CA2119109A1 - Bioadhesive ophthalmic insert - Google Patents

Bioadhesive ophthalmic insert

Info

Publication number
CA2119109A1
CA2119109A1 CA002119109A CA2119109A CA2119109A1 CA 2119109 A1 CA2119109 A1 CA 2119109A1 CA 002119109 A CA002119109 A CA 002119109A CA 2119109 A CA2119109 A CA 2119109A CA 2119109 A1 CA2119109 A1 CA 2119109A1
Authority
CA
Canada
Prior art keywords
bioadhesive
biocompatible polymer
ophthalmic insert
insert
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002119109A
Other languages
French (fr)
Other versions
CA2119109C (en
Inventor
Florian Gurtler
Robert Gurny
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vetoquinol SA
Original Assignee
Vetoquinol SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vetoquinol SA filed Critical Vetoquinol SA
Priority to CA002119109A priority Critical patent/CA2119109C/en
Publication of CA2119109A1 publication Critical patent/CA2119109A1/en
Application granted granted Critical
Publication of CA2119109C publication Critical patent/CA2119109C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants

Abstract

A bioadhesive ophthalmic insert is described which is intended more particularly for the prolonged and controlled release of a medicinal substance. The insert comprises a composite polymeric material matrix in which the medicinal substance is incorporated.
The composite polymeric material matrix comprises a water-soluble biocompatible polymer and a bioadhesive biocompatible polymer and, where applicable, a water-insoluble biocompatible polymer.
CA002119109A 1994-03-15 1994-03-15 Bioadhesive ophthalmic insert Expired - Fee Related CA2119109C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002119109A CA2119109C (en) 1994-03-15 1994-03-15 Bioadhesive ophthalmic insert

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002119109A CA2119109C (en) 1994-03-15 1994-03-15 Bioadhesive ophthalmic insert

Publications (2)

Publication Number Publication Date
CA2119109A1 true CA2119109A1 (en) 1995-09-16
CA2119109C CA2119109C (en) 2002-11-12

Family

ID=4153174

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002119109A Expired - Fee Related CA2119109C (en) 1994-03-15 1994-03-15 Bioadhesive ophthalmic insert

Country Status (1)

Country Link
CA (1) CA2119109C (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7678827B2 (en) 2002-07-15 2010-03-16 Alcon, Inc. Non-polymeric lipophilic pharmaceutical implant compositions for intraocular use

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7678827B2 (en) 2002-07-15 2010-03-16 Alcon, Inc. Non-polymeric lipophilic pharmaceutical implant compositions for intraocular use
US8178576B2 (en) 2002-07-15 2012-05-15 Novartis Ag Non-polymeric lipophilic pharmaceutical implant compositions for intraocular use

Also Published As

Publication number Publication date
CA2119109C (en) 2002-11-12

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed