin E. | Coated synthetic resin board tiles |
| CZ287289B6 (en) | 1995-03-28 | 2000-10-11 | Straub Medical Ag | Catheter |
| EP0817594B1 (de) | 1995-03-28 | 2002-06-05 | Straub Medical AG | Katheter zum ablösen von abnormalen ablagerungen in menschlichen blutgefässen |
| US5728123A (en) | 1995-04-26 | 1998-03-17 | Lemelson; Jerome H. | Balloon actuated catheter |
| US5554163A (en) | 1995-04-27 | 1996-09-10 | Shturman Cardiology Systems, Inc. | Atherectomy device |
| US5556408A (en) | 1995-04-27 | 1996-09-17 | Interventional Technologies Inc. | Expandable and compressible atherectomy cutter |
| US5827229A (en) | 1995-05-24 | 1998-10-27 | Boston Scientific Corporation Northwest Technology Center, Inc. | Percutaneous aspiration thrombectomy catheter system |
| US5938645A (en) | 1995-05-24 | 1999-08-17 | Boston Scientific Corporation Northwest Technology Center Inc. | Percutaneous aspiration catheter system |
| US5596990A (en) | 1995-06-06 | 1997-01-28 | Yock; Paul | Rotational correlation of intravascular ultrasound image with guide catheter position |
| US5618293A (en) | 1995-06-06 | 1997-04-08 | Smith & Nephews Dyonics, Inc. | Surgical instrument |
| EP0836499A1 (en) | 1995-06-07 | 1998-04-22 | Cardima, Inc. | Guiding catheter for coronary sinus |
| US5779673A (en) | 1995-06-26 | 1998-07-14 | Focal, Inc. | Devices and methods for application of intraluminal photopolymerized gels |
| US5883458A (en) | 1995-07-31 | 1999-03-16 | Murata Manufacturing Co., Ltd. | Terminal for a piezoelectric device |
| US5681336A (en) | 1995-09-07 | 1997-10-28 | Boston Scientific Corporation | Therapeutic device for treating vien graft lesions |
| US6027460A (en) | 1995-09-14 | 2000-02-22 | Shturman Cardiology Systems, Inc. | Rotatable intravascular apparatus |
| US5707383A (en) | 1995-10-05 | 1998-01-13 | Xomed Surgical Products, Inc. | Method of removing soft tissue in the middle ear |
| US6283951B1 (en) | 1996-10-11 | 2001-09-04 | Transvascular, Inc. | Systems and methods for delivering drugs to selected locations within the body |
| CA2234389A1 (en) | 1995-10-13 | 1997-04-17 | Transvascular, Inc. | A device, system and method for interstitial transvascular intervention |
| US6302875B1 (en) | 1996-10-11 | 2001-10-16 | Transvascular, Inc. | Catheters and related devices for forming passageways between blood vessels or other anatomical structures |
| US6283983B1 (en) | 1995-10-13 | 2001-09-04 | Transvascular, Inc. | Percutaneous in-situ coronary bypass method and apparatus |
| WO1997013463A1 (en) | 1995-10-13 | 1997-04-17 | Transvascular, Inc. | Methods and apparatus for bypassing arterial obstructions and/or performing other transvascular procedures |
| US6375615B1 (en) | 1995-10-13 | 2002-04-23 | Transvascular, Inc. | Tissue penetrating catheters having integral imaging transducers and their methods of use |
| US5766192A (en) | 1995-10-20 | 1998-06-16 | Zacca; Nadim M. | Atherectomy, angioplasty and stent method and apparatus |
| US5843022A (en) | 1995-10-25 | 1998-12-01 | Scimied Life Systems, Inc. | Intravascular device utilizing fluid to extract occlusive material |
| US5989281A (en) | 1995-11-07 | 1999-11-23 | Embol-X, Inc. | Cannula with associated filter and methods of use during cardiac surgery |
| US5868685A (en) | 1995-11-14 | 1999-02-09 | Devices For Vascular Intervention | Articulated guidewire |
| US5697944A (en) | 1995-11-15 | 1997-12-16 | Interventional Technologies Inc. | Universal dilator with expandable incisor |
| US5827304A (en) | 1995-11-16 | 1998-10-27 | Applied Medical Resources Corporation | Intraluminal extraction catheter |
| US5688234A (en) | 1996-01-26 | 1997-11-18 | Cardiometrics Inc. | Apparatus and method for the treatment of thrombotic occlusions in vessels |
| US5733296A (en) | 1996-02-06 | 1998-03-31 | Devices For Vascular Intervention | Composite atherectomy cutter |
| US5695506A (en) | 1996-02-06 | 1997-12-09 | Devices For Vascular Intervention | Catheter device with a flexible housing |
| JPH09215753A (ja) | 1996-02-08 | 1997-08-19 | Schneider Usa Inc | チタン合金製自己拡張型ステント |
| US5800389A (en) | 1996-02-09 | 1998-09-01 | Emx, Inc. | Biopsy device |
| US5709698A (en) | 1996-02-26 | 1998-01-20 | Linvatec Corporation | Irrigating/aspirating shaver blade assembly |
| US6036707A (en) | 1996-03-07 | 2000-03-14 | Devices For Vascular Intervention | Catheter device having a selectively flexible housing |
| US5830224A (en) | 1996-03-15 | 1998-11-03 | Beth Israel Deaconess Medical Center | Catheter apparatus and methodology for generating a fistula on-demand between closely associated blood vessels at a pre-chosen anatomic site in-vivo |
| US5807329A (en) | 1996-05-07 | 1998-09-15 | Gelman; Martin L. | Displaceable catheter device |
| US6152909A (en) | 1996-05-20 | 2000-11-28 | Percusurge, Inc. | Aspiration system and method |
| US20010049517A1 (en) | 1997-03-06 | 2001-12-06 | Gholam-Reza Zadno-Azizi | Method for containing and removing occlusions in the carotid arteries |
| US5709701A (en) | 1996-05-30 | 1998-01-20 | Parodi; Juan C. | Apparatus for implanting a prothesis within a body passageway |
| US5779643A (en) | 1996-11-26 | 1998-07-14 | Hewlett-Packard Company | Imaging guidewire with back and forth sweeping ultrasonic source |
| WO1997046164A1 (en) | 1996-06-07 | 1997-12-11 | Scieran Technologies, Inc. | An apparatus and method for performing ophthalmic procedures |
| US5843161A (en) | 1996-06-26 | 1998-12-01 | Cordis Corporation | Endoprosthesis assembly for percutaneous deployment and method of deploying same |
| US5819738A (en) | 1996-07-03 | 1998-10-13 | Symbiosis Corporation | Jaw assembly having progressively larger teeth and endoscopic biopsy forceps instrument incorporating same |
| US5820592A (en) | 1996-07-16 | 1998-10-13 | Hammerslag; Gary R. | Angiographic and/or guide catheter |
| US5662671A (en) | 1996-07-17 | 1997-09-02 | Embol-X, Inc. | Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries |
| US5735816A (en) | 1996-07-23 | 1998-04-07 | Medtronic, Inc. | Spiral sheath retainer for autoperfusion dilatation catheter balloon |
| US5972019A (en) | 1996-07-25 | 1999-10-26 | Target Therapeutics, Inc. | Mechanical clot treatment device |
| US6830577B2 (en) | 1996-07-26 | 2004-12-14 | Kensey Nash Corporation | System and method of use for treating occluded vessels and diseased tissue |
| US6080170A (en) | 1996-07-26 | 2000-06-27 | Kensey Nash Corporation | System and method of use for revascularizing stenotic bypass grafts and other occluded blood vessels |
| US5827201A (en) | 1996-07-26 | 1998-10-27 | Target Therapeutics, Inc. | Micro-braided guidewire |
| US5779721A (en) | 1996-07-26 | 1998-07-14 | Kensey Nash Corporation | System and method of use for revascularizing stenotic bypass grafts and other blood vessels |
| US5676697A (en) | 1996-07-29 | 1997-10-14 | Cardiovascular Dynamics, Inc. | Two-piece, bifurcated intraluminal graft for repair of aneurysm |
| US7603166B2 (en) | 1996-09-20 | 2009-10-13 | Board Of Regents University Of Texas System | Method and apparatus for detection of vulnerable atherosclerotic plaque |
| US6682536B2 (en) | 2000-03-22 | 2004-01-27 | Advanced Stent Technologies, Inc. | Guidewire introducer sheath |
| US5713913A (en) | 1996-11-12 | 1998-02-03 | Interventional Technologies Inc. | Device and method for transecting a coronary artery |
| US6217595B1 (en) | 1996-11-18 | 2001-04-17 | Shturman Cardiology Systems, Inc. | Rotational atherectomy device |
| JP2001505460A (ja) | 1996-12-02 | 2001-04-24 | アンジオトラックス，インコーポレイテッド | 手術を経皮的に実施するための装置および方法 |
| US5941893A (en) | 1996-12-02 | 1999-08-24 | Angiotrax, Inc. | Apparatus for transluminally performing surgery |
| JP4200459B2 (ja) | 1997-01-06 | 2008-12-24 | 二郎 北村 | 免震装置または免震構造 |
| US6129734A (en) | 1997-01-21 | 2000-10-10 | Shturman Cardiology Systems, Inc. | Rotational atherectomy device with radially expandable prime mover coupling |
| US5893857A (en) | 1997-01-21 | 1999-04-13 | Shturman Cardiology Systems, Inc. | Handle for atherectomy device |
| DE19703779C2 (de) | 1997-02-01 | 2003-06-05 | Karlsruhe Forschzent | Verfahren und Vorrichtung zur Herstellung eines dispersen Gemisches |
| US5720735A (en) | 1997-02-12 | 1998-02-24 | Dorros; Gerald | Bifurcated endovascular catheter |
| AU6657098A (en) | 1997-02-12 | 1998-08-26 | Prolifix Medical, Inc. | Apparatus for removal of material from stents |
| US5882329A (en) | 1997-02-12 | 1999-03-16 | Prolifix Medical, Inc. | Apparatus and method for removing stenotic material from stents |
| US5968064A (en) | 1997-02-28 | 1999-10-19 | Lumend, Inc. | Catheter system for treating a vascular occlusion |
| US5741270A (en) | 1997-02-28 | 1998-04-21 | Lumend, Inc. | Manual actuator for a catheter system for treating a vascular occlusion |
| US6217549B1 (en) | 1997-02-28 | 2001-04-17 | Lumend, Inc. | Methods and apparatus for treating vascular occlusions |
| US6010449A (en) | 1997-02-28 | 2000-01-04 | Lumend, Inc. | Intravascular catheter system for treating a vascular occlusion |
| US6120516A (en) | 1997-02-28 | 2000-09-19 | Lumend, Inc. | Method for treating vascular occlusion |
| US5843103A (en) | 1997-03-06 | 1998-12-01 | Scimed Life Systems, Inc. | Shaped wire rotational atherectomy device |
| US6849068B1 (en) | 1997-03-06 | 2005-02-01 | Medtronic Ave, Inc. | Aspiration catheter |
| US5824055A (en) | 1997-03-25 | 1998-10-20 | Endotex Interventional Systems, Inc. | Stent graft delivery system and methods of use |
| US5772674A (en) | 1997-03-31 | 1998-06-30 | Nakhjavan; Fred K. | Catheter for removal of clots in blood vessels |
| US5810867A (en) | 1997-04-28 | 1998-09-22 | Medtronic, Inc. | Dilatation catheter with varied stiffness |
| US5911734A (en) | 1997-05-08 | 1999-06-15 | Embol-X, Inc. | Percutaneous catheter and guidewire having filter and medical device deployment capabilities |
| US5922003A (en) | 1997-05-09 | 1999-07-13 | Xomed Surgical Products, Inc. | Angled rotary tissue cutting instrument and method of fabricating the same |
| US5954745A (en) | 1997-05-16 | 1999-09-21 | Gertler; Jonathan | Catheter-filter set having a compliant seal |
| US6013072A (en) | 1997-07-09 | 2000-01-11 | Intraluminal Therapeutics, Inc. | Systems and methods for steering a catheter through body tissue |
| US6048349A (en) | 1997-07-09 | 2000-04-11 | Intraluminal Therapeutics, Inc. | Systems and methods for guiding a medical instrument through a body |
| EP1011856B1 (en) | 1997-08-05 | 2003-04-09 | Microfluidics International Corporation | Multiple stream high pressure mixer/reactor |
| GB9717580D0 (en) | 1997-08-19 | 1997-10-22 | Curry Paul | Device for opening blocked tubes |
| US6050949A (en) | 1997-09-22 | 2000-04-18 | Scimed Life Systems, Inc. | Catheher system having connectable distal and proximal portions |
| US6361545B1 (en) | 1997-09-26 | 2002-03-26 | Cardeon Corporation | Perfusion filter catheter |
| US5951480A (en) | 1997-09-29 | 1999-09-14 | Boston Scientific Corporation | Ultrasound imaging guidewire with static central core and tip |
| US6066149A (en) | 1997-09-30 | 2000-05-23 | Target Therapeutics, Inc. | Mechanical clot treatment device with distal filter |
| US5951482A (en) | 1997-10-03 | 1999-09-14 | Intraluminal Therapeutics, Inc. | Assemblies and methods for advancing a guide wire through body tissue |
| US6193676B1 (en) | 1997-10-03 | 2001-02-27 | Intraluminal Therapeutics, Inc. | Guide wire assembly |
| US6156046A (en) | 1997-11-07 | 2000-12-05 | Prolifix Medical, Inc. | Methods and systems for treating obstructions in a body lumen |
| US5947985A (en) | 1997-11-12 | 1999-09-07 | Imran; Mir A. | Apparatus and method for cleaning diseased vein grafts |
| US6183432B1 (en) | 1997-11-13 | 2001-02-06 | Lumend, Inc. | Guidewire and catheter with rotating and reciprocating symmetrical or asymmetrical distal tip |
| US6330884B1 (en) | 1997-11-14 | 2001-12-18 | Transvascular, Inc. | Deformable scaffolding multicellular stent |
| US5938671A (en) | 1997-11-14 | 1999-08-17 | Reflow, Inc. | Recanalization apparatus and devices for use therein and method |
| US5935108A (en) | 1997-11-14 | 1999-08-10 | Reflow, Inc. | Recanalization apparatus and devices for use therein and method |
| DE29722136U1 (de) | 1997-12-15 | 1999-04-15 | Ischinger Thomas Prof Dr | Vaskulärer Thrombektomiekatheter zur Entfernung von endoluminalem Thrombus |
| US6027514A (en) | 1997-12-17 | 2000-02-22 | Fox Hollow Technologies, Inc. | Apparatus and method for removing occluding material from body lumens |
| US6217527B1 (en) | 1998-09-30 | 2001-04-17 | Lumend, Inc. | Methods and apparatus for crossing vascular occlusions |
| US6231546B1 (en) | 1998-01-13 | 2001-05-15 | Lumend, Inc. | Methods and apparatus for crossing total occlusions in blood vessels |
| US6081738A (en) | 1998-01-15 | 2000-06-27 | Lumend, Inc. | Method and apparatus for the guided bypass of coronary occlusions |
| AU1927399A (en) | 1998-01-16 | 1999-08-02 | Lumend, Inc. | Catheter apparatus for treating arterial occlusions |
| US5865748A (en) | 1998-01-16 | 1999-02-02 | Guidant Corporation | Guided directional coronary atherectomy distal linear encoder |
| EP1054634A4 (en) | 1998-02-10 | 2006-03-29 | Artemis Medical Inc | CAPTURE APPARATUS AND METHOD OF USE |
| JP4157183B2 (ja) | 1998-02-17 | 2008-09-24 | オリンパス株式会社 | 内視鏡用処置具 |
| US6159195A (en) | 1998-02-19 | 2000-12-12 | Percusurge, Inc. | Exchange catheter and method of use |
| US20060074442A1 (en) | 2000-04-06 | 2006-04-06 | Revascular Therapeutics, Inc. | Guidewire for crossing occlusions or stenoses |
| US6398798B2 (en) | 1998-02-28 | 2002-06-04 | Lumend, Inc. | Catheter system for treating a vascular occlusion |
| US6454727B1 (en) | 1998-03-03 | 2002-09-24 | Senorx, Inc. | Tissue acquisition system and method of use |
| US6019778A (en) | 1998-03-13 | 2000-02-01 | Cordis Corporation | Delivery apparatus for a self-expanding stent |
| US6561998B1 (en) | 1998-04-07 | 2003-05-13 | Transvascular, Inc. | Transluminal devices, systems and methods for enlarging interstitial penetration tracts |
| US6001112A (en) | 1998-04-10 | 1999-12-14 | Endicor Medical, Inc. | Rotational atherectomy device |
| US6482217B1 (en) | 1998-04-10 | 2002-11-19 | Endicor Medical, Inc. | Neuro thrombectomy catheter |
| US6666874B2 (en) | 1998-04-10 | 2003-12-23 | Endicor Medical, Inc. | Rotational atherectomy system with serrated cutting tip |
| US6383195B1 (en) | 1998-04-13 | 2002-05-07 | Endoline, Inc. | Laparoscopic specimen removal apparatus |
| US6036646A (en) | 1998-07-10 | 2000-03-14 | Guided Therapy Systems, Inc. | Method and apparatus for three dimensional ultrasound imaging |
| US6106515A (en) | 1998-08-13 | 2000-08-22 | Intraluminal Therapeutics, Inc. | Expandable laser catheter |
| US6241744B1 (en) | 1998-08-14 | 2001-06-05 | Fox Hollow Technologies, Inc. | Apparatus for deploying a guidewire across a complex lesion |
| US6095990A (en) | 1998-08-31 | 2000-08-01 | Parodi; Juan Carlos | Guiding device and method for inserting and advancing catheters and guidewires into a vessel of a patient in endovascular treatments |
| US6022362A (en) | 1998-09-03 | 2000-02-08 | Rubicor Medical, Inc. | Excisional biopsy devices and methods |
| US6440147B1 (en) | 1998-09-03 | 2002-08-27 | Rubicor Medical, Inc. | Excisional biopsy devices and methods |
| US6620180B1 (en) | 1998-09-09 | 2003-09-16 | Medtronic Xomed, Inc. | Powered laryngeal cutting blade |
| JP2002526148A (ja) | 1998-10-02 | 2002-08-20 | ステリオタクシス インコーポレイテツド | 身体の腔および洞から物質を取り除くための磁気的にナビゲート可能なおよび／または制御可能な装置 |
| US6428551B1 (en) | 1999-03-30 | 2002-08-06 | Stereotaxis, Inc. | Magnetically navigable and/or controllable device for removing material from body lumens and cavities |
| AU2032400A (en) | 1998-11-25 | 2000-06-19 | Ball Semiconductor Inc. | Monitor for interventional procedures |
| US6228076B1 (en) | 1999-01-09 | 2001-05-08 | Intraluminal Therapeutics, Inc. | System and method for controlling tissue ablation |
| US6165199A (en) | 1999-01-12 | 2000-12-26 | Coaxia, Inc. | Medical device for removing thromboembolic material from cerebral arteries and methods of use |
| US6191862B1 (en) | 1999-01-20 | 2001-02-20 | Lightlab Imaging, Llc | Methods and apparatus for high speed longitudinal scanning in imaging systems |
| US7524289B2 (en) | 1999-01-25 | 2009-04-28 | Lenker Jay A | Resolution optical and ultrasound devices for imaging and treatment of body lumens |
| US6110121A (en) | 1999-01-25 | 2000-08-29 | Lenker; Jay Alan | Method and apparatus for obtaining improved resolution from intraluminal ultrasound |
| US6592526B1 (en) | 1999-01-25 | 2003-07-15 | Jay Alan Lenker | Resolution ultrasound devices for imaging and treatment of body lumens |
| US6113615A (en) | 1999-02-03 | 2000-09-05 | Scimed Life Systems, Inc. | Atherectomy burr including a bias wire |
| US6475226B1 (en) | 1999-02-03 | 2002-11-05 | Scimed Life Systems, Inc. | Percutaneous bypass apparatus and method |
| WO2000045691A2 (en) | 1999-02-04 | 2000-08-10 | Da Silva Branco Antonio Carlos | Kit for endovascular venous surgery |
| US6196963B1 (en) | 1999-03-02 | 2001-03-06 | Medtronic Ave, Inc. | Brachytherapy device assembly and method of use |
| DE19911777A1 (de) | 1999-03-17 | 2000-09-21 | Merck Patent Gmbh | Verfahren zur Herstellung von kosmetischen Formulierungen |
| US6245012B1 (en) | 1999-03-19 | 2001-06-12 | Nmt Medical, Inc. | Free standing filter |
| US6911026B1 (en) | 1999-07-12 | 2005-06-28 | Stereotaxis, Inc. | Magnetically guided atherectomy |
| US6066153A (en) | 1999-03-31 | 2000-05-23 | Lev; Avigdor | Device and method for resecting body tissues |
| US6277138B1 (en) | 1999-08-17 | 2001-08-21 | Scion Cardio-Vascular, Inc. | Filter for embolic material mounted on expandable frame |
| US6319275B1 (en) | 1999-04-07 | 2001-11-20 | Medtronic Ave, Inc. | Endolumenal prosthesis delivery assembly and method of use |
| DE19917148C2 (de) | 1999-04-16 | 2002-01-10 | Inst Mikrotechnik Mainz Gmbh | Verfahren und Mikrovermischer zur Herstellung einer Dispersion |
| US7526481B1 (en) | 1999-04-19 | 2009-04-28 | Oracle International Corporation | Web servers with queryable dynamic caches |
| US6790215B2 (en) | 1999-04-30 | 2004-09-14 | Edwards Lifesciences Corporation | Method of use for percutaneous material removal device and tip |
| US6238405B1 (en) | 1999-04-30 | 2001-05-29 | Edwards Lifesciences Corp. | Percutaneous material removal device and method |
| DE19925184A1 (de) | 1999-05-26 | 2000-11-30 | Schering Ag | Kontinuierliches Verfahren zur Herstellung von morphologisch einheitlichen Mikro- und Nanopartikeln mittels Mikromischer sowie nach diesem Verfahren hergestellte Partikel |
| US6126649A (en) | 1999-06-10 | 2000-10-03 | Transvascular, Inc. | Steerable catheter with external guidewire as catheter tip deflector |
| US6605061B2 (en) | 1999-07-14 | 2003-08-12 | Tricardia, L.L.C. | Catheter for drug injection in cardiovascular system |
| US6179859B1 (en) | 1999-07-16 | 2001-01-30 | Baff Llc | Emboli filtration system and methods of use |
| US6142987A (en) | 1999-08-03 | 2000-11-07 | Scimed Life Systems, Inc. | Guided filter with support wire and methods of use |
| US6445939B1 (en) | 1999-08-09 | 2002-09-03 | Lightlab Imaging, Llc | Ultra-small optical probes, imaging optics, and methods for using same |
| US6231549B1 (en) | 1999-08-17 | 2001-05-15 | Sherwood Services, Ag | Shim device for enteral feeding system |
| US7713279B2 (en) | 2000-12-20 | 2010-05-11 | Fox Hollow Technologies, Inc. | Method and devices for cutting tissue |
| US20030125757A1 (en) | 2000-12-20 | 2003-07-03 | Fox Hollow Technologies, Inc. | Debulking catheters and methods |
| US7887556B2 (en) | 2000-12-20 | 2011-02-15 | Fox Hollow Technologies, Inc. | Debulking catheters and methods |
| US7708749B2 (en) | 2000-12-20 | 2010-05-04 | Fox Hollow Technologies, Inc. | Debulking catheters and methods |
| US20030120295A1 (en) * | 2000-12-20 | 2003-06-26 | Fox Hollow Technologies, Inc. | Debulking catheters and methods |
| US8328829B2 (en) | 1999-08-19 | 2012-12-11 | Covidien Lp | High capacity debulking catheter with razor edge cutting window |
| US6299622B1 (en) | 1999-08-19 | 2001-10-09 | Fox Hollow Technologies, Inc. | Atherectomy catheter with aligned imager |
| US6638233B2 (en) | 1999-08-19 | 2003-10-28 | Fox Hollow Technologies, Inc. | Apparatus and methods for material capture and removal |
| US6447525B2 (en) | 1999-08-19 | 2002-09-10 | Fox Hollow Technologies, Inc. | Apparatus and methods for removing material from a body lumen |
| WO2001015609A1 (en) | 1999-08-31 | 2001-03-08 | Fox Hollow Technologies | Atherectomy catheter with a rotating and telescoping cutter |
| US6187025B1 (en) | 1999-09-09 | 2001-02-13 | Noble-Met, Ltd. | Vascular filter |
| CA2386158A1 (en) | 1999-09-17 | 2001-03-22 | Bacchus Vascular Inc. | Mechanical pump for removal of fragmented matter and methods of manufacture and use |
| US6533749B1 (en) | 1999-09-24 | 2003-03-18 | Medtronic Xomed, Inc. | Angled rotary tissue cutting instrument with flexible inner member |
| EP1231969A1 (en) | 1999-10-26 | 2002-08-21 | Mark Wilson Ian Webster | A guidewire positioning device |
| US6263236B1 (en) | 1999-11-29 | 2001-07-17 | Illumenex Corporation | Non-occlusive expandable catheter |
| AU2263001A (en) | 1999-12-16 | 2001-06-25 | Advanced Cardiovascular Systems Inc. | Catheter assembly and method for positioning the same at a bifurcated vessel |
| DE19961257C2 (de) | 1999-12-18 | 2002-12-19 | Inst Mikrotechnik Mainz Gmbh | Mikrovermischer |
| US6394976B1 (en) | 2000-01-31 | 2002-05-28 | Intraluminal Therapeutics, Inc. | Catheter for controlling the advancement of a guide wire |
| US6629953B1 (en) | 2000-02-18 | 2003-10-07 | Fox Hollow Technologies, Inc. | Methods and devices for removing material from a vascular site |
| GB2357762B (en) | 2000-03-13 | 2002-01-30 | Lundbeck & Co As H | Crystalline base of citalopram |
| US20010031981A1 (en) | 2000-03-31 | 2001-10-18 | Evans Michael A. | Method and device for locating guidewire and treating chronic total occlusions |
| US6565588B1 (en) | 2000-04-05 | 2003-05-20 | Pathway Medical Technologies, Inc. | Intralumenal material removal using an expandable cutting device |
| AU2001253173B2 (en) | 2000-04-05 | 2005-05-12 | Boston Scientific Limited | Intralumenal material removal systems and methods |
| US6627784B2 (en) | 2000-05-17 | 2003-09-30 | Hydro Dynamics, Inc. | Highly efficient method of mixing dissimilar fluids using mechanically induced cavitation |
| US6422736B1 (en) | 2000-06-21 | 2002-07-23 | Eastman Kodak Company | Scalable impeller apparatus for preparing silver halide grains |
| US6532380B1 (en) | 2000-06-30 | 2003-03-11 | Cedars Sinai Medical Center | Image guidance for coronary stent deployment |
| US6425870B1 (en) | 2000-07-11 | 2002-07-30 | Vermon | Method and apparatus for a motorized multi-plane transducer tip |
| US6497711B1 (en) | 2000-08-16 | 2002-12-24 | Scimed Life Systems, Inc. | Therectomy device having a light weight drive shaft and an imaging device |
| DE10041823C2 (de) | 2000-08-25 | 2002-12-19 | Inst Mikrotechnik Mainz Gmbh | Verfahren und statischer Mikrovermischer zum Mischen mindestens zweier Fluide |
| US6656195B2 (en) | 2000-09-22 | 2003-12-02 | Medtronic Xomed, Inc. | Flexible inner tubular members and rotary tissue cutting instruments having flexible inner tubular members |
| US20020058904A1 (en) | 2000-11-08 | 2002-05-16 | Robert Boock | Thrombus removal device |
| WO2002045598A2 (en) | 2000-12-05 | 2002-06-13 | Lumend, Inc. | Catheter system for vascular re-entry from a sub-intimal space |
| US20070049958A1 (en) | 2005-08-30 | 2007-03-01 | Arthrex, Inc. | Spiral cut curved blade |
| EP1767159A1 (en) | 2000-12-20 | 2007-03-28 | Fox Hollow Technologies Inc. | Catheter for removing atheromatous or thrombotic occlusive material |
| EP2353526B1 (en) | 2000-12-20 | 2013-09-04 | Covidien LP | Catheter for removing atheromatous or thrombotic occlusive material |
| US7699790B2 (en) | 2000-12-20 | 2010-04-20 | Ev3, Inc. | Debulking catheters and methods |
| US20040167554A1 (en) | 2000-12-20 | 2004-08-26 | Fox Hollow Technologies, Inc. | Methods and devices for reentering a true lumen from a subintimal space |
| US7169165B2 (en) | 2001-01-16 | 2007-01-30 | Boston Scientific Scimed, Inc. | Rapid exchange sheath for deployment of medical devices and methods of use |
| US6569177B1 (en) | 2001-01-19 | 2003-05-27 | Scimed Life Systems, Inc. | Ablation atherectomy burr |
| US6428552B1 (en) | 2001-01-22 | 2002-08-06 | Lumend, Inc. | Method and apparatus for crossing intravascular occlusions |
| EP1420844A2 (en) | 2001-04-16 | 2004-05-26 | Medtronic Percusurge, Inc. | Aspiration catheters and method of use |
| US20030023263A1 (en) | 2001-07-24 | 2003-01-30 | Incept Llc | Apparatus and methods for aspirating emboli |
| US6623437B2 (en) | 2001-08-28 | 2003-09-23 | Rex Medical, L.P. | Tissue biopsy apparatus |
| US6610059B1 (en) | 2002-02-25 | 2003-08-26 | Hs West Investments Llc | Endoscopic instruments and methods for improved bubble aspiration at a surgical site |
| US20030199747A1 (en) | 2002-04-19 | 2003-10-23 | Michlitsch Kenneth J. | Methods and apparatus for the identification and stabilization of vulnerable plaque |
| US6932502B2 (en) | 2002-05-01 | 2005-08-23 | Hewlett-Packard Development Company, L.P. | Mixing apparatus |
| US7153315B2 (en) | 2002-06-11 | 2006-12-26 | Boston Scientific Scimed, Inc. | Catheter balloon with ultrasonic microscalpel blades |
| EP1534152A1 (en) | 2002-07-13 | 2005-06-01 | Stryker Corporation | System and method for performing irrigated nose and throat surgery |
| US20040210245A1 (en) | 2002-07-26 | 2004-10-21 | John Erickson | Bendable needle with removable stylet |
| US20040049225A1 (en) | 2002-09-11 | 2004-03-11 | Denison Andy E. | Aspiration catheter |
| EP1551273A4 (en) | 2002-10-18 | 2011-04-06 | Arieh Sher | ATHEREOMETRY SYSTEM WITH IMAGING GUIDE WIRE |
| US7113093B2 (en) | 2003-02-21 | 2006-09-26 | Sensormatic Electronics Corporation | Integrated electronic article surveillance (EAS) and point of sale (POS) system and method |
| US20040193034A1 (en) | 2003-03-28 | 2004-09-30 | Lawrence Wasicek | Combined long rail/short rail IVUS catheter |
| US8246640B2 (en) | 2003-04-22 | 2012-08-21 | Tyco Healthcare Group Lp | Methods and devices for cutting tissue at a vascular location |
| US20050004594A1 (en) | 2003-07-02 | 2005-01-06 | Jeffrey Nool | Devices and methods for aspirating from filters |
| JP4026829B2 (ja) | 2003-07-24 | 2007-12-26 | ローム アンド ハース カンパニー | 殺微生物組成物 |
| JP2005068125A (ja) | 2003-08-21 | 2005-03-17 | Rohm & Haas Co | 殺生物剤配合物の調製方法 |
| US20050090849A1 (en) | 2003-10-22 | 2005-04-28 | Adams Kenneth M. | Angled tissue cutting instruments and method of fabricating angled tissue cutting instrument having flexible inner tubular members of tube and single wrap construction |
| US7338495B2 (en) | 2003-10-22 | 2008-03-04 | Medtronic Xomed, Inc. | Angled tissue cutting instruments having flexible inner tubular members of tube and sleeve construction |
| US7488322B2 (en) | 2004-02-11 | 2009-02-10 | Medtronic, Inc. | High speed surgical cutting instrument |
| US7959634B2 (en) | 2004-03-29 | 2011-06-14 | Soteira Inc. | Orthopedic surgery access devices |
| DE102004015639B4 (de) | 2004-03-31 | 2007-05-03 | Siemens Ag | Vorrichtung zum Durchführen einer "Cutting-Balloon"-Intervention mit IVUS-Überwachung |
| US7479148B2 (en) | 2004-11-08 | 2009-01-20 | Crescendo Technologies, Llc | Ultrasonic shear with asymmetrical motion |
| EP1903944B1 (en) | 2005-06-24 | 2017-04-19 | Volcano Corporation | Co-registration of graphical image data representing three-dimensional vascular features |
| KR100668852B1 (ko) | 2005-06-30 | 2007-01-16 | 주식회사 하이닉스반도체 | 듀티비 보정 장치 |
| DE102005045373A1 (de) | 2005-09-22 | 2007-04-05 | Siemens Ag | Kathetervorrichtung |
| US20080051812A1 (en) | 2006-08-01 | 2008-02-28 | Baxano, Inc. | Multi-Wire Tissue Cutter |
| US20070167824A1 (en) | 2005-11-30 | 2007-07-19 | Warren Lee | Method of manufacture of catheter tips, including mechanically scanning ultrasound probe catheter tip, and apparatus made by the method |
| DE102005059262B4 (de) | 2005-12-12 | 2008-02-07 | Siemens Ag | Kathetervorrichtung |
| DE102005059271B4 (de) | 2005-12-12 | 2019-02-21 | Siemens Healthcare Gmbh | Kathetervorrichtung |
| JP4504941B2 (ja) * | 2006-04-25 | 2010-07-14 | テルモ株式会社 | 血栓吸引カテーテル |
| US7951161B2 (en) | 2006-05-09 | 2011-05-31 | Medrad, Inc. | Atherectomy system having a variably exposed cutter |
| US20070276419A1 (en) | 2006-05-26 | 2007-11-29 | Fox Hollow Technologies, Inc. | Methods and devices for rotating an active element and an energy emitter on a catheter |
| US8361094B2 (en) | 2006-06-30 | 2013-01-29 | Atheromed, Inc. | Atherectomy devices and methods |
| CN101511284B (zh) * | 2006-06-30 | 2011-11-09 | 阿瑟罗迈德公司 | 动脉粥样硬化切除术装置和方法 |
| US20090018566A1 (en) | 2006-06-30 | 2009-01-15 | Artheromed, Inc. | Atherectomy devices, systems, and methods |
| US8007506B2 (en) | 2006-06-30 | 2011-08-30 | Atheromed, Inc. | Atherectomy devices and methods |
| US7981128B2 (en) | 2006-06-30 | 2011-07-19 | Atheromed, Inc. | Atherectomy devices and methods |
| US20080045986A1 (en) | 2006-06-30 | 2008-02-21 | Atheromed, Inc. | Atherectomy devices and methods |
| US8628549B2 (en) | 2006-06-30 | 2014-01-14 | Atheromed, Inc. | Atherectomy devices, systems, and methods |
| US7842009B2 (en) | 2006-10-04 | 2010-11-30 | Pathway Medical Technologies, Inc. | Interventional catheters incorporating aspiration and/or infusion systems |
| US8211025B2 (en) | 2006-10-20 | 2012-07-03 | General Electric Company | Four-way steerable catheter system and method of use |
| EP2104460A2 (en) | 2006-12-29 | 2009-09-30 | Vascure Ltd. | Atherectomy methods and apparatus |
| KR101529333B1 (ko) | 2007-01-19 | 2015-06-16 | 써니브룩 헬스 사이언시즈 센터 | 초음파와 광학 영상 진단 수단이 결합된 영상 탐침 장치 |
| US20080208227A1 (en) | 2007-02-23 | 2008-08-28 | Terumo Cardiovascular Systems Corporation | Self-contained dissector/harvester device |
| WO2008124650A1 (en) | 2007-04-06 | 2008-10-16 | Interlace Medical, Inc. | Method, system and device for tissue removal |
| US20080312673A1 (en) | 2007-06-05 | 2008-12-18 | Viswanathan Raju R | Method and apparatus for CTO crossing |
| US8475478B2 (en) | 2007-07-05 | 2013-07-02 | Cardiovascular Systems, Inc. | Cleaning apparatus and method for high-speed rotational atherectomy devices |
| US8236016B2 (en) | 2007-10-22 | 2012-08-07 | Atheromed, Inc. | Atherectomy devices and methods |
| US8070762B2 (en) | 2007-10-22 | 2011-12-06 | Atheromed Inc. | Atherectomy devices and methods |
| US20090138031A1 (en) | 2007-11-24 | 2009-05-28 | Tsukernik Vladimir B | Thrombectomy catheter with a helical cutter |
| US8784440B2 (en) * | 2008-02-25 | 2014-07-22 | Covidien Lp | Methods and devices for cutting tissue |
| WO2009111670A1 (en) | 2008-03-06 | 2009-09-11 | Ev3 Endovascular, Inc. | Image enhancement and application functionality for medical and other uses |
| US8062316B2 (en) | 2008-04-23 | 2011-11-22 | Avinger, Inc. | Catheter system and method for boring through blocked vascular passages |
| US20090275966A1 (en) | 2008-05-05 | 2009-11-05 | Miroslav Mitusina | Flexible inner members having flexible regions comprising a plurality of intertwined helical cuts |
| US9186170B2 (en) | 2008-06-05 | 2015-11-17 | Cardiovascular Systems, Inc. | Bidirectional expandable head for rotational atherectomy device |
| US20100030216A1 (en) | 2008-07-30 | 2010-02-04 | Arcenio Gregory B | Discectomy tool having counter-rotating nucleus disruptors |
| JP5042162B2 (ja) | 2008-08-12 | 2012-10-03 | 株式会社日立ハイテクノロジーズ | 半導体加工方法 |
| US8414604B2 (en) | 2008-10-13 | 2013-04-09 | Covidien Lp | Devices and methods for manipulating a catheter shaft |
| DE102009014489B4 (de) | 2009-03-23 | 2011-03-10 | Siemens Aktiengesellschaft | Katheter und medizinische Vorrichtung |
| AU2010241801B2 (en) | 2009-04-29 | 2013-04-11 | Covidien Lp | Methods and devices for cutting and abrading tissue |
| US8192452B2 (en) | 2009-05-14 | 2012-06-05 | Tyco Healthcare Group Lp | Easily cleaned atherectomy catheters and methods of use |
| WO2011003006A2 (en) | 2009-07-01 | 2011-01-06 | Avinger, Inc. | Atherectomy catheter with laterally-displaceable tip |
| US8142464B2 (en) | 2009-07-21 | 2012-03-27 | Miroslav Mitusina | Flexible inner member having a flexible region composed of longitudinally and rotationally offset partial circumferential cuts |
| WO2011040250A1 (ja) | 2009-09-29 | 2011-04-07 | コニカミノルタホールディングス株式会社 | アクチュエータ、駆動装置、およびカメラモジュール |
| CN102695462B (zh) | 2009-12-02 | 2015-01-14 | 泰科保健集团有限合伙公司 | 用于切割组织的方法和装置 |
| KR101398384B1 (ko) | 2009-12-11 | 2014-05-23 | 코비디엔 엘피 | 물질 포획 효율이 향상된 물질 제거 장치 및 사용 방법 |
-
2010
- 2010-12-02 CN CN201080054485.2A patent/CN102695462B/zh active Active
- 2010-12-02 EP EP10788197.1A patent/EP2506783B1/en active Active
- 2010-12-02 RU RU2012121387/14A patent/RU2526915C2/ru not_active IP Right Cessation
- 2010-12-02 BR BR112012013389A patent/BR112012013389A2/pt not_active Application Discontinuation
- 2010-12-02 KR KR1020127014254A patent/KR20120079479A/ko not_active Application Discontinuation
- 2010-12-02 CN CN201410823141.3A patent/CN104490454A/zh active Pending
- 2010-12-02 WO PCT/US2010/058654 patent/WO2011068932A1/en active Application Filing
- 2010-12-02 US US12/958,488 patent/US8496677B2/en active Active
- 2010-12-02 JP JP2012542175A patent/JP5499180B2/ja active Active
- 2010-12-02 EP EP14194521.2A patent/EP2913013B1/en active Active
- 2010-12-02 CA CA2781046A patent/CA2781046C/en not_active Expired - Fee Related
- 2010-12-02 AU AU2010326063A patent/AU2010326063B2/en active Active
-
2013
- 2013-06-13 US US13/917,186 patent/US9687267B2/en active Active
-
2017
- 2017-05-23 US US15/602,378 patent/US10499947B2/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4749376A (en) * | 1986-10-24 | 1988-06-07 | Intravascular Surgical Instruments, Inc. | Reciprocating working head catheter |
| US5507760A (en) * | 1993-11-09 | 1996-04-16 | Devices For Vascular Intervention, Inc. | Cutter device |
| CN1758880A (zh) * | 2003-03-10 | 2006-04-12 | 路径医学科技公司 | 具有不同的切割表面的介入导管 |
| CN201341930Y (zh) * | 2009-02-12 | 2009-11-11 | 王文华 | 血管腔内旋切导管 |
Also Published As
| Publication number | Publication date |
|---|---|
| US10499947B2 (en) | 2019-12-10 |
| EP2913013A1 (en) | 2015-09-02 |
| CA2781046C (en) | 2014-09-16 |
| US9687267B2 (en) | 2017-06-27 |
| US20110130777A1 (en) | 2011-06-02 |
| WO2011068932A1 (en) | 2011-06-09 |
| RU2012121387A (ru) | 2014-01-20 |
| CN104490454A (zh) | 2015-04-08 |
| US20170281223A1 (en) | 2017-10-05 |
| JP5499180B2 (ja) | 2014-05-21 |
| EP2913013B1 (en) | 2016-11-09 |
| EP2506783A1 (en) | 2012-10-10 |
| JP2013512736A (ja) | 2013-04-18 |
| KR20120079479A (ko) | 2012-07-12 |
| US20140163590A1 (en) | 2014-06-12 |
| EP2506783B1 (en) | 2016-06-29 |
| CN102695462A (zh) | 2012-09-26 |
| AU2010326063A1 (en) | 2012-06-07 |
| CA2781046A1 (en) | 2011-06-09 |
| BR112012013389A2 (pt) | 2018-03-06 |
| US8496677B2 (en) | 2013-07-30 |
| AU2010326063B2 (en) | 2013-07-04 |
| RU2526915C2 (ru) | 2014-08-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102695462B (zh) | 用于切割组织的方法和装置 | |
| US10555753B2 (en) | Methods and devices for cutting and abrading tissue | |
| US10219824B2 (en) | Methods and devices for cutting tissue | |
| EP3446648B1 (en) | Tissue-removing catheter with rotatable cutter |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |